Gene AqueK128 (A.queenslandica)

AqueK128

Species: A.queenslandica
Alias: AqueK128
External Links:
Annotation:

Classification

Group: CMGC
Family: MAPK
Subfamily: nmo

Sequence

Name Sequence Type Origin Length Description Download
AqueK128.AA Protein None 395 None Fasta, JSON
AqueK128.kin_dom Protein Kinase Domain None 291 None Fasta, JSON

Protein domain

Protein domains of AqueK128.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase AqueK128.AA nmo 12-302 55 2.3e-157 487.96 In-house 1-292 (292) Show / Hide 
Range on Protein: 12-302
Range on HMM: 1-292/292
Sequence Identity: 55% (164 aa)

VELSHPIGYGSFGVVWSVKNPRTGGLSALKRIPRVFQSLLSCVRTFREIKMLCELKHDNILSAIDFIKPDNMEEFSDIYVLTDLMETDLHHIIISPQPLT
..   ||||| |||||||  || |   |||..| |||.|.|| | |||.||||  ||||.||| | ..| ... | .|||.|.||  ||| ||.|||.|.
IQPDRPIGYGAFGVVWSVTDPRDGKRVALKKMPNVFQNLVSCKRVFRELKMLCFFKHDNVLSALDILQPPHKDFFQEIYVVTELMQSDLHKIIVSPQHLS

EDHIKLFLYQLLRGVKYLHSAGIIHRDLKPGNLLVNSTCLLRICDFGFARAVEVNPRTPMTLEVVTQYYRAPELLAGCQQYGPAIDMWAIGCIVGELLGR
 ||.| ||||.|||.||||||.|.|||.||||||||| |.|.||||| ||  | . .  || |||||||||||.| | ..|  |.|.|..||| .|||||
SDHVKVFLYQILRGLKYLHSANILHRDIKPGNLLVNSNCVLKICDFGLARVWEQDQSKHMTQEVVTQYYRAPEILMGARHYTSAVDIWSVGCIFAELLGR

KILFKGSDADSQLDLILELLGTPSAPDISHISSPVSRKRLLSVTRPNTMQEVLYQLSP--NASHGVVHLLSRMLVFNPYKRISCHDSLSHPYI
.|||.      ||..| .||||||  |. .      .  .|  .  .   .|||.||   .| |  ||||.|||.|.| |||||.| | |||.
RILFQAQSPIQQLQMITDLLGTPSMEDMKYACE-GAKAHMLRMPHKPPCLQVLYTLSSPDHATHEAVHLLCRMLHFDPDKRISCKDALAHPYL
Kinase AqueK128.AA MAPK 12-302 42 4.7e-142 478.24 In-house 1-328 (328) Show / Hide 
Range on Protein: 12-302
Range on HMM: 1-328/328
Sequence Identity: 42% (139 aa)

VELSHPIGYGSFGVVWSVKNPRTGGL--S----ALKRIPRVFQSLLSCVRTFREIKMLCEL-KHDNILSAIDFIKP------DNMEEFSDIYVLTDLMET
 ..  |||.|..|||.|..  ||..   .    |.|.|.|.||....| ||.||||.|... .|.|| . .| ..|      ...||| |||. ..||||
YQILKPIGQGAYGVVCSAIDKRTNQKTKCGKKVAIKKISRPFQNPTHCKRTYREIKLLRHFHHHENIIKLLDIFTPEMQDDQNSLEEFNDIYIVMELMET

DLHHIIISPQPLTEDHIKLFLYQLLRG--VKYLHSAGIIHRDLKPGNLLVNSTCLLRICDFGFARAVEVNPRTP-------------MTLEVVTQYYRAP
|||.|| |.|||..|||. |.||.|||  .||.|||..|||||||.|.|||. |.|.||||| || .. .   .             ||  |.|..||||
DLHQIIKSQQPLSDDHIQYFMYQILRGLKLKYIHSANVIHRDLKPSNILVNENCDLKICDFGLARSIDPEYHHHHQQDDPHCFQKMHMTEYVATRWYRAP

ELLAG--CQQYGPAIDMWAIGCIVGELLG-RKILFKGSDADSQLDLILELLGTPSAPDISHIS-SPVSRKRLLSVT-RPNTMQEVLYQLSPN----ASHG
|.. .   . |  |.|||..||| .|.|. ||.||.|.|   |. ||.|.|||||  .|. |. |.  |. . |    |.. .  .... ||    |.. 
EIMLNWIWMHYTKAVDMWSVGCIFAEMLTDRKPLFPGKDYIDQWNLIMEVLGTPSEEFIQCICMSEHARNYIQSLGNLPKYPKKPWEKMFPNANFNANPQ

