AqueK214

Species: A.queenslandica
Alias: AqueK214
External Links:
Annotation:

Classification

Group: Other
Family: ULK
Subfamily: ULK

Sequence

Name Sequence Type Origin Length Description Download
AqueK214.AA Protein None 351 None Fasta, JSON
AqueK214.kin_dom Protein Kinase Domain None 283 None Fasta, JSON

Protein domain

Protein domains of AqueK214.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc AqueK214.AA S_TKc 4-347 16 8.9e-20 72.94 SMART 1-231 (231) Show / Hide
Range on Protein: 4-347
Range on HMM: 1-231/231
Sequence Identity: 16% (60 aa)

YVLYGEISSKPWCTVFKGRRKRTVEYV---SIHKYSTELYETLSHNVNQLSHLDHTHILQFLEWYRSPQHIWLVTELASV--GTLADLMSADGP------
| .  .| .    .|.|.| |.| ..|    |.       |..   .. |.. .| .| ........ .|...|.|...   |.| |..   |.      
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP

VPLESIPSFVSDILSGLNHAHLMGVVIRDLCPAKIYLDACGNLKLSDFSLAIDLKKNKDDDDNINVMKDIEQFYSSIININEKLLVQNNDADSTKSVDIP
 |   . ...  |...|.. | .|.. ||| |. | ||   ..|..|| ||  |                                              
FPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----------------------------------------------

GVNSLTQQHSIQPPSNHKDSAHSPLLALNAHHFSSPSLPSPFYLSPESIEHSLFSI-GTDLWSIGVIMYELWTGKCPFSGDTHTDLVHSIISYEPVEIKE
                                  .    .|.|..|| .    ..    | ||.|.|.||. .|. ||.  ..  . . |          
----------------------------------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG---------

WRESNSTSNTSSSNSTGLEDHLLCVSYQVMKLMCGLLVKDPSKRHGWNDVIP-------IEGL
                         | ..  .....|.|||.|| .  ..          . .
-------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase AqueK214.AA AGC 105-335 16 1.1e-19 46.1 In-house 162-373 (395) Show / Hide
Range on Protein: 105-335
Range on HMM: 162-373/395
Sequence Identity: 16% (48 aa)

ILSGLNHAHL-MGVVIRD-LCPAKIYLDACGNLKLSDFSLAIDLKKNK-----------------------------------------------DDDDN
|...| . |  ||.. || | |  | ||. |..||.|| |.  .....                                               ...| 
IVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFGLCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDR

INVMKDIEQFYSSIININEKLLVQNNDADSTKSVDIPGVNSLTQQHSIQPPSNHKDSAHSPLLALNAHHFSSPSLPSPFYLSPESIEHSLFSIGTDLWS-
 . .                                                                    |   .| |..|| .     .   | || 
TWTFCG------------------------------------------------------------------PC--TPEYMAPEIL----YGKACDWWSF

-IGVIMYELWTGKCPFSGDT----------HTDLVHSIIS-----YEPVEIKEWRESNSTSNTSSSNSTGLEDHLLCVSYQVMKLMCGLLVKDPSKR
  |..|||. ||. ||.||.          . .. ..|..      ..|..   ...              ..    .| . . |. .||.|||.||
GLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDP-------------QFPEDRWFSPEAKDLIKKLLCKDPEKR

Kinase AqueK214.AA TKL 10-270 13 4.3e-15 50.8 In-house 1-290 (364) Show / Hide
Range on Protein: 10-270
Range on HMM: 1-290/364
Sequence Identity: 13% (46 aa)

ISSKPWCTVFKGRRKRTV--------EYVSIHKYSTE------------------------------LYETLSHNVNQLSHLDHTHILQFLE--------
| |   ..|.||. . .         . | . |....                              . ...   ....| |.| .|.||.         
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

-WYRSP----QHIWLVTELASVGTLADLMSADGPVPLESIPSFVSDILSGLNHAHLMG--------VVIRDLCPAKIYLDACGN--------------LK
 .  .|     ....|.|... |.| ...       .. . ... || .|.|. | |.        .. ||| .. | .|  ..              .|
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCK

LSDFSLAIDLKKNKDDDDNINVMKDIEQFYSSIININEKLLVQNNDADSTKSVDIPGVNSLTQQHSIQPPSNHKDSAHSPLLALNAHHFSSPSLPSPFYL
..|| |. ........ |. . |.  ..                                                   . .. | .  ...   .| ..
ICDFGLSRFMSQSGNMNDTMTTMME-SA---------------------------------------------------E-HQ-NNRKTTMTQCGTPRWM

SPESIEHS----------------LFSIGTDLWSIGVIMYELWTGKCPFS
.|| .. .                 .|  .| .| |....|. |.. |..
APEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYY

Kinase AqueK214.AA Pkinase 50-140 29 2e-14 52.1 Pfam 54-156 (293) Show / Hide
Range on Protein: 50-140
Range on HMM: 54-156/293
Sequence Identity: 29% (30 aa)

LSHLDHTHILQFLEWYRSPQHIWLVTELASVG----TLADLMS--ADGPV--PLESIPSFVSDILSGLNHAHLMGVVIRDLCPAKIYLDACGNL----KL
. .|.| .|.....|.....||..|.|..  |     |.|..|  ..|..  . . . ...  ||.||.. | ||.. ||| |. | .|  |..    |.
MKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKI

SDF
.||
CDF

Kinase AqueK214.AA Ciliate-E2-Unclassified 50-347 13 1.2e-13 43.76 In-house 75-352 (352) Show / Hide
Range on Protein: 50-347
Range on HMM: 75-352/352
Sequence Identity: 13% (48 aa)

LSHLDHTHILQFLEWYRSPQHIWLVTELASVGTLADLMSADGP-----------------VPLESIP-----SFVSDILSGLNHAHLMG-VVIRDLCPAK
|....| .|. .... .. |.| .|.|..  |.| . ..  .                  .. . .       .   ||.||.. |  . .. ||. |  
LLNHPHPFIVKMFYCFQDKQNIYIVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPEN

IYLDACG---NLKLSDFSLAIDLKKNKDDDDNINVMKDIEQFYSSIININEKLLVQNNDADSTKSVDIPGVNSLTQQHSIQPPSNHKDSAHSPLLALNAH
| .|  |   ..|..||.... ...| ..| . .                                                    .     . .. . .
ILFDNNGKNYYIKIIDFGISKKYQQNNNCD-TNQ----------------------------------------------------Q-----QKMQIWKQ

HFSSPSLPSPFYL----SPESIEHSLFS----IGTDLWSIGVIMYELWTGKCPFSGDTHTD---------------LVHSIISYEPVEIK--EWRESNST
. ..    .| |.    .|| ..    .    .  | || |||.||. .|..||.. . ..                ....|   .....  .|..    
QMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQKNIQFPKFPWQQ----

SNTSSSNSTGLEDHLLCVSYQVM--------KLMCGLLVKDPSKRHGWNDVIPIEGL
                 .....         .|.. .|.|.|.|| ......    .
-----------------IPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF

Kinase AqueK214.AA ULK 17-154 17 1e-12 40.8 In-house 14-200 (329) Show / Hide
Range on Protein: 17-154
Range on HMM: 14-200/329
Sequence Identity: 17% (33 aa)

TVFKGRRKRT----VEYVSIHKYSTELYETLSHN-------------VNQLSHLD--------HTHILQFLEWYRSPQH--IWLVTELASVGTLADLMSA
.|.||| |.|    .|.| . . . .     ...             .  .  |.        | .| ....|.....|  |....|.   |.| .... 
KVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIMEYCNGGDLEQYIKK

DGPVPLES----------IPSFVSDILSGLNHAHLMGVVIRDLCPAKIYLDAC------------GNLKLSDFSLAIDLKKNKDDDD
... |..           . .|  .||.|. . | .... ||. |. | ..              | ||..|| .|  . .......
NKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

Kinase AqueK214.AA Ciliate-E2 232-342 17 1.6e-12 39.31 In-house 250-360 (365) Show / Hide
Range on Protein: 232-342
Range on HMM: 250-360/365
Sequence Identity: 17% (26 aa)

SPFYLSPESIE---------HSLFSIGTDLWSIGVIMYELWTGKCPFSGDTHTDLVHSIISYEPVEIKEWRESNSTSNTSSSNSTGLEDHLLC-------
.| |..|| ..         .   .   |.||.|||.||. .|| ||                                       .. .. |       
TPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF---------------------------------------QQQIKQCKIDFPCP

------------------VSYQVMKLMCG----LLVKDPSKRHG-WNDVI
                  .| ... |.      .|.|||.|| . |....
EWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQIL

Kinase AqueK214.AA ULK 232-347 17 6e-12 38.07 In-house 214-329 (329) Show / Hide
Range on Protein: 232-347
Range on HMM: 214-329/329
Sequence Identity: 17% (24 aa)

SPFYLSPESIE----HSLFS-IGTDLWSIGVIMYELWTGKCPFSGDTHTDLVHSII-SY--EPVEIKEWRESNSTSNTSSSNSTGLEDHLLC--------
.| | .|. ..    .  ..   .|.||.|.|.||. .||.||..   .|... || .    | ....                     . .        
TPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQ---------------------QIKKQPLQFPK

------VSYQVMKLMCGLLVKDPSKRHGWNDVIPIEGL
      .| ..  |  ..|..|...|  | ... .. .
DGNDPQISPECKDLIRRMLQYDEKDRISWEELFNHPWF

Kinase AqueK214.AA NuaK 50-142 33 8.7e-12 26.72 In-house 53-145 (252) Show / Hide
Range on Protein: 50-142
Range on HMM: 53-145/252
Sequence Identity: 33% (31 aa)

LSHLDHTHILQFLEWYRSPQHIWLVTELASVGTLADLMSADGPVPLESIPSFVSDILSGLNHAHLMGVVIRDLCPAKIYLDACGNLKLSDFSL
.| |.| || .  | . . . | .| | || | | | .|  . .| . .  |   | | .   |. ... |||    | ||. .| |  || |
MSSLNHPHIIHIYEVFENKDKIVIVMEYASGGELYDYISECKSLPEREARHFFRQIVSAVHYCHKHRICHRDLKLENILLDQNCNAKIADFGL

Kinase AqueK214.AA CAMK 50-151 17 1.7e-11 32.59 In-house 85-251 (425) Show / Hide
Range on Protein: 50-151
Range on HMM: 85-251/425
Sequence Identity: 17% (30 aa)

LSH-------LDHTHILQFLEWYRS-------------------PQHIWLVT---ELASVG----TLADLMSADGP---------------VPLESIPSF
...       ||| .|....|.| .                   ..|...|.   |..| |     | |   . |.               .. .    .
MKKLQGIGNKLDHPNIIKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRY

VSDILSGLNHAHLMGVVIRDLCPAKIYLDAC-----------------GNLKLSDFSLAIDLKKNKD
.  |.|.... | ...| ||| |  | ||                   .|.|..|| .|. ......
FRQICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGEN

Kinase AqueK214.AA ULK 232-290 22 3.4e-11 36.02 In-house 210-285 (324) Show / Hide
Range on Protein: 232-290
Range on HMM: 210-285/324
Sequence Identity: 22% (17 aa)

SPFYLSPESIE----HSLFS-IGTDLWSIGVIMYELWTGKCPFSGDTHTDLVH---SI----------ISYEPVEIK
.| | .|. ..    .  .. . .|.||.|.|.||. .||.||...  .|...   .           | ..|....
TPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFP

Kinase AqueK214.AA GIN4 53-143 26 5e-11 31.03 In-house 91-182 (293) Show / Hide
Range on Protein: 53-143
Range on HMM: 91-182/293
Sequence Identity: 26% (24 aa)

LDHTHILQFLEWYRSPQHIWLVTELASVGTLADLMSADGPVPLESIPSFVSDILSGLNHAHLMGVVIRDLCPAKIYLDACGN-LKLSDFSLA
..|. ...  . .   . ..|| | |  | | ...   ||.|      .   |. |.   | .... ||| |  . ||   | .|. || .|
ISHPNVMRLYDVWETNNDLYLVLEYAEKGELFNYLVDHGPLPEREAIHYFRQIIIGVSYCHAFNICHRDLKPENLLLDHKYNRIKIADFGMA

Kinase AqueK214.AA ULK 49-154 19 3.4e-10 32.42 In-house 66-196 (324) Show / Hide
Range on Protein: 49-154
Range on HMM: 66-196/324
Sequence Identity: 19% (26 aa)

QLSHLDHTH--ILQFLEWYRSPQH--IWLVTELASVGTLADLMSADGPVPLES----------IPSFVSDILSGLNHAHLMGVVIRDLCPAKIYLDA---
.| .| | .  | ....|.....|  |....|.   |.| ...  ... |.            . .|  .|..|. . | .... ||. |. | .     
KLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCNGGDLEQYIKKNKKLPE-TEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQP

---------CGNLKLSDFSLAIDLKKNKDDDD
          | ||..|| .|  . .|  ...
KTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQ

Kinase AqueK214.AA Pkinase 232-335 24 8.6e-10 35.7 Pfam 174-281 (293) Show / Hide
Range on Protein: 232-335
Range on HMM: 174-281/293
Sequence Identity: 24% (27 aa)

SPFYLSPESIE-HSLFSIGTDLWSIGVIMYELWTGKCPFSGD------THTDLVHSIISYEPVEIKEWRESNSTSNTSSSNSTGLEDHLLCVSYQVMKLM
.|.|..|| |  ..  .   | ||.|.|.||. .|. ||.|.      ..  ..  | . .. .  .|  |.|.....   .. ..     .|    ...
TPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRH-WHF-HWTF-HNWSEECKDFI

CGLLVKDPSKR
...| |||.||
KWCLCKDPKKR

Kinase AqueK214.AA Ciliate-E2a 50-122 27 2e-08 20.94 In-house 53-128 (275) Show / Hide
Range on Protein: 50-122
Range on HMM: 53-128/275
Sequence Identity: 27% (21 aa)

LSHLDHTHILQFLEWYRSPQHIWLVTELASVGTLADLMSADGPVPLE--SIPSFVSDILS-GLNHAHLMGVVIRDL
.. ||| .|... | | . ... ||.|. . |.| | .. ..    |   | ..   .|. ||.. |  ... |||
MRQLDHPNIIKLYEVYEDENNYYLVMEYCEGGELYDKIKQCKRFFEEIQEICDIMQQLLWQGLHYMHQRNIMHRDL

Kinase AqueK214.AA Ciliate-E2a 251-276 53 5.6e-08 19.6 In-house 198-223 (275) Show / Hide
Range on Protein: 251-276
Range on HMM: 198-223/275
Sequence Identity: 53% (14 aa)

DLWSIGVIMYELWTGKCPFSGDTHTD
|.||.|||.| | .|| || | |...
DMWSCGVIFYILLCGKPPFKGKTYNE

Kinase AqueK214.AA CAMK 250-335 18 4.8e-07 17.99 In-house 315-413 (425) Show / Hide
Range on Protein: 250-335
Range on HMM: 315-413/425
Sequence Identity: 18% (21 aa)

TDLWSIGVIMYELWTGKCPFSGD-------------THTDLVHSIISYEPV-EIKEWRE----SNSTSNTSSSNSTGLEDHLLCVSYQ--------VMKL
.| ||.|||.| . .|. || ||             .  .| . |.. .   . ... .    .              ..   ..| .        .. |
CDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNY-------------GPEWWDDISDEFHHFVSQECKDL

MCGLLVKDPSKR
 ...|..||.||
IRKMLQVDPEKR

Kinase AqueK214.AA Ciliate-E2 48-152 19 7.8e-07 19.47 In-house 84-212 (365) Show / Hide
Range on Protein: 48-152
Range on HMM: 84-212/365
Sequence Identity: 19% (26 aa)

NQLSHLDHTHILQFLEWYR--SPQHIWLVTELASVGTLADLMS------------ADGPVPLESIPSFVSDILS---------------GLNHAHLMG-V
| |..|.| .|... |..   . ..| ||.|... |.| |..             . ..  .. |  .   ||.               .|.. |  . .
NILEQLNHPNIIKMYECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNI

VIRDLCPAKIYLDACGNLKLSDFSLAIDLKKNKDD
. ||. |  | .     .|..|| |. ..... ..
IHRDIKPENILF-----IKIIDFGLSKKYDDDNQN

TyrKc AqueK214.AA TyrKc 4-347 14 9.9e-07 -113.83 SMART 1-280 (280) Show / Hide
Range on Protein: 4-347
Range on HMM: 1-280/280
Sequence Identity: 14% (53 aa)

YVLYGEISSKPWCTVFKGRRKRTVEYV---SIHKYSTELYETLSHNVNQLSHL--DHTHILQFLEWYRSP-------QHIWLVTELASVGTLADLMSADG
 .|  .. .   ..|.||. |   . |   ......    | . .  . ...|  .| .|....   ...       . ...|.|... | | |   . .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR

P-VPLESIPSFVSDILSGLNHAHLMGVVIRDLCPAKIYLDACGNLKLSDFSLAIDLKKN-KDDDDNINVMKDIEQFYSSIININEKLLVQNNDADSTKSV
| ....   ||  .| .| .. | .... |||    . ... .  | ||| |. |..   .                                       
PKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQG-------------------------------------

DIPGVNSLTQQHSIQPPSNHKD---SAH--SPLLALNAHHFSSPSLPSPFYLSPESIEHSLFSIGTDLWSIGVIMYELWT-GKCPFSG-----DTHTDLV
                   .|    ...   |.                  ..||.| .. |.. .| || || |.|. | |. | .|      . ....
-------------ESKDYYRKKEHKGGKTMLPI----------------RWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVI

HSIISY---EPVEI----KEWRESNSTSNTSSSNSTGLEDHLLCVSYQVMKLMCGLLVKDPSKRHGWNDVIPIEGL
. . .    .. .                              | .  . ..|      ||..|   ...  .| .
EYVKQGYRMPQPPNDYPMS----------------------FVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF

Kinase AqueK214.AA NuaK 251-281 41 6e-06 11.14 In-house 181-211 (252) Show / Hide
Range on Protein: 251-281
Range on HMM: 181-211/252
Sequence Identity: 41% (13 aa)

DLWSIGVIMYELWTGKCPFSGDTHTDLVHSI
| || ||..| .  |  || |. .  ||  |
DCWSLGVLLYTMVYGTMPFDGHDFKHLVKQI

Kinase AqueK214.AA Pkinase_Tyr 236-271 39 4.4e-05 17.83 Pfam 181-218 (270) Show / Hide
Range on Protein: 236-271
Range on HMM: 181-218/270
Sequence Identity: 39% (15 aa)

LSPESIEHSLFSIGTDLWSIGVIMYELWT-GKCP-FSG
..||.| .. |.. .| || || |.|. | |. | . |
MAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPG

Kinase AqueK214.AA GIN4 232-272 38 0.000178 9.74 In-house 197-238 (293) Show / Hide
Range on Protein: 232-272
Range on HMM: 197-238/293
Sequence Identity: 38% (16 aa)

SPFYLSPESIEHSLFSIGT-DLWSIGVIMYELWTGKCPFSGD
|| | .|| .    .  .  | || |||.. | ||. ||  .
SPHYAAPEIVMGIPYHGFASDVWSCGVILFALLTGHLPFDEE

Kinase AqueK214.AA Ciliate-E2a 313-335 39 0.132499 0.52 In-house 241-263 (275) Show / Hide
Range on Protein: 313-335
Range on HMM: 241-263/275
Sequence Identity: 39% (9 aa)

LLCVSYQVMKLMCGLLVKDPSKR
....| . . || ..|.|||.||
WEKCSKECKDLMKKMLEKDPKKR