Gene AqueK350 (A.queenslandica)

AqueK350

Species: A.queenslandica
Alias: AqueK350
External Links:
Annotation:

Classification

Group: TK
Family: Met

Sequence

Name Sequence Type Origin Length Description Download
AqueK350.AA Protein None 559 None Fasta, JSON
AqueK350.kin_dom Protein Kinase Domain None 130 None Fasta, JSON

Protein domain

Protein domains of AqueK350.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
SR AqueK350.AA SR 24-100 38 6.5e-19 70.08 SMART 1-118 (118) Show / Hide 
Range on Protein: 24-100
Range on HMM: 1-118/118
Sequence Identity: 38% (45 aa)

IQLIGGSHDWEGRVEVCNNG----LWGTVCDNNWDSTDA-----------AVGAV----------------IHLDNVQCLGTEQLLTNCTH--STAHN--
. | ||..  ||||||  ||     ||||||.||| .||           || |.                |..|||.| |||. |..|.|     ||  
VRLVGGNNPCEGRVEVYHNGGGQGQWGTVCDDNWDIRDANVVCRQLGCGGAVSASQTLPATWAHFGQGSGPIWMDNVRCTGTETSLWDCPHWGWGQHNNC

CGH------SKDAGVTCH
|.|      . ||||.| 
CSHNHHRNRQEDAGVVCS
SRCR AqueK350.AA SRCR 27-60 59 4.3e-13 45.8 Pfam 1-37 (112) Show / Hide 
Range on Protein: 27-60
Range on HMM: 1-37/112
Sequence Identity: 59% (22 aa)

IGGSHDWEGRVEVCN-NGLWGTVCDN-N-WDSTDAAV
.|||.  ||||||.  || ||||||. . || .|| |
VGGSSPCEGRVEVRYHNGQWGTVCDDDGNWDMRDAHV
SRCR AqueK350.AA SRCR 64-100 43 1.3e-12 44.16 Pfam 69-112 (112) Show / Hide 
Range on Protein: 64-100
Range on HMM: 69-112/112
Sequence Identity: 43% (19 aa)

IHLDNVQCLGTEQLLTNC--THSTA--HN--CGHS-KDAGVTCH
|..|||.| |.|. |..|  ....   ||  |.||  ||||.| 
IWMDNVRCHGNETSLWQCPHSPWGWHRHNPMCSHSREDAGVICS
SRCR AqueK350.AA SRCR 110-143 59 9.3e-17 58.1 Pfam 1-37 (112) Show / Hide 
Range on Protein: 110-143
Range on HMM: 1-37/112
Sequence Identity: 59% (22 aa)

VNGSNSNEGRVELCH-NGRWGTVCDD-S-WDNTDASV
|.||...|||||... ||.||||||| . ||..||.|
VGGSSPCEGRVEVRYHNGQWGTVCDDDGNWDMRDAHV
SR AqueK350.AA SR 107-167 28 1.2e-08 31.42 SMART 1-118 (118) Show / Hide 
Range on Protein: 107-167
Range on HMM: 1-118/118
Sequence Identity: 28% (34 aa)

VRLVNGSNSNEGRVELCHNG----RWGTVCDDSWDNTDASV------------LLT-------------------------------NCRN--STTRN--
||||.|.|..|||||  |||    .|||||||.|| .||.|              .                               .|..      |  
VRLVGGNNPCEGRVEVYHNGGGQGQWGTVCDDNWDIRDANVVCRQLGCGGAVSASQTLPATWAHFGQGSGPIWMDNVRCTGTETSLWDCPHWGWGQHNNC

CGN------SKDAGVACH
|.       . |||| | 
CSHNHHRNRQEDAGVVCS
SRCR AqueK350.AA SRCR 145-167 33 0.00848 11.21 Pfam 83-112 (112) Show / Hide 
Range on Protein: 145-167
Range on HMM: 83-112/112
Sequence Identity: 33% (10 aa)

LTNC--RNSTT--RN--CGNS-KDAGVACH
|..|  ....   .|  |. |  |||| | 
LWQCPHSPWGWHRHNPMCSHSREDAGVICS
SRCR AqueK350.AA SRCR 177-244 48 4.3e-31 106.26 Pfam 1-78 (112) Show / Hide 
Range on Protein: 177-244
Range on HMM: 1-78/112
Sequence Identity: 48% (38 aa)

VNGSNSTEGRVELCH-NGRWGTVCDD-S-WDNTDASVVCRQLGYGPG---IAFYDPY--FG--QGNRSVVIDDVDCNG
|.||.. |||||... ||.||||||| . ||..||.|||||||.|.|     .  .|  ||  .|.  ...|.|.|.|
VGGSSPCEGRVEVRYHNGQWGTVCDDDGNWDMRDAHVVCRQLGCGGGAVQAWSCCAYAWFGNCPGTGPIWMDNVRCHG
SR AqueK350.AA SR 174-264 36 2.1e-26 94.93 SMART 1-118 (118) Show / Hide 
Range on Protein: 174-264
Range on HMM: 1-118/118
Sequence Identity: 36% (44 aa)

VRLVNGSNSTEGRVELCHNG----RWGTVCDDSWDNTDASVVCRQLGYGPGIAFY------DPYFGQGNRSVVIDDV----------DCNG--IINVSTN
||||.|.|. |||||  |||    .|||||||.|| .||.|||||||.| ... .      . .||||..  . |.|          ||    . . ...
VRLVGGNNPCEGRVEVYHNGGGQGQWGTVCDDNWDIRDANVVCRQLGCGGAVSASQTLPATWAHFGQGSGPIWMDNVRCTGTETSLWDCPHWGWGQHNNC

PASN------QLSSILVPV
  |       |    .|  
-CSHNHHRNRQEDAGVVCS
Pkinase_Tyr AqueK350.AA Pkinase_Tyr 330-533 36 1.6e-77 263.14 Pfam 1-197 (270) Show / Hide 
Range on Protein: 330-533
Range on HMM: 1-197/270
Sequence Identity: 36% (78 aa)

ISMQETAGQGEFGIVYRGVMT-KKNQMSQAVAIKTLKGFYNKSD--IDSLLDECITMMSF-DNLNVLPLIGVCLDLGPA--PCIVMPFMSRGNLLSYLKK
|.. .. |.|.|| ||.|... .. .  . ||.|.||  . ...  ..... |  .|... .. |.. |.|||.| |    ..|||..|  |.||.||.|
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

ERLNLTVADTCEEDVILNVRKQLLSICLQVANGMSYLASQKFVHRDLAARNCMIDDDGIIKVADFGLSEDIYDQNYF-RQRKNSSATIKLPVKWMAIESL
 |         |..  |..   ||..|.|.|.||.||.|....|||||||||........|..||||. |||.  |  |.|...    |||.|||| |..
HR---------EDKQPLTMKD-LLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGG----KLPIKWMAPECI

HDGLYSEKSDV
..| ...||||
NYGKFTTKSDV
Kinase AqueK350.AA Met 331-533 39 4.6e-69 225.5 In-house 1-202 (271) Show / Hide 
Range on Protein: 331-533
Range on HMM: 1-202/271
Sequence Identity: 39% (85 aa)

SMQETAGQGEFGIVYRGVMTKKNQMSQAVAIKTLK--GFYNKSDIDSLLDECITMMSFDNLNVLPLIGVCLDLGP-APCIVMPFMSRGNLLSYLKKERLN
 . .  ||| || ||.| .. . .    .|.|.|.         |   | | |.|  ||  ||| |||.|||     | .| |.|  | |... . .  |
HFDDVIGQGHFGCVYHGMYHDNDGNEHHCACKSLHGERITDIQHISQFLREGIMMKHFDHPNVLSLIGICLDPEGHMPWVVLPYMKHGDLKTFIRNPQNN

LTVADTCEEDVILNVRKQLLSICLQVANGMSYLASQKFVHRDLAARNCMIDDDGIIKVADFGLSEDI-YDQNYFRQRKNSS-ATIKLPVKWMAIESLH--
..|             ..|.. |.||| ||.|.|||||||||||.||||.| . ..|||||||. |. ||  |  |.     |  .||||||| |.|   
PCV-------------RDLIEFCHQVAKGMMYMASQKFVHRDLACRNCMLDEHFTVKVADFGLCRDMDYDKEYYSQMHHTHPA--RLPVKWMAPECLQQG

------DGL-YSEKSDV
      .   .. ||||
VCLGCPTYRQFTTKSDV
Kinase AqueK350.AA TK 330-533 21 9.4e-65 215.72 In-house 1-377 (486) Show / Hide 
Range on Protein: 330-533
Range on HMM: 1-377/486
Sequence Identity: 21% (81 aa)

ISMQETAGQGEFG---IVYRGVMTK----------------------KNQMSQAVAIKTLKGFYNKSDIDSLL---------------DECITMMS---F
| . .. |.|.||    ||.| .                        |..  . ||.|.||   . |. . ..                | . ||.   .
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

DNLNVLPLIGVCLDLG-----------PAPCIVMPFMSRGN----LLSYLKKERLNLTV-----------------------------------------
.  |.. |.|||.. .           . ..||| .|. |.    |..||.| | . .                                          
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

--------ADTCEEDVILN-------------VRKQLLSICLQVANGMSYLASQ------KFVHRDLAARNCMIDDDGI-----------IKVADFG---
         ... .   |.               .||| .|.|.|.||.||.|.      .|||||||||||.......           .|.||||   
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----LSEDIY-DQNYFRQRKNSSA-------------------TIKLPVKWMAIESLHDGL---------YSEKSDV
     |. ||| |..| |..  . .                     |||..||| |.| |.          ...||||
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDV
Kinase AqueK350.AA UTK 330-533 29 1.7e-56 191.78 In-house 1-223 (296) Show / Hide 
Range on Protein: 330-533
Range on HMM: 1-223/296
Sequence Identity: 29% (69 aa)

ISMQETAGQGEFGIVYRGVMTK-KNQMSQ-AVAIKTLKGFYNKSD----ID---SLLDECI---TMMSFD-NLNVLPLIGVCLDLGPAPCIVMPFMSRGN
.   .. |||.||.|...  |. ...| . .||.|...   ...|     .    .. |.     |. |.   ||| |.|||.. .| ..||. .|..|.
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQ---HHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEP-WMIVTEYMENGD

LLSYLKKERLNLTVADTCEEDVILNVRKQLLSICLQVANGMSYLASQKFVHRDLAARNCMIDDDG-------IIKVADFG---LSEDIY---------DQ
|.||| . | ..      .....|. . |.|. ....|.||.||.|..||||||||||| .....       ..|.||||   .| ...         ..
LRSYLRRHRPTPP-----ACPHWLTLH-QRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWES

NYFRQRKNSSATIKLPVKWMAIESLHDG-LYSEKSDV
.|.... .     ..|..||| |.| ..  ...||||
YYYMAQHQD----RWPIRWMAPEALTHHTRFTTKSDV
Kinase AqueK350.AA TK-Unique 330-533 29 3e-54 185.46 In-house 1-222 (294) Show / Hide 
Range on Protein: 330-533
Range on HMM: 1-222/294
Sequence Identity: 29% (67 aa)

ISMQETAGQGEFGIVYRGVMTKKN---QMSQAVAIKTLKGFYNKSDIDSLLDECITMMSFD-NLNVLPLIGVCLDLGPAPCIVMPFMSRGNLLSYLKKER
. .... |.|.|| |.|| .....      . ||.|.||   .. | . .|.|   |.. .   |.. ..|.| . .  ..|.|.....|||..||.. |
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR

-LNLTV---------ADTCEEDVILN-VR-KQLLSICLQVANGMSYLAS--QKFVHRDLAARNCMIDDDGIIKVADFGLSEDIYDQNYFRQRKNSSAT--
    ..         ... .... .. .  |.|.... |.|.||.||||  .|.|||||.|||... .|...|..|||...|.|.      ...|. .  
PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYT-----NGVYSMMCSQ

IKLPVKWMAIESLH--DGLY-SEKSDV
 ..|..||| |||   .| | ..||||
GRIPIRWMAPESLKCYHGMYHTTKSDV
Kinase AqueK350.AA TyrKc 330-556 26 5.9e-53 183.16 SMART 1-280 (280) Show / Hide 
Range on Protein: 330-556
Range on HMM: 1-280/280
Sequence Identity: 26% (81 aa)

ISMQETAGQGEFGIVYRGVMTKKNQMSQAVAIKTLKGFYNKSDIDSLLDECITMMSF--DNLNVLPLIGVCLDLG------PAPCIVMPFMSRGNLLSYL
|.. .. | |.||.||.|...      . ||.|.||       .  ...|   |...  .. |.. |.|||.. |      . ..||| .|. |.|..||
ITLGKKLGEGAFGEVYKGTWK------IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYL

KKERLNLTVADTCEEDVILNVRKQLLSICLQVANGMSYLASQKFVHRDLAARNCMIDDDGIIKVADFGLSEDIYDQ-------NYFRQRKNSSATIKLPV
.| | .            |.. |.|||.|.|.|.||.||.|....|||||||||........|..||||| ||||         | |... ...   ||.
RKHRPK------------LCM-KDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPI

KWMAIESLHDGLYSEKSDV---------------------------------------RLFLYSG---------------LMVSCAGK-------FSVLV
.|||.|.. .| ...||||                                       |.                    .| .|          || ..
RWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIH

GYL
 ..
ECF
Kinase AqueK350.AA Axl 330-536 38 5.9e-51 175.6 In-house 1-201 (267) Show / Hide 
Range on Protein: 330-536
Range on HMM: 1-201/267
Sequence Identity: 38% (83 aa)

ISMQETAGQGEFGIVYRGVMTKKNQMSQAVAIKTLK-GFYNKSDIDSLLDECITMMSFDNLNVLPLIGVCLDLG-----PAPCIVMPFMSRGNLLSYLKK
. .  . |.|||| |  | . .    .. ||.|..|     .|.|.  | | . |  ||  ||. |||||. .      |.| ...|||  | | ..|  
FVLGKMLGEGEFGSVMEGQLKQEDGSFVKVAVKMMKIDICTQSEIEEFLSEAACMKEFDHPNVMRLIGVCIQMSERQRIPKPMVILPFMKHGDLHTFLLY

ERLNLTVADTCEEDVILNVRKQLLSICLQVANGMSYLASQKFVHRDLAARNCMIDDDGIIKVADFGLSEDIYDQNYFRQRKNSSATIKLPVKWMAIESLH
 ||.       .. . | . . |.   . .| || ||....|.||||||||||. .|  . |||||||  ||.  |.|| . .    |.||||.||||| 
SRLG-------DQPFYLPL-QMLVKFMVDIACGMEYLSNRNFIHRDLAARNCMLREDMTVCVADFGLSKKIYSGDYYRQGCIA----KMPVKWIAIESLA

DGLYSEKSDVRLF
| .|  ||||  |
DRVYTSKSDVWAF
Kinase AqueK350.AA InsR 330-533 35 6.7e-50 165.73 In-house 1-204 (278) Show / Hide 
Range on Protein: 330-533
Range on HMM: 1-204/278
Sequence Identity: 35% (75 aa)

ISMQETAGQGEFGIVYRG----VMTKKNQMSQAVAIKTLKGFYNKSDIDSLLDECITMMSFDNLNVLPLIGVCLDLGPAPCIVMPFMSRGNLLSYLKKER
| .    ||| || || |    ..      . ..||||..      .    | |   |  |.  .|  | |||    |.  .|| .| .|.| |||   |
IVLIRECGQGSFGMVYEGIAKGIVPDEEWRFGRCAIKTVNENASMRERIEFLNEASVMKEFNCHHVVRLLGVCSRGQPM-YVVMEMMTYGDLKSYLRSRR

LNLT-VADTCEEDVILNVRKQLLSICLQVANGMSYLASQKFVHRDLAARNCMIDDDGIIKVADFGLSEDIYDQNYFRQRKNSSATIKLPVKWMAIESLHD
         |.. .    . |...   ... ||.|||. ||||||||.||||...|. .|..|||.  |||.  | |  . .    .||| ||| ||| |
PEEEFNNPGCNRNQHVPCLDQMHQMAAEICDGMAYLAAKKFVHRDLACRNCMVNHDFTVKIGDFGMTRDIYEHDYYRKGGKG----MLPVRWMAPESLKD

GLYSEKSDV
| .. .|||
GVFTTHSDV
Kinase AqueK350.AA Abl 330-536 38 2.4e-40 131.99 In-house 1-184 (252) Show / Hide 
Range on Protein: 330-536
Range on HMM: 1-184/252
Sequence Identity: 38% (79 aa)

ISMQETAGQGEFGIVYRGVMTKKNQMSQAVAIKTLKGFYNKSDIDSLLDECITMMSFDNLNVLPLIGVCLDLGPAPCIVMPFMSRGNLLSYLKKERLNLT
|.|..  | | .| || ||  . ...   ||.||||   .  ...  | |   |      |.  |.|||    |   |.  ||. |||| ||..      
IMMKHKLGGGQYGEVYEGVWKRHDCT---VAVKTLK--EDTMEVHEFLKEAAIMKEMKHPNLVQLLGVCTREPPF-YIITEFMCYGNLLDYLRE------

VADTCEEDVILNVRKQLLSICLQVANGMSYLASQKFVHRDLAARNCMIDDDGIIKVADFGLSEDIYDQNYFRQRKNSSATIKLPVKWMAIESLHDGLYSE
    |... .  |   || .  |.| ||||| ...|.|||||||||.. .. |.|||||||.  . |. |  .     |  | |.|| | |||    .| 
----CDREELPAV--VLLYMATQIASGMSYLEKRHFIHRDLAARNCLVGEHHIVKVADFGLARMMKDDTYTAH-----AGAKFPIKWTAPESLAYNKFSS

KSDVRLF
||||  |
KSDVWAF
Kinase AqueK350.AA Fer 330-533 31 3.1e-39 131.32 In-house 1-201 (283) Show / Hide 
Range on Protein: 330-533
Range on HMM: 1-201/283
Sequence Identity: 31% (70 aa)

ISMQETAGQGEFGIVYRG--VMTKKNQMSQAV---AIKTLKG---FYNKSDIDSLLDECITMMS-FDNLNVLPLIGVCLDLGPAPCIVMPFMSRGNLLSY
. ...  | | ||.||.|  ... |....  |   |.|. |    . .|  |  .. |   |.. .|  ||  ..||| |  |   ||| |.. |.|.||
VTLGKKLGEGAFGEVYKGRRTLKCKKGKWHVVNKVAVKVKKCKCEDATKEQIKEFMHEARIMRNNYDHPNVVKFYGVCVDEQPI-MIVMEFCNGGSLDSY

LKKERL-NLTVADTCEEDVILNVRKQLLSICLQVANGMSYLASQKFVHRDLAARNCMIDDDGIIK---VADFGLSED----IYDQN--YFRQRKNSSATI
|||.   ....             .... .|.|.|.|| || |.. .|||.||||| ...|.. |   ..|||.| .    .||             .  
LKKNKNKTVSD-------------NEKIRMCYQAACGMEYLHSKNCIHRDIAARNCLYHKDKVKKKCKISDFGMSRQCSDYGYDYKMKE--------KAC

KLPVKWMAIESLHDGLYSEKSDV
|.|..|.| |.. .|.||.|.||
KVPIRWLAPETWQTGIYSPKTDV
Kinase AqueK350.AA FGFR 330-533 33 6.8e-39 130.16 In-house 1-221 (293) Show / Hide 
Range on Protein: 330-533
Range on HMM: 1-221/293
Sequence Identity: 33% (76 aa)

ISMQETAGQGEFGIVYRGVMT--KKN--QMSQAVAIKTLKGFYNKSDIDSLLDECITM-MSFDNLNVLPLIGVCLDLGPAPCIVMPFMSRGNLLSYLKKE
 .. .. | | || | ..     ...  .   .||.| ||      |. .|  |  .| |   . |.. |.|.|   || . ..  . ..|||  .|.. 
LTLGKMLGEGCFGQVWMAEAKGIDCDRPEKEITVAVKMLKMNHTDKDLSDLVSEMEMMKMIGKHKNIINLLGCCTQEGP-LYVIVEYCHHGNLRDFLRAR

RLNL--TVADTC----------EED----VILN-VRKQLLSICLQVANGMSYLASQKFVHRDLAARNCMIDDDGIIKVADFGLSEDIYDQNYFRQRKNSS
|        |..          |.     .| |   |.| |.  ||| || ||||.| .||||||||  . || ..|..||||. || .  |.| . |  
RPPGMDYKKDSQEYTDYKPRKPEQQDDIELIPNLTQKDLVSCAYQVARGMEYLASRKCIHRDLAARNVLVTDDYVMKICDFGLARDIHCIDYYRKTTNG-

ATIKLPVKWMAIESLHDGLYSEKSDV
    ||.|||| |.| |  |  .|||
---RLPIKWMAPEALFDRVYTHQSDV
Kinase AqueK350.AA Csk 330-533 35 1.2e-37 126.04 In-house 1-180 (251) Show / Hide 
Range on Protein: 330-533
Range on HMM: 1-180/251
Sequence Identity: 35% (73 aa)

ISMQETAGQGEFGIVYRGVMTKKNQMSQAVAIKTLKGFYNKSDIDSLLDECITMMSFDNLNVLPLIGVCLDLGPAPCIVMPFMSRGNLLSYLKKERLNLT
. . |. |.|||| |  |         . ||.| .|.  |   ....|.|   |      |   |||| |. .    ||| .||.|||. ||        
LHLGECIGHGEFGDVMQGEY-----QNRKVAVKCIKCDGNGM-AQAFLAEASVMTQLRHPNLVQLIGVILHQKNHLYIVMEYMSKGNLVDYLR-------

VADTCEEDVILNVRKQLLSICLQVANGMSYLASQKFVHRDLAARNCMIDDDGIIKVADFGLSEDIYDQNYFRQRKNSS--ATIKLPVKWMAIESLHDGLY
   . .. ||   |.|||   . |..|| || . |||||||||||  ...| . || ||||. .         ....   .. |.|.|| | | |  . .
---SRGRHVI--TRRQLLKFAMDVCEGMCYLEQKKFVHRDLAARNILVSEDCVAKVSDFGLAKE--------ECSQQDDSTSGKFPIKWTAPEALRHKKF

SEKSDV
| ||||
STKSDV
Kinase AqueK350.AA Pkinase 330-507 21 9e-16 56.85 Pfam 1-170 (293) Show / Hide 
Range on Protein: 330-507
Range on HMM: 1-170/293
Sequence Identity: 21% (42 aa)

ISMQETAGQGEFGIVYRGVMTKKNQMSQAVAIKTLKGFYNKSDID--SLL-DECITMMSFDNLNVLPLIGVCLDLGPAPCIVMPFMSRG----NLLSYLK
.   .. |.| || ||...  . ..    ||.|..|   .||. |   ..  |.  | ...  |.. |.... | .. ...||...  |     | .|..
YHIGRKIGSGSFGCVYKCHHKGTGK---IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED-KDHIYMVMEYCEGGLYVMDLFDYIS

KERLNLTVADTCEEDVIL--NVRKQLLSICLQVANGMSYLASQKFVHRDLAARNCMIDDDGII----KVADFGLSEDIYDQNYFRQRKNSS
            ...  .     ... ....|.. |. |. |....||||   |..||..| |    |..||||.. ..   | ... ...
T-----------WRHGCFYFS-EWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD---Y-NNS-MTT
Kinase AqueK350.AA S_TKc 330-556 18 1.1e-12 8.9 SMART 1-231 (231) Show / Hide 
Range on Protein: 330-556
Range on HMM: 1-231/231
Sequence Identity: 18% (51 aa)

ISMQETAGQGEFGIVYRGVMTKKNQMSQAVAIKTLKGFYNKSDIDSLLDECITMMSFDNLNVLPLIGVCLDLGPAPCIVMPFMSR--GNLLSYLKKER--
  . .. |.| || ||... .|     . |||| .|        .... |   ... .  |.  |..|. |     ..|| ...   |.|..|.|| .  
YEILRKIGKGAFGKVYKCRHKK---TGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIKKRGRH

-----LNLTVADTCEEDVILNVRKQLLSICLQVANGMSYLASQKFVHRDLAARNCMIDDDGIIKVADFGLSEDIYDQNYFRQRKNSSATIKLPVKWMAIE
     ..  .|                ... |..... |. |....||||   | ..|.   ||..||||.  .              |.     .|| |
GLRFPFPE-HA---------------RFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------------TTFCGTPWYMAPE

SLHDGLYSE-KSDV--------------------------------RLFLYSGLMVSCA---GKFSVLV--------GYL
 |    |.  |.|.                                . |.   | .  .   .   .|          ..
VL---GYGKCKCDWWSCGCILYEMLCGYPPFPQMQMMFKKIGSPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF