Gene AqueK176 (A.queenslandica)

AqueK176

Species: A.queenslandica
Alias: AqueK176
External Links:
Annotation:

Classification

Group: Other
Family: NEK
Subfamily: NEK1

Sequence

Name Sequence Type Origin Length Description Download
AqueK176.AA Protein None 1125 None Fasta, JSON
AqueK176.kin_dom Protein Kinase Domain None 255 None Fasta, JSON

Protein domain

Protein domains of AqueK176.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase AqueK176.AA NEK1 4-258 61 3.4e-185 621.54 In-house 1-276 (276) Show / Hide 
Range on Protein: 4-258
Range on HMM: 1-276/276
Sequence Identity: 61% (170 aa)

YTRIRKIGEGSYGRALLVKGRQDGRQYVIKVINLSKMDRRGREEARREVKVLSQMKHPNIVSYKDSFEETGS--LYIVMDYCDGGDLYKHINAQ--RGRL
|..|..|||||.|.|.||| . ||..|||| ||..|| .  |||...||..|. |||||||.||.|||| |.  |||||.|||||||.. ||.|  .| |
YHYIKQIGEGSFGKAWLVKHKEDGQHYVIKEINVMKMQEKEREESMNEVAILAKMKHPNIVKYKESFEENGCGILYIVMEYCDGGDLMQKINRQKRKGKL

FPEDQILNWFVQLCLALKHVHDRKILHRDIKSQNVFLT--KRG---------------VVKLGDFGIARVLNSTVELARTCIGTPYYLSPEICENRPYNN
|.||||..||.|.||||.|.||||||||||||||.|||  | |               .||||||||||.||.|.|.|.||||||||||||||.|.||||
FSEDQIMHWFCQICLALNHIHDRKILHRDIKSQNIFLTISKNGMGSGSGSGSSNDSIPLVKLGDFGIARMLNHTMEYACTCIGTPYYLSPEICQNKPYNN

KSDIWALGCVLYEMATLRHAFEAGNMRNLIVKIVRGSYPPLSSQYSRNLRSLVDSCLKNAPRDRPSINSILRLPFI
|||||.|||||||  || |.|||.|. ||. ||..|.|||... ||. |.||| . .|  ||.|||.|.||  |||
KSDIWSLGCVLYELCTLKHPFEANNWKNLVLKICQGTYPPIPPHYSYELQSLVSQMFKRNPRHRPSVNQILERPFI
Kinase AqueK176.AA NEK 4-258 51 2.7e-169 568.7 In-house 1-286 (286) Show / Hide 
Range on Protein: 4-258
Range on HMM: 1-286/286
Sequence Identity: 51% (147 aa)

YTRIRKIGEGSYGRALLVKGRQDGRQ-----YVIKVINLSKMDRRGREEAR-REVKVLSQMKHPNIVSYKDSFEETG--SLYIVMDYCD-GGDLYKH---
|..|.|||.||.|.. .|. ..||..     ||.| ||...|... ...|   ||..|.|.||||||.|.|||.| .  .|.|||.||. |||||..   
YEIIKKIGQGSFGKVYKVRRKSDGKHLVEKLYVWKKINMGNMSEKEKQNAQNNEVRILKQLKHPNIVKYYDSFIEEQNNCLCIVMEYCEGGGDLYQKIKS

INAQR--GRLFPEDQILNWFVQLCLALKHVHDR-----KILHRDIKSQNVFLTKRGV----VKLGDFGIARVLNSTVELART-CIGTPYYLSPEICENRP
|. |.  | .|.|.||..||.|.|||||..|||     ||||||||.||.||||..     ||.|||||..|||.|...|.| ..|||||.|||.|.|.|
IKKQKQKGKYFEEEQIWDWFIQMCLALKYMHDRKGPQRKILHRDIKPQNIFLTKNNNDYHNVKIGDFGISKVLNHTTDMAYTTQVGTPYYMSPEVCQNKP

YNNKSDIWALGCVLYEMATL--RHAFEAG--NMRNLIVKIVRG-SYPPLSSQ--YSRNLRSLVDSCLKNAPRDRPSINSILRLPFI
||||||||.||||||||.||  .|.|||   || .|..||..|  |||..|.  ||. |..|. ..|.  | .|||.|.|| .|||
YNNKSDIWSLGCVLYEMCTLKPKHPFEAWDMNMPSLYMKIMKGPQYPPIPSHRMYSQDLQNLISQMLQKDPEQRPSCNQILEMPFI
Kinase AqueK176.AA NEK8 4-258 42 2.7e-147 423.64 In-house 1-278 (278) Show / Hide 
Range on Protein: 4-258
Range on HMM: 1-278/278
Sequence Identity: 42% (119 aa)

YTRIRKIGEGSYGRALLVKGRQDG--RQYVIKVINLSKMDRRGREEARREVKVLSQMKHPNIVSYKDSFEETGSLYIVMDYCDGGDLYKHINAQRG-RLF
|.||| .| |. | . |  .. |.   . ..| ||.. |. ..|  |  |. |||   ||||.|| |.|.| ..| |.| |.||| ||  |. |..  ..
YERIRVVGRGAFGICWLYRRKEDQSHHLVIWKQINMHRMSEKERQMAQNEIQVLSMLQHPNIISYYDHFMEDNTLMIEMEYADGGTLYQMIQHQQNKLFE

PED----------------QILNWFVQLCLALKHVHDRKILHRDIKSQNVFLTKR-GVVKLGDFGIARVLNSTVELA--RTCIGTPYYLSPEICENRPYN
.|                 .||  |.| |.|. |.|.  |||||.| ||.|.|.. .|||.|||||. ..|.    .  .| .|||||.|||.|| .|||
EERQLKQVNHCFNIYFNEQMILWYFFQMCSAVHHMHQHNILHRDLKTQNIFMTRHRMVVKIGDFGISKIMNTKYHMQTTKTVVGTPYYMSPEMCEGKPYN

NKSDIWALGCVLYEMATLRHAFEAGNMRNLIVKIVRG-SYPPLSSQYSRNLRSLVDSCLKNAPRDRPSINSILRLPFI
.|||.||||||||||..|. |||| |  .|..||...  | |.|..||  .|.|| .||.  |  |||   |.  | .
QKSDMWALGCVLYEMCCLKRAFEASNLPALVWKIMQCRAYEPISDHYSNEMRMLVHNCLQQDPEQRPSASQIMAMPLC
Kinase AqueK176.AA NEK4 4-258 50 5.4e-136 458.09 In-house 1-257 (257) Show / Hide 
Range on Protein: 4-258
Range on HMM: 1-257/257
Sequence Identity: 50% (129 aa)

YTRIRKIGEGSYGRALLVKGRQDGRQYVIKVINLSKMDRRGREEARREVKVLSQMKHPNIVSYKDSFEETGS--LYIVMDYCDGGDLYKHINAQRGRLFP
|  .. .| ||||   ||. |.|..|||.| ..| . .|| | .| .|...|||.||||||.||.|.|      ||||| .|.|||||.    |.. . .
YCHMKVVGKGSYGEVWLVRHRRDKKQYVMKKMFLKNASRRERKAAEHEAQLLSQLKHPNIVEYKESWEIENGQFLYIVMGFCEGGDLYRKLKQQKNQFLE

EDQILNWFVQLCLALKHVHDRKILHRDIKSQNVFLTKRGVVKLGDFGIARVLNSTVELARTCIGTPYYLSPEICENRPYNNKSDIWALGCVLYEMATLRH
| |...||||  .||   |...||||| | ||.||||. ..|.|||||.||||   ..|.| ||||||.|||.  ||||. |||||.||| .|||.||.|
EYQVVEWFVQIAMALQYMHEKHILHRDLKTQNIFLTKKNIIKIGDFGISRVLNNHCDMAKTMIGTPYYMSPECFGNRPYDYKSDIWSLGCCVYEMITLKH

AFEAGNMRNLIVKIVRGSYPPLSSQYSRNLRSLVDSCLKNAPRDRPSINSILRLPFI
||.| .|  || .|. |  ||.. .|| .|  ||   |.  | .|||| .|.. |.|
AFDAKDMNSLIYQIIQGQPPPMPPNYSQDLQNLVYQMLEKQPTKRPSIFDIFQMPYI
Kinase AqueK176.AA S_TKc 4-258 32 4.4e-99 336.39 SMART 1-231 (231) Show / Hide 
Range on Protein: 4-258
Range on HMM: 1-231/231
Sequence Identity: 32% (87 aa)

YTRIRKIGEGSYGRALLVKGRQDGRQYVIKVINLSKMDRRGREEARREVKVLSQMKHPNIVSYKDSFEETGSLYIVMDYCDG--GDLYKHINAQRGRL--
|. .||||.|..|.  ... . .||.. ||.|.         | .|||...|.. .||||| ..|.|.. ..||.||.||||  |||...|  ....   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--FPEDQILNWFVQLCLALKHVHDRKILHRDIKSQNVFLTKRGVVKLGDFGIARVLNSTVELARTCIGTPYYLSPEICENRPYNN-KSDIWALGCVLYEM
  ||| ..  .. |.|.||.. |...|.|||.| .|..|..  ..|..|||.||.|       .|..|||.|..||..   .|.  |.|.|..||.||||
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM

ATLRHAFEAGNMRNLIVKIVRGSYPPLSSQYSRNLRSLVDSCLKNAPRDRPSINSILR-------LPFI
.. .  |.  .|  .. ||.           |. ...... ||.  |..||..  .|.        |..
LCGYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK176.AA Pkinase 4-258 28 1.7e-90 311.78 Pfam 1-293 (293) Show / Hide 
Range on Protein: 4-258
Range on HMM: 1-293/293
Sequence Identity: 28% (83 aa)

YTRIRKIGEGSYGRALLVKGRQDGRQYVIKVINLSKMDRRGREEARR--EVKVLSQMKHPNIVSYKDSFEETGSLYIVMDYCDGG----DLYKHINAQRG
|...||||.||.|.  . . . .|.....|.|.... .   ....||  |....  ..||||| ..|.||. ...|.||.||.||    ||. .| ..|.
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

RLF--PEDQILNWFVQLCLALKHVHDRKILHRDIKSQNVFLTKRGVV----KLGDFGIARVL-NSTVELARTCIGTPYYLSPEICE-NRPYNNKSDIWAL
. |  .|... ... |.. .|.. |...|.|||.|..|... ..|..    |..|||.|... .   . . |  |||.|..||..  ...|  |.|.|..
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GCVLYEMATLRHAFEAG----NMRNLIVKIVRGSYPPLSSQYS-----------------------RNLRSLVDSCLKNAPRDRPSINSILRLPFI
||.||||.. |  |       | .. ...|.|  .|||.....                       .........||.  | .||..  ||  |..
GCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase AqueK176.AA NEK-Unclassified 4-258 38 1.2e-89 297.02 In-house 1-258 (258) Show / Hide 
Range on Protein: 4-258
Range on HMM: 1-258/258
Sequence Identity: 38% (100 aa)

YTRIRKIGEGSYGRALLVKGRQDGRQYVIKVINLSKMDRRGREEARREVKVLSQMKHPNIVSYKDSFEETGSLYIVMDYCDGGDLYKHINAQRGR--LFP
| .|  .| |  |   ||.     |  | ..    |  .|        . .|||..|| || | ||| |   |.   ||||||.| . |  .|..   | 
YDKITTLGQGGGGAVYLVRHQISKRHLVQQISKRKKKKKR-----QNKIIILSQLRHPHIVTYHDSFFENAKLFYTQDYCDGGNLDRRIQKHRKKNEPFD

EDQILNWFVQLCLALKHVHDRKILHRDIKSQNVFLTKRGVVKLGDFGIARVLNSTVELARTCIGTPYYLSPEICENRPYNNKSDIWALGCVLYEMATLRH
|  |  |..|.  |.  .| |||.||| | ||.|||.  .| .|||||.|... |.. ||||.||. ..|||.|.  ||||.||.|.|||..|||.|   
EGRIMQWCIQMIMAVQYIHQRKIIHRDLKPQNIFLTDDDTVSMGDFGISRIMDHTRDKARTCVGTMCWMSPEVCQDQPYNNRSDVWSLGCIIYEMCTCEP

AFEAGNMRNLIVKIVRGSY------PPLSSQYSRNLRSLVDSCLKNAPRDRPSINSILRLPFI
.| . ||  .  ||...         | |. ||  |  ..   |.  .  |||   |. ...|
FFDTHNMGEVYMKIKQDDNRLEEALEPVSKTYSTDLQQVIRFMLRRNFQQRPSATEIVEQDYI
Kinase AqueK176.AA NEK2 4-258 34 9.6e-77 257.93 In-house 1-319 (319) Show / Hide 
Range on Protein: 4-258
Range on HMM: 1-319/319
Sequence Identity: 34% (110 aa)

YTRIRKIGEGSYGRALLVKGRQDGRQYVIKVINLSKMDRRGREEARREVKVLSQMKHPNIVSYKDSF--EETGSLYIVMDYCDGGDL---YKHINAQRGR
|     ||.||.||   |.   ||.  | | |.  .|.   .     |. .|.| |||||| | |    ... .||||| || ||||    |.   .| .
YEVLYTIGNGSFGRCRKVRRKSDGKILVWKEICYGHMQEKECQMLVSECNILRQLKHPNIVRYYDWIIDRQNSTLYIVMEYCEGGDLSQMIKKCRKERQY

LFPEDQILNWFVQLCLALKHVHD---------------------RKILHRDIKSQNVFLTKRGV------------------------------------
. .|  |.  . |||.||. .|                      . |||||||  |.||   .                                     
M-EEEFIWRIMFQLCTALQECHNGVELPTLTTIYDRMKPRIDGKHTILHRDIKPANIFLDYDHNDYNINEQVDGHEEVNSNYYRDHRVNSGKRGSPMDYS

---VKLGDFGIARVLNSTVELARTCIGTPYYLSPEICENRPYNNKSDIWALGCVLYEMATLRHAFEAGNMRNLIVKIVRGSYPPLSSQYSRNLRSLVDSC
   ||||||| ||.||     | | .||||| |||  . ..|| |||||..||..|||..|.  |.| |   | .||  | . .. .|||| |  .. . 
QVVVKLGDFGLARMLNHDTSFAHTFVGTPYYMSPEQMHGQKYNEKSDIWSVGCLIYEMCALHPPFQATNQAQLQEKIKQGHFRRIPYQYSRHLNEIIHFM

LKNAPRDRPSINSILRLPFI
..  .. ||||. ||. |.|
INVDHYHRPSIEEILQHPQI
Kinase AqueK176.AA CAMK 9-258 18 2.4e-75 242.04 In-house 1-425 (425) Show / Hide 
Range on Protein: 9-258
Range on HMM: 1-425/425
Sequence Identity: 18% (79 aa)

KIGEGSYGRALLVKGRQDG------------RQYVIKVINLSKMD--------------------------RRGREEARREVKVLSQ-------MKHPNI
..|.||.|   |.. ....            ... ||.|. .|..                           . |.. |||......       ..||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VSYKDSFEE-----------TGS---------LYIVM---DYCDGG----DLYKHINAQRG-------------RLFPEDQILNWFVQLCLALKHVHDRK
..  . .|            | |         .|.||   .||.||    ||. .| ....             . |.|..   .| |.| |... |...
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

ILHRDIKSQNVFLTKR-----------------GVVKLGDFGIARVLNSTV-----------------------ELARTCIGTPYYLS-PEICEN-----
| |||.|  |. |...                 . .|. ||| |.....                         .. .|. |||.| . ||. .      
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

---------RPYNNKSDIWALGCVLYEMATLRHAFEAG-------------NMRNLIVKIVRGSYPPLSSQYSR-----------------------NLR
         ..|. |.|.|..|..|| | . .  |..              |...|  || .| |   ... |                          .
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

SLVDSCLKNAPRDRPSINSILRLPFI
.|. ..|.  | .|..|  .|. |..
DLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase AqueK176.AA NEK11 4-258 40 1.5e-70 240.7 In-house 1-259 (259) Show / Hide 
Range on Protein: 4-258
Range on HMM: 1-259/259
Sequence Identity: 40% (104 aa)

YTRIRKIGEGSYGRALLV---KGRQDGRQYVIKVINLSKMDRRGREEARREVKVLSQMKHPNIVSYKDSFEETGSLYIVMDYCDGGDLYKHINA--QRGR
|    |.| ||.|   ||   | ..     |.| |    .       |  | ..||...|| || .  || |     |. .||.| ||  .|    | |.
YVLQQKLGSGSFGTVYLVSDKKAKRGEELKVLKEISVGELNPNETVQANVEAQLLSRLHHPAIVRFHASFMEQDNFCIITEYCEGRDLDYRIQEYKQAGK

LFPEDQILNWFVQLCLALKHVHDRKILHRDIKSQNVFLTKRGVVKLGDFGIARVLNSTVELARTCIGTPYYLSPEICENRPYNNKSDIWALGCVLYEMAT
.||| ||. ||.|| |    .|.|.|||||.||.|.|| |  ..|.||||..|.|    .|| |  ||| |.|||      |  |||||.| |.||||  
IFPENQIIEWFIQLLLGVDYMHERRILHRDLKSKNIFL-KNNLLKIGDFGVSRLLMGSCDLATTLTGTPHYMSPEALKHQGYDTKSDIWSLACILYEMCC

LRHAFEAGNMRNLIVKIVRGSYPPLSSQYSRNLRSLVDSCLKNAPRDRPSINSILRLPFI
. |||   |   ....|| |  | |   | | | ..... |   |  |||   ||. |..
MDHAFAGSNFLSIVLNIVEGDTPSLPDRYPRELNTIMERMLNKNPSLRPSAIDILKIPYM
Kinase AqueK176.AA STE 4-258 24 1.3e-69 237.57 In-house 1-359 (359) Show / Hide 
Range on Protein: 4-258
Range on HMM: 1-359/359
Sequence Identity: 24% (91 aa)

YTRIRKIGEGSYG---RALLVK-------GRQ-----DGRQYVIKVINLSKMD---------------RRGREEARREVKVLSQMK--HPNIVSYKDSFE
...|.|||.|..|   .|. .|       |..      |. . ||..||.. .                  ...  .|.|......  ||||| | ....
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

ETG-------SLYIVMDYCDGGDLYKHINAQRGRLFP------------EDQILNWFVQLCLA-LKHVHDRKILHRDIKSQNVFLTKRGVVKLGDFGIAR
  |       .|.|.| |.||| | . |.   |...|            |.||    .|.. . |.. |. .| |||||..|..|     ||| |||.. 
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

VLNS----------------TVELARTCIGTPYYLSPEICEN------RPYNNKSDIWALGCVLYEMATLRHAFEA-GNMRN---------------LIV
 |..                ...   |..||| . .||. ..       .|. |.||| |||.. |||| .. .    .||.               .. 
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQL-

KIVRGSYPPLSS-------------------QYSRNLRSLVDSCLKNAPRDRPSINSILR--LPFI
.|| |  ||| .                   ..| ...  .. ||.  |..||. .  |.   |||
CIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase AqueK176.AA ULK 4-258 25 3.1e-67 229.69 In-house 1-329 (329) Show / Hide 
Range on Protein: 4-258
Range on HMM: 1-329/329
Sequence Identity: 25% (86 aa)

YTRIRKIGEGSYGRALLVKGR---QD---GRQYVIKVINLSKMDRRGREEA--------RREVKVLSQMK--------HPNIVSYKDSFEETGS--LYIV
|  ....|.||.|     |||   ..   . ....|.| ..||..   |          ..|.|.. ..|        ||||| ..| ||.. .  .||.
YCLNHCLGKGSFG--KVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYII

MDYCDGGDLYKHINAQRG--------RLFPEDQILNWFVQLCLALKHVHDRKILHRDIKSQNVFLTKR------------GVVKLGDFGIARVLNST---
|.||.|||| . |. ...        . ..|..... | |.. ..|. |...| ||||| ||. ...             ||.|..||| |.....    
MEYCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNME

VELARTCI------GTPYYLSPEICENR----PYNNK-SDIWALGCVLYEMATLRHAFEAGNMRNLIVKIVRGS------------YPPLS-------SQ
 ... ||       |||.| .|.| ...    ||... .||| |||..||| . .  |.|   . .. .|..                ||         |
QQMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQ

YSRNLRSLVDSCLKNAPRDRPSINSILRLPFI
 | ....|   .|.  ..|| |.  ..  |..
ISPECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase AqueK176.AA Pkinase_Tyr 4-199 23 4e-26 89.09 Pfam 1-210 (270) Show / Hide 
Range on Protein: 4-199
Range on HMM: 1-210/270
Sequence Identity: 23% (50 aa)

YTRIRKIGEGSYG---RALLV-KGRQDGRQYVIKVINLSKMDRRG--REEARREVKVLSQM-KHPNIVSYKDSFE-ETGS--LYIVMDYCDGGDLYKHIN
 | ..|.|||..|   .. .  .. ... .  .|..   . . .   ||.  ||.|...|. .|||||..      . ..  .|||| |. .|||...  
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

AQ--RGRLFPEDQILNWFVQLCLALKHVHDRKILHRDIKSQNVFLTKRGVVKLGDFGIARVL----NSTVELARTCIGTPYYLSPEICENRPYNNKSDIW
..   .. ..  ..|.. .| . .. . ..... |||.   |. .|. .||| .||| || .    .  .  .  .      ..||   .. .. |||.|
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYY-YRKRGGGKLPIKWMAPECINYGKFTTKSDVW

ALGCVLYEMATL
. | ...|. |.
SFGVLMWEIFTY
Kinase AqueK176.AA TyrKc 4-262 19 9.8e-25 89.42 SMART 1-280 (280) Show / Hide 
Range on Protein: 4-262
Range on HMM: 1-280/280
Sequence Identity: 19% (59 aa)

YTRIRKIGEGSYG---RALLVKGRQDGRQYVIKVINLSKMDRRGREEARREVKVLSQM--KHPNIVSYKDSFEET-------GSLYIVMDYCDGGDLYKH
 | ..|.||| .|   .. .       .|  .|... ..     ||. .|| .....   .|||||       .        . |.||| |...||| ..
ITLGKKLGEGAFGEVYKGTWK------IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDY

INAQRGRLFPEDQILNWFVQLCLALKHVHDRKILHRDIKSQNVFLTKRGVVKLGDFGIARVLNST-------VELAR----TCI--GTPYYLSPEICENR
. . |.. .. .. |.. .| .    . |.... |||.   |. ......|| .||| .| . .                  .        ..||    .
LRKHRPK-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYG

PYNNKSDIWALGCVLYEMATLRHAFEAG------NMRNLIVKIVRGSYPPLSSQ--------YSRNLRSLVDSCLKNAPRDRPSINSILRLPFIQERI
 .. |||.|. | ...|. |.      |      . . .| .. .| ..|             .  . ..  .| .  | |||. . |       |..
KFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI------HECF