Gene AqueK303 (A.queenslandica)
AqueK303
Species: A.queenslandica
Alias: AqueK303
External Links:
Annotation:
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| AqueK303.AA | Protein | None | 915 | None | Fasta, JSON |
| AqueK303.kin_dom | Protein Kinase Domain | None | 206 | None | Fasta, JSON |
Protein domains of AqueK303.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | AqueK303.AA | Pkinase_Tyr | 683-876 | 43 | 4.4e-92 | 312.48 | Pfam | 80-270 (270) | Show / Hide |
Range on Protein: 683-876 Range on HMM: 80-270/270 Sequence Identity: 43% (86 aa) NELIMIVLELISGGDLKEYLNKFKPSPGELVLSSVPSILLSFCRQIASGMEYLSRKKFVHRDLAARNILVSDEGTGICKIGDFGMSRDL-KDESY-YISQ | |.||.|. .|||..|| | . | . .. ||..|.|||.|||||..|...||||||||.||.. ....||.|||..||. .|. | . .. N-QIYIVMEYMPHGDLLDYLRKHR----EDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTE--NNVVKICDFGLARDIYNDDYYYRKRG AKKIPIKWTAPEALHYKKYSSASDVWSYGAVMYEIWSLGHKP-FEIYTNQECIRLV-DSGYRLPPPPGCPKPMYKLMMKCWNPDTHDRPSFSDISSSL |.||||.|||...|.|....|||||.| .|.|| ..| .| .. .|.| .... ..|||.|.|..||...|.||..||..| |||.||.| . | GGKLPIKWMAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL |
|||||||||
| Kinase | AqueK303.AA | TK | 681-876 | 24 | 8.3e-87 | 290.96 | In-house | 125-486 (486) | Show / Hide |
Range on Protein: 681-876
Range on HMM: 125-486/486
Sequence Identity: 24% (90 aa)
LMNELIMIVLELISGGD----LKEYLNKFKPSPGELVLSSV------------------------------------------------PSILLS-----
. .| .|||.|. ..|| |..|| | .| . .. . ||.
VHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDYDDDLIKDHPPPLTTKDLLQMAWQW
--------------FCRQIASGMEYLSRK------KFVHRDLAARNILVSDEGT---------GICKIGDFGMS--------RDL-KDESYYISQ-----
.|.|||.|||||..| .||||||||||.||..... .|||.|||.| ||. .|. || ..
CLTCKHQLTMHQLLMCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQGSGVLARDIYSDDDYYRKSSYGTG
-------------------AKKIPIKWTAPEALH---------YKKYSSASDVWSYGAVMYEIWSLG-HKPFEIYTN---------QECIRLVDSG----
|.||.|.|||.| |.|....|||||.| .|.||...| . . .| || .... .|
RPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMSNQDVWKDGDNQEVMEYLRRGGRLC
----------YRLPPPPGCP--------------KPMYKLMMKCWNPDTHDRPSFSDISSSL
.|.|.||.|| . .| ||..||..| |||.||.. . |
RSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
|
|||||||||
| Kinase | AqueK303.AA | UTK | 684-876 | 39 | 2.6e-81 | 276.44 | In-house | 83-296 (296) | Show / Hide |
Range on Protein: 684-876
Range on HMM: 83-296/296
Sequence Identity: 39% (85 aa)
ELIMIVLELISGGDLKEYLNKFKPSPGELVLSSVPSILLSFCRQIASGMEYLSRKKFVHRDLAARNILVSDEG-----TGICKIGDFG---MSRDLKD--
| .|||.|. ..||| || . .|.|.. .. .|.....||.||.||....||||||||||.|| . . .|||.||| |||....
EPWMIVTEYMENGDLRSYLRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFH
------ES-YYISQ-AKKIPIKWTAPEALHYK-KYSSASDVWSYGAVMYEIWSLGHKPFEIYTNQECIRLVDSG--YRLPPPPGCPKPMYKLMMKCWNPD
|| || .| ....||.|.||||| . .....|||||.| |..|||. | .|.. ..|.. . | | ||.|.|..|| |.|.||..||..|
FSNRYWESYYYMAQHQDRWPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYD
THDRPSFSDISSSL
.||.| |. . .
PQERPDFEDLVQQM
|
|||||||||
| Kinase | AqueK303.AA | Eph | 728-876 | 52 | 1.5e-74 | 249.85 | In-house | 114-264 (264) | Show / Hide |
Range on Protein: 728-876 Range on HMM: 114-264/264 Sequence Identity: 52% (80 aa) IASGMEYLSRKKFVHRDLAARNILVSDEGTGICKIGDFGMSRDLKDES----YYISQAKKIPIKWTAPEALHYKKYSSASDVWSYGAVMYEIWSLGHKPF ||||| ||| .||||||||||||. . .||. |||.|| |.|.. | .. ||||.||||||. |.|..||||||||| || |. | | .|. IASGMKYLSDMNYVHRDLAARNILVNSN--LVCKVSDFGLSRVLEDDPSVEATYTTRGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPY EIYTNQECIRLVDSGYRLPPPPGCPKPMYKLMMKCWNPDTHDRPSFSDISSSL .||. | .. |||||||..||.....||..|| | ..|| |..| | | WDMSNQDVIKAIEQGYRLPPPMDCPEALHQLMLDCWQKDRNHRPHFQQIVSIL |
|||||||||
| TyrKc | AqueK303.AA | TyrKc | 646-876 | 34 | 6.5e-74 | 252.78 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 646-876
Range on HMM: 1-280/280
Sequence Identity: 34% (101 aa)
TEFSNEL----YGLLEEATLYVP----TAKERSGEESEEIYS--TLMNEL--------------------------IMIVLELISGGDLKEYLNKFKPSP
.. .| .| ..|.... . || . |.... .| .| .|||.|. ..||||.|| | .|
ITLGKKLGEGAFGEVYKGTWKIQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK-
GELVLSSVPSILLSFCRQIASGMEYLSRKKFVHRDLAARNILVSDEGTGICKIGDFGMSRDLKDE-------SYYISQ---AKK--IPIKWTAPEALHYK
|. .. ||||| |||.|||||..|...||||||||.||.... ..||.|||.|||..|. .|| .. .| .||.|.|||.. |.
----LC--MKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH--TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYG
KYSSASDVWSYGAVMYEIWSLGHKPFEI-----YTNQECIRLVDSGYRLPPPPG--------CPKPMYKLMMKCWNPDTHDRPSFSDISSSL
|....|||||.| .|.|| ..| .| . .||| |..|..|||.|.|| ||. ||..| .||. | .|||.||.| . .
KFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
|
|||||||||
| Kinase | AqueK303.AA | Src | 686-876 | 40 | 3.8e-72 | 244.41 | In-house | 69-255 (255) | Show / Hide |
Range on Protein: 686-876 Range on HMM: 69-255/255 Sequence Identity: 40% (79 aa) IMIVLELISGGDLKEYLNKFKPSPGELVLSSVPSILLSFCRQIASGMEYLSRKKFVHRDLAARNILVSDEGTGICKIGDFGMSRDLK--DESYYISQAKK | || |. | | | .|| | .. ..| | .|... |.|.||.||......||||||||.||... .||..||| | .| |. | .. | IYIVTEYMSHGSLLDYLKK-DGEGRHLHL----PQLIDMAAQVAEGMAYLESMNYIHRDLAARNVLVGENN--VCKVADFGLARLIKEDDDEYCARHGAK IPIKWTAPEALHYKKYSSASDVWSYGAVMYEIWSLGHKPFEIYTNQECIRLVDSGYRLPPPPGCPKPMYK-LMMKCWNPDTHDRPSFSDISSSL .|||||||||..| ... |||||.| ..|| . | | . ||.| .. |. |||.| |..||. .|. .|..||. | .|| | . . | FPIKWTAPEAINYGRFTIKSDVWSFGILLTEIVTYGRVPYPGMTNHEVLQQVERGYRMPCPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL |
|||||||||
| Kinase | AqueK303.AA | Fer | 686-877 | 37 | 9.6e-71 | 240.13 | In-house | 84-283 (283) | Show / Hide |
Range on Protein: 686-877 Range on HMM: 84-283/283 Sequence Identity: 37% (77 aa) IMIVLELISGGDLKEYLNKFKPSPGELVLSSVPSI--LLSFCRQIASGMEYLSRKKFVHRDLAARNILVSDEGTGI-CKIGDFGMSRDLKDESYYIS--- ||||.|...||.|..|| | | . |. .. .| |.|.||||| |. .|||.||||.|...... . ||| ||||||...|. | . IMIVMEFCNGGSLDSYLKKNKNK--------TVSDNEKIRMCYQAACGMEYLHSKNCIHRDIAARNCLYHKDKVKKKCKISDFGMSRQCSDYGYDYKMKE QAKKIPIKWTAPEALHYKKYSSASDVWSYGAVMYEIWSLGHKPFEI------YTNQ--ECIRL-VDSGYRLPPPPGCPKPMYKLMM-KCWNPDTHDRPSF |.|.||.|.|||.. .. ||...||||.| ...|| . | .|.. ||. .... ...||..|.|...|......|| .||. |. |||.. KACKVPIRWLAPETWQTGIYSPKTDVWSFGVMCWEIFTNGAEPYPGQPHGMKMTNVKKQARKWIIKKGYMMPMPNHMPPEIMQIMMKQCWQKDPEDRPTM SDISSSLS ..| | KEICQKLK |
|||||||||
| Kinase | AqueK303.AA | TK-Unique | 684-876 | 36 | 6.3e-68 | 231.98 | In-house | 78-294 (294) | Show / Hide |
Range on Protein: 684-876 Range on HMM: 78-294/294 Sequence Identity: 36% (80 aa) ELIMIVLELISGGDLKEYLNKFKPS-----------------PGELVLSSVP-SILLSFCRQIASGMEYLSR--KKFVHRDLAARNILVSDEGTGICKIG | ||..| ...|.| || ...| | . .... |..|. |||.|||||.. ||.|||||.|||.|... ..|||. EPWMIIMEYCPCGNLQHYLRTCRPAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTE--DKVCKIC DFGMSRDLKDESYYISQAK--KIPIKWTAPEALH--YKKY-SSASDVWSYGAVMYEIWSLGHKPFEIYTNQECIRLVDSGYRLPPPPGC-PKPMYKLMMK ||||.||. .. |... . .|||.| |||.| .. | .. |||||.| .|.|| .|| |. . . . .... |||.| |..| .. ||.|| DFGMARDVYTNGVYSMMCSQGRIPIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYRMPQPEHCCSHEMYNLMKS CWNPDTHDRPSFSDISSSL ||. . ..||||..| . | CWQWEPEERPSFRQIKHRL |
|||||||||
| Kinase | AqueK303.AA | SRM | 688-877 | 43 | 2e-67 | 224.52 | In-house | 72-253 (253) | Show / Hide |
Range on Protein: 688-877 Range on HMM: 72-253/253 Sequence Identity: 43% (83 aa) IVLELISGGDLKEYLNKFKPSPGELVLSSVPSILLSFCRQIASGMEYLSRKKFVHRDLAARNILVSDEGTGICKIGDFGMSRDLKDESYYISQAKKIPIK |. || | | .|| .. | .|. . || | |.| || || ....||||||||.|| |. . ||.||||. | .|| | | .||.| IITELMRKGNLQQYLR----DSDEKALPIPH--LLDFACQVAEGMCYLEEQNYIHRDLAARNVLVGDNNL--CKVGDFGLARLIKDDIYSPSHDHNIPYK WTAPEALHYKKYSSASDVWSYGAVMYEIWSLGHKPFEIYTNQECIRLVDSGYRLPPPPGCPKPMYKLMMKCWNPDTHDRPSFSDISSSLS ||||||. | || |||||.| ..|. . | |.. || | . .| |||.| | || .|||..|| | .||.| | |. WTAPEAANYRHYSQKSDVWSFGILLHEMFTYGQCPYPGMTNHETFQQIDRGYRMPCPAECPPEVHKLMLECWCRDPEQRPCFKDLREKLT |
|||||||||
| Kinase | AqueK303.AA | Syk | 684-870 | 41 | 1.4e-62 | 214.21 | In-house | 77-257 (257) | Show / Hide |
Range on Protein: 684-870 Range on HMM: 77-257/257 Sequence Identity: 41% (79 aa) ELIMIVLELISGGDLKEYLNKFKPSPGELVLSSVPSILLSFCRQIASGMEYLSRKKFVHRDLAARNILVSDEGTGICKIGDFGMSRDLK-DESYYISQAK | | |.|. ..| . || . . | ..| .. . |.|.|| || |.||||||||||.| .. . || |||||. | |..|| .. EMMMMVMEMAELGPMHKYLQQHR---HEITANNVLELWHT---QVAMGMCYLEEKHFVHRDLAARNVLLVNR--HYAKISDFGMSKALGADSQYYQATTH -KIPIKWTAPEALHYKKYSSASDVWSYGAVMYEIWSLGHKPFEIYTNQECIRLVDSGYRLPPPPGCPKPMYKLMMKCWNPDTHDRPSFS | |.|| ||| | | |..|||||.| | | |.| || ..|| . ....| |.. |.|||. || || ||| . ||| |. GKWPVKWYAPECIYYYKFSHKSDVWSFGVTMWEMFSYGQKPYGEMKGQEVMKFIENGHRMNCPNGCPQEMYQLMNKCWIYKWCDRPTFV |
|||||||||
| Kinase | AqueK303.AA | Tec | 686-878 | 39 | 3.6e-62 | 212.84 | In-house | 69-254 (254) | Show / Hide |
Range on Protein: 686-878 Range on HMM: 69-254/254 Sequence Identity: 39% (76 aa) IMIVLELISGGDLKEYLNKFKPSPGELVLSSVPSILLSFCRQIASGMEYLSRKKFVHRDLAARNILVSDEGTGICKIGDFGMSRDLKDESYYISQAKKIP | || | .. | | .|| . | ... .|||. | .. ||.|| |..|.|||||||| ||.|. .. |. ||||.| | | | | | IYIVTEYMEHGCLLNYLREHK-----HHFQKNMAILLEMCQDVCEGMAYLERHCFIHRDLAARNCLVGDQ--CVVKVSDFGMTRYVLDDQYTSSVGTKFP IKWTAPEALHYKKYSSASDVWSYGAVMYEIWSLGHKPFEIYTNQECIRLVDSGYRLPPPPGCPKPMYKLMMKCWNPDTHDRPSFSDISSSLSS .|| .|| .|| .||| ||||..| | |..|.| |.| ..| | . | |.|| | |.. .|. | .|| .||.|.. ... VKWCPPEVFHYSRYSSKSDVWAFGVLMWEVFSCGKMPYENMSNSEVVEHVSQGHRLYRPHLCSMHIYQIMYHCWHEKPEERPTFQQLLRQITE |
|||||||||
| Kinase | AqueK303.AA | Ack | 686-876 | 39 | 5.6e-62 | 207.85 | In-house | 77-266 (266) | Show / Hide |
Range on Protein: 686-876 Range on HMM: 77-266/266 Sequence Identity: 39% (78 aa) IMIVLELISGGDLKEYLNKFKPSPGELVLSSVPSILLSFCRQIASGMEYLSRKKFVHRDLAARNILV-SDEGTGICKIGDFGMSRDLK-DESYYISQAKK .| | || .| | . | | ... . . ..|. ||.|||.|| || | ..||||||||||. ||. ||.||| .| |. | || .. .. LMMVTELAPCGSLLDCLRK-HCRTAFFLI----HTLCDFCMQIAMGMRYLEMKRCIHRDLAARNILLFSDD--RKVKICDFGLMRALGQNEDYYRMEFHR ---IPIKWTAPEALHYKKYSSASDVWSYGAVMYEIWSLGHKPFEIYTNQECIRLVD-SGYRLPPPPGCPKPMYKLMMKCWNPDTHDRPSFSDISSSL .|. | |||.| ... |.|||||..| . | | | .|. .. . ....| | ||| |. ||. |..||.|| .. |||.||.| | NLKVPFAWCAPECLRHRQFSHASDVWMFGVTLWEMFSYGEEPWAGCNGYQILQKIDKEGERLPRPDCCPEDIYQMMMQCWQHHPADRPTFSAIRDQL |
|||||||||
| Kinase | AqueK303.AA | Pkinase | 688-876 | 20 | 8.5e-20 | 71.08 | Pfam | 77-293 (293) | Show / Hide |
Range on Protein: 688-876 Range on HMM: 77-293/293 Sequence Identity: 20% (47 aa) IVLELISGG----DLKEYLNKFKPSPGELVLSSVPSILLSFCRQIASGMEYLSRKKFVHRDLAARNILVSDEGTGIC----KIGDFGMSRDLKDESYYIS .|.|. || ||..|. . . .. . . ....||..|.||. .....|||| |||.. .| . ||.||| .. .. | . MVMEYCEGGLYVMDLFDYIST---WRHGCFY-FSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID--NNGHIDACVKICDFGLAKQFD---Y-NN QAKKIP---IKWTAPEALH-YKKYSSASDVWSYGAVMYEIWSLGHKPFEIY------TNQECIRLVDS-GYRLPPPPGCP-------------------K . . . . . ||| . ...|....|.||.| ..|| . |. || . ...|... . .. . | |. . S-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLC-GRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSE PMYKLMMKCWNPDTHDRPSFSDISSS--L .. ... .|...| ..||.. .| . . ECKDFIKWCLCKDPKKRPTAEQILQHPWF |
|||||||||
| S_TKc | AqueK303.AA | S_TKc | 612-877 | 18 | 1.8e-14 | 35.16 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 612-877 Range on HMM: 1-231/231 Sequence Identity: 18% (51 aa) LNVSNP----TYGAPENGIGASSAYEVPIVTINRKQENTEFSNELYGLLEEATLYVPTAKERSGEESEEIYSTLMNELIMIVLELISG--GDLKEYLNKF . .. ..| .. .. .| | |. .. | . . ... . . . .|.|...| |||..|. | YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------------EHIRREIQILKK--HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKR KPSPGELVLSSVPSILLSFCRQIASGMEYLSRKKFVHRDLAARNILVSDEGTGICKIGDFGMSRDLKDESYYISQAKKIPIKWTAPEALHYKKYSS-ASD .. .. ... . ....||....||. .....|||| |||... ||.|||..| | . ||| | .|. ..| GRHGLRFPFP--E-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE----HIKICDFGLARQL--------TTFCGTPWYMAPEVL---GYGKCKCD VWSYGAVMYEIWSLGHKPFEIYTNQECIRLVDSGYRLPPPPGCPKPMYKLMMKCWNPDTHDRPSFSDISS--------SLS .|| | ..|| . | ||. . |. .... .... ...||.. | .||. .. WWSCGCILYEMLC-GYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
|||||||||