Gene AqueK360 (A.queenslandica)

AqueK360

Species: A.queenslandica
Alias: AqueK360
External Links:
Annotation:

Classification

Group: TK
Family: Met

Sequence

Name Sequence Type Origin Length Description Download
AqueK360.AA Protein None 350 None Fasta, JSON
AqueK360.kin_dom Protein Kinase Domain None 203 None Fasta, JSON

Protein domain

Protein domains of AqueK360.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Pkinase_Tyr AqueK360.AA Pkinase_Tyr 1-203 40 2.9e-79 269.09 Pfam 86-270 (270) Show / Hide 
Range on Protein: 1-203
Range on HMM: 86-270/270
Sequence Identity: 40% (83 aa)

MPFMSRGSLLSYLKKERPNLTVADTSEGDIILNVRKQLLSICLQVANGMSYLASERFIHRDLAARNCMIDDNGIIKVADFGQSEDIYACNYFRQLKGSDN
|..|  |.||.||.| |         |..  |..   ||..|.|.|.||.||.| ..||||||||||....|...|..||| . ||         . .  
MEYMPHGDLLDYLRKHR---------EDKQPLTMKD-LLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDI--------YNDDYY

-NSGSSTVKLPVKWMALESLHDGLFSEKSNVWSYGVLCWEVFSLGKVP-YPGLDPIGVVELL-DTGGRLQCPHNGACSQEIYLVMLSCWSESPNDRPVFS
  .....  ||.||||.|....| |..|| |||.|||.||.|..|. | |||...  |.|.. . |.|. ||.|  |..||| .|..|| . |.||| ||
YRKRGGGK-LPIKWMAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPEN--CPDEIYDLMKQCWHYDPEDRPTFS

DLVSSI
.... .
EIHEQL
Kinase AqueK360.AA TK 1-203 22 4.3e-74 247.58 In-house 134-486 (486) Show / Hide 
Range on Protein: 1-203
Range on HMM: 134-486/486
Sequence Identity: 22% (84 aa)

MPFMSRGS----LLSYLKKERP-----------------------------NLTVADTSEGDIILNV---------------RKQLLS------------
| .|. |.    |..||.| ||                             ..  .. .... . .                 |.||.            
MEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITY-SHESNSPC-PEEQDYDDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQ

-------ICLQVANGMSYLASE------RFIHRDLAARNCMIDDNGI-----------IKVADFG--------QSEDIY-------------ACNYFRQL
       .|.|.|.||.||.|       .|.|||||||||....|..           .|.||||         . |||             .... .  
LTMHQLLMCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQGSGVLARDIYSDDDYYRKSSYGTGRPM-W--

KGSDNNSGSS--------------TVKLPVKWMALESLHDGL---------FSEKSNVWSYGVLCWEVFSLGKVPYPGLDPI----------GVVELLDT
         .                |||..||| |.| |.          |..|| |||.|||.||.|..|..||.|  .            |.|.| .
---------PFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMSNQDVWKDGDNQEVMEYLRR

GGR------------LQCPHNGACS--------------QEIYLVMLSCWSESPNDRPVFSDLVSSI
|||            ...|    |.              .|.|..|..||.. |.||| ||.|.. .
GGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase AqueK360.AA TK-Unique 1-203 33 1.3e-67 230.9 In-house 84-294 (294) Show / Hide 
Range on Protein: 1-203
Range on HMM: 84-294/294
Sequence Identity: 33% (74 aa)

MPFMSRGSLLSYLKKERP---------NLT-VADTSEGDIILN-VR-KQLLSICLQVANGMSYLAS--ERFIHRDLAARNCMIDDNGIIKVADFGQSEDI
|.....|.|..||.. ||         ||   ... . .  .. .  |.|.... |.|.||.||||  ....||||.|||... .....|..||| ..|.
MEYCPCGNLQHYLRTCRPAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDV

YACNYFRQLKGSDNNSGSSTVKLPVKWMALESLH--DGLF-SEKSNVWSYGVLCWEVFSLGKVPYPGLDPIGVVELLDTGGRLQCPHNGAC-SQEIYLVM
|.        . ....  |  ..|..|||.|||   .| . ..||.|||.||| ||.|.||. ||||...  ..|..  | |.. | .  | |.|.| .|
YT--------NGVYSMMCSQGRIPIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYRMPQPEH--CCSHEMYNLM

LSCWSESPNDRPVFSDLVSSI
 |||...| .|| |..... .
KSCWQWEPEERPSFRQIKHRL
Kinase AqueK360.AA Met 2-197 37 7.9e-63 204.71 In-house 83-271 (271) Show / Hide 
Range on Protein: 2-197
Range on HMM: 83-271/271
Sequence Identity: 37% (80 aa)

PFMSRGSLLSYLKKERPNLTVADTSEGDIILNVRKQLLSICLQVANGMSYLASERFIHRDLAARNCMIDDNGIIKVADFGQSEDI-YACNYFRQLKGSDN
|.|  | |... . .  |..|             ..|.. |.||| ||.|.|| .|.|||||.||||.|   ..|||||| . |. |   |  |      
PYMKHGDLKTFIRNPQNNPCV-------------RDLIEFCHQVAKGMMYMASQKFVHRDLACRNCMLDEHFTVKVADFGLCRDMDYDKEYYSQM-----

NSGSSTV--KLPVKWMALESLH--------DGL-FSEKSNVWSYGVLCWEVFSLGKVPYPGLDP-IGVVELLDTG--GRLQCPHNGACSQEIY-LVMLSC
   . |   .|||||||.|.|         .   |. || ||| ||. || .  | .|||  |. . .   | .|   ||  |    |   .|  |||.|
---HHTHPARLPVKWMAPECLQQGVCLGCPTYRQFTTKSDVWSFGVVMWELMTRGAPPYPHVDNWFDITHWLHQGETRRLPQPEY--CPDHLYTDVMLCC

WSESPNDRPVFS
|. .| ||| ||
WHANPEDRPQFS
Kinase AqueK360.AA UTK 1-203 33 2.2e-60 205.28 In-house 89-296 (296) Show / Hide 
Range on Protein: 1-203
Range on HMM: 89-296/296
Sequence Identity: 33% (73 aa)

MPFMSRGSLLSYLKKERPNLTVADTSEGDIILNVRKQLLSICLQVANGMSYLASERFIHRDLAARNCMIDDNG-------IIKVADFG---QSEDIY---
. .|..|.|.||| . ||..      . . .|. . |.|. ....|.||.||.| .|.||||||||| .....       ..|.||||    | ...   
TEYMENGDLRSYLRRHRPTPP-----ACPHWLTLH-QRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFH

-ACNYFRQLKGSDNNSGSSTVKLPVKWMALESLHDG-LFSEKSNVWSYGVLCWEVFSLGKVPYPGLDPIGVVELLDTGGRLQCPHNGACSQEIYLVMLSC
 .     . ..|.    ..  ..|..||| |.| ..  |..|| |||.||.|||... |..||||.    |.. .  |||.. | . .|. ..| .|..|
FSN----RYWESYYYMAQHQDRWPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRC

WSESPNDRPVFSDLVSSI
|  .| .|| | |||. .
WHYDPQERPDFEDLVQQM
Kinase AqueK360.AA Src 3-203 39 2.5e-59 200.18 In-house 75-255 (255) Show / Hide 
Range on Protein: 3-203
Range on HMM: 75-255/255
Sequence Identity: 39% (81 aa)

FMSRGSLLSYLKKERPNLTVADTSEGDIILNVRKQLLSICLQVANGMSYLASERFIHRDLAARNCMIDDNGIIKVADFGQSEDIYACNYFRQLK-GSDNN
.||.|||| ||||          ..    |... ||...  |||.||.|| | ..|||||||||  ...| . ||||||           | .| . |. 
YMSHGSLLDYLKK----------DGEGRHLHLP-QLIDMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLA---------RLIKEDDDEY

SGSSTVKLPVKWMALESLHDGLFSEKSNVWSYGVLCWEVFSLGKVPYPGLDPIGVVELLDTGGRLQCPHNGACSQEIYL-VMLSCWSESPNDRPVFSDLV
. ..  |.|.||.| | .. | |. || |||.|.| .|... |.||||| .   |.. .. | |. ||||  | .|.|  .|| || ..| .|| |  | 
CARHGAKFPIKWTAPEAINYGRFTIKSDVWSFGILLTEIVTYGRVPYPGMTNHEVLQQVERGYRMPCPHN--CPDELYEQIMLQCWHKDPEQRPTFEYLQ

SSI
.  
WFL
Kinase AqueK360.AA FGFR 36-203 44 5.1e-58 196.33 In-house 136-293 (293) Show / Hide 
Range on Protein: 36-203
Range on HMM: 136-293/293
Sequence Identity: 44% (75 aa)

KQLLSICLQVANGMSYLASERFIHRDLAARNCMIDDNGIIKVADFGQSEDIYACNYFRQLKGSDNNSGSSTVKLPVKWMALESLHDGLFSEKSNVWSYGV
|.| |.  ||| || |||| . |||||||||  . |. ..|..||| . ||    |.|      .  |     ||.||||.|.| |  .  .| ||||||
KDLVSCAYQVARGMEYLASRKCIHRDLAARNVLVTDDYVMKICDFGLARDIHCIDYYRK-----TTNG----RLPIKWMAPEALFDRVYTHQSDVWSYGV

LCWEVFSLGKVPYPGLD-PIGVVELLDTGGRLQCPHNGACSQEIYLVMLSCWSESPNDRPVFSDLVSSI
| ||.. .|  |||.        ..| .| |.  |||  |||||| .| .|| ..| .|| |  || ..
LLWEIMTYGGQPYPHIPSVEELYKYLKEGHRMEKPHN--CSQEIYHMMCQCWHFKPCQRPTFKQLVEYL
Kinase AqueK360.AA KIN6 36-203 39 7.5e-58 189.69 In-house 144-305 (305) Show / Hide 
Range on Protein: 36-203
Range on HMM: 144-305/305
Sequence Identity: 39% (69 aa)

KQLLSICLQVANGMSYLASERFIHRDLAARNCMIDDNG---IIKVADFGQSEDIYACNYFRQLKGSDNNSGSSTVK-LPVKWMALESLHDGLFSEKSNVW
|.|...  |...||.||.| ..|||||||||  ..        |. |||    .|.         . .   |   . ||.||||.|.|    || || ||
KDLYMFAWQICDGMEYLHSKNCIHRDLAARNVLVTEGCRMKTCKISDFGLCRYPYM---------DQFQYTSKGGRYLPIKWMAPECLKHYEFSYKSDVW

SYGVLCWEVFSLGKVPYPGLD-PIGVVELLDTGGRLQCPHNGACSQEIYLVMLSCWSESPNDRPVFSDLVSSI
|.||| .|.|||| ||||..  |  . | .  |.|.. | .  |. ||| .| |||.| | ||| |...   .
SFGVLMFEMFSLGDVPYPEMQRPTEMIEHHRSGRRPKHPKW--CPEEIYDIMQSCWQEKPDDRPEFNEMRMQF
Kinase AqueK360.AA VEGFR 36-203 42 9.7e-57 194.81 In-house 173-332 (332) Show / Hide 
Range on Protein: 36-203
Range on HMM: 173-332/332
Sequence Identity: 42% (73 aa)

KQLLSICLQVANGMSYLASERFIHRDLAARNCMIDDNGIIKVADFGQSED-IYAC-NYFRQLK-GSDNNSGSSTVKLPVKWMALESLHDGLFSEKSNVWS
. |..  .|||.|| .|||   |||||||||  .. | ..|  ||| . . ||   .| |. . |          .|| ||||.||. |  .. .| |||
EDLICYSFQVARGMEFLASRKCIHRDLAARNILLCENNVVKICDFGLARHGIYKDPDYVRKGDQG----------RLPIKWMAPESIFDKVYTTYSDVWS

YGVLCWEVFSLGKVPYPGLD-PIGVVELLDTGGRLQCPHNGACSQEIYLVMLSCWSESPNDRPVFSDLVSSI
|||. ||.||||..|||| .        |  | |.  |    | .||| .||.||.. |. || ||.||   
YGVFLWEIFSLGGSPYPGVQIDEEFCNRLKDGYRMRAPD--YCTPEIYHIMLDCWHKEPEERPHFSELVEHL
Kinase AqueK360.AA ALK 38-205 44 1.6e-54 186.62 In-house 113-273 (273) Show / Hide 
Range on Protein: 38-205
Range on HMM: 113-273/273
Sequence Identity: 44% (76 aa)

LLSICLQVANGMSYLASERFIHRDLAARNCMIDDNG---IIKVADFGQSEDI-YACNYFRQLKGSDNNSGSSTVKLPVKWMALESLHDGLFSEKSNVWSY
|| .|. || |  || . .||||| |||||     |   . |.|||| . || |   |.|         |  .  .|||||  | . ||.|  |. |||.
LLQCCCDVAQGCHYLEENHFIHRDIAARNCLLTCKGPGRVAKIADFGMARDITYRADYYRK--------GGRAM-MPVKWMPPEAFMDGIFTSKTDVWSF

GVLCWEVFSLGKVPYPGLDPIGVVELLDTGGRLQCPHNGACSQEIYLVMLSCWSESPNDRPVFSDLVSSINA
||||||.|||| .||||     | |.. .|||.  | |  | | .| .|  ||   | ||| | ... .| .
GVLCWEIFSLGYMPYPGRHNQEVMEFVTEGGRMDPPRN--CPQPVYRIMTQCWQHQPEDRPKFVTILEHIQY
Kinase AqueK360.AA TyrKc 1-203 28 4.2e-49 170.35 SMART 1-280 (280) Show / Hide 
Range on Protein: 1-203
Range on HMM: 1-280/280
Sequence Identity: 28% (85 aa)

M-----------------------------------------------------------------------------PFMSRGSLLSYLKKERPNLTVA
                                                                               .|. |.|..||.| ||.    
ITLGKKLGEGAFGEVYKGTWKIQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK----

DTSEGDIILNVRKQLLSICLQVANGMSYLASERFIHRDLAARNCMIDDNGIIKVADFGQSEDIYAC-------NYFRQLKGSDNNSGSSTVK--LPVKWM
        |.. |.|||.|.|.|.||.||.| ..||||||||||....|...|..||| | |||          | |. ..       .  |  ||..||
--------LCM-KDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEH-------KGGKTMLPIRWM

ALESLHDGLFSEKSNVWSYGVLCWEVFSLGKVPYPG-----LDPIGVVELLDTGGRLQCPHNGA------CSQEIYLVMLSCWSESPNDRPVFSDLVSSI
|.|.. .| |..|| |||.||..||.|..|. ||||     .... |.|....|.|. .|.|.       |..|.| .|..|| | |.||| ||.... .
APECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase AqueK360.AA Tec 104-205 46 2.2e-36 124.66 In-house 154-254 (254) Show / Hide 
Range on Protein: 104-205
Range on HMM: 154-254/254
Sequence Identity: 46% (48 aa)

SST-VKLPVKWMALESLHDGLFSEKSNVWSYGVLCWEVFSLGKVPYPGLDPIGVVELLDTGGRLQCPHNGACSQEIYLVMLSCWSESPNDRPVFSDLVSS
||.  | |||| . | .|   .| || ||..||| |||||.||.||. .. . |||   .| ||  ||   ||..|| .| .||.|.| .|| |..| ..
SSVGTKFPVKWCPPEVFHYSRYSSKSDVWAFGVLMWEVFSCGKMPYENMSNSEVVEHVSQGHRLYRPH--LCSMHIYQIMYHCWHEKPEERPTFQQLLRQ

INA
|  
ITE
Kinase AqueK360.AA Tec 3-81 38 4.2e-26 88.23 In-house 75-142 (254) Show / Hide 
Range on Protein: 3-81
Range on HMM: 75-142/254
Sequence Identity: 38% (31 aa)

FMSRGSLLSYLKKERPNLTVADTSEGDIILNVRKQ--LLSICLQVANGMSYLASERFIHRDLAARNCMIDDNGIIKVADFG
.|..|.||.||....  .              ...  ||..|..|  || || .. ||||||||||| ..|....||.|||
YMEHGCLLNYLREHKHHFQ-------------KNMAILLEMCQDVCEGMAYLERHCFIHRDLAARNCLVGDQCVVKVSDFG
Kinase AqueK360.AA Pkinase 36-203 20 2.4e-12 44.75 Pfam 108-293 (293) Show / Hide 
Range on Protein: 36-203
Range on HMM: 108-293/293
Sequence Identity: 20% (40 aa)

KQLLSICLQVANGMSYLASERFIHRDLAARNCMIDDNGII----KVADFGQSEDIYACNYFRQLKGSDNNSGSSTVKLPVKWMALESLH-DGLFSEKSNV
... ....|.. |. |. |...|||||   |..||.|| |    |..||| .. ..            |||  .|.     .|| | .  .   . |. .
WECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD----------Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDM

WSYGVLCWEVFSLGKVPYPGL----DPIGVVELLDTGGRLQCPHNGACS---------------------QEIYLVMLSCWSESPNDRPVFSDLVSS--I
||.|....|... |. |.||     . .   ....  .. . . .   .                     .|   .. .|.   |..|| . ... .  .
WSCGCILYEMLC-GRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase AqueK360.AA S_TKc 4-207 15 1.3e-08 -50.77 SMART 1-231 (231) Show / Hide 
Range on Protein: 4-207
Range on HMM: 1-231/231
Sequence Identity: 15% (41 aa)

MSRGSLLS-------YLKKERP-NLTVA--------------------------------------DTSEG------DIILNVRK---------QLLSIC
   . ..        |. ...  .  ||                                      .  .|      |.| . ..         .  ...
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIKEHIRREIQILKKHHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPEHARFYM

LQVANGMSYLASERFIHRDLAARNCMIDDNGIIKVADFGQSEDIYACNYFRQLKGSDNNSGSSTVKLPVKWMALESLHDGLFSE-KSNVWSYGVLCWEVF
 |..... |. | ..|||||   | ..|.   ||..||| .  .                  .|.     .|| | |    ..  |. .|| |.. .| .
YQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------------------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEML

SLGKVPYPGLDPIGVVELLDTGGRLQCPHNGACSQEIYLVMLSCWSESPNDRPVFSDLVSSI-----NALI
. |. |.|      . ....  |          |.|    .  |.   |..||   ..  .         .
C-GYPPFP-----QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
SR AqueK360.AA SR 229-326 42 1.2e-43 152.22 SMART 5-118 (118) Show / Hide 
Range on Protein: 229-326
Range on HMM: 5-118/118
Sequence Identity: 42% (48 aa)

DGNSPNEGRLEICING----DWGTVCDDLWTRTNAQVVCRQLGYSIDGAVFLS----RAFFGAGNGSILLDDVVCSGSEDTILQCMHRGFGSHD--CGH-
.||.|.|||.|. .||     ||||||| |. ..|.|||||||..   ..  .    .|.||.|.| |..|.| |.|.|... .|.|.|.|.|.  |.| 
GGNNPCEGRVEVYHNGGGQGQWGTVCDDNWDIRDANVVCRQLGCGGAVSASQTLPATWAHFGQGSGPIWMDNVRCTGTETSLWDCPHWGWGQHNNCCSHN

-----DEDVSVQCS
     .||..| ||
HHRNRQEDAGVVCS
SRCR AqueK360.AA SRCR 228-326 42 6.9e-42 142.52 Pfam 1-112 (112) Show / Hide 
Range on Protein: 228-326
Range on HMM: 1-112/112
Sequence Identity: 42% (48 aa)

LDGNSPNEGRLEICI-NGDWGTVCDD-L-WTRTNAQVVCRQLGY-SIDGAVFLSRAF--FG--AGNGSILLDDVVCSGSEDTILQCMHRGFGS--HD--C
 .|.||.|||.|..  || |||||||   |....|.|||||||. .    .. ..|.  ||  .|.| |..|.| |.|.|... || |.. |   |.  |
VGGSSPCEGRVEVRYHNGQWGTVCDDDGNWDMRDAHVVCRQLGCGGGAVQAWSCCAYAWFGNCPGTGPIWMDNVRCHGNETSLWQCPHSPWGWHRHNPMC

GHD-EDVSVQCS
.|. ||..|.||
SHSREDAGVICS