VVHLLSRMLVFNPYKRISCHDSLSHPYI
 ..||..||||.| |||.  . |.|||.
AIDLLEKMLVFDPDKRITVEEALQHPYF
Kinase AqueK128.AA CMGC 12-302 22 5.6e-116 382.81 In-house 1-513 (513) Show / Hide 
Range on Protein: 12-302
Range on HMM: 1-513/513
Sequence Identity: 22% (116 aa)

VELSHPIGYGSFGVVWSVKNPRTG--------------GLSALKRIPRVFQSLLSCV----------RTFREIKMLCELK-----------------HDN
 |   .|| |..|||.. .. ||.               . |.|.| ..|     .           |..||||.| .|.                 | |
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

ILSAIDFIKPDN-------------MEEFSDIYVLTDLMETDLHHIIISPQ---------PLTEDH------------IKLFL------YQLLRGVK--Y
|.. .|.....|               .| ..|  ...|..||...| . |         ||.| |            || |.      ||.|||.|  |
IVKLYDIFYHKNSDGNEYEDKHIISQ-HFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKY

LHSAG--IIHRDLKPGNLLVNSTCLL--------------------RICDFGFARAVEVN--------------------PRTPMTLEVVTQYYRAPELL
.||..  |||||||| |.|.|..| |                    .|||||.||.....                    |. |.| .||| .|||||.|
CHSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEIL

AGC---------QQYGPAIDMWAIGCIVGELLGR--------KILFKGSDA-----------DSQLDLILELLGTPS---------------APDISHIS
 |.         ..|...||||..||| .|.. .        |.||.|..              ||..| ..||||.                 ..  ..
LGWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMI

S--------------------PVSRKRLLSV--TRPNTMQEVLYQLSPN-----------------------------------ASHGVVHLLSRMLVFN
.                    . . .. ..   . |.     . .| |.                                   ...  ..||..||...
KLPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYD

PYKRISCHDSLSHPYI
| |||.. . |.|||.
PDKRITAEQALQHPYF
Kinase AqueK128.AA ERK 13-302 42 4e-109 368.83 In-house 2-307 (307) Show / Hide 
Range on Protein: 13-302
Range on HMM: 2-307/307
Sequence Identity: 42% (131 aa)

ELSHPIGYGSFGVVWSVKNPR-----TGGLSALKRIPRVFQSLLSCVRTFREIKMLCELK-HDNILSAIDFIKPDNMEEFSDIYVLTDLMETDLHHIIIS
..  .||.|..||| |...       ||   | | |...|  .. | || ||||.|  .| |.|| . .| ..|.  |.. |||. ..||||||| || |
QIIKQIGHGAYGVVCSAIDKEYCFDETGQKVAIKKIENAFDHPIYCKRTLREIKLLRHFKGHENIICLFDIMMPNSPEQYNDIYCVEELMETDLHQIINS

PQPLTEDHIKLFLYQLLRGVKYLHSAGIIHRDLKPGNLLVNSTCLLRICDFGFAR----AVEVNPRT---PMTLEVVTQYYRAPELLAGCQQYGPAIDMW
.|.|..||.. |.||.|.|.||.|||..|||||||.|.|||| | | |||||.||     .. |. .    ||  |.| .|||||..   | |  |.|.|
QQELSDDHCQYFMYQILCGLKYIHSANVIHRDLKPSNILVNSNCDLKICDFGLARCFDASYQENHECNQNFMTEYVATRWYRAPEIMLSWQKYTKAMDIW

AIGCIVGELLGRKILFKGSDADSQLDLILELLGTP-SAPDISHISSPVSRKRLLSVTRPNTMQEVLYQLSPNAS--HGVVHLLSRMLVFNPYKRISCHDS
..|||  |.|||| ||.| | . |...|....||| |  |.. | |.  .| . .   |    . .. . |||.  .  . ||..||||.| |||.  . 
SCGCIFAEMLGRKPLFPGKDYVHQINRIFQIIGTPHSEEDLQYICSENAWKYIKNLPNPVRPPKPWENIFPNANCNPQAIDLLEKMLVFDPDKRITVEEC

LSHPYI
|.||| 
LEHPYF
Kinase AqueK128.AA ERK5 13-302 41 7.1e-96 324.83 In-house 2-295 (295) Show / Hide 
Range on Protein: 13-302
Range on HMM: 2-295/295
Sequence Identity: 41% (123 aa)

ELSHPIGYGSFGVVWSVKNPRTGGLSALKRIPRVFQSLLSCVRTFREIKMLCELKHDNILSAIDFIKPDN-MEEFSDIYVLTDLMETDLHHIIISPQPLT
.    || | .||| | .. ..|   |.|.||  |  .    |||||.|.|   .||||.   | ..|   . |. |.||  |||| ||| || | ||.|
KIIEKIGNGAYGVVCSARRRKNGQQVAIKKIPNAFDVVTNAKRTFRELKILRHFRHDNIIAIRDILMPKVPYSEMKDVYVVFDLMESDLHQIIHSNQPFT

EDHIKLFLYQLLRGVKYLHSAGIIHRDLKPGNLLVNSTCLLRICDFGFARAVEV----NPRTPMTLEVVTQYYRAPELLAGCQQYGPAIDMWAIGCIVGE
 .||. ||||.|||.||.||| .||||||| |||||  | |.| ||| || .      . .  ||  | | .||||||.   ..|  |||.|..|||.||
LEHIRYFLYQILRGLKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTFSPDKHQMFMTEYVATRWYRAPELMFSSHDYTQAIDVWSVGCIFGE

LLGRKILFKGSDADSQLDLILELLGTPSAPDISHISSPVSRKRLLSVTRPNTMQEVLYQLSPNASHGVVHLLSRMLVFNPYKRISCHDSLSHPYI
...|. .| |     ||.||.. ||.|..  |  .|.   .  . .   . . .. . .. | |    . ||.|||.| | .||.    | ||..
MIARRQMFPGKNYIHQLQLIMMVLGMPPPHMIQAVSADHVYNYFQKNFPNRQPKD-WEKVYPKADRQALDLLARMLRFEPSERITVNKALQHPFL
Kinase AqueK128.AA p38 12-302 37 1.6e-95 323.69 In-house 1-289 (289) Show / Hide 
Range on Protein: 12-302
Range on HMM: 1-289/289
Sequence Identity: 37% (113 aa)

VELSHPIGYGSFGVVWSVKNPRTGGL---SALKRIPRVFQSLLSCVRTFREIKMLCELKHDNILSAIDFIKP--DNMEEFSDIYVLTDLMETDLHHIIIS
 .   |.| |..| | ..   |||.     | |.. | ||| .   ||.||.. |  ..|.|.....|   |  ..|..|.|.|. | .|..||. |. .
YQNLQPVGSGAYGQVCKAEDRRTGQKRRYVAIKKLMRPFQSEIHAKRTYRELRLLKHMRHENVICLLDVFTPPAHSMNDFQDVYMVTHFMGADLNNIMKC

PQPLTEDHIKLFLYQLLRGVKYLHSAGIIHRDLKPGNLLVNSTCLLRICDFGFARAVEVNPRTPMTLEVVTQYYRAPELLAGCQQYGPAIDMWAIGCIVG
 | |..|||.. .||.||| || ||||||||||||.|. ||  | ||| ||| ||. .    . ||  |.|  ||||| .    .|  ..|.| .|||  
-QRLSDDHIQFLVYQILRGLKYIHSAGIIHRDLKPSNIAVNEDCELRILDFGLARHCD----DEMTGYVATRWYRAPEIMLNWMHYTQTVDIWSVGCIMA

ELLGRKILFKGSDADSQLDLILELLGTPSAPDISHISSPVSRKRLLSVTRPNTM--QEVLYQLSPNASHGVVHLLSRMLVFNPYKRISCHDSLSHPYI
||. ...||.|.|  .||  |....|||..  .. |.|  .|  . | .    .  ..|. . .| |    . || .||.  | |||.  . ..|||.
ELITGRTLFPGDDHIDQLQRIMKVCGTPDEEFWQKIQSEEARNYIQSYPQMPRRDFHHVFMGANPQA----IDLLEKMLELDPDKRITAEEAMQHPYF
Kinase AqueK128.AA ERK7 13-302 40 1.4e-93 317.18 In-house 2-292 (292) Show / Hide 
Range on Protein: 13-302
Range on HMM: 2-292/292
Sequence Identity: 40% (119 aa)

ELSHPIGYGSFGVVWSVKNPRTGGLSALKRIPRVFQSLLSCVRTFREIKMLCELK-HDNILSAIDFIKPDNMEEFSDIYVLTDLMETDLHHIIISPQPLT
|. . .| | .|.|| .   ||.   |||.|   |.      |||||| .| |.. |.||.. |. |. ||     |||.  . |||||| .|   . | 
EIRKRLGKGAYGIVWKAYDKRTKQVVALKKIFDAFRNQTDAQRTFREIMFLQEFHCHPNIIRLINVIRADNDR---DIYLVFEFMETDLHAVIRKGNILK

EDHIKLFLYQLLRGVKYLHSAGIIHRDLKPGNLLVNSTCLLRICDFGFARAVEVNP----RTPMTLE-VVTQYYRAPELLAGCQQYGPAIDMWAIGCIVG
. | .  .||||| .||.||. .||||||| |.|..| |....|||| || .   .     .||  | | |  ||||| | | ..| ...||| ||||.|
DIHKQYIMYQLLRAIKYMHSGNVIHRDLKPSNILLDSECMVKVCDFGLARSIAQQEEYDEQNPMLTEYVATRWYRAPEILLGSHRYTKGVDMWSIGCILG

ELLGRKILFKGSDADSQLDLILELLGTPSAPDISHISSPVSRKRLLSVTRPNTMQEVLYQLSPNASHGVVHLLSRMLVFNPYKRISCHDSLSHPYI
|.|  | .| |.    |...|||... |.. ||  | | .. . | ..    . .. | |. |....  . || |.||||| ||..  . |.|||.
EMLRGKPMFPGTSTMNQIEKILETIPKPTQEDIEAIGSHYAWNMLEQMN--QQKRKTLDQMMPQCCDDAIDLLKRLLVFNPKKRLTAEQALQHPYV
Kinase AqueK128.AA S_TKc 12-302 24 4.4e-85 289.88 SMART 1-231 (231) Show / Hide 
Range on Protein: 12-302
Range on HMM: 1-231/231
Sequence Identity: 24% (76 aa)

VELSHPIGYGSFGVVWSVKNPRTGGLSALKRIPRVFQSLLSCVRTFREIKMLCELKHDNILSAIDFIKPDNMEEFSDIYVLTDLMET---DLHHIIISPQ
 |.  .|| |.||.|. ... .|| . |.|.|.          .. |||..| . .|.||   .|..        ...|. ......   ||...| . .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD------DHLYMVMEYCDGDLGDLFDYIKKRG

P------LTEDHIKLFLYQLLRGVKYLHSAGIIHRDLKPGNLLVNSTCLLRICDFGFARAVEVNPRTPMTLEVVTQYYRAPELLAGCQQYGP-AIDMWAI
.      ..| |.. ..||......|.|| ||||||||| |.|...   . |||||.|| .        |  ..| .|.|||.|    .||. ..|.|..
RHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL----GYGKCKCDWWSC

GCIVGELLGRKILFKGSDADSQLDLILELLGTPSAPDISHISSPVSRKRLLSVTRPNTMQEVLYQLSPNASHGVVHLLSRMLVFNPYKRISCHDSLS---
|||. |.| .. .|       |........|                                       |. . ......|...| ||... . |    
GCILYEMLCGYPPFP------QMQMMFKKIG---------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEW

----HPYI
    ||..
DIKCHPWF
Kinase AqueK128.AA ERK1 12-302 41 2.3e-82 279.94 In-house 2-289 (289) Show / Hide 
Range on Protein: 12-302
Range on HMM: 2-289/289
Sequence Identity: 41% (123 aa)

VELSHPIGYGSFGVVWSVKNPRTGGLSALKRIPRVFQSLLSCVRTFREIKMLCELKHDNILSAIDFIKPDNMEEFSDIYVLTDLMETDLHHIIISPQPLT
..|.  || | .|.| |    ...   |.|.|   |     | || ||||.|   ||.||.   | |. | .|.. |.|.  .||||||  .. . |.| 
TNLQY-IGEGAYGMVCSAYDTVHKQRVAIKKI-SPFEHQTYCQRTLREIKILTRFKHENIINIQDIIRADTIEQMRDVYIVQCLMETDLYKLLKT-QHLS

EDHIKLFLYQLLRGVKYLHSAGIIHRDLKPGNLLVNSTCLLRICDFGFARAV--EVNPRTPMTLEVVTQYYRAPELLAGCQQYGPAIDMWAIGCIVGELL
 |||  ||||.|||.||.||| ..|||||| |||.| || |.||||| ||    |      .|  | | .|||||..   . |  .||.|..|||. |.|
NDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEML

GRKILFKGSDADSQLDLILELLGTPSAPDISHISSPVSRKRLLSVTRPNTMQEVLYQLSPNASHGVVHLLSRMLVFNPYKRISCHDSLSHPYI
  . .| |     || .|| .|| ||  |.  |     |  | |.  |   .  . .| |.|    . || .|| ||| |||   . | |||.
SNRPIFPGKHYLDQLNHILGVLGSPSQDDLNCIINEKARNYLQSL--PHKPKVPWARLFPKADSKALDLLDKMLTFNPHKRITVEEALAHPYL
Kinase AqueK128.AA CDK 58-302 34 1.5e-81 260.62 In-house 57-284 (284) Show / Hide 
Range on Protein: 58-302
Range on HMM: 57-284/284
Sequence Identity: 34% (92 aa)

REIKMLCELKHDNILSAIDFIKPDNME----EF--SDIYVLTDLMETDLHHIIISPQPLTEDHIKLFLYQLLRGVKYLHSAGIIHRDLKPGNLLVNSTCL
|||..| || |.|| . .| .  .||.     .  . .|   . |..|| ...          || ...|||||. |.|| .|.|||||| |.|.|..  
REISLLKEL-HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFEYMDHDLKKYMD---------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGE

-----LRICDFGFARAVEVN-----PRTPMTLEVVTQYYRAPELLAGCQQYG--PAIDMWAIGCIVGELLG---RKILFKGSDADSQLDLILELLGTPSA
     | | |||.|||  ..     |. ..| ||||  ||||||| |...|.  ..||||..||| .|..    || || |.    ||..| ...|||. 
VKCGRLKIADFGLARAFGIPHQMSEPNRTYTHEVVTLWYRAPELLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPTE

---PDISHISSPVSRKRLLSVTRPNTMQEVLYQLSPNASHGVVHLLSRMLVFNPYKRISCHDSLSHPYI
   |....                                   .||..||...|.||||. . |.||| 
DNWPGVTKLPDY-------------------------------DLLNKMLCYDPKKRISAEQALQHPYF
Kinase AqueK128.AA Pkinase 12-302 29 9.7e-79 272.7 Pfam 1-293 (293) Show / Hide 
Range on Protein: 12-302
Range on HMM: 1-293/293
Sequence Identity: 29% (90 aa)

VELSHPIGYGSFGVVWSVKNPRTGGLSALKRIPRVFQSLLSCVRTFR--EIKMLCELKHDNILSAIDFIKPDNMEEFSDIYVLTDLMET-----DLHHII
 ..  .|| ||||.|.  ..  || . |.|.|... ..   ... .|  ||... .|.|.||.  .|.         ..||. ....|      ||...|
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED-----KDHIYMVMEYCEGGLYVMDLFDYI

I--SPQPL--TEDHIKLFLYQLLRGVKYLHSAGIIHRDLKPGNLLVNSTCLL----RICDFGFARAVEVNPRTPMTLEVVTQYYRAPELLAGCQQYGPAI
   .  ..  .|...| ..||.|||..|.|| ||||||||| |.|..... .    .|||||.|. ..  . . ||  ..| .|.|||.. |.| |||..
STWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKV

DMWAIGCIVGELLGRKILFKGS----DADSQLDLILELLGTPSAPDISHISSPVSRKRLLSVTRPNTMQEVLYQLSPNASHGVVHLLSRMLVFNPYKRIS
|||..|||. |.| .. .|.|.    . ..|. .| . .|.|   |..  .|.  .. .   . .    . .  . .|.|    ......| ..|.||..
DMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H----F-HWTF-HNWSEECKDFIKWCLCKDPKKRPT

CHDSLSHPYI
... | ||..
AEQILQHPWF
Kinase AqueK128.AA MAPK-Unclassified 13-166 43 2.7e-60 206.65 In-house 2-162 (575) Show / Hide 
Range on Protein: 13-166
Range on HMM: 2-162/575
Sequence Identity: 43% (70 aa)

ELSHPIGYGSFGVVWSVKNPRT-GGLSALKRIPRVFQSLLSCVRTFREIKMLCELKHDNILSAIDFIKPDNMEE--FSDIYVLTDLMET---DLHHIIIS
|..  || |..|.|   .  .. .   | |.....|.    | |. |||  | .| | ||.   | . ..  .   | |||. .|.|.|   |||.|| |
EYQKNIGSGAYGQVCRAMDKKNQNQQVAIKKVNHIFHNHTDCKRVLREIRILRYLNHPNIIQIQDIFYNKELHNQEFDDIYIVMDYMQTSLFDLHQIIKS

PQ-PLTEDHIKLFLYQLLRGVKYLHSAGIIHRDLKPGNLLVNSTCLLRICDFGFARAVEVN
.| .. . ||. |.||.||| ||||||.|||||||| |||.|  |..|||||| .| .| |
NQDHWCHQHIQYFFYQILRGLKYLHSACIIHRDLKPSNLLINQDCSVRICDFGMSRSIEDN
Kinase AqueK128.AA MAPK-Unclassified 171-302 26 6.9e-30 104.99 In-house 405-575 (575) Show / Hide 
Range on Protein: 171-302
Range on HMM: 405-575/575
Sequence Identity: 26% (45 aa)

MTLEVVTQYYRAPELLAGCQQYGPAIDMWAIGCIVGELLGR-----------KILFKGSD--------------------ADSQLDLILELLGTPSAPDI
||  ||| .|||||..   . |. ..|.|.|||| .|.. .           ..||.|.|                      .|. .|.. ||.|   |.
MTQYVVTRWYRAPEIMLSMHEYDTQVDIWSIGCIFAEMMQMYDRHNPTFSDHRPLFPGQDCFPITPDRNNDVDQGGFPHSHQDQIKMIFDYLGMPPEEDC

SHISSPVSRKRLLSVTRPNTMQEVLYQLSPNAS---------HGVVHLLSRMLVFNPYKRISCHDSLSHPYI
. | ..  || . |  . . . ..     ..|.              ... ||.||| |||.  . |.|||.
NFITCDSARKYIQSFKCKTPV-HFTDLMFCKAPGDDQIVRGNCECIDFVQKMLQFNPWKRITADQALEHPYF
Kinase AqueK128.AA TyrKc 12-297 16 2.4e-11 -39.08 SMART 1-280 (280) Show / Hide 
Range on Protein: 12-297
Range on HMM: 1-280/280
Sequence Identity: 16% (54 aa)

VELSHPIGYGSFGVVWS--------VKNPRTGGLSALKRIPRVFQSLLSCVRTFREIKMLCEL--KHDNILSAIDFIKPD--NMEEF---SDIYVLTDLM
..| . .| | ||.|.         ||  . .                      ||....|.|  .|.||.  .  .  .  |   |     ..... .|
ITLGKKLGEGAFGEVYKGTWKIQVAVKMLKEDA----------------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRN---FMYIEPLMIVMEYM

ET-DLHHIIISPQP-LTEDHIKLFLYQLLRGVKYLHSAGIIHRDLKPGNLLVNSTCLLRICDFGFARAVEVN-------PRTPM----TLE-VVTQYYRA
.  ||.. . ...| |. ..   | .|  .|  |||| ..|||||   | ||..    .|.||| .|...             .        ..     |
PHGDLKDYLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMA

PELLAGCQQ-YGPAIDMWAIGCIVGELLGRKILFKGS-----DADSQLDLILELLGTPSAPDI----SHISSPVSRKRLLSVTRPNTMQEVLYQLSPNAS
|| .      . .. | |. |    |.. .              ....   ..  . .  |.     |                           .. ..
PECI--NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS---------------------------FVCCP

HGVVHLLSRMLVFNPYKRIS---CHDSL
  .  . ..   ..| .| .   .|. .
DEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase AqueK128.AA Pkinase_Tyr 57-163 31 1e-06 22.93 Pfam 51-161 (270) Show / Hide 
Range on Protein: 57-163
Range on HMM: 51-161/270
Sequence Identity: 31% (36 aa)

FREIKMLCEL-KHDNILSAIDFIKPDNMEEFSD--IYVLTDLMET-DLHHIIIS----PQPLTEDHIKLFLYQLLRGVKYLHSAGIIHRDLKPGNLLVNS
.||.|....| .|.||.. .  .     ..     ||. . .|.  ||..   .    .||||  ..  . .|  .|  ||.| ..|||||   | ||..
MREAKIMKQLGHHPNIVRLYGVCT----DQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTE

TCLLRICDFGFARAV
.   .||||| ||..
NNVVKICDFGLARDI
Kinase AqueK128.AA Pkinase_Tyr 12-27 31 0.020802 8.78 Pfam 1-16 (270) Show / Hide 
Range on Protein: 12-27
Range on HMM: 1-16/270
Sequence Identity: 31% (5 aa)

VELSHPIGYGSFGVVW
... . .| |.||.|.
ITFGKKLGEGAFGEVY