Gene AqueK184 (A.queenslandica)

AqueK184

Species: A.queenslandica
Alias: AqueK184
External Links:
Annotation:

Classification

Group: Other
Family: NKF2

Sequence

Name Sequence Type Origin Length Description Download
AqueK184.AA Protein None 719 None Fasta, JSON
AqueK184.kin_dom Protein Kinase Domain None 294 None Fasta, JSON

Protein domain

Protein domains of AqueK184.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase AqueK184.AA Pkinase 552-715 21 4.7e-22 79.05 Pfam 113-293 (293) Show / Hide 
Range on Protein: 552-715
Range on HMM: 113-293/293
Sequence Identity: 21% (42 aa)

WLKDLLTGLQYLFTHYVLHRDLKLENLMLS--GDI---LKIVDFGEAIKLEPDYKIPFDRPCSKGGNEAHLAPEILNQRTGRGRVLDYTKQPVWAAGVLA
... .| ||.|.  . ..|||||.||....  |.|   .|| ||| | ...     .   . .  |    .|||...     |.  . .|  .|..|.. 
YMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD---Y-NNS-MTTFCGTPWYMAPEVIR-----GGQYYGPKVDMWSCGCIL

YELAGYQNPFSGS-----KDQRAYDERTLPRLTDTYSKTG----------------RGQKFPPEFPNIVTSMLSFEPARRPTLSEALNK--I
||..  . ||.|.      ||..  .|.... ..  . .                 .  . ..|.  .....| . |..|||  ..|.   .
YEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTF-HNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
S_TKc AqueK184.AA S_TKc 419-719 20 2.6e-21 78.06 SMART 1-231 (231) Show / Hide 
Range on Protein: 419-719
Range on HMM: 1-231/231
Sequence Identity: 20% (65 aa)

FEVLGVISRGKLAEGRSMMVVRAQCIKPGLPYPDRVYALKMLSGVHDTTTMTNARDQHKNEYEVLSSIPPHKNIVRLFAFFYDRPKAHPKLSRENCSEGI
.|.| .| .|  ..     | ... .|      .|..|.|...            .. ..| ..|..   |.|||.|. .|.|                 
YEILRKIGKGAFGK-----VYKCRHKK-----TGRIVAIKIIK------------EHIRREIQILKK--HHPNIVKLYDVFQD----------------D

ALCIMMEQLSQ---NMEYQLKPLRQTAGP---NYSKVLGWLKDLLTGLQYLFTHYVLHRDLKLENLMLSGDILKIVDFGEAIKLEPDYKIPFDRPCSKGG
 |.. || ...   ..   .|  .   ..   .   .  ... .. .|.|.  | ..||||| ||..|.   .|| ||| | .|            .  |
HLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-HIKICDFGLARQL-----------TTFCG

NEAHLAPEILNQRTGRGRVLDYT--KQPVWAAGVLAYELAGYQNPFSGSKDQRAYDERTLPRLTDTYSKTGRGQKFPPEFPNIVTSMLSFEPARRPTLSE
    .|||.|           |.  |  .|. |.. ||..  . ||.   .|. ..                    .||. ...  .| ..|..|||  |
TPWYMAPEVL----------GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG-----------------SPEAKDFIRKCLQKDPEKRPTA-E

ALN-----KITKLV
||.     |.   .
ALQDEWDIKCHPWF
Kinase AqueK184.AA CAMK 552-713 18 7.5e-21 63.27 In-house 184-421 (425) Show / Hide 
Range on Protein: 552-713
Range on HMM: 184-421/425
Sequence Identity: 18% (46 aa)

WLKDLLTGLQYLFTHYVLHRDLKLENLMLSGD------------------ILKIVDFGEAIKLEP-------------------DYKIPFDRPCSKGGNE
. . .. ...|.  | . |||||.||..|. .                   .||.||| |.|..|                   .  .. .      |  
YFRQICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTP

AHLA-PEILNQ-------------RTGRGRVLDYTKQPVWAAGVLAYELAGYQNPFSGSKDQRAYDERTLPR----LTDTYSKTGRGQ-KFPPE------
.  | ||.||.             ... |.  |     .|..||. | .     || |..|.. ..     .    . ... |  .|.  |||.      
EYMAAPEVLNGKGHCNMQNATDEEKPYYGPKCD-----MWSCGVILYIMLCGYPPFYGDCDNEICE-D-E-WIGMNDYELFEKIMKGKYDFPPPYFSPIS

----------------------FPNIVTSMLSFEPARRPTLSEALN
                        . . .||  .| .|.|....||
CNYGPEWWDDISDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCLN
Kinase AqueK184.AA Trio 547-598 35 5.4e-16 36.85 In-house 95-151 (258) Show / Hide 
Range on Protein: 547-598
Range on HMM: 95-151/258
Sequence Identity: 35% (20 aa)

SKVLGWLKDLLTGLQYLFTHYVLHRDLKLENLMLSGDIL-----KIVDFGEAIKLEP
|.| . . ..| ...||  . .|| |.| ||.|.  ...     ||.||| | .| |
SEVKTYMWQMLEAVHYLHNCHILHLDIKPENMMMWHYNAGRPQIKICDFGDAQQLWP
Kinase AqueK184.AA Ciliate-E2 552-713 18 7.6e-16 50.86 In-house 165-361 (365) Show / Hide 
Range on Protein: 552-713
Range on HMM: 165-361/365
Sequence Identity: 18% (44 aa)

WLKDLLTGLQYLFTHY-VLHRDLKLENLMLSGDILKIVDFGEAIKLEPD----------YKIPFDR---PCSKG---------------GNEAHLAPEIL
..  .. .|.||     ..|||.|.||...    .||.||| . |. .|          ....| .     . |               |.   .|||||
YIACIILALEYLHSKNNIIHRDIKPENILF----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEIL

N--------QRTGRGRVLDYTKQPVWAAGVLAYELAGYQNPFSGSKDQRAYDERTLPRLTDTYSKTGRGQKF---PPEFP--------------------
|        ...| .   |.     |..||. ||.   . ||                           |.    . .||                    
NGKKYDNQQKQKGYDYKCDI-----WSLGVILYEMLFGKPPF--------------------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKK

------NIVTS----MLSFEPARRPT-LSEALN
      ..       ||  .|  |.|  ...||
WSQECKDLIKKFGKRMLQKDPEKRITGWEQILN
Kinase AqueK184.AA CMGC 489-598 17 9e-13 37.37 In-house 97-256 (513) Show / Hide 
Range on Protein: 489-598
Range on HMM: 97-256/513
Sequence Identity: 17% (30 aa)

HKNIVRLFAFFYDR------------PKAHPKLSRENCSEGIALCIMMEQLSQNMEYQLKPLR------QTAGPNYSK------------VLGWL-----
|.|||.|. .||..            ..           .   |.. .| . ..    .|  .      .  . .  .            .   .     
HNNIVKLYDIFYHKNSDGNEYEDKHIIS---------Q-HFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRY

-KDLLTGLQ--YLFTHY--VLHRDLKLENLMLSGD---------------------ILKIVDFGEAIKLEP
 . .|.||   |.  |   ..||||| ||.... .                     .||| ||| | ...|
MYQILRGLKLKYCHSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHP
Kinase AqueK184.AA NKF2 556-675 29 5.3e-12 39.17 In-house 191-334 (365) Show / Hide 
Range on Protein: 556-675
Range on HMM: 191-334/365
Sequence Identity: 29% (43 aa)

LLTGLQYLFTHYVLHRDLKLENLM--LSGD-----ILKIVDFGEAIKLEP-DYKIPFD-RPCSKGGNEAHLAPEILN-QRTGRGRVLDYTKQPVWAAGVL
.| .  .|  | | |||.|  |    .  |      | | ||| .  ..    ..|.     ..||| .  |||| .  . |   |.|| |   ||.| .
MLEACDHLHQHGVAHRDMKSDNILVEYDFDDGACPWLVIADFGCCLACKHHGWQLPYSSWDVDRGGNACLMAPEIFTGAHPGCNHVHDYEKADTWACGAI

AYELAGYQNPFSG------------SKDQRA--YDERTLPRLTD
|||  | .||| .              | .   | |  || . .
AYEIFGQKNPFYSSSGGMAREQGEMHLDSCNSDYQEDQLPQMPQ
Kinase AqueK184.AA CDK7 552-591 43 1.8e-11 26.36 In-house 107-147 (288) Show / Hide 
Range on Protein: 552-591
Range on HMM: 107-147/288
Sequence Identity: 43% (18 aa)

WLKDLLTGLQYLFTHYVLHRDLKLENLMLSGD-ILKIVDFG
. . .| || |.  ...||||||  || .. . .||| |||
YMMMTLQGLEYCHRNWILHRDLKPNNLLMNENGQLKIADFG
Kinase AqueK184.AA TKL 430-715 13 3e-11 36.76 In-house 1-364 (364) Show / Hide 
Range on Protein: 430-715
Range on HMM: 1-364/364
Sequence Identity: 13% (55 aa)

LAEGRSMMVVRAQCI-----KPGLPYP---DRVYALKMLSGVHDTTTMTNARDQ--------------------HKNEYEVLSSIPP-HKNIVRLFAFFY
. .|..  | ....      .     |   ... | |...  .|  .. | ...                     . |.|... .   | |||.. ..  
IGSGGFGEVYKGKWRGWGGKC-----PSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCC

DRPK-------AHPKLSRENCSEGIA---LCIMMEQLSQNM-EYQLKPLRQTAGPNYSKVLGWLKDLLTGLQYLFTHY--------VLHRDLKLENLMLS
. |.                         ||| ||  .    ...|           .. . | .|   |..|| ..         ..||||| .|... 
CPPCGCVCMHPV------------GPWGQLCIVMEYCPGGSLLHYLH---------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVD

GDI---------------LKIVDFGEAIKLEPDYKIPFD---------------RPCSKGGNEAHLAPEILNQR----------TGRGRVLDYTKQP-VW
 .                .|| ||| .  .... .                   . ....|. ...|||.|..             . . ..|...  |.
ENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDE-FCKGFEYSEKCDVY

AAGVLAYELAGYQNPFSGSKD-------------QRAYDERTLPRLTDTYS-KTGRGQ----KFPPEFPNIVTSMLSFEPARRPTLSEALNKI
. |.. .|..  . |... .                ..|..  | . .. . .  . .     .||.. .. .   . .|  ||. .| | ..
SFGIVLWEILTRCRPYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHH-K-MCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase AqueK184.AA PLK1 552-717 30 6e-11 31.96 In-house 104-253 (253) Show / Hide 
Range on Protein: 552-717
Range on HMM: 104-253/253
Sequence Identity: 30% (52 aa)

WLKDLLTGLQYLFTHYVLHRDLKLENLMLSGDI-LKIVDFGEAIKLEPDYKIPFDRPCSKGGNEAHLAPEILNQRTGRGRVLDYTKQPVWAAGVLAYELA
... .. | |||    ..|||||| || |  .. .|| ||| | |.| |     .|    .|    .|||.|| ..|     |     .|. | . | | 
YMYQIVEGCQYLHNNKIIHRDLKLGNLFLNDHLQVKIGDFGLATKCEYDG----ERKKTLCGTPNYIAPEVLN-KKGHSFEVD-----IWSIGCIMYILL

GYQNPFSGSKDQRAYDERTLPRLTDTYSKTGRGQKFPPEF-----PNIVTSMLSFEPARRPTLSEALNKITK
  | ||  .            .| .|||.  . .   |.       ... .||  .| |||| .. ||.   
FGQPPFETK------------CLKETYSRIKKNEYRIPSHISQPAAQLIRKMLDPDPTRRPTIEQVLNDEFF
Kinase AqueK184.AA ULK 547-591 27 1.1e-10 33.56 In-house 130-187 (329) Show / Hide 
Range on Protein: 547-591
Range on HMM: 130-187/329
Sequence Identity: 27% (16 aa)

SKVLGWLKDLLTGLQYLFTHYVLHRDLKLENLMLSGDI-------------LKIVDFG
....  .|..| |...|  | . |||.|..| ... ..             ||| |||
QEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFG
Kinase AqueK184.AA Aur 568-591 46 1.9e-10 23.27 In-house 122-147 (257) Show / Hide 
Range on Protein: 568-591
Range on HMM: 122-147/257
Sequence Identity: 46% (12 aa)

VLHRDLKLENLMLS--GDILKIVDFG
. |||.| ||..|.   . .|| |||
IIHRDIKPENILLDQCNGNIKICDFG
TyrKc AqueK184.AA TyrKc 424-715 20 3.1e-09 -73.39 SMART 1-280 (280) Show / Hide 
Range on Protein: 424-715
Range on HMM: 1-280/280
Sequence Identity: 20% (65 aa)

VISRGKLAEGRSMMVVRAQCIKPGLPYPDRVYALKMLSGVHDTTTMTNARDQHKNEYEVLSSI-PPHKNIVRLFAFFYDRPKAHPKLSRENCSEG-----
.    || ||    |.... .        .  | |||   .        |    .| ...... . |.|||||..                |...     
ITLGKKLGEGAFGEVYKGTWK--------IQVAVKMLKEDA--------REDFMREARIMCKLGGHHPNIVRLYGV---------------CTQQGRNFM

--IALCIMMEQLSQ-NMEYQLKPLRQTAGPNYSKVLGWLKDLLTGLQYLFTHYVLHRDLKLENLMLSGD-ILKIVDFGEAIKLEPD--------YKIPFD
    |.| ||  .  .    |.  | .   . .. | .  .   | .||  . . ||||   | ... . . || ||| . ... |        |. .  
YIEPLMIVMEYMPHGDLKDYLRKHRPK--LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKE

RPCSKG-GNEAHLAPEILNQRTGRGRVLDYTKQP-VWAAGVLAYELAGY-QNPFSG-SKDQRAYDERTLPRLTDTYSKTGRGQ-------KFPPEFPNIV
. ..|.      .||| .| ..       .| .  ||. ||. .|.  | | | .|  .     ... . .. . |                |.|  .| 
HKGGKTMLPIRWMAPECINYGK-------FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQ-MMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIM

TSMLSFEPARRPTLSEALNKI
..   ..|. ||| ||   ..
KQCWHEDPEDRPTFSEIHECF
Kinase AqueK184.AA Aur 489-501 38 0.007925 2.73 In-house 58-70 (257) Show / Hide 
Range on Protein: 489-501
Range on HMM: 58-70/257
Sequence Identity: 38% (5 aa)

HKNIVRLFAFFYD
| || ... .|.|
HPNILKMYGYFHD
Kinase AqueK184.AA Trio 694-712 36 0.033904 0.71 In-house 235-253 (258) Show / Hide 
Range on Protein: 694-712
Range on HMM: 235-253/258
Sequence Identity: 36% (7 aa)

VTSMLSFEPARRPTLSEAL
... |.  |..||..||.|
ICKVLQEDPWKRPCASECL
Kinase AqueK184.AA CMGC 685-713 23 0.037901 1.81 In-house 467-509 (513) Show / Hide 
Range on Protein: 685-713
Range on HMM: 467-509/513
Sequence Identity: 23% (10 aa)

KFP--------------PEFPNIVTSMLSFEPARRPTLSEALN
||.              |.. . .  || ..|..|.| ..||.
KFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDPDKRITAEQALQ
Kinase AqueK184.AA Pkinase 473-501 32 0.19255 6.18 Pfam 42-71 (293) Show / Hide 
Range on Protein: 473-501
Range on HMM: 42-71/293
Sequence Identity: 32% (10 aa)

RDQHKN--EYEVLSSIPPHKNIVRLFAFFYD
. .| .  | ... ..  |.|||||. .|.|
DQTHRRLSEIQIMKRL-NHPNIVRLYDWFED