Gene AqueK131 (A.queenslandica)

AqueK131

Species: A.queenslandica
Alias: AqueK131
External Links:
Annotation:

Classification

Group: CMGC
Family: MAPK
Subfamily: p38

Sequence

Name Sequence Type Origin Length Description Download
AqueK131.AA Protein None 364 None Fasta, JSON
AqueK131.kin_dom Protein Kinase Domain None 289 None Fasta, JSON

Protein domain

Protein domains of AqueK131.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase AqueK131.AA p38 25-313 55 2.6e-169 568.77 In-house 1-289 (289) Show / Hide 
Range on Protein: 25-313
Range on HMM: 1-289/289
Sequence Identity: 55% (163 aa)

YQELTPINSGAYGQVCSALDTKYGIR---VAIKKLYAPFEHRHNAKKAYREMRILSHLKHENCIGLLDVFSP-CEDIEEFSDFYMVMHLMSMDLAKLLKE
||.|.|. ||||||||.| |.. | .   ||||||. ||.  . || .|||.| | |..||| |.||||| |  .....|.|.|||.|.|  || ...| 
YQNLQPVGSGAYGQVCKAEDRRTGQKRRYVAIKKLMRPFQSEIHAKRTYRELRLLKHMRHENVICLLDVFTPPAHSMNDFQDVYMVTHFMGADLNNIMKC

NRTSQILSEDHIKFLLYQILCGLKYVHSAGIIHRDLKPSNIAVNPTCDLRILDFGLARQTDRDMTGYVSTRHYRAPEIMLSWENYGKQVDVWSVGCIMAE
 |    ||.|||.||.|||| ||||.||||||||||||||||||  |.||||||||||..| .||||| || ||||||||.|  | . ||.|||||||||
QR----LSDDHIQFLVYQILRGLKYIHSAGIIHRDLKPSNIAVNEDCELRILDFGLARHCDDEMTGYVATRWYRAPEIMLNWMHYTQTVDIWSVGCIMAE

LLGSKVLFPGDNQIDQLHKIFEIMGTPSQSLIDKIPHQKTKLYLQSLKVIKPKNLKNLLEIHNNDALDLLKKLLTLDPERRITVEEALSHPYL
|.  ..|||||. |||| .| ...|||.. .. ||  .. . |.||.  .. .......  .|  |.||| |.| |||..|||.|||..|||.
LITGRTLFPGDDHIDQLQRIMKVCGTPDEEFWQKIQSEEARNYIQSYPQMPRRDFHHVFMGANPQAIDLLEKMLELDPDKRITAEEAMQHPYF
Kinase AqueK131.AA MAPK 25-313 47 3.1e-164 551.91 In-house 1-328 (328) Show / Hide 
Range on Protein: 25-313
Range on HMM: 1-328/328
Sequence Identity: 47% (157 aa)

YQELTPINSGAYGQVCSALDTK------YGIRVAIKKLYAPFEHRHNAKKAYREMRILSHL-KHENCIGLLDVFSPC-----EDIEEFSDFYMVMHLMSM
|| | || .||||.|||| |..      .| .|||||.  ||.. . .| .||| ..| |. .||| |.|||.| |      ...||| |.|.||.||  
YQILKPIGQGAYGVVCSAIDKRTNQKTKCGKKVAIKKISRPFQNPTHCKRTYREIKLLRHFHHHENIIKLLDIFTPEMQDDQNSLEEFNDIYIVMELMET

DLAKLLKENRTSQILSEDHIKFLLYQILCG--LKYVHSAGIIHRDLKPSNIAVNPTCDLRILDFGLARQTDRD-----------------MTGYVSTRHY
|| ...| ..   .||.|||....||||.|  ||| |||..||||||||||.||  |||.|.||||||..| .                 ||.||.|| |
DLHQIIKSQQ---PLSDDHIQYFMYQILRGLKLKYIHSANVIHRDLKPSNILVNENCDLKICDFGLARSIDPEYHHHHQQDDPHCFQKMHMTEYVATRWY

RAPEIMLS--WENYGKQVDVWSVGCIMAELLG-SKVLFPGDNQIDQLHKIFEIMGTPSQSLIDKIP-HQKTKLYLQSL---KVIKPKNLKNLLE----IH
|||||||.  | .| |.||.||||||.||.|.  |.||||.. |||. .|.|..||||. .| .|.  .. . |.|||   .  ..|......     ..
RAPEIMLNWIWMHYTKAVDMWSVGCIFAEMLTDRKPLFPGKDYIDQWNLIMEVLGTPSEEFIQCICMSEHARNYIQSLGNLPKYPKKPWEKMFPNANFNA

NNDALDLLKKLLTLDPERRITVEEALSHPYL
| .|.|||.|.|..||..||||||||.|||.
NPQAIDLLEKMLVFDPDKRITVEEALQHPYF
Kinase AqueK131.AA CMGC 25-313 27 1.5e-135 448.3 In-house 1-513 (513) Show / Hide 
Range on Protein: 25-313
Range on HMM: 1-513/513
Sequence Identity: 27% (140 aa)

YQELTPINSGAYGQVCSALD--------------TKYGIRVAIKKLYAPFEHRHNAK----------KAYREMRILSHLK-----------------HEN
|. . .| .|.||.|... |              .... .|||||.  || . . ||          .|.|| .|| ||.                 |.|
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

CIGLLDVFSP-CEDIEEFS----------DFYMVMHLMSMDLAKLLKENRT------SQILSEDH------------IKFLL------YQILCGLK--YV
...|.|.| .  .| .|..          ..|.|. .| .||....|.|..       . ||| |            ||...      ||||.|||  | 
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYC

HSAG--IIHRDLKPSNIAVNPTCDL--------------------RILDFGLARQTDRD------------------------MTGYVSTRHYRAPEIML
||..  ||||||||.|| .|..|.|                    .| ||||||...                          .| ||.||.||||||.|
HSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILL

SW---------ENYGKQVDVWSVGCIMAELLGS--------KVLFPGDNQ-----------IDQLHKIFEIMGTP----------------SQSLIDKIP
.|          .|....|.||||||.||..          | ||||..            ||||.|||...|||                ..  ...|.
GWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMIK

--------------------HQKTKLYLQS---LKVIKPKNLKNLLEIHNN-----------------------------------DALDLLKKLLTLDP
                      . ..|.||   .. ..||..|||   |.|                                   .|.|||||.|..||
LPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDP

ERRITVEEALSHPYL
..|||.|.||.|||.
DKRITAEQALQHPYF
Kinase AqueK131.AA ERK 25-313 47 1.3e-131 443.53 In-house 1-307 (307) Show / Hide 
Range on Protein: 25-313
Range on HMM: 1-307/307
Sequence Identity: 47% (147 aa)

YQELTPINSGAYGQVCSALDTK-----YGIRVAIKKLYAPFEHRHNAKKAYREMRILSHLK-HENCIGLLDVFSPCEDIEEFSDFYMVMHLMSMDLAKLL
|| . .|  |||| |||| |..      | .|||||   .|.|.  .| ..|| ..| |.| ||| |.|.|.. | . .|.. | |.|  ||  ||..  
YQIIKQIGHGAYGVVCSAIDKEYCFDETGQKVAIKKIENAFDHPIYCKRTLREIKLLRHFKGHENIICLFDIMMP-NSPEQYNDIYCVEELMETDLHQII

KENRTSQILSEDHIKFLLYQILCGLKYVHSAGIIHRDLKPSNIAVNPTCDLRILDFGLARQTDR-----------DMTGYVSTRHYRAPEIMLSWENYGK
.   ..| ||.||.....|||||||||.|||..|||||||||| ||  ||| | ||||||  |            .||.||.|| ||||||||||..| |
N---SQQELSDDHCQYFMYQILCGLKYIHSANVIHRDLKPSNILVNSNCDLKICDFGLARCFDASYQENHECNQNFMTEYVATRWYRAPEIMLSWQKYTK

QVDVWSVGCIMAELLGSKVLFPGDNQIDQLHKIFEIMGTP-SQSLIDKIPHQKTKLYLQSLKV--IKPKNLKNLLEIHN--NDALDLLKKLLTLDPERRI
 .|.||.|||.||.|| | |||| . ..|.  ||.|.||| |.  . .|. .... |. .|    ..||...|.   .|   .|.|||.|.|. ||. ||
AMDIWSCGCIFAEMLGRKPLFPGKDYVHQINRIFQIIGTPHSEEDLQYICSENAWKYIKNLPNPVRPPKPWENIFPNANCNPQAIDLLEKMLVFDPDKRI

TVEEALSHPYL
||||.|.|||.
TVEECLEHPYF
Kinase AqueK131.AA JNK 25-313 40 1.3e-113 383.79 In-house 1-309 (309) Show / Hide 
Range on Protein: 25-313
Range on HMM: 1-309/309
Sequence Identity: 40% (127 aa)

YQELTPINSGAYGQVCSALDTKYGIRVAIKKLYAP--FEHRHNAKKAYREMRILSHLKHENCIGLLDVFSPCEDIEEFSDFYMVMHLMSMDLAKLLKENR
|| | .|..|| | ||.| |.  . ||||||.  |  |. .  .| ||||   .....|.| |... .| | | .||| |.|.|| .|   |  .    .
YQNLKFIGQGAQGIVCMAFDQVTNQRVAIKKMMRPDNFQNWMHWKRAYREFICMKCINHKNIIKMYNCFTPQETLEEFQDVYIVMEYMDWNLCQVIH--S

TSQILSEDHIKFLLYQILCGLKYVHSAGIIHRDLKPSNIAVNPTCDLRILDFGLARQTDRD--MTGYVSTRHYRAPEIMLSWE-NYGKQVDVWSVGCIMA
|   |  . ...|.||..|| |. ||.|||||||||||| ||  |.| |.|||.||  | .  || || || |||||. .    ||   ||.||||||||
TFMELDHERMSYLFYQMCCGIKHLHSMGIIHRDLKPSNIVVNQDCTLKICDFGHARTEDPTFMMTPYVVTRYYRAPEVICGMMDNYKENVDIWSVGCIMA

ELLGSKVLFPGDNQIDQLHKIFEIMGTPSQSLIDKIPHQKTKLYLQSL---KVIKPKNLKNL------L--EIHNND-------ALDLLKKLLTLDPERR
|..  .|||||  .|||  || |  |||... . . . .  . |. ..      .| | . .      .  .. . .       | ||| . |  .|..|
EMIRHHVLFPGKDHIDQWNKIIEFLGTPDPHFMMQMQ-PHVRNYVENRNMDPYYQPYNFHEHFPDTLFPDVMQSEPKDHLTCHMARDLLFRMLVINPDDR

ITVEEALSHPYL
| |..||.|||.
ISVDDALQHPYI
Kinase AqueK131.AA ERK1 25-313 50 3.5e-109 369.02 In-house 1-289 (289) Show / Hide 
Range on Protein: 25-313
Range on HMM: 1-289/289
Sequence Identity: 50% (150 aa)

YQELTPINSGAYGQVCSALDTKYGIRVAIKKLYAPFEHRHNAKKAYREMRILSHLKHENCIGLLDVFSPCEDIEEFSDFYMVMHLMSMDLAKLLKENRTS
| .|  |  |||| ||||.||  . ||||||. .||||    ..  ||..||   |||| |.. |.    . ||.. | |.|  ||  || ||||    .
YTNLQYIGEGAYGMVCSAYDTVHKQRVAIKKI-SPFEHQTYCQRTLREIKILTRFKHENIINIQDIIR-ADTIEQMRDVYIVQCLMETDLYKLLK----T

QILSEDHIKFLLYQILCGLKYVHSAGIIHRDLKPSNIAVNPTCDLRILDFGLARQTDRD------MTGYVSTRHYRAPEIMLSWENYGKQVDVWSVGCIM
| || ||| . ||||| ||||.||| ..||||||||. .| ||||.| |||||| .| .      .| || || ||||||||    | | .|.||||||.
QHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCIL

AELLGSKVLFPGDNQIDQLHKIFEIMGTPSQSLIDKIPHQKTKLYLQSLKVIKPKNLKNLLEIHNNDALDLLKKLLTLDPERRITVEEALSHPYL
||.|  . .|||   .||| .|  ..| |||  .. |  .| . |||||   .   .. |     . ||||| |.||  |..|||||||| ||||
AEMLSNRPIFPGKHYLDQLNHILGVLGSPSQDDLNCIINEKARNYLQSLPHKPKVPWARLFPKADSKALDLLDKMLTFNPHKRITVEEALAHPYL
Kinase AqueK131.AA ERK5 25-313 42 5e-103 348.57 In-house 1-295 (295) Show / Hide 
Range on Protein: 25-313
Range on HMM: 1-295/295
Sequence Identity: 42% (128 aa)

YQELTPINSGAYGQVCSALDTKYGIRVAIKKLYAPFEHRHNAKKAYREMRILSHLKHENCIGLLDVFSPCEDIEEFSDFYMVMHLMSMDLAKLLKENRTS
|. .  |  |||| ||||   | | .|||||.   |.   |||. .||..|| | .|.| | . |.  | . . |. | |.|. ||  || ...     .
YKIIEKIGNGAYGVVCSARRRKNGQQVAIKKIPNAFDVVTNAKRTFRELKILRHFRHDNIIAIRDILMPKVPYSEMKDVYVVFDLMESDLHQIIH---SN

QILSEDHIKFLLYQILCGLKYVHSAGIIHRDLKPSNIAVNPTCDLRILDFGLAR-----QTDRD---MTGYVSTRHYRAPEIMLSWENYGKQVDVWSVGC
| .. .||.. ||||| ||||.||| .|||||||||. ||  |.|.| |||.||      .|.    || || || |||||.|.| ..| . .|||||||
QPFTLEHIRYFLYQILRGLKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTFSPDKHQMFMTEYVATRWYRAPELMFSSHDYTQAIDVWSVGC

IMAELLGSKVLFPGDNQIDQLHKIFEIMGTPSQSLIDKIPHQKTKLYLQS-LKVIKPKNLKNLLEIHNNDALDLLKKLLTLDPERRITVEEALSHPYL
|. |... . .||| | |.||  | ...|.|.  .|  .  .. . |.|. .   .||... .       ||||| ..|  .|  |||| .|| ||.|
IFGEMIARRQMFPGKNYIHQLQLIMMVLGMPPPHMIQAVSADHVYNYFQKNFPNRQPKDWEKVYPKADRQALDLLARMLRFEPSERITVNKALQHPFL
Kinase AqueK131.AA nmo 26-313 41 1.2e-91 282.07 In-house 2-292 (292) Show / Hide 
Range on Protein: 26-313
Range on HMM: 2-292/292
Sequence Identity: 41% (123 aa)

QELTPINSGAYGQVCSALDTKYGIRVAIKKLYAPFEHRHNAKKAYREMRILSHLKHENCIGLLDVFSPCEDIEEFSDFYMVMHLMSMDLAKLLKENRTSQ
|   ||  ||.| | |  | . | |||.||.   |     .|. .||...|.  ||.| . .||.  | . .. | . |.|  ||  || |..      |
QPDRPIGYGAFGVVWSVTDPRDGKRVALKKMPNVFQNLVSCKRVFRELKMLCFFKHDNVLSALDILQPPH-KDFFQEIYVVTELMQSDLHKII---VSPQ

ILSEDHIKFLLYQILCGLKYVHSAGIIHRDLKPSNIAVNPTCDLRILDFGLARQTDRD----MTGYVSTRHYRAPEIMLSWENYGKQVDVWSVGCIMAEL
 || ||.|  ||||| ||||.|||.|.|||.|| |. ||  | |.| ||||||  ..|    ||  | |  ||||||..    |   ||.|||||| |||
HLSSDHVKVFLYQILRGLKYLHSANILHRDIKPGNLLVNSNCVLKICDFGLARVWEQDQSKHMTQEVVTQYYRAPEILMGARHYTSAVDIWSVGCIFAEL

LGSKVLFPGDNQIDQLHKIFEIMGTPSQSLIDKIPH-QKTKLYLQSLKVIKPKNLKNLLE--IHNNDALDLLKKLLTLDPERRITVEEALSHPYL
|| ..||   . |.||. | ...||||.  .       |. .  ...|  . . | .|      . .| .||...|  ||..|| ...|| ||||
LGRRILFQAQSPIQQLQMITDLLGTPSMEDMKYACEGAKAHMLRMPHKPPCLQVLYTLSSPDHATHEAVHLLCRMLHFDPDKRISCKDALAHPYL
Kinase AqueK131.AA ERK7 25-313 37 1.7e-88 300.3 In-house 1-292 (292) Show / Hide 
Range on Protein: 25-313
Range on HMM: 1-292/292
Sequence Identity: 37% (112 aa)

YQELTPINSGAYGQVCSALDTKYGIRVAIKKLYAPFEHRHNAKKAYREMRILSHLK-HENCIGLLDVFSPCEDIEEFSDFYMVMHLMSMDLAKLLKENRT
|. .  .  |||| |  |.| . .  ||.|| .  |  .  | . .||. .|  .. |.| | |..|.    |     |.|.|   |  ||    .    
YEIRKRLGKGAYGIVWKAYDKRTKQVVALKKIFDAFRNQTDAQRTFREIMFLQEFHCHPNIIRLINVIRADNDR----DIYLVFEFMETDLHAVIRK---

SQILSEDHIKFLLYQILCGLKYVHSAGIIHRDLKPSNIAVNPTCDLRILDFGLARQ-TDRD--------MTGYVSTRHYRAPEIMLSWENYGKQVDVWSV
 .|| . | .. .||.|  .||.||. .|||||||||| ..  | ... ||||||  ....        .| || || ||||||.|. ..| | || ||.
GNILKDIHKQYIMYQLLRAIKYMHSGNVIHRDLKPSNILLDSECMVKVCDFGLARSIAQQEEYDEQNPMLTEYVATRWYRAPEILLGSHRYTKGVDMWSI

GCIMAELLGSKVLFPGDNQIDQLHKIFEIMGTPSQSLIDKIPHQKTKLYLQSLKVIKPKNLKNLLEIHNNDALDLLKKLLTLDPERRITVEEALSHPYL
|||..|.|  | .|||   ..|. || |... |.|  |  |  .     |..... |.| |.....   .||.||||.|| . |..|.|.|.||.||| 
GCILGEMLRGKPMFPGTSTMNQIEKILETIPKPTQEDIEAIGSHYAWNMLEQMNQQKRKTLDQMMPQCCDDAIDLLKRLLVFNPKKRLTAEQALQHPYV
Kinase AqueK131.AA S_TKc 25-313 31 2e-88 300.98 SMART 1-231 (231) Show / Hide 
Range on Protein: 25-313
Range on HMM: 1-231/231
Sequence Identity: 31% (96 aa)

YQELTPINSGAYGQVCSALDTKYGIRVAIKKLYAPFEHRHNAKKAYREMRILSHLKHENCIGLLDVFSPCEDIEEFSDFYMVMHLMSM---DLAKLLKEN
|. | .| .||.|.|. . ..| | .||||..          ....||..||.. .|.| . |.|||         ...|||| ...    || ...|..
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-------DHLYMVMEYCDGDLGDLFDYIKKR

RTS---QILSEDHIKFLLYQILCGLKYVHSAGIIHRDLKPSNIAVNPTCDLRILDFGLARQTDRDMTGYVSTRHYRAPEIMLSWENYGK-QVDVWSVGCI
..    . ..| |..|..|||.|.|.| || |||||||||.|| ..    . | |||||||     | .. |..|.|||..     |||  .|.||.|||
GRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCI

MAELLGSKVLFPGDNQIDQLHKIFEIMGTPSQSLIDKIPHQKTKLYLQSLKVIKPKNLKNLLEIHNNDALDLLKKLLTLDPERRITVEEALS-------H
..|.|  . .||      |....|...|                                       .|.|...|.|. |||.|.|. |||        |
LYEMLCGYPPFP------QMQMMFKKIG-------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCH

PYL
|..
PWF
Kinase AqueK131.AA Pkinase 25-313 30 5.3e-84 290.18 Pfam 1-293 (293) Show / Hide 
Range on Protein: 25-313
Range on HMM: 1-293/293
Sequence Identity: 30% (98 aa)

YQELTPINSGAYGQVCSALDTKYGIRVAIKKLYAPFEHRHNAKKAYR--EMRILSHLKHENCIGLLDVFSPCEDIEEFSDFYMVMHLMSM-----DLAKL
|. . .| ||..|.|. . . ..|..||.|..  . |.    . . |  | .|. .|.|.| . |.|.|         .. |||| .. .     ||. .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED------KDHIYMVMEYCEGGLYVMDLFDY

LKENRTSQIL--SEDHIKFLLYQILCGLKYVHSAGIIHRDLKPSNIAVNPTCDL----RILDFGLARQ---TDRDMTGYVSTRHYRAPEIMLSWENYGKQ
..  . .  .  ||...|| .||||.||.| || |||||||||.|| .. ....    .| |||||.|    .. ||... |..|.|||. .. . ||. 
IST-WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDYNNS-MTTFCGTPWYMAPEVIRGGQYYGPK

VDVWSVGCIMAELLGSKVLFPGD----NQIDQLHKIFEIMGTPSQSLIDKI--------PHQKTKLYLQSLKVIKPKNLKNLLEIHNNDALDLLKKLLTL
||.||.|||..|.|  . .|||.    | .||...|..|||.|  . ...         .| . .           . .. .    . ...|..|..|..
VDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRH-W-H-----------F-HWTF-HNWSEECKDFIKWCLCK

DPERRITVEEALSHPYL
||..|.| |..| ||..
DPKKRPTAEQILQHPWF
Kinase AqueK131.AA MAPK-Unclassified 25-178 46 2e-56 193.8 In-house 1-157 (575) Show / Hide 
Range on Protein: 25-178
Range on HMM: 1-157/575
Sequence Identity: 46% (74 aa)

YQELTPINSGAYGQVCSALDTKY-GIRVAIKKLYAPFEHRHNAKKAYREMRILSHLKHENCIGLLDVFSPCEDIE-EFSDFYMVMHLMSM---DLAKLLK
|     | |||||||| | |.|  .  |||||.   |.    .| . || ||| .| |.| | . |.| . |.   || | | || .|     || ...|
YEYQKNIGSGAYGQVCRAMDKKNQNQQVAIKKVNHIFHNHTDCKRVLREIRILRYLNHPNIIQIQDIFYNKELHNQEFDDIYIVMDYMQTSLFDLHQIIK

ENR-TSQILSEDHIKFLLYQILCGLKYVHSAGIIHRDLKPSNIAVNPTCDLRILDFGLAR
 |  .   ... ||. ..|||| |||| |||.||||||||||. .|  | .|| |||..|
SNQDH---WCHQHIQYFFYQILRGLKYLHSACIIHRDLKPSNLLINQDCSVRICDFGMSR
Kinase AqueK131.AA MAPK-Unclassified 179-313 31 6.7e-47 162.13 In-house 400-575 (575) Show / Hide 
Range on Protein: 179-313
Range on HMM: 400-575/575
Sequence Identity: 31% (55 aa)

QTDRDMTGYVSTRHYRAPEIMLSWENYGKQVDVWSVGCIMAELLGS-----------KVLFPGDN--------------------QIDQLHKIFEIMGTP
.. ..||.||.|| |||||||||  .|..||| ||.||| ||..             . ||||..                     .||.  ||.  |.|
HHCYHMTQYVVTRWYRAPEIMLSMHEYDTQVDIWSIGCIFAEMMQMYDRHNPTFSDHRPLFPGQDCFPITPDRNNDVDQGGFPHSHQDQIKMIFDYLGMP

SQSLIDKIPHQKTKLYLQSLKVIKPKNLKNLLEIHNN----------DALDLLKKLLTLDPERRITVEEALSHPYL
 .  .. |   ... |.||.|  .|   . |    .           ...|...|.|  .| .||| ..||.||| 
PEEDCNFITCDSARKYIQSFKCKTPVHFTDLMFCKAPGDDQIVRGNCECIDFVQKMLQFNPWKRITADQALEHPYF
Kinase AqueK131.AA TyrKc 25-279 23 8.7e-13 -15.91 SMART 1-280 (280) Show / Hide 
Range on Protein: 25-279
Range on HMM: 1-280/280
Sequence Identity: 23% (69 aa)

YQELTPINSGAYGQVCSALDTKYGIRVAIKKLYAPFEHRHNAKKAYREMRILSHL--KHENCIGLLDVFSPCEDIEEF---SDFYMVMHLMSM-DLAKLL
 . .  . .||.|.|. .  .   | ||.|.| .        .  .||.||...|  .|.| . |. | .  .    |      ..|| .|.  || . |
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRN--FMYIEPLMIVMEYMPHGDLKDYL

KENRTSQILSEDHIKFLLYQILCGLKYVHSAGIIHRDLKPSNIAVNPTCDLRILDFGLARQTDRD-----MTGYVSTR---HYR--------APEIMLSW
...|    |. ..     .|| ||  | || ..|||||   |. |.     .| ||||.|  . |      . | ...   . .        ||| .   
RKHRPK--LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI---

ENYG---KQVDVWSVGCIMAELL-GSKVLFPGDNQIDQLHKIFEIMGTPSQSLIDKIPHQ---------KTKLYLQSLKVIKP--------KNLKNLL
 |||    . |||| |  | |..   .   ||. |     . .|..    |    ..|.           ...|   ..  .         .... ..
-NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQ--MMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF