Gene AqueK295 (A.queenslandica)

AqueK295

Species: A.queenslandica
Alias: AqueK295
External Links:
Annotation:

Classification

Group: TK
Family: Eph

Sequence

Name Sequence Type Origin Length Description Download
AqueK295.AA Protein None 518 None Fasta, JSON
AqueK295.kin_dom Protein Kinase Domain None 132 None Fasta, JSON

Protein domain

Protein domains of AqueK295.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Pkinase_Tyr AqueK295.AA Pkinase_Tyr 365-479 42 7.1e-57 193.24 Pfam 152-270 (270) Show / Hide 
Range on Protein: 365-479
Range on HMM: 152-270/270
Sequence Identity: 42% (50 aa)

IADFGMSRDLQDESYY--ISQSKKIPIKWTAPEALHYKKYSSASDVWSYGAVMYEIWSLGCKP-FEKSTNQESIRLV-DSGYRLPPPPGCPKPMYKLMIQ
|.|||..||.....||   ... |.||||.|||...|.|....|||||.| .|.|| ..| .| ..  .|.| .... ..|||.|.|..||...|.|| |
ICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQ

CWNPNSHNRPSFSDISSSL
||...  .||.||.| . |
CWHYDPEDRPTFSEIHEQL
Kinase AqueK295.AA Eph 365-479 47 6.8e-55 182.77 In-house 146-264 (264) Show / Hide 
Range on Protein: 365-479
Range on HMM: 146-264/264
Sequence Identity: 47% (57 aa)

IADFGMSRDLQDES----YYISQSKKIPIKWTAPEALHYKKYSSASDVWSYGAVMYEIWSLGCKPFEKSTNQESIRLVDSGYRLPPPPGCPKPMYKLMIQ
..|||.|| |.|..     | ... ||||.||||||. |.|..||||||||| || |. | | .|.   .||. |  .. |||||||..||.....|| .
VSDFGLSRVLEDDPSVEATYTTRGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEQGYRLPPPMDCPEALHQLMLD

CWNPNSHNRPSFSDISSSL
||    ..|| |..| | |
CWQKDRNHRPHFQQIVSIL
Kinase AqueK295.AA TK 365-479 27 3.5e-52 172.85 In-house 292-486 (486) Show / Hide 
Range on Protein: 365-479
Range on HMM: 292-486/486
Sequence Identity: 27% (53 aa)

IADFGMS--------RDL-QDESYYISQ------------------------SKKIPIKWTAPEALH---------YKKYSSASDVWSYGAVMYEIWSLG
|||||.|        ||. .|. || ..                        . |.||.|.|||.|          |.|....|||||.| .|.||...|
IADFGLSRQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYG

CKPFEK-STN---------QESIRLVDSG--------------YRLPPPPGCP--------------KPMYKLMIQCWNPNSHNRPSFSDISSSL
 .|.    .|         || .... .|              .|.|.||.||              . .| || |||...   ||.||.. . |
QEPYYGGMSNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase AqueK295.AA Src 365-479 40 8.1e-47 157.06 In-house 138-255 (255) Show / Hide 
Range on Protein: 365-479
Range on HMM: 138-255/255
Sequence Identity: 40% (48 aa)

IADFGMSRDLQ--DESYYISQSKKIPIKWTAPEALHYKKYSSASDVWSYGAVMYEIWSLGCKPFEKSTNQESIRLVDSGYRLPPPPGCPKPMYK-LMIQC
.||||  | ..  |. |  ..  |.|||||||||..| ...  |||||.|  ..|| . |  | .  ||.| .. |. |||.| |..||. .|. .| ||
VADFGLARLIKEDDDEYCARHGAKFPIKWTAPEAINYGRFTIKSDVWSFGILLTEIVTYGRVPYPGMTNHEVLQQVERGYRMPCPHNCPDELYEQIMLQC

WNPNSHNRPSFSDISSSL
|.     || |  . . |
WHKDPEQRPTFEYLQWFL
Kinase AqueK295.AA SFK-Src 365-472 45 2.6e-46 134.9 In-house 137-248 (259) Show / Hide 
Range on Protein: 365-472
Range on HMM: 137-248/259
Sequence Identity: 45% (51 aa)

IADFGMSRDLQDESY-YISQSK-KIPIKWTAPEALHYKKYSSASDVWSYGAVMYEIWSLGCKPFEKSTNQESIRLVDS--GYRLPPPPGCPKPMYKLMIQ
..|||||| | ...  |  .   | |||||||||  . ..|  |||||.|  |.||  .| .|..  ||.| .. ||   |||.| ||.||  .||.|..
VGDFGMSRVLAQDDEGYTAHEGAKFPIKWTAPEAMNMNRFSIKSDVWSFGILMMEIVTYGRIPYPGMTNMEVLQQVDRPEGYRMPCPPNCPDEYYKIMFD

CWNPNSHNRPSF
||  .  .|| |
CWQHEPDDRPTF
Kinase AqueK295.AA UTK 365-479 39 8.2e-46 154.71 In-house 166-296 (296) Show / Hide 
Range on Protein: 365-479
Range on HMM: 166-296/296
Sequence Identity: 39% (52 aa)

IADFG---MSRDLQD--------ES-YYISQ-SKKIPIKWTAPEALHYK-KYSSASDVWSYGAVMYEIWSLGCKPFEKSTNQESIRLVDSG--YRLPPPP
|||||   |||....        || || .|  ...||.|.||||| .  .....|||||.| |..|||. | .|..  .|.. .  |  |  ||.|.|.
IADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQDRWPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPW

GCPKPMYKLMIQCWNPNSHNRPSFSDISSSL
.|| |.|.|| .||...  .||.| |. . .
DCPHPVYRLMHRCWHYDPQERPDFEDLVQQM
Kinase AqueK295.AA SRM 365-480 42 3.5e-44 145.6 In-house 138-253 (253) Show / Hide 
Range on Protein: 365-480
Range on HMM: 138-253/253
Sequence Identity: 42% (49 aa)

IADFGMSRDLQDESYYISQSKKIPIKWTAPEALHYKKYSSASDVWSYGAVMYEIWSLGCKPFEKSTNQESIRLVDSGYRLPPPPGCPKPMYKLMIQCWNP
..|||. | . |  |  | . .||.|||||||. |  ||  |||||.|  ..|. . |  |..  || | .  .| |||.| |  ||   .|||..||  
VGDFGLARLIKDDIYSPSHDHNIPYKWTAPEAANYRHYSQKSDVWSFGILLHEMFTYGQCPYPGMTNHETFQQIDRGYRMPCPAECPPEVHKLMLECWCR

NSHNRPSFSDISSSLS
    ||.| |    |.
DPEQRPCFKDLREKLT
Kinase AqueK295.AA CTKA 365-479 41 6.8e-42 138.47 In-house 172-290 (290) Show / Hide 
Range on Protein: 365-479
Range on HMM: 172-290/290
Sequence Identity: 41% (49 aa)

IADFGMSRDLQDE--SYYISQSKKIPIKWTAPEALHYKKYSSASDVWSYGAVMYEIWSLGCKPFEKSTNQESIRLVDSG--YRLPPPPGCPKPMYKLMIQ
||||| .| |. |   ||.| .  .|. | |||||   |.|.|||||..| ...|| | | ||. . . ||   .. |.   |||.|. ||  .| .|  
IADFGHGRTLRTESQYYYVSSQRVMPVRWMAPEALCFGKFSCASDVWAFGVLLWEIMSMGEKPWRHMSDQEVCQAYTSHGMRRLPVPRNCPQVLYHCMQE

CWNPNSHNRPSFSDISSSL
|| .    ||.|  .  .|
CWKFEPNQRPTFETLQRML
Kinase AqueK295.AA Fer 365-480 32 1e-41 139.85 In-house 155-283 (283) Show / Hide 
Range on Protein: 365-480
Range on HMM: 155-283/283
Sequence Identity: 32% (42 aa)

IADFGMSRDLQDESYYIS---QSKKIPIKWTAPEALHYKKYSSASDVWSYGAVMYEIWSLGCKPFEK------STNQ--ESIRL-VDSGYRLPPPPGCPK
|.||||||.. |. |  .    ..|.||.|.|||.. .. ||...||||.| ...|| . | .|..        ||.  . ..  ...||..|.|...|.
ISDFGMSRQCSDYGYDYKMKEKACKVPIRWLAPETWQTGIYSPKTDVWSFGVMCWEIFTNGAEPYPGQPHGMKMTNVKKQARKWIIKKGYMMPMPNHMPP

PMYKLMI-QCWNPNSHNRPSFSDISSSLS
.....|  |||. .  .||....|   | 
EIMQIMMKQCWQKDPEDRPTMKEICQKLK
Kinase AqueK295.AA TK-Unique 365-479 39 2.4e-41 140.33 In-house 174-294 (294) Show / Hide 
Range on Protein: 365-479
Range on HMM: 174-294/294
Sequence Identity: 39% (48 aa)

IADFGMSRDLQDESYYISQ-S-KKIPIKWTAPEALH--YKKY-SSASDVWSYGAVMYEIWSLGCKPFEKSTNQESIRLVDSGYRLPPPPGC-PKPMYKLM
|.||||.||....  |... | ..|||.| |||.|   .. | .. |||||.| .|.|| .||  |. .  . . ....  |||.| |..| .. ||.||
ICDFGMARDVYTNGVYSMMCSQGRIPIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYRMPQPEHCCSHEMYNLM

IQCWNPNSHNRPSFSDISSSL
..||. . . ||||..| . |
KSCWQWEPEERPSFRQIKHRL
Kinase AqueK295.AA Syk 365-473 44 1.6e-40 137.16 In-house 147-257 (257) Show / Hide 
Range on Protein: 365-473
Range on HMM: 147-257/257
Sequence Identity: 44% (49 aa)

IADFGMSRDL-QDESYYISQSK-KIPIKWTAPEALHYKKYSSASDVWSYGAVMYEIWSLGCKPFEKSTNQESIRLVDSGYRLPPPPGCPKPMYKLMIQCW
| |||||. |  |..|| ...  | |.|| |||   | | |..|||||.|  | |  |.| ||  . ..|| . ....| |.. |.|||. || || .||
ISDFGMSKALGADSQYYQATTHGKWPVKWYAPECIYYYKFSHKSDVWSFGVTMWEMFSYGQKPYGEMKGQEVMKFIENGHRMNCPNGCPQEMYQLMNKCW

NPNSHNRPSFS
     .|| |.
IYKWCDRPTFV
TyrKc AqueK295.AA TyrKc 247-479 21 9e-16 32.32 SMART 1-280 (280) Show / Hide 
Range on Protein: 247-479
Range on HMM: 1-280/280
Sequence Identity: 21% (69 aa)

IRFT-----------CHGIITNWIVVAPALVMPVIKIRHSNNLTTTAA--TLNTSASNAVRITSLLYNF-----TMSNE------------IAVQA----
|..            ..|. .                       .. |  .|. .|         .  |      |..             ...|     
ITLGKKLGEGAFGEVYKGTWK-----------------------IQVAVKMLKEDA---------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNF

---GDILMIESNATNYMYY---QQYNGPHNYRLGDNNELIALDTNDYPLISV-----------------------VVVWSQ----IADFGMSRDLQDE--
   . ....    . || .   ..|   |  .         | . |   ...                       . | ..    |.|||.|||. |.  
MYIEPLMIV----MEYMPHGDLKDYLRKHRPK---------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQ

-----SYYISQ---SKK--IPIKWTAPEALHYKKYSSASDVWSYGAVMYEIWSLGCKPFEK-----STNQESIRLVDSGYRLPPPPG--------CPKPM
     .|| ..   ..|  .||.|.|||.. |.|....|||||.| .|.|| ..| .| .       .||| |..|..|||.|.||         ||. |
QGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEM

YKLMIQCWNPNSHNRPSFSDISSSL
|..| |||. . ..||.||.| . .
YQIMKQCWHEDPEDRPTFSEIHECF
Kinase AqueK295.AA Pkinase 365-479 15 6.2e-10 36.2 Pfam 153-293 (293) Show / Hide 
Range on Protein: 365-479
Range on HMM: 153-293/293
Sequence Identity: 15% (23 aa)

IADFGMSRDLQDESYYISQSKKIPIKWTAPEALH-YKKYSSASDVWSYGAVMYEIWSLGCKPFEKS----TNQESIRLVDSGYRLPPPPGCP--------
|.||| .. ..  ..   ..    . . ||| .  ...|....|.||.| ..||  . |  ||  .    .  . . ...   . |..  .|        
ICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLC-GRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYF

---------------KPMYKLMIQCWNPNSHNRPSFSDISSS--L
               ... ...  |.... . ||.. .|  .  .
FFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
S_TKc AqueK295.AA S_TKc 269-480 15 7.1e-07 -76.11 SMART 15-231 (231) Show / Hide 
Range on Protein: 269-480
Range on HMM: 15-231/231
Sequence Identity: 15% (41 aa)

VIKIRHSNNLTTTAATLNTSASNAVRITSLLYNFTMSNEIAVQAGDILMIESNATNYMYYQQYNGPHNYR---LGDN--NELIALDTND--------YPL
| | || .          |    |. | .     .. .||..          |  .. .. |    | |    . |.   .|  .  .         .| 
VYKCRHKK----------TGRIVAIKIIK----EHIRREIQILKK----HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE

ISVVVVWSQI------------------------------ADFGMSRDLQDESYYISQSKKIPIKWTAPEALHYKKYSS-ASDVWSYGAVMYEIWSLGCK
  .  .  ||                              .|||..| |         .      . ||| |   .|.  ..|.|| | ..||  . |. 
-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDEHIKICDFGLARQL--------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLC-GYP

PFEKSTNQESIRLVDSGYRLPPPPGCPKPMYKLMIQCWNPNSHNRPSFSDISS--------SLS
||.  . |. ....            ....  .. .|.. .  .||.  ..             
PFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF