Gene AqueK424 (A.queenslandica)

AqueK424

Species: A.queenslandica
Alias: AqueK424
External Links:
Annotation:

Classification

Group: TK
Family: Src
Subfamily: Src-Aque1

Sequence

Name Sequence Type Origin Length Description Download
AqueK424.AA Protein None 630 None Fasta, JSON
AqueK424.kin_dom Protein Kinase Domain None 248 None Fasta, JSON

Protein domain

Protein domains of AqueK424.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
SH3 AqueK424.AA SH3 191-249 35 1.8e-15 58.62 SMART 1-58 (58) Show / Hide 
Range on Protein: 191-249
Range on HMM: 1-58/58
Sequence Identity: 35% (21 aa)

KLFMASYNFEGLRPHDLTLKKGEVLEVVKYDDDDEWWYMYSLRTDKEGYVPINYILPIE
. . | |....  | .|..|||....|.. | ||.||.    || .||..| ||. .|.
PYVRALYDYQAQNPDELSFKKGDIITVLEKD-DDGWWKGRCNRTGQEGWFPSNYVEEID
SH3_1 AqueK424.AA SH3_1 194-242 32 9.3e-11 39.35 Pfam 1-49 (49) Show / Hide 
Range on Protein: 194-242
Range on HMM: 1-49/49
Sequence Identity: 32% (16 aa)

MASYNFEGLRPHDLTLKKGEVLEVVKYDDDDEWWYMYSLRTDKEGYVPI
 | | ...  | .|..|||....|.. .||..||   ...| .||..| 
VALYDYQAQQPDELSFKKGDIIHVIEKSDDWDWWKGRCNNTGQEGWFPS
SH3_2 AqueK424.AA SH3_2 192-248 17 8.2e-08 30.25 Pfam 1-68 (68) Show / Hide 
Range on Protein: 192-248
Range on HMM: 1-68/68
Sequence Identity: 17% (12 aa)

LFMASYNFEG-LRPHD-----LTLKKGEVLEVV--KYDDDDEWWYM-YSLRTDKE--GYVPINYILPI
.. .  ....  .. .     |..|||.|..|   .  |.|.||.  ... . ..  |..|.... ..
YYRVHCDYVPATYCNENHEPQLHFKKGDVIKVIDNGDKDWDNWWWCWETIWGGRRMRGWFPSQWVEEC
SH2 AqueK424.AA SH2 259-345 36 2.2e-24 88.28 SMART 1-87 (87) Show / Hide 
Range on Protein: 259-345
Range on HMM: 1-87/87
Sequence Identity: 36% (33 aa)

YIYYH-TVSRDEAEERLSQADTQAGTFLIRHSESNPRQHYSLSLNDGAAITHYRIYMYIQKNKYYMNP--RVQFDSLNDLVHYYMMKADG
. .||  .||.|||. | .   . |.||.| |||  ...|.||. ..  . ||||      .|||     |..|.|| .||..|.  ..|
QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSES-NPGDYVLSVRWKGKVKHYRIRRNDD-GKYYIDETWRRKFPSL-ELVNHYQHNPLG
SH2 AqueK424.AA SH2 261-339 40 1.8e-22 67.8 Pfam 1-81 (81) Show / Hide 
Range on Protein: 261-339
Range on HMM: 1-81/81
Sequence Identity: 40% (34 aa)

YYH-TVSRDEAEERLSQADTQAGTFLIRHSESNPRQHYSLSLNDGA---AITHYRIYMYIQKNKYYMNPRVQFDSLNDLVHYY
.||  .|| |||..| .   . ||||.| |||.| . |.||. |.     ..||||    .. .||.  |..|.||..||..|
WYHGKISRQEAERLLMNPGNPDGTFLVRESESTPGD-YTLSVRDDGPGDRVKHYRIQRTDNG-GYYITGRHKFCSLQELVEHY
Kinase AqueK424.AA Src 375-622 41 1e-93 317.63 In-house 1-255 (255) Show / Hide 
Range on Protein: 375-622
Range on HMM: 1-255/255
Sequence Identity: 41% (105 aa)

IKFEQCINAGRFGETWKGNCKGKGPVMIKTNIATDITQETFIEEAKILVKFYHKNIISLYGVCIEDYPFYIVTEPM-NGNLKDYLT---TKYLVTSAELV
||... . .| ||| |.|  .|. .| .||  . .  .| | .||.|. |. |.....|| || .. |.||||| | .|.| |||    .   .   .|.
IKLCRKLGQGQFGEVWMGYWNGNTKVAVKTLKPGTMSPEAFLQEAQIMKKLRHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKKDGEGRHLHLPQLI

DIAIQVTKGMMYLGEQGYIHCDLRAENILLRDHNTVKIANFHLAQHLN--GSKYSTVEGTKLAIRWTAPEAYTLNQLSIKSDVWSFGILLWELVTKGKEP
|.| || .||.||... ||| ||.| |.|  ..| .|.| | ||. .      |.  .| |. |.|||||| . .. .||||||||||||.|.||.|. |
DMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLARLIKEDDDEYCARHGAKFPIKWTAPEAINYGRFTIKSDVWSFGILLTEIVTYGRVP

YSGMTDEDVKEAVSKGYHMLLPQGCPEPFKQ-LMLNCWKQNKDKRPSFKNIFDLL
| ||| ..| ..|..||.|  |..||. . . .|| ||..  ..|| |. ... |
YPGMTNHEVLQQVERGYRMPCPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL
Kinase AqueK424.AA SFK-Src 375-617 41 7.3e-91 269.46 In-house 1-250 (259) Show / Hide 
Range on Protein: 375-617
Range on HMM: 1-250/259
Sequence Identity: 41% (104 aa)

IKFEQCINAGRFGETWKGNCKGKGPVMIKTNIATDITQETFIEEAKILVKFYHKNIISLYGVCIEDYPFYIVTEPM-NGNLKDYLTT--KYLVTSAELVD
|. |.   .| ||. |||   ..  | .||     . .| | .|| .. |  | | | || ||    | ||.|| | .| | |||        .   |||
IRLEKKLGSGQFGDVWKGRWNNTTEVAVKTLKPGAMSAEEFLQEAQVMKKLRHPNLIQLYAVCTDGEPIYIITELMKYGSLLDYLHEPHGRSLRMPQLVD

IAIQVTKGMMYLGEQGYIHCDLRAENILLRDHNTVKIANFHLAQHL-NGSK-YSTVEGTKLAIRWTAPEAYTLNQLSIKSDVWSFGILLWELVTKGKEPY
 | ||  || || .| ..| || | |.|  | |..|.. | ..  | . .  |   || |  |.|||||| . |. ||||||||||||. |.|| |  ||
MAAQVAHGMAYLEAQNFVHRDLAARNVLVGDNNVCKVGDFGMSRVLAQDDEGYTAHEGAKFPIKWTAPEAMNMNRFSIKSDVWSFGILMMEIVTYGRIPY

SGMTDEDVKEAVSK--GYHMLLPQGCPEPFKQLMLNCWKQNKDKRPSFKN
 |||   |   | .  || |  |..||. . ..|..||... | || | .
PGMTNMEVLQQVDRPEGYRMPCPPNCPDEYYKIMFDCWQHEPDDRPTFES
Kinase AqueK424.AA Pkinase_Tyr 375-622 39 7.5e-89 301.54 Pfam 1-270 (270) Show / Hide 
Range on Protein: 375-622
Range on HMM: 1-270/270
Sequence Identity: 39% (106 aa)

IKFEQCINAGRFGETWKGNCK-----GKGPVMIKTN--IATDIT--QETFIEEAKILVKF-YHKNIISLYGVCI-EDYP--FYIVTEPMNG-NLKDYLTT
|.| . . .| ||| .|| .|     .| || .|.    |..    .| |..||||. .. .|.||..|||||. .. |   |||.| | . .|.||| .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

----KYLVTSAELVDIAIQVTKGMMYLGEQGYIHCDLRAENILLRDHNTVKIANFHLAQHL-NGSKY-STVEGTKLAIRWTAPEAYTLNQLSIKSDVWSF
    |  .|  .|.....|. ||| || ....|| ||.| |.|. . |.|||. | ||  . | . |  . .|.|| |.|.|||.   .  ..|||||||
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWSF

GILLWELVTKGKEP-YSGMTDEDVKEAV-SKGYHMLLPQGCPEPFKQLMLNCWKQNKDKRPSFKNIFDLL
|.|.||..| |..| | ||..|.|.|..  .|| |  |..||..  .||. ||... ..||.|. |   |
GVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase AqueK424.AA TK 375-622 19 1.4e-85 286.81 In-house 1-486 (486) Show / Hide 
Range on Protein: 375-622
Range on HMM: 1-486/486
Sequence Identity: 19% (97 aa)

IKFEQCINAGRFG---ETWKGNCKGKG--------------------------PVMIKTNIATDITQET-FIE--------------EAKILVKFY----
|.... . .| ||   | .||  .|..                          || .|.  ..| .... |..              || .. ..     
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HKNIISLYGVCIED------------YPFYIVTEPMN-GN----LKDYLTTKYL---------------------------------------------
 |.||..||||| ..             |..||.| |. |.    |.||| ..                                               
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------VTSAELVDIAIQVTKGMMYLGEQ------GYIHCDLRAENILLRDHNT-----------VKIANFH---
                               .| ..|. .. |. .|| || ..      ...| || | |.|. ..|.           .||| |    
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----LAQHL-NGSKYSTVE------------------------GTKLAIRWTAPEAYT---------LNQLSIKSDVWSFGILLWELVTKGKEPYSG-M
     ||  . ... | ...                        |.|| |||.|||. .          .  ..||||||||.|.||..| |.||| | |
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

TD---------EDVKEAVSKG--------------YHMLLPQGCP--------------EPFKQLMLNCWKQNKDKRPSFKNIFDLL
..         ..| | . .|              . |  |..||              | . .||. ||. . ..||.|. . . |
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase AqueK424.AA Frk 375-626 40 3.7e-80 272.61 In-house 1-260 (260) Show / Hide 
Range on Protein: 375-626
Range on HMM: 1-260/260
Sequence Identity: 40% (106 aa)

IKFEQCINAGRFGETWKGNCKGKGPVMIKTNIATDITQETFIEEAKILVKFYHKNIISLYGVCIEDYPFYIVTEPMNGN-LKDYLT----TKYLVTSAEL
|.. . . .|.||| | |    . || .||  .  .  . |. ||.|. |  |  .|.|| ||  . | ||.|| |  . |..||     .   .   .|
IQLIRRLGSGQFGEVWEGLWNNTTPVAVKTLKPGTMDPNDFLREAQIMKKLRHPKLIQLYAVCTVEEPIYIITELMRHGSLQEYLQAINDKGRQCQMQQL

VDIAIQVTKGMMYLGEQGYIHCDLRAENILLRDHNTVKIANFHLAQ-HLNGSK--YSTVEGTKLAIRWTAPEAYTLNQLSIKSDVWSFGILLWELVTKGK
||.| ||  || || .| ||| || | |.|. .|| .||| | ||   .   .  | .  | .. |.||||||   |. .|||||||||||| |..| |.
VDMAAQVAAGMAYLESQNYIHRDLAARNVLVGEHNICKIADFGLARVLMKDNEDIYESRHGARFPIKWTAPEAANYNKFTIKSDVWSFGILLTEIITYGR

EPYSGMTDEDVKEAVSKGYHMLLPQGCPEPFKQLMLNCWKQNKDKRPSFKNIFDLLMKYD
 ||.|||. .| . |..|| |  | .||. . ..||.||... .||| |  .   | .| 
MPYPGMTNAEVLQMVDHGYRMPQPPNCPQQLYEIMLECWHSDPMKRPTFETLQWKLEDYF
Kinase AqueK424.AA SrcA 375-622 46 1.8e-79 250.71 In-house 1-250 (250) Show / Hide 
Range on Protein: 375-622
Range on HMM: 1-250/250
Sequence Identity: 46% (116 aa)

IKFEQCINAGRFGETWKGNCKGKGPVMIKTNIATDITQETFIEEAKILVKFYHKNIISLYGVCIEDYPFYIVTEPMN-GNLKDYL---TTKYLVTSAELV
|. |. .  | ||| | |   |.  | |||     .  |.|.|||.|. |  |  .. || |  |. | ||||| |. | | |.|   . |||    .||
IRLERRLGQGCFGEVWMGTWNGTTKVAIKTLKPGTMSPEAFLEEAQIMKKLRHDKLVQLYAVVSEE-PIYIVTEYMCKGSLLDFLKDEEGKYLKL-PQLV

DIAIQVTKGMMYLGEQGYIHCDLRAENILLRDHNTVKIANFHLAQHLNGSKYSTVEGTKLAIRWTAPEAYTLNQLSIKSDVWSFGILLWELVTKGKEPYS
|.| || .|| |.    ||| |||| |||  ..   ||| | ||  ..   |    |.|  |.||||||       |||||||||||| ||||||. || 
DMAAQVAEGMAYMERMNYIHRDLRAANILVGENLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYP

GMTDEDVKEAVSKGYHMLLPQGCPEPFKQLMLNCWKQNKDKRPSFKNIFDLL
|| . .| | | .||||  ||.|||   .||  ||... . || |  .   |
GMNNREVLEQVERGYHMPCPQDCPESLHELMCQCWRKDPEERPTFEYLQSFL
Kinase AqueK424.AA TyrKc 375-622 34 3e-79 270.51 SMART 1-280 (280) Show / Hide 
Range on Protein: 375-622
Range on HMM: 1-280/280
Sequence Identity: 34% (97 aa)

IKFEQCINAGRFGETWKGNCKGKGPVMIKTNIATDITQETFIEEAKILVKF--YHKNIISLYGVCIED-------YPFYIVTEPM-NGNLKDYL-TTKYL
|.... .  | ||| .||  |   .| .|.  .    .| |..||.|. |.   |.||. |||||...        | .||.| | .|.|||||  ..  
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK

VTSAELVDIAIQVTKGMMYLGEQGYIHCDLRAENILLRDHNTVKIANFHLAQHLNGS-------KYSTVE---GTK--LAIRWTAPEAYTLNQLSIKSDV
.. ..|.....|. .|| || ....|| || | |.|. . .||||. | |.  .          .| ..    |.|  | |||.|||.   .  ..||||
LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDV

WSFGILLWELVTKGKEPYSG-----MTDEDVKEAVSKGYHMLLPQG--------CPEPFKQLMLNCWKQNKDKRPSFKNIFDLL
||||...||. | |..||.|     |....| | | .|| |  |.         ||.   |.|. ||. . ..||.|..| ...
WSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase AqueK424.AA Src-Echino1 375-622 39 1.4e-74 254.13 In-house 1-252 (252) Show / Hide 
Range on Protein: 375-622
Range on HMM: 1-252/252
Sequence Identity: 39% (99 aa)

IKFEQCINAGRFGETWKGNCKGKGPVMIKTNIATDITQETFIEEAKILVKFYHKNIISLYGVCIEDYPFYIVTEPM-NGNLKDYLTTKYLV--TSAELVD
 .... |  |..|| |||  .|  || .||     ...  |. || .. |  |..|. .| || .  | ||||| | ||||.|||          ..|.|
LRMDKKIGKGHCGEVWKGVWNGNTPVAVKTLKEKTMSPADFLAEANVMKKCRHEGIVQIYAVCSDKEPIYIVTELMSNGNLQDYLKRGKCKHVKMTTLID

IAIQVTKGMMYLGEQGYIHCDLRAENILLRDHNTVKIANFHLAQHLNGSKYSTVEGTKLAIRWTAPEAYTLNQLSIKSDVWSFGILLWELVTKGKEPYSG
.  ..  || |||.. ..| || | |.|. . | .|||.| ||. ..   | . .| || |.||||||    .  |||||||||||. |.|| |. || |
MGAHIASGMDYLGSKNVVHRDLAARNVLVGKGNVCKIADFGLARMMQKDVYCGKQGAKLPIKWTAPEAALYGRFTIKSDVWSFGILMTEMVTFGRYPYPG

MTDEDVKEAVSKGYHMLLPQGCPEPFKQL-MLNCWKQNKDKRPSFKNIFDLL
|.. .| . | .|| |  .. ||.   .. |. || ..  .|| |. . | .
MMNREVLDQVDRGYRMPKMHHCPDSLYMMCMMKCWHKDPQQRPTFEFLHDFF
Kinase AqueK424.AA Abl 375-622 39 1.3e-73 244.79 In-house 1-252 (252) Show / Hide 
Range on Protein: 375-622
Range on HMM: 1-252/252
Sequence Identity: 39% (99 aa)

IKFEQCINAGRFGETWKGNCKGKGP-VMIKTNIATDITQETFIEEAKILVKFYHKNIISLYGVCIEDYPFYIVTEPM-NGNLKDYL--TTKYLVTSAELV
|  .. .  | .|| ..|  |  .  | .||     .  . |..|| |. .  |.|.. | |||  . ||||.|| | .||| |||  . . ....  |.
IMMKHKLGGGQYGEVYEGVWKRHDCTVAVKTLKEDTMEVHEFLKEAAIMKEMKHPNLVQLLGVCTREPPFYIITEFMCYGNLLDYLRECDREELPAVVLL

DIAIQVTKGMMYLGEQGYIHCDLRAENILLRDHNTVKIANFHLAQHLNGSKYSTVEGTKLAIRWTAPEAYTLNQLSIKSDVWSFGILLWELVTKGKEPYS
 .| |.. || || .. .|| || | | |. .|. ||.| | ||  ...  |    | |  |.|||||.   |. |.||||| ||.||||. | |  || 
YMATQIASGMSYLEKRHFIHRDLAARNCLVGEHHIVKVADFGLARMMKDDTYTAHAGAKFPIKWTAPESLAYNKFSSKSDVWAFGVLLWEIATYGMSPYP

GMTDEDVKEAVSKGYHMLLPQGCPEPFKQLMLNCWKQNKDKRPSFKNIFDLL
|.  ..| . . ||| |  |.|||.   .||..||. ..  |||||.|   .
GIDLSHVYHKLEKGYRMERPEGCPPKVYELMRQCWQWSHTDRPSFKEIHHAM
Kinase AqueK424.AA SrcB 375-623 39 4.3e-72 243.14 In-house 1-251 (251) Show / Hide 
Range on Protein: 375-623
Range on HMM: 1-251/251
Sequence Identity: 39% (100 aa)

IKFEQCINAGRFGETWKGNCKGKGPVMIKTNIATDITQETFIEEAKILVKFYHKNIISLYGVCIEDYPFYIVTEPM-NGNLKDYLTTK--YLVTSAELVD
.|... . || ||| | |  ...  | .||     .  | |..|| .. .  |. .. || |   . | ||.|| | .| | |.| |.    ..   |.|
LKLVKKLGAGQFGEVWMGYYNNHMKVAVKTMKQGTMSPEAFLAEANVMKTLQHDRLVRLYAVVTKE-PIYIITEYMAKGCLLDFLKTDEGSKLSLPKLID

IAIQVTKGMMYLGEQGYIHCDLRAENILLRDHNTVKIANFHLAQHLNGSKYSTVEGTKLAIRWTAPEAYTLNQLSIKSDVWSFGILLWELVTKGKEPYSG
.. |.. || |. .. ||| |||| |||  .    ||| | ||  ..   |   || |  |.||||||       |||||||||||| |.|| |. || |
MSAQIAEGMAYIERMNYIHRDLRAANILVSETLCCKIADFGLARIIEDNEYTAREGAKFPIKWTAPEAINFGCFTIKSDVWSFGILLMEIVTYGRIPYPG

MTDEDVKEAVSKGYHMLLