Gene AqueK189 (A.queenslandica)

AqueK189

Species: A.queenslandica
Alias: AqueK189
External Links:
Annotation:

Classification

Group: Other
Family: Other-Unique

Sequence

Name Sequence Type Origin Length Description Download
AqueK189.AA Protein None 343 None Fasta, JSON
AqueK189.kin_dom Protein Kinase Domain None 289 None Fasta, JSON

Protein domain

Protein domains of AqueK189.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase AqueK189.AA Ciliate-E2 124-243 17 6.4e-18 58.09 In-house 112-286 (365) Show / Hide 
Range on Protein: 124-243
Range on HMM: 112-286/365
Sequence Identity: 17% (32 aa)

VMELSLSGTLSKYLNKYRVN-------------EETRLRWYNDLA--------------MGLHYLHSNG-ILHWDLRPENIFIQDDQLRLANIGFMQTAK
|||.   |.| .|... . .             .| .   .  |                .|.||||.. |.| |. ||||..    . ..  |. . ..
VMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----IKIIDFGLSKKYD

ESNRKKFNFNHSVFLEEYVEE----------------------AIPFIAPETFGGV----------YNKSSEIFSLGLIF
..| ... ....  . .   .                        .. ||| ..|           |.... |.||| |.
DDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVIL
Kinase AqueK189.AA Ciliate-E2-Unclassified 124-243 19 1e-15 51.05 In-house 99-260 (352) Show / Hide 
Range on Protein: 124-243
Range on HMM: 99-260/352
Sequence Identity: 19% (32 aa)

VMELSLSGTLSKYLNK------------------YRVNEETRL-----RWYNDLAMGLHYLHSNG-ILHWDLRPENIFIQDD----QLRLANIGFMQTAK
|||.   |.|..|..|                   .. |.  .     ..   .  || |||... |.| |. ||||.....    .....  |.    .
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQ

ESNRKKFNF---NHSVFLEEYVEEA---IPFI----APETFGG-VYN----KSSEIFSLGLIF
..| .. ..   . ... ..        . ..    ||| ..|  |.    ... |.||| |.
QNNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVIL
S_TKc AqueK189.AA S_TKc 33-319 17 2e-13 20.07 SMART 1-220 (231) Show / Hide 
Range on Protein: 33-319
Range on HMM: 1-220/231
Sequence Identity: 17% (54 aa)

YSYEKVLHEGTYGTTLLARRGKFGPRLAILLFHLPWANTVREVHLKKLSGLRHKNLVHLIDCYDCHDPPLTTMSMTQFPSKSLPPPTAVAVVMELSLS--
|   ... .|..|.  ..|  | | . ||   .    .. ||. . |    .|.|.|.|.|...                      . . .|||.     
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---EHIRREIQILKK---HHPNIVKLYDVFQD---------------------DHLYMVMEYCDGDL

GTLSKYLNKYR-------VNEETRLRWYNDLAMGLHYLHSNGILHWDLRPENIFIQDDQLRLANIGFMQTAKESNRKKFNFNHSVFLEEYVEEAIPFIAP
|.| .|. |..        .| .  ..   .. .| |.||.||.| || ||||.. . .. ..  |.                       .     ..||
GDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-HIKICDFGLARQL-----------------TTFCGTPWYMAP

ETFGGVYNK-SSEIFSLGLIFLAIAE------SPDCGYHKARWSNTTDVLGKLLHSRLPPRTTKPVHLLEPPVTQARPQESSLFNEMLSHNPHSRPTTEG
| .   |.| .. . |.| |.   .        ..  ..| .                                   |.  .. . .|  .|  |||   
EVL--GYGKCKCDWWSCGCILYEMLCGYPPFPQMQMMFKKIG----------------------------------SPEAKDFIRKCLQKDPEKRPTA-E

VLT
.|.
ALQ
Kinase AqueK189.AA TKL-Unique 116-242 19 4.7e-13 42.55 In-house 70-217 (290) Show / Hide 
Range on Protein: 116-242
Range on HMM: 70-217/290
Sequence Identity: 19% (30 aa)

PPPTAVAVVMELSLSGTLSKYLN-----------KYRVNEETRLRWYNDLAMGLHYLHSNG--ILHWDLRPENIFIQDD------QLRLANIGFMQTAKE
..|     |||    |.| ..|.           ..  | . |..  .| | |..|||...  |.| ||.. |. .  .      . ...  |.  ... 
VYPPNMCIVMEYCPGGSLYDVLHQNNNNNNNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSK

SNRKKFN----FNHSVFLEEYVEEAIPFIAPETFGG---VYNKSSEIFSLGLI
.|....|     .     .. ..  .  .||| . .    |...|...| | .
INKMTNNEHKGTR-----NQTRCGSFRWMAPEVLRMNFCQYSEKSDVYSFGIV
Kinase AqueK189.AA Trio 157-181 44 8.7e-13 28.46 In-house 107-131 (258) Show / Hide 
Range on Protein: 157-181
Range on HMM: 107-131/258
Sequence Identity: 44% (11 aa)

GLHYLHSNGILHWDLRPENIFIQDD
..||||...||| |..|||. . ..
AVHYLHNCHILHLDIKPENMMMWHY
Kinase AqueK189.AA TKL 68-321 17 4.9e-12 39.63 In-house 67-364 (364) Show / Hide 
Range on Protein: 68-321
Range on HMM: 67-364/364
Sequence Identity: 17% (57 aa)

WANTVREVHLKKLSGLRHKNLVHLID-CY------DCHDPPLTTMSMTQFPSKSLPPPTAVAVVMELSLSGTLSKYLNKYRVNEETRLRWYNDLAMGLHY
|..  .|. .. .| ||| |.|...  |        |..|                |..  . |||.   |.|  ||.      . |.||  | | |..|
WFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCGCVCMHPV--------------GPWGQLCIVMEYCPGGSLLHYLH-----WHQRCRWALDIARGMNY

LHSNG--------ILHWDLRPENIFIQDD-Q--------------LRLANIGFMQTAKESNRKKFNFNHSV---------FLEEYVEEAIPFIAPETF--
|||..        |.| || ..||.. .. .              . ..  |. .. ..|. .. . ..                .   . . ||| .  
LHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRG

---------------GGVYNKSSEIFSLGLIFLAIAE--SPDCGYHKARWSNTTDV-------LGKLLHSRLPPRTTKPV-HLLEPPVTQARPQE----S
               |. |.... ..| |...  |.        |..   .             .  .... ||. . .  |.  . . .  |.     .
QMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCR---PYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHH--K-M-CPCPDCPPSMK

SLFNEMLSHNPHSRPTTEGVLTSL
.|  .  .|.|..||. . .|  |
KLMQDCWDHDPEKRPSFQEILKRL
Kinase AqueK189.AA Ciliate-C8 157-243 21 3.3e-11 36.74 In-house 131-238 (238) Show / Hide 
Range on Protein: 157-243
Range on HMM: 131-238/238
Sequence Identity: 21% (23 aa)

GLHYLHSNGILHWDLRPENIFIQDD-----QLRLAN----IGFMQTAKESNRKK-FNFNHSVFLEEYVEEA----IPFIAPETFGGVYNKSSEIFS----
.. ||| . |.| |  |.|.  ..|     .  |..      | . .. .. |  . .   .  ..|.|..    . ..|||   ... . | |||    
SVNYLHCFNIMHRDIKPHNFLVCFDQQYQPTIKLCDFKKQCDFGFASQLPKNKSHYHSKKFKGTDQYIEMYFCGNWGYFAPEVEKKQSRIQSDIFSKKSD

---LGLIF
   .||..
SYSVGLVL
Kinase AqueK189.AA MLCK 157-180 50 5.7e-11 24.62 In-house 109-132 (257) Show / Hide 
Range on Protein: 157-180
Range on HMM: 109-132/257
Sequence Identity: 50% (12 aa)

GLHYLHSNGILHWDLRPENIFIQD
|.|..|...|.| ||.|||| .|.
GVHHMHWQNIVHLDLKPENIMCQT
Kinase AqueK189.AA CAMK 38-190 15 5.2e-10 27.71 In-house 1-242 (425) Show / Hide 
Range on Protein: 38-190
Range on HMM: 1-242/425
Sequence Identity: 15% (42 aa)

VLHEGTYGTTLLARRGKFG------------PRLAILLFHL--------------------------------PWANTVREVH-LKKLSG----LRHKNL
.| .|..|.  |... . .             . ||                                       .|  ||.. .|||.|    |.|.|.
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VHLIDCYD-------CHDPPLTTMSMTQFPSKSLPPPTA-------------VAVVM---ELSLSG----TLSKYLNK----------------YRVNEE
..|.. |.                             .              .  ||   |.   |     |  |. .                 |..|.
IKLYEVYEDPHYFKNT---------------------NDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTER

TRLRWYNDLAMGLHYLHSNGILHWDLRPENIFIQDD------------------QLRLANIGF
   |.   .. ..||.||..| | || |||| ..|.                  .. ..  ||
EARRYFRQICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGF
Kinase AqueK189.AA WEE 153-178 59 7.4e-10 29.32 In-house 119-145 (297) Show / Hide 
Range on Protein: 153-178
Range on HMM: 119-145/297
Sequence Identity: 59% (16 aa)

DLAMGLHYLHSN-GILHWDLRPENIFI
|.. |||..||| |..| |. ||||||
DICQGLHHIHSNCGMVHMDIKPENIFI
Kinase AqueK189.AA Pkinase 80-186 23 1.7e-09 34.69 Pfam 54-154 (293) Show / Hide 
Range on Protein: 80-186
Range on HMM: 54-154/293
Sequence Identity: 23% (29 aa)

LSGLRHKNLVHLIDCY-DCHDPPLTTMSMTQFPSKSLPPPTAVAVVMELSLSG----TLSKYLN---KYRV--NEETRLRWYNDLAMGLHYLHSNGILHW
.  |.|.| | |.|.. |                     .. . .|||.   |     |. |.    . ..   |..  ..   .. || |.||.||.| 
MKRLNHPNIVRLYDWFED---------------------KDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHR

DLRPENIFIQ-DDQL----RLA
|| ||||.|  ....    ...
DLKPENILIDNNGHIDACVKIC
Kinase AqueK189.AA PEK 124-187 17 2.4e-09 27.9 In-house 361-475 (655) Show / Hide 
Range on Protein: 124-187
Range on HMM: 361-475/655
Sequence Identity: 17% (20 aa)

VMELSLSGTLSKYLNKY---------------------------------------------RVNEETRLRWYNDLAMGLHYLHSNGILHWDLRPENIFI
.||.   .||. ...                                                ..... .|.  ... || |.||.|. | ||.| |||.
QMEYCEKKTLRDWIDNNGCPVQFNYWRRNSCKNHYNNYIMNQCCFQSTWSMNMRQWDENNCMFWDKDQCWRIFRQILEGLNYIHSQGMIHRDLKPSNIFL

-QDDQ-----LRLAN
 .|.|     .. ..
DCDGQHHQMQVKIGD
TyrKc AqueK189.AA TyrKc 33-321 16 7e-06 -127.72 SMART 1-280 (280) Show / Hide 
Range on Protein: 33-321
Range on HMM: 1-280/280
Sequence Identity: 16% (57 aa)

YSYEKVLHEGTYGTTLLARRGKFGPRLAILLFHLPWANTVREVHLKKLS---------------GL--RHKNLVHLIDCYDCHD--------PPLTTMSM
 . .|.| || .|.  ...                     ..|  |.|                 |  .|.|.| |.    | .        .||     
ITLGKKLGEGAFGEVYKGTWK-------------------IQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLY--GVCTQQGRNFMYIEPLM----

TQFPSKSLPPPTAVAVVMELSLSGTLSKYLNKYR--VNEETRLRWYNDLAMGLHYLHSNGILHWDLRPENIFIQDDQ-LRLANIGFMQTAKES-NRKKFN
               .|||.   | | .|| |.|  .. .. | .  . | |  ||||... | ||   |. . ...  . .  | .   ..  ..    
---------------IVMEYMPHGDLKDYLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQG---

FNHSVFLEEY--VEEA-IPF--IAPETF-GGVYNKSS----------EIFSLGLIFLAIAESPDCGYHKARWSNTTDVLGKLLHSRLPPRTTKPVHLLEP
 ....        . . .|    |||..  |...  |          |||..|       ..|  |  .    . ..|. .. . . .|.   .      
ESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYG-------QQPYPGMIQQ-MMSNQEVIEYVKQGYRMPQPPNDY-----

PVTQARP-----QESSLFNEMLS---HNPHSRPTTEGVLTSL
      |       . ... |..   ..|..||| . .   .
------PMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase AqueK189.AA PEK 294-323 30 0.010887 4.32 In-house 626-655 (655) Show / Hide 
Range on Protein: 294-323
Range on HMM: 626-655/655
Sequence Identity: 30% (9 aa)

PQESSLFNEMLSHNPHSRPTTEGVLTSLEG
|..... . ||||.|  ||...  | ..  
PKQADFIQWMLSHDPQQRPSAQQILQHEFF
Kinase AqueK189.AA WEE 219-247 33 0.015703 4.39 In-house 198-230 (297) Show / Hide 
Range on Protein: 219-247
Range on HMM: 198-230/297
Sequence Identity: 33% (11 aa)

PFIAPETFGG--VYNKS--SEIFSLGLIFLAIA
...|||.  |   | ..  . |||||. .. .|
RYMAPEILQGYYHYTHLYKADIFSLGITIYELA
Kinase AqueK189.AA TKL-Unique 306-321 31 0.114981 1.87 In-house 275-290 (290) Show / Hide 
Range on Protein: 306-321
Range on HMM: 275-290/290
Sequence Identity: 31% (5 aa)

HNPHSRPTTEGVLTSL
|.|  ||. . ....|
HDPSQRPSFDEIIHRL