Gene AqueK301 (A.queenslandica)

AqueK301

Species: A.queenslandica
Alias: AqueK301
External Links:
Annotation:

Classification

Group: TK
Family: Eph

Sequence

Name Sequence Type Origin Length Description Download
AqueK301.AA Protein None 179 None Fasta, JSON
AqueK301.kin_dom Protein Kinase Domain None 166 None Fasta, JSON

Protein domain

Protein domains of AqueK301.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Pkinase_Tyr AqueK301.AA Pkinase_Tyr 1-172 43 5.3e-91 308.83 Pfam 57-239 (270) Show / Hide 
Range on Protein: 1-172
Range on HMM: 57-239/270
Sequence Identity: 43% (80 aa)

MGQF-HHDNVVVLYGVIS-RIDP--VMIVMEYLQNGSLDRYLQKN---LDKISHERLAKMSYGVAKGMKYLSSIGFVHRDLAARNILVANDETCKVADFG
| |. ||.|.| ||||.. . .|  ..||||| ..|.|. ||.|.    .......| .|.. .|||| ||.|....||||||||.||... ..|..|||
MKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFG

LAREM-VENEY-DVQKGGRIPVRWTAPEAISHRSFTTASDVWSYGVLLWETFSFGETP-YDGWDNATIFQRL-ENGERLHPPR
||| .  . .|  ...||..|..|.|||.|... |||.|||||.|||.|| |..||.| | |..|. ..... |.|.|. .|.
LARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPE
Kinase AqueK301.AA Eph 1-172 51 5.7e-85 285.38 In-house 58-233 (264) Show / Hide 
Range on Protein: 1-172
Range on HMM: 58-233/264
Sequence Identity: 51% (92 aa)

MGQFHHDNVVVLYGVISRIDPVMIVMEYLQNGSLDRYLQKNLDKISHERLAKMSYGVAKGMKYLSSIGFVHRDLAARNILVANDETCKVADFGLAR----
|||| | |.. | ||...  ||||| ||  ||||| .| .. ....  .|  | .|.| ||||||. ..||||||||||||  .  |||.|||| |    
MGQFDHPNIIRLEGVVTKSRPVMIVTEYMENGSLDSFLRQHDGQFTVIQLVGMLRGIASGMKYLSDMNYVHRDLAARNILVNSNLVCKVSDFGLSRVLED

EM-VENEYDVQKGGRIPVRWTAPEAISHRSFTTASDVWSYGVLLWETFSFGETPYDGWDNATIFQRLENGERLHPPR
.  || .|  . ||.||.||||||||..| ||.||||||||...||  |.|| ||  . |  . .  | | || ||.
DPSVEATYTTR-GGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEQGYRLPPPM
Kinase AqueK301.AA TK 1-172 23 1.9e-76 255.61 In-house 92-439 (486) Show / Hide 
Range on Protein: 1-172
Range on HMM: 92-439/486
Sequence Identity: 23% (83 aa)

MGQFH-----HDNVVVLYGVISRI------------DPVMIVMEYLQNGS----LDRYLQKNLDK-----------------------------------
| ...     |.|.| ||||...              |.|||||| ..|.    |. ||.|. .|                                   
MKMMCHSLGHHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESN

----------------------------------------ISHERLAKMSYGVAKGMKYLSSI------GFVHRDLAARNILVANDET-----------C
                                        .. ..|  |.. .|.|| ||.|       .||||||||||.||... .           |
SPCPEEQDYDDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVC

KVADFG--------LAREM-VENEYDVQK------------------------GGRIPVRWTAPEAISHRS---------FTTASDVWSYGVLLWETFSF
|.||||        |||..  . .| ...                        ||..|.||.|||.. .|          |||.|||||.|||.|| |..
KIADFGLSRQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTY

G-ETPYDGWDN---------ATIFQRLEN------------GERLHPPR
| |..| |..|         . ....|..            |.|. .|.
GQEPYYGGMSNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQ
Kinase AqueK301.AA Src 1-168 44 6.2e-74 250.57 In-house 48-219 (255) Show / Hide 
Range on Protein: 1-168
Range on HMM: 48-219/255
Sequence Identity: 44% (77 aa)

MGQFHHDNVVVLYGVISRIDPVMIVMEYLQNGSLDRYLQ--KNLDKISHERLAKMSYGVAKGMKYLSSIGFVHRDLAARNILVANDETCKVADFGLAREM
| .. |...| || | |. .|. || || ..|||  ||.  .   ... ..|  |.  ||.||.||.|  ..||||||||.|| ..  |||||||||| .
MKKLRHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKKDGEGRHLHLPQLIDMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLARLI

V--ENEYDVQKGGRIPVRWTAPEAISHRSFTTASDVWSYGVLLWETFSFGETPYDGWDNATIFQRLENGERL
   ..||  ..| ..|..|||||||....||. |||||.|.||.| ...| .|| |..|.  .|..|.| |.
KEDDDEYCARHGAKFPIKWTAPEAINYGRFTIKSDVWSFGILLTEIVTYGRVPYPGMTNHEVLQQVERGYRM
Kinase AqueK301.AA UTK 1-172 39 1.3e-68 233.85 In-house 63-263 (296) Show / Hide 
Range on Protein: 1-172
Range on HMM: 63-263/296
Sequence Identity: 39% (80 aa)

MGQFH-HDNVVVLYGVISRIDPVMIVMEYLQNGSLDRYLQKNLDKIS-------HERLAKMSYGVAKGMKYLSSIGFVHRDLAARNILVAND-------E
|.||| | ||. |.|| ..  | |||.|| .||.|. ||... ..          ... .|.. .| || ||.| |||||||||||.||. .       .
MKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSYLRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMM

TCKVADFG---LAREMV---------ENEYDVQKG-GRIPVRWTAPEAISHR-SFTTASDVWSYGVLLWETFSFGETPYDGWDNATIFQRLENGERLHPP
.||.||||   ..|..          | .|  . . .|.|.||.||||. |.  |||.|||||.||..||....| .|| |. |. ......|| |...|
VCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQDRWPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMP

R
.
C
Kinase AqueK301.AA Fer 1-171 37 5.3e-66 223.75 In-house 62-249 (283) Show / Hide 
Range on Protein: 1-171
Range on HMM: 62-249/283
Sequence Identity: 37% (70 aa)

MGQ-FHHDNVVVLYGVISRIDPVMIVMEYLQNGSLDRYLQKNLDK-ISHERLAKMSYGVAKGMKYLSSIGFVHRDLAARNILVANDET---CKVADFGLA
| . . |.||| .|||..   |.|||||.  .|||| ||.|| .| .|   . .|.|..|.||.|| | . .|||.||||.|. .|..   ||..|||..
MRNNYDHPNVVKFYGVCVDEQPIMIVMEFCNGGSLDSYLKKNKNKTVSDNEKIRMCYQAACGMEYLHSKNCIHRDIAARNCLYHKDKVKKKCKISDFGMS

REMVENEYDVQKG---GRIPVRWTAPEAISHRSFTTASDVWSYGVLLWETFSFGETPYDG---------WDNATIFQRLENGERLHPP
|.  ...|| ...    ..|.||.|||... . .....||||.||..|| |. |..|| |         ... .. .  ..| .. .|
RQCSDYGYDYKMKEKACKVPIRWLAPETWQTGIYSPKTDVWSFGVMCWEIFTNGAEPYPGQPHGMKMTNVKKQARKWIIKKGYMMPMP
Kinase AqueK301.AA RTKC 1-155 46 1.3e-63 208.82 In-house 55-213 (261) Show / Hide 
Range on Protein: 1-155
Range on HMM: 55-213/261
Sequence Identity: 46% (74 aa)

MGQFHHDNVVVLYGVISRIDPVMIVMEYLQNGSLDRYLQKNLDKISHERLAKMSYGVAKGMKYLSSIGFVHRDLAARNILVANDETCKVADFGLAREM--
| || | ||| | ||..   |. .|.|.. .|||  || .|  ... .  .  .| .| ||    | ||.|||.||||.|.. | ||||||||||||   
MAQFEHPNVVHLIGVVTVGKPILVVLEFCERGSLKSYLMNNP-DCTEHQKVRFCYQCASGMEHIHSFGFIHRDVAARNVLLSSDLTCKVADFGLARESPC

---VENEYDVQKGGRIPVRWTAPEAISHRSFTTASDVWSYGVLLWETFSFGETPYDGWDN
    .  |    .| .|||||||||   | |. .||||. |.|. | .  .| ||||| |
NDDSHEAYYRSRSGNLPVRWTAPEALDDRKFSEKSDVWAFGILMYEIYTKAEMPYDGWSN
Kinase AqueK301.AA TK-Unique 6-168 36 1.2e-62 214.39 In-house 63-258 (294) Show / Hide 
Range on Protein: 6-168
Range on HMM: 63-258/294
Sequence Identity: 36% (72 aa)

HDNVVVLYGVISRID-PVMIVMEYLQNGSLDRYLQKNLDK-------------------------ISHERLAKMSYGVAKGMKYLSS--IGFVHRDLAAR
| |.| ..|.  . | |.||.|||...|.|. ||... ..                         || ..|.   ...|.||.||.|   ..|||||.||
HPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCRPAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCAR

NILVANDETCKVADFGLAR-EMVENEYDVQKG-GRIPVRWTAPEAIS--HRSF-TTASDVWSYGVLLWETFSFGETPYDGWDNATIFQRLENGERL
|.|...| .||..|||.|| .. ...|. ... ||||.|| |||...  |. . || |||||.|||.|| |..|..|| | ... | .....| |.
NVLLTEDKVCKICDFGMARDVYTNGVYSMMCSQGRIPIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYRM
Kinase AqueK301.AA Src-Unclassified 1-168 37 2.3e-58 198.75 In-house 59-246 (284) Show / Hide 
Range on Protein: 1-168
Range on HMM: 59-246/284
Sequence Identity: 37% (71 aa)

MGQFHHDNVVVLYGVISRIDPVMIVMEYLQNGSLDRYLQKNLDKISH-ERL------------AKMSYGVAKGMKYLSSIGFVHRDLAARNILVANDE--
| .. | |.| ||.| |.  |  |. ||  ||||  .|..   .  | . .            . ..  || || ||.| . |||||||||.|.      
MKKCRHQNLVHLYAVCSQEEPYYIITEYMINGSLLQWLREGGGQYLHIQDMSEETGRKNVLIGVDIAAQVASGMMYLESKKYVHRDLAARNVLIGHNNSN

---TCKVADFGLA--REMVENEYDVQKGGRIPVRWTAPEAISHRSFTTASDVWSYGVLLWETFSFGETPYDGWDNATIFQRLENGERL
     ||.|||||  . | . .|   .| . |. |.|||..    |.. |||||||.|||| .  | ||| |..| .    .| | |.
GVPVVKVCDFGLARKKLMQDDNYCMRTGAMFPWKWMAPECFIYGNFSIKSDVWSYGILLWEIMTKGQTPYPGMHNREVLEHVERGYRM
Kinase AqueK301.AA TyrKc 1-176 28 5.3e-58 199.93 SMART 1-280 (280) Show / Hide 
Range on Protein: 1-176
Range on HMM: 1-280/280
Sequence Identity: 28% (79 aa)

M-------------------------------------------GQF--HHDNVVVLYGVISRI-------DPVMIVMEYLQNGSLDRYLQKNLDKISHE
                                             ..  ||.|.| ||||..         .|.||||||  .|.|. ||.|. .|....
ITLGKKLGEGAFGEVYKGTWKIQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKLCMK

RLAKMSYGVAKGMKYLSSIGFVHRDLAARNILVANDETCKVADFGLAREMVEN-------EYDVQK---GGR--IPVRWTAPEAISHRSFTTASDVWSYG
 | .... .|.|| ||.| ...||||||||.||... |.|..||||.|.  .        .| ..|   ||.  .|.||.|||.| .. |||.|||||.|
DLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDVWSFG

VLLWETFSFGETPYDG-----WDNATIFQRLENGERLHPPRV---------------------------RP--------L
|..|| |..|..|| |      .|. .......|.|. .|                             ||        .
VCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase AqueK301.AA Frk 1-171 42 7.2e-57 195.24 In-house 48-224 (260) Show / Hide 
Range on Protein: 1-171
Range on HMM: 48-224/260
Sequence Identity: 42% (76 aa)

MGQFHHDNVVVLYGVISRIDPVMIVMEYLQNGSLDRYLQ---KNLDKISHERLAKMSYGVAKGMKYLSSIGFVHRDLAARNILVANDETCKVADFGLAR-
| .  |  .. || |  . .|..|. | ...|||  |||   ..  ..  . |  |.  || || || |  ..||||||||.|| ..  ||.||||||| 
MKKLRHPKLIQLYAVCTVEEPIYIITELMRHGSLQEYLQAINDKGRQCQMQQLVDMAAQVAAGMAYLESQNYIHRDLAARNVLVGEHNICKIADFGLARV

EMVENE--YDVQKGGRIPVRWTAPEAISHRSFTTASDVWSYGVLLWETFSFGETPYDGWDNATIFQRLENGERLHPP
 |..||  |. . | |.|..||||||.   .||. |||||.|.|| |   .|  || |  || . | ...| |.  |
LMKDNEDIYESRHGARFPIKWTAPEAANYNKFTIKSDVWSFGILLTEIITYGRMPYPGMTNAEVLQMVDHGYRMPQP
Kinase AqueK301.AA Csk 1-150 49 1.1e-55 188.55 In-house 48-198 (251) Show / Hide 
Range on Protein: 1-150
Range on HMM: 48-198/251
Sequence Identity: 49% (75 aa)

MGQFHHDNVVVLYGVISRID-PVMIVMEYLQNGSLDRYLQ-KNLDKISHERLAKMSYGVAKGMKYLSSIGFVHRDLAARNILVANDETCKVADFGLAREM
| |  |.| | | |||      . |||||. .|.|  ||       |. . | | .. |..|| || .  |||||||||||||  |   || |||||.| 
MTQLRHPNLVQLIGVILHQKNHLYIVMEYMSKGNLVDYLRSRGRHVITRRQLLKFAMDVCEGMCYLEQKKFVHRDLAARNILVSEDCVAKVSDFGLAKEE

VENEYDVQKGGRIPVRWTAPEAISHRSFTTASDVWSYGVLLWETFSFGETPY
  .  |   .|..|. ||||||  |  |.| |||||.|.|||| .|||  ||
CSQQDDS-TSGKFPIKWTAPEALRHKKFSTKSDVWSFGILLWEIYSFGRVPY
Kinase AqueK301.AA Pkinase 1-179 25 4.3e-30 107.5 Pfam 54-244 (293) Show / Hide 
Range on Protein: 1-179
Range on HMM: 54-244/293
Sequence Identity: 25% (49 aa)

MGQFHHDNVVVLYGVISRIDPVMIVMEYLQNG----SLDRYLQ-KNLDKI--SHERLAKMSYGVAKGMKYLSSIGFVHRDLAARNILVANDETC----KV
|  ..|.|.| ||..  . | . .||||...|    .| .|.. ..  ..  | . . .. | ...|..|. | |..||||   |||. |. ..    |.
MKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKI

ADFGLAREMVENEYDVQKGGRIPVRWTAPEAIS-HRSFTTASDVWSYGVLLWETFSFGETPYDGW----DNATIFQRLENGERLHPPRVRPLHVP
.|||||. . .  .   ..     .. ||| |  ..  ....|.||.|..|.| .. |..|..|     . ..  |....  .  ... .|   .
CDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLC-GRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCS
Kinase AqueK301.AA S_TKc 2-173 21 5.2e-12 -0.76 SMART 10-231 (231) Show / Hide 
Range on Protein: 2-173
Range on HMM: 10-231/231
Sequence Identity: 21% (52 aa)

GQF---------------------------------HHDNVVVLYGVISRIDPVMIVMEYLQN--GSLDRYLQKNLDK-----ISHERLAKMSYGVAKGM
| |                                 ||.|.| ||.|.   | . .||||. .  |.| .|..|.  .     ..  . ... | .....
GAFGKVYKCRHKKTGRIVAIKIIKEHIRREIQILKKHHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCAL

KYLSSIGFVHRDLAARNILVANDETCKVADFGLAREMVENEYDVQKGGRIPVRWTAPEAISHRSFTT-ASDVWSYGVLLWETFSFGETPYDGWDNATIFQ
.|. | |..||||   |||. .  . |..||||||..        .       . ||| .   .... ..|.|| |..|.| .. |..|..  . ...|.
EYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLC-GYPPFP--QMQMMFK

---------------------RLENGERLH-------PPRV
                     |.   | |.        | .
KIGSPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF