Gene AqueK355 (A.queenslandica)

AqueK355

Species: A.queenslandica
Alias: AqueK355
External Links:
Annotation:

Classification

Group: TK
Family: Met

Sequence

Name Sequence Type Origin Length Description Download
AqueK355.AA Protein None 197 None Fasta, JSON
AqueK355.kin_dom Protein Kinase Domain None 163 None Fasta, JSON

Protein domain

Protein domains of AqueK355.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Pkinase_Tyr AqueK355.AA Pkinase_Tyr 20-188 34 8.4e-62 209.93 Pfam 1-171 (270) Show / Hide 
Range on Protein: 20-188
Range on HMM: 1-171/270
Sequence Identity: 34% (62 aa)

INLQEAVGQGEFGIVYRALLA-TGKDVPQVVAVKTLKGLFSKSN--VASIVEESLIMSNF-DNPNVLSLIGVSLDLGPA--PCIIMPFMSRGSLLSYLKK
| . .  |.|.|| ||.. .   ...  . ||||.||   ....   ..  .|  ||... ..||...|.|| .| |    ..|.|..|  |.||.||.|
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

ERPNITITDGEDEEIILNVRKHLLSICLQVANGMCYLASQYFVHRDLAARNCMIDNNGVIKVADFGLSEEV-----Y-TKT
 |         ...  |..   ||..|.|.|.|| ||.|. ..|||||||||....|.|.|..||||.  .     | .|.
HR---------EDKQPLTMKD-LLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKR
Kinase AqueK355.AA Met 21-189 36 3e-53 172.77 In-house 1-160 (271) Show / Hide 
Range on Protein: 21-189
Range on HMM: 1-160/271
Sequence Identity: 36% (63 aa)

NLQEAVGQGEFGIVYRALLATGKDVPQVVAVKTLK--GLFSKSNVASIVEESLIMSNFDNPNVLSLIGVSLDLGP-APCIIMPFMSRGSLLSYLKKERPN
 . . .||| || ||.. .  ..     .|.|.|.         .    .| ..|. || ||||||||..||     | .. |.|  | |... . .  |
HFDDVIGQGHFGCVYHGMYHDNDGNEHHCACKSLHGERITDIQHISQFLREGIMMKHFDHPNVLSLIGICLDPEGHMPWVVLPYMKHGDLKTFIRNPQNN

ITITDGEDEEIILNVRKHLLSICLQVANGMCYLASQYFVHRDLAARNCMIDNNGVIKVADFGLSEEV-YTKTY
...             . |.. |.||| || |.||| |||||||.||||.|   ..|||||||.  . | | |
PCV-------------RDLIEFCHQVAKGMMYMASQKFVHRDLACRNCMLDEHFTVKVADFGLCRDMDYDKEY
Kinase AqueK355.AA TK 20-189 20 6.5e-49 161.67 In-house 1-314 (486) Show / Hide 
Range on Protein: 20-189
Range on HMM: 1-314/486
Sequence Identity: 20% (64 aa)

INLQEAVGQGEFG---IVYRALLAT----------------------GKDVPQVVAVKTLKGLFSKSNVA----------------SIVEESLIMSN--F
| | .  |.|.||    ||.... .                      ...... ||||.||   . |  .                . .||  .|..  .
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

DNPNVLSLIGVSLDLG-----------PAPCIIMPFMSRGS----LLSYLKKERPNITI----------------------------TDGEDEEIILNV-
. ||...|.||... .           . ..|.| .|. |.    |..||.| ||. .                             .. .... . .  
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPC-PEEQD

--------------RKHLLS-------------------ICLQVANGMCYLASQ------YFVHRDLAARNCMIDNNGV-----------IKVADFG---
               |.||.                   .|.|.|.|| ||.|.       |||||||||||....|.|           .|.||||   
YDDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----LSEEVYTKTY
     |. ..| ...
QGSGVLARDIYSDDD
Kinase AqueK355.AA UTK 20-181 32 6.5e-46 155.06 In-house 1-175 (296) Show / Hide 
Range on Protein: 20-181
Range on HMM: 1-175/296
Sequence Identity: 32% (59 aa)

INLQEAVGQGEFGIVYRALLATGK--DVPQVVAVKTLK-GLFSKSNVA---SIVEESL---IMSNFD-NPNVLSLIGVSLDLGPAPCIIMPFMSRGSLLS
. | .  |||.||.|..| . . .     ..||||... . ..  . .    . ||.    .|..|.  |||| |.|| .. .| ..|.. .|..|.|.|
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEP-WMIVTEYMENGDLRS

YLKKERPNITITDGEDEEIILNVRKHLLSICLQVANGMCYLASQYFVHRDLAARNCMIDNNG-------VIKVADFG---LS
|| . ||.       ... .|. . ..|. ....|.|| ||.|. ||||||||||| .. ..       |.|.||||   .|
YLRRHRPTPP-----ACPHWLTLH-QRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMS
Kinase AqueK355.AA TK-Unique 20-186 29 6.8e-44 149.26 In-house 1-185 (294) Show / Hide 
Range on Protein: 20-186
Range on HMM: 1-185/294
Sequence Identity: 29% (54 aa)

INLQEAVGQGEFGIVYRALLATGK---DVPQVVAVKTLKGLFSKSNVASIVEESLIMSNFD-NPNVLSLIGVSLDLGPAPCIIMPFMSRGSLLSYLKKER
..... .|.|.|| |.|. . ...   | ...||||.||  ...  ..    |  .|.. .  ||.....|.. . .  ..|||.....|.|..||.. |
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR

P---------NITITDGEDEEIILN--VR-KHLLSICLQVANGMCYLAS--QYFVHRDLAARNCMIDNNGVIKVADFGLSEEVYT
|         |. .. . .... ..  .  | |.... |.|.|| ||||  . .|||||.|||... ...|.|..|||....|||
PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYT
Kinase AqueK355.AA TKL 26-181 21 2.5e-35 123.68 In-house 1-201 (364) Show / Hide 
Range on Protein: 26-181
Range on HMM: 1-201/364
Sequence Identity: 21% (48 aa)

VGQGEFGIVYRALLAT------GKDVPQVVAVKTLKGL--------------------------FSKSNVASIVEESLIMSNFDNPNVLSLIGVSLDLGP
.|.| ||.||.. .        . |  ..||||..|                            ... .   ..|| ..||... ||.....|.... ..
IGSGGFGEVYKGKWRGWGGKCPS-DTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPC

A------------PCIIMPFMSRGSLLSYLKKERPNITITDGEDEEIILNVRKHLLSICLQVANGMCYLASQY--------FVHRDLAARNCMIDNNGV-
             .||.| ....||||.||                       ......|..| ||.|| |.          .||||  .|...|.|.  
GCVCMHPVGPWGQLCIVMEYCPGGSLLHYLH--------------------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTN

-------------IKVADFGLS
             .|..|||||
VSNYMYNPNADWCCKICDFGLS
Kinase AqueK355.AA Axl 20-192 35 5.9e-35 121.15 In-house 1-171 (267) Show / Hide 
Range on Protein: 20-192
Range on HMM: 1-171/267
Sequence Identity: 35% (64 aa)

INLQEAVGQGEFGIVYRALLATGKDVPQVVAVKTLK-GLFSKSNVASIVEESLIMSNFDNPNVLSLIGVSLDLG-----PAPCIIMPFMSRGSLLSYLKK
. |   .|.|||| |  . |       . ||||..|   ...|..   . |   | .|| |||. ||||.. .      |.| .|.|||  | | ..|  
FVLGKMLGEGEFGSVMEGQLKQEDGSFVKVAVKMMKIDICTQSEIEEFLSEAACMKEFDHPNVMRLIGVCIQMSERQRIPKPMVILPFMKHGDLHTFLLY

ERPNITITDGEDEEIILNVRKHLLSICLQVANGMCYLASQYFVHRDLAARNCMIDNNGVIKVADFGLSEEVYTKTYFNQ
 |        .|. . | . . |.   . .| || ||... |.||||||||||. ..  . |||||||  .|   |. |
SRL-------GDQPFYLPL-QMLVKFMVDIACGMEYLSNRNFIHRDLAARNCMLREDMTVCVADFGLSKKIYSGDYYRQ
Kinase AqueK355.AA ALK 20-190 35 1.7e-32 109.48 In-house 1-171 (273) Show / Hide 
Range on Protein: 20-190
Range on HMM: 1-171/273
Sequence Identity: 35% (63 aa)

INLQEAVGQGEFGIVYRALLAT--GKDVPQVVAVKTLKGLFSKSNVASIVEESLIMSNFDNPNVLSLIGVSLDLGPAPCIIMPFMSRGSLLSYLKKERPN
| |  | |.| || || ..     |  ||  ||.|||. . |.        | |||..|. .|| ..||....  |   |.  .|. | ..|.|.  ||.
ITLVRALGHGAFGEVYMGQYSHMPGDSVPMQVAMKTLPEDCSQQDEEDFCMEALIMGKFNHQNVVRCIGICFQKQPY-MIVLEYMEGGDMKSFLRECRPH

ITITDGEDE--EIILNVRKHLLSICLQVANGMCYLASQYFVHRDLAARNCMIDNNG---VIKVADFGLSEEV-YTKTYF
        |     . . | || .|. || |  || .. |.||| |||||     |   | |.|||| . .. |   |.
-------PESLQPSQLTMKDLLQCCCDVAQGCHYLEENHFIHRDIAARNCLLTCKGPGRVAKIADFGMARDITYRADYY
Kinase AqueK355.AA Musk 20-190 33 1.9e-32 104.4 In-house 1-182 (282) Show / Hide 
Range on Protein: 20-190
Range on HMM: 1-182/282
Sequence Identity: 33% (62 aa)

INLQEAVGQGEFGIVYRA----LLATGKDVPQVVAVKTLKGLFSKSNVASIVEESLIMSNFDNPNVLSLIGVSLDLGPAPCIIMPFMSRGSLLSYLKKER
|     .|.| || |. |    |..  ...  .|||| ||   ||   .    |  .|  ||.||.  | ||   .|   |  . .|. | |  .|.   
IIYVRDIGEGAFGRVFQARAPGLVPYEEET--MVAVKMLKDDASKQMQMDFQREACMMAEFDHPNIVKLLGVCF-VGRPMCLLFEYMAYGDLNEFLHSCS

PNITITDGEDEE-----------IILNVRKHLLSICLQVANGMCYLASQYFVHRDLAARNCMIDNNGVIKVADFGLSEEVYTKTYF
|  |     ..              |.   |.| .  |.| || ||    ||||||| |||.|  . ..|.|||||| ..| . |.
PHRTCSRTHQDRGMRAQVSSPGPPQLKCY-HQLCMAKQIACGMAYLSEMMFVHRDLATRNCLINEHMDVKIADFGLSRYIYHQDYY
Kinase AqueK355.AA Fer 20-188 30 1.5e-31 104.8 In-house 1-172 (283) Show / Hide 
Range on Protein: 20-188
Range on HMM: 1-172/283
Sequence Identity: 30% (57 aa)

INLQEAVGQGEFGIVYRA------LLATGKD-VPQVVAVKTLKGLFSKSN-VASIVEESLIMSN-FDNPNVLSLIGVSLDLGPAPCIIMPFMSRGSLLSY
..|..  | | ||.||..      ..... . ..  |.||..|. ...    . .  |  || | .| |||  ..||. |  |   |.| |.. |||.||
VTLGKKLGEGAFGEVYKGRRTLKCKKGKWHVVNKVAVKVKKCKCEDATKEQIKEFMHEARIMRNNYDHPNVVKFYGVCVDEQPI-MIVMEFCNGGSLDSY

LKKERP-NITITDGEDEEIILNVRKHLLSICLQVANGMCYLASQYFVHRDLAARNCMIDNNGVIK---VADFGLSEE----VYTKT
|||.   ....             . .. .|.|.|.|| || |.  .|||.||||| .....| |   ..|||.| .    .|...
LKKNKNKTVSD-------------NEKIRMCYQAACGMEYLHSKNCIHRDIAARNCLYHKDKVKKKCKISDFGMSRQCSDYGYDYK
Kinase AqueK355.AA Ror 20-185 31 2.9e-31 110.2 In-house 1-170 (308) Show / Hide 
Range on Protein: 20-185
Range on HMM: 1-170/308
Sequence Identity: 31% (54 aa)

INLQEAVGQGEFGIVYRALLATGK--DVPQVVAVKTLKGLFSKSNVASIVEESLIMSNFDNPNVLSLIGVSLDLGPAPCIIMPFMSRGSLLSYLKKERP-
.   |. | . || ||.  |  .   . .. ||.||.|   |    .    |  .|. .. ||.  |.|| .   |  | .  .|. | |   |.   | 
VRFMEELGECQFGKVYKGHLMGPNFMYHCMAVAIKTCKHDASPAQWQDFRQEIMLMATLHHPNIVCLLGVCTMDQPY-CMLFEYMNHGDLHEFLIMRSPH

-NITITDGED-EEIILNVRKHLLSICLQVANGMCYLASQYFVHRDLAARNCMIDNNGVIKVADFGLSEEVY
       ..|  . .       | | .|.| || ||.| .|||||||||||..    ..|..||||. ..|
SDHGCSSDDDRMVKSSLDHPDFLHIAIQIAAGMEYLSSHHFVHRDLAARNCLVGEHHHVKISDFGLMRDIY
Kinase AqueK355.AA Pkinase 20-192 24 3.3e-22 79.6 Pfam 1-166 (293) Show / Hide 
Range on Protein: 20-192
Range on HMM: 1-166/293
Sequence Identity: 24% (46 aa)

INLQEAVGQGEFGIVYRALLATGKDVPQVVAVKTLKGLFSKSNVASIVE---ESLIMSNFDNPNVLSLIGVSLDLGPAPCIIMPFMSRG----SLLSYLK
. . . .|.| || ||..      .   .||||..|    ||..  .     |  || ... ||.. |...  | .. ....|...  |    .| .|..
YHIGRKIGSGSFGCVYKCHHKGTGK---IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED-KDHIYMVMEYCEGGLYVMDLFDYIS

KERPNITITDGEDEEIIL--NVRKHLLSICLQVANGMCYLASQYFVHRDLAARNCMIDNNGVI----KVADFGLSEEVYTKTYFNQ
            ...  .     ... ....|.. |. |. |. ..||||   |..|||||.|    |..||||.. ..   | |.
T-----------WRHGCFYFS-EWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD---Y-NN
Kinase AqueK355.AA TyrKc 20-193 21 7.5e-17 49.79 SMART 1-280 (280) Show / Hide 
Range on Protein: 20-193
Range on HMM: 1-280/280
Sequence Identity: 21% (66 aa)

INLQEAVGQGEFGIVYRALLATGKDVPQVVAVKTLK-GLFSKSNVASIVEESLIMSNF--DNPNVLSLIGVSLDLG------PAPCIIMPFMSRGSLLSY
| | .  | |.||.||.. .       . ||||.|| .      .. . .|  ||...  ..||.. |.|| .. |      . ..|.| .|. |.|..|
ITLGKKLGEGAFGEVYKGTWK------IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDY

LKKERPNITITDGEDEEIILNVRKHLLSICLQVANGMCYLASQYFVHRDLAARNCMIDNNGVIKVADFGLSEEVYTK--------TYF------------
|.| ||.            |.. |.|||.|.|.|.|| ||.|. ..|||||||||....|...|..||||| ..| .        .|             
LRKHRPK------------LCM-KDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLP

-----------------------------------------------------------------N----------------------------------
                                                                 |                                  
IRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI

--QF
  .|
HECF
Kinase AqueK355.AA S_TKc 20-194 15 8.3e-10 -33.06 SMART 1-231 (231) Show / Hide 
Range on Protein: 20-194
Range on HMM: 1-231/231
Sequence Identity: 15% (41 aa)

INLQEAVGQGEFGIVYRALLATGKDVPQVVAVKTLKGLFSKSNVASIVEESLIMSNFDNPNVLSLIGVSLDLGPAPCIIMPFMSR--GSLLSYLKKERPN
  . . .|.| || ||..         ..||.| .|         .|  |  |... . ||.  |..|  |     ...| ...   |.|..|.|| ...
YEILRKIGKGAFGKVYKCRHKK---TGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIKKRGRH

-----ITITDGEDEEIILNVRKHLLSICLQVANGMCYLASQYFVHRDLAARNCMIDNNGVIKVADFGLSEEV----------------YTK---------
     ..  .               ... |..... |. |. ..||||   | ..|.  .||..||||. ..                |.|         
GLRFPFPE-H-------------ARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQLTTFCGTPWYMAPEVLGYGKCKCDWWSCG

------------------------------------TY----------FN--------QFK
                                    ..          ..        .. 
CILYEMLCGYPPFPQMQMMFKKIGSPEAKDFIRKCLQKDPEKRPTAEALQDEWDIKCHPWF