Gene AqueK395 (A.queenslandica)

AqueK395

Species: A.queenslandica
Alias: AqueK395
External Links:
Annotation:

Classification

Group: TK
Family: REF

Sequence

Name Sequence Type Origin Length Description Download
AqueK395.AA Protein None 917 None Fasta, JSON
AqueK395.kin_dom Protein Kinase Domain None 293 None Fasta, JSON

Protein domain

Protein domains of AqueK395.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Pkinase_Tyr AqueK395.AA Pkinase_Tyr 499-791 41 8.3e-132 447.03 Pfam 1-270 (270) Show / Hide 
Range on Protein: 499-791
Range on HMM: 1-270/270
Sequence Identity: 41% (124 aa)

IQFDHLLGEGCFGEVYLGRLKQEFSSSVLTAYFRQNNTNGFVAIKLLKPTASSSE--KNDFLKEIELMKKISVGKNPRVVNMLGSVT-VQEP--MLLVTE
|.|.. ||||.|||||.|..|             . ||.  ||.| ||..|....  . ||..|...||..  |..| .|...| .|  .||  ...|.|
ITFGKKLGEGAFGEVYKGTWKG-----------DPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQL--GHHPNIVRLYGVCTDQGEPNQIYIVME

FVVHGDLLTFLRACRKKIVFHRGKGQHNEDTSDEQFGVLDSNDLVSFAYQITSGMEYLASLQVVHRDLACRNILVGEGKSLKITDFGMSRMIYHDTAY-V
.. |||||..||. |                  |. . |.  ||.....|| .|||||.| . .|||||.||.||.|..  ||.|||..| ||.|  | .
YMPHGDLLDYLRKHR------------------EDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYR

KTTKGKLPLKWMSIESIIDRIFTTASDVWSFGICLWEIATLGNVP-YPTVSNEDLLPML-NQGYRMEKPNSCSDEIYQIMLSCWEALPDERPLFSDLRSN
|...|||| |||. |.| ...|||.|||||||...||| |.|  | || .|||... ..  .||||..|  |.||||..|..||.. |..|| ||.... 
KRGGGKLPIKWMAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQ

F
.
L
TyrKc AqueK395.AA TyrKc 499-791 39 1e-128 434.85 SMART 1-280 (280) Show / Hide 
Range on Protein: 499-791
Range on HMM: 1-280/280
Sequence Identity: 39% (127 aa)

IQFDHLLGEGCFGEVYLGRLKQEFSSSVLTAYFRQNNTNGFVAIKLLKPTASSSEKNDFLKEIELMKKISVG-KNPRVVNMLGSVTVQ-------EPMLL
|.... ||||.|||||.|..|                    ||.| ||. |    . ||..|...|.|.  | ..| .|...| .| |       ||...
ITLGKKLGEGAFGEVYKGTWK------------------IQVAVKMLKEDA----REDFMREARIMCKL--GGHHPNIVRLYGVCTQQGRNFMYIEPLMI

VTEFVVHGDLLTFLRACRKKIVFHRGKGQHNEDTSDEQFGVLDSNDLVSFAYQITSGMEYLASLQVVHRDLACRNILVGEGKSLKITDFGMSRMIYHD--
|.|.. ||||. .||..|.|                     |   ||.||..|| .|||||.| ...|||||.||.||||..  ||.|||.|| ||.|  
VMEYMPHGDLKDYLRKHRPK---------------------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQ

-----TAYVKTT--KGK--LPLKWMSIESIIDRIFTTASDVWSFGICLWEIATLGNVPYPT-----VSNEDLLPMLNQGYRMEKPNS--------CSDEI
       |.|..   ||  ||..||..|.| ...|||.|||||||.|.||| |.|  |||      .||....  . |||||..| .        |.||.
QGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEM

YQIMLSCWEALPDERPLFSDLRSNF
||||..||.. |..|| ||.... |
YQIMKQCWHEDPEDRPTFSEIHECF
Kinase AqueK395.AA TK 499-791 25 3.6e-114 384.3 In-house 1-486 (486) Show / Hide 
Range on Protein: 499-791
Range on HMM: 1-486/486
Sequence Identity: 25% (122 aa)

IQFDHLLGEGCFG---EVYLGRLKQEFSSSVL--------TAYFRQ--NNTNGFVAIKLLKPTASSSEKN-------------DFLKEIELMKKIS--VG
|.. . |||| ||   |||.|.....  .           | ....  ....  ||.| ||.....|..              |||.| | ||. .  .|
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

KNPRVVNMLG----SVTV--------QEPMLLVTEFVVHGD----LLTFLRACRKKIVFHRGKGQHNEDTS-----------------------------
. | .|...|    ....        |||...|.|.. |||    |...||.||.|   .  ........                              
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-----DEQFGVLDSNDLVS-------------------FAYQITSGMEYLASL------QVVHRDLACRNILVGEGKS-----------LKITDFGMS--
     ....  |.  ||..                   ...|| .|||||.|.      ..||||||.||.||||..             ||.|||.|  
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQ

------RMIYHDTAYVKTT------------------------KGKLPLKWMSIESIIDRI---------FTTASDVWSFGICLWEIATLGNVPYPT-VS
      | ||.|. |....                        .||||..||. |.. ||.         |||.|||||||...||| |.| .||.  .|
GSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMS

N---------EDLLPMLNQG--------------YRMEKPNSCS--------------DEIYQIMLSCWEALPDERPLFSDLRSNF
|         .... .| .|              .||..|  |.              .|.|..|..||.. |..|| ||.|.. .
NQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase AqueK395.AA KIN6 499-791 36 2.2e-101 335.81 In-house 1-305 (305) Show / Hide 
Range on Protein: 499-791
Range on HMM: 1-305/305
Sequence Identity: 36% (115 aa)

IQFDHLLGEGCFGEVYLGRLKQEFSSSVLTAYFRQ-------NNTNGFVAIKLLKPTASSSEKNDFLKEIELMKKISVGKNPRVVNMLGSVTVQEPMLLV
|. ||.||.| |. ||.| .| .  | ..  . |        ....  .|.| |   |   .. ||..||..||.   | .|..||||| ||. .. .||
IHKDHKLGHGAFCNVYKGKIKGK--SPIMQWINRVNMRIEMMRYQDCQCAVKMLPSHADEMAHHDFMHEIAFMKQL--GHHPHLVNMLGCVTNSYKPCLV

TEFVVHGDLLTFLRACRKKIV--------FHRGKGQHNEDTSDEQFGVLDSNDLVSFAYQITSGMEYLASLQVVHRDLACRNILVGEGK---SLKITDFG
 |.  |.||| .||  .. ..        .|   .. . . .|    ..   ||..||.||. |||||.|   .||||| ||.|| ||    . || |||
VEYCCHMDLLKYLRNRCQYMMNLDDLGINYH---CPDENSRYDDMM-CIRHKDLYMFAWQICDGMEYLHSKNCIHRDLAARNVLVTEGCRMKTCKISDFG

MSRMIYHDTAYVKTTKGK-LPLKWMSIESIIDRIFTTASDVWSFGICLWEIATLGNVPYPTVS-NEDLLPMLNQGYRMEKPNSCSDEIYQIMLSCWEALP
. | .| | .  ..  |. ||.|||. |...   | . |||||||. ..|. .|| ||||..   ..... .  | |...|  |..||| || ||| ..|
LCRYPYMDQFQYTSKGGRYLPIKWMAPECLKHYEFSYKSDVWSFGVLMFEMFSLGDVPYPEMQRPTEMIEHHRSGRRPKHPKWCPEEIYDIMQSCWQEKP

DERPLFSDLRSNF
|.|| |...|  |
DDRPEFNEMRMQF
Kinase AqueK395.AA TK-Unique 499-791 36 5e-100 338.63 In-house 1-294 (294) Show / Hide 
Range on Protein: 499-791
Range on HMM: 1-294/294
Sequence Identity: 36% (114 aa)

IQFDHLLGEGCFGEVYLGRLKQEFSSSVLTAYFRQNNTNGFVAIKLLKPTASSSEKNDFLKEIELMKKISVGKNPRVVNMLGSVT-VQEPMLLVTEFVVH
. .. ..||| ||.|. | ...             ..    ||.|.||  |.  .| ||||||..||.  .|. | .|..||  |  .||.... |..  
LEVGDVIGEGAFGQVWRGEVWGIW---------KHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKE--LGDHPNIVQCLGCCTKSDEPWMIIMEYCPC

GDLLTFLRACRKK-----------IVFHRGKGQHNEDTSDEQFGVLDSNDLVSFAYQITSGMEYLAS--LQVVHRDLACRNILVGEGKSLKITDFGMSRM
|.|...|| ||..           . ||. . . ...        ... ||..||.|| .|||||||   ..|||||. ||.|..|.| .||.||||.| 
GNLQHYLRTCRPAMRQHQTYGNLKFDFHHMPDKPRTE-------PISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARD

IYHDTAYVKT-TKGKLPLKWMSIESII--DRIF-TTASDVWSFGICLWEIATLGNVPYPTVSNEDLLPMLNQGYRMEKPNSC-SDEIYQIMLSCWEALPD
.|....|... ..|..|..||. ||.   .... || |||||||. .|||.|||  ||| ....|.. .. .||||..|..| |.|.|..| |||   |.
VYTNGVYSMMCSQGRIPIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYRMPQPEHCCSHEMYNLMKSCWQWEPE

ERPLFSDLRSNF
||| |..... .
ERPSFRQIKHRL
Kinase AqueK395.AA UTK 499-791 31 4.7e-96 325.41 In-house 1-296 (296) Show / Hide 
Range on Protein: 499-791
Range on HMM: 1-296/296
Sequence Identity: 31% (103 aa)

IQFDHLLGEGCFGEVYLGRLKQEFSSSVLTAYFRQNNTNGFVAIKLLKPTAS-SSEKN---DFLKEIE---LMKKISVGKNPRVVNMLGSVTVQEPMLLV
.|.  .||.| ||||...|..|.   . . .          ||.| ....|.   |.    ||..|     .||. .    | |....| .| .||...|
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMD----------VAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFH--WHPNVLRLVGVCTQEEPWMIV

TEFVVHGDLLTFLRACRKKIVFHRGKGQHNEDTSDEQFGVLDSNDLVSFAYQITSGMEYLASLQVVHRDLACRNILVGEG-------KSLKITDFG---M
||. . |||...|| .|..                ..   |.. .....|..| .||.||.| ..||||||.||.||..         . || |||   |
TEYMENGDLRSYLRRHRPTPP--------------ACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGM

SRMIYH--------DTAYVKTT-KGKLPLKWMSIESIIDR-IFTTASDVWSFGICLWEIATLGNVPYPTVSNEDLLPMLNQG--YRMEKPNSCSDEIYQI
||...         .. |.. .  ...|..||. |.....  |||.|||||||. .||| | |..|||  ||....  .  |  |||..| .|....|..
SRRVNTFHFSNRYWESYYYMAQHQDRWPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRL

MLSCWEALPDERPLFSDLRSNF
|..||.. |.||| | ||.. .
MHRCWHYDPQERPDFEDLVQQM
Kinase AqueK395.AA FGFR 499-791 39 2.8e-91 309.58 In-house 1-293 (293) Show / Hide 
Range on Protein: 499-791
Range on HMM: 1-293/293
Sequence Identity: 39% (120 aa)

IQFDHLLGEGCFGEVYLGRLKQEFSSSVLTAYFRQN--NTNGFVAIKLLKPTASSSEKNDFLKEIELMKKISVGKNPRVVNMLGSVTVQEPMLLVTEFVV
    . |||||||.| ..  |             ..  . .  ||.| ||  ..  .  |   |.| || |  ||.. ..| ||  | . |   . |.  
LTLGKMLGEGCFGQVWMAEAKG----------IDCDRPEKEITVAVKMLKMNHTDKDLSDLVSEMEMMKMI--GKHKNIINLLGCCTQEGPLYVIVEYCH

HGDLLTFLRACRKKIVFHRGKGQ----HNEDTSDEQ-----FGVLDSNDLVSFAYQITSGMEYLASLQVVHRDLACRNILVGEGKSLKITDFGMSRMIYH
|| |  |||| | .    .  .|        .. .|        | . ||||.|||.  |||||||  ..||||| ||.||...  .|| ||| .| | .
HGNLRDFLRARRPPGMDYKKDSQEYTDYKPRKPEQQDDIELIPNLTQKDLVSCAYQVARGMEYLASRKCIHRDLAARNVLVTDDYVMKICDFGLARDIHC

DTAYVKTTKGKLPLKWMSIESIIDRIFTTASDVWSFGICLWEIATLGNVPYPTVS-NEDLLPMLNQGYRMEKPNSCSDEIYQIMLSCWEALPDERPLFSD
   | ||| | || |||  |.  ||..|. |||||.|. |||| |.|  |||..   |.|   |  |.|||||  || ||| .| .|| . |..|| |  
IDYYRKTTNGRLPIKWMAPEALFDRVYTHQSDVWSYGVLLWEIMTYGGQPYPHIPSVEELYKYLKEGHRMEKPHNCSQEIYHMMCQCWHFKPCQRPTFKQ

LRSNF
|   .
LVEYL
Kinase AqueK395.AA Ret 540-793 41 2.8e-91 309.58 In-house 32-293 (293) Show / Hide 
Range on Protein: 540-793
Range on HMM: 32-293/293
Sequence Identity: 41% (112 aa)

VAIKLLKPT-ASSSEKNDFLKEIELMKKISVGKNPRVVNMLGSVTVQE--PMLLVTEFVVHGDLLTFLRACRKK-IVFHRGKGQHN---EDTSD-EQFGV
||.| ||   |.|||  | | | .| |...    | |.  .|  . ..  | .|. |.   | |  |||  ||.   .  . |  |    | .| .   |
VAVKMLKRNTANSSEYHDLLSEFQLLKQVN---HPHVIKLYGACIQDDPFPTCLIVEYCKYGCLREFLRLSRKIGPYYEYSIGNRNCSIVDHPDGKD--V

LD-----SNDLVSFAYQITSGMEYLASLQVVHRDLACRNILVGEGKSLKITDFGMSRMIYHDTAYVKTTKGKLPLKWMSIESIIDRIFTTASDVWSFGIC
.        ...||| ||  || ||... .|||||| ||.|| ||. .|| ||| .| .| | .|||  |...| ||| |||  | ..|| |||||||. 
INRFDIGMKMIISFAWQICKGMHYLSEMKLVHRDLAARNVLVAEGRICKISDFGLTRDVYEDDSYVKRSKDRIPVKWMAIESLYDHVYTTKSDVWSFGVL

LWEIATLGNVPYPTVSNEDLLPMLNQGYRMEKPNSCSDEIYQIMLSCWEALPDERPLFSDLRSNFDR
.||| |.|  ||| .  | |   |  ||||. |  || |.| ||. ||   || || | .. ..| .
CWEIVTMGANPYPGIPPERLWQLLKTGYRMDRPENCSEEMYRIMRQCWKQEPDKRPVFKFISKDFEK
Kinase AqueK395.AA VEGFR 632-791 50 6.5e-87 295.05 In-house 170-332 (332) Show / Hide 
Range on Protein: 632-791
Range on HMM: 170-332/332
Sequence Identity: 50% (82 aa)

LDSNDLVSFAYQITSGMEYLASLQVVHRDLACRNILVGEGKSLKITDFGMSRM-IYHDTAYVKTTK-GKLPLKWMSIESIIDRIFTTASDVWSFGICLWE
|.. ||.....|.  |||.|||  ..||||| ||||. | . .|| ||| .|  || |  ||. .. |.||.|||..||| |...|| |||||.|. |||
LTMEDLICYSFQVARGMEFLASRKCIHRDLAARNILLCENNVVKICDFGLARHGIYKDPDYVRKGDQGRLPIKWMAPESIFDKVYTTYSDVWSYGVFLWE

IATLGNVPYPTVS-NEDLLPMLNQGYRMEKPNSCSDEIYQIMLSCWEALPDERPLFSDLRSNF
| .|| .|||.|. .|.. . |. ||||..|  |  |||.|||.||   | |||.||.|   .
IFSLGGSPYPGVQIDEEFCNRLKDGYRMRAPDYCTPEIYHIMLDCWHKEPEERPHFSELVEHL
Kinase AqueK395.AA Src 540-791 38 2.1e-83 283.21 In-house 26-255 (255) Show / Hide 
Range on Protein: 540-791
Range on HMM: 26-255/255
Sequence Identity: 38% (98 aa)

VAIKLLKPTASSSEKNDFLKEIELMKKISVGKNPRVVNMLGSVTVQEPMLLVTEFVVHGDLLTFLRACRKKIVFHRGKGQHNEDTSDEQFGVLDSNDLVS
||.| |||     . ..||.|...|||    . ...|...  ..  || . |||.  || ||..|..                   |.. . |  ..|..
VAVKTLKPGT--MSPEAFLQEAQIMKKL---RHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKK-------------------DGEGRHLHLPQLID

FAYQITSGMEYLASLQVVHRDLACRNILVGEGKSLKITDFGMSRMIY-HDTAYVKTTKGKLPLKWMSIESIIDRIFTTASDVWSFGICLWEIATLGNVPY
.| |. .||.|| | ...||||| ||.||||.   |. |||  |.|   |  |.  .  |.| ||.  | |  . ||. |||||||| |.|| | | |||
MAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLARLIKEDDDEYCARHGAKFPIKWTAPEAINYGRFTIKSDVWSFGILLTEIVTYGRVPY

PTVSNEDLLPMLNQGYRMEKPNSCSDEIYQ-IMLSCWEALPDERPLFSDLRSNF
|  .|.. | .. .|||| .|  | ||.|. ||| ||.. |..|| |  |.. .
PGMTNHEVLQQVERGYRMPCPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL
Kinase AqueK395.AA InsR 499-793 36 1.2e-80 270.63 In-house 1-278 (278) Show / Hide 
Range on Protein: 499-793
Range on HMM: 1-278/278
Sequence Identity: 36% (108 aa)

IQFDHLLGEGCFGEVYLGRLKQEFSSSVLTAYFRQNNTNGFVAIKLLKPTASSSEKNDFLKEIELMKKISVGKNPRVVNMLGSVTVQEPMLLVTEFVVHG
|     .|.| || ||.| .|   .  . .         | .||| ..  ||. |. .||.| . ||..   .   ||. || ..  .||. | |.  .|
IVLIRECGQGSFGMVYEGIAKGIVPDEEWRF--------GRCAIKTVNENASMRERIEFLNEASVMKEF---NCHHVVRLLGVCSRGQPMYVVMEMMTYG

DLLTFLRACRKKIVFHRGKGQHNEDTSDEQFGVLDSNDLVSFAYQITSGMEYLASLQVVHRDLACRNILVGEGKSLKITDFGMSRMIYHDTAYVKTTKGK
|| ..||. |   .|       |.    . . |    .... | .| .|| |||..  ||||||||| .| .    || |||| | ||    | | .||.
DLKSYLRSRRPEEEF-------NNPGCNRNQHVPCLDQMHQMAAEICDGMAYLAAKKFVHRDLACRNCMVNHDFTVKIGDFGMTRDIYEHDYYRKGGKGM

LPLKWMSIESIIDRIFTTASDVWSFGICLWEIATLGNVPYPTVSNEDLLPML-NQGYRMEKPNSCSDEIYQIMLSCWEALPDERPLFSDLRSNFDR
||  ||. ||. | .|||.|||||||. |||..|||  ||   |||  |      |  ...|  |..  ...|  ||   |  ||.| |. ..   
LPVRWMAPESLKDGVFTTHSDVWSFGVVLWEMVTLGEQPYQGLSNEQVLKYIGMDGNVLRPPENCPEYWQELMMMCWQYQPKMRPTFLDIIHYLCD
Kinase AqueK395.AA RTKB 499-791 36 2.7e-78 263.53 In-house 1-264 (264) Show / Hide 
Range on Protein: 499-791
Range on HMM: 1-264/264
Sequence Identity: 36% (108 aa)

IQFDHLLGEGCFGEVYLGRLKQEFSSSVLTAYFRQNNTNGFVAIKLLKPTASSSEKNDFLKEIELMKKISVGKNPRVVNMLGSVTVQEPMLLVTEFVVHG
.. .. ||.| ||||... ..            |  ||   .| | ||| ||. |. ||..|. .|| .  |  | |. ..|     || .|  |.  .|
VWLGEKLGNGAFGEVFQAWVRN-----------RHMNTEQSCAAKVLKPGASYEERQDFCSEMTVMKEL--GWHPNVIGIIGHCLQDEPYILLVELCELG

DLLTFLRACRKKIVFHRGKGQHNEDTSDEQFGVLDSNDLVSFAYQITSGMEYLASLQVVHRDLACRNILVGEGKSLKITDFGMSRMIYHDTAYVKTTKGK
 |  .||.||               .|... . | .  ||.|. || .|| .| . .|.||||. ||.||. . . || ||||.| | |.   ..||  .
NLRDYLRMCR---------------ASQHNPQSLKQAQLVDFCHQIACGMAFLHQHNVIHRDLCARNVLVDQQLHCKICDFGMAREIDHEC--YETTCTR

LPLKWMSIESIIDRIFTTAS-DVWSFGICLWEIATLGNVPYPTVSNEDLLPMLNQGYRMEKPNSCSDEIYQIMLSCWEALPDERPLFSDLRSNF
|| ||| .||. .||.|| | ||||||.  ||| .|| .||.. .| |... |  |.|..|| . . ... ||  || . ...|| |. | . |
LPIKWMAPESWAHRIYTTKSGDVWSFGVTMWEIFSLGGTPYQQYRNGDIFYWLESGHRLPKPRQMPQAADHIMQMCWQMEAQHRPDFDELVDAF
Kinase AqueK395.AA S_TKc 499-795 20 8.1e-42 146.16 SMART 1-231 (231) Show / Hide 
Range on Protein: 499-795
Range on HMM: 1-231/231
Sequence Identity: 20% (64 aa)

IQFDHLLGEGCFGEVYLGRLKQEFSSSVLTAYFRQNNTNGFVAIKLLKPTASSSEKNDFLKEIELMKKISVGKNPRVVNMLGSVTVQEPMLLVTEFVVH-
 ..  ..|.| ||.||..| |                |.  |||| .|        .....||...||    . | .|.....    . . .|.|.. . 
YEILRKIGKGAFGKVYKCRHKK---------------TGRIVAIKIIK--------EHIRREIQILKK----HHPNIVKLYDVFQD-DHLYMVMEYCDGD

-GDLLTFLRACRK----KIVFHRGKGQHNEDTSDEQFGVLDSNDLVSFAYQITSGMEYLASLQVVHRDLACRNILVGEGKSLKITDFGMSRMIYHDTAYV
 |||..... ...    .                    ...  .  ...||| ...||. |....||||   |||. |   .||.|||..| .       
LGDLFDYIKKRGRHGLRF--------------------PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------

KTTKGKLPLKWMSIESIIDRIFTT-ASDVWSFGICLWEIATLGNVPYPTVSNEDLLPMLNQGYRMEKPNSCSDEIYQIMLSCWEALPDERPLFSDLRSNF
  |     . .|. | .    ... ..|.||.|..|.| .. |  |.|     ..  |...          |.|  ...  |..  |..||   ..  . 
--TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLC-GYPPFP-----QMQMMFKKIG--------SPEAKDFIRKCLQKDPEKRPTA-EALQDE

-----DRIL
     .  .
WDIKCHPWF
Kinase AqueK395.AA Pkinase 499-791 19 3.1e-30 108.01 Pfam 1-293 (293) Show / Hide 
Range on Protein: 499-791
Range on HMM: 1-293/293
Sequence Identity: 19% (65 aa)

IQFDHLLGEGCFGEVYLGRLKQEFSSSVLTAYFRQNNTNGFVAIKLLKPTASSSEKN--DFL-KEIELMKKISVGKNPRVVNMLGSVTVQEPMLLVTEFV
...   .|.| ||.||... | .                  ||.| .|    .|.|.  ...  ||..||...  .|  .| ......    . .|.|..
YHIGRKIGSGSFGCVYKCHHKGTGK---------------IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLN-HPN--IVRLYDWFEDKDHIYMVMEYC

VHG----DLLTFLRACRKKIVFHRGKGQHNEDTSDEQFGVL--DSNDLVSFAYQITSGMEYLASLQVVHRDLACRNILVGEGKSL----KITDFGMSRMI
 .|    || .....                    .. |..  . ... ...||| .|.||. |  ..||||   |||. .   .    ||.||| .. .
EGGLYVMDLFDYIST--------------------WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQF

YHDTAYVKTTKGKLPLKWMSIESII-DRIFTTASDVWSFGICLWEIATLGNVPYPTV----SNEDLLPMLNQGYRMEKPNSCS-----------------
.    .. .|     . .|. | |  ..  ....|.||.|. |.| .. |. |.|      .  | . |...  . . . ...                 
D-Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLC-GRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHW

------DEIYQIMLSCWEALPDERPLFSDLRSN--F
      .|  ... .|..  | .|| . ..     |
TFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase AqueK395.AA VEGFR 532-622 30 9.5e-12 40.76 In-house 24-115 (332) Show / Hide 
Range on Protein: 532-622
Range on HMM: 24-115/332
Sequence Identity: 30% (29 aa)

RQNNTNGFVAIKLLKPTASSSEKNDFLKEIELMKKISVGKNPRVVNMLGSVTV---QEPMLLVTEFVVHGDLLTFLRACRKKIVFHRGKGQHNE
|   |.  || | ||..| .||.   . |..... |  |.   |||.|| .|    . |..   |.. .| |...||. |.  |    |. | .
RKMETCTTVAVKMLKEGATASEHRALMSELKMLIHI--GHHLNVVNFLGCCTKNIQKGPLMVIVEYCCFGNLSNYLRTKRMYFVPYPDKSPHMR
Kinase AqueK395.AA Src 499-516 50 3e-05 13.75 In-house 1-18 (255) Show / Hide 
Range on Protein: 499-516
Range on HMM: 1-18/255
Sequence Identity: 50% (9 aa)

IQFDHLLGEGCFGEVYLG
|..   ||.|.||||. |
IKLCRKLGQGQFGEVWMG
Kinase AqueK395.AA Ret 499-513 60 0.004865 6.17 In-house 1-15 (293) Show / Hide 
Range on Protein: 499-513
Range on HMM: 1-15/293
Sequence Identity: 60% (9 aa)

IQFDHLLGEGCFGEV
 |.|  |||| || |
LQLDDTLGEGHFGQV