Gene AqueK113 (A.queenslandica)

AqueK113

Species: A.queenslandica
Alias: AqueK113
External Links:
Annotation:

Classification

Group: CMGC
Family: DYRK
Subfamily: DYRK2

Sequence

Name Sequence Type Origin Length Description Download
AqueK113.AA Protein None 625 None Fasta, JSON
AqueK113.kin_dom Protein Kinase Domain None 314 None Fasta, JSON

Protein domain

Protein domains of AqueK113.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase AqueK113.AA DYRK2 219-532 65 4.1e-231 759.39 In-house 1-318 (318) Show / Hide 
Range on Protein: 219-532
Range on HMM: 1-318/318
Sequence Identity: 65% (208 aa)

YEVLKVLGKGSFGQVLKAYDHKMQTHIALKVVRNEKRFHRQAQEEVKILEHLRRQDKDNAHNIIHMIDHFTFRNHVCITFELLSMNLYELIKKNKFQGFS
||.|.|.||||||||.|.|||| ..|.|.|..||.||||.||.||..||.|.|||||||..|..|| | |.||||.|||||||||||||.||||.|||||
YEILEVIGKGSFGQVVKCYDHKTKQHVAIKMIRNKKRFHNQAYEEIRILHHIRRQDKDNTMNCVHMLDYFYFRNHHCITFELLSMNLYEYIKKNHFQGFS

LALVRKFAHSILQCLDSLYRNRIIHCDLKPENILLKQPGRSGIKVIDFGSSCYEYQ-RVYTYIQSRFYRAPEVILGGKYGMSIDMWSFGCILAELLTGYP
|.|||.|||||||||. |..|.|||||||||||||||..|||||||||||||.|.| |.||||||||||||||||||||||.|||||||||.|||.||||
LQLVRRFAHSILQCLRFLHKNNIIHCDLKPENILLKQWNRSGIKVIDFGSSCFEHQYRIYTYIQSRFYRAPEVILGGKYGMAIDMWSFGCIMAELYTGYP

LFPGEDEGDQLACMMEVLGLPSQKMIEST-----KRGRTFFSSKGHPRYTTVNINPDGTASYTGGRSRRGKFRGPPGTKDMSRALKGCDDPQFLDFLRHC
|||||.|.||.||||||||.|..|...       .| ..|| |.. ..|    ...|..    .....|.. |.|||.|... .||||.|. |.||.. |
LFPGENENDQFACMMEVLGMPPKKFFDTWFYIHCFRRKYFFNSHCFEWYC--TFMTDHSMEIPKHYKNRHGKRRPPGSKSWKSVLKGCEDENFIDFIKRC

LEWDPAIRMTPPQALRHPWL
.||||. |||| |||.|||.
FEWDPSERMTPSQALKHPWI
Kinase AqueK113.AA DYRK 219-532 57 6.00000000001e-201 673.86 In-house 1-320 (320) Show / Hide 
Range on Protein: 219-532
Range on HMM: 1-320/320
Sequence Identity: 57% (186 aa)

YEVLKVLGKGSFGQVLKAYDHKMQTHIALKVVRNEKRFHRQAQEEVKILEHLRRQDKDNAHNIIHMIDHFTFRNHVCITFELLSMNLYELIKKNKFQGF-
||.|...|||||||| |..||| . ..|.|..||.||||||||.|.||||.|..||.|. ....|| |.|..|||.||.||||||||||..|.|.|||| 
YEILEYIGKGSFGQVVKCWDHKTNEMVAIKIIRNNKRFHRQAQIEIKILEYLNQQDPDDKYHCVHMYDYFYHRNHLCIVFELLSMNLYEFLKNNHFQGFF

SLALVRKFAHSILQCLDSLYRN-RIIHCDLKPENILLKQP-GRSGIKVIDFGSSCYEYQRVYTYIQSRFYRAPEVILGGKYGMSIDMWSFGCILAELLTG
|| ||||||..||.||. |..| .|||||||||||.|||| ..|.||||||||||.| ||.|||||||||||||||||..|...|||||.|||||||.||
SLNLVRKFAQQILTCLKFLHKNENIIHCDLKPENIMLKQPRNKSTIKVIDFGSSCFEHQRIYTYIQSRFYRAPEVILGCPYCYAIDMWSLGCILAELFTG

YPLFPGEDEGDQLACMMEVLGLPSQKMIEST--KRGRTFFSSKGHPRYTTVNINPDGTA------SYTGGRSRRGKFRGPPGTKDMSRALKGCDDPQFLD
.||||||.| |||||.|||||.|...||..   .| ..|| .   ..|...  ....         . . ...| . |.|||...   ... ||| ||.|
WPLFPGENEYDQLACIMEVLGMPPKWMIDKGRCRRKHKFFDC---FMYCECDEWTKQNKITDHYMTPKCHPTKR-GQRRPPGRRNWDPRHQ-CDDHQFKD

FLRHCLEWDPAIRMTPPQALRHPWL
|.. ||.|||. |.|| |||.|||.
FIKKCLQWDPHKRITPSQALQHPWF
Kinase AqueK113.AA CMGC 219-532 22 1.4e-130 431.66 In-house 1-513 (513) Show / Hide 
Range on Protein: 219-532
Range on HMM: 1-513/513
Sequence Identity: 22% (119 aa)

YEVLKVLGKGSFGQVLKAYD--------------HKMQTHIALKVVRNEKRFHRQAQ-------------EEVKILEHLR-RQDKDN----------AHN
||..|..|.|..|.| |..|              |. . ..|.| ..|.. ...||.              |.|||.||. ..|. |           ||
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDP-NWQRRDDPDNKHHN

-IIHMIDHFTFRN-----------------HVCITFELLSMNLYELIKKNK--------------------------FQGFSLALVRKFAHSILQCLD--
 |....|.|...|                 |... ||.. ..||..||.|.                           . |.. ..| ... ||..|.  
NIVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSEHENKHPHRRPPHNIKYFMI-HIR-YMYQILRGLKLK

SLYRNR--IIHCDLKPENILLKQPGRS------------------GIKVIDFGSSCYEYQR------------------------VYTYIQSRFYRAPEV
 . ...  |||.||||||||. . ...                   .|..|||..... ..                         ..|...|.|||||.
YCHSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEI

ILGGK----------YGMSIDMWSFGCILAELLTG--------YPLFPGEDE-----------GDQLACMMEVLGLPSQKMIESTK-------RGRTFFS
.|| |          |. .|||||.|||.||..||        .|||||..|            |||.....||| |. .||...|       . .....
LLGWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPT-WMIQKGKRHFNFCKHEEEWPN

SKGHPRY----------TTVNINPDGTASYTGGRSRRGKFRGPPGTKDMSRALKG------------------------------CDDPQFLDFLRHCLE
 .. |.|          |  |. ...   |     | ......| .. . .. ..                              |.|||..|.|  .|.
MIKLPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQ

WDPAIRMTPPQALRHPWL
.||. |.|. |||.||..
YDPDKRITAEQALQHPYF
Kinase AqueK113.AA DYRK1 219-532 45 8e-117 394.41 In-house 1-321 (321) Show / Hide 
Range on Protein: 219-532
Range on HMM: 1-321/321
Sequence Identity: 45% (146 aa)

YEVLKVLGKGSFGQVLKAYDHKMQTHIALKVVRNEKRFHRQAQEEVKILEHLRRQDKDNAHNIIHMIDHFTFRNHVCITFELLSMNLYELIKKNKFQGFS
||.   .|||||||| |||||. | ..|.|...| | |  ||| |...|| . ..||..  .|.|.  || ||||.|. ||||| |||.|..  .|.| |
YEIDSLIGKGSFGQVVKAYDHQEQEYVAIKIIKNKKPFYNQAQIEIRLLELMNKHDKEMKYYIVHLKRHFMFRNHLCLVFELLSYNLYDLLRNTHFRGVS

LALVRKFAHSILQCLDSLYRN--RIIHCDLKPENILLKQPGRSGIKVIDFGSSCYEYQRVYTYIQSRFYRAPEVILGGKYGMSIDMWSFGCILAELLTGY
| |.||||. ... |  .      |||||||||||||  | || ||.|||||||   ||.| ||||||||.|||.|| .| |.||||| |||| |. || 
LNLTRKFAQQMCTALLFMSTPELDIIHCDLKPENILLCNPKRSAIKIIDFGSSCQLGQRIYQYIQSRFYRSPEVLLGIEYDMAIDMWSLGCILVEMHTGE

PLFPGEDEGDQLACMMEVLGLPSQKMIESTKRGRTFFSSKGHPRYTTVNINPDGTASYTGGRSRR-----GKFRGPPGTKDMSRALKGCDDP-QFLDFLR
||| | .| ||.  ..||||.| ..||... . . .|  . .  ..    . |.   |   . |.     |   | ||.. .  .     |. .| | ..
PLFSGSNEVDQMNKIVEVLGMPPKHMIDQAPKAHKYFEKDPDNTWYCKKTR-DKKKHYKEPCTRKLHEILGVETGGPGGRRKGEPGHSVEDYLKFKDLIK

HCLEWDPAIRMTPPQALRHPWL
. |..||. |.|| .||.|...
RMLQYDPKQRITPYYALQHSFF
Kinase AqueK113.AA YAK 219-453 46 4.4e-99 335.48 In-house 1-239 (347) Show / Hide 
Range on Protein: 219-453
Range on HMM: 1-239/347
Sequence Identity: 46% (112 aa)

YEVLKVLGKGSFGQVLKAYDHKMQTHIALKVVRNEKRFHRQAQEEVKILEHLRRQDKDNAHN----IIHMIDHFTFRNHVCITFELLSMNLYELIKKNKF
| || .||.| |||| |         .| ||. |   .  ||  |..||. |  |   |  |    |. |.| | ..|| |. ||.||.||||..| |||
YIVLDMLGQGTFGQVVKCQNCDTNELFAVKVIKNRQAYFQQAKNEIQILRVLNQQHDPNNKNYQKHILRMYDFFVHKNHFCLVFEMLSNNLYEYLKQNKF

QGFSLALVRKFAHSILQCLDSLYRNRIIHCDLKPENILLKQPGRSGIKVIDFGSSCYEYQRVYTYIQSRFYRAPEVILGGKYGMSIDMWSFGCILAELLT
 |||  |.| .  .||  .  |   .|||||||||||.|..| .  ||.|||||||.| . ||||||.|.||.||.|..  |  |||||| |||.|||  
CGFSFQLIRQWTKQILDGMCVLENKQIIHCDLKPENIMLCKPNKPEIKIIDFGSSCQEKKMVYTYIQQRHYRSPEIIVWMIYCTSIDMWSLGCIVAELFL

GYPLFPGEDEGDQLACMMEVLGLPSQKMIESTKRGRTFF
| |.|||  | .|.    ..|| |   ||.  .    .|
GLPIFPGNSEYNQIKRIIDMLGYPPSWMIDQGRFKNKYF
Kinase AqueK113.AA S_TKc 219-532 26 1.3e-91 311.63 SMART 1-231 (231) Show / Hide 
Range on Protein: 219-532
Range on HMM: 1-231/231
Sequence Identity: 26% (88 aa)

YEVLKVLGKGSFGQVLKAYDHKMQTHIALKVVRNEKRFHRQAQEEVKILEHLRRQDKDNAHNIIHMIDHFTFRNHVCITFELLSM---NLYELIKKNKFQ
||.|...|||.||.| |....| . . |.|...      .... |..||..       .  ||....|.|   .|... .|...    .|...|||.. .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-------HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRH

G----FSLALVRKFAHSILQCLDSLYRNRIIHCDLKPENILLKQPGRSGIKVIDFGSSCYEYQRVYTYIQSRFYRAPEVILGGKYGM-SIDMWSFGCILA
|    |.   .|.... |.. |. . ...|||.||||||||| .     ||..|||...      .|.. ...|.||||.   .||  ..|.||.||||.
GLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE----HIKICDFGLARQL----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILY

ELLTGYPLFPGEDEGDQLACMMEVLGLPSQKMIESTKRGRTFFSSKGHPRYTTVNINPDGTASYTGGRSRRGKFRGPPGTKDMSRALKGCDDPQFLDFLR
|.|.|||.||      |.. |....|                                                                 .|...||.|
EMLCGYPPFP------QMQMMFKKIG-----------------------------------------------------------------SPEAKDFIR

HCLEWDPAIRMTPPQALR-------HPWL
.||..||. |.|  .||.       |||.
KCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK113.AA HIPK 219-453 41 1.1e-73 231.27 In-house 1-237 (329) Show / Hide 
Range on Protein: 219-453
Range on HMM: 1-237/329
Sequence Identity: 41% (99 aa)

YEVLKVLGKGSFGQVLKAYDHKMQTHIALKVVRNEKRFHRQAQEEVKILEHLRRQDKDNAHNIIHMIDHFTFRNHVCITFELLSMNLYELIKKNKFQGFS
|||| .||.| |||| |.  .  .  .|.|. .|.  . || | ||.||. |. .. |..| .. . . |  .||.|. ||.|  |||.  |.|||    
YEVLEFLGRGTFGQVVKCWKRGTNEMVAIKILKNHPYYARQGQIEVSILHCLSQENADEYH-FVRAYECFHHKNHTCLVFEMLEQNLYDFQKQNKFMPLP

LALVRKFAHSILQCLDSLYRNRIIHCDLKPENILLKQPGRSG--IKVIDFGSSCYEYQRVY-TYIQSRFYRAPEVILGGKYGMSIDMWSFGCILAELLTG
|  .|     .|  |  |    .|| |||||||.|  | |    .|||||||  .  . |  ||.|||.|||||.||| ..  ..|||| ||..|||  |
LKHIRPILQQVLTALMKLKELGLIHADLKPENIMLVDPTRCPYRVKVIDFGSASHVSKVVCNTYLQSRYYRAPEIILGLPFCENHDMWSLGCVIAELFLG

YPLFPGEDEGDQLACMMEVLGLPSQKMIESTKRGRTFF
 ||.|| || ||   . .  .|| . ....  .   ||
WPLYPGADEYDQIRYICQTQHLPHEHLLHAACKKHRFF
Kinase AqueK113.AA Pkinase 219-532 26 6.3e-68 236.77 Pfam 1-293 (293) Show / Hide 
Range on Protein: 219-532
Range on HMM: 1-293/293
Sequence Identity: 26% (89 aa)

YEVLKVLGKGSFGQVLKAYDHKMQTHIALKVVRNEKRFHRQAQE-----EVKILEHLRRQDKDNAHNIIHMIDHFTFRNHVCITFELLSM-----NLYEL
|......|.||||.| |..... .   |.|... ... . . |.     |..|. .|.        ||. ..| |. ..|... .|.. .      |...
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLN------HPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDY

IK---KNKFQGFSLALVRKFAHSILQCLDSLYRNRIIHCDLKPENILLKQPGRSG--IKVIDFGSSC---YEYQRVYTYIQSRFYRAPEVIL-GGKYGMS
|.   ...|  ||   .....  ||. |. .....|||.||||||||... |  .  .|..|||...   | ..  .|.  ...|.|||||. | .|| .
ISTWRHGCFY-FSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDYNNS-MTTFCGTPWYMAPEVIRGGQYYGPK

IDMWSFGCILAELLTGYPLFPGE----DEGDQLACMMEVLGLPSQKMIESTKRGRTFFSSKGHPRYTTVNINPDGTASYTGGRSRRGKFRGPPGTKDMSR
.||||.||||.|.|.|.|.|||.    .  ||.... ...| |    .. . ....||  .  .                                   .
VDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H---------------------------------F

ALKGCDD---PQFLDFLRHCLEWDPAIRMTPPQALRHPWL
 ..   .   . ..||.. ||..||. | |..|.| |||.
-HWTF-HNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase AqueK113.AA CDK 219-532 25 9.3e-60 189.79 In-house 1-284 (284) Show / Hide 
Range on Protein: 219-532
Range on HMM: 1-284/284
Sequence Identity: 25% (89 aa)

YEVLKVLGKGSFGQVLKAYDHKMQ-----THIALKVVRNEK--------RFHRQAQEEVKILEHLRRQDKDNAHNIIHMIDHFTFR-----------NHV
|| |. .| |..|.| || |.. .       .||| .| |.         |   |  |...| .|        .||.  .| ..             | .
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL-------HPNIVKLHDVCHTKNMDRNNKDKHENKL

CITFELLSMNLYELIKKNKFQGFSLALVRKFAHSILQCLDSLYRNRIIHCDLKPENILLKQPG---RSGIKVIDFGSSCYEY--------QRVYT-YIQS
 . || . . |.....           .. . . .|. |. . .|.|.| |||| |||.   |   .  .|. ||| ..           .|.||  .  
YMVFEYMDHDLKKYMD-----------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMSEPNRTYTHEVVT

RFYRAPEVILGGK-YG--MSIDMWSFGCILAELLT---GYPLFPGEDEGDQLACMMEVLGLPSQKMIESTKRGRTFFSSKGHPRYTTVNINPDGTASYTG
. |||||. || | |.   .|||||.|||.||..|   . |||||. | ||| .  ...| |. ..  . .    .                        
LWYRAPELLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPTEDNWPGVTKLPDY------------------------

GRSRRGKFRGPPGTKDMSRALKGCDDPQFLDFLRHCLEWDPAIRMTPPQALRHPWL
                              |.| ..|  ||. |..  ||| ||..
------------------------------DLLNKMLCYDPKKRISAEQALQHPYF
Kinase AqueK113.AA DyrkP 219-419 40 3.2e-56 183.36 In-house 1-205 (323) Show / Hide 
Range on Protein: 219-419
Range on HMM: 1-205/323
Sequence Identity: 40% (83 aa)

YEVLKVLGKGSFGQVLKAYDHKMQTHIALKVVRNEKRFHRQAQEEVKILEHLRRQDKDNAHNIIHMIDHFTFRNHVCITFELLSMNLYELIKKNK----F
| ..  ||   | . ..  | .    . .|.. | | .  |. .|.|.|  .         |.... | |  . |. |  |||  ||||  | |.     
YQIMEYLGSAAFSKAIQCQDKQTNQMMCMKIIENNKDYFDQSIDEIKLLRYINYNGDVDEKNVLRYYDYFYHKEHLFIITELLKDNLYEFYKFNRENEQQ

QGFSLALVRKFAHSILQCLDSLYRNRIIHCDLKPENILLKQPGRSGIKVIDFGSSCYEYQRVYTYIQSRFYRAPEVILGGKYGMSIDMWSFGCILAELLT
. | .  . |    ||  || .   |.|||||||||||.|   .  .|.|||||||.    .  |.||| |||||||.| ||   ||||| ||||||| |
RYFTVGRLQKITQQILIALDYIHSLRLIHCDLKPENILMKSYPKCQVKIIDFGSSCFIHDHLSSYVQSRSYRAPEVIIGCKYDYRIDMWSLGCILAELWT

GYPLF
|  ||
GNVLF
Kinase AqueK113.AA PRP4 219-443 37 2.5e-55 190.15 In-house 1-229 (320) Show / Hide 
Range on Protein: 219-443
Range on HMM: 1-229/320
Sequence Identity: 37% (87 aa)

YEVLKVLGKGSFGQVLKAY-DHKMQTHIALKVVRNEKRFHRQAQEEVKILEHLRRQ--DKDNAHNIIHMIDHFTFRNHVCITFELLSMNLYELIKKN-KF
|.|    |.| |. | ..    . .  .| |..||    |.    |. ||  |  .  ||.    .. | .|| .|.| |. || .|||| |..||  | 
YRVYGYCGQGVFSNVCRCRDQTRGNEMVAIKIIRNNEIMHKTGLRELEILQKLNDAPTDKNDKFHCVRMFRHFNHRQHMCLVFECMSMNLREVLKKYGKD

QGFSLALVRKFAHSILQCLDSLYRNRIIHCDLKPENILLKQPGRSGIKVIDFGS-SCYEYQRVYTYIQSRFYRAPEVILGGKYGMSIDMWSFGCILAELL
 |..|  || .|  ..  |  | .. |.| |.|| |||     .. .| .|||| |  . . .  | .||||||||.|.| .|  .||||| || |.|| 
VGLHLKAVRSYAQQLFLALKHLKKCNILHADIKPDNILVNE-SKNTLKMCDFGSASHIHENEITPYLVSRFYRAPEIIIGHPYDYQIDMWSVGCTLYELY

TGYPLFPGEDEGDQLACMMEVLGLPSQKMI
||  .|||    . |  .|.. |  ..|||
TGKIMFPGKTNNHMLKLFMDYKGKMPNKMI
Kinase AqueK113.AA CLK 219-353 29 1.5e-51 152.45 In-house 1-147 (350) Show / Hide 
Range on Protein: 219-353
Range on HMM: 1-147/350
Sequence Identity: 29% (44 aa)

YEVLKVLGKGSFGQVLKAYDHKM-QTHIALKVVRNEKRFHRQAQEEVK-ILEHLRRQ-DKDNAHN--IIHMIDHFTF-RNHVCITFELLSMNLYELIKKN
||....|| | || |..  |||.  ...|||..|| ...  .|. |.. |....    |..| .   ...|.| | .  .|.|| |||.  ..|...|.|
YEIVCTLGEGTFGKVVECWDHKNGKKYVALKIIRNVEKYREAAWVEINQIMKKINEKHDPNNKYWEHCWKMNDWFDYGHGHICIVFELYGLSIYDFMKSN

K------FQGFSLALVRKFAHSILQCLDSLYRNRIIHCDLKPENILL
.      .... .. .|..|. ... . .|  ....| |||||||..
NSKMPNKYIPYPIDHIRHMAYQLCEAVKFLHDMKLTHTDLKPENICF
Kinase AqueK113.AA CLK 361-446 44 9.5e-29 82.73 In-house 186-275 (350) Show / Hide 
Range on Protein: 361-446
Range on HMM: 186-275/350
Sequence Identity: 44% (40 aa)

IKVIDFGSSC---YEYQRVYTYIQSRFYRAPEVILGGKYGMSIDMWSFGCILAELLTGYPLFPGEDEGDQLACMMEVLGLPSQ-KMIEST
|.||||||     ...   .| ...| |||||||||  .    | ||.|||| || ||. ||.. |. . || | ...|.| .  || .|
ICVIDFGSATKIRFDHEHHSTIVSTRHYRAPEVILGLGWSQPCDVWSIGCILFELYTGFTLFQTHDNREHLAMMERIMGMPIPQWMIQRT
Kinase AqueK113.AA TyrKc 219-536 16 1e-10 -49.42 SMART 1-280 (280) Show / Hide 
Range on Protein: 219-536
Range on HMM: 1-280/280
Sequence Identity: 16% (59 aa)

YEVLKVLGKGSFGQVLKAYDHKMQTHIALKVVRNEKRFHRQAQEEVKILEHL-RRQDKDNAHNIIHMIDHFTFR-------NHVCITFELLSM-NLYELI
 . .|.|| | ||.| |.      .  | |......  ..   .| .|. .|       .  ||. ..   |           ..| .|. .  .| . .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA--REDFMREARIMCKLGG-----HHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYL

KKNKFQGFSLALVRKFAHSILQCLDSLYRNRIIHCDLKPENILLKQPGRSGIKVIDFGSSCYEYQR-------VYTYI----QSR-----FYRAPEVILG
.|.. . ....   .|.. | .  . | ....|| ||   |.|.. ..   .|. ||| | . |          |       ...        |||.|  
RKHRPK-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH--TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINY

GKYGMSIDMWSFGCILAELLT-GYPLFPGE----DEGDQLACMMEVLGLPSQKMI----ESTKRGRTFFSSKGHPRYTTVNINPDGTASYTGGRSRRGKF
||.    | ||||  . |..| | .  ||.     . ...    .  . . |                                                
GKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS----------------------------------------

RGPPGTKDMSRALKGCDDPQFLDFLRHCLEWDPAIRMTPPQALRHPWLRRRL
         .     |  .   .  . | . ||. | |  .       ....
---------F----VCCPDEMYQIMKQCWHEDPEDRPTFSEI------HECF
Kinase AqueK113.AA CLK 504-532 44 2.8e-09 23.23 In-house 322-350 (350) Show / Hide 
Range on Protein: 504-532
Range on HMM: 322-350/350
Sequence Identity: 44% (13 aa)

QFLDFLRHCLEWDPAIRMTPPQALRHPWL
|. | .| .|| ||. |.| ..|| ||. 
QLFDLIRKMLEYDPSKRITCKDALQHPFF
Kinase AqueK113.AA PRP4 504-532 48 8e-08 24.8 In-house 292-320 (320) Show / Hide 
Range on Protein: 504-532
Range on HMM: 292-320/320
Sequence Identity: 48% (14 aa)

QFLDFLRHCLEWDPAIRMTPPQALRHPWL
|| |.|  ||  ||. | |. .||.|| .
QFKDLLDKCLMLDPKKRITCNEALKHPFI
Kinase AqueK113.AA DyrkP 501-532 50 2e-07 19.79 In-house 292-323 (323) Show / Hide 
Range on Protein: 501-532
Range on HMM: 292-323/323
Sequence Identity: 50% (16 aa)

DDPQFLDFLRHCLEWDPAIRMTPPQALRHPWL
||  |.|| | ||  |   | |   ||.|||.
DDHMFIDFVRQCLQIDFTRRPTAKEALQHPWF
Kinase AqueK113.AA YAK 505-532 39 7e-06 15.47 In-house 320-347 (347) Show / Hide 
Range on Protein: 505-532
Range on HMM: 320-347/347
Sequence Identity: 39% (11 aa)

FLDFLRHCLEWDPAIRMTPPQALRHPWL
|.||.   |. .|  | .| ||  || .
FIDFINQLLQLNPRERWKPMQAMQHPFI
Kinase AqueK113.AA HIPK 501-532 37 0.000131 9.89 In-house 298-329 (329) Show / Hide 
Range on Protein: 501-532
Range on HMM: 298-329/329
Sequence Identity: 37% (12 aa)

DDPQFLDFLRHCLEWDPAIRMTPPQALRHPWL
|  .| . |.  . ||.  |.|| .||.||. 
DRREFVHVLKKMCTWDAHKRITPCEALNHPFV