Gene AqueK297 (A.queenslandica)

AqueK297

Species: A.queenslandica
Alias: AqueK297
External Links:
Annotation:

Classification

Group: TK
Family: Eph

Sequence

Name Sequence Type Origin Length Description Download
AqueK297.AA Protein None 1528 None Fasta, JSON
AqueK297.kin_dom Protein Kinase Domain None 142 None Fasta, JSON

Protein domain

Protein domains of AqueK297.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Pkinase_Tyr AqueK297.AA Pkinase_Tyr 1372-1513 44 2.1e-61 208.61 Pfam 1-145 (270) Show / Hide 
Range on Protein: 1372-1513
Range on HMM: 1-145/270
Sequence Identity: 44% (66 aa)

IKVTDYLGSGQFGTVNKGVWT-TPTAGSVSVAIKTLNDNTSEDE--RVKFLQEAAIMGQF-HHPNVVKLHGVVT-IGHP--IMIVLELISGGDLKEYLNK
|.    ||.|.||.| ||.|.  |  . . ||.|.|........  | .|..||.|| |. ||||.|.|.||.|  | |  |.||.|.  .|||..|| |
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

FKPSPGELVLSSVPSILLSFCRQIASGMEYLSRKKFVHRDLAARNILVS
 .    |   .  .. ||..|.|||.|||||..|...||||||||.||.
HR----EDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVT
Kinase AqueK297.AA TK 1372-1513 25 3.6e-55 183.03 In-house 1-274 (486) Show / Hide 
Range on Protein: 1372-1513
Range on HMM: 1-274/486
Sequence Identity: 25% (69 aa)

IKVTDYLGSGQFG---TVNKGVWTT----------------------PTAGSVSVAIKTLN--DNTSEDERVK-----------FLQEAAIMGQFH----
|.. . ||.||||   .| || | .                      .. | . ||.|.|   |..|..|.             ||.||..| ...    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HPNVVKLHGVVTIG------------HPIMIVLELISGGD----LKEYLNKFKPSPGELVLSSV-----------------------------------
 |||.|.|.||.| |            .|.|||.|. ..||    |..|| | .|   .   ..                                    
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------PSILLS-------------------FCRQIASGMEYLSRK------KFVHRDLAARNILVS
              . ||.                   .|.|||.|||||..|      .||||||||||.||.
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVG
Kinase AqueK297.AA UTK 1372-1512 38 6e-52 175.99 In-house 1-151 (296) Show / Hide 
Range on Protein: 1372-1512
Range on HMM: 1-151/296
Sequence Identity: 38% (58 aa)

IKVTDYLGSGQFGTVNKGVWTTPT--AGSVSVAIKTLN-DNTSEDERV---KFLQEAA---IMGQFH-HPNVVKLHGVVTIGHPIMIVLELISGGDLKEY
..  . ||.|.||.|.|. .|...  .. . ||.|... . ....|.    .|. ||.   .|.||| ||||..| ||.| . |.|||.|. ..|||  |
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSY

LNKFKPSPGELVLSSVPSILLSFCRQIASGMEYLSRKKFVHRDLAARNILV
| . .|.|..  ..     .|.....||.||.||....||||||||||.||
LRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLV
Kinase AqueK297.AA Eph 1372-1514 44 2.1e-47 157.22 In-house 1-140 (264) Show / Hide 
Range on Protein: 1372-1514
Range on HMM: 1-140/264
Sequence Identity: 44% (66 aa)

IKVTDYLGSGQFGTVNKGVWTTP-TAGSV---SVAIKTLNDNTSEDERVKFLQEAAIMGQFHHPNVVKLHGVVTIGHPIMIVLELISGGDLKEYLNKFKP
||..  .|.|.|| | .|   .|  .  |    |||||| .  .| .|. || ||.||||| |||...| |||| . |.||| |    | | ..| .   
IKIEKVIGAGEFGEVCCGRLKLPSGKREVWVDPVAIKTLKAGYTEKQRWDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIVTEYMENGSLDSFLRQHD-

SPGELVLSSVPSILLSFCRQIASGMEYLSRKKFVHRDLAARNILVSA
  |...       |.   | ||||| |||   .||||||||||||..
--GQFTVIQ----LVGMLRGIASGMKYLSDMNYVHRDLAARNILVNS
Kinase AqueK297.AA Fer 1372-1514 35 4.6e-46 154.91 In-house 1-146 (283) Show / Hide 
Range on Protein: 1372-1514
Range on HMM: 1-146/283
Sequence Identity: 35% (55 aa)

IKVTDYLGSGQFGTVNKG--VWTTPT-AGSV----SVAIKTLNDN-TSEDERVKFLQEAAIMGQ-FHHPNVVKLHGVVTIGHPIMIVLELISGGDLKEYL
.. .. ||.| ||.| ||  . .     ..|     |. |... . ...... .|..|| || . . ||||||..|| .  .|||||.|...||.|..||
VTLGKKLGEGAFGEVYKGRRTLKCKKGKWHVVNKVAVKVKKCKCEDATKEQIKEFMHEARIMRNNYDHPNVVKFYGVCVDEQPIMIVMEFCNGGSLDSYL

NKFKPSPGELVLSSVPSI--LLSFCRQIASGMEYLSRKKFVHRDLAARNILVSA
 | |          . |.  .. .| |.|.|||||  |. .|||.||||.|...
KKNKNK--------TVSDNEKIRMCYQAACGMEYLHSKNCIHRDIAARNCLYHK
Kinase AqueK297.AA Ack 1372-1512 40 6.7e-45 149.4 In-house 1-138 (266) Show / Hide 
Range on Protein: 1372-1512
Range on HMM: 1-138/266
Sequence Identity: 40% (58 aa)

IKVTDYLGSGQFGTVNKGVWTTPTAGSVSVAIKTLNDN--TSEDERVKFLQEAAIMGQFHHPNVVKLHGVVTIGHPI-MIVLELISGGDLKEYLNKFKPS
|..   ||.| || | .|.||.|   ...||.| | .   ..  .   ||.|.||| .  ||..|.|.|||  . |  | | ||  .| | . | |  ..
ITLCEKLGDGCFGVVWRGEWTNPGGKHIQVAVKCLRSDKMQQPNCMDDFLREVAIMHSLDHPHLVRLYGVV-LDQPMLMMVTELAPCGSLLDCLRK-HCR

PGELVLSSVPSILLSFCRQIASGMEYLSRKKFVHRDLAARNILV
.  . .    ..|. ||.|||.|| ||  | ..||||||||||.
TAFFLI----HTLCDFCMQIAMGMRYLEMKRCIHRDLAARNILL
Kinase AqueK297.AA Src 1372-1513 41 3.1e-43 144.69 In-house 1-131 (255) Show / Hide 
Range on Protein: 1372-1513
Range on HMM: 1-131/255
Sequence Identity: 41% (59 aa)

IKVTDYLGSGQFGTVNKGVWTTPTAGSVSVAIKTLNDNTSEDERVKFLQEAAIMGQFHHPNVVKLHGVVTIGHPIMIVLELISGGDLKEYLNKFKPSPGE
||  . ||.|||| | .|.|     |.. ||.|||   |   .   ||||| || .. |...|.|. |.. . || || |. | | | .|| | ..  ..
IKLCRKLGQGQFGEVWMGYW----NGNTKVAVKTLKPGT--MSPEAFLQEAQIMKKLRHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKK-DGEGRH

LVLSSVPSILLSFCRQIASGMEYLSRKKFVHRDLAARNILVS
| |     .|...  |.|.||.||......||||||||.||.
LHL----PQLIDMAAQVAEGMAYLESMNYIHRDLAARNVLVG
Kinase AqueK297.AA InsR 1372-1514 37 1.2e-41 137.62 In-house 1-154 (278) Show / Hide 
Range on Protein: 1372-1514
Range on HMM: 1-154/278
Sequence Identity: 37% (58 aa)

IKVTDYLGSGQFGTVNKG--VWTTPTAGSV--SVAIKTLNDNTSEDERVKFLQEAAIMGQFHHPNVVKLHGVVTIGHPIMIVLELISGGDLKEYLNKFKP
|     .| | ||.|  |      |  ..    .||||.|.| |  ||. ||.|| .| .| . .||.| ||.. | | ..| |.   |||| ||    |
IVLIRECGQGSFGMVYEGIAKGIVPDEEWRFGRCAIKTVNENASMRERIEFLNEASVMKEFNCHHVVRLLGVCSRGQPMYVVMEMMTYGDLKSYLRSRRP

SPG--ELVLS---SVPSI--LLSFCRQIASGMEYLSRKKFVHRDLAARNILVSA
  .  ....    .||.   ...   .|..|| ||  |||||||||.|| .|..
EEEFNNPGCNRNQHVPCLDQMHQMAAEICDGMAYLAAKKFVHRDLACRNCMVNH
Kinase AqueK297.AA TK-Unique 1372-1513 32 1.4e-40 137.69 In-house 1-167 (294) Show / Hide 
Range on Protein: 1372-1513
Range on HMM: 1-167/294
Sequence Identity: 32% (55 aa)

IKVTDYLGSGQFGTVNKGVWTTPT--AGSV-SVAIKTLNDNTSEDERVKFLQEAAIMGQFH-HPNVVKLHGVVT-IGHPIMIVLELISGGDLKEYLNKFK
..| |..|.|.||.| .|  ....   .   .||.|.|.|| .. .. .||.|...| .   |||.|.. |. |  . | ||..| ...|.|  || ...
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR

PS-----------------PGELVLSSVP-SILLSFCRQIASGMEYLSR--KKFVHRDLAARNILVS
|                  | .  ....    |..|. |||.|||||..  ||.|||||.|||.|..
PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLT
Kinase AqueK297.AA ALK 1372-1513 39 6.1e-38 128.56 In-house 1-145 (273) Show / Hide 
Range on Protein: 1372-1513
Range on HMM: 1-145/273
Sequence Identity: 39% (57 aa)

IKVTDYLGSGQFGTVNKGVWTT--PTAGSVSVAIKTLNDNTSEDERVKFLQEAAIMGQFHHPNVVKLHGVVTIGHPIMIVLELISGGDLKEYLNKFKPSP
|.    || | || |  |  .     .    ||.|||    |...   |. ||.|||.| |.|||.. |.     | |||||...|||.| .|    | |
ITLVRALGHGAFGEVYMGQYSHMPGDSVPMQVAMKTLPEDCSQQDEEDFCMEALIMGKFNHQNVVRCIGICFQKQPYMIVLEYMEGGDMKSFLRECRPHP

GELVLSSVP-SILLSFCRQIASGMEYLSRKKFVHRDLAARNILVS
. | .|.   . ||  |. .| |  ||  ..|.||| ||||.| .
ESLQPSQLTMKDLLQCCCDVAQGCHYLEENHFIHRDIAARNCLLT
Kinase AqueK297.AA Ror 1372-1462 37 2.8e-22 80.34 In-house 1-93 (308) Show / Hide 
Range on Protein: 1372-1462
Range on HMM: 1-93/308
Sequence Identity: 37% (35 aa)

IKVTDYLGSGQFGTVNKGVWTTPT--AGSVSVAIKTLNDNTSEDERVKFLQEAAIMGQFHHPNVVKLHGVVTIGHPIMIVLELISGGDLKEYL
...   || .||| | ||  . |       .|||||. .. |  ..  | ||. .| ..||||.|.| ||.|   |   . | .. ||| | |
VRFMEELGECQFGKVYKGHLMGPNFMYHCMAVAIKTCKHDASPAQWQDFRQEIMLMATLHHPNIVCLLGVCTMDQPYCMLFEYMNHGDLHEFL
Kinase AqueK297.AA TyrKc 1372-1528 22 3.3e-15 23.2 SMART 1-280 (280) Show / Hide 
Range on Protein: 1372-1528
Range on HMM: 1-280/280
Sequence Identity: 22% (68 aa)

IKVTDYLGSGQFGTVNKGVWTTPTAGSVSVAIKTLNDNTSEDERVKFLQEAAIMGQF--HHPNVVKLHGVVTIG-------HPIMIVLELISGGDLKEYL
|.  . ||.|.||.| ||.|.      . ||.|.|....    |  |..|| || ..  ||||.|.|.||.| .       .|.|||.|. ..||||.||
ITLGKKLGEGAFGEVYKGTWK------IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYL

NKFKPSPGELVLSSVPSILLSFCRQIASGMEYLSRKKFVHRDLAARNILVSAXX-------------XXV--------LVMC----GVM-----------
 | .|      |.  .. ||||| |||.|||||..|...||||||||.||..                            .     |             
RKHRPK-----LC--MKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPE

----------------------------------------------------------E-------------------------------------L
                                                          .                                     .
CINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase AqueK297.AA Pkinase 1372-1505 25 1.7e-14 52.35 Pfam 1-134 (293) Show / Hide 
Range on Protein: 1372-1505
Range on HMM: 1-134/293
Sequence Identity: 25% (36 aa)

IKVTDYLGSGQFGTVNKGVWTTPTAGSVS-VAIKTLN-DNTSEDERVKFLQ--EAAIMGQFHHPNVVKLHGVVTIGHPIMIVLELISGG----DLKEYLN
...   .||| ||.| |...     |.   ||.|... .........  .   |..||  ..|||.|.|..... .  | .|.|.  ||    ||..|. 
YHIGRKIGSGSFGCVYKCHH----KGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIS

KFKPSPGELVLSSVPSILLSFCRQIASGMEYLSRKKFVHRDL
    . .  ..   .  . ....||..|.||. .....||||
T---WRHGCFY-FSEWECKFYMYQILRGLEYCHSMGIIHRDL
Kinase AqueK297.AA Ror 1487-1512 80 7.2e-13 47.61 In-house 127-152 (308) Show / Hide 
Range on Protein: 1487-1512
Range on HMM: 127-152/308
Sequence Identity: 80% (21 aa)

QIASGMEYLSRKKFVHRDLAARNILV
|||.|||||| . ||||||||||.||
QIAAGMEYLSSHHFVHRDLAARNCLV
Kinase AqueK297.AA S_TKc 1372-1528 16 5.3e-08 -59.59 SMART 1-231 (231) Show / Hide 
Range on Protein: 1372-1528
Range on HMM: 1-231/231
Sequence Identity: 16% (42 aa)

IKVTDYLGSGQFGTVNKGVWTTPTAGSVSVAIKTLNDNTSEDERVKFLQEAAIMGQFHHPNVVKLHGVVTIGHPIMIVLELISG--GDLKEYLNKFKPSP
 .. . .|.| ||.| |....        |||| ..         ....| .|. . ||||.|||..|    . . .|.|...|  |||..|. | .. .
YEILRKIGKGAFGKVYKCRHKK---TGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHG

GELVLSSVPSILLSFCRQIASGMEYLSRKKFVHRDLAARNILVSA----------------------XXXXVLVMCGV----------------------
.  ...  .    ....||....||. .....||||   |||..                           ||   |                       
LRFPFP--E-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDEHIKICDFGLARQLTTFCGTPWYMAPEVL-GYGKCKCDWWSCGCILYEMLCGYPPF

-----------------------------------ME----------L
                                   ..          .
PQMQMMFKKIGSPEAKDFIRKCLQKDPEKRPTAEALQDEWDIKCHPWF