Gene AqueK252 (A.queenslandica)

AqueK252

Species: A.queenslandica
Alias: AqueK252
External Links:
Annotation:

Classification

Group: TK
Family: Csk

Sequence

Name Sequence Type Origin Length Description Download
AqueK252.AA Protein None 387 None Fasta, JSON
AqueK252.kin_dom Protein Kinase Domain None 248 None Fasta, JSON

Protein domain

Protein domains of AqueK252.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
SH2 AqueK252.AA SH2 48-123 40 1e-30 92.01 Pfam 1-81 (81) Show / Hide 
Range on Protein: 48-123
Range on HMM: 1-81/81
Sequence Identity: 40% (33 aa)

WFHGDITRADSEALLTP--PKDGLFLVRESQAHKGNYTLCVSYKG---KVEFYQIEKDSRQWVSADGEEYFENLVKLVEHY
|.||.|.|.. | ||    ..|| ||||||. ..| |||.| ..|   .|. |.| .. .  .   |...|..|  |||||
WYHGKISRQEAERLLMNPGNPDGTFLVRESESTPGDYTLSVRDDGPGDRVKHYRIQRTDNGGYYITGRHKFCSLQELVEHY
SH2 AqueK252.AA SH2 46-129 38 1.8e-30 108.49 SMART 1-87 (87) Show / Hide 
Range on Protein: 46-129
Range on HMM: 1-87/87
Sequence Identity: 38% (34 aa)

MPWFHGDITRADSEALLTP--PKDGLFLVRESQAHKGNYTLCVSYKGKVEFYQIEKDS-RQWVSAD-GEEYFENLVKLVEHYQKDADG
.||.||.|.|.. |.||    ..|| ||||.|. ..| |.|.| .||||  |.|...  .... .. ....|..|  ||.|||. ..|
QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSESNPGDYVLSVRWKGKVKHYRIRRNDDGKYYIDETWRRKFPSL-ELVNHYQHNPLG
TyrKc AqueK252.AA TyrKc 165-380 31 9.3e-91 308.74 SMART 1-280 (280) Show / Hide 
Range on Protein: 165-380
Range on HMM: 1-280/280
Sequence Identity: 31% (90 aa)

LDMKSTLGKGEFGEVWLGEYRGNKVAIKMLKEIKSRQATQQFLAEASVMTTL--SHTNLVGLIGVSLDE-------SPIYLVTEFMGKGALEQYLRTRGR
. .. .|| |.||||..|...  .||.||||| .     . |. ||..|. |  .| |.| |.|| ...        |...|.|.| .|.| .||| ...
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP

SVITKQNQIDFARNVCNGMVYLESKNFVHRDLASRNVLLSDEL--------------------------------VAK----------------KFSNKS
  .. .  ..|.  ...|| ||.|||..||||| ||.|.....                                 .|                ||. ||
K-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKS

DVWSFGIFLWELYSYGRVPYPR-----VPANDIMQFVERGYRMDPPDG--------CPPVIYQIMKDCWQADPNARPNFTRIMKSL
||||||. .||...||  |||      ... .....|..||||..|.         ||. .|||||.||..||. ||.|. | . .
DVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase AqueK252.AA Csk 165-301 54 4.7e-73 248.6 In-house 1-137 (251) Show / Hide 
Range on Protein: 165-301
Range on HMM: 1-137/251
Sequence Identity: 54% (75 aa)

LDMKSTLGKGEFGEVWLGEYRGNKVAIKMLKEIKSRQATQQFLAEASVMTTLSHTNLVGLIGVSLDES-PIYLVTEFMGKGALEQYLRTRGRSVITKQNQ
|.. .. |.|||| | .|||...|||.|..|.  .  . | |||||||||.|.| ||| |||| |..   .|.|.|.| || |  |||.|||.|||.. .
LHLGECIGHGEFGDVMQGEYQNRKVAVKCIKC-DGNGMAQAFLAEASVMTQLRHPNLVQLIGVILHQKNHLYIVMEYMSKGNLVDYLRSRGRHVITRRQL

IDFARNVCNGMVYLESKNFVHRDLASRNVLLSDELVAK
. ||  ||.|| |||.|.||||||| ||.|.|...|||
LKFAMDVCEGMCYLEQKKFVHRDLAARNILVSEDCVAK
Kinase AqueK252.AA Pkinase_Tyr 165-301 36 1.5e-61 209.12 Pfam 1-151 (270) Show / Hide 
Range on Protein: 165-301
Range on HMM: 1-151/270
Sequence Identity: 36% (56 aa)

LDMKSTLGKGEFGEVWLGEYR------GNKVAIKMLKEIKSRQA--TQQFLAEASVMTTL-SHTNLVGLIGVSL-DESP--IYLVTEFMGKGALEQYLRT
. .  .||.|.||||..|...      . .||.|||||  . ..   . |..||..|..| .| |.| |.|| . .. |  ||.|.|.| .| |  |||.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

R---GRSVITKQNQIDFARNVCNGMVYLESKNFVHRDLASRNVLLSDELVAK
.   .... .|.  ..... ...|| ||||||..||||| ||.|.....|.|
HREDKQPLTMKD-LLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVK
Kinase AqueK252.AA Src 165-301 43 1.2e-53 180.56 In-house 1-137 (255) Show / Hide 
Range on Protein: 165-301
Range on HMM: 1-137/255
Sequence Identity: 43% (61 aa)

LDMKSTLGKGEFGEVWLGEYRG-NKVAIKMLKEIKSRQATQQFLAEASVMTTLSHTNLVGLIGVSLDESPIYLVTEFMGKGALEQYLR-TRGRSVITKQN
. ..  ||.| ||||| | ..|  |||.| ||.     ....||.|| .|..|.| .|| |  |  .| ||| |||.| .| | .||. ..  . .  ..
IKLCRKLGQGQFGEVWMGYWNGNTKVAVKTLKPGT--MSPEAFLQEAQIMKKLRHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKKDGEGRHLHLPQ

QIDFARNVCNGMVYLESKNFVHRDLASRNVLLSDELVAK
.||.|  | .|| ||||.|..||||| |||| ....|.|
LIDMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCK
Kinase AqueK252.AA TK 165-301 19 2.5e-52 173.31 In-house 1-291 (486) Show / Hide 
Range on Protein: 165-301
Range on HMM: 1-291/486
Sequence Identity: 19% (57 aa)

LDMKSTLGKGEFG---EVWLGEYRGN---------------------------KVAIKMLKEIKSRQATQQFL-------------AEASVMTTLS----
. .  .||.|.||   ||..||.||                            .||.|||||  . .....|.             .||..|  ..    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HTNLVGLIGVSLDE------------SPIYLVTEFMGKGA----LEQYLRTRG----------------------------------------------
 | |.| |.||....             |...|.|.| .|     | .|||..                                               
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

----------------------------RSVITKQNQIDFARNVCNGMVYLESK------NFVHRDLASRNVLLSDELV-----------AK
                            .. .| . .. ... ...|| ||.||      |||||||| ||.|.....|           .|
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCK
Kinase AqueK252.AA Csk 302-380 59 1.8e-51 173.92 In-house 173-251 (251) Show / Hide 
Range on Protein: 302-380
Range on HMM: 173-251/251
Sequence Identity: 59% (47 aa)

KFSNKSDVWSFGIFLWELYSYGRVPYPRVPANDIMQFVERGYRMDPPDGCPPVIYQIMKDCWQADPNARPNFTRIMKSL
|||.|||||||||.|||.||.|||||||.|  |. . ||.||||..|.|||| .|..||.||...|  || | .. . |
KFSTKSDVWSFGILLWEIYSFGRVPYPRIPLKDVVKHVEKGYRMEAPEGCPPHVYKVMKQCWHLNPAKRPTFRQVREQL
Kinase AqueK252.AA Src-Unclassified 165-293 39 5.3e-44 148.73 In-house 1-151 (284) Show / Hide 
Range on Protein: 165-293
Range on HMM: 1-151/284
Sequence Identity: 39% (59 aa)

LDMKSTLGKGEFGEVWLGEYRG-NKVAIKMLKEIKSRQ-ATQQFL--------AEASVMTTLSHTNLVGLIGVSLDESPIYLVTEFMGKGALEQYLRTRG
.  .  || | |||||.| .||   ||.| ...  | . .. .||        .|| .|. ..| ||| | .|  .| |.| .||.| .| | |.||. |
VHLLRKLGRGQFGEVWYGKWRGKVDVAVKTMRPGHSETMSPEAFLHVKILNFCQEAQIMKKCRHQNLVHLYAVCSQEEPYYIITEYMINGSLLQWLREGG

RSVITKQNQ------------IDFARNVCNGMVYLESKNFVHRDLASRNVL
 .    |              .| |  | .|| |||||  |||||| ||||
GQYLHIQDMSEETGRKNVLIGVDIAAQVASGMMYLESKKYVHRDLAARNVL
Kinase AqueK252.AA SFK-Src 165-301 44 1.6e-43 126.46 In-house 1-136 (259) Show / Hide 
Range on Protein: 165-301
Range on HMM: 1-136/259
Sequence Identity: 44% (62 aa)

LDMKSTLGKGEFGEVWLGEYRGN-KVAIKMLKEIKSRQATQQFLAEASVMTTLSHTNLVGLIGVSLDESPIYLVTEFMGKGALEQYLRT-RGRSVITKQN
  ... || | ||.|| |   .   ||.| ||        . ||.|| ||  | |.||. |  |  |  ||| .|| |  | |  ||.  .|||  . . 
IRLEKKLGSGQFGDVWKGRWNNTTEVAVKTLKP--GAMSAEEFLQEAQVMKKLRHPNLIQLYAVCTDGEPIYIITELMKYGSLLDYLHEPHGRS-LRMPQ

QIDFARNVCNGMVYLESKNFVHRDLASRNVLLSDELVAK
 .| | .|  || ||| .|||||||| ||||  |  | |
LVDMAAQVAHGMAYLEAQNFVHRDLAARNVLVGDNNVCK
Kinase AqueK252.AA Pkinase_Tyr 302-380 46 3.8e-43 146.74 Pfam 190-270 (270) Show / Hide 
Range on Protein: 302-380
Range on HMM: 190-270/270
Sequence Identity: 46% (38 aa)

KFSNKSDVWSFGIFLWELYSYGRVP-YPRVPANDIMQFV-ERGYRMDPPDGCPPVIYQIMKDCWQADPNARPNFTRIMKSL
||. ||||||||. .||...||. | || .. ....... |.||||..|..||. ||..||.||..||. || |. |   |
KFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase AqueK252.AA Tec 165-301 43 1.7e-41 142.73 In-house 1-137 (254) Show / Hide 
Range on Protein: 165-301
Range on HMM: 1-137/254
Sequence Identity: 43% (61 aa)

LDMKSTLGKGEFGEVWLGEYRGN-KVAIKMLKEIKSRQATQQFLAEASVMTTLSHTNLVGLIGVSLDESPIYLVTEFMGKGALEQYLRTRGRSVITKQ-N
| .   ||.| || | ||..|.. .|||||.||         |. || ||. ||| .|| | || . . |||.|||.| .| |  |||...   ....  
LTFMKELGSGQFGVVHLGKWRHQYDVAIKMIKE--GSMSEEDFIEEAKVMMKLSHPKLVQLYGVCSQQRPIYIVTEYMEHGCLLNYLREHKHHFQKNMAI

QIDFARNVCNGMVYLESKNFVHRDLASRNVLLSDELVAK
 ..    || || |||...|.||||| || | .|. | |
LLEMCQDVCEGMAYLERHCFIHRDLAARNCLVGDQCVVK
Kinase AqueK252.AA TK-Unique 165-301 31 8e-41 138.53 In-house 1-173 (294) Show / Hide 
Range on Protein: 165-301
Range on HMM: 1-173/294
Sequence Identity: 31% (55 aa)

LDMKSTLGKGEFGEVWLGEYRG--------NKVAIKMLKEIKSRQATQQFLAEASVMTTLS-HTNLVGLIGVSLDES-PIYLVTEFMGKGALEQYLRTRG
| .....|.|.||.|| ||..|        ..||.||||.  . .  |.|| |...|  |  | |.| ..|.. . . | ... |.. .| |. ||||..
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR

R------------------------SVITKQNQIDFARNVCNGMVYLES--KNFVHRDLASRNVLLSDELVAK
.                        . |. .  . ||  ...|| ||.|  |..|||||..|||||.. .|.|
PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCK
Kinase AqueK252.AA TK 302-380 29 1.1e-39 130.18 In-house 370-486 (486) Show / Hide 
Range on Protein: 302-380
Range on HMM: 370-486/486
Sequence Identity: 29% (34 aa)

KFSNKSDVWSFGIFLWELYSYGRVPYPR-VPA---------NDIMQFVERG--------------YRMDPPDGCP--------------PVIYQIMKDCW
||. ||||||||...||...||..||.  ..           ..|....||              .|| .|..||              ...|..|..||
KFTTKSDVWSFGVLMWEIFTYGQEPYYGGMSNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCW

QADPNARPNFTRIMKSL
..||. ||.|. . . |
HYDPEDRPTFSQLHEQL
Kinase AqueK252.AA Abl 165-301 40 1.2e-39 129.65 In-house 1-137 (252) Show / Hide 
Range on Protein: 165-301
Range on HMM: 1-137/252
Sequence Identity: 40% (56 aa)

LDMKSTLGKGEFGEVWLGEYR--GNKVAIKMLKEIKSRQATQQFLAEASVMTTLSHTNLVGLIGVSLDESPIYLVTEFMGKGALEQYLRTRGRSVITKQN
. ||  || | .|||. | ..  .. ||.| |||     . ..||.|| .|  . | ||| |.||   |.| |..|||| .| | .|||  .|. ..   
IMMKHKLGGGQYGEVYEGVWKRHDCTVAVKTLKE--DTMEVHEFLKEAAIMKEMKHPNLVQLLGVCTREPPFYIITEFMCYGNLLDYLRECDREELPAVV

QIDFARNVCNGMVYLESKNFVHRDLASRNVLLSDELVAK
 .  |  .  || |||...|.||||| || |.... . |
LLYMATQIASGMSYLEKRHFIHRDLAARNCLVGEHHIVK
Kinase AqueK252.AA SFK-Src 302-384 47 1.4e-38 111.55 In-house 175-259 (259) Show / Hide 
Range on Protein: 302-384
Range on HMM: 175-259/259
Sequence Identity: 47% (40 aa)

KFSNKSDVWSFGIFLWELYSYGRVPYPRVPANDIMQFVER--GYRMDPPDGCPPVIYQIMKDCWQADPNARPNFTRIMKSLEKEV
.|| ||||||||| . |.  |||.|||      ..|.|.|  ||||. | .||.  |.|| ||||  |  || |      .|   
RFSIKSDVWSFGILMMEIVTYGRIPYPGMTNMEVLQQVDRPEGYRMPCPPNCPDEYYKIMFDCWQHEPDDRPTFESLKWQMEDFF
Kinase AqueK252.AA UTK 165-301 30 2e-38 129.04 In-house 1-165 (296) Show / Hide 
Range on Protein: 165-301
Range on HMM: 1-165/296
Sequence Identity: 30% (50 aa)

LDMKSTLGKGEFGEVWLGEYRG-------NKVAIKMLK-EIKSRQATQ---QFLAEAS---VMTTLS-HTNLVGLIGVSLDESPIYLVTEFMGKGALEQY
.    .||.|.|||| .....         .||.| .. . ...|.     .|. ||    .|  .. | |...|.|| ..|.|...|||.| .| | .|
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSY

LRTRGRSV------ITKQNQIDFARNVCNGMVYLESKNFVHRDLASRNVLLSDE-------LVAK
||. ....       |.  ....|... .|| ||.|..||||||| ||.|. .        .|.|
LRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCK
Kinase AqueK252.AA UTK 302-380 40 1.5e-37 126.03 In-house 216-296 (296) Show / Hide 
Range on Protein: 302-380
Range on HMM: 216-296/296
Sequence Identity: 40% (33 aa)

KFSNKSDVWSFGIFLWELYSYGRVPYPRVPANDIMQFVERG--YRMDPPDGCPPVIYQIMKDCWQADPNARPNFTRIMKSL
.|..||||||||...||....||.|||   . .. ..|..|  ||| .|..||  .|..|..||..||  ||.| .. . .
RFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDFEDLVQQM
Kinase AqueK252.AA Src 302-380 51 7.5e-36 119.25 In-house 176-255 (255) Show / Hide 
Range on Protein: 302-380
Range on HMM: 176-255/255
Sequence Identity: 51% (41 aa)

KFSNKSDVWSFGIFLWELYSYGRVPYPRVPANDIMQFVERGYRMDPPDGCPPVIYQ-IMKDCWQADPNARPNFTRIMKSL
.|. ||||||||| |.|. .|||||||     . .| |||||||  |..||. .|. ||. ||..||  || | .. . |
RFTIKSDVWSFGILLTEIVTYGRVPYPGMTNHEVLQQVERGYRMPCPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL
Kinase AqueK252.AA TK-Unique 303-380 45 1.1e-35 120.57 In-house 216-294 (294) Show / Hide 
Range on Protein: 303-380
Range on HMM: 216-294/294
Sequence Identity: 45% (36 aa)

FSNKSDVWSFGIFLWELYSYGRVPYPRVPANDIMQFVERGYRMDPPDGC-PPVIYQIMKDCWQADPNARPNFTRIMKSL
.. ||||||||...||. ..|  |||..|. |||. ...||||. |..| .. .|..|| ||| .|  ||.|. | . |
HTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYRMPQPEHCCSHEMYNLMKSCWQWEPEERPSFRQIKHRL
Kinase AqueK252.AA Syk 165-301 39 1.3e-35 120.02 In-house 1-146 (257) Show / Hide 
Range on Protein: 165-301
Range on HMM: 1-146/257
Sequence Identity: 39% (58 aa)

LDMKSTLGKGEFGEVWLGEYRGN---------KVAIKMLKEIKSRQA-TQQFLAEASVMTTLSHTNLVGLIGVSLDESPIYLVTEFMGKGALEQYLRTRG
|     .|.|.|| |  | |. .         ||||||||.  .  | .| |..||.||  | |   | .||. . | .  .| |  . |.. .||   .
LVQDNEIGCGNFGSVHKGWYMMKSGAGEKQWIKVAIKMLKADHNQPADKQEFMREAQVMCQLDHPCIVRMIGICHAE-MMMMVMEMAELGPMHKYLQQHR

RSVITKQNQIDFAR-NVCNGMVYLESKNFVHRDLASRNVLLSDELVAK
 . || .| .      |  || |||.|.||||||| ||||| ..  ||
HE-ITANNVLELWHTQVAMGMCYLEEKHFVHRDLAARNVLLVNRHYAK
Kinase AqueK252.AA Syk 302-374 49 5.2e-34 114.46 In-house 185-257 (257) Show / Hide 
Range on Protein: 302-374
Range on HMM: 185-257/257
Sequence Identity: 49% (36 aa)

KFSNKSDVWSFGIFLWELYSYGRVPYPRVPANDIMQFVERGYRMDPPDGCPPVIYQIMKDCWQADPNARPNFT
||| ||||||||. .|| .|||  ||      ..|.|.| | ||  |.|||. .||.|..||  ..  || | 
KFSHKSDVWSFGVTMWEMFSYGQKPYGEMKGQEVMKFIENGHRMNCPNGCPQEMYQLMNKCWIYKWCDRPTFV
Kinase AqueK252.AA Abl 302-380 46 7.1e-34 110.03 In-house 174-252 (252) Show / Hide 
Range on Protein: 302-380
Range on HMM: 174-252/252
Sequence Identity: 46% (37 aa)

KFSNKSDVWSFGIFLWELYSYGRVPYPRVPANDIMQFVERGYRMDPPDGCPPVIYQIMKDCWQADPNARPNFTRIMKSL
||| ||||| ||. |||.  ||  ||| .  ... . .|.||||. |.|||| .|..|. ||| ..  || |. | . .
KFSSKSDVWAFGVLLWEIATYGMSPYPGIDLSHVYHKLEKGYRMERPEGCPPKVYELMRQCWQWSHTDRPSFKEIHHAM
Kinase AqueK252.AA S_TKc 165-387 22 6.4e-33 116.61 SMART 1-231 (231) Show / Hide 
Range on Protein: 165-387
Range on HMM: 1-231/231
Sequence Identity: 22% (57 aa)

LDMKSTLGKGEFGEVWLGEYRG--NKVAIKMLKEIKSRQATQQFLAEASVMTTLSHTNLVGLIGVSLDESPIYLVTEFMGK--GALEQYLRTRGR----S
 ..  ..||| ||.|...  ..   .||||..|        .... | ...    | |.| |..|  | . .|.|.|...   | | .|.. |||    .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

VITKQNQIDFARNVCNGMVYLESKNFVHRDLASRNVLLSD-------------------------ELVAKKFSN-KSDVWSFGIFLWELYSYGRVPYPRV
...      ... .|... |. |....||||   |.||..                         |..  ...  |.|.||.|. |.|... |. |.|  
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDEHIKICDFGLARQLTTFCGTPWYMAPEVL--GYGKCKCDWWSCGCILYEMLC-GYPPFP--

PANDIMQFVERGYRMDPPDGCPPVIYQIMKDCWQADPNARPNFTRIMK--SLEKEVPPS
  . ... .            .|   .... |.| ||. ||    ...  .. |  |  
QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK252.AA Tec 302-382 37 2.7e-32 110.18 In-house 174-254 (254) Show / Hide 
Range on Protein: 302-382
Range on HMM: 174-254/254
Sequence Identity: 37% (30 aa)

KFSNKSDVWSFGIFLWELYSYGRVPYPRVPANDIMQFVERGYRMDPPDGCPPVIYQIMKDCWQADPNARPNFTRIMKSLEK
..| |||||.||.  || .| |..||..    .. . | .|.|.  |. |.  |||||..||.  |  || | . ......
RYSSKSDVWAFGVLMWEVFSCGKMPYENMSNSEVVEHVSQGHRLYRPHLCSMHIYQIMYHCWHEKPEERPTFQQLLRQITE
Kinase AqueK252.AA Src-Unclassified 302-380 47 5.8e-28 92.93 In-house 203-284 (284) Show / Hide 
Range on Protein: 302-380
Range on HMM: 203-284/284
Sequence Identity: 47% (39 aa)

KFSNKSDVWSFGIFLWELYSYGRVPYPRVPANDIMQFVERGYRMDPP--DGCPPVIYQ-IMKDCWQADPNARPNFTRIMKSL
.|| ||||||.|| |||.  .|..|||          |||||||  |   .||  ||. ||| || .||  || | .  . .
NFSIKSDVWSYGILLWEIMTKGQTPYPGMHNREVLEHVERGYRMPKPTNHYCPDYIYEDIMKKCWHKDPQRRPTFDTLYHYF
Kinase AqueK252.AA Pkinase 165-301 25 1.3e-20 73.98 Pfam 1-152 (293) Show / Hide 
Range on Protein: 165-301
Range on HMM: 1-152/293
Sequence Identity: 25% (38 aa)

LDMKSTLGKGEFGEVWLGEYRGNK--VAIKMLK--EIKSRQATQQFL-AEASVMTTLSHTNLVGLIGVSLDESPIYLVTEFMGKG----ALEQYLRTRGR
.  ....|.| ||.|...  .|.   ||.| .|  ..|| .  . .. .|...|  |.| | | |...  |.. ||.|.|....|     |  |..|. .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

SVI--TKQNQIDFARNVCNGMVYLESKNFVHRDLASRNVLLSDELVA----K
 ..  . .  ..... .. |. |. |....|||| . |.|.... .     |
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVK
Kinase AqueK252.AA Pkinase 306-380 22 1.2e-11 42.27 Pfam 192-293 (293) Show / Hide 
Range on Protein: 306-380
Range on HMM: 192-293/293
Sequence Identity: 22% (23 aa)

KSDVWSFGIFLWELYSYGRVPYPRV----PANDIMQFVERGYRMDPPDGCP-----------------------PVIYQIMKDCWQADPNARPNFTRIMK
|.|.||.|. |.|... || |.|      . .| || ..|  . ...  .|                       .   ...|.|.. ||. ||... |..
KVDMWSCGCILYEMLC-GRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQ

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