Gene AqueK227 (A.queenslandica)

AqueK227

Species: A.queenslandica
Alias: AqueK227
External Links:
Annotation:

Classification

Group: STE
Family: STE11
Subfamily: MEKK2

Sequence

Name Sequence Type Origin Length Description Download
AqueK227.AA Protein None 597 None Fasta, JSON
AqueK227.kin_dom Protein Kinase Domain None 266 None Fasta, JSON

Protein domain

Protein domains of AqueK227.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase AqueK227.AA STE11 326-591 40 4.1e-127 428.6 In-house 1-303 (303) Show / Hide 
Range on Protein: 326-591
Range on HMM: 1-303/303
Sequence Identity: 40% (126 aa)

WSKGRLLGTGAFGQVFLCTDLDTQMDMAVKVVDIDHIENIKPSLDSLKMSKEVRS------FETEVQLLKNIHHERVVGYYGTERR---EGKLFIFMEYL
| || ..|.||||.|..| ..||.  |||| . |. ... |      . .||..|      .. |..|.|...|.. | |||....   .... ||||| 
WQKGEIIGKGAFGTVYKCMNVDTGELMAVKQIEIQNNNQMK-----EDQEKEYQSHKMHKAIQEEIKLMKHLNHKNIVRYYGCCLHDNQNDHVNIFMEYC

AGGSIYQHLK-NTGA--LSEALTRKYTRQILEGVAFLHGMKIVHRDIKGANILRDSNGN-VKLADFGASKRLQTIRSGIGS----------VHGTPY---
.|||. . |. . |.  ..|...||||.|||||...||  .|.||||||||||.||.|| .||||||..|||..| .   .          . ||||   
PGGSLSSMLRHKWGPMKFDEMVIRKYTKQILEGLQYLHSHGIIHRDIKGANILLDSDGNVCKLADFGCAKRLAWICTCTHNMNMTQNHCKSMTGTPYNSM

-----WMAPEVIKGDDP--YTFKADIWSVGATVVEMLKCRPPWSDFE--PTAAMFKIVMN-DTKPDLPPHCS------EQAHNFIELCFIKDKNERPSAM
     ||||||||.     |. ||||||.|.||.||.  .|||....  . ||||||.|. .. | .| | |      |....|. .|| .|...||.|.
MGTPMWMAPEVIKQEGRDGYGRKADIWSLGCTVIEMATGKPPWHNYDHNHMAAMFKIGMGHKPHPPIPEHMSPISWISEECRDFLRHCFEHDPKKRPTAN

DLLSHSFC
.|| |.|.
QLLQHPFI
Kinase AqueK227.AA MEKK2 326-591 56 1.7e-126 426.56 In-house 1-262 (262) Show / Hide 
Range on Protein: 326-591
Range on HMM: 1-262/262
Sequence Identity: 56% (152 aa)

WSKGRLLGTGAFGQVFLCTDLDTQMDMAVKVVDIDHIENIKPSLDSLKMSKEVRSFETEVQLLKNIHHERVVGYYGTERREG--KLFIFMEYLAGGSIYQ
| .|.||| ||||.|..| | ||  ..||| |..|         |.   .|||.. | |.|||||. |||.| |||  | ..   | |||||..|||.  
WRRGKLLGQGAFGRVYVCYDVDTGRELAVKQVQFDP--------DNPETRKEVQALECEIQLLKNLQHERIVQYYGCLRDNQEKTLSIFMEYMPGGSVKD

HLKNTGALSEALTRKYTRQILEGVAFLHGMKIVHRDIKGANILRDSNGNVKLADFGASKRLQTIRS---GIGSVHGTPYWMAPEVIKGDDPYTFKADIWS
.||  ||| |. |||||||||||...||   ||||||||||||||| |||||.||||||||||| .   |. || ||||||.|||| |.  |  |||.||
QLKAYGALTETVTRKYTRQILEGMHYLHDHMIVHRDIKGANILRDSSGNVKLGDFGASKRLQTICMHITGMKSVTGTPYWMSPEVINGEG-YGRKADVWS

VGATVVEMLKCRPPWSDFEPTAAMFKIVMNDTKPDLPPHCSEQAHNFIELCFIKDKNERPSAMDLLSHSFC
.| ||||||  .||| ..|  ||.|||   .|.| ||.| |..| .|...||.. | .|||| .|| | | 
IGCTVVEMLTEKPPWAEYEAMAAIFKIATQPTNPQLPQHVSQHARDFLKRCFVEIKQDRPSAEELLRHHFV
Kinase AqueK227.AA STE11-Unclassified 326-591 38 2.6e-107 362.83 In-house 1-308 (308) Show / Hide 
Range on Protein: 326-591
Range on HMM: 1-308/308
Sequence Identity: 38% (120 aa)

WSKGRLLGTGAFGQVFLCTDLDTQMDMAVKVVDIDHIENIKPSLDSLKMSKE-VRSFETEVQLLKNIHHERVVGYYGTE--RREGKLFIFMEYLAGGSIY
| || ..|.|.||||..| ...|   |||| . |  .          .| || . |.. |...||. .|.  | |||.|  . |... ||||| .|||| 
WQKGEFIGKGSFGQVYKCMNCNTGEFMAVKQIEIHDYNS-----QQEDMQKEMIQSIQKEMKVLKQLNHKNIVQYYGCEIHKHEDCINIFMEYMPGGSIW

QHLKNTGALSEALTRKYTRQILEGVAFLHGMKIVHRDIKGANILRDSNGNVKLADFGASKRLQ------------------TIRSGI-------GSVHGT
. |.. |...|....|||.|||||.|.||  .|.|||||||||| |..|..||.|||..|                     .| . |        |  ||
SMLNKYGCFDEMVIKKYTKQILEGLAYLHSHGIIHRDIKGANILIDFDGICKLTDFGCAKQIEFDRTRTVRMNKIQNFDHYKICQHINSQQNHCKSMQGT

PY---WMAPEVIKG--DDPYTFKADIWSVGATVVEMLKCRPPWSDFEP---TAAMFKIVMNDTKPDLPPHCS-----------EQAHNFIELCFIKDKNE
||   ||||||||.   . .. |.||||.| ||.||   ..|||....   ..|..|||| .. | .| | |           ... .|...||  |...
PYQPFWMAPEVIKNSTQTGHCRKSDIWSLGCTVIEMATGKHPWSNCQNDNFMWAIMKIVMSNQIPQIPEHLSPVCDFISCWISQECKDFLRKCFQIDPKK

RPSAMDLLSHSFC
||.|  ||.|.| 
RPTANQLLQHPFI
Kinase AqueK227.AA STE 326-591 29 7.29999999999e-106 358.0 In-house 1-359 (359) Show / Hide 
Range on Protein: 326-591
Range on HMM: 1-359/359
Sequence Identity: 29% (107 aa)

WSKGRLLGTGAFGQVFLCTDLD---------------TQMDMAVKVVDIDHI-------ENIKPSLDSLKMSKEVRSFETEVQLLKNIH--HERVVGYYG
| . . .| ||||.|... . .               |.  ||.|......        || . . .. | ..|. ... |....|. .  |. .| |||
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQEN-Q-E-LENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYG

TERREG-------KLFIFMEYLAGGSIYQHLKNT--------------GALSEALTRKYTRQILEG-VAFLHGMKIVHRDIKGANILRDSNGNVKLADFG
.. .||       .|.|.|||..|||. . .|..              . ..| . ....||||.|  ..|| ..|.|||||.||||      |||.|||
CYFKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFG

ASKRLQTIRSGI------------G----SVHGTPYWMAPEVIKG-----DDPYTFKADIWSVGATVVEMLKCRPPWSDFEPTAAMFKIVMN--------
 ...|. . ..|            .    .. ||| |||||||..     |..|..|.||||.| |..||.  .|||.|. |. ||| | .|        
VCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFE

------DTKPDLPP-------------------HCSEQAHNFIELCFIKDKNERPSAMDLLS--HSFC
      .. | ||.                   ..|.  ..||..|..|| |.||.| .||.  |.| 
QLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase AqueK227.AA S_TKc 326-591 28 2.3e-94 320.74 SMART 1-231 (231) Show / Hide 
Range on Protein: 326-591
Range on HMM: 1-231/231
Sequence Identity: 28% (81 aa)

WSKGRLLGTGAFGQVFLCTDLDTQMDMAVKVVDIDHIENIKPSLDSLKMSKEVRSFETEVQLLKNIHHERVVGYYGTERREGKLFIFMEYLAG--GSIYQ
. ..|..| ||||.|..|.. .|.  .|.|...                    .... |.|.||. ||. .| .|.. .  ..|...|||. |  |. ..
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------------------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFD

HLKNTGA------LSEALTRKYTRQILEGVAFLHGMKIVHRDIKGANILRDSNGNVKLADFGASKRLQTIRSGIGSVHGTPYWMAPEVIKGDDPYTF-KA
..|. |       ..|  .|.|..||.......| ..|.|||.| .||| |.  ..|..||| ...|        .. |||..|||||.    .|.. |.
YIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL----GYGKCKC

DIWSVGATVVEMLKCRPPWSDFEPTAAMFKIVMNDTKPDLPPHCSEQAHNFIELCFIKDKNERPSAMDLLS-------HSFC
|.||.| .. |||  .||..     ..|||...           |..| .||. |. || ..||.| ..|        | . 
DWWSCGCILYEMLCGYPPFP---QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK227.AA MEKK15 326-591 42 9.4e-87 294.52 In-house 1-264 (264) Show / Hide 
Range on Protein: 326-591
Range on HMM: 1-264/264
Sequence Identity: 42% (116 aa)

WSKGRLLGTGAFGQVFLCTDLDTQMDMAVKVVDIDHIENIKPSLDSLKMSKEVRSFETEVQLLKNIHHERVVGYYGTERREGKLFIFMEYLAGGSIYQHL
| || .|| ||.| |.       |. .||| |..| |       | .|  .. |    ||.||| ..|  .|.| |.   .  . |||... ||||   .
WKKGNILGKGAYGTVYCGLTNTGQL-IAVKQVELDEI-------DKEKAKQQYRKLQEEVDLLKTLKHKNIVAYLGVCLEDNVVNIFMQFVPGGSISSII

KNTGALSEALTRKYTRQILEGVAFLHGMKIVHRDIKGANILRDSNGNVKLADFGASKRLQTI---RSG---IGSVHGTPYWMAPEVIKGDDPYTFKADIW
   |.| |    |||.|||.||..||   .|||||||.|..  . | .|| |||  |||      |.    . |..|||||||||||. .  |  |.|||
NRFGPLDEMVFCKYTKQILQGVQYLHENCVVHRDIKGNNVMLMPTGIIKLIDFGCAKRLCWQGINRTHSDMLKSMRGTPYWMAPEVIM-ETGYGRKSDIW

SVGATVVEMLKCRPPWSDFEPTAAMFKIVMN-DTKPDLPPHCSEQAHNFIELCFIKDKNERPSAMDLLSHSFC
|.| || ||   .||| | .. |||| |    |  |.|| . ||.| .|...|  .|..|||.|..|| |.| 
SIGCTVFEMATRKPPWADMDRMAAMFYIGAHRDPMPQLPVKFSEDARMFVRMCLTRDQHERPTASQLLKHPFI
Kinase AqueK227.AA Pkinase 326-591 29 2.4e-79 274.73 Pfam 1-293 (293) Show / Hide 
Range on Protein: 326-591
Range on HMM: 1-293/293
Sequence Identity: 29% (91 aa)

WSKGRLLGTGAFGQVFLCTDLDTQMDMAVKVVDIDHIENIKPS----LDSLKMSKEVRSFETEVQLLKNIHHERVVGYYGTERREGKLFIFMEYLAGG--
. .|| .| |.||.|..|.. .|.   |||... .|..  |.     |             .|.|..|...|. .| .|.. ...... . |||. ||  
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRL-------------SEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLY

--SIYQHLK--NTGAL--SEALTRKYTRQILEGVAFLHGMKIVHRDIKGANILRDSNGNV----KLADFGASKRL-QTIRSGIGSVHGTPYWMAPEVIKG
  . . ...  . |..  ||   ..| .|||.|....| |.|.|||.| .||| |.||..    |..||| .| .     |   .. |||..||||||.|
VMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRG

DDPYTFKADIWSVGATVVEMLKCRPPWSDF------EPTAAMFKIVMNDTKPDLPPHCS-------------------EQAHNFIELCFIKDKNERPSAM
. .|. |.|.||.| .. |||  |||...       .. . ...| . ... | |  ||                   | .  ||. |. || ..||.|.
GQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAE

DLLSHSFC
..| | . 
QILQHPWF
Kinase AqueK227.AA STE20 326-591 31 1e-78 267.83 In-house 1-288 (288) Show / Hide 
Range on Protein: 326-591
Range on HMM: 1-288/288
Sequence Identity: 31% (95 aa)

WSKGRLLGTGAFGQVFLCTDLDTQMD----MAVKVVDIDHIENIKPSLDSLKMSKEVRSFETEVQLLKNIHHERVVGYYGTERRE----GKLFIFMEYLA
. . . .| |..|.|..... .|.       |.|...... .|           .|... ..|.. .|. .|. .| |||.  ..     .|.| |||..
YELLEKIGQGSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNE--------Q-DEWEDIQKEISIMKQCKHPNIVKYYGSYLKDDTCDDELWIVMEYCG

GGSIYQHLK---NTG------ALSEALTRKYTRQILEGVAFLHGMKIVHRDIKGANILRDSNGNVKLADFGASKRLQT-----IRSGIGSVHGTPYWMAP
|||. . .|   ..|       ..|.     .|..|.| ..|| ..|.|||||..||| ...|.||||||| .  |..     ...   .. ||||||||
GGSLTDIMKHCMKCGKNHKGHPMNEEQIAYICREVLQGLDYLHSNHIIHRDIKADNILLTEDGEVKLADFGVCAQLTKHGRDTMQFKRNTFVGTPYWMAP

EVIKG----DDPYTFKADIWSVGATVVEMLKCRPPWSDFEPTAAMFKIV--MNDTKPDL---PPHCSEQAHNFIELCFIKDKNERPSAMDLLSHSFC
|||..    | .|..|.||||.| |  ||.. .|| .|. |. |||.|    |.. ..    | ..| . |.|...|  || ..||.| .||.|.| 
EVIQCMEGPDKGYDYKCDIWSLGITAIEMAEGEPPYFDMHPMRAMFMIPKNQNPPPTLKDDKPHKWSPEFHDFVDKCLQKDPEKRPTASQLLKHPFI
Kinase AqueK227.AA YSK 326-591 37 5.6e-75 225.1 In-house 1-257 (257) Show / Hide 
Range on Protein: 326-591
Range on HMM: 1-257/257
Sequence Identity: 37% (102 aa)

WSKGRLLGTGAFGQVFLCTDLDTQMDMAVKVVDIDHIENIKPSLDSLKMSKEVRSFETEVQLLKNIHHERVVGYYGTERREGKLFIFMEYLAGGSIYQHL
..|    | | || |.   |  ||   |.|..| .| |             |.     |.| |       .  |||.  .  || | |||..|||. . .
FTKQECIGRGSFGEVYKGIDNRTQRVVAIKIIDLEHAED------------EIEDIQQEIQFLSQCDSPYITKYYGSYLKDTKLWIIMEYCGGGSCLDLM

KNT--GALSEALTRKYTRQILEGVAFLHGMKIVHRDIKGANILRDSNGNVKLADFGASKRLQTIRSGIGSVHGTPYWMAPEVIKGD-DPYTFKADIWSVG
|    |.. |       | || |  .||  . .||||| ||.|   .|.|||.||| . ..           |||||||||||. . . | |||||||.|
KPKYVGQFDEKYIAIILREILKGLDYLHSERKIHRDIKAANVLLSEHGDVKLCDFGVAGQITDTQIKRNTFVGTPYWMAPEVICQEVSYYDFKADIWSLG

ATVVEMLKCRPPWSDFEPTAAMFKIVMNDTKPDLPP-HCSEQAHNFIELCFIKDKNERPSAMDLLSHSFC
 |  ||.|  || .| .|  .|| |. |   | |   . |  . .|.|.|  || ..|||| .||.|.| 
ITAYEMAKGEPPYCDYHPMRVMFLIPKNNP-PKLEGRSYSKMFKEFVECCLNKDPEQRPSAKELLKHKFI
Kinase AqueK227.AA CAMK 331-591 18 5.6e-70 224.45 In-house 1-425 (425) Show / Hide 
Range on Protein: 331-591
Range on HMM: 1-425/425
Sequence Identity: 18% (78 aa)

LLGTGAFGQVFLCTDLDTQ------------MDMAVKVVDIDHIENIKPSLDSLK-----------------MSKEVRSFETEVQLLKN-------IHHE
 ||.|.||.|.||..  |.               |.|..| . . . ..  |.                     |  .... |....|.       ..|.
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQN-QDY-SNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHP

RVVGYYG---------------TERR-----EGKLFIFM---EYLAGG----SIYQHLKNT---------------GALSEALTRKYTRQILEGVAFLHG
 ..  |                | ..     . .....|   ||  ||     ......                 | ..|. .|.| |||...|...| 
NIIKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHS

MKIVHRDIKGANILRDSN-----------------GNVKLADFGASKRLQTIRSG-----------------------IGSVHGTPYWMA-PEVIKG---
..|||||.|  ||| |.|                 .|.|..||| .....   .                           . |||. || |||..|   
HNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGH

----------DDPYTFKADIWSVGATVVEMLKCRPPWSDFEPT------------AAMFKIVMNDTKPDLPPH-----------------------CSEQ
           ..|..|.|.||.|     ||  .||. .                  .|. .|.      ||.                       .|..
CNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQE

AHNFIELCFIKDKNERPSAMDLLSHSFC
. ..|  .  .| ..|... . |.| . 
CKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase AqueK227.AA ASK 331-591 38 1.1e-68 227.52 In-house 1-254 (254) Show / Hide 
Range on Protein: 331-591
Range on HMM: 1-254/254
Sequence Identity: 38% (104 aa)

LLGTGAFGQVFLCTDLDTQMDMAVKVVDIDHIENIKPSLDSLKMSKEVRSFETEVQLLKNIHHERVVGYYGTERREGKLFIFMEYLAGGSIYQHLKNT-G
 || |..| |.   |..||. .|.| ..  . .             .|.    |..| |...|. .| | |.  ..| . ||||   |||. . |.   |
VLGKGTYGIVYAGRDMHTQVRIAIKEIPERDSR-------------YVQPLHEEIALHKQLRHRNIVQYLGCCSENGYFKIFMEQVPGGSLSALLRSKWG

ALS--EALTRKYTRQILEGVAFLHGMKIVHRDIKGANILRDS-NGNVKLADFGASKRLQTIRSGIGSVHGTPYWMAPEVI-KGDDPYTFKADIWSVGATV
 .   |   . ||.|||||. .||  .|||||||| |.|     | ||..||| .|||  |     .  ||  .|||||| .|   |   |||||.| |.
PMKDNENTMNFYTKQILEGLKYLHENQIVHRDIKGDNVLVNTYSGVVKISDFGTCKRLAGINPCTETFTGTLQYMAPEVIDQGQRGYGKPADIWSFGCTM

VEMLKCRPPWSDF-EPTAAMFKIVMNDTKPDLPPHCSEQAHNFIELCFIKDKNERPSAMDLLSHSFC
|||   .||. .. || |||||. |  . |..|   |....|||  ||  | ..|.|| |||   | 
VEMATGKPPFHELGEPQAAMFKVGMYKKHPEIPEELSAECKNFILRCFEPDPCKRASAQDLLQDPFL
Kinase AqueK227.AA Dicty2 383-591 39 1.5e-63 217.41 In-house 52-264 (264) Show / Hide 
Range on Protein: 383-591
Range on HMM: 52-264/264
Sequence Identity: 39% (85 aa)

TEVQLLKNIHHERVVGYYGTERREGKLFIFMEYLAGGSIYQHLKNTGALSEALTRKYTRQILEGVAFLHGMKIVHRDIKGANILRDSNGN---VKLADFG
.|. |||.  |.  | |.. .  |  | |..||  .|| .  .|. | ..| |   | .|.|.| . ||  ...|||||.||||   .|    .||||||
QEIHLLKKLNHHNIVKYIEHIETENHLYIILEYIENGSLSKIIKKFGCFPESLCCIYIYQVLKGLVYLHRQGVIHRDIKAANILITKEGKSGVIKLADFG

ASKRLQ--TIRSGIGSVHGTPYWMAPEVIKGDD-PYTFKADIWSVGATVVEMLKCRPPWSDFEPTAAMFKIVMNDTKPDLPPHCSEQAHNFIELCFIKDK
    .    . |   .| |||||||||||  ..   . . ||||.| |. |.|   || .|  | .|||..| .|  | ||.  | .  .| . || || 
VATHIDYSDDDSRY-TVVGTPYWMAPEVIQMSGNHCCTACDIWSLGCTIIELLTGNPPYWDLNPMHAMFRMVQDD-HPPLPNDISPECKDFLMQCFCKDP

NERPSAMDLLSHSFC
|.|..|  ||.|   
NQRMTAKQLLHHPWI
Kinase AqueK227.AA Pkinase_Tyr 326-588 23 7.8e-31 105.05 Pfam 1-269 (270) Show / Hide 
Range on Protein: 326-588
Range on HMM: 1-269/270
Sequence Identity: 23% (66 aa)

WSKGRLLGTGAFGQVFLCTDL----DTQMDMAVKVVDIDHIENIKPSLDSLKMSKE--VRSFETEVQLLKNI-HHERVVGYYGTER-REGK--LFIFMEY
 ..|. || ||||.|...|      .|... |||..                |...   ..|  |....|.. ||. .| .||    ...   ..| |||
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLK------------EGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEY

LAGGSIYQHLKN----TGALSEALTRKYTRQILEGVAFLHGMKIVHRDIKGANILRDSNGNVKLADFGASKRL-------QTIRSGIGSVHGTPYWMAPE
 ..|. . .|..     ..|.     .. .|| .| ..|. ....|||.   |.| ..|. || .||| .. .       ..  .|   .     |||||
MPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIK----WMAPE

VIKGDDPYTFKADIWSVGATVVEMLK-CRPP-WSDFEPTAAMFKIVMNDTKPDLPPHCSEQAHNFIELCFIKDKNERPSAMDLLSH
.|.    .| | |.|| | .  |..  .. | . .  ..  . .|  .    . |..|..  .. . .|  .| ..||.  .....
CINYGK-FTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQ
Kinase AqueK227.AA TyrKc 326-590 22 3.8e-23 84.12 SMART 1-280 (280) Show / Hide 
Range on Protein: 326-590
Range on HMM: 1-280/280
Sequence Identity: 22% (69 aa)

WSKGRLLGTGAFGQVFLCTDLDTQMDMAVKVVDIDHIENIKPSLDSLKMSKEVRSFETEVQLLKNI--HHERVVGYYGTERRE-------GKLFIFMEYL
 ..|. || ||||.|...|     .. |||..  |.                .. |  | ......  ||. .|  ||  . .       . |.| ||| 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA----------------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYM

AGGSIYQHLKNTGA-LSEALTRKYTRQILEGVAFLHGMKIVHRDIKGANILRDSNGNVKLADFGASKRLQTI-----RSGIGSVH---GTP-----YWMA
..|.  ..|....  |. .   ..  || .| ..|| ....|||.   |.| ..|. || .||| |. .        ..   ..    |.       |||
PHGDLKDYLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMA

PEVIKGDDPYTFKADIWSVGATVVEML-KCRPPWSD----FEPTAAMFKIVMNDTKPDLPPH--------CSEQAHNFIELCFIKDKNERPSAMDLLSHS
||.|  .  .|.| |.|| | .  |..  . .|...    . . . ... |..   .. ||.        |..  .. .. |   | ..||.  ..  . 
PECI-NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI-HEC

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