Gene AqueK191 (A.queenslandica)

AqueK191

Species: A.queenslandica
Alias: AqueK191
External Links:
Annotation:

Classification

Group: Other
Family: Other-Unique

Sequence

Name Sequence Type Origin Length Description Download
AqueK191.AA Protein None 1019 None Fasta, JSON
AqueK191.kin_dom Protein Kinase Domain None 240 None Fasta, JSON

Protein domain

Protein domains of AqueK191.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc AqueK191.AA S_TKc 666-1018 15 1.6e-13 21.2 SMART 1-231 (231) Show / Hide 
Range on Protein: 666-1018
Range on HMM: 1-231/231
Sequence Identity: 15% (58 aa)

LPRTRVLREGGNGIILEVNFEG--TTYAVKQT-AFRWREVLIMPKLHHPNVLQCLALLMGQPLVSFPRRRNIFHFYPRMTN---DLGRNVGSYERYCLRS
    |.. .|. |    .   .    .|.|.     .||. |. | ||||. ...               ... .   . .   ||        .  ...
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIKEHIRREIQILKK-HHPNIVKLYDVFQD---------DHLYMVMEYCDGDLGDL--------FDYIKK

LRERYKNEMLLLNKIDNNFKLLFRSVLEALNYLHTLPNPIVHRDIKPSNILLKTLCACPNILTCVCRNTPQIVLSDFDASLELNTDGTLLPDPPRTTSKD
 . . ..  .    .    . ... ...||.|.| .   |.|||.||.|||| .                .| ..||  . .|                 
RGRHGLRFPFPE-HA----RFYMYQICCALEYCHSH--GIIHRDLKPENILLDE----------------HIKICDFGLARQL-----------------

FYVTTDRTYHMSPVGTIGFKAPEVFMYTISNSTDLMEQMPI-KADIFSFG--LFSLLV---LLNEEGPKYLNQVGTLLLSVHQSSNMFKPLDQAKRAMLL
          .. .||  . ||||.            .    |.|. |.|  |. .|.   .   .  . ....|                         
----------TTFCGTPWYMAPEVL------------GYGKCKCDWWSCGCILYEMLCGYPPFP-QMQMMFKKIG-------------------------

KNGITEFRVSEPCVQAADINRILPFGRLKKSLSEVPHLIDFVEKCLVLVPANRVIAKDLLN-------HPYL
                                   | ..||..|||.  |..|  | ..|.       ||..
----------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK191.AA Ciliate-E2 779-908 21 6.7e-13 40.6 In-house 148-283 (365) Show / Hide 
Range on Protein: 779-908
Range on HMM: 148-283/365
Sequence Identity: 21% (36 aa)

KLLFRSVLE---------------ALNYLHTLPNPIVHRDIKPSNILLKTLCACPNILTCVCRNTPQIVLSDFDASLELNTD---------GTLLPDPP-
| ... .|.               ||.|||   | |.||||||.|||.                   | ..||  | ....|           ....   
KYIMKQILQGFKTKAEFYIACIILALEYLHSKNN-IIHRDIKPENILF-------------------IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KN

---RTTSKDFYVTTDRTYHMSPV-----------GTIGFKAPEVFMYTISNSTDLMEQMPIKADIFSFG
   ||... .                        || |..|||....   .   . ..   |.||.|.|
DTSRTPGYMD------------QIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLG
Kinase AqueK191.AA STE 783-909 24 8.1e-13 41.71 In-house 158-256 (359) Show / Hide 
Range on Protein: 783-909
Range on HMM: 158-256/359
Sequence Identity: 24% (34 aa)

RSVLEA-LNYLHTLPNPIVHRDIKPSNILLKTLCACPNILTCVCRNTPQIVLSDFDASLELNTDGT----------LLPDPPRTTSKDFYVTTDRTYHMS
|..|.. |.||| .   |.||||||.||||                   . |.||  .  |. ...                          |      .
RQILKGLLYYLHSHH--IIHRDIKPANILL-------------------VKLCDFGVCGQLTDSMANIQSNNIIDCI--------------ETMQQKRNT

PVGTIGFKAPEVFMYTISNSTDLMEQMPIKADIFSFGL
 |||  . |||| .   .. .  . .  .|.|| |.|.
FVGTP-WMAPEVIQQNGQG-R--DKGYDTKCDIWSLGC
Kinase AqueK191.AA Pkinase 779-909 19 1.1e-12 45.96 Pfam 111-200 (293) Show / Hide 
Range on Protein: 779-909
Range on HMM: 111-200/293
Sequence Identity: 19% (27 aa)

KLLFRSVLEALNYLHTLPNPIVHRDIKPSNILLK---TLCACPNILTCVCRNTPQIVLSDFDASLELNTDGTLLPDPPRTTSKDFYVTTDRTYHMSPVGT
|  .. .|..|.|.|     |.|||.||.|||..   ...|              . ..||  .  ..                   .   .  ....||
KFYMYQILRGLEYCHSM--GIIHRDLKPENILIDNNGHIDA-------------CVKICDFGLAKQFD-------------------Y-NNS-MTTFCGT

IGFKAPEVFMYTISNSTDLM--EQMPIKADIFSFGL
... ||||          ..  .  . |.|..|.|.
PWYMAPEV----------IRGGQYYGPKVDMWSCGC
Kinase AqueK191.AA STE-Unique 785-811 59 2.2e-10 32.54 In-house 412-438 (616) Show / Hide 
Range on Protein: 785-811
Range on HMM: 412-438/616
Sequence Identity: 59% (16 aa)

VLEALNYLHTLPNPIVHRDIKPSNILL
.||.|.|||.  |||.|||.||.||..
ILEGLEYLHSQHNPIIHRDLKPHNIFC
Kinase AqueK191.AA GSK 786-811 53 4.3e-10 26.41 In-house 126-149 (328) Show / Hide 
Range on Protein: 786-811
Range on HMM: 126-149/328
Sequence Identity: 53% (14 aa)

LEALNYLHTLPNPIVHRDIKPSNILL
. .|.||| .   |.||||||.|||.
FRGLAYLHSHG--ICHRDIKPQNILV
Kinase AqueK191.AA CMGC 983-1018 36 1.2e-09 26.93 In-house 478-513 (513) Show / Hide 
Range on Protein: 983-1018
Range on HMM: 478-513/513
Sequence Identity: 36% (13 aa)

KSLSEVPHLIDFVEKCLVLVPANRVIAKDLLNHPYL
| . . | .||...|.|.. |..|  |.. |.|||.
KRKCCDPQAIDLLKKMLQYDPDKRITAEQALQHPYF
Kinase AqueK191.AA CAMK-Unique 780-813 35 2e-09 27.07 In-house 161-192 (363) Show / Hide 
Range on Protein: 780-813
Range on HMM: 161-192/363
Sequence Identity: 35% (12 aa)

LLFRSVLEALNYLHTLPNPIVHRDIKPSNILLKT
......|.|..|.|   . |||||.|. ||....
FIMQCLLSAVAYMHS--QDIVHRDLKLENIMVCY
Kinase AqueK191.AA CMGC 776-811 34 5.1e-09 24.81 In-house 174-217 (513) Show / Hide 
Range on Protein: 776-811
Range on HMM: 174-217/513
Sequence Identity: 34% (15 aa)

NNFKLLF------RSVLEALN--YLHTLPNPIVHRDIKPSNILL
.| | ..      . .|..|.  |.|   . |.|||.||.|||.
HNIKYFMIHIRYMYQILRGLKLKYCHSHWGNIIHRDLKPENILI
Kinase AqueK191.AA MST 991-1018 46 5.8e-09 24.54 In-house 227-254 (254) Show / Hide 
Range on Protein: 991-1018
Range on HMM: 227-254/254
Sequence Identity: 46% (13 aa)

LIDFVEKCLVLVPANRVIAKDLLNHPYL
..||| |||.. |  |  |..||.||  
FNDFVCKCLQKNPEQRWTAEQLLQHPFI
Kinase AqueK191.AA STE20 989-1018 46 1.5e-08 27.68 In-house 259-288 (288) Show / Hide 
Range on Protein: 989-1018
Range on HMM: 259-288/288
Sequence Identity: 46% (14 aa)

PHLIDFVEKCLVLVPANRVIAKDLLNHPYL
|.. |||.|||.  |..|  |..||.||..
PEFHDFVDKCLQKDPEKRPTASQLLKHPFI
Kinase AqueK191.AA YSK 991-1018 42 4.2e-08 20.11 In-house 230-257 (257) Show / Hide 
Range on Protein: 991-1018
Range on HMM: 230-257/257
Sequence Identity: 42% (12 aa)

LIDFVEKCLVLVPANRVIAKDLLNHPYL
...||| ||.  |..|  ||.|| |   
FKEFVECCLNKDPEQRPSAKELLKHKFI
Kinase AqueK191.AA STE 980-1018 27 8.9e-08 23.67 In-house 302-359 (359) Show / Hide 
Range on Protein: 980-1018
Range on HMM: 302-359/359
Sequence Identity: 27% (16 aa)

RLKKSLSEV-----------------PHLIDFVEKCLVLVPANRVIAKDLLN--HPYL
.|.  ||..                 |...||..|||.  | .|  |..||.  || .
PLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase AqueK191.AA CDK 779-811 45 2.2e-07 19.53 In-house 111-141 (284) Show / Hide 
Range on Protein: 779-811
Range on HMM: 111-141/284
Sequence Identity: 45% (15 aa)

KLLFRSVLEALNYLHTLPNPIVHRDIKPSNILL
| ...  |..|.|.|   | |.|||.||.|||.
KCYMWQLLRGLHYCHS--NWIMHRDLKPQNILI
Kinase AqueK191.AA CDK 993-1018 38 2.4e-07 19.41 In-house 259-284 (284) Show / Hide 
Range on Protein: 993-1018
Range on HMM: 259-284/284
Sequence Identity: 38% (10 aa)

DFVEKCLVLVPANRVIAKDLLNHPYL
|. .|.|.. |..|. |.. |.|||.
DLLNKMLCYDPKKRISAEQALQHPYF
Kinase AqueK191.AA MST 783-811 51 1e-06 16.97 In-house 104-130 (254) Show / Hide 
Range on Protein: 783-811
Range on HMM: 104-130/254
Sequence Identity: 51% (15 aa)

RSVLEALNYLHTLPNPIVHRDIKPSNILL
...|  | |||   | ..|||||. ||||
YDTLQGLQYLHD--NKKIHRDIKAGNILL
Kinase AqueK191.AA STE20 783-811 62 2e-06 20.24 In-house 124-150 (288) Show / Hide 
Range on Protein: 783-811
Range on HMM: 124-150/288
Sequence Identity: 62% (18 aa)

RSVLEALNYLHTLPNPIVHRDIKPSNILL
| ||..|.|||   | |.|||||  ||||
REVLQGLDYLHS--NHIIHRDIKADNILL
Kinase AqueK191.AA YSK 783-811 48 3e-06 14.65 In-house 106-132 (257) Show / Hide 
Range on Protein: 783-811
Range on HMM: 106-132/257
Sequence Identity: 48% (14 aa)

RSVLEALNYLHTLPNPIVHRDIKPSNILL
| .| .| |||   .  .|||||  |.||
REILKGLDYLHS--ERKIHRDIKAANVLL
Kinase AqueK191.AA GSK 981-1018 28 3e-06 14.54 In-house 290-328 (328) Show / Hide 
Range on Protein: 981-1018
Range on HMM: 290-328/328
Sequence Identity: 28% (11 aa)

LKKSLSEVPH-LIDFVEKCLVLVPANRVIAKDLLNHPYL
. |.. . .  .||.. ||||  | .|  . ... ||. 
MFKWCHTDMQDWIDLISKCLVYDPKKRLSPLEACAHPFF
Kinase AqueK191.AA CAMK-Unique 991-1018 39 4.2e-05 12.56 In-house 336-363 (363) Show / Hide 
Range on Protein: 991-1018
Range on HMM: 336-363/363
Sequence Identity: 39% (11 aa)

LIDFVEKCLVLVPANRVIAKDLLNHPYL
..|||..|... |. |. || || |...
AKDFVKCCMTVDPDHRWSAKELLEHQWI
Kinase AqueK191.AA Pkinase 991-1018 35 4.4e-05 19.07 Pfam 266-293 (293) Show / Hide 
Range on Protein: 991-1018
Range on HMM: 266-293/293
Sequence Identity: 35% (10 aa)

LIDFVEKCLVLVPANRVIAKDLLNHPYL
..||...|| . |. |  |...|.||..
CKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase AqueK191.AA Ciliate-E2 992-1018 28 9.8e-05 12.16 In-house 334-365 (365) Show / Hide 
Range on Protein: 992-1018
Range on HMM: 334-365/365
Sequence Identity: 28% (9 aa)

IDFVEK----CLVLVPANRVI-AKDLLNHPYL
.|.  |    .|.  | .|   ....||||..
KDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase AqueK191.AA STE-Unique 989-1018 43 0.00059 9.28 In-house 587-616 (616) Show / Hide 
Range on Protein: 989-1018
Range on HMM: 587-616/616
Sequence Identity: 43% (13 aa)

PHLIDFVEKCLVLVPANRVIAKDLLNHPYL
| ...| |||| . |  |. |..|| |. |
PEQQQFIEKCLERNPHHRPSAHQLLHHFWL
Kinase AqueK191.AA GSK 700-717 38 0.014032 3.03 In-house 50-70 (328) Show / Hide 
Range on Protein: 700-717
Range on HMM: 50-70/328
Sequence Identity: 38% (8 aa)

REVLIMPKL---HHPNVLQCL
||. || .|   .|||. ...
RELQIMKMLGKLDHPNIVRLK
Pkinase AqueK191.AA Pkinase 692-717 38 1.223863 3.34 Pfam 41-66 (293) Show / Hide 
Range on Protein: 692-717
Range on HMM: 41-66/293
Sequence Identity: 38% (10 aa)

VKQTAFRWREVLIMPKLHHPNVLQCL
..||..| .|. || .|.|||.....
KDQTHRRLSEIQIMKRLNHPNIVRLY