Gene AqueK267 (A.queenslandica)
AqueK267
Species: A.queenslandica
Alias: AqueK267
External Links:
Annotation:
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| AqueK267.AA | Protein | None | 260 | None | Fasta, JSON |
| AqueK267.kin_dom | Protein Kinase Domain | None | 94 | None | Fasta, JSON |
Protein domains of AqueK267.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Ank | AqueK267.AA | Ank | 15-38 | 33 | 56.694277 | 0.55 | Pfam | 1-24 (33) | Show / Hide |
Range on Protein: 15-38 Range on HMM: 1-24/33 Sequence Identity: 33% (8 aa) NTSTPLNEACWRGLKDEVQRLINK . ||| || .| .. |. |... DGFTPLHLACRCGHTEVVKMLLQH |
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| Kinase | AqueK267.AA | Pkinase_Tyr | 167-246 | 37 | 4.5e-33 | 112.65 | Pfam | 113-192 (270) | Show / Hide |
Range on Protein: 167-246 Range on HMM: 113-192/270 Sequence Identity: 37% (30 aa) LVKYMVDVAMGMHYIAERGLVHRDLAARNVLVGLGEICKVADFGLLRERPEDESVY-VSSSNIPCPIRWMPPEAISKRSFS |... ...|.|| | ......||||||||.||. . ..|..|||| | .... | ..... ..||.||.||.|. . |. LLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDI-YNDDYYYRKRGGGKLPIKWMAPECINYGKFT |
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| Kinase | AqueK267.AA | UTK | 133-246 | 29 | 8.1e-32 | 106.13 | In-house | 97-218 (296) | Show / Hide |
Range on Protein: 133-246 Range on HMM: 97-218/296 Sequence Identity: 29% (39 aa) LSHVVCGHSQKTQKLVLVNNSGLKNSPTKKSPDSLVKYMVDVAMGMHYIAERGLVHRDLAARNVLVGLG-------EICKVADFG---LLRERP------ |..... |.... |. . ........|.| ||.|....|.|||||||||.||. ..||.|||| . |. . LRSYLRRHRPTPP-----------ACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSN -EDES-VYVSSSNIPCPIRWMPPEAISKR-SFS ..|| | .... . ||||| |||. .. |. RYWESYYYMAQHQDRWPIRWMAPEALTHHTRFT |
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| Kinase | AqueK267.AA | TK | 163-251 | 28 | 1.5e-31 | 102.46 | In-house | 233-370 (486) | Show / Hide |
Range on Protein: 163-251
Range on HMM: 233-370/486
Sequence Identity: 28% (39 aa)
SPDSLVKYMVDVAMGMHYIAER------GLVHRDLAARNVLVGLGEI-----------CKVADFG--------LLRERPEDESVYVSS------------
.. |. .....| || |.... ..|||||||||.||| . . ||.|||| | |. ..|. |..|
TMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFE
-----------SNIPCPIRWMPPEAISKRSFSPS--KKI
|. |||||.||.. .| ||.. ...
DDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGK
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| Kinase | AqueK267.AA | Src | 174-246 | 50 | 1.5e-29 | 97.52 | In-house | 106-178 (255) | Show / Hide |
Range on Protein: 174-246 Range on HMM: 106-178/255 Sequence Identity: 50% (37 aa) VAMGMHYIAERGLVHRDLAARNVLVGLGEICKVADFGLLRERPEDESVYVSSSNIPCPIRWMPPEAISKRSFS || || |. .. ..|||||||||||| . .|||||||| | ||. .|.... ||.|. ||||. ..|. VAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLARLIKEDDDEYCARHGAKFPIKWTAPEAINYGRFT |
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| Kinase | AqueK267.AA | CTKA | 173-246 | 47 | 7.9e-27 | 87.07 | In-house | 139-212 (290) | Show / Hide |
Range on Protein: 173-246 Range on HMM: 139-212/290 Sequence Identity: 47% (35 aa) DVAMGMHYIAERGLVHRDLAARNVLVGLGEICKVADFGLLRERPEDESVYVSSSNIPCPIRWMPPEAISKRSFS ..| || | ||.|.||||||.||.|.| . |.||||. | . |..|| |.||| |||. || QIAAGMNYLAEMGFVHRDLACRNCLLGQYCHIKIADFGHGRTLRTESQYYYVSSQRVMPVRWMAPEALCFGKFS |
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| Kinase | AqueK267.AA | Ack | 167-246 | 36 | 3.1e-26 | 85.51 | In-house | 107-189 (266) | Show / Hide |
Range on Protein: 167-246 Range on HMM: 107-189/266 Sequence Identity: 36% (30 aa) LVKYMVDVAMGMHYIAERGLVHRDLAARNVLVGLGE-ICKVADFGLLRERPEDESVYVSSSNI--PCPIRWMPPEAISKRSFS | . . .|||| | ....||||||||.|. .. |..|||| | .. | |... . . |. |..||.. .| || LCDFCMQIAMGMRYLEMKRCIHRDLAARNILLFSDDRKVKICDFGLMRALGQNEDYYRMEFHRNLKVPFAWCAPECLRHRQFS |
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| Kinase | AqueK267.AA | TK-Unique | 163-247 | 37 | 3.9e-26 | 87.17 | In-house | 129-218 (294) | Show / Hide |
Range on Protein: 163-247 Range on HMM: 129-218/294 Sequence Identity: 37% (34 aa) SPDSLVKYMVDVAMGMHYIAE--RGLVHRDLAARNVLVGLGEICKVADFGLLRERPEDESVYVSS-SNIPCPIRWMPPEAIS--KRSF-SP || .|. .....|.|| |.|. .. |||||.|||||.. . .||..|||. |. . ||... | . |||||.||... .. . .. SPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYT-NGVYSMMCSQGRIPIRWMAPESLKCYHGMYHTT |
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| Kinase | AqueK267.AA | HMTK | 171-247 | 42 | 1.2e-25 | 86.44 | In-house | 134-213 (291) | Show / Hide |
Range on Protein: 171-247 Range on HMM: 134-213/291 Sequence Identity: 42% (34 aa) MVDVAMGMHYIAERGLVHRDLAARNVLVGLGEICKVADFGLLRERPEDESVYVSSSNI-PCPIRWMPPEAIS--KRSFSP .| .| || |||. ..||.||||||.||| . ..|.||||| | .... .... . ||.|| ||| . .. ||. CVQCASGMAYIASQRMVHMDLAARNCLVGHNNQVKIADFGLTRRLDPGQDYWHLRKHMVKLPIKWMAPEAMDGKRKIFSE |
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| Kinase | AqueK267.AA | KIN6 | 167-246 | 40 | 1.5e-25 | 81.21 | In-house | 146-228 (305) | Show / Hide |
Range on Protein: 167-246 Range on HMM: 146-228/305 Sequence Identity: 40% (34 aa) LVKYMVDVAMGMHYIAERGLVHRDLAARNVLVGLGE---ICKVADFGLLRERPEDESVYVSSSNIPCPIRWMPPEAISKRSFS |.. . .. || |.. ....||||||||||| | ||. |||| |. |.. |.| . ||.|| ||.. . || LYMFAWQICDGMEYLHSKNCIHRDLAARNVLVTEGCRMKTCKISDFGLCRYPYMDQFQYTSKGGRYLPIKWMAPECLKHYEFS |
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| Kinase | AqueK267.AA | SRM | 167-246 | 46 | 3e-25 | 81.25 | In-house | 99-176 (253) | Show / Hide |
Range on Protein: 167-246 Range on HMM: 99-176/253 Sequence Identity: 46% (37 aa) LVKYMVDVAMGMHYIAERGLVHRDLAARNVLVGLGEICKVADFGLLRERPEDESVYVSSSNIPCPIRWMPPEAISKRSFS |. . || || | |. .|||||||||||| . .|||.|||| | .| .| |.. |..| |||...| .| LLDFACQVAEGMCYLEEQNYIHRDLAARNVLVGDNNLCKVGDFGLARLIKDD--IYSPSHDHNIPYKWTAPEAANYRHYS |
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| Kinase | AqueK267.AA | Eph | 167-248 | 43 | 2.8e-24 | 78.32 | In-house | 107-190 (264) | Show / Hide |
Range on Protein: 167-248 Range on HMM: 107-190/264 Sequence Identity: 43% (37 aa) LVKYMVDVAMGMHYIAERGLVHRDLAARNVLVGLGEICKVADFGLLRE-RPED--ESVYVSSSNIPCPIRWMPPEAISKRSFSPS || . .| || | .. . |||||||||.|| .|||.|||| |. . .. | .| .. .|||| ||||. | |... LVGMLRGIASGMKYLSDMNYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPSVEATYTTR-GGKIPIRWTAPEAIAYRKFTSA |
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| TyrKc | AqueK267.AA | TyrKc | 86-260 | 16 | 4.9e-09 | -76.6 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 86-260
Range on HMM: 1-280/280
Sequence Identity: 16% (48 aa)
LHMAS----------YKGHLNIAQYLVNECHVDPDIADSYGNTGLLYS------ALG-GHVDLMLSHVVCGHS-------QKTQKLVLVNNSG-----LK
... |||... | | .. | ... || | . . || .. . .. | |.
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA--------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR
NSPTKKSPDSLVKYMVDVAMGMHYIAERGLVHRDLAARNVLVGLGEICKVADFGLLRERPED------ESVYVS----SSNIPCPIRWMPPEAISKRSFS
.. | ... |.......| || |.......||||||||.||| . ..|..|||| |. .| ...|.. ... . |||||.||.| .. |.
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT
-----------------------PS---------------------KKILR-------------------------------KILLKIL
| .. . . ...
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
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| Ank | AqueK267.AA | Ank | 81-114 | 29 | 3.1e-05 | 23.16 | Pfam | 1-33 (33) | Show / Hide |
Range on Protein: 81-114 Range on HMM: 1-33/33 Sequence Identity: 29% (10 aa) DGVISLHMASYKGHLNIAQYLVNECHVDPDIADS || ||.|...||......|.. . |... | DGFTPLHLACRCGHTEVVKMLLQ-HGADVNAQDD |
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| Ank | AqueK267.AA | Ank | 47-80 | 29 | 0.138916 | 9.97 | Pfam | 1-33 (33) | Show / Hide |
Range on Protein: 47-80 Range on HMM: 1-33/33 Sequence Identity: 29% (10 aa) NGWSPPLAASYGGHIDVLCLLIDVYHCDPSQGDD .|..| |.. ||..|. .|.. . .|. || DGFTPLHLACRCGHTEVVKMLLQ-HGADVNAQDD |
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