AqueK382

Species: A.queenslandica
Alias: AqueK382
External Links:
Annotation:

Classification

Group: TK
Family: Met

Sequence

Name Sequence Type Origin Length Description Download
AqueK382.AA Protein None 713 None Fasta, JSON
AqueK382.kin_dom Protein Kinase Domain None 281 None Fasta, JSON

Protein domain

Protein domains of AqueK382.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
SR AqueK382.AA SR 5-105 34 2.2e-37 131.46 SMART 1-118 (118) Show / Hide
Range on Protein: 5-105
Range on HMM: 1-118/118
Sequence Identity: 34% (41 aa)

LKLVNGKT-TIGRLEICINN----EWGTVCDDGWTHTNAEVVCRQLGYSTIGAQYFN----GKYFDAENMSIFLDDVVCLGSEDNILQCNHSTIGFHN--
. ||.| .   ||.|. .|.    .|||||||.|. ..|.|||||||...  . . .    . .| . .  | .|.| | |.|... .| |...| ||  
VRLVGGNNPCEGRVEVYHNGGGQGQWGTVCDDNWDIRDANVVCRQLGCGGAVSASQTLPATWAHFGQGSGPIWMDNVRCTGTETSLWDCPHWGWGQHNNC

CSH------SNDVSVQCF
|||      ..|..| | 
CSHNHHRNRQEDAGVVCS

SRCR AqueK382.AA SRCR 8-105 41 1.4e-32 111.3 Pfam 1-112 (112) Show / Hide
Range on Protein: 8-105
Range on HMM: 1-112/112
Sequence Identity: 41% (46 aa)

VNGKT-TIGRLEICI-NNEWGTVCDD-G-WTHTNAEVVCRQLGYSTIGAQY-FNGKY--FD--AENMSIFLDDVVCLGSEDNILQCNHSTIGF--HN--C
|.|..   ||.|..  |..||||||| | |. ..|.|||||||.   ..|  ... |  |   . .  | .|.| | |.|... ||.||  |   ||  |
VGGSSPCEGRVEVRYHNGQWGTVCDDDGNWDMRDAHVVCRQLGCGGGAVQAWSCCAYAWFGNCPGTGPIWMDNVRCHGNETSLWQCPHSPWGWHRHNPMC

SHS-NDVSVQCF
||| .|..|.| 
SHSREDAGVICS

Pkinase_Tyr AqueK382.AA Pkinase_Tyr 409-689 40 2.2e-116 394.8 Pfam 1-270 (270) Show / Hide
Range on Protein: 409-689
Range on HMM: 1-270/270
Sequence Identity: 40% (116 aa)

ISVQETVGQGEFGIVYRGVMT-IENQMPQPVAVKTLKGFYSKSD--IDSLLDECIIMMSF-DNLNVLPLIGVCLDLGPA--PYIIMPFMSRGSLLSYLKK
|.  .. |.|.|| ||.|...  . .  .|||||.||  .....  ..... |  ||... .. |.. |.|||.| |    .||.|..|  |.||.||.|
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

ERPNLTVADTSEEDIILNVRKQLLSICLQVGNGMCYLASQRFIHRDLAARNCMIDDDGIIKVADFGLSEDIYSQNYF-RQLEGSKDSSSSPVKLPLKWMA
 |         |..  |..   ||..|.|. .|| ||.|...||||||||||........|..||||. |||.  |  |. .|.        ||| ||||
HR---------EDKQPLTMKD-LLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGG--------KLPIKWMA

LESIHDGLFSEKSDVWSYGVLCWEVFSLGRVP-YPGLDPVGVVELL-NTGGRLYTPNNEACSKEIYSLMTSCWSESPDDRPVFSDLVSSI
.|.|..| |..||||||.|||.||.|..|. | |||...  |.|..   |.|.  | |  |..|||.||..|| . |.||| ||.... .
PECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPEN--CPDEIYDLMKQCWHYDPEDRPTFSEIHEQL

TyrKc AqueK382.AA TyrKc 409-689 36 8.3e-114 385.31 SMART 1-280 (280) Show / Hide
Range on Protein: 409-689
Range on HMM: 1-280/280
Sequence Identity: 36% (113 aa)

ISVQETVGQGEFGIVYRGVMTIENQMPQPVAVKTLKGFYSKSDIDSLLDECIIMMSF--DNLNVLPLIGVCLDLG------PAPYIIMPFMSRGSLLSYL
|.  .. | |.||.||.|...      ..||||.||       .  ...|  ||...  .. |.. |.|||.. |      . ..|.| .|. |.|..||
ITLGKKLGEGAFGEVYKGTWK------IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYL

KKERPNLTVADTSEEDIILNVRKQLLSICLQVGNGMCYLASQRFIHRDLAARNCMIDDDGIIKVADFGLSEDIYSQ-------NYFRQLE--GSKDSSSS
.| ||.            |.. |.|||.|.|. .|| ||.|...||||||||||........|..||||| |||.         | |. |  |.|.    
RKHRPK------------LCM-KDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKT----

PVKLPLKWMALESIHDGLFSEKSDVWSYGVLCWEVFSLGRVPYPG-----LDPVGVVELLNTGGRLYTPNNEA------CSKEIYSLMTSCWSESPDDRP
   ||..|||.|.| .| |..||||||.||..||.|..|  ||||     ...  |.|.. .|.|.  | |        |..|.|..|..|| | |.|||
--MLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRP

VFSDLVSSI
 ||.... .
TFSEIHECF

Kinase AqueK382.AA TK 409-689 23 1.3e-100 338.01 In-house 1-486 (486) Show / Hide
Range on Protein: 409-689
Range on HMM: 1-486/486
Sequence Identity: 23% (114 aa)

ISVQETVGQGEFG---IVYRGVMTIEN----------------------QMPQPVAVKTLKGFYSKSDIDSLL---------------DECIIMMS---F
| . .. |.|.||    ||.| .  .|                      . ..|||||.||   . |. . ..                | . ||.   .
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

DNLNVLPLIGVCLDLG-----------PAPYIIMPFMSRGS----LLSYLKKERP-----------------------------NLTVADTSEEDIILNV
.  |.. |.|||.. .           . ..|.| .|. |.    |..||.| ||                             ..  .. .... . . 
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITY-SHESNSPC-PEEQ

---------------RKQLLS-------------------ICLQVGNGMCYLASQ------RFIHRDLAARNCMIDDDGI-----------IKVADFG--
                |.||.                   .|.|. .|| ||.|.      .|.|||||||||.......           .|.||||  
DYDDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLS

------LSEDIYS-QNYFRQL---------------EGSKDSSSSPVKLPLKWMALESIHDGL---------FSEKSDVWSYGVLCWEVFSLGRVPYPGL
      |. |||| ..| |.                . .   ..|  |||..||| |.. |.          |..||||||.|||.||.|..|..||.| 
RQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGG

DPV----------GVVELLNTGGR------------LYTPNNEACS--------------KEIYSLMTSCWSESPDDRPVFSDLVSSI
 .            |.|.| .|||            .  |  . |.              .|.| ||..||.. |.||| ||.|.. .
MSNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL

Kinase AqueK382.AA Met 410-683 36 2.4e-89 293.09 In-house 1-271 (271) Show / Hide
Range on Protein: 410-683
Range on HMM: 1-271/271
Sequence Identity: 36% (107 aa)

SVQETVGQGEFGIVYRGVMTIENQMPQPVAVKTLK--GFYSKSDIDSLLDECIIMMSFDNLNVLPLIGVCLDLGP-APYIIMPFMSRGSLLSYLKKERPN
 . . .||| || ||.| .. . .   ..|.|.|.         |   | | |.|  ||  ||| |||.|||     |... |.|  | |... . .  |
HFDDVIGQGHFGCVYHGMYHDNDGNEHHCACKSLHGERITDIQHISQFLREGIMMKHFDHPNVLSLIGICLDPEGHMPWVVLPYMKHGDLKTFIRNPQNN

LTVADTSEEDIILNVRKQLLSICLQVGNGMCYLASQRFIHRDLAARNCMIDDDGIIKVADFGLSEDI-YSQNYFRQLEGSKDSSSSPVKLPLKWMALESI
..|             ..|.. |.||  || |.|||.|.|||||.||||.| . ..|||||||. |. |   |      |  .   | .||.||||.|. 
PCV-------------RDLIEFCHQVAKGMMYMASQKFVHRDLACRNCMLDEHFTVKVADFGLCRDMDYDKEYY-----SQMHHTHPARLPVKWMAPECL

H--------DGL-FSEKSDVWSYGVLCWEVFSLGRVPYPGLDP-VGVVELLNTG--GRLYTPNNEACSKEIY-SLMTSCWSESPDDRPVFS
         .   |. |||||| ||. || .  | .|||  |. . .   | .|   ||  |  | |   .|  .| .||. .| ||| ||
QQGVCLGCPTYRQFTTKSDVWSFGVVMWELMTRGAPPYPHVDNWFDITHWLHQGETRRLPQP--EYCPDHLYTDVMLCCWHANPEDRPQFS

Kinase AqueK382.AA TK-Unique 409-689 32 4e-88 299.08 In-house 1-294 (294) Show / Hide
Range on Protein: 409-689
Range on HMM: 1-294/294
Sequence Identity: 32% (99 aa)

ISVQETVGQGEFGIVYRGVMTIEN---QMPQPVAVKTLKGFYSKSDIDSLLDECIIMMSFD-NLNVLPLIGVCLDLGPAPYIIMPFMSRGSLLSYLKKER
. |....|.|.|| |.|| ..  .     .. ||||.||   .. | . .|.|  .|.. .   |.. ..|.| . .  ..|||.....|.|..||.. |
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR

P---------NLT-VADTSEEDIILN-VR-KQLLSICLQVGNGMCYLAS--QRFIHRDLAARNCMIDDDGIIKVADFGLSEDIYSQNYFRQLEGSKDSSS
|         ||   ... ...  .. .  |.|.... |. .|| ||||  ....||||.|||... .|...|..|||...|.|        .|  ... 
PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYT-------NGVYSMMC

SPVKLPLKWMALESIH--DGLF-SEKSDVWSYGVLCWEVFSLGRVPYPGLDPVGVVELLNTGGRLYTPNNEAC-SKEIYSLMTSCWSESPDDRPVFSDLV
|  ..|..|||.||.   .| . ..||||||.||| ||.|.||  ||||...  ..|..  | |.  |..  | |.|.|.|| |||...|..|| |....
SQGRIPIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYRMPQPEH--CCSHEMYNLMKSCWQWEPEERPSFRQIK

SSI
. .
HRL

Kinase AqueK382.AA UTK 409-689 31 2.1e-85 290.03 In-house 1-296 (296) Show / Hide
Range on Protein: 409-689
Range on HMM: 1-296/296
Sequence Identity: 31% (99 aa)

ISVQETVGQGEFGIVYRGVMT-IENQMPQ-PVAVKTLKGFYSKSD----ID---SLLDECI---IMMSFD-NLNVLPLIGVCLDLGPAPYIIMPFMSRGS
.   .. |||.||.|...  | . ..|..  ||||...   ...|     .    .. |.    .|. |.   ||| |.|||.. .| ..|.. .|..|.
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQ---HHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEP-WMIVTEYMENGD

LLSYLKKERPNLTVADTSEEDIILNVRKQLLSICLQVGNGMCYLASQRFIHRDLAARNCMIDDDG-------IIKVADFG---LSEDIY---------SQ
|.||| . ||..      ... .|. . |.|. .... .|| ||.|..|.||||||||| .....       ..|.||||   .| ...         ..
LRSYLRRHRPTPP-----ACPHWLTLH-QRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWES

NYFRQLEGSKDSSSSPVKLPLKWMALESIHDG-LFSEKSDVWSYGVLCWEVFSLGRVPYPGLDPVGVVELLNTGGRLYTPNNEACSKEIYSLMTSCWSES
.|...        ..  ..|..||| |.. ..  |..||||||.||.|||... ||.||||.  . |.. .  |||.  | ...|. ..| ||..||  .
YYYMA--------QHQDRWPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYD

PDDRPVFSDLVSSI
|..|| | |||. .
PQERPDFEDLVQQM

Kinase AqueK382.AA Axl 409-687 38 7.9e-73 248.27 In-house 1-267 (267) Show / Hide
Range on Protein: 409-687
Range on HMM: 1-267/267
Sequence Identity: 38% (111 aa)

ISVQETVGQGEFGIVYRGVMTIENQMPQPVAVKTLK-GFYSKSDIDSLLDECIIMMSFDNLNVLPLIGVCLDLG-----PAPYIIMPFMSRGSLLSYLKK
. .  ..|.|||| |  | .  |    . ||||..|    ..|.|.  | | . |  ||  ||. |||||. .      |.| .|.|||  | | ..|  
FVLGKMLGEGEFGSVMEGQLKQEDGSFVKVAVKMMKIDICTQSEIEEFLSEAACMKEFDHPNVMRLIGVCIQMSERQRIPKPMVILPFMKHGDLHTFLLY

ERPNLTVADTSEEDIILNVRKQLLSICLQVGNGMCYLASQRFIHRDLAARNCMIDDDGIIKVADFGLSEDIYSQNYFRQLEGSKDSSSSPVKLPLKWMAL
 |         .. . | . . |.   . .  || ||....||||||||||||. .|  . |||||||  |||  |.||   .        |.| ||.|.
SR-------LGDQPFYLPL-QMLVKFMVDIACGMEYLSNRNFIHRDLAARNCMLREDMTVCVADFGLSKKIYSGDYYRQGCIA--------KMPVKWIAI

ESIHDGLFSEKSDVWSYGVLCWEVFSLGRVPYPGLDPVGVVELLNTGGRLYTPNNEACSKEIYSLMTSCWSESPDDRPVFSDLVS
||. | ..  |||||..||  ||.   |. ||||..   . . |  | ||  |  | |  |.| || .||.  | ||| || |  
ESLADRVYTSKSDVWAFGVTMWEIMTRGQTPYPGVENHEMYDYLIHGHRLKQP--EDCMDELYDLMYQCWEADPKDRPSFSVLRE

Kinase AqueK382.AA Src 409-689 37 9e-69 232.77 In-house 1-255 (255) Show / Hide
Range on Protein: 409-689
Range on HMM: 1-255/255
Sequence Identity: 37% (106 aa)

ISVQETVGQGEFGIVYRGVMTIENQMPQPVAVKTLKGFYSKSDIDSLLDECIIMMSFDNLNVLPLIGVCLDLGPAPYIIMPFMSRGSLLSYLKKERPNLT
|   .  ||| || |. |.    ...  .|||||||      . . .| |  || ...  ... |  || .  |  ||.  .||.|||| ||||      
IKLCRKLGQGQFGEVWMGYW--NGNT--KVAVKTLKPGT--MSPEAFLQEAQIMKKLRHEKLVQLYAVCSQEEPI-YIVTEYMSHGSLLDYLKK------

VADTSEEDIILNVRKQLLSICLQVGNGMCYLASQRFIHRDLAARNCMIDDDGIIKVADFGLSEDIY--SQNY-FRQLEGSKDSSSSPVKLPLKWMALESI
    ..|   |... ||...  || .||.|| |...|||||||||  .... . |||||||   |     .|  |.            |.| ||.| | |
----DGEGRHLHLP-QLIDMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLARLIKEDDDEYCARH----------GAKFPIKWTAPEAI

HDGLFSEKSDVWSYGVLCWEVFSLGRVPYPGLDPVGVVELLNTGGRLYTPNNEACSKEIYS-LMTSCWSESPDDRPVFSDLVSSI
. | |. ||||||.|.| .|... ||||||| .   |.. .  | |.  | |  | .|.|  .|. || ..|..|| |  | .  
NYGRFTIKSDVWSFGILLTEIVTYGRVPYPGMTNHEVLQQVERGYRMPCPHN--CPDELYEQIMLQCWHKDPEQRPTFEYLQWFL

Kinase AqueK382.AA FGFR 409-689 33 1.5e-68 232.79 In-house 1-293 (293) Show / Hide
Range on Protein: 409-689
Range on HMM: 1-293/293
Sequence Identity: 33% (103 aa)

ISVQETVGQGEFGIVYRGVMT-IENQ---MPQPVAVKTLKGFYSKSDIDSLLDECIIM-MSFDNLNVLPLIGVCLDLGPAPYIIMPFMSRGSLLSYLKKE
 .. .. | | || | ..    |...       |||| ||   .  |. .|  |  .| |   . |.. |.|.|   || .|.|  . ..| |  .|.. 
LTLGKMLGEGCFGQVWMAEAKGIDCDRPEKEITVAVKMLKMNHTDKDLSDLVSEMEMMKMIGKHKNIINLLGCCTQEGP-LYVIVEYCHHGNLRDFLRAR

RPNLTVADTSEE-------DIILNV----------RKQLLSICLQVGNGMCYLASQRFIHRDLAARNCMIDDDGIIKVADFGLSEDIYSQNYFRQLEGSK
||    .. . .        .   .           |.| |.  ||  || ||||.. |||||||||  . || ..|..||||. || .  |.|      
RPPGMDYKKDSQEYTDYKPRKPEQQDDIELIPNLTQKDLVSCAYQVARGMEYLASRKCIHRDLAARNVLVTDDYVMKICDFGLARDIHCIDYYRK-----

DSSSSPVKLPLKWMALESIHDGLFSEKSDVWSYGVLCWEVFSLGRVPYPGLD-PVGVVELLNTGGRLYTPNNEACSKEIYSLMTSCWSESPDDRPVFSDL
    .   || ||||.|.  |  .  .||||||||| ||.. .|  |||.        ..| .| |.  | |  ||.||| .| .|| ..|..|| |  |
---TTNGRLPIKWMAPEALFDRVYTHQSDVWSYGVLLWEIMTYGGQPYPHIPSVEELYKYLKEGHRMEKPHN--CSQEIYHMMCQCWHFKPCQRPTFKQL

VSSI
| ..
VEYL

Kinase AqueK382.AA Tec 409-691 35 2.1e-68 233.6 In-house 1-254 (254) Show / Hide
Range on Protein: 409-691
Range on HMM: 1-254/254
Sequence Identity: 35% (102 aa)

ISVQETVGQGEFGIVYRGVMTIENQMPQPVAVKTLK-GFYSKSDIDSLLDECIIMMSFDNLNVLPLIGVCLDLGPAPYIIMPFMSRGSLLSYLKKERPNL
.   . .|.| ||.| .|  . . .    ||.|..| |  |  |    ..|  .||     .   | |||.   |  ||.  .|..|.||.||....  .
LTFMKELGSGQFGVVHLGKWRHQYD----VAIKMIKEGSMSEED---FIEEAKVMMKLSHPKLVQLYGVCSQQRPI-YIVTEYMEHGCLLNYLREHKHHF

TVADTSEEDIILNVRKQ--LLSICLQVGNGMCYLASQRFIHRDLAARNCMIDDDGIIKVADFGLSEDIYSQNYFRQLEGSKDSSSSPVKLPLKWMALESI
              ...  ||..|..|  || || .. ||||||||||| ..|....||.|||..  .    |          ||.  | | || . |  
Q-------------KNMAILLEMCQDVCEGMAYLERHCFIHRDLAARNCLVGDQCVVKVSDFGMTRYVLDDQYT---------SSVGTKFPVKWCPPEVF

HDGLFSEKSDVWSYGVLCWEVFSLGRVPYPGLDPVGVVELLNTGGRLYTPNNEACSKEIYSLMTSCWSESPDDRPVFSDLVSSINT
|   .| |||||..||| |||||.|..||. .. . |||   .| ||| |  . ||..||  | .||.|.|..|| |..| ..|  
HYSRYSSKSDVWAFGVLMWEVFSCGKMPYENMSNSEVVEHVSQGHRLYRP--HLCSMHIYQIMYHCWHEKPEERPTFQQLLRQITE

Kinase AqueK382.AA ALK 409-691 37 2.1e-68 233.6 In-house 1-273 (273) Show / Hide
Range on Protein: 409-691
Range on HMM: 1-273/273
Sequence Identity: 37% (110 aa)

ISVQETVGQGEFGIVYRGVMTI--ENQMPQPVAVKTLKGFYSKSDIDSLLDECIIMMSFDNLNVLPLIGVCLDLGPAPYIIMPFMSRGSLLSYLKKERPN
|      |.| || || |  .       | .||.|||.   |. |    . |  ||  |.  ||  .||.|..  |  .|.  .|. | ..|.|.  ||.
ITLVRALGHGAFGEVYMGQYSHMPGDSVPMQVAMKTLPEDCSQQDEEDFCMEALIMGKFNHQNVVRCIGICFQKQPY-MIVLEYMEGGDMKSFLRECRPH

LTVADTSEE--DIILNVRKQLLSICLQVGNGMCYLASQRFIHRDLAARNCMIDDDG---IIKVADFGLSEDI-YSQNYFRQLEGSKDSSSSPVKLPLKWM
       .|     . . | || .|. |  |  || ...||||| |||||     |   . |.|||| . || |   |.|   | .        .| |||
-------PESLQPSQLTMKDLLQCCCDVAQGCHYLEENHFIHRDIAARNCLLTCKGPGRVAKIADFGMARDITYRADYYRK--GGR------AMMPVKWM

ALESIHDGLFSEKSDVWSYGVLCWEVFSLGRVPYPGLDPVGVVELLNTGGRLYTPNNEACSKEIYSLMTSCWSESPDDRPVFSDLVSSINT
  |   ||.|  |.||||.||||||.||||..||||     | |.. .|||.  | |  |   .| .|| ||   | ||| | ... .|  
PPEAFMDGIFTSKTDVWSFGVLCWEIFSLGYMPYPGRHNQEVMEFVTEGGRMDPPRN--CPQPVYRIMTQCWQHQPEDRPKFVTILEHIQY

Kinase AqueK382.AA InsR 409-691 34 8e-68 226.86 In-house 1-278 (278) Show / Hide
Range on Protein: 409-691
Range on HMM: 1-278/278
Sequence Identity: 34% (100 aa)

ISVQETVGQGEFGIVYRG----VMTIENQMPQPVAVKTLKGFYSKSDIDSLLDECIIMMSFDNLNVLPLIGVCLDLGPAPYIIMPFMSRGSLLSYLKKER
|      ||| || || |    ..  |     ..|.||..   |  .    | |  .|  |.  .|  | |||    |. |..| .| .| | |||   |
IVLIRECGQGSFGMVYEGIAKGIVPDEEWRFGRCAIKTVNENASMRERIEFLNEASVMKEFNCHHVVRLLGVCSRGQPM-YVVMEMMTYGDLKSYLRSRR

PNLTVADTSEEDII----LNVRKQLLSICLQVGNGMCYLASQRFIHRDLAARNCMIDDDGIIKVADFGLSEDIYSQNYFRQLEGSKDSSSSPVKLPLKWM
|        . ...       . |...   ..  || |||.  |.|||||.||||...|. .|..|||.  |||   | |   ..        .||  ||
PEEEF---NNPGCNRNQHVPCLDQMHQMAAEICDGMAYLAAKKFVHRDLACRNCMVNHDFTVKIGDFGMTRDIYEHDYYRKGGKG--------MLPVRWM

ALESIHDGLFSEKSDVWSYGVLCWEVFSLGRVPYPGLDPVGVVELL-NTGGRLYTPNNEACSKEIYSLMTSCWSESPDDRPVFSDLVSSINT
| ||. || |. .|||||.||. ||. .||  || ||    | .     |. |  |  | |..  . ||  ||  .| .|| | |.....  
APESLKDGVFTTHSDVWSFGVVLWEMVTLGEQPYQGLSNEQVLKYIGMDGNVLRPP--ENCPEYWQELMMMCWQYQPKMRPTFLDIIHYLCD

Kinase AqueK382.AA S_TKc 409-693 19 1.1e-33 119.09 SMART 1-231 (231) Show / Hide
Range on Protein: 409-693
Range on HMM: 1-231/231
Sequence Identity: 19% (58 aa)

ISVQETVGQGEFGIVYRGVMTIENQMPQPVAVKTLKGFYSKSDIDSLLDECIIMMSFDNLNVLPLIGVCLDLGPAPYIIMPFMSR--GSLLSYLKKERPN
  . ...|.| || ||... .      . ||.| .|        .... |  |... .  |.  |..|. |     |..| ...   |.|..|.|| ...
YEILRKIGKGAFGKVYKCRHKK---TGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIKKRGRH

-----LTVADTSEEDIILNVRKQLLSICLQVGNGMCYLASQRFIHRDLAARNCMIDDDGIIKVADFGLSEDIYSQNYFRQLEGSKDSSSSPVKLPLKWMA
     ..  ..              ... |. ... |. |...|||||   | ..|.   ||..||||.  .                 . .   . .||
GLRFPFPE-HAR-------------FYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----------------TTFCGTPWYMA

LESIHDGLFSE-KSDVWSYGVLCWEVFSLGRVPYPGLDPVGVVELLNTGGRLYTPNNEACSKEIYSLMTSCWSESPDDRPVFSDLVSSI-----NTLI
 | .    ..  |.|.|| |.. .| .. |. |.|      . ....  |          |.|  ...  |.   |..||   ..  .         .
PEVL---GYGKCKCDWWSCGCILYEMLC-GYPPFP-----QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase AqueK382.AA Pkinase 409-689 21 2.8e-29 104.59 Pfam 1-293 (293) Show / Hide
Range on Protein: 409-689
Range on HMM: 1-293/293
Sequence Identity: 21% (68 aa)

ISVQETVGQGEFGIVYRGVMTIENQMPQPVAVKTLKGFYSKSDID--SLL-DECIIMMSFDNLNVLPLIGVCLDLGPAPYIIMPFMSRG----SLLSYLK
. . ...|.| || ||...   ...    ||||..|    ||. |   ..  |. || ...  |.. |.... | .. .|..|...  |    .| .|..
YHIGRKIGSGSFGCVYKCHHKGTGK---IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED-KDHIYMVMEYCEGGLYVMDLFDYIS

KERPNLTVADTSEEDIIL--NVRKQLLSICLQVGNGMCYLASQRFIHRDLAARNCMIDDDGII----KVADFGLSEDIYSQNYFRQLEGSKDSSSSPVKL
            ...  .     ... ....|.  |. |. |...|||||   |..||..| |    |..||||.. ..           ..|  . .  
T-----------WRHGCFYFS-EWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD---------Y-NNS-MTTFCG

PLKWMALESIH-DGLFSEKSDVWSYGVLCWEVFSLGRVPYPGL----DPVGVVELLNTGGR--LYTPNNEACS-------------------KEIYSLMT
 . .|| | |  .   . |.|.||.|....|... || |.||     . .   ....  ..  |  .  . ||                   .|  ....
TPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLC-GRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIK

SCWSESPDDRPVFSDLVSS--I
.|.   | .|| . ... .  .
WCLCKDPKKRPTAEQILQHPWF