Gene AqueK186 (A.queenslandica)

AqueK186

Species: A.queenslandica
Alias: AqueK186
External Links:
Annotation:

Classification

Group: Other
Family: NRBP

Sequence

Name Sequence Type Origin Length Description Download
AqueK186.AA Protein None 476 None Fasta, JSON
AqueK186.kin_dom Protein Kinase Domain None 211 None Fasta, JSON

Protein domain

Protein domains of AqueK186.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase AqueK186.AA NRBP 87-292 46 8.9e-70 238.13 In-house 53-261 (261) Show / Hide 
Range on Protein: 87-292
Range on HMM: 53-261/261
Sequence Identity: 46% (101 aa)

QHQNIVNFYDFWHDKVNSKDRLVFITEYITSGSLAQFLKKNKRVKGTNSISDKIWRRWCRQILSALSYLHKNE--IIHGNLSLASIFIQHNGLVKIGSVS
.||||| |  .| |  . | |..|||||. |||. ||||| |. .   ... | |.||| ||||||||||  .  ||||||   .||||||||.|||.| 
DHQNIVKFHKYWTDTKEEKPRVIFITEYMSSGSMKQFLKKTKKNH--KNMNEKAWKRWCTQILSALSYLHSCDPPIIHGNLTCDTIFIQHNGLIKIGCVW

PNAIHQHVKTKNREAAAGLHYAAPELA---EGPMRTSADIYAFGICALEMLNLALL---GNGETVQQGQLRSDAIQKALDQL-NPRTKQFIELCIDHDYE
|.|||.||.|. ||    .|. |||        . | .|||.||.|||||  |  .   .|||. .   .  .|||.|   | .|  ..||. |. .| .
PDAIHHHVRTC-REEMRNMHFFAPEYGILEVTDLTTAVDIYSFGMCALEMAVLEIQSGCQNGESEY---VTEEAIQRAIHSLEDPMQRDFIRKCLQKDPA

KRPQAHSLIKHLVLQ
.|| |..|. | .| 
RRPSARELLFHQILF
Kinase AqueK186.AA WNK 87-181 43 2.5e-19 58.98 In-house 56-148 (261) Show / Hide 
Range on Protein: 87-181
Range on HMM: 56-148/261
Sequence Identity: 43% (43 aa)

QHQNIVNFYDFWHDKVNSKDRLVFITEYITSGSLAQFLKKNKRVKGTNSISDKIWRRWCRQILSALSYLHKNEI---IHGNLSLASIFIQ-HNGLVKIG
|| |||.|||.|   .  |   | .||  ||| |  .||  |..|       |. |.||||||. |..||  .    ||  |    |||   .| ||||
QHPNIVRFYDYWESVLCGKKCIVLVTELMTSGTLKTYLKRFKKMK------PKVLRSWCRQILKGLHFLHTRQPHPIIHRDLKCDNIFITGTTGSVKIG
Kinase AqueK186.AA STE 87-233 21 8.1e-18 59.59 In-house 87-263 (359) Show / Hide 
Range on Protein: 87-233
Range on HMM: 87-263/359
Sequence Identity: 21% (39 aa)

Q-HQNIVNFYDFWHDK---VNSKDRLVFITEYITSGSLAQFLKKNKRVKGTNS--------ISDKIWRRWCRQILSA-LSYLHKNEIIHGNLSLASIFIQ
. |.|||..|.   ..    ...| |  . ||.  ||| ...|... ......        .. .. .. ||||| . |.|||.. |||  .  | |.. 
HMHPNIVKYYGCYFKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-

HNGLVKIG------SVSPNAIHQHVKT-----------KNREAAAGLHYAAPELAEGPMRT-------SADIYAFGICALEMLN
    ||.       .....  ..   .           ..|   .|  . |||  ..  ..       ..||. .|....||..
----VKLCDFGVCGQLTDSMANI-Q-SNNIIDCIETMQQKRNTFVGTPWMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMAT
Kinase AqueK186.AA TKL 87-289 18 2.5e-16 55.32 In-house 83-364 (364) Show / Hide 
Range on Protein: 87-289
Range on HMM: 83-364/364
Sequence Identity: 18% (54 aa)

QHQNIVNFYDFWHDKVN---------SKDRLVFITEYITSGSLAQFLKKNKRVKGTNSISDKIWR---RWCRQILSALSYLHKNE--------IIHGNLS
.|.||| |. .  .  .         ..  | ...||.  |||  .|                |    ||...| ....||| ..        ||| .| 
RHPNIVQFMGYCCCPPCGCVCMHPVGPWGQLCIVMEYCPGGSLLHYLH---------------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLK

LASIFIQHNGL--------------VKIG----SVSPNAIHQHVKT---------------KNREAAAGLHYAAPELAEGPMR-----------------
 . |..  |.               .||.    | . .   .  .|               ..      . . |||. .| |                  
SKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYS

TSADIYAFGICALEMLN--LALLGNGETVQQGQ--LRSDAIQKALDQLNPRTK--------------------QFIELCIDHDYEKRPQAHSLIKHL
...|.|.|||.  |.|   .   ....  ...|  .  .... ....| |  .                    . .. | ||| |||| .  ..|.|
EKCDVYSFGIVLWEILTRCRPYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase AqueK186.AA Ciliate-E2-Unclassified 55-180 20 3.6e-15 49.07 In-house 39-188 (352) Show / Hide 
Range on Protein: 55-180
Range on HMM: 39-188/352
Sequence Identity: 20% (32 aa)

ADEVVEDEEEEEEDDEKILEIGHNGRWQK----------INHQHQNIVNFYDFWHDKVNSKDRLVFITEYITSGSLAQFLKKN-----------KRVKGT
..  .. .. |.   .|....  .   |.          .||.| .||....      ..|. . ...||.  |.| |..||.           .. | .
KQKQIMNKD-EIMNEMKEMNNKKK-YHQRKYNKIMQQILLNHPHPFIVKMFYC----FQDKQNIYIVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQR

NSISDKIWR-----RWCRQILSALSYLHKNE-IIHGNLSLASIFIQHNG---LVKI
. ....  .     ....|||..|.|||..  ||| .. .  |... ||    .||
KIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKI
Kinase AqueK186.AA ULK 81-181 25 1.8e-14 47.04 In-house 64-184 (329) Show / Hide 
Range on Protein: 81-181
Range on HMM: 64-184/329
Sequence Identity: 25% (32 aa)

WQKINHQ------HQNIVNFYDFWHDKVNSKDR--LVFITEYITSGSLAQFLKKNKRVK----GTNSISDKIWRRWCRQILSALSYLHKNEIIHGNLSLA
..|....      |.||| .||.     ....   . .|.||   | | |..||||.        . .| .. .  ..|||... .|||. |||  . ..
MKKLKSPNRHKNHHPNIVKLYDW----FETSNHNNIYIIMEYCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQ

SIFIQHN------------GLVKIG
 | |  .            | .||.
NILIHNGQPKTDSKKVHPNGVLKIA
Kinase AqueK186.AA CAMK 82-162 19 1.8e-14 42.36 In-house 89-202 (425) Show / Hide 
Range on Protein: 82-162
Range on HMM: 89-202/425
Sequence Identity: 19% (23 aa)

QKIN--HQHQNIVNFYDFWHDKV---------NSKD-------RLVFIT---EYITSG----SLAQFLKKNKR----------VKGTNSISDKIWRRWCR
|.|.   .| ||...|... |.          . ..       ......   ||.. |     | ........          |  .  .. .  ||. |
QGIGNKLDHPNIIKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIV-ERGRFTEREARRYFR

QILSALSYLHKNEIIH
||.||. |.|.. |.|
QICSAVHYCHSHNIVH
Kinase AqueK186.AA Ciliate-E2 82-180 21 2.7e-14 45.48 In-house 71-197 (365) Show / Hide 
Range on Protein: 82-180
Range on HMM: 71-197/365
Sequence Identity: 21% (29 aa)

QKIN--------------HQHQNIVNFYDFWHDKVNSKDRLVFITEYITSGSLAQFLKKNKRVKGTN-----SISDKIWRRWCRQILS------------
..||               .| ||...|... .|  ... . ...||.  |.| ...|.||  .. .     ....|  ..  .|||.            
REINCFYKKINEKNILEQLNHPNIIKMYECFQEK--DDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIAC

---ALSYLHKNE-IIHGNLSLASIFIQHNGLVKI
   || |||..  ||| .. .  |..     .||
IILALEYLHSKNNIIHRDIKPENILF-----IKI
Kinase AqueK186.AA S_TKc 67-291 21 3.2e-14 31.72 SMART 1-231 (231) Show / Hide 
Range on Protein: 67-291
Range on HMM: 1-231/231
Sequence Identity: 21% (56 aa)

EDDEKILEIGHNGRWQKINH-------------------------QHQNIVNFYDFWHDKVNSKDRLVFITEYITS--GSLAQFLKKNKRVKGTNSISDK
 .  ...  |  |.  |  |                         .| |||..||...|     |.| ...||.    |.| ...||..| ..   ..  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIKEHIRREIQILKKHHPNIVKLYDVFQD-----DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-

IWRRWCRQILSALSYLHKNEIIHGNLSLASIFIQHNGLVKIG-----SVSPNAIHQHVKTKNREAAAGLHYAAPELAEGPMRT-SADIYAFGICALEMLN
  |....||..|| |.|.. |||  |  . |.. .   .||.      .             .     ..| |||.   .  . ..|....|..  ||| 
HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------------TTFCGTPWYMAPEVL--GYGKCKCDWWSCGCILYEMLC

-LALLGNGETVQQGQLRSDAIQKALDQLNPRTKQFIELCIDHDYEKRPQAHSLIK-------HLVL
   .                ..| .    |  |.||. | . | |||| |  . .       |  .
GYPPFP---------QMQMMFKKIG---SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK186.AA CAMKL 87-162 23 1.3e-13 39.7 In-house 70-150 (297) Show / Hide 
Range on Protein: 87-162
Range on HMM: 70-150/297
Sequence Identity: 23% (20 aa)

Q---HQNIVNFYDFWHDKVN---SKDRLVFITEYITSGS--LAQFLKKNKRVKGTNSISDKIWRRWCRQILSALSYLHKNEIIH
.   |.||. .|. . .. .   . . .. ..||. .|.  | ....|.....   ... .  ||  |||.||..|.|.. |.|
NIGKHPNIIKLYEVIETPEHDIET-KKIYLVMEYCSGGEMDLFDYIVKHGHRR--GRMPEHEARRYFRQIVSAVNYCHSHGIVH
Kinase AqueK186.AA Pkinase 87-162 30 4.2e-12 43.89 Pfam 58-131 (293) Show / Hide 
Range on Protein: 87-162
Range on HMM: 58-131/293
Sequence Identity: 30% (24 aa)

QHQNIVNFYDFWHDKVNSKDRLVFITEYITSG----SLAQFLKKNKRVKGTNSISDKIWRRWCRQILSALSYLHKNEIIH
.| ||| .||...|    ||.. ...||   |    .|. ...   . .|. . |..  .....|||..| |.|.. |||
NHPNIVRLYDWFED----KDHIYMVMEYCEGGLYVMDLFDYIST--WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIH
Kinase AqueK186.AA TyrKc 69-289 17 1.4e-08 -83.78 SMART 1-280 (280) Show / Hide 
Range on Protein: 69-289
Range on HMM: 1-280/280
Sequence Identity: 17% (49 aa)

DEKILEIG-------HNGRWQ-----KINH-------------------QHQNIVNFYDFWHDK---VNSKDRLVFITEYITSGSLAQFLKKNKRVKGTN
 ... ..|       . |.|      |  .                   .|.|||..|    ..     . . |  ..||   |.| ..|.|...     
ITLGKKLGEGAFGEVYKGTWKIQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK----

SISDKIWRRWCRQILSALSYLHKNEIIHGNLSLASIFIQHNGLVKIG------SVSPN----AIHQHVKTK---NREAAAGLHYAAPE-LAEGPMRTSAD
 .. |    .| || .  .|||.. .||  |    . . .|. |||.       .       . ..  ..|   .. .   .   ||| . .|   |  |
-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSD

IYAFGICALEMLNLALLGNGET----VQQGQLRSDAIQK-ALDQLNP-----------RTKQFIELCIDHDYEKRPQAHSLIKHL
...||.|  |.. .      .     .   ... .  |   ..|                 | .. | ..| |.||    ... .
VWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase AqueK186.AA PEK 247-291 25 2.8e-08 24.13 In-house 604-655 (655) Show / Hide 
Range on Protein: 247-291
Range on HMM: 604-655/655
Sequence Identity: 25% (13 aa)

QLRS------DAIQ-KALDQLNPRTKQFIELCIDHDYEKRPQAHSLIKHLVL
.||.      . .  | .|.  |. ..|| ....|| ..||.|  . .|. .
DLRDESIQFPGDFPPKWFDNKYPKQADFIQWMLSHDPQQRPSAQQILQHEFF
Kinase AqueK186.AA PEK 112-181 18 6.2e-07 19.36 In-house 362-474 (655) Show / Hide 
Range on Protein: 112-181
Range on HMM: 362-474/655
Sequence Identity: 18% (21 aa)

TEYITSGSLAQFLKKNK---------------------------------RVKGTN------SISDKIWRRWCRQILSALSYLHKNEIIHGNLSLASIFI
.||   ..| . .. |.                                 .  ...      ... .  .|. ||||..| |.| . .||  |  . ||.
MEYCEKKTLRDWIDNNGCPVQFNYWRRNSCKNHYNNYIMNQCCFQSTWSMNM-RQWDENNCMFWDKDQCWRIFRQILEGLNYIHSQGMIHRDLKPSNIFL

-QHNG----LVKIG
 ...     .||||
DCDGQHHQMQVKIG
Kinase AqueK186.AA Ciliate-E2 203-291 16 1e-06 19.0 In-house 251-365 (365) Show / Hide 
Range on Protein: 203-291
Range on HMM: 251-365/365
Sequence Identity: 16% (19 aa)

LHYAAPELAEGPMR----------TSADIYAFGICALEMLNLALLGNGETVQQGQLRSDAIQK------------ALDQLNPRTKQFIEL----CIDHDY
..| |||  .|             ...||...|..  |||   .    .  .|.... .  ..              ... . .|..|      ... | 
PGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF-QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDP

EKRPQ-AHSLIKHLVL
|||.. .  ...|  .
EKRITGWEQILNHPWF
Kinase AqueK186.AA STE 265-291 41 7e-06 16.83 In-house 331-359 (359) Show / Hide 
Range on Protein: 265-291
Range on HMM: 331-359/359
Sequence Identity: 41% (12 aa)

KQFIELCIDHDYEKRPQAHSLIK--HLVL
|.||..| . |..||| |. |.|  |  .
KDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase AqueK186.AA WNK 207-231 56 1e-05 14.38 In-house 173-197 (261) Show / Hide 
Range on Protein: 207-231
Range on HMM: 173-197/261
Sequence Identity: 56% (14 aa)

APELAEGPMRTSADIYAFGICALEM
|||. |    .| |.|||| | |||
APEMYEEHYDESVDVYAFGMCMLEM
Kinase AqueK186.AA Ciliate-E2-Unclassified 205-291 19 4.2e-05 13.66 In-house 232-352 (352) Show / Hide 
Range on Protein: 205-291
Range on HMM: 232-352/352
Sequence Identity: 19% (24 aa)

YAAPELAEG-PMRTS----ADIYAFGICALEMLNLALLGNGETVQQ--------------GQLRSDAIQKAL-----------DQLNPRTKQFIE----L
|.|||. .|    .|    .||...|... |||   .  ....  |               ||... .|| .           ....|  | ||.     
YTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQK

CIDHDYEKRPQAHSLIKHLVL
... . .||...  ...|  .
MLKKNPNKRITFEQILNHPWF
Kinase AqueK186.AA WNK 261-291 41 4.5e-05 12.24 In-house 231-261 (261) Show / Hide 
Range on Protein: 261-291
Range on HMM: 231-261/261
Sequence Identity: 41% (13 aa)

NPRTKQFIELCIDHDYEKRPQAHSLIKHLVL
||  |..|| || |. | || .  | .|  .
NPEVKEIIEKCIRHNKEERPSIQQLLNHDFF
Kinase AqueK186.AA Pkinase_Tyr 111-181 26 0.000131 16.23 Pfam 85-153 (270) Show / Hide 
Range on Protein: 111-181
Range on HMM: 85-153/270
Sequence Identity: 26% (19 aa)

ITEYITSGSLAQFLKKNKRVKGTNSISDKIWRRWCRQILSALSYLHKNEIIHGNLSLASIFIQHNGLVKIG
..||   |.|  .|.|..   . .... |    .|.|| ....||. . .||  |    . . .|. |||.
VMEYMPHGDLLDYLRKHR--EDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKIC
Kinase AqueK186.AA Pkinase 203-289 18 0.165766 6.41 Pfam 175-293 (293) Show / Hide 
Range on Protein: 203-289
Range on HMM: 175-293/293
Sequence Identity: 18% (22 aa)

LHYAAPELAE-GPMRTS-ADIYAFGICALEMLNLALLGNGE----TVQQGQLRSDAIQKALDQLN-------------------------PRTKQFIELC
..|.|||.   |.. .. .|....|.   |||.  ..  |.    .    . . . | ..    .                         .  |.||. |
PWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWC

IDHDYEKRPQAHSLIKH--L
.. | .||| |. . .|  .
LCKDPKKRPTAEQILQHPWF