Gene AqueK197 (A.queenslandica)

AqueK197

Species: A.queenslandica
Alias: AqueK197
External Links:
Annotation:

Classification

Group: Other
Family: PEK
Subfamily: PEK

Sequence

Name Sequence Type Origin Length Description Download
AqueK197.AA Protein None 1193 None Fasta, JSON
AqueK197.kin_dom Protein Kinase Domain None 155 None Fasta, JSON

Protein domain

Protein domains of AqueK197.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase AqueK197.AA PEK 1022-1175 28 2.8e-51 176.58 In-house 436-655 (655) Show / Hide 
Range on Protein: 1022-1175
Range on HMM: 436-655/655
Sequence Identity: 28% (63 aa)

ILDAVIYMHDKDYIHCDLKPSNILFAMNDS-----IKVGDFGLVKQNA--------------------ATKHSAPQTDVQGS------------------
||... |.| .  || |||||||.. ...      .|.|||||.....                    |.. .  ..  | .                  
ILEGLNYIHSQGMIHRDLKPSNIFLDCDGQHHQMQVKIGDFGLATNHEMLSQSQKNYNQQDQSYWKYVANDNCQWWNTNQQNSPTGQDTHMWSNNYHIQP

----------HTSEIGTLFYVSPEQEAGH-----QYNERADVYSLGIILFELYFPFSTRM-ERVKVLEDIKS-NRRLPKEFK-ENLHN----EAKLVELM
          ||. .||..|.||||. |      .||...|.||||||.||...||.| | ||||.| |... .  .| .|  ... |    .|... .|
TSMFYCEHCHHTGGVGTCLYMSPEQLSGQHYQKSHYNHKVDMYSLGIIFFEMWYPFFTTMMERVKTLTDLRDESIQFPGDFPPKWFDNKYPKQADFIQWM

LKPISD-RPSSSEIKEIDAF
|..  . |||...| . . |
LSHDPQQRPSAQQILQHEFF
Kinase AqueK197.AA GCN2 1022-1169 29 1.3e-42 146.85 In-house 317-505 (511) Show / Hide 
Range on Protein: 1022-1169
Range on HMM: 317-505/511
Sequence Identity: 29% (57 aa)

ILDAVIYMHDKDYIHCDLKPSNILFAMNDSIKVGDFGLVK------------------------------QNAATKHSAPQTDVQG------SHTSEIGT
||... |.|..  || |||||||..  .. .|.|||||..                              |....   . |.. ..      .||. .||
ILEGLNYIHSQGMIHRDLKPSNIFLDCCGNVKIGDFGLATNNKMESQINRKQQKQQQQASSHWAIQNEICQDDQFNQQQSQFSQWDQQDEQVHHTGKVGT

LFYVSPEQEAGHQYNERADVYSL-GIILFELYFP-FSTRMERVKVLEDIKSNRRLPKEFK---ENLHN-EAKLVELMLKPISD-RPSSSEI
 ||..|||.    ||...|.||| |||.||. .| |.| ||||..| ... .  .|. |    .| |  ...... .|.. .. ||| ...
PFYMCPEQQ-KSHYNQKVDMYSLGGIIFFEMWYPPFCTQMERVQILKQLR-SCEFPQDFDKKVDNHHKDQQDMIRWCLNHDPQKRPSAQQL
Kinase AqueK197.AA PEK 1079-1175 33 7.7e-33 106.11 In-house 645-758 (758) Show / Hide 
Range on Protein: 1079-1175
Range on HMM: 645-758/758
Sequence Identity: 33% (39 aa)

HTSEIGTLFYVSPEQEAGH----------------QYNERADVYSLGIILFELYFP-FSTRMERVKVLEDIKSNRRLPKEFKENLHNEAKLVELMLKPI-
||   ||. | ||||  .                 .||.  | ||||.|.|||..| |||.|||.... |.. |  .|| |  ..  |.... .|...  
HTVQVGTHLYMSPEQCHHQSVFGTGTYTNPEQKKTWYNHKVDIYSLGLIFFELIHPGFSTQMERIRTMCDLR-NGQWPKWFTQKYPQEYEFIQQMMSMNP

SDRPSSSEIKEIDAF
. ||....|.. | |
DERPTADQISMHDFF
Kinase AqueK197.AA HRI 1022-1175 31 1.3e-26 90.49 In-house 442-613 (613) Show / Hide 
Range on Protein: 1022-1175
Range on HMM: 442-613/613
Sequence Identity: 31% (55 aa)

ILDAVIYMHDKDYIHCDLKPSNILFAMNDS----IKVGDFGLVKQNAATK--------------HSAPQTDVQGSHTSEIGTLFYVSPEQEAGHQYNERA
|.  . | | .  .| |.|| ||     |     .|.|||||  .   ..               .     |   ||| .||  | ||||  | ||  . 
IVEGMFYIHNMFIVHRDVKPRNIFLHDPDQGHPQVKIGDFGLACEDILQEPKTPMRFRRDQDFDWTNRNPCVTQTHTSRVGTCTYASPEQLDGSQYDNKS

DVYSLGIILFELYFPFSTRMERVKVLEDIKSNRRLPKEFKENLHNEAKLVELML-KPISDRPSSSEIKEIDAF
| ||.|.|||||. || | ||| .||  ..   ..|   .      || . ..  .  | |||   .   . |
DMYSMGVILFELFQPFGTEMERAEVLTGVRTG-QIPESLRKRCPVQAKYIQHLTRRNASQRPSAIQLLQSELF
Kinase AqueK197.AA Pkinase 1022-1117 35 3.1e-23 83.24 Pfam 117-207 (293) Show / Hide 
Range on Protein: 1022-1117
Range on HMM: 117-207/293
Sequence Identity: 35% (36 aa)

ILDAVIYMHDKDYIHCDLKPSNILFAMNDSI----KVGDFGLVKQNAATKHSAPQTDVQGSHTSEIGTLFYVSPEQEA-GHQYNERADVYSLGIILFELY
|| .. |.|..  ||.||||.|||.  |. |    |..|||| ||          .  ..  |.  ||..|..||    |  |  ..|..|.|.||.|..
ILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD--------Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEML

F
.
C
Kinase AqueK197.AA Ciliate-E2 1022-1175 20 4e-22 72.74 In-house 169-365 (365) Show / Hide 
Range on Protein: 1022-1175
Range on HMM: 169-365/365
Sequence Identity: 20% (44 aa)

ILDAVIYMHDKD-YIHCDLKPSNILFAMNDSIKVGDFGLVKQNA---------ATKHSAPQTDVQGSHTSE--------------IGTLFYVSPEQEA--
|..|. |.| |   || |.||.||||     ||. |||| |..                ..  .. | |.               .||. |..||     
IILALEYLHSKNNIIHRDIKPENILF-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGK

-------GHQYNERADVYSLGIILFEL---YFPFSTRMERVKVLEDIKSNRRLPKEFK----------------ENLHNEAKLVELMLK--------PIS
       ...|.. .|..|||.||.|.   ..||            .. .   . .|                 .... . .   |. |          .
KYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPE

DRPS-SSEIKEIDAF
 |..  ..|..   |
KRITGWEQILNHPWF
Kinase AqueK197.AA Ciliate-E2-Unclassified 1022-1175 25 2e-21 71.06 In-house 152-352 (352) Show / Hide 
Range on Protein: 1022-1175
Range on HMM: 152-352/352
Sequence Identity: 25% (52 aa)

ILDAVIYMHDKD-YIHCDLKPSNILFAMND---SIKVGDFGLVKQNAA---------TKHSAPQTDVQGSHTSEIGTLFYV----SPEQEAGHQYNER--
||..  |.| |   || |.||.||||  |     ||. |||. |..           .| . .. . .   .. .||. |     .||   |..|...  
ILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMM---WTFCGTPNYMPQYTAPEVLQGQNYDHSKA

--ADVYSLGIILFEL---YFPFS--TRME-------------RVKVLEDIKSNRRLPKEFKE-----NLHNEAK-LVE----LMLKPISD-RPSSSEIKE
  .|..|||.||.|.   |.||.  .. .             |  ....|| .    ..|..     ....||| ...     |||   . |.. ..|..
YKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILN

IDAF
   |
HPWF
Kinase AqueK197.AA TKL 1022-1173 18 1.8e-20 70.44 In-house 141-364 (364) Show / Hide 
Range on Protein: 1022-1173
Range on HMM: 141-364/364
Sequence Identity: 18% (41 aa)

ILDAVIYMHDKD--------YIHCDLKPSNILFAMNDS--------------IKVGDFGLVKQNAATKHSAPQTDVQG----------SHTSEIGTLFYV
|  .. |.| ..         ||.|||..|||   |                .|..|||| . .  ....  .   ..           . ...||. . 
IARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWM

SPEQEAGH----------------QYNERADVYSLGIILFELYF---PFSTRMERVKVLE-------DIKSNRRLPKEFK---------ENLHNE----A
.||   |.                .|.|..|||| ||.|.|..    |..  ...  ..         . ....|. . .          . ..     .
APEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMK

KLVELMLKP-ISDRPSSSEIKEID
|| .   ..  ..||| .||... 
KLMQDCWDHDPEKRPSFQEILKRL
Kinase AqueK197.AA PKR 1022-1173 38 8.3e-20 67.51 In-house 132-272 (272) Show / Hide 
Range on Protein: 1022-1173
Range on HMM: 132-272/272
Sequence Identity: 38% (58 aa)

ILDAVIYMHDKDYIHCDLKPSNILFAMNDSIKVGDFGLVKQNAATKHSAPQTDVQGSHTSEIGTLFYVSPEQEAGHQYNERADVYSLGIILFELYFPFST
|   | |.| |  || |||||||    .  ||.||||||         | . | . | |   ||| |.||||   ..|    |.| ||.|| ||     |
IVKGVDYIHSKKLIHRDLKPSNIFLVDERHIKIGDFGLV--------TALKNDGK-SRTRRKGTLQYMSPEQIFSQHYGKEVDIYALGLILAELLHVCFT

RMERVKVLEDIKSNRRLPKEFKENLHNEAKLVELMLKPISDRPSSSEIKEID
 .|..|  ||..        | .     . |  |. |   |||  |||    
EFEKIKFFEDLRDGDFSNDIFDN--KEKTLLQKLLSKKPKDRPNTSEILRTL
Kinase AqueK197.AA ULK 1022-1151 20 4.1e-19 63.42 In-house 139-303 (329) Show / Hide 
Range on Protein: 1022-1151
Range on HMM: 139-303/329
Sequence Identity: 20% (36 aa)

ILDAVIYMHDKDYIHCDLKPSNILFAMND------------SIKVGDFGLVKQ---N---AATKHSAP-QTDVQGSHTSEI---GTLFYVSPE--QEA--
|| .  ..|.. .||.|.||.|||   ..             .|..|||. |.   .   ..  ...  .              ||  | .|.  |.   
ILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQMMMTCVNE----------KRLCGTPLYMAPQILQGQGE

GHQYNER-ADVYSLGIILFELYF---PFSTRMERVKVLEDIKSNRR-----------LPKEFK-----ENLHNEAK
. .|..  .|..|||.|..|. .   ||..   .  .|  |.....            | .|.      .. .| |
QKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQISPECK
Kinase AqueK197.AA PEK-Unclassified 1080-1142 40 8.6e-18 58.05 In-house 731-803 (835) Show / Hide 
Range on Protein: 1080-1142
Range on HMM: 731-803/835
Sequence Identity: 40% (30 aa)

TSEIGTLFYVSPEQE-----------AGHQYNERADVYSLGIILFELYFPFSTRMERVKVLEDIKSNRRLPKEF
|| .||  | |.|||            .  || |.|.||.|||.|..  .. | ||||| .  .|    ||| |
TSTCGTYTYSSNEQESQKKVRIKAHFQADFYNHRTDIYSVGIIFFQMFHQMNTTMERVKTIQNCK-KGELPKHF
Kinase AqueK197.AA PEK 1022-1066 34 5.1e-13 38.6 In-house 451-519 (758) Show / Hide 
Range on Protein: 1022-1066
Range on HMM: 451-519/758
Sequence Identity: 34% (24 aa)

ILDAVIYMHDKDYIHCDLKPSNILFAMNDS------------------------IKVGDFGLVKQNAAT
|...| | | |  || ||||||| |.| .                         ||.||||||..  ..
ICEGVNYIHSKGMIHRDLKPSNIFFSMDSQHHQQSSFSNISSSFEENSDGGHQIIKIGDFGLVTDHTIV
S_TKc AqueK197.AA S_TKc 1021-1175 16 6.9e-09 -46.56 SMART 1-231 (231) Show / Hide 
Range on Protein: 1021-1175
Range on HMM: 1-231/231
Sequence Identity: 16% (44 aa)

X---------------------------------------------------------------------------------------------------
                                                                                                    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIKEHIRREIQILKKHHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPEHARFYM

--ILDAVIYMHDKDYIHCDLKPSNILFAMNDSIKVGDFGLVKQNAATKHSAPQTDVQGSHTSEIGTLFYVSPEQEAGHQYNE-RADVYSLGIILFELYF-
  |..|. |.|..  ||.||||.|||.     ||..|||| .|                 |. .||..|..||     .|.  ..|..|.|.||.|..  
YQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----------------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCG

--PFSTRMERVKVLEDIKSNRRLPKEFKENLHNEAK-LVELMLK-PISDRPSSSEIKE-------IDAF
  ||.   .  .... |.               ||| ... .|.   ..||.  |. .          |
YPPFP---QMQMMFKKIG-------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK197.AA PEK-Unclassified 1022-1062 44 5e-07 19.37 In-house 622-664 (835) Show / Hide 
Range on Protein: 1022-1062
Range on HMM: 622-664/835
Sequence Identity: 44% (19 aa)

ILDAVIYMHDKD-YIHCDLKPSNILFAMN-DSIKVGDFGLVKQ
|. |  . |    ..| |.|| ||    |   ||.|||||||.
IIKALYHIHHQCKMVHRDIKPHNIFVCQNPMQIKIGDFGLVKK
TyrKc AqueK197.AA TyrKc 1021-1175 13 0.000666 -159.52 SMART 1-280 (280) Show / Hide 
Range on Protein: 1021-1175
Range on HMM: 1-280/280
Sequence Identity: 13% (39 aa)

XILDAVI---------------------------------------------------------------------------------------------
  |. ..                                                                                             
ITLGKKLGEGAFGEVYKGTWKIQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKLCMK

--------------YMHDKDYIHCDLKPSNILFAMNDSIKVGDFGLVKQNAAT---KHSAPQTDVQGSHTSEI--GTLFYVSPEQEAGHQYNERADVYSL
              | |.| .|| ||   |.| . |  .|..|||| .           . .. .. .| ..     .   .||    . ...  ||.| 
DLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQG-ESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDVWSF

GIILFELY----FPFSTR----MERVKVLEDIKSNRRLPKEFK--ENL---HNEAKLVELMLK----PISDRPSSSEIKEIDAF
|. ..|..     | .      |.   |.|..|. .|.|.     . .   .  ... ..|..      .|||. |||  .. |
GVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYP-MSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF