Gene AqueK220 (A.queenslandica)

AqueK220

Species: A.queenslandica
Alias: AqueK220
External Links:
Annotation:

Classification

Group: RGC
Family: RGC

Sequence

Name Sequence Type Origin Length Description Download
AqueK220.AA Protein None 1059 None Fasta, JSON
AqueK220.kin_dom Protein Kinase Domain None 96 None Fasta, JSON

Protein domain

Protein domains of AqueK220.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase AqueK220.AA RGC 577-696 31 1.4e-29 101.18 In-house 1-130 (300) Show / Hide 
Range on Protein: 577-696
Range on HMM: 1-130/300
Sequence Identity: 31% (41 aa)

AGNAVYIHKAKLNM--SQLNV--KMRQKILTILDFKHDNICPFVGGILQGSLITG-----LMYEYCTRGSLYDLLTNPHIGFNKSFRQSFAIDCSEGLAY
 |. | |.| . ..   ...   .|....    . .|||...|.| .. .  ...     .. |||.|||| |.| |  |.   .|. ||  |  .|. |
EGDWVWIKKHNQRNLFRHWDFTRSMMRELKQMRQLQHDNLNKFIGMCIDPPMEYHPGNMCIVWEYCSRGSLQDILENDDIKMDWMFKYSFIRDIVKGMQY

LHG-RKAIHGRLTSNNCVIDQHWNLKLTDY
||      ||.|.| |||.| .| .|.||.
LHHSPIRYHGNLKSWNCVVDSRWVVKITDF
Kinase AqueK220.AA RGC 577-696 31 1.9e-29 101.18 In-house 1-130 (300) Show / Hide 
Range on Protein: 577-696
Range on HMM: 1-130/300
Sequence Identity: 31% (41 aa)

AGNAVYIHKAKLNM--SQLNV--KMRQKILTILDFKHDNICPFVGGILQGSLITG-----LMYEYCTRGSLYDLLTNPHIGFNKSFRQSFAIDCSEGLAY
 |. | |.| . ..   ...   .|....    . .|||...|.| .. .  ...     .. |||.|||| |.| |  |.   .|. ||  |  .|. |
EGDWVWIKKHNQRNLFRHWDFTRSMMRELKQMRQLQHDNLNKFIGMCIDPPMEYHPGNMCIVWEYCSRGSLQDILENDDIKMDWMFKYSFIRDIVKGMQY

LHG-RKAIHGRLTSNNCVIDQHWNLKLTDY
||      ||.|.| |||.| .| .|.||.
LHHSPIRYHGNLKSWNCVVDSRWVVKITDF
Kinase AqueK220.AA TKL-Unique 607-697 28 2.7e-16 54.14 In-house 52-162 (290) Show / Hide 
Range on Protein: 607-697
Range on HMM: 52-162/290
Sequence Identity: 28% (33 aa)

FK-HDNICPFVGGIL-------QGSLITGLMYEYCTRGSLYDLLT---------NPHIGFNKSFRQSFAIDCSEGLAYLHGRK--AIHGRLTSNNCVIDQ
.. |.||  ..|.         . ....    ||| .|||||.|.         |... .| . | ..|||.. |. ||| ..   ||. |.| |  .|.
LHYHPNIVHYMGYCMDHQVYPPNMCIVM----EYCPGGSLYDVLHQNNNNNNNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDN

H-----WNLKLTDYE
.     || |. | .
NSNIAEWNIKICDFG
Kinase AqueK220.AA TKL 598-696 21 6.6e-16 53.76 In-house 73-198 (364) Show / Hide 
Range on Protein: 598-696
Range on HMM: 73-198/364
Sequence Identity: 21% (29 aa)

RQKILTILDFKHDNICPFVGGILQGSL------------ITGLMYEYCTRGSLYDLLTNPHIGFNKSFRQSFAIDCSEGLAYLHGRK--------AIHGR
.. |. .. ..|.||..|.|  ....               .. .||| .|||...|.        . | ..|.|.. |..||| ..         ||  
EEEIMMMSRLRHPNIVQFMGYCCCPPCGCVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRD

LTSNNCVIDQHWN--------------LKLTDY
|.|.|. .|..|.              .|..|.
LKSKNILVDENWTNVSNYMYNPNADWCCKICDF
Kinase AqueK220.AA MLK 607-695 27 2.6e-12 39.16 In-house 62-176 (291) Show / Hide 
Range on Protein: 607-695
Range on HMM: 62-176/291
Sequence Identity: 27% (32 aa)

FKHDN----ICPFVGGILQGSLITGLMYEYCTRGSLYDLL----TNPH---------IGFNKSFRQSFAIDCSEGLAYLHGRKA---IHGRLTSNNCVID
..| |    |..|.|..||     ..  |||  ||||..|    ...          .    ..  ..| .|..|..|||  .    ||  | | | .||
LSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNVLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILID

Q------HWNLKLTD
.      | .|| .|
EICHDMHHGTLKICD
Kinase AqueK220.AA DRK 609-696 36 5.4e-12 36.95 In-house 56-144 (258) Show / Hide 
Range on Protein: 609-696
Range on HMM: 56-144/258
Sequence Identity: 36% (33 aa)

HDNICPFVGGILQGSLITGLMYEYCTRGSLYDLLTNPHIGFNKSFRQSFAIDCSEGLAYLHGRK--AIHGRLTSNNCVIDQHWNLKLTDY
| ||| | |  .  . |   | ||  |||||  | .. |    . . . ..||  |. |||..    ||  | | |  .| ||  |  |.
HPNICQFMGTCNNPPDICICM-EYMPRGSLYNILHDESIEMDWPLMKQMMFDCAKGMIYLHCCNPIIIHRDLKSHNLLVDEHWQVKVADF
Kinase AqueK220.AA TK 580-696 12 1.6e-08 23.91 In-house 56-295 (486) Show / Hide 
Range on Protein: 580-696
Range on HMM: 56-295/486
Sequence Identity: 12% (30 aa)

AVYIHKAKLNMSQLNVKM--------------RQKILTILD---FKHDNICPFVGGILQGS-----------LITGLMYEYCTRGS----LYDLLTNPHI
|| . |.. .|||   ..                 .. ...   ..|.||  ..| ..||                .. ||.  |.    | | | . . 
AVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLGHHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRP

GFNK---------------------------SFRQS-----------------------------------------------FAIDCSEGLAYLHGRKA
.|..                           |....                                               .. . ..|..||| .. 
KFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDYDDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNC

------IHGRLTSNNCVIDQHWN-----------LKLTDY
      .|. |   || .... .            |..|.
EFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADF
Kinase AqueK220.AA Dicty5 631-696 32 2.1e-08 25.0 In-house 79-148 (260) Show / Hide 
Range on Protein: 631-696
Range on HMM: 79-148/260
Sequence Identity: 32% (23 aa)

EYCTRGSLYDLLTNPHI--GFNKSFRQ--SFAIDCSEGLAYLHGRKAIHGRLTSNNCVIDQHWNLKLTDY
||| .||| ..|       | . .. |  ..|||   .. .||    ||  | |.|  |   |  |. |.
EYCHNGSLFNYLNDQRKTTGQPIAYFQQLHMAIDIAQSMRHLHSMNIIHRDLKSMNFLITENWKIKIIDF
Kinase AqueK220.AA TESK 631-685 32 2.9e-08 21.71 In-house 73-127 (292) Show / Hide 
Range on Protein: 631-685
Range on HMM: 73-127/292
Sequence Identity: 32% (18 aa)

EYCTRGSLYDLLTNPHIGFNKSFRQSFAIDCSEGLAYLHGRKAIHGRLTSNNCVI
||   |.| .|| .  .      .   |.|   |. ||| .   |  ||| || .
EYINGGCLEQLLADSELHLSWTQKIHLAYDIARGMSYLHSKGVFHRDLTSKNCLV
S_TKc AqueK220.AA S_TKc 565-793 16 1.1e-07 -64.4 SMART 1-231 (231) Show / Hide 
Range on Protein: 565-793
Range on HMM: 1-231/231
Sequence Identity: 16% (43 aa)

YNGDQTIGQINNAGNAVYIHKA--------KLNMSQLNVKMRQKILTILDFKHDNICPFVGGILQGSLITGLMYEYCTR--GSLYDLLTNPHIG-----F
|   ..||.   .     .||         ...      ..|. |      .|.||. . . .        .  |||    |.|.|.. .   .     |
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----EHIRREIQILKK-HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF

NKSFRQSFAIDCSEGLAYLHGRKAIHGRLTSNNCVIDQHWNLKLTD-----YEPIDIHYTKVKRLSKLKTAAKKIYYLP----DQDT-VSDIYNFGVILT
.    ....    ..|.|.| .. ||  |   |  .|.  ..|..|                      .|     .|..      ..  .|.. .|.|| 
PE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---------------TTFCGTPWYMAPEVLGYGKCKCDWWSCGCILY

ELCCRETLLKFGSINFGKIHYDEDVGDRYVELIEKCHQMKKSARPSASFIKG---------YL
|..|....         |.       .   ..|.|| |.  . ||.|  .           ..
EMLCGYPPFP-QMQMMFKKIG----SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK220.AA TyrKc 583-793 16 2.7e-07 -104.67 SMART 15-280 (280) Show / Hide 
Range on Protein: 583-793
Range on HMM: 15-280/280
Sequence Identity: 16% (45 aa)

IHKAKLNMSQLNV-----------KMRQKILTILDF--KHDNICPFVGGILQG-------SLITGLMYEYCTRGSLYDLLTNPHIGFNKSFRQSFAIDCS
..|....   ..|            ... .     .  .|.||  ..| ..|.         .  .| ||.  |.| | | ...  .. .   ||... .
VYKGTWK---IQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVM-EYMPHGDLKDYLRKHRPKLCMKDLLSFCWQIA

EGLAYLHGRKAIHGRLTSNNCVIDQHWNLKLTDY---EPIDIH--------YTKVKRLSKLK-----------TAAKKIYYLPDQDTVSDIYNFGVILTE
.| .||| .. ||  |   || ..     | .|      |. .        | ..|  .  |           .  ....      | ||.. ||| . |
CGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT-----TKSDVWSFGVCMWE

LCCRETLLKFG---------------SINFGKIHYDE--------DVGDRYVELIEKCHQMKKSARPSASFIKGYL
.. .      |                  .     ..           . |  ....| . . . ||. | |. ..
IFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQ-IMKQCWHEDPEDRPTFSEIHECF
Kinase AqueK220.AA TKL 729-793 15 3.1e-05 14.8 In-house 270-364 (364) Show / Hide 
Range on Protein: 729-793
Range on HMM: 270-364/364
Sequence Identity: 15% (15 aa)

SDIYNFGVILTELCCRETLLK-FG-----------SINFGKIHYD------------------EDVGDRYVELIEKCHQMKKSARPSASFIKGYL
.|.| ||..| |...|..  . ..            .  . ..                    .|. ... .|...| ... ..|||.. |. .|
CDVYSFGIVLWEILTRCRPYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase AqueK220.AA LRRK 631-682 29 0.000169 11.81 In-house 135-196 (351) Show / Hide 
Range on Protein: 631-682
Range on HMM: 135-196/351
Sequence Identity: 29% (18 aa)

EYCTRGSLYDLLTNPH-IG-------FNKSFRQSFAIDCSEGLAYLHGRK--AIHGRLTSNN
|| . |.||..| |..  |       .. ....  |.. ..|..||| ..   ||  |.| |
EYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNPPIIHRDLKSPN
Kinase AqueK220.AA LRRK 767-795 34 0.000408 10.44 In-house 323-351 (351) Show / Hide 
Range on Protein: 767-795
Range on HMM: 323-351/351
Sequence Identity: 34% (10 aa)

RYVELIEKCHQMKKSARPSASFIKGYLKD
.| .||..| | .   ||..| |   |..
MYQDLIQHCWQHDPKKRPHFSQIVKRLSQ
Kinase AqueK220.AA Dicty5 763-797 34 0.093845 1.81 In-house 226-260 (260) Show / Hide 
Range on Protein: 763-797
Range on HMM: 226-260/260
Sequence Identity: 34% (12 aa)

DVGDRYVELIEKCHQMKKSARPSASFIKGYLKDCL
|.   .  ||.|| | | . |||   |  |..   
DCPTEISNLIKKCWQQKPHNRPSFKEICKYFESII