Gene AqueK291 (A.queenslandica)

AqueK291

Species: A.queenslandica
Alias: AqueK291
External Links:
Annotation:

Classification

Group: TK
Family: Eph

Sequence

Name Sequence Type Origin Length Description Download
AqueK291.AA Protein None 168 None Fasta, JSON
AqueK291.kin_dom Protein Kinase Domain None 106 None Fasta, JSON

Protein domain

Protein domains of AqueK291.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase AqueK291.AA Pkinase_Tyr 51-163 46 3.5e-66 224.77 Pfam 113-227 (270) Show / Hide 
Range on Protein: 51-163
Range on HMM: 113-227/270
Sequence Identity: 46% (53 aa)

LLSFCRQIASGMEYLSKKGFVHRDLAARNILMTDHGMCKIADFGMSRDLHDENYY-VSTTAKRIPIKWTAPEALHFKRYSSASDVWSYGVVMYEIWSLGH
||..|.|||.|||||. |...||||||||.| |. . .||.|||..||.... || ....  ..||||.|||..........|||||.||.|.|| ..| 
LLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWSFGVLMWEIFTYGE

KP-FENCTNQEVCNQ
.| .....|.||...
QPTYPGMSNEEVYEY
Kinase AqueK291.AA TK 51-168 32 2.3e-62 207.59 In-house 237-416 (486) Show / Hide 
Range on Protein: 51-168
Range on HMM: 237-416/486
Sequence Identity: 32% (59 aa)

LLSFCRQIASGMEYLSKK------GFVHRDLAARNILMTDHGM-----------CKIADFGMS--------RDLHDENYYVSTT----------------
|| .|.|||.|||||..|      .||||||||||.| ....            |||||||.|        ||.... .|....                
LL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPW

--------AKRIPIKWTAPEALH---------FKRYSSASDVWSYGVVMYEIWSLGHKPFEN-CTNQEVCN----QKVVER
          ..||.|.|||.|          .......|||||.||.|.||...| .|.    .||.|..    | |.|.
QDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMSNQDVWKDGDNQEVMEY
Kinase AqueK291.AA UTK 51-163 43 1.7e-55 188.29 In-house 120-252 (296) Show / Hide 
Range on Protein: 51-163
Range on HMM: 120-252/296
Sequence Identity: 43% (58 aa)

LLSFCRQIASGMEYLSKKGFVHRDLAARNILMTDHG-------MCKIADFG---MSRDLH---------DENYYVSTTAKRIPIKWTAPEALHFK-RYSS
.|.....||.||.||. .|||||||||||.| ..|.        |||||||   |||...         . .|| .. ..|.||.|.|||||    |...
RLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQDRWPIRWMAPEALTHHTRFTT

ASDVWSYGVVMYEIWSLGHKPFENCTNQEVCNQ
.|||||.|||..|||. | .|... .|..|. |
KSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQ
Kinase AqueK291.AA Eph 58-160 52 9.3e-52 172.07 In-house 114-219 (264) Show / Hide 
Range on Protein: 58-160
Range on HMM: 114-219/264
Sequence Identity: 52% (56 aa)

IASGMEYLSKKGFVHRDLAARNILMTDHGMCKIADFGMSRDLHDEN----YYVSTTAKRIPIKWTAPEALHFKRYSSASDVWSYGVVMYEIWSLGHKPFE
||||| |||  ..|||||||||||   . .||..|||.|| | |.      | ..   .|||.||||||. .....|||||||||.|| |. | | .|. 
IASGMKYLSDMNYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPSVEATYTTR-GGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYW

NCTNQEV
. .||.|
DMSNQDV
Kinase AqueK291.AA TK-Unique 48-160 46 1.4e-51 176.12 In-house 130-248 (294) Show / Hide 
Range on Protein: 48-160
Range on HMM: 130-248/294
Sequence Identity: 46% (55 aa)

PGLLLSFCRQIASGMEYLSK--KGFVHRDLAARNILMTDHGMCKIADFGMSRDLHDENYYVST-TAKRIPIKWTAPEALH--FKRY-SSASDVWSYGVVM
|..|..|. |||.|||||..  |..|||||.|||.|.|....|||.||||.||..... |... . .||||.| |||.|    . | .. |||||.||.|
PKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMCSQGRIPIRWMAPESLKCYHGMYHTTKSDVWSFGVLM

YEIWSLGHKPFENCTNQEV
.|| .||  |. .  . ..
WEIFTLGACPYPGMPWKDI
Kinase AqueK291.AA CTKA 53-162 49 3.2e-50 166.86 In-house 135-245 (290) Show / Hide 
Range on Protein: 53-162
Range on HMM: 135-245/290
Sequence Identity: 49% (55 aa)

SFCRQIASGMEYLSKKGFVHRDLAARNILMTDHGMCKIADFGMSRDLHDE-NYYVSTTAKRIPIKWTAPEALHFKRYSSASDVWSYGVVMYEIWSLGHKP
.  .||| ||.||.  ||||||||.||.|.      |||||| .| |  |  ||..    ..|. | ||||| | ..|.|||||..||...|| | | ||
YMAMQIAAGMNYLAEMGFVHRDLACRNCLLGQYCHIKIADFGHGRTLRTESQYYYVSSQRVMPVRWMAPEALCFGKFSCASDVWAFGVLLWEIMSMGEKP

FENCTNQEVCN
.   . ||||.
WRHMSDQEVCQ
Kinase AqueK291.AA Src 51-163 43 1.4e-49 166.63 In-house 99-212 (255) Show / Hide 
Range on Protein: 51-163
Range on HMM: 99-212/255
Sequence Identity: 43% (50 aa)

LLSFCRQIASGMEYLSKKGFVHRDLAARNILMTDHGMCKIADFGMSRDLH-DENYYVSTTAKRIPIKWTAPEALHFKRYSSASDVWSYGVVMYEIWSLGH
|...  |.|.||.||... ..||||||||.|  .. .||.||||  | .  |.. |.. .  ..|||||||||... |..  |||||.|. ..|| . | 
LIDMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLARLIKEDDDEYCARHGAKFPIKWTAPEAINYGRFTIKSDVWSFGILLTEIVTYGR

KPFENCTNQEVCNQ
 | .  ||.||  |
VPYPGMTNHEVLQQ
Kinase AqueK291.AA Fer 54-168 39 1.6e-48 163.35 In-house 116-241 (283) Show / Hide 
Range on Protein: 54-168
Range on HMM: 116-241/283
Sequence Identity: 39% (50 aa)

FCRQIASGMEYLSKKGFVHRDLAARNILMTDHGM---CKIADFGMSRDLHDENYYVSTT--AKRIPIKWTAPEALHFKRYSSASDVWSYGVVMYEIWSLG
.| |.|.||||| .|. .|||.||||.|.....    |||.||||||.. |. |  .    |...||.|.|||.. .. ||...||||.||...|| . |
MCYQAACGMEYLHSKNCIHRDIAARNCLYHKDKVKKKCKISDFGMSRQCSDYGYDYKMKEKACKVPIRWLAPETWQTGIYSPKTDVWSFGVMCWEIFTNG

HKPFEN------CTNQEVCNQKVVER
 .|...      .||..  ..|....
AEPYPGQPHGMKMTNVKKQARKWIIK
Kinase AqueK291.AA Tec 49-163 46 2.2e-48 167.03 In-house 97-210 (254) Show / Hide 
Range on Protein: 49-163
Range on HMM: 97-210/254
Sequence Identity: 46% (54 aa)

GLLLSFCRQIASGMEYLSKKGFVHRDLAARNILMTDHGMCKIADFGMSRDLHDENYYVSTTAKRIPIKWTAPEALHFKRYSSASDVWSYGVVMYEIWSLG
..||. | ..  ||.|| ...|.|||||||| |  | .  |..||||.|   |  |  |. .|  |.|| .|| .|. |||| ||||..|| | |..|.|
AILLEMCQDVCEGMAYLERHCFIHRDLAARNCLVGDQCVVKVSDFGMTRYVLDDQYTSSVGTK-FPVKWCPPEVFHYSRYSSKSDVWAFGVLMWEVFSCG

HKPFENCTNQEVCNQ
  |.|| .| ||  .
KMPYENMSNSEVVEH
Kinase AqueK291.AA Syk 57-163 50 7.6e-48 162.77 In-house 114-221 (257) Show / Hide 
Range on Protein: 57-163
Range on HMM: 114-221/257
Sequence Identity: 50% (54 aa)

QIASGMEYLSKKGFVHRDLAARNILMTDHGMCKIADFGMSRDL-HDENYYVSTTAKRIPIKWTAPEALHFKRYSSASDVWSYGVVMYEIWSLGHKPFENC
|.|.|| ||  | ||||||||||.| .. .  || |||||. |  |..||..||. . |.|| |||   .   |..|||||.|| | |  |.| ||    
QVAMGMCYLEEKHFVHRDLAARNVLLVNRHYAKISDFGMSKALGADSQYYQATTHGKWPVKWYAPECIYYYKFSHKSDVWSFGVTMWEMFSYGQKPYGEM

TNQEVCNQ
..|||  .
KGQEVMKF
Kinase AqueK291.AA HMTK 51-160 45 1.3e-46 160.61 In-house 130-245 (291) Show / Hide 
Range on Protein: 51-160
Range on HMM: 130-245/291
Sequence Identity: 45% (53 aa)

LLSFCRQIASGMEYLSKKGFVHRDLAARNILMTDHGMCKIADFGMSRDLH-DENYYVSTTAK-RIPIKWTAPEALH--FKRYSSASDVWSYGVVMYEIWS
.|.||.|.||||.|......||.||||||.| ..   .|||||| .| |  ...|......  . |||| ||||.    |. | .||||..||.| |||.
QLYFCVQCASGMAYIASQRMVHMDLAARNCLVGHNNQVKIADFGLTRRLDPGQDYWHLRKHMVKLPIKWMAPEAMDGKRKIFSEKSDVWAFGVTMWEIWM

LGHKPFE--NCTNQEV
 |  |.|     |.||
YGEQPYESQQIKNKEV
Kinase AqueK291.AA Pkinase 53-143 31 4.9e-18 64.87 Pfam 112-204 (293) Show / Hide 
Range on Protein: 53-143
Range on HMM: 112-204/293
Sequence Identity: 31% (30 aa)

SFCRQIASGMEYLSKKGFVHRDLAARNILMTDHGMC----KIADFGMSRDLHDENYYVSTTAKRIPIKWTAPEALH-FKRYSSASDVWSYGVVMYE
....||..|.||. ..|..||||   |||. ..| .    ||.||| .. .  .  .. .|     . . ||| .   . |....|.||.|...||
FYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYE
TyrKc AqueK291.AA TyrKc 18-165 23 1e-16 47.41 SMART 1-280 (280) Show / Hide 
Range on Protein: 18-165
Range on HMM: 1-280/280
Sequence Identity: 23% (65 aa)

DCLYHQLSS-----------------KGFREIAKKDIQP-----GEL------------VASTV----------------------------------PG
  | ..| .                 |  .| |..|.        .|            |...                                   . 
ITLGKKLGEGAFGEVYKGTWKIQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKLCMK

LLLSFCRQIASGMEYLSKKGFVHRDLAARNILMTDHGMCKIADFGMSRDLHDE-------NYYVSTT--AKR--IPIKWTAPEALHFKRYSSASDVWSYG
 ||||| |||.|||||..|...||||||||.| .. . .||.|||.|||..|.        ||....   ..  .||.|.|||.. .......|||||.|
DLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDVWSFG

VVMYEIWSLGHKPFEN-----CTNQEVC-------------N-----------------------------------QKV
|.|.|| ..| .| ..     ..||||              |                                   .. 
VCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
S_TKc AqueK291.AA S_TKc 3-166 15 2.1e-07 -68.37 SMART 1-231 (231) Show / Hide 
Range on Protein: 3-166
Range on HMM: 1-231/231
Sequence Identity: 15% (39 aa)

FVQEEPL------------------------------------------------YWQPGDDTDCLYHQLSSKGFREIAKKDIQPGELVAS--TVPGLLL
.   ...                                                ..|   |  ..   . . .  .  .   . |         .    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIKEHIRREIQILKKHHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HAR

SFCRQIASGMEYLSKKGFVHRDLAARNILMTDHGMCKIADFGMSRDLHDENYYVSTTAKRIPIKWTAPEALHFKRYSS-ASDVWSYGVVMYEIWSLGHKP
....||....||. ..|..||||   |||...    ||.|||..| |         |       . ||| |    |.  ..|.|| |...||  . |  |
FYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLC-GYPP

FE------------------------N----CTNQEVCN-------QKVV
|.                        .     |  |. .          .
FPQMQMMFKKIGSPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF