Gene AqueK140 (A.queenslandica)

AqueK140

Species: A.queenslandica
Alias: AqueK140
External Links:
Annotation:

Classification

Group: TKL
Family: MLK
Subfamily: HH-B

Sequence

Name Sequence Type Origin Length Description Download
AqueK140.AA Protein None 860 None Fasta, JSON
AqueK140.kin_dom Protein Kinase Domain None 239 None Fasta, JSON

Protein domain

Protein domains of AqueK140.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kelch_1 AqueK140.AA Kelch_1 27-74 18 4e-06 25.57 Pfam 1-45 (45) Show / Hide 
Range on Protein: 27-74
Range on HMM: 1-45/45
Sequence Identity: 18% (9 aa)

GVVSYAAAAIGREIFYFGGYCNHDDCYYNSLYSFNVDTFSWKELSPTT
  ......... .|. .||...    | || ......| .|....| .
PRCGHGVCVHNGKIYVIGGCDG---QYLNSVECYDPETNQWTRCPPMP
Kelch_2 AqueK140.AA Kelch_2 27-74 21 0.018054 13.51 Pfam 1-51 (51) Show / Hide 
Range on Protein: 27-74
Range on HMM: 1-51/51
Sequence Identity: 21% (11 aa)

GVVSYAAAAIGREIFYFGGY---CNHDDCYYNSLYSFNVDTFSWKELSPTT
. .. |.. .|  |. ||||     ..||. .... .. .| .|.....  
PRYCHASCVPGGKIYVFGGYCRHTHNNDCWSMDIWWWDPETHRWTCVPRMP
Kelch_2 AqueK140.AA Kelch_2 79-147 10 2.026728 5.72 Pfam 1-51 (51) Show / Hide 
Range on Protein: 79-147
Range on HMM: 1-51/51
Sequence Identity: 10% (7 aa)

PMMKANCDMIAIKKNGEDYLVVIGGFGPSSNNTPPQPGAQYSGGVHQRCNEIHFYKLSTGQWISPTVTG
|..   . ..      .. ..|.||.              ....   ... |... ..| .|   .. .
PRYCHASCVP------GGKIYVFGGYC------------RHTHNNDCWSMDIWWWDPETHRWTCVPRMP
Kelch_1 AqueK140.AA Kelch_1 95-140 21 22.109143 1.55 Pfam 11-38 (45) Show / Hide 
Range on Protein: 95-140
Range on HMM: 11-38/45
Sequence Identity: 21% (10 aa)

EDYLVVIGGFGPSSNNTPPQPGAQYSGGVHQRCNEIHFYKLSTGQW
.... ||||. .                  |. | .  | ..|.||
NGKIYVIGGCDG------------------QYLNSVECYDPETNQW
Kelch_1 AqueK140.AA Kelch_1 222-253 20 0.004375 14.83 Pfam 11-45 (45) Show / Hide 
Range on Protein: 222-253
Range on HMM: 11-45/45
Sequence Identity: 20% (7 aa)

GPHLLVVGGSG---TNDIWIFDINNKSWKELVNIP
. .. |.||.    .|.....|  ...|... . |
NGKIYVIGGCDGQYLNSVECYDPETNQWTRCPPMP
Kelch_2 AqueK140.AA Kelch_2 208-253 23 0.004906 15.66 Pfam 1-51 (51) Show / Hide 
Range on Protein: 208-253
Range on HMM: 1-51/51
Sequence Identity: 23% (13 aa)

ERDAHSSVLINTGSGPHLLVVGGS---------GTNDIWIFDINNKSWKELVNIP
 |  |.|. .    |  ..|.||.          ..|||..| . ..|...  .|
PRYCHASCVP----GGKIYVFGGYCRHTHNNDCWSMDIWWWDPETHRWTCVPRMP
Kinase AqueK140.AA TKL 495-725 18 9e-45 155.06 In-house 1-364 (364) Show / Hide 
Range on Protein: 495-725
Range on HMM: 1-364/364
Sequence Identity: 18% (67 aa)

LGKGGWGEVKVASFRG----------LKVAAKCLYEVIISPYNI-------------------------GTFSREMNIASKIRHPNLLQFIGVTTEGN--
.|.|| |||  . .||            || | . .   .  ..                          .. .|... |..||||..||.|. ....  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------PIILTELM-PTSLRKELESGGVAYPAILSISLDVACALNYLHLFKP-----HPILHRDVSSANVLLQPVGV-----------GWRAKV
            . | .|..   ||.  |       . .....||.|...||||  .|      ||.|||  |.|.|.   .             |..|.
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-----WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKI

SDYGTVS-LQPLTS--------------------TCSPG-NPVYSAPEA--GNP--------------REHSPAMDVFSYGVLLIEMVVCE--FPDVGKR
.|.|.   ... ..                    |.... .| . |||.  |..              .| |...||.|.|..| |.. ..  . | . .
CDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPYM

------------VAQIKAIKRPALK--------------------NLIERCLIENYKQRPTMSDIINEI
            .  ..  .|| ..                    .|...|  .. ..||....|. ..
PMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase AqueK140.AA CZAK 492-683 30 2.1e-24 85.6 In-house 4-221 (279) Show / Hide 
Range on Protein: 492-683
Range on HMM: 4-221/279
Sequence Identity: 30% (68 aa)

EVVLGKGGWGEVKVASFRGLKVAAKCLYEVIISPYNIGT------FSREMNIASKIRHPNLLQFIGVTTEGN---PIILTELMP-TSLRKELE--SGGVA
. . |.|  |||. |  ||  || | ..   ..  |         | .|  | || .||| .||.|. .|..     | .| |   |||. |   .  . 
GQTIGQGFFGEVYKAYWRGKDVAIKIIH--RNQFRNKDENKEENMFQKEVSIMSKLCHPNCVQFLGACSEDGPNHHCIVMEWMGGGSLRRLLTDHYFYHK

Y-PAI-LSISLDVACALNYLHL-FKPHPILHRDVSSANVLLQPVGV----------GWRAKVSDYGTV---SLQPLTSTCSPGNPVYSAPEAGNPREHSP
  | . ... .|.|   ||||  .|| |||||| || |.||                  .|..|.|       ||   | . |   . |||       ..
QNPHLQWNMAIDIARGMNYLHDNWKPNPILHRDLSSRNILLDHSYTPKNPVVSSRQDIICKINDFGLSREMMEQPFEMTQTMGCLCWMAPECFKGENYTE

AMDVFSYGVLLIEMVVCEFP
  ||.|.| .| ... |. |
KVDVYSFGMILWCIITCDQP
S_TKc AqueK140.AA S_TKc 489-731 23 8.5e-23 82.97 SMART 1-231 (231) Show / Hide 
Range on Protein: 489-731
Range on HMM: 1-231/231
Sequence Identity: 23% (61 aa)

TMTEVVLGKGGWGEVKVASFRG--LKVAAKCLYEVIISPYNIGTFSREMNIASKIRHPNLLQFIGVTTEGNPIILTELMPT---SLRKELESGG------
     ..|||. |.|. .  ..   .|| |..           .. ||..| .| .|||. ....|  ...  . .|....   .|.. ... |      
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-VAYPAILSISLDVACALNYLHLFKPHPILHRDVSSANVLLQPVGVGWRAKVSDYGTVSLQPLTSTCSPGNPVYSAPEAGNPREHSP-AMDVFSYGVLLI
      . ..   ..|||.|.|  .   |.|||.  .|.||       . |..| |   .   |. |  | | | |||      ... . |. | |..|.
PFPE-HARFYMYQICCALEYCHSHG---IIHRDLKPENILLDE-----HIKICDFGLARQL--TTFC--GTPWYMAPEVL---GYGKCKCDWWSCGCILY

EMVVCEFPDVGKRVAQIKAIKRPALKNLIERCLIENYKQRPTMSDIIN---EIKEKIDL
||.. . |      . .| |. | .|..|..||  . ..|||  .. .   .||    .
EMLCGYPPFP-QMQMMFKKIGSPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK140.AA TK 533-725 12 4.7e-21 66.64 In-house 87-486 (486) Show / Hide 
Range on Protein: 533-725
Range on HMM: 87-486/486
Sequence Identity: 12% (51 aa)

REMNIASKIR-----HPNLLQFIGVTTEGN-------------PIILTELMP-TS----LRKELESGG--------------------------------
.|...... .     |||.....|| |.|              ..|..|.||  .    ||. | .                                  
EEAEEMKMMCHSLGHHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITY

---------------------------------------------VAYPAILSISLDVACALNYLHLFKPHPI----LHRDVSSANVLLQPVGV------
                                             .  .  | .....||.. |||  .         |||.   |.|.   .|      
SHESNSPCPEEQDYDDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCE-FIQNFVHRDLAARNCLVGENNVCKWHFD

--GWRAKVSDYG--------TVSLQPLTSTCSPGNPVY-----------------------------SAPEAGN---------PREHSPAMDVFSYGVLL
  |  .|..|.|             .  .     .. .                              |||. |          . .... ||.|.|||.
GCGPVCKIADFGLSRQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLM

IEMVV-C-EFPDVGKR-------------VAQIKAI-----------------KRPALKN-------------------LIERCLIENYKQRPTMSDIIN
 |..  . | .  |               . ....                  ..|..                     |. .|  .. ..|||.|.. .
WEIFTYGQEPYYGGMSNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHE

EI
..
QL
Kinase AqueK140.AA MLK 489-683 23 6e-21 69.51 In-house 1-235 (291) Show / Hide 
Range on Protein: 489-683
Range on HMM: 1-235/291
Sequence Identity: 23% (57 aa)

TMTEVVLGKGGWGEVKVASFRGLKVAAKC--LYEVIISPYNIGT-------FSREMNIASKIRHPN----LLQFIGVTTE-GN-PIILTELMPT-SLRKE
  .. ..|.|. |.|  . .|.  . ||   ...| .... ..        | .| .......|||      || || .. ..   |..| ..  ||   
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNV

LESG---------------GVAYPAILSISLDVACALNYLHLFKPHPILHRDVSSANVLLQP------VGVGWRAKVSDYGTVS-LQPL-T-STCSPGNP
| ..                .    .....|..| ...|||  .|.|| |||  | |.|.         |.   .|..| ||.  ..   |  .. .|..
LHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGT---LKICDFGTSRDWHQMCTNMMSNAGTY

VYSAPEA---GNPREHSPAMDVFSYGVLLIEMVVCEFP
 . |||.         | . ||.|.||.| ||. .| |
AWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVP
Kinase AqueK140.AA TKL-Unique 494-678 25 9.3e-20 66.48 In-house 4-222 (290) Show / Hide 
Range on Protein: 494-678
Range on HMM: 4-222/290
Sequence Identity: 25% (55 aa)

VLGKGGWGEVKVASFRGLKVAAKCLY-EVIISPYNIGTFSREMNIASKIR-HPNLLQFIGVTT-----EGNPIILTELMPT-SLRKELE-----------
..| || |.|. . .|| .|| | .  .  .|.  . .|..| |. .|.. |||.....|...     ..| .| .| .|  ||.. |            
KIGEGGYGQVYKGKWRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNNNNN

SGGVAYPAILSISLDVACALNYLHLFKPHPILHRDVSSANVLLQPV--GVGWRAKVSDYGTVSLQP--LTSTCS----------PGNPVYSAPEAGNP--
.    .  .... .|.| ...|||  .|  |.|||  | |.|.        |..|..| |.. ..   ...| .           |.. ..|||  .   
NCKLNMQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLRMNF

REHSPAMDVFSYGVLLIEMV
   |   ||.|.|. |.|..
CQYSEKSDVYSFGIVLWEIA
Kinase AqueK140.AA Pkinase 489-725 18 3.6e-18 65.33 Pfam 1-293 (293) Show / Hide 
Range on Protein: 489-725
Range on HMM: 1-293/293
Sequence Identity: 18% (55 aa)

TMTEVVLGKGGWGEVKVASFRGLK--VAAKCLYEVIISPYNIGTFSR--EMNIASKIRHPNLLQFIGVT-TEGNPIILTELMPT-----SLRKELE---S
  .. ..|.|. |.|. .  .|    || |..  . ...    |  |  |  |  ...||| ......  ..... . .|...      .|   ..   .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GGV--AYPAILSISLDVACALNYLHLFKPHPILHRDVSSANVLLQ-PVGVGWRAKVSDYGTVS---LQPLTSTCSP-GNPVYSAPEAGN-PREHSPAMDV
|..   .  . .. . ....|.|.|      |.|||. ..|.|.     .. . |..| |      . . . . .. | | | |||  .  ....|. |.
GCFYFSEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDM

FSYGVLLIEMVVCEFPDVGK----------RVAQIKA-------IKR---------------------PALKNLIERCLIENYKQRPTMSDIINE--I
.|.|..|.||.  ..|  |.          ....|.         .                      ...| .|..||  . |.|||  .| .   .
WSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase AqueK140.AA DRK 490-632 35 4.6e-16 50.93 In-house 2-145 (258) Show / Hide 
Range on Protein: 490-632
Range on HMM: 2-145/258
Sequence Identity: 35% (52 aa)

MTEVVLGKGGWGEVKVASFRGLKVAAKCLYEVIIS-PYNIGTFSREMNIASKIRHPNLLQFIGVTTE-GNPIILTELMPT-SLRKEL--ESGGVAYPAIL
   .  |.|..|||   . || .|| | |    |     .  | || |. .. ||||  ||.|  ..   . | .| ||  || . |  ||     | ..
KIGNRIGRGNYGEVFRGTWRGTQVAVKMLFNHNINDENFLNEFHREINLMCQLRHPNICQFMGTCNNPPDICICMEYMPRGSLYNILHDESIEMDWPLMK

SISLDVACALNYLHLFKPHPILHRDVSSANVLLQPVGVGWRAKVSDYG
.. .|.|  ..|||   |  |.|||  | | |   |   |. ||.|.|
QMMFDCAKGMIYLHCCNPI-IIHRDLKSHNLL---VDEHWQVKVADFG
Kinase AqueK140.AA Dicty4 491-632 32 6.1e-16 49.81 In-house 3-159 (277) Show / Hide 
Range on Protein: 491-632
Range on HMM: 3-159/277
Sequence Identity: 32% (53 aa)

TEVVLGKGGWGEVKVASFRGLKVAAKCL--YEVIISPYNIGTFSREMNIASKIRHPNLLQFIGVTT-----EGNPIILTELM-PTSLRKELES------G
.|. .|||. |||  .. || .|| | |    .  . . .  | .| .| .||||||...| |  |      | . | ||.|  ..| . | .       
IEQRIGKGSFGEVYKGTWRGKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSEQQQ

GVAYP--AILS---ISLDVACALNYLHLFKPHPILHRDVSSANVLLQPVGVGWRAKVSDYG
 .  .   |..   . .|.|  .|.||   |  |.|||  |.| |   |   ||.||.| |
SIKLDWPLIKRAMRMAFDAARGMNWLHCCNPV-IIHRDLKSHNLL---VDKNWRVKVCDFG
TyrKc AqueK140.AA TyrKc 488-725 23 4.9e-15 20.35 SMART 1-280 (280) Show / Hide 
Range on Protein: 488-725
Range on HMM: 1-280/280
Sequence Identity: 23% (70 aa)

ITMTEVVLGKGGWGEVKVASFRGLKVAAKCLYEVIISPYNIGTFSREMNIASKI--RHPNLLQFIGVTTE--------GNPIILTELMPT-SLRKELESG
||. . .|| |  |||  .  . ..|| |.| |       .  | ||..| .|.  .|||.....|| |.        . . |..|.||  .|.. | . 
ITLGK-KLGEGAFGEVYKGTWK-IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKH

G--VAYPAILSISLDVACALNYLHLFKPHPILHRDVSSANVLLQPVGVGWRAKVSDYGTVSLQPLT--------STCS----PGN---PV-YSAPEAGNP
.  .  .  ||.....||  .|||    ... |||    |.|.   .   ..|.|| |                   .     |.   |.   |||. | 
RPKLCMKDLLSFCWQIACGMEYLHS---KNCIHRDLAARNCLVGENH---TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINY

REHSPAMDVFSYGVLLIEMV-------------------VCEFPDVGKRVAQIKA-------IKRPALKNLIERCLIENYKQRPTMSDIINEI
.. ... ||.|.||.. |.                    | |. . |.|  | .        .  ... .....|  |. ..|||.|.|. ..
GKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase AqueK140.AA Dicty5 526-677 27 1.8e-14 46.22 In-house 38-196 (260) Show / Hide 
Range on Protein: 526-677
Range on HMM: 38-196/260
Sequence Identity: 27% (46 aa)

YNIGTFSREMNIASKIR--HPNLLQFIGVTTEGNPI--ILTELMPT-SLRKELESGGV------AYPAILSISLDVACALNYLHLFKPHPILHRDVSSAN
...  | ||  | | .   |||.  . |  .       ..||.    ||.  |           ||. .|.. .|.| .. .||      | |||. | |
FDWNEFYREVTIMSIFQSDHPNFIRCYGAHQYNDKYPFHVTEYCHNGSLFNYLNDQRKTTGQPIAYFQQLHMAIDIAQSMRHLHSMN---IIHRDLKSMN

VLLQPVGVGWRAKVSDYGT---VSLQPLTSTCSPGNPVYSAPEAGNPREHSPAMDVFSYGVLLIEM
.|.      | .|. |.||   | .. .  |   | . . |.|  | .      ||.|.|. | ||
FLIT---ENWKIKIIDFGTSRFVDNR-YHMTMHVGTQCWMACELFNGQPYHQKCDVYSFGIVLWEM
Pkinase_Tyr AqueK140.AA Pkinase_Tyr 488-617 26 6.4e-13 44.39 Pfam 1-144 (270) Show / Hide 
Range on Protein: 488-617
Range on HMM: 1-144/270
Sequence Identity: 26% (39 aa)

ITMTEVVLGKGGWGEVKVASFR------GLKVAAKCLYEVIISPYN--IGTFSREMNIASKI-RHPNLLQFIGVTT-EGNP---IILTELMPT-SLRKEL
||. .. ||.|  |||. .  .      ...|| |.|     .. .  .  | ||..| ... .|||.....|| | .| |   .| .|.||  .|.. |
ITFGKK-LGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

ESG-----GVAYPAILSISLDVACALNYLHLFKPHPILHRDVSSANVLL
 .       .  . .|......|....||.  .   . |||.   |.|.
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKN---CIHRDLAARNCLV
Kinase AqueK140.AA LISK 494-552 31 1.4e-11 33.71 In-house 1-64 (296) Show / Hide 
Range on Protein: 494-552
Range on HMM: 1-64/296
Sequence Identity: 31% (20 aa)

VLGKGGWGEVKVASFR--GLKVAAKCLY---EVIISPYNIGTFSREMNIASKIRHPNLLQFIGV
..|||. |.|   . |  |  .| | .    .. . | .. .. ||. .  ..|||| .||.||
EIGKGFFGKVYKGTHRQTGQVMAIKMIHRQPNDPNDPEYQKFMLREVQMMKNLRHPNIVQFMGV
Kinase AqueK140.AA LRRK 489-674 21 1.5e-10 33.51 In-house 1-272 (351) Show / Hide 
Range on Protein: 489-674
Range on HMM: 1-272/351
Sequence Identity: 21% (60 aa)

TMTEVVLGKGGWG-EVKVASFRG----------------------------LKVAAKCLYE--------------------------------VIISPYN
 . |  .|.|| | .|  | .||                             .||.| .                                   . .. .
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

IGTFSREMNIASKIRHPNLLQFIGVTTEGNPIIL-TELMPT-SLRKELE---SGG------V-AYPAILSISLDVACALNYLHLFKPHPILHRDVSSANV
  .| .|. | |. .|||... .|..   .|... .|..|  .| . |.   . |      .     .| |.|..| ...||| ..| ||.|||  | |.
FREFRHEVWIMSHLNHPNIVSLKGFCI--HPLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNP-PIIHRDLKSPNI

LL----QP-----VGVGWRAKVSDYGTVS----LQP-LTSTCSPGNPVYSAPEAGNPR---EHSPAMDVFSYGVLL
||    |.     ..    ||..|.|. .    ... ....|  |||.. |||  .     | .   |..|.|..|
LLWSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMGVAKGCV-GNPGWMAPEIMRYNGEEEYTEKVDCYSFGMIL
Kinase AqueK140.AA LISK 584-632 42 5e-06 15.37 In-house 104-150 (296) Show / Hide 
Range on Protein: 584-632
Range on HMM: 104-150/296
Sequence Identity: 42% (21 aa)

LSISLDVACALNYLHLFKPHPILHRDVSSANVLLQPV-GVGWRAKVSDYG
..|.||.||.. |||  .   |.|||  | |.|.      .||.|| | |
VKIALDIACGMSYLHSMN---IIHRDLKSKNCLVRENDNNQWRIKVCDFG
Kinase AqueK140.AA Dicty4 698-727 28 7e-06 15.75 In-house 246-277 (277) Show / Hide 
Range on Protein: 698-727
Range on HMM: 246-277/277
Sequence Identity: 28% (9 aa)

PALKNLIERCLIENYKQRPTMSDIINE--IKE
| .| ||..|. .. ..||... ||..    .
PSWKHLIQWCWDHDPQHRPSFEEIIQRRILEH
Kinase AqueK140.AA LRRK 698-727 26 2.2e-05 15.0 In-house 322-351 (351) Show / Hide 
Range on Protein: 698-727
Range on HMM: 322-351/351
Sequence Identity: 26% (8 aa)

PALKNLIERCLIENYKQRPTMSDIINEIKE
. ...||. |  .. |.||..|.|.  ...
HMYQDLIQHCWQHDPKKRPHFSQIVKRLSQ
Kinase AqueK140.AA TKL-Unique 700-725 30 2.8e-05 14.75 In-house 265-290 (290) Show / Hide 
Range on Protein: 700-725
Range on HMM: 265-290/290
Sequence Identity: 30% (8 aa)

LKNLIERCLIENYKQRPTMSDIINEI
...||..|   .  |||. ..||...
YRDLIQQCWHHDPSQRPSFDEIIHRL
Kinase AqueK140.AA DRK 703-728 30 0.000447 9.74 In-house 234-258 (258) Show / Hide 
Range on Protein: 703-728
Range on HMM: 234-258/258
Sequence Identity: 30% (8 aa)

LIERCLIENYKQRPTMSDIINEIKEK
|. .|. |.  .||.| ... |. | 
LMNDCWNEDPQHRPSMQECL-ERLEA
Kinase AqueK140.AA MLK 700-725 23 0.000557 9.85 In-house 266-291 (291) Show / Hide 
Range on Protein: 700-725
Range on HMM: 266-291/291
Sequence Identity: 23% (6 aa)

LKNLIERCLIENYKQRPTMSDIINEI
.|.|...|  .. ..||... |. . 
WKKLMKQCWNQDPHKRPSFRQIVQHL
Kinase AqueK140.AA Pkinase_Tyr 698-725 25 0.003229 11.52 Pfam 243-270 (270) Show / Hide 
Range on Protein: 698-725
Range on HMM: 243-270/270
Sequence Identity: 25% (7 aa)

PALKNLIERCLIENYKQRPTMSDIINEI
. . .|. .|  .. ..|||.|.|....
DEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase AqueK140.AA LISK 666-678 53 0.004028 5.76 In-house 221-233 (296) Show / Hide 
Range on Protein: 666-678
Range on HMM: 221-233/296
Sequence Identity: 53% (7 aa)

DVFSYGVLLIEMV
||||.|..|.|..
DVFSFGIVLCEII
Kinase AqueK140.AA Dicty5 702-729 28 0.1036 1.66 In-house 233-260 (260) Show / Hide 
Range on Protein: 702-729
Range on HMM: 233-260/260
Sequence Identity: 28% (8 aa)

NLIERCLIENYKQRPTMSDIINEIKEKI
|||. |  .  ..||.   |.  ..  |
NLIKKCWQQKPHNRPSFKEICKYFESII
Kinase AqueK140.AA Pkinase_Tyr 666-678 53 1.447269 2.54 Pfam 196-208 (270) Show / Hide 
Range on Protein: 666-678
Range on HMM: 196-208/270
Sequence Identity: 53% (7 aa)

DVFSYGVLLIEMV
|| |.|||. |..
DVWSFGVLMWEIF
Ank AqueK140.AA Ank 765-797 42 8.1e-09 36.07 Pfam 1-33 (33) Show / Hide 
Range on Protein: 765-797
Range on HMM: 1-33/33
Sequence Identity: 42% (14 aa)

ELQTALMLSVSSGSLGLVTLLLEAGADINAQDK
. .|.|.| ...|..  |..||..|||.||||.
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD
Ank AqueK140.AA Ank 798-831 32 0.006568 14.75 Pfam 1-33 (33) Show / Hide 
Range on Protein: 798-831
Range on HMM: 1-33/33
Sequence Identity: 32% (11 aa)

DGSTSLMFACEKGYTTISQLLLSHPSCNTQLKDN
|| | |. ||..|.| . ..||.   ..  ..|.
DGFTPLHLACRCGHTEVVKMLLQ-HGADVNAQDD
Ank AqueK140.AA Ank 832-852 42 1.314311 6.45 Pfam 1-21 (33) Show / Hide 
Range on Protein: 832-852
Range on HMM: 1-21/33
Sequence Identity: 42% (9 aa)

DNQTALDIAKSCGHTQLCDIL
| .|.| .| .||||. .  |
DGFTPLHLACRCGHTEVVKML