Gene AqueK175 (A.queenslandica)

AqueK175

Species: A.queenslandica
Alias: AqueK175
External Links:
Annotation:

Classification

Group: Other
Family: NEK
Subfamily: NEK-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
AqueK175.AA Protein None 322 None Fasta, JSON
AqueK175.kin_dom Protein Kinase Domain None 271 None Fasta, JSON

Protein domain

Protein domains of AqueK175.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc AqueK175.AA S_TKc 32-306 36 2.4e-83 284.1 SMART 1-231 (231) Show / Hide 
Range on Protein: 32-306
Range on HMM: 1-231/231
Sequence Identity: 36% (103 aa)

YELESKIGHGGFGSVYKVKEKKTKLIFAAKIFENNENNSQEIMLQAGINDKNVVKIHDVMSNEESLIMIMEYCEG--GNLFDWIKRNRRHDS---LNEKV
||.  |||.|.||.|||...|||. |.| ||    |.  .|| .    . .|.||..||. . ..| |.||||.|  |.||| ||...||     ..| .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-H

ILSMLYQICIAVHTCHCNKVIHRDLKPENILLDSNRQVKIGDFGVARKLNRSSIAKTFCGTPPYMAPELFLSYLGNTGGSHNALGYDS-KCDVWSIGCVL
. ...|||| |.  || ...|||||||||||||.  ..||.|||.||.|      .|||||| |||||..              ||.  |||.||.||.|
ARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL--------------GYGKCKCDWWSCGCIL

YDMSNDQSRFVYQLQFALGLDAARSPSNSINEKDITQLIDTDIPKDYTVVKKLLHKMLVRTPQERATLSDVLH---DTDLKKCL
| |   .  |                    ... . ..|          .| .. |.|.. |..| |  ..|.   |  .   .
YEMLCGYPPFP-------------------QMQMMFKKIG------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Pkinase AqueK175.AA Pkinase 32-228 38 1.6e-72 252.0 Pfam 1-205 (293) Show / Hide 
Range on Protein: 32-228
Range on HMM: 1-205/293
Sequence Identity: 38% (84 aa)

YELESKIGHGGFGSVYKVKEKKTKLIFAAKIFENNENNS---------QEIMLQAGINDKNVVKIHDVMSNEESLIMIMEYCEGG----NLFDWIKRNRR
|....||| |.||.||| ..|.|  |.| ||..  ...|         .|| . . .| .|.|...|.. .. .. |.|||||||     |||.|.. .|
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST-WR

HDSL--NEKVILSMLYQICIAVHTCHCNKVIHRDLKPENILLDSNRQV----KIGDFGVARK--LNRSSIAKTFCGTPPYMAPELFLSYLGNTGGSHN-A
| ..   |... ...|||. ..  || ...|||||||||||.|.| ..    ||.|||.|..  . ..| ..||||||.|||||.           .. .
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEV-----------IRGG

LGYDSKCDVWSIGCVLYDM
 .|..|.|.||.||.|| |
QYYGPKVDMWSCGCILYEM
Kinase AqueK175.AA CAMK 37-228 23 7.3e-70 224.07 In-house 1-327 (425) Show / Hide 
Range on Protein: 37-228
Range on HMM: 1-327/425
Sequence Identity: 23% (79 aa)

KIGHGGFGSVYKVKEKKTK------------LIFAAKIFE---------------------------------NNENNSQEIMLQAG-------INDKNV
..|.|.|| |.....|.|.              .|.|| .                                 . .|  .|| .          .. .|.
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VKIHDVMSN-------------------EESLIMIM---EYCEGG----NLFDWIKRNRR------------HDSLNEKVILSMLYQICIAVHTCHCNKV
.|...|. .                   .. ..|.|   |||.||     |||.|.....            .  ..|.    .  ||| ||| || ...
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

IHRDLKPENILLDSN-----------------RQVKIGDFGVARKLNRSS------------------------IAKTFCGTPPYMA-PELFLS------
.||||||||||||.|                  ..|| ||| |.|.....                          |||||||.||| ||....      
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

-YLGNTGGSHNALGYDSKCDVWSIGCVLYDM
 . . |  . .  .|. |||.||.|..|| |
QN-A-T--DEEKPYYGPKCDMWSCGVILYIM
Kinase AqueK175.AA AGC 32-228 21 1.3e-65 167.65 In-house 1-298 (395) Show / Hide 
Range on Protein: 32-228
Range on HMM: 1-298/395
Sequence Identity: 21% (67 aa)

YELESKIGHGGFGSVYKVKEK------KTKLIFAAKIFE-----------NNENNSQE------------IMLQAGIN----------DKNVVK-IHDVM
.|.   || |.|| || |..|       |. ..| |. .             |..  |                . .|            ..||  |   
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

SNEES--LIMIMEYCE---------GGNLFDWIKRNR-RHDSLNEKVILSMLYQ-------ICIAVHTCHC-NKVIHRD-LKPENILLDSNRQVKIGDFG
 ...   | ..|||..         ||  . .....| .  ...|...  .. .       |. |..  |  ...|||| |||||||||..  .|. |||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

VARKLNRSS---------------------------------------------------IAKTFCG--TPPYMAPELFLSYLGNTGGSHNALGYDSKCD
 . .....                                                     ..||||  || ||||| .               |.  ||
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL---------------YGKACD

VWS--IGCVLYDM
 ||   ||..| |
WWSFGLGCLMYEM
Kinase AqueK175.AA Ciliate-E2 32-297 25 4.4e-62 211.9 In-house 1-360 (365) Show / Hide 
Range on Protein: 32-297
Range on HMM: 1-360/365
Sequence Identity: 25% (99 aa)

YELESKIGHGGFGSVYKVKEKKTK-----------------------LIFAAKIFENN--ENNSQEIMLQAGIN----------------DKNVVKIHDV
|..  ||| |.||||||.| .|..                        |.| ||...|  |. .||| .   ||                 .|..|....
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

MS--NEESLIMIMEYCEGGNLFDWIK---RNRRHD-----SLNEKVILSMLYQIC---------------IAVHTCHCNK-VIHRDLKPENILLDSNRQV
    ..... ..||||.||.|||.||    .| |      ...|| |. . .||.                |.. .| .. .||||.||||||.     .
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KIGDFGVARKLNRS--------------------------------SIAKTFCGTPPYMAPELFL--SYLGNTGGSHNALGYDSKCDVWSIGCVLYDMSN
|| ||| ..|.. .                                 ...|.||||.||||| .   .| ..     .  ||| |||.||.|..|| |  
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQ----QKQKGYDYKCDIWSLGVILYEMLF

DQSRFVYQLQFALGLDAARSPSNSINEKDITQLIDTDIP-----------------KDYTVVKKLLHK----MLVRTPQERAT-LSDVL
 .  |                     .. . . || . |                 |    .| |. |    ||.. |..| |  ...|
GKPPF--------------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQIL
Kinase AqueK175.AA CAMKL 32-226 31 1.2e-59 188.95 In-house 1-227 (297) Show / Hide 
Range on Protein: 32-226
Range on HMM: 1-227/297
Sequence Identity: 31% (75 aa)

YELESKIGHGGFGSVYKVKE-KKTKLIFAAKIFE-----NNENNSQ---------------EIMLQAGIN---DKNVVKIHDVMSNEES------LIMIM
|...  .|.|.|| |   .  . |.   | || .     |......               || ..  .|    .|..|...|. ..|       . ..|
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYCEGGN--LFDWIKRNRRHD-SLNEKVILSMLYQICIAVHTCHCNKVIHRDLKPENILLDSNR--QVKIGDFGVARKLNR-----SSIAKTFCGTPPYM
|||.||.  |||.|......  .. |.    .  ||. ||. || ....|||.||||||||.|   ..|| ||| . .  .         |||||.||||
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

APELFLSYLGNTGGSHNALGYD-SKCDVWSIGCVLY
|||.|..         |   ||  | |.||.| .||
APEIFQG---------NNKPYDGPKVDIWSCGVILY
Kinase AqueK175.AA Ciliate-E2-Unclassified 32-297 23 1.8e-56 193.89 In-house 1-347 (352) Show / Hide 
Range on Protein: 32-297
Range on HMM: 1-347/352
Sequence Identity: 23% (87 aa)

YELESKIGHGGFGSVYKVKEKKTKLIFAAKIFENNENNSQEIMLQA--------GINDKN----------------------VVKIHDVMSNEESLIMIM
|..  .||.||||.|||...||.|...| |.   . ...| ....          .| |.                      .|| ...  ... ....|
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM

EYCEGGNLFDWIK-------------RNRRHDS-LNEKVIL-----SMLYQICIAVHTCHCNK-VIHRDLKPENILLDSNR---QVKIGDFGVARKLN--
||||||.|...||             .|....  . |. ..      ...||. .   .| .. .||||.||||||.|.|    ..|| ||| ..|..  
EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQN

--------------RSSIAKTFCGTPPYM----APELFLS-YLGNTGGSHNALGYDSKCDVWSIGCVLYDMSNDQSRFVYQLQ--------------FAL
              .. ...|||||| ||    |||.. .   ...           |||.|| |..|| |   . .  |. .              .  
NNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKA--------YKCDIWSLGVILYEMLFGY-YPFYDNNCEQHQQLITQWINNA--

GLDAARSPSNSINEKDITQLIDTDIPKDYTVVK-------------------KLLHKMLVRTPQERATLSDVL
               .. ||..  . |.. . |                   .||.|||.  | .| |....|
---------------YRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQIL
Kinase AqueK175.AA ULK 32-228 28 1.2e-55 191.18 In-house 1-249 (329) Show / Hide 
Range on Protein: 32-228
Range on HMM: 1-249/329
Sequence Identity: 28% (73 aa)

YELESKIGHGGFGSVYKVKEKKTK----LIFAAKI-----FENNENN----------SQEIMLQAGIN----DKN----VVKIHDVMSNEES--LIMIME
|.|  ..|.| || ||| . ||||     ..|.|.     . ...|.           .|| ..  ..     ||    .|| .|.  .  .  . .|||
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

YCEGGNLFDWIKRNRR-------HDSLNEKVILSMLYQICIAVHTCHCNKVIHRDLKPENILLDSNR------------QVKIGDFGVARKLNRS----S
||.||.|.. ||.|..       .  |.|. ... ..||. .    | ...||||.||.|||.. .             ..||.||| |.... .     
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

IAKTFC------GTPPYMAPELFLSYLGNTGGSHNALG----YD-SKCDVWSIGCVLYDM
...|.       ||| ||||... .           .|    |. .|||.||.||..| |
MMMTCVNEKRLCGTPLYMAPQILQG-----------QGEQKPYYDYKCDIWSLGCIFYEM
Kinase AqueK175.AA STE 32-225 27 1.6e-55 190.75 In-house 1-258 (359) Show / Hide 
Range on Protein: 32-225
Range on HMM: 1-258/359
Sequence Identity: 27% (75 aa)

YELESKIGHGGFGSVYKVKEKK---------------TKLIFAAKIFE----------------------NNENNSQEIMLQAGIN--DKNVVKIHDVMS
.|. .|||.|.||.||| . .|               |. |.| |. .                      . ..  .|| .    |   .|.|| ..   
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

NE-------ESLIMIMEYCEGGNLFDWIKRN-RRHDSLN----------EKVILSMLYQICIA-VHTCHCNKVIHRDLKPENILLDSNRQVKIGDFGVAR
.|       ..| ..|||..|| | | ||..  . ..||          |..|  ...||. .  .  | ...||||.|| ||||     ||. ||||. 
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

KLNR-----------------SSIAKTFCGTPPYMAPELFLS----YLGNTGGSHNALGYDSKCDVWSIGCVL
.|.                  ..  .||.||| .||||  .     .           ||| |||.||.||..
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGR---------DKGYDTKCDIWSLGCTI
Kinase AqueK175.AA ULK 32-228 28 3.6e-55 189.6 In-house 1-245 (324) Show / Hide 
Range on Protein: 32-228
Range on HMM: 1-245/324
Sequence Identity: 28% (72 aa)

YELESKIGHGGFG-SVYKVKEKKT---KLIFAAKIFE-----NNENN----------SQEIMLQAGIN---DKN--VVKIHDVMSNEES--LIMIMEYCE
|.|  ..|.| ||  ||| . |||   . ..|.|. .     ...|.           .|| ..  ..    .|  .|| .|.  .  .  . .|||||.
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

GGNLFDWIKRNRR------HDSLNEKVILSMLYQICIAVHTCHCNKVIHRDLKPENILLDSNR------------QVKIGDFGVARKLNRSSIAKTFC--
||.|.. ||.|..      .  |.|. ... ..||| .    | ...||||.||.|||.  .             ..||.||| |....  . ... |  
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

--------GTPPYMAPELFLSYLGNTGGSHNALG----YD-SKCDVWSIGCVLYDM
        ||| ||||... .           .|    |. .|||.||.||..| |
CVNEKRIKGTPLYMAPQILQG-----------QGEQKPYYDYKCDIWSLGCIFYEM
Kinase AqueK175.AA NEK 94-228 37 2.2e-49 170.39 In-house 76-217 (286) Show / Hide 
Range on Protein: 94-228
Range on HMM: 76-217/286
Sequence Identity: 37% (57 aa)

EE--SLIMIMEYCE-GGNLFDW---IKRNR-RHDSLNEKVILSMLYQICIAVHTCHCN-----KVIHRDLKPENILLDSNRQ----VKIGDFGVARKLNR
|.  .|. .||||| ||.|..    ||... ... . |..|. ...|.|.|.. .| .     |..|||.|| || |..|.     |||||||... ||.
EQNNCLCIVMEYCEGGGDLYQKIKSIKKQKQKGKYFEEEQIWDWFIQMCLALKYMHDRKGPQRKILHRDIKPQNIFLTKNNNDYHNVKIGDFGISKVLNH

S-SIAKT-FCGTPPYMAPELFLSYLGNTGGSHNALGYDSKCDVWSIGCVLYDM
. . |.| . ||| ||.||..           .  .|..|.|.||.||||| |
TTDMAYTTQVGTPYYMSPEVC-----------QNKPYNNKSDIWSLGCVLYEM
Kinase AqueK175.AA MARK 32-226 36 2.2e-48 156.34 In-house 1-197 (262) Show / Hide 
Range on Protein: 32-226
Range on HMM: 1-197/262
Sequence Identity: 36% (78 aa)

YELESKIGHGGFGSVYKVKEKKTKLIFAAKIFE---NNE-NN----SQEIMLQAGINDKNVVKIHDVMS--NEES-LIMIMEYCEGGNLFDWIKRN--RR
|..   ||||... |...  |.|.  .| || |    |. ..      || .   .. .|..| ..|.   .|.  . .||||..||.|.|.||    .|
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

HDSLNEKVILSMLYQICIAVHTCHCNKVIHRDLKPENILLDSNR--QVKIGDFGVARKLNRSSIAKTFCGTPPYMAPELFLSYLGNTGGSHNALGYD-SK
   | |.    .  ||. ||. || . ..|||.||||||.|.|.  ..|| ||| ... .  .  .||||||||||||.||.             ||  |
---LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLK-----------KPYDGPK

CDVWSIGCVLY
 |.|| | |||
VDIWSLGVVLY
Kinase AqueK175.AA Pkinase_Tyr 82-226 27 1.3e-16 56.84 Pfam 64-205 (270) Show / Hide 
Range on Protein: 82-226
Range on HMM: 64-205/270
Sequence Identity: 27% (43 aa)

KNVVKIHDVMS-NEES--LIMIMEYCEGGNLFDWIKRN-RRHDSLNEKVILSMLYQICIAVHTCHCNKVIHRDLKPENILLDSNRQVKIGDFGVARKL--
.|.|. . | .  .|.  ....|||...|.| |  ...    ..|. | .|.| .||. .    . .. |||||   |.|...|..|||.||| || .  
PNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYN

-----NRSSIAKTFCGTPPYMAPELFLSYLGNTGGSHNALGYDSKCDVWSIGCVLY
       .. .| .    . |||| .  .            . .| |||| | ...
DDYYYRKRGGGK-LP--IKWMAPECINYGK-----------FTTKSDVWSFGVLMW
Kinase AqueK175.AA TyrKc 32-306 22 8.4e-15 16.65 SMART 1-280 (280) Show / Hide 
Range on Protein: 32-306
Range on HMM: 1-280/280
Sequence Identity: 22% (71 aa)

YELESKIGHGGFGSVYKVKEKKTKLIFAAKIFENNENNSQEIMLQA----GI--NDKNVVKIHDVMSNE-------ESLIMIMEYCEGGNLFDWIKRNRR
 .|. |.|.| || ||| . |   .  | |   ..    ...|  |     .  . .|.|... | . .       | | ..|||...|.| | ....|.
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP

HDSLNEKVILSMLYQICIAVHTCHCNKVIHRDLKPENILLDSNRQVKIGDFGVARKLNRS--------SIAKTF--CGT--PPY--MAPELFLSYLGNTG
.  |. |  ||. .||.      | ...|||||   |.|...|..|||.||| .|..            . |.   .|    |.  |||| .        
K--LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI--------

GSHNALGYDSKCDVWSIGCVLYDMSNDQSRFVYQLQFALGLDAARSPSNS-----INEKDITQLIDTD----IPKD---------YTVVKKLLHKMLVRT
   |   . .| |||| | ... .            | .|     .|        .. ... .....     .|..          . . ..  .   . 
---NYGKFTTKSDVWSFGVCMWEI------------FTYG----QQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHED

PQERATLSDVLHDTDLKKCL
| .| | |..      ..|.
PEDRPTFSEI------HECF
Kinase AqueK175.AA NEK 32-61 40 2.4e-08 25.9 In-house 1-35 (286) Show / Hide 
Range on Protein: 32-61
Range on HMM: 1-35/286
Sequence Identity: 40% (14 aa)

YELESKIGHGGFGSVYKVKEKKTKLI-----FAAK
||.  ||| | ||.||||. |... .     .. |
YEIIKKIGQGSFGKVYKVRRKSDGKHLVEKLYVWK
Kinase AqueK175.AA CAMKL 275-302 25 4.5e-05 11.96 In-house 270-297 (297) Show / Hide 
Range on Protein: 275-302
Range on HMM: 270-297/297
Sequence Identity: 25% (7 aa)

VKKLLHKMLVRTPQERATLSDVLHDTDL
.. |..|||.. | .|.|. ... .  .
CRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase AqueK175.AA MARK 276-302 22 0.000386 9.62 In-house 236-262 (262) Show / Hide 
Range on Protein: 276-302
Range on HMM: 236-262/262
Sequence Identity: 22% (6 aa)

KKLLHKMLVRTPQERATLSDVLHDTDL
..|....|.  | ||.|..... .  .
RNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase AqueK175.AA CAMK 275-299 36 0.002907 5.57 In-house 398-422 (425) Show / Hide 
Range on Protein: 275-299
Range on HMM: 398-422/425
Sequence Identity: 36% (9 aa)

VKKLLHKMLVRTPQERATLSDVLHD
.| |. |||.. |..|.|....| .
CKDLIRKMLQVDPEKRMTIEQCLNH
Kinase AqueK175.AA ULK 251-302 17 0.060142 2.69 In-house 255-329 (329) Show / Hide 
Range on Protein: 251-302
Range on HMM: 255-329/329
Sequence Identity: 17% (13 aa)

P----SNSINEKDITQLID-------------TDIPKD------YTVVKKLLHKMLVRTPQERATLSDVLHDTDL
|     |. ... |..||.             ...|||         .| |. .||.. . .| .  ....   .
PFYAWFNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQISPECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase AqueK175.AA Pkinase_Tyr 32-48 47 0.248788 5.13 Pfam 1-17 (270) Show / Hide 
Range on Protein: 32-48
Range on HMM: 1-17/270
Sequence Identity: 47% (8 aa)

YELESKIGHGGFGSVYK
 ..  |.|.| ||.|||
ITFGKKLGEGAFGEVYK
Kinase AqueK175.AA Pkinase 276-299 25 0.586351 4.47 Pfam 267-290 (293) Show / Hide 
Range on Protein: 276-299
Range on HMM: 267-290/293
Sequence Identity: 25% (6 aa)

KKLLHKMLVRTPQERATLSDVLHD
|... ..| . |..| |  ..|..
KDFIKWCLCKDPKKRPTAEQILQH