Gene AqueK380 (A.queenslandica)

AqueK380

Species: A.queenslandica
Alias: AqueK380
External Links:
Annotation:

Classification

Group: TK
Family: Met

Sequence

Name Sequence Type Origin Length Description Download
AqueK380.AA Protein None 932 None Fasta, JSON
AqueK380.kin_dom Protein Kinase Domain None 279 None Fasta, JSON

Protein domain

Protein domains of AqueK380.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
IGc2 AqueK380.AA IGc2 161-225 30 3e-05 24.69 SMART 1-56 (56) Show / Hide 
Range on Protein: 161-225
Range on HMM: 1-56/56
Sequence Identity: 30% (20 aa)

DELTSETVKCTARGFPLPLVRWVKVTSNGGSVTERRENGSSTLVLNDATSGMSGEYYCLAQNMQV
 | .| | .| |.|.| | ..|.|    | ..      ...|| . ..| . ||.| |.|.|   
HEGQSVTLTCPATGNPDPNIHWYK----GQPLP-----WNWTLTIKNVTPEDSGYYTCYARNPWG
IG AqueK380.AA IG 155-245 14 0.00029 21.41 SMART 1-58 (58) Show / Hide 
Range on Protein: 155-245
Range on HMM: 1-58/58
Sequence Identity: 14% (14 aa)

LLNVVMDELTSETVKCTARGFPLPLVRWVKVTSNGGSVTERRENGSSTLVLNDATSGMS---GEYYCLAQNMQVNPPGGKRTVDKA-RSIIVTVR
   |.  |  . | .| .       ..|                    |.. ...   |   |.||| |.            ....  .. .||.
PP-VTVKEGETVTLTC-VS-----QIWWY-------------------LTI-NVQPEDSQQHGTYYCQAT----------HGQYWSIQGTTLTVQ
KR AqueK380.AA KR 401-484 42 1.3e-24 89.05 SMART 1-90 (90) Show / Hide 
Range on Protein: 401-484
Range on HMM: 1-90/90
Sequence Identity: 42% (39 aa)

GSCVRG--NGIGYTGMQVRTRSNHLCQLWMLQTPHKHPMLPSVYVAEL----QNAGYSCRNPGGLGERPWCYTNHPSVR-WEYCNIPSCLN
. |..|  || .| |.  .|.| | || |  |.||.| ..|. .         .  | ||||.|  |.|||||  | || ||||.||.| .
RDCYWGDDNGESYRGTVNTTWSGHPCQRWDSQYPHLHWFYPEWFPCAGQLGLLEHNY-CRNPDGDSEGPWCYTMDPNVRDWEYCDIPQCED
Kringle AqueK380.AA Kringle 403-482 47 6e-22 77.64 Pfam 1-85 (85) Show / Hide 
Range on Protein: 403-482
Range on HMM: 1-85/85
Sequence Identity: 47% (41 aa)

CVRGNGIGYTGMQVRTRSNHLCQLWMLQTPHKHPM-LPSVYVAELQNA---GYSCRNPGGLGER-PWCYT-NHPSVRWEYC-NIPSC
|..||| .| |.  .|.| . || |  ||||.||.  |. . .   .     | |||| |  || ||||| . |.|||||| .||.|
CYHGNGENYRGTWSTTESGRPCQRWDSQTPHRHPFYTPENFPCKGLGEGKHNY-CRNPDGD-ERGPWCYTQTDPRVRWEYCSDIPRC
CCP AqueK380.AA CCP 485-540 25 1.5e-12 48.93 SMART 1-79 (79) Show / Hide 
Range on Protein: 485-540
Range on HMM: 1-79/79
Sequence Identity: 25% (21 aa)

CSELM---VESNEGLSVSY--------SSNSYISTATYSCKNGYSLVG-----------VAARTCLSSGKWSGNP----PYC
|. .    .  |  ...|          . || .|.||||..||.|.|            . .||...  ||. |    | |
CP-PPPHIDPENGYVTCSNSQFTSTFKDTYSYGDTVTYSCNPGYTLIGGRQPEKSQEYHSSTITCQNN--WSPPPWGPLPTC
Sushi AqueK380.AA Sushi 482-540 18 4.1e-09 35.21 Pfam 1-65 (65) Show / Hide 
Range on Protein: 482-540
Range on HMM: 1-65/65
Sequence Identity: 18% (13 aa)

CL-NCSE------LMVESNEGLSVSYSSNSYISTATYSCKNGYSLVGV--AARTCLSSGKWSGNPPY-C
|   ...      ... ....  .... ... |...|.|. || ..|   . .||  .| |.. .|  |
CPFDPPDPNIPHGHVIHTTKWR-CYRN-YQFGSKVYYECDPGYQMMGQGSNTITC--NGQWTPPFPTPC
CCP AqueK380.AA CCP 545-600 23 1.5e-12 48.94 SMART 1-79 (79) Show / Hide 
Range on Protein: 545-600
Range on HMM: 1-79/79
Sequence Identity: 23% (19 aa)

CSELM---IESNEGLSVSY--------SSNTYNSTAIYSCKDGYSLIG-----------IAARICLSNGNWSGNT----PSC
|. .       |  ...|          . .|..|. |||..||.|||            . . |..|  ||. .    |.|
CP-PPPHIDPENGYVTCSNSQFTSTFKDTYSYGDTVTYSCNPGYTLIGGRQPEKSQEYHSSTITCQNN--WSPPPWGPLPTC
Sushi AqueK380.AA Sushi 545-600 20 2.9e-11 42.88 Pfam 1-65 (65) Show / Hide 
Range on Protein: 545-600
Range on HMM: 1-65/65
Sequence Identity: 20% (14 aa)

CS-EL---------MIESNEGLSVSYSSNTYNSTAIYSCKDGYSLIGI--AARICLSNGNWSGNTPS-C
|. .          .| ....  .... . ..|.. |.|..|| . |   . ..|  || |..  |. |
CPFDPPDPNIPHGHVIHTTKWR-CYRN-YQFGSKVYYECDPGYQMMGQGSNTITC--NGQWTPPFPTPC
Pkinase_Tyr AqueK380.AA Pkinase_Tyr 634-912 38 2.8e-109 370.75 Pfam 1-270 (270) Show / Hide 
Range on Protein: 634-912
Range on HMM: 1-270/270
Sequence Identity: 38% (110 aa)

LKILESVGRGEFGIVYRGLIS-VKNRMPQAIAAKTLKGLYSKSD--IDSLLDECVIMMSF-DNLNVLPLIGVCLDLGPA--PYIIMPFMSRGSLLSYLKK
.....  |.|.|| ||.|     .    .  | |.||  .....  ..... |  ||... .. |.. |.|||.| |    .||.|..|  |.||.||.|
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

ERANLTVADTSEEDIILNVRKQLLSICLQVANGMCYLALQRFIHRDLAARNCMIDDNGIIKVADFGLSEKIYSQNYF-RQLEVNNSSPVIKLPVKWMALE
 |         |..  |..   ||..|.|.|.|| ||. ...||||||||||....|...|..||||.  ||.  |  |. .        |||.||||.|
HR---------EDKQPLTMKD-LLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGG------KLPIKWMAPE

SLHDGLFSEKSDVWSYGVLCWEVFSLGRVP-YPGLDPVGVVELL-NTGGRLYSPNNEACSKEIYSLMMSCWSESPNDRPVFSDLVSSI
....| |..||||||.|||.||.|..|. | |||...  |.|..   |.|.  | |  |..|||.||..|| . |.||| ||.... .
CINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPEN--CPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
TyrKc AqueK380.AA TyrKc 634-912 34 3.7e-108 366.53 SMART 1-280 (280) Show / Hide 
Range on Protein: 634-912
Range on HMM: 1-280/280
Sequence Identity: 34% (107 aa)

LKILESVGRGEFGIVYRGLISVKNRMPQAIAAKTLKGLYSKSDIDSLLDECVIMMSF--DNLNVLPLIGVCLDLG------PAPYIIMPFMSRGSLLSYL
.. ..  |.|.||.||.|  .      .  | |.||       .  ...|  ||...  .. |.. |.|||.. |      . ..|.| .|. |.|..||
ITLGKKLGEGAFGEVYKGTWK------IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYL

KKERANLTVADTSEEDIILNVRKQLLSICLQVANGMCYLALQRFIHRDLAARNCMIDDNGIIKVADFGLSEKIYSQ-------NYFRQLEVNNSSPVIK-
.| | .            |.. |.|||.|.|.|.|| ||. ...||||||||||....|...|..||||| .||.         | |. |    .   | 
RKHRPK------------LCM-KDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKE----HKGGKT

-LPVKWMALESLHDGLFSEKSDVWSYGVLCWEVFSLGRVPYPG-----LDPVGVVELLNTGGRLYSPNNEA------CSKEIYSLMMSCWSESPNDRPVF
 ||..|||.|.. .| |..||||||.||..||.|..|  ||||     ...  |.|.. .|.|.  | |        |..|.|..| .|| | |.||| |
MLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTF

SDLVSSI
|.... .
SEIHECF
Kinase AqueK380.AA TK 634-912 22 2.2e-97 327.03 In-house 1-486 (486) Show / Hide 
Range on Protein: 634-912
Range on HMM: 1-486/486
Sequence Identity: 22% (109 aa)

LKILESVGRGEFG---IVYRGLISV----------------------KNRMPQAIAAKTLKGLYSKSDIDSLL-------------DECVIMMSFD----
.....  |.|.||    ||.|.                         |.  ..  | |.||   . |. . ..              |. .|. ..    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-NLNVLPLIGVCLDLG-----------PAPYIIMPFMSRGS----LLSYLKKERA-----------------------------NLTVADTSEEDIILNV
   |.. |.|||.. .           . ..|.| .|. |.    |..||.| |                              ..  .. .... . . 
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITY-SHESNSPC-PEEQ

---------------RKQLLS-------------------ICLQVANGMCYLALQ------RFIHRDLAARNCMIDDNGI-----------IKVADFG--
                |.||.                   .|.|.|.|| ||. .      .|.|||||||||....|..           .|.||||  
DYDDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLS

------LSEKIYS-QNYFRQLEVNNSSP-----------------VIKLPVKWMALESLHDGL---------FSEKSDVWSYGVLCWEVFSLGRVPYPGL
      |. .||| ..| |. .   . |                   |||..||| |.| |.          |..||||||.|||.||.|..|..||.| 
RQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGG

DPV----------GVVELLNTGGR------------LYSPNNEACS--------------KEIYSLMMSCWSESPNDRPVFSDLVSSI
 .            |.|.| .|||            .  |  . |.              .|.| ||..||.. |.||| ||.|.. .
MSNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase AqueK380.AA UTK 634-912 30 8e-85 288.11 In-house 1-296 (296) Show / Hide 
Range on Protein: 634-912
Range on HMM: 1-296/296
Sequence Identity: 30% (94 aa)

LKILESVGRGEFGIVYRGLI-SVKNRMPQ-AIAAKTLK-GLYSKSDID---SLLDECV---IMMSFD-NLNVLPLIGVCLDLGPAPYIIMPFMSRGSLLS
.....  |.|.||.|...    ....|.. . | |... .  .  . .    .. |.    .|. |.   ||| |.|||.. .| ..|.. .|..|.|.|
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEP-WMIVTEYMENGDLRS

YLKKERANLTVADTSEEDIILNVRKQLLSICLQVANGMCYLALQRFIHRDLAARNCMIDDNG-------IIKVADFG---LSEKIY---------SQNYF
|| . | ..      ... .|. . |.|. ....|.|| ||. ..|.||||||||| .....       ..|.||||   .|  ..         ...|.
YLRRHRPTPP-----ACPHWLTLH-QRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYY

RQLEVNNSSPVIKLPVKWMALESLHDG-LFSEKSDVWSYGVLCWEVFSLGRVPYPGLDPVGVVELLNTGGRLYSPNNEACSKEIYSLMMSCWSESPNDRP
..      ... ..|..||| |.| ..  |..||||||.||.|||... ||.||||.  . |.. .  |||.  | ...|. ..| ||..||  .| .||
MA------QHQDRWPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERP

VFSDLVSSI
 | |||. .
DFEDLVQQM
Kinase AqueK380.AA Met 635-906 35 7.2e-84 274.82 In-house 1-271 (271) Show / Hide 
Range on Protein: 635-906
Range on HMM: 1-271/271
Sequence Identity: 35% (104 aa)

KILESVGRGEFGIVYRGLISVKNRMPQAIAAKTLK--GLYSKSDIDSLLDECVIMMSFDNLNVLPLIGVCLDLGP-APYIIMPFMSRGSLLSYLKKERAN
  .. .|.| || ||.|  . .      .| |.|.         |   | | ..|  ||  ||| |||.|||     |... |.|  | |... . .  |
HFDDVIGQGHFGCVYHGMYHDNDGNEHHCACKSLHGERITDIQHISQFLREGIMMKHFDHPNVLSLIGICLDPEGHMPWVVLPYMKHGDLKTFIRNPQNN

LTVADTSEEDIILNVRKQLLSICLQVANGMCYLALQRFIHRDLAARNCMIDDNGIIKVADFGLSEKI-YSQNYFRQLEVNNSSPV-IKLPVKWMALESLH
..|             ..|.. |.||| || |.| |.|.|||||.||||.|   ..|||||||. .. |   |     .  .     .|||||||.|.| 
PCV-------------RDLIEFCHQVAKGMMYMASQKFVHRDLACRNCMLDEHFTVKVADFGLCRDMDYDKEYY----SQMHHTHPARLPVKWMAPECLQ

--------DGL-FSEKSDVWSYGVLCWEVFSLGRVPYPGLDP-VGVVELLNTG--GRLYSPNNEACSKEIY-SLMMSCWSESPNDRPVFS
        .   |. |||||| ||. || .  | .|||  |. . .   | .|   ||  |  | |   .|  .| .||. .| ||| ||
QGVCLGCPTYRQFTTKSDVWSFGVVMWELMTRGAPPYPHVDNWFDITHWLHQGETRRLPQP--EYCPDHLYTDVMLCCWHANPEDRPQFS
Kinase AqueK380.AA TK-Unique 634-912 30 8.5e-83 281.37 In-house 1-294 (294) Show / Hide 
Range on Protein: 634-912
Range on HMM: 1-294/294
Sequence Identity: 30% (93 aa)

LKILESVGRGEFGIVYRGLISVKN---RMPQAIAAKTLKGLYSKSDIDSLLDECVIMMSFD-NLNVLPLIGVCLDLGPAPYIIMPFMSRGSLLSYLKKER
|......|.|.|| |.|| .. ..     .. .| |.||   .. | . .|.|  .|.. .   |.. ..|.| . .  ..|||.....|.|..||.. |
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR

---------ANLT-VADTSEEDIILN-VR-KQLLSICLQVANGMCYLAL--QRFIHRDLAARNCMIDDNGIIKVADFGLSEKIYSQNYFRQLEVNNSSPV
         .||   ... ...  .. .  |.|.... |.|.|| |||   ....||||.|||... .....|..|||.....|        .....   
PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYT-----NGVYSMMCSQ

IKLPVKWMALESLH--DGLF-SEKSDVWSYGVLCWEVFSLGRVPYPGLDPVGVVELLNTGGRLYSPNNEAC-SKEIYSLMMSCWSESPNDRPVFSDLVSS
 ..|..|||.|||   .| . ..||||||.||| ||.|.||  ||||...  ..|..  | |.  |..  | |.|.|.|| |||...| .|| |..... 
GRIPIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYRMPQPEH--CCSHEMYNLMKSCWQWEPEERPSFRQIKHR

I
.
L
Kinase AqueK380.AA Axl 634-910 39 4.6e-74 252.38 In-house 1-267 (267) Show / Hide 
Range on Protein: 634-910
Range on HMM: 1-267/267
Sequence Identity: 39% (111 aa)

LKILESVGRGEFGIVYRGLISVKNRMPQAIAAKTLK-GLYSKSDIDSLLDECVIMMSFDNLNVLPLIGVCLDLG-----PAPYIIMPFMSRGSLLSYLKK
. .   .|.|||| |  | .       . .| |..|    ..|.|.  | | . |  ||  ||. |||||. .      |.| .|.|||  | | ..|  
FVLGKMLGEGEFGSVMEGQLKQEDGSFVKVAVKMMKIDICTQSEIEEFLSEAACMKEFDHPNVMRLIGVCIQMSERQRIPKPMVILPFMKHGDLHTFLLY

ERANLTVADTSEEDIILNVRKQLLSICLQVANGMCYLALQRFIHRDLAARNCMIDDNGIIKVADFGLSEKIYSQNYFRQLEVNNSSPVIKLPVKWMALES
 | .       .. . | . . |.   . .| || ||. ..||||||||||||. ..  . ||||||| ||||  |.||        . |.||||.|.||
SRLG-------DQPFYLPL-QMLVKFMVDIACGMEYLSNRNFIHRDLAARNCMLREDMTVCVADFGLSKKIYSGDYYRQGC------IAKMPVKWIAIES

LHDGLFSEKSDVWSYGVLCWEVFSLGRVPYPGLDPVGVVELLNTGGRLYSPNNEACSKEIYSLMMSCWSESPNDRPVFSDLVS
| | ..  |||||..||  ||.   |. ||||..   . . |  | ||  |  | |  |.| || .||.  | ||| || |  
LADRVYTSKSDVWAFGVTMWEIMTRGQTPYPGVENHEMYDYLIHGHRLKQP--EDCMDELYDLMYQCWEADPKDRPSFSVLRE
Kinase AqueK380.AA Tec 634-914 36 1.2e-69 237.67 In-house 1-254 (254) Show / Hide 
Range on Protein: 634-914
Range on HMM: 1-254/254
Sequence Identity: 36% (105 aa)

LKILESVGRGEFGIVYRGLISVKNRMPQAIAAKTLK-GLYSKSDIDSLLDECVIMMSFDNLNVLPLIGVCLDLGPAPYIIMPFMSRGSLLSYLKKERANL
|.... .|.| ||.| .|    | |    .| |..| |  |  |    ..|  .||     .   | |||.   |  ||.  .|..|.||.||....  .
LTFMKELGSGQFGVVHLG----KWRHQYDVAIKMIKEGSMSEED---FIEEAKVMMKLSHPKLVQLYGVCSQQRPI-YIVTEYMEHGCLLNYLREHKHHF

TVADTSEEDIILNVRKQ--LLSICLQVANGMCYLALQRFIHRDLAARNCMIDDNGIIKVADFGLSEKIYSQNYFRQLEVNNSSPVIKLPVKWMALESLHD
              ...  ||..|..|  || ||  . ||||||||||| ..|....||.|||..  .    |        ||   | |||| . | .| 
Q-------------KNMAILLEMCQDVCEGMAYLERHCFIHRDLAARNCLVGDQCVVKVSDFGMTRYVLDDQYT-------SSVGTKFPVKWCPPEVFHY

GLFSEKSDVWSYGVLCWEVFSLGRVPYPGLDPVGVVELLNTGGRLYSPNNEACSKEIYSLMMSCWSESPNDRPVFSDLVSSINA
  .| |||||..||| |||||.|..||. .. . |||   .| ||| |  . ||..||  | .||.|.| .|| |..| ..|  
SRYSSKSDVWAFGVLMWEVFSCGKMPYENMSNSEVVEHVSQGHRLYRP--HLCSMHIYQIMYHCWHEKPEERPTFQQLLRQITE
Kinase AqueK380.AA Src 634-912 36 2e-69 235.02 In-house 1-255 (255) Show / Hide 
Range on Protein: 634-912
Range on HMM: 1-255/255
Sequence Identity: 36% (103 aa)

LKILESVGRGEFGIVYRGLISVKNRMPQAIAAKTLKGLYSKSDIDSLLDECVIMMSFDNLNVLPLIGVCLDLGPAPYIIMPFMSRGSLLSYLKKERANLT
.| ..  |.| || |. |.   ..... |.  ||||      . . .| |  || ...  ... |  || .  |  ||.  .||.|||| ||||      
IKLCRKLGQGQFGEVWMGYW--NGNTKVAV--KTLKPGT--MSPEAFLQEAQIMKKLRHEKLVQLYAVCSQEEPI-YIVTEYMSHGSLLDYLKK------

VADTSEEDIILNVRKQLLSICLQVANGMCYLALQRFIHRDLAARNCMIDDNGIIKVADFGLSEKIY--SQNY-FRQLEVNNSSPVIKLPVKWMALESLHD
    ..|   |... ||...  |||.||.||  ...|||||||||  ...| . |||||||   |     .|  |.          |.|.||.| | .. 
----DGEGRHLHLP-QLIDMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLARLIKEDDDEYCARH--------GAKFPIKWTAPEAINY

GLFSEKSDVWSYGVLCWEVFSLGRVPYPGLDPVGVVELLNTGGRLYSPNNEACSKEIYS-LMMSCWSESPNDRPVFSDLVSSI
| |. ||||||.|.| .|... ||||||| .   |.. .  | |.  | |  | .|.|  .|. || ..| .|| |  | .  
GRFTIKSDVWSFGILLTEIVTYGRVPYPGMTNHEVLQQVERGYRMPCPHN--CPDELYEQIMLQCWHKDPEQRPTFEYLQWFL
Kinase AqueK380.AA ALK 634-914 37 4.5e-68 232.46 In-house 1-273 (273) Show / Hide 
Range on Protein: 634-914
Range on HMM: 1-273/273
Sequence Identity: 37% (107 aa)

LKILESVGRGEFGIVYRGLISV--KNRMPQAIAAKTLKGLYSKSDIDSLLDECVIMMSFDNLNVLPLIGVCLDLGPAPYIIMPFMSRGSLLSYLKKERAN
.. .   |.| || || |. |       | ..| |||. . |. |    . |  ||  |.  ||  .||.|..  |  .|.  .|. | ..|.|.  | .
ITLVRALGHGAFGEVYMGQYSHMPGDSVPMQVAMKTLPEDCSQQDEEDFCMEALIMGKFNHQNVVRCIGICFQKQPY-MIVLEYMEGGDMKSFLRECRPH

LTVADTSEE--DIILNVRKQLLSICLQVANGMCYLALQRFIHRDLAARNCMIDDNG---IIKVADFGLSEKI-YSQNYFRQLEVNNSSPVIKLPVKWMAL
       .|     . . | || .|. || |  ||  ..||||| |||||     |   . |.|||| .  | |   |.|            .|||||  
-------PESLQPSQLTMKDLLQCCCDVAQGCHYLEENHFIHRDIAARNCLLTCKGPGRVAKIADFGMARDITYRADYYRKGG------RAMMPVKWMPP

ESLHDGLFSEKSDVWSYGVLCWEVFSLGRVPYPGLDPVGVVELLNTGGRLYSPNNEACSKEIYSLMMSCWSESPNDRPVFSDLVSSINA
| . ||.|  |.||||.||||||.||||..||||     | |.. .|||. .| |  |   .| .|  ||   | ||| | ... .| .
EAFMDGIFTSKTDVWSFGVLCWEIFSLGYMPYPGRHNQEVMEFVTEGGRMDPPRN--CPQPVYRIMTQCWQHQPEDRPKFVTILEHIQY
Kinase AqueK380.AA InsR 634-914 33 2.3e-64 215.06 In-house 1-278 (278) Show / Hide 
Range on Protein: 634-914
Range on HMM: 1-278/278
Sequence Identity: 33% (97 aa)

LKILESVGRGEFGIVYRG-LISVKNRMPQA---IAAKTLKGLYSKSDIDSLLDECVIMMSFDNLNVLPLIGVCLDLGPAPYIIMPFMSRGSLLSYLKKER
. ..   | | || || | . ..   .. .   .| ||..   |  .    | |  .|  |.  .|  | |||    |. |..| .| .| | |||   |
IVLIRECGQGSFGMVYEGIAKGIVPDEEWRFGRCAIKTVNENASMRERIEFLNEASVMKEFNCHHVVRLLGVCSRGQPM-YVVMEMMTYGDLKSYLRSRR

ANLTVADTSEEDII----LNVRKQLLSICLQVANGMCYLALQRFIHRDLAARNCMIDDNGIIKVADFGLSEKIYSQNYFRQLEVNNSSPVIKLPVKWMAL
         . ...       . |...   ... || |||   |.|||||.||||... . .|..|||.   ||   | |       .   .||| ||| 
PEEEF---NNPGCNRNQHVPCLDQMHQMAAEICDGMAYLAAKKFVHRDLACRNCMVNHDFTVKIGDFGMTRDIYEHDYYRK------GGKGMLPVRWMAP

ESLHDGLFSEKSDVWSYGVLCWEVFSLGRVPYPGLDPVGVVELL-NTGGRLYSPNNEACSKEIYSLMMSCWSESPNDRPVFSDLVSSINA
||| || |. .|||||.||. ||. .||  || ||    | .     |. |  |  | |..  . ||| ||  .| .|| | |.....  
ESLKDGVFTTHSDVWSFGVVLWEMVTLGEQPYQGLSNEQVLKYIGMDGNVLRPP--ENCPEYWQELMMMCWQYQPKMRPTFLDIIHYLCD
Kinase AqueK380.AA Csk 634-912 36 1.2e-63 216.05 In-house 1-251 (251) Show / Hide 
Range on Protein: 634-912
Range on HMM: 1-251/251
Sequence Identity: 36% (101 aa)

LKILESVGRGEFGIVYRGLISVKNRMPQAIAAKTLKGLYSKSDIDSLLDECVIMMSFDNLNVLPLIGVCLDLGPAPYIIMPFMSRGSLLSYLKKERANLT
|...|..| |||| |  |    .||    .| | .|.  .   ....|.|  .|      |   |||| |. .   ||.| .||.|.|. ||        
LHLGECIGHGEFGDVMQG--EYQNRK---VAVKCIKCD-GNGMAQAFLAEASVMTQLRHPNLVQLIGVILHQKNHLYIVMEYMSKGNLVDYLR-------

VADTSEEDIILNVRKQLLSICLQVANGMCYLALQRFIHRDLAARNCMIDDNGIIKVADFGLSEKIYSQNYFRQLEVNNSSPVIKLPVKWMALESLHDGLF
    | .  ... |.|||   . |..|||||    |.||||||||  ...  . || ||||     ..    |..   |.   |.|.|| | | |  . |
----SRGRHVIT-RRQLLKFAMDVCEGMCYLEQKKFVHRDLAARNILVSEDCVAKVSDFGL-----AKEECSQQDDSTSG---KFPIKWTAPEALRHKKF

SEKSDVWSYGVLCWEVFSLGRVPYPGLDPVGVVELLNTGGRLYSPNNEACSKEIYSLMMSCWSESPNDRPVFSDLVSSI
| ||||||.|.| ||..| |||||| .    ||.    | |  .|  | |  ..| .| .||  .| .|| |  ...  
STKSDVWSFGILLWEIYSFGRVPYPRIPLKDVVKHVEKGYRMEAP--EGCPPHVYKVMKQCWHLNPAKRPTFRQVREQL
Kinase AqueK380.AA S_TKc 634-916 19 4.5e-28 100.49 SMART 1-231 (231) Show / Hide 
Range on Protein: 634-916
Range on HMM: 1-231/231
Sequence Identity: 19% (59 aa)

LKILESVGRGEFGIVYRGLISVKNRM-PQAIAAKTLKGLYSKSDIDSLLDECVIMMSFDNLNVLPLIGVCLDLGPAPYIIMPFMSR--GSLLSYLKKERA
 .||. .|.| || ||.    ....   .  | | .|        .... |  |... .  |.  |..|. |     |..| ...   |.|..|.|| . 
YEILRKIGKGAFGKVYK----CRHKKTGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIKKRGR

N-----LTVADTSEEDIILNVRKQLLSICLQVANGMCYLALQRFIHRDLAARNCMIDDNGIIKVADFGLSEKIYSQNYFRQLEVNNSSPVIKLPVKWMAL
.     ..  ..              ... |..... |.  ...|||||   | ..|.   ||..||||. ..                 .     .|| 
HGLRFPFPE-HAR-------------FYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---------------TTFCGTPWYMAP

ESLHDGLFSE-KSDVWSYGVLCWEVFSLGRVPYPGLDPVGVVELLNTGGRLYSPNNEACSKEIYSLMMSCWSESPNDRPVFSDLVSSI-----NALI
| |    ..  |.|.|| |.. .| .. |. |.|      . ....  |          |.|  .... |.   |..||   ..  .         .
EVL---GYGKCKCDWWSCGCILYEMLC-GYPPFP-----QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK380.AA Pkinase 634-806 23 1.5e-16 59.59 Pfam 1-166 (293) Show / Hide 
Range on Protein: 634-806
Range on HMM: 1-166/293
Sequence Identity: 23% (44 aa)

LKILESVGRGEFGIVYRGLISVKNRMPQAIAAKTLKGLYSKSDID--SLL-DECVIMMSFDNLNVLPLIGVCLDLGPAPYIIMPFMSRG----SLLSYLK
..|.. .|.| || ||..     ..     | |..|    ||. |   ..  |. || ...  |.. |.... | .. .|..|...  |    .| .|..
YHIGRKIGSGSFGCVYKCHHKGTGK---IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED-KDHIYMVMEYCEGGLYVMDLFDYIS

KERANLTVADTSEEDIIL--NVRKQLLSICLQVANGMCYLALQRFIHRDLAARNCMIDDNGII----KVADFGLSEKIYSQNYFRQ
            ...  .     ... ....|.. |. |.  ...|||||   |..||.|| |    |..||||.....   | ..
T-----------WRHGCFYFS-EWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD---Y-NN
Kinase AqueK380.AA Pkinase 834-912 17 1.4e-07 27.88 Pfam 190-293 (293) Show / Hide 
Range on Protein: 834-912
Range on HMM: 190-293/293
Sequence Identity: 17% (19 aa)

SEKSDVWSYGVLCWEVFSLGRVPYPGL----DPVGVVELLNTGGR--LYSPNNEACS-------------------KEIYSLMMSCWSESPNDRPVFSDL
. |.|.||.|....|... || |.||     . .   ....  ..  | ..  . ||                   .|  ... .|.   |..|| . ..
GPKVDMWSCGCILYEMLC-GRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQI

VSS--I
. .  .
LQHPWF