Gene AqueK171 (A.queenslandica)

AqueK171

Species: A.queenslandica
Alias: AqueK171
External Links:
Annotation:

Classification

Group: Other
Family: NAK
Subfamily: GAK

Sequence

Name Sequence Type Origin Length Description Download
AqueK171.AA Protein None 582 None Fasta, JSON
AqueK171.kin_dom Protein Kinase Domain None 174 None Fasta, JSON

Protein domain

Protein domains of AqueK171.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase AqueK171.AA GAK 238-411 45 4.7e-76 252.21 In-house 1-179 (277) Show / Hide 
Range on Protein: 238-411
Range on HMM: 1-179/277
Sequence Identity: 45% (83 aa)

LKVKKVIAEGGYGFVFVAQDTSTGIDYALKRQIVA-SENIKAIKQEITFLTQLSGHPHIIHFIGAAS-SKD-PAGGSAEFLIVTELITGGELVDIVN---
. |..||||||..||.||||. || .||||| . .  .  .|| .|| .. .|.||. |. |..|.. |..    . ||.|. .|.  .. |||.     
YRVRCVIAEGGFAFVYVAQDVQTGREYALKRMLSHDMQANRAIINEICMMKKLQGHENIVQFCDASYISREESNQSQAEYLLLMEYCKFSQLVDCLKRME

-TRSLSPHQVLRVFYETCQAIAHMHSQTPPIIHRDIKVGVENLLLTDKGSVKLCDFGSATTQRLTPDHSWSATQRGLREDE
    .|.  |||.|| .| |..||||| |||||||||  .||.|.  ..  ||||||||||  . || |||| .| . |||
CYKPFSCDCVLRIFYQMCRAVQHMHSQKPPIIHRDIK--IENFLIGNQKTIKLCDFGSATTKSHYPDYSWSAQKRSMVEDE
Kinase AqueK171.AA NAK 238-411 34 3.3e-64 213.2 In-house 1-195 (299) Show / Hide 
Range on Protein: 238-411
Range on HMM: 1-195/299
Sequence Identity: 34% (67 aa)

LKVKKVIAEGGYGFVFVAQ---------DTSTGIDYALKRQIVAS--ENIKAIKQEITFLTQLSGHPHIIHFIG-AASSKDPAGGSAEFLIVTELITGGE
..|.|..||||...|...|         ..|.|  |||||.|. |  . ..|.|.|| .. .|..|..|. .|. .....|   |. | ... |.  .| 
YTVEKYLAEGGFSYVYLVQDNYINHPDNPNSNGEKYALKRMICHSDEQDLNACKREIEMMKKLQHHNNIVQYIDSHINERDDSNGTWEVFLLMEYCCHGS

LVDIVNTRS------LSPHQVLRVFYETCQAIAHMHSQTP--PIIHRDIKVGVENLLLTD---KGSVKLCDFGSATTQRLTPDHSWSATQRGLREDE
|.|. |.|       ..  ..|. |...|.....||.. |  ||||||||  .||.|| .   .|  |||||||.||....|. .|.| .| . .|.
LWDLMNKRLMDKGTCFTEDEILQIFCDVCEGVQAMHQCQPPKPIIHRDIK--IENILLSESHHDGNYKLCDFGSMTTAIIQPENRWEAQYRSMVQDW
Kinase AqueK171.AA BIKE 238-396 34 3.7e-37 129.77 In-house 1-162 (267) Show / Hide 
Range on Protein: 238-396
Range on HMM: 1-162/267
Sequence Identity: 34% (57 aa)

LKVKKVIAEGGYGFVFVAQDTSTGIDYALKRQIVASE-NIKAIKQEITFLTQLSGHPHIIHFIGAASSKDPAGGSAEFLIVTELITGGELVDIVNTRSLS
  | ...||||.  ||... .. |. .||||. |  | .... . |.... |.|||  |. .. ..      .|  | .| .|   . ..|.. | |   
VTVEEQLAEGGFAMVFLVR-DHKGNKCALKRMYVNNEHDLNVCCREHQIMKQCSGHKNIVGYVDCYINCIG-NGVWECMILMEYCRH-QVVNMMNQRLQQ

P-----HQVLRVFYETCQAIAHMHSQTPPIIHRDIKVGVENLLLTDKG--SVKLCDFGSATTQRLTP
        ||..| ..| |.. .|    |||||| |  ||| ||.|.|     ||||||||.. | |
GQYFTEQEVLQIFCDVCEAVSRLHHCQTPIIHRDLK--VENILLHDHGPPHYVLCDFGSATNKFLNP
Kinase AqueK171.AA NAK-Unclassified 238-396 18 2.8e-33 113.42 In-house 1-286 (405) Show / Hide 
Range on Protein: 238-396
Range on HMM: 1-286/405
Sequence Identity: 18% (54 aa)

LKVKKVIAEGGYGFVFVAQ--------D------TSTGIDYALKRQIVASEN-IKAIKQEITFLTQLSGHPHIIHFIGAASSKDPAG-GSAEFLIVTELI
 .. . .|||| .||....        |       |..  |.||| |. .|. ... | ||     . .||.|.  |.   ..   . .| | ... |. 
YTIVRYLAEGGFSFVYLVKFSKYINPPDNTASVPHSNSNMYCLKRMICQDEESLNTMKREIDVMKRFRNHPNIVKYIDHHIMRENHNNQSYEVFMLMEYC

TGGELVDIVN------TRS-----LSPHQVLRVFYETCQAIAHMHSQTP--------------------------------------------PIIHRDI
 .| |.|. |      .|      ..   .|. .. .||.|. ||.. |                                            |.|||||
SRGSLQDFMNNQRTIYQRLTEQTRFHEQECLQIMSDVCQGIQCMHQHQPRQDNATSRVNVDAVSMTYSDETAMLLEDTPLEMDMLSSNSAGSIPLIHRDI

KVGVENLLLT---------------------------------------------------------DKG-SVKLCDFGSATTQRLTP
|  .|| |.                                                          ...   |||||||... . |.
K--IENVLFCNLRRPSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSEDSEHNGIYKLCDFGSCCECIITI
Kinase AqueK171.AA Pkinase 238-389 24 4e-33 118.22 Pfam 1-159 (293) Show / Hide 
Range on Protein: 238-389
Range on HMM: 1-159/293
Sequence Identity: 24% (41 aa)

LKVKKVIAEGGYGFVFVAQDTSTGIDYALKRQIVASENIKAIKQ-----EITFLTQLSGHPHIIHFIGAASSKDPAGGSAEFLIVTELITGG----ELVD
......| .|..| |. ... .||. .|.|.  . .|. .  ..     ||  .  | .||.|. ....  .      . .  .|.|.  ||    .| |
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFED------KDHIYMVMEYCEGGLYVMDLFD

IVN---TRSL--SPHQVLRVFYETCQAIAHMHSQTPPIIHRDIKVGVENLLLTDKGSV----KLCDFGSA
..     ...  |.... ...|.........||.   |||||.|   ||.|. ..| .    |.||||.|
YISTWRHGCFYFSEWECKFYMYQILRGLEYCHSM--GIIHRDLK--PENILIDNNGHIDACVKICDFGLA
Kinase AqueK171.AA CAMK 243-390 17 1.6e-29 91.71 In-house 1-244 (425) Show / Hide 
Range on Protein: 243-390
Range on HMM: 1-244/425
Sequence Identity: 17% (43 aa)

VIAEGGYGFVFVAQDTSTG------------IDYALKR----QIV-------------------------ASENIKAIKQEITFLTQLSG------HPHI
.. .|..| |. .....|.              .| |     ..                            .. | ...||  . .|.|      ||.|
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IHFIGAASSKD---------PAGG-----SAEFLIVT---ELITGGEL----VDIVNTR----------------SLSPHQVLRVFYETCQAIAHMHSQT
|... .  ...                    .. .|.   |...||||     | .  .                 .. ... |.|   |.|....||. 
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

PPIIHRDIKVGVENLLLTDK-----------------GSVKLCDFGSAT
  |.|||.|   ||.||.|.                 . .|..||| |.
--IVHRDLK--PENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFAN
Kinase AqueK171.AA TKL 244-391 21 1.2e-25 89.3 In-house 1-203 (364) Show / Hide 
Range on Protein: 244-391
Range on HMM: 1-203/364
Sequence Identity: 21% (45 aa)

IAEGGYGFVFVAQDTS--------TGIDYALKRQIV-------------------------ASENIKAIKQEITFLTQLSG--HPHIIHFIGAASSKDPA
| .||.| |. ..           || | | |.  .                         . |. .. ..|.  . ..|   ||.|..|.|.. . .. 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

-------GGSAEFLIVTELITGGELVDIVNTRSLSPHQVLRVFYETCQAIAHMHSQT------PPIIHRDIKVGVENLLLTDKGS--------------V
       |.. .. ||.|.. || | ....     .|| .|  ..........||..      |||||||.|   .|.|. ...               .
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-----WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLK--SKNILVDENWTNVSNYMYNPNADWCC

KLCDFGSATT
|.|||| ...
KICDFGLSRF
Kinase AqueK171.AA CAMKL 238-393 24 2.8e-25 77.5 In-house 1-180 (297) Show / Hide 
Range on Protein: 238-393
Range on HMM: 1-180/297
Sequence Identity: 24% (48 aa)

LKVKKVIAEGGYGFVFVAQDTST-GIDYALKRQIVASENIKA------------------IKQEITFLTQLS--GHPHIIHFIGAA--SSKDPAGGSAE-
 .. |.. .|..| |  |....| |. .| |  |.  . |.                   |..||  . .|.  .||.||..      ...       . 
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIK--IIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEH-------DI

----FLIVTELITGGE--LVDIVNTRS-----LSPHQVLRVFYETCQAIAHMHSQTPPIIHRDIKVGVENLLLTDKGS--VKLCDFGSATTQR
    . .|.|.. |||  | | .  .      ...|.  | |   . |....||.   |.|||||   ||.||...|.  .|..||| .. .|
ETKKIYLVMEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHG--IVHRDIK--PENILLDENGNNNIKIIDFGFSNMYR
Kinase AqueK171.AA STE20 238-389 29 8.4e-23 80.36 In-house 1-164 (288) Show / Hide 
Range on Protein: 238-389
Range on HMM: 1-164/288
Sequence Identity: 29% (51 aa)

LKVKKVIAEGGYGFVFVAQDTSTGID----YALKRQIVAS-----ENIKAIKQEITFLTQLSGHPHIIHFIGAASSKDPAGGSAEFLIVTELITGGELVD
 .  ..| .|.|| |..| ...||      .| |.  . .     . .. |..|| .. |.  ||.|....|.   .|..    |  || |.  || | |
YELLEKIGQGSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNEQDEWEDIQKEISIMKQCK-HPNIVKYYGSYLKDDTC--DDELWIVMEYCGGGSLTD

IVN---TRS-------LSPHQVLRVFYETCQAIAHMHSQTPPIIHRDIKVGVENLLLTDKGSVKLCDFGSA
|..   ..        ..  |.  . .|..|. .. ||.   ||||||| .  | |||..|.|||.||| .
IMKHCMKCGKNHKGHPMNEEQIAYICREVLQGLDYLHSNH--IIHRDIKAD--NILLTEDGEVKLADFGVC
Kinase AqueK171.AA STE 238-390 22 2e-22 76.07 In-house 1-195 (359) Show / Hide 
Range on Protein: 238-390
Range on HMM: 1-195/359
Sequence Identity: 22% (46 aa)

LKVKKVIAEGGYGFVFVAQDTS---------------TGIDYALKRQIVAS------------------ENIKAIKQEITFLTQLSG-HPHIIHFIGAAS
..  ..| .|..| |. | .                 ||  .| |.  . .                  |... |..|| .. ...  ||.|....|.  
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

SKDP-AGGSAEFLIVTELITGGELVDIVNT-----RSLS----------PHQVLRVFYETCQA-IAHMHSQTPPIIHRDIKVGVENLLLTDKGSVKLCDF
 ...  .   |  |. |.. || | ||...     ..|.           .|. .. ......  .. ||.   |||||||    | ||     ||||||
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH--IIHRDIK--PANILL-----VKLCDF

GSAT
| ..
GVCG
Kinase AqueK171.AA Ciliate-E2 238-392 19 2.7e-21 69.84 In-house 1-206 (365) Show / Hide 
Range on Protein: 238-392
Range on HMM: 1-206/365
Sequence Identity: 19% (43 aa)

LKVKKVIAEGGYGFVFVAQDTSTGIDYA----------------LKRQIVASENI-----KAIKQEITFLT---------------QLSGHPHIIHFIGA
 |. |.| .|..| |. ... ... ..|                 | .|.| ...     ..|||||  .                ..  ||.|| .. .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

AS--SKDPAGGSAEFLIVTELITGGELVDIVNTRSLSP------------HQVLRVFYETCQ---------------AIAHMHSQTPPIIHRDIKVGVEN
    ...       . .|.|.. ||.| |. . ....              ........ .|               |. ..||. . |||||||   ||
FQEKDDN------NIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNN-IIHRDIK--PEN

LLLTDKGSVKLCDFGSATTQ
.|.     .|..||| .. .
ILF-----IKIIDFGLSKKY
Kinase AqueK171.AA S_TKc 238-533 15 2.1e-16 61.77 SMART 1-231 (231) Show / Hide 
Range on Protein: 238-533
Range on HMM: 1-231/231
Sequence Identity: 15% (53 aa)

LKVKKVIAEGGYGFVFVAQDTSTGIDYALKRQIVASENIKAIKQEITFLTQLSGHPHIIHFIGAASSKDPAGGSAEFLIVTELITG--GELVDIVNTRS-
 .. ..| .|..| |. .....||  .|.|.        . |..||  | .  .||.|......  .        .. .|.|.. |  |.| |.   |  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK--HHPNIVKLYDVFQD-------DHLYMVMEYCDGDLGDLFDYIKKRGR

------LSPHQVLRVFYETCQAIAHMHSQTPPIIHRDIKVGVENLLLTDKGSVKLCDFGSATTQRLTPDHSWSATQRGLREDENIKDTSNKVISSVQNPK
      ... .. ...|..|.|....||.   |||||.|   ||.||..   .|.||||.|.                                      
HGLRFPFPE-HARFYMYQICCALEYCHSH--GIIHRDLK--PENILLDE--HIKICDFGLARQL------------------------------------

QKSTDITYVTSR--------------------------ILVMSYPFEEGGVGRPNVLKEVAAYLEGTHPSQYLVFNLSGEQYDTDQLSGQVVDYEWPNRA
      |.. ..                           |.   ||.      .... ..                                        
-----TTFCGTPWYMAPEVLGYGKCKCDWWSCGCILYEMLCGYPPFP-----QMQMMFKKIG--------------------------------------

MPPLESLVELCRQLDSWLRADFKNVLV-------IHCK
 |.. .... | | |   |     .|            
SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK171.AA Pkinase_Tyr 238-366 21 1.6e-10 36.3 Pfam 1-137 (270) Show / Hide 
Range on Protein: 238-366
Range on HMM: 1-137/270
Sequence Identity: 21% (31 aa)

LKVKKVIAEGGYGFVFVAQDT----STGIDYALKRQ--IVASEN--IKAIKQEITFLTQLSGHPHIIHFIGAAS-SKDPAGGSAEFLIVTELITGGELVD
..  |.. || .| |. .  .    .|.|. | |       .|.  ...  .|.  ..||  ||.|. ..|. .  ..|     . .||.|.  .| | |
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPN----QIYIVMEYMPHGDLLD

IVNTR-----SLSPHQVLRVFYETCQAIAHMHSQTPPIIHRDI
   ..     .|.... |   .. ... .. .|.   .||||.
YLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKN--CIHRDL
Kinase AqueK171.AA TyrKc 238-531 14 1.8e-09 -69.51 SMART 1-280 (280) Show / Hide 
Range on Protein: 238-531
Range on HMM: 1-280/280
Sequence Identity: 14% (49 aa)

LKVKKVIAEGGYGFVFVAQDTSTGIDYALKRQIVASENIKAIKQEITFLTQL-SGHPHIIHFIGAASSK-------DPAGGSAEFLIVTELITGGELVDI
.. .|.. || .| |. .. .   |. | |     .  .... .|.  ...|   ||.|. ..|.....       .|       .||.|.  .| | | 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEP------LMIVMEYMPHGDLKDY

VNTRS--LSPHQVLRVFYETCQAIAHMHSQTPPIIHRDIKVGVENLLLTDKGSVKLCDFGSATTQRLTPDH--------SWSATQRGLRED---------
   .   |.. . |   .  ..  .. ||.  ..||||.     | |..... || .||| .   |   |.          ...... . .         
LRKHRPKLCMKDLLSFCWQIACGMEYLHSK--NCIHRDLA--ARNCLVGENHTVKISDFGLS---RDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAP

ENIKDT--SNK------------VISSVQNPK-------QKSTDITYVTSRILVMSYPFE----EGGVGRPNVLKEVAAYLEGTHPSQYLVFNLSGEQYD
| |..   . |            . .  | |         . ...     .   |  | .                                        
ECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS-----------------------------------

TDQLSGQVVDYEWPNRAMPPLESLVELCRQLDSWLRADFKNVLVIH
               .. . . .. . | . |   |  |...  . 
------------F-VCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase AqueK171.AA Pkinase_Tyr 372-387 56 0.64446 3.73 Pfam 141-156 (270) Show / Hide 
Range on Protein: 372-387
Range on HMM: 141-156/270
Sequence Identity: 56% (9 aa)

NLLLTDKGSVKLCDFG
| |.|... || ||||
NCLVTENNVVKICDFG