Gene AqueK214 (A.queenslandica)
AqueK214
Species: A.queenslandica
Alias: AqueK214
External Links:
Annotation:
Sequence
Name | Sequence Type | Origin | Length | Description | Download |
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AqueK214.AA | Protein | None | 351 | None | Fasta, JSON |
AqueK214.kin_dom | Protein Kinase Domain | None | 283 | None | Fasta, JSON |
Protein domains of AqueK214.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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S_TKc | AqueK214.AA | S_TKc | 4-347 | 16 | 8.9e-20 | 72.94 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 4-347 Range on HMM: 1-231/231 Sequence Identity: 16% (60 aa) YVLYGEISSKPWCTVFKGRRKRTVEYV---SIHKYSTELYETLSHNVNQLSHLDHTHILQFLEWYRSPQHIWLVTELASV--GTLADLMSADGP------ | . .| . .|.|.| |.| ..| |. |.. .. |.. .| .| ........ .|...|.|... |.| |.. |. YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP VPLESIPSFVSDILSGLNHAHLMGVVIRDLCPAKIYLDACGNLKLSDFSLAIDLKKNKDDDDNINVMKDIEQFYSSIININEKLLVQNNDADSTKSVDIP | . ... |...|.. | .|.. ||| |. | || ..|..|| || | FPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---------------------------------------------- GVNSLTQQHSIQPPSNHKDSAHSPLLALNAHHFSSPSLPSPFYLSPESIEHSLFSI-GTDLWSIGVIMYELWTGKCPFSGDTHTDLVHSIISYEPVEIKE . .|.|..|| . .. | ||.|.|.||. .|. ||. .. . . | ----------------------------------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG--------- WRESNSTSNTSSSNSTGLEDHLLCVSYQVMKLMCGLLVKDPSKRHGWNDVIP-------IEGL | .. .....|.|||.|| . .. . . -------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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Kinase | AqueK214.AA | AGC | 105-335 | 16 | 1.1e-19 | 46.1 | In-house | 162-373 (395) | Show / Hide |
Range on Protein: 105-335 Range on HMM: 162-373/395 Sequence Identity: 16% (48 aa) ILSGLNHAHL-MGVVIRD-LCPAKIYLDACGNLKLSDFSLAIDLKKNK-----------------------------------------------DDDDN |...| . | ||.. || | | | ||. |..||.|| |. ..... ...| IVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFGLCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDR INVMKDIEQFYSSIININEKLLVQNNDADSTKSVDIPGVNSLTQQHSIQPPSNHKDSAHSPLLALNAHHFSSPSLPSPFYLSPESIEHSLFSIGTDLWS- . . | .| |..|| . . | || TWTFCG------------------------------------------------------------------PC--TPEYMAPEIL----YGKACDWWSF -IGVIMYELWTGKCPFSGDT----------HTDLVHSIIS-----YEPVEIKEWRESNSTSNTSSSNSTGLEDHLLCVSYQVMKLMCGLLVKDPSKR |..|||. ||. ||.||. . .. ..|.. ..|.. ... .. .| . . |. .||.|||.|| GLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDP-------------QFPEDRWFSPEAKDLIKKLLCKDPEKR |
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Kinase | AqueK214.AA | TKL | 10-270 | 13 | 4.3e-15 | 50.8 | In-house | 1-290 (364) | Show / Hide |
Range on Protein: 10-270 Range on HMM: 1-290/364 Sequence Identity: 13% (46 aa) ISSKPWCTVFKGRRKRTV--------EYVSIHKYSTE------------------------------LYETLSHNVNQLSHLDHTHILQFLE-------- | | ..|.||. . . . | . |.... . ... ....| |.| .|.||. IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG -WYRSP----QHIWLVTELASVGTLADLMSADGPVPLESIPSFVSDILSGLNHAHLMG--------VVIRDLCPAKIYLDACGN--------------LK . .| ....|.|... |.| ... .. . ... || .|.|. | |. .. ||| .. | .| .. .| CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCK LSDFSLAIDLKKNKDDDDNINVMKDIEQFYSSIININEKLLVQNNDADSTKSVDIPGVNSLTQQHSIQPPSNHKDSAHSPLLALNAHHFSSPSLPSPFYL ..|| |. ........ |. . |. .. . .. | . ... .| .. ICDFGLSRFMSQSGNMNDTMTTMME-SA---------------------------------------------------E-HQ-NNRKTTMTQCGTPRWM SPESIEHS----------------LFSIGTDLWSIGVIMYELWTGKCPFS .|| .. . .| .| .| |....|. |.. |.. APEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYY |
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Kinase | AqueK214.AA | Pkinase | 50-140 | 29 | 2e-14 | 52.1 | Pfam | 54-156 (293) | Show / Hide |
Range on Protein: 50-140 Range on HMM: 54-156/293 Sequence Identity: 29% (30 aa) LSHLDHTHILQFLEWYRSPQHIWLVTELASVG----TLADLMS--ADGPV--PLESIPSFVSDILSGLNHAHLMGVVIRDLCPAKIYLDACGNL----KL . .|.| .|.....|.....||..|.|.. | |.|..| ..|.. . . . ... ||.||.. | ||.. ||| |. | .| |.. |. MKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKI SDF .|| CDF |
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Kinase | AqueK214.AA | Ciliate-E2-Unclassified | 50-347 | 13 | 1.2e-13 | 43.76 | In-house | 75-352 (352) | Show / Hide |
Range on Protein: 50-347 Range on HMM: 75-352/352 Sequence Identity: 13% (48 aa) LSHLDHTHILQFLEWYRSPQHIWLVTELASVGTLADLMSADGP-----------------VPLESIP-----SFVSDILSGLNHAHLMG-VVIRDLCPAK |....| .|. .... .. |.| .|.|.. |.| . .. . .. . . . ||.||.. | . .. ||. | LLNHPHPFIVKMFYCFQDKQNIYIVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPEN IYLDACG---NLKLSDFSLAIDLKKNKDDDDNINVMKDIEQFYSSIININEKLLVQNNDADSTKSVDIPGVNSLTQQHSIQPPSNHKDSAHSPLLALNAH | .| | ..|..||.... ...| ..| . . . . .. . . ILFDNNGKNYYIKIIDFGISKKYQQNNNCD-TNQ----------------------------------------------------Q-----QKMQIWKQ HFSSPSLPSPFYL----SPESIEHSLFS----IGTDLWSIGVIMYELWTGKCPFSGDTHTD---------------LVHSIISYEPVEIK--EWRESNST . .. .| |. .|| .. . . | || |||.||. .|..||.. . .. ....| ..... .|.. QMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQKNIQFPKFPWQQ---- SNTSSSNSTGLEDHLLCVSYQVM--------KLMCGLLVKDPSKRHGWNDVIPIEGL ..... .|.. .|.|.|.|| ...... . -----------------IPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF |
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Kinase | AqueK214.AA | ULK | 17-154 | 17 | 1e-12 | 40.8 | In-house | 14-200 (329) | Show / Hide |
Range on Protein: 17-154 Range on HMM: 14-200/329 Sequence Identity: 17% (33 aa) TVFKGRRKRT----VEYVSIHKYSTELYETLSHN-------------VNQLSHLD--------HTHILQFLEWYRSPQH--IWLVTELASVGTLADLMSA .|.||| |.| .|.| . . . . ... . . |. | .| ....|.....| |....|. |.| .... KVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIMEYCNGGDLEQYIKK DGPVPLES----------IPSFVSDILSGLNHAHLMGVVIRDLCPAKIYLDAC------------GNLKLSDFSLAIDLKKNKDDDD ... |.. . .| .||.|. . | .... ||. |. | .. | ||..|| .| . ....... NKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ |
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Kinase | AqueK214.AA | Ciliate-E2 | 232-342 | 17 | 1.6e-12 | 39.31 | In-house | 250-360 (365) | Show / Hide |
Range on Protein: 232-342 Range on HMM: 250-360/365 Sequence Identity: 17% (26 aa) SPFYLSPESIE---------HSLFSIGTDLWSIGVIMYELWTGKCPFSGDTHTDLVHSIISYEPVEIKEWRESNSTSNTSSSNSTGLEDHLLC------- .| |..|| .. . . |.||.|||.||. .|| || .. .. | TPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF---------------------------------------QQQIKQCKIDFPCP ------------------VSYQVMKLMCG----LLVKDPSKRHG-WNDVI .| ... |. .|.|||.|| . |.... EWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQIL |
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Kinase | AqueK214.AA | ULK | 232-347 | 17 | 6e-12 | 38.07 | In-house | 214-329 (329) | Show / Hide |
Range on Protein: 232-347 Range on HMM: 214-329/329 Sequence Identity: 17% (24 aa) SPFYLSPESIE----HSLFS-IGTDLWSIGVIMYELWTGKCPFSGDTHTDLVHSII-SY--EPVEIKEWRESNSTSNTSSSNSTGLEDHLLC-------- .| | .|. .. . .. .|.||.|.|.||. .||.||.. .|... || . | .... . . TPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQ---------------------QIKKQPLQFPK ------VSYQVMKLMCGLLVKDPSKRHGWNDVIPIEGL .| .. | ..|..|...| | ... .. . DGNDPQISPECKDLIRRMLQYDEKDRISWEELFNHPWF |
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Kinase | AqueK214.AA | NuaK | 50-142 | 33 | 8.7e-12 | 26.72 | In-house | 53-145 (252) | Show / Hide |
Range on Protein: 50-142 Range on HMM: 53-145/252 Sequence Identity: 33% (31 aa) LSHLDHTHILQFLEWYRSPQHIWLVTELASVGTLADLMSADGPVPLESIPSFVSDILSGLNHAHLMGVVIRDLCPAKIYLDACGNLKLSDFSL .| |.| || . | . . . | .| | || | | | .| . .| . . | | | . |. ... ||| | ||. .| | || | MSSLNHPHIIHIYEVFENKDKIVIVMEYASGGELYDYISECKSLPEREARHFFRQIVSAVHYCHKHRICHRDLKLENILLDQNCNAKIADFGL |
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Kinase | AqueK214.AA | CAMK | 50-151 | 17 | 1.7e-11 | 32.59 | In-house | 85-251 (425) | Show / Hide |
Range on Protein: 50-151 Range on HMM: 85-251/425 Sequence Identity: 17% (30 aa) LSH-------LDHTHILQFLEWYRS-------------------PQHIWLVT---ELASVG----TLADLMSADGP---------------VPLESIPSF ... ||| .|....|.| . ..|...|. |..| | | | . |. .. . . MKKLQGIGNKLDHPNIIKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRY VSDILSGLNHAHLMGVVIRDLCPAKIYLDAC-----------------GNLKLSDFSLAIDLKKNKD . |.|.... | ...| ||| | | || .|.|..|| .|. ...... FRQICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGEN |
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Kinase | AqueK214.AA | ULK | 232-290 | 22 | 3.4e-11 | 36.02 | In-house | 210-285 (324) | Show / Hide |
Range on Protein: 232-290 Range on HMM: 210-285/324 Sequence Identity: 22% (17 aa) SPFYLSPESIE----HSLFS-IGTDLWSIGVIMYELWTGKCPFSGDTHTDLVH---SI----------ISYEPVEIK .| | .|. .. . .. . .|.||.|.|.||. .||.||... .|... . | ..|.... TPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFP |
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Kinase | AqueK214.AA | GIN4 | 53-143 | 26 | 5e-11 | 31.03 | In-house | 91-182 (293) | Show / Hide |
Range on Protein: 53-143 Range on HMM: 91-182/293 Sequence Identity: 26% (24 aa) LDHTHILQFLEWYRSPQHIWLVTELASVGTLADLMSADGPVPLESIPSFVSDILSGLNHAHLMGVVIRDLCPAKIYLDACGN-LKLSDFSLA ..|. ... . . . ..|| | | | | ... ||.| . |. |. | .... ||| | . || | .|. || .| ISHPNVMRLYDVWETNNDLYLVLEYAEKGELFNYLVDHGPLPEREAIHYFRQIIIGVSYCHAFNICHRDLKPENLLLDHKYNRIKIADFGMA |
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Kinase | AqueK214.AA | ULK | 49-154 | 19 | 3.4e-10 | 32.42 | In-house | 66-196 (324) | Show / Hide |
Range on Protein: 49-154 Range on HMM: 66-196/324 Sequence Identity: 19% (26 aa) QLSHLDHTH--ILQFLEWYRSPQH--IWLVTELASVGTLADLMSADGPVPLES----------IPSFVSDILSGLNHAHLMGVVIRDLCPAKIYLDA--- .| .| | . | ....|.....| |....|. |.| ... ... |. . .| .|..|. . | .... ||. |. | . KLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCNGGDLEQYIKKNKKLPE-TEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQP ---------CGNLKLSDFSLAIDLKKNKDDDD | ||..|| .| . .| ... KTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQ |
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Kinase | AqueK214.AA | Pkinase | 232-335 | 24 | 8.6e-10 | 35.7 | Pfam | 174-281 (293) | Show / Hide |
Range on Protein: 232-335 Range on HMM: 174-281/293 Sequence Identity: 24% (27 aa) SPFYLSPESIE-HSLFSIGTDLWSIGVIMYELWTGKCPFSGD------THTDLVHSIISYEPVEIKEWRESNSTSNTSSSNSTGLEDHLLCVSYQVMKLM .|.|..|| | .. . | ||.|.|.||. .|. ||.|. .. .. | . .. . .| |.|..... .. .. .| ... TPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRH-WHF-HWTF-HNWSEECKDFI CGLLVKDPSKR ...| |||.|| KWCLCKDPKKR |
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Kinase | AqueK214.AA | Ciliate-E2a | 50-122 | 27 | 2e-08 | 20.94 | In-house | 53-128 (275) | Show / Hide |
Range on Protein: 50-122 Range on HMM: 53-128/275 Sequence Identity: 27% (21 aa) LSHLDHTHILQFLEWYRSPQHIWLVTELASVGTLADLMSADGPVPLE--SIPSFVSDILS-GLNHAHLMGVVIRDL .. ||| .|... | | . ... ||.|. . |.| | .. .. | | .. .|. ||.. | ... ||| MRQLDHPNIIKLYEVYEDENNYYLVMEYCEGGELYDKIKQCKRFFEEIQEICDIMQQLLWQGLHYMHQRNIMHRDL |
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Kinase | AqueK214.AA | Ciliate-E2a | 251-276 | 53 | 5.6e-08 | 19.6 | In-house | 198-223 (275) | Show / Hide |
Range on Protein: 251-276 Range on HMM: 198-223/275 Sequence Identity: 53% (14 aa) DLWSIGVIMYELWTGKCPFSGDTHTD |.||.|||.| | .|| || | |... DMWSCGVIFYILLCGKPPFKGKTYNE |
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Kinase | AqueK214.AA | CAMK | 250-335 | 18 | 4.8e-07 | 17.99 | In-house | 315-413 (425) | Show / Hide |
Range on Protein: 250-335 Range on HMM: 315-413/425 Sequence Identity: 18% (21 aa) TDLWSIGVIMYELWTGKCPFSGD-------------THTDLVHSIISYEPV-EIKEWRE----SNSTSNTSSSNSTGLEDHLLCVSYQ--------VMKL .| ||.|||.| . .|. || || . .| . |.. . . ... . . .. ..| . .. | CDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNY-------------GPEWWDDISDEFHHFVSQECKDL MCGLLVKDPSKR ...|..||.|| IRKMLQVDPEKR |
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Kinase | AqueK214.AA | Ciliate-E2 | 48-152 | 19 | 7.8e-07 | 19.47 | In-house | 84-212 (365) | Show / Hide |
Range on Protein: 48-152 Range on HMM: 84-212/365 Sequence Identity: 19% (26 aa) NQLSHLDHTHILQFLEWYR--SPQHIWLVTELASVGTLADLMS------------ADGPVPLESIPSFVSDILS---------------GLNHAHLMG-V | |..|.| .|... |.. . ..| ||.|... |.| |.. . .. .. | . ||. .|.. | . . NILEQLNHPNIIKMYECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNI VIRDLCPAKIYLDACGNLKLSDFSLAIDLKKNKDD . ||. | | . .|..|| |. ..... .. IHRDIKPENILF-----IKIIDFGLSKKYDDDNQN |
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TyrKc | AqueK214.AA | TyrKc | 4-347 | 14 | 9.9e-07 | -113.83 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 4-347 Range on HMM: 1-280/280 Sequence Identity: 14% (53 aa) YVLYGEISSKPWCTVFKGRRKRTVEYV---SIHKYSTELYETLSHNVNQLSHL--DHTHILQFLEWYRSP-------QHIWLVTELASVGTLADLMSADG .| .. . ..|.||. | . | ...... | . . . ...| .| .|.... ... . ...|.|... | | | . . ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR P-VPLESIPSFVSDILSGLNHAHLMGVVIRDLCPAKIYLDACGNLKLSDFSLAIDLKKN-KDDDDNINVMKDIEQFYSSIININEKLLVQNNDADSTKSV | .... || .| .| .. | .... ||| . ... . | ||| |. |.. . PKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQG------------------------------------- DIPGVNSLTQQHSIQPPSNHKD---SAH--SPLLALNAHHFSSPSLPSPFYLSPESIEHSLFSIGTDLWSIGVIMYELWT-GKCPFSG-----DTHTDLV .| ... |. ..||.| .. |.. .| || || |.|. | |. | .| . .... -------------ESKDYYRKKEHKGGKTMLPI----------------RWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVI HSIISY---EPVEI----KEWRESNSTSNTSSSNSTGLEDHLLCVSYQVMKLMCGLLVKDPSKRHGWNDVIPIEGL . . . .. . | . . ..| ||..| ... .| . EYVKQGYRMPQPPNDYPMS----------------------FVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF |
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Kinase | AqueK214.AA | NuaK | 251-281 | 41 | 6e-06 | 11.14 | In-house | 181-211 (252) | Show / Hide |
Range on Protein: 251-281 Range on HMM: 181-211/252 Sequence Identity: 41% (13 aa) DLWSIGVIMYELWTGKCPFSGDTHTDLVHSI | || ||..| . | || |. . || | DCWSLGVLLYTMVYGTMPFDGHDFKHLVKQI |
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Kinase | AqueK214.AA | Pkinase_Tyr | 236-271 | 39 | 4.4e-05 | 17.83 | Pfam | 181-218 (270) | Show / Hide |
Range on Protein: 236-271 Range on HMM: 181-218/270 Sequence Identity: 39% (15 aa) LSPESIEHSLFSIGTDLWSIGVIMYELWT-GKCP-FSG ..||.| .. |.. .| || || |.|. | |. | . | MAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPG |
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Kinase | AqueK214.AA | GIN4 | 232-272 | 38 | 0.000178 | 9.74 | In-house | 197-238 (293) | Show / Hide |
Range on Protein: 232-272 Range on HMM: 197-238/293 Sequence Identity: 38% (16 aa) SPFYLSPESIEHSLFSIGT-DLWSIGVIMYELWTGKCPFSGD || | .|| . . . | || |||.. | ||. || . SPHYAAPEIVMGIPYHGFASDVWSCGVILFALLTGHLPFDEE |
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Kinase | AqueK214.AA | Ciliate-E2a | 313-335 | 39 | 0.132499 | 0.52 | In-house | 241-263 (275) | Show / Hide |
Range on Protein: 313-335 Range on HMM: 241-263/275 Sequence Identity: 39% (9 aa) LLCVSYQVMKLMCGLLVKDPSKR ....| . . || ..|.|||.|| WEKCSKECKDLMKKMLEKDPKKR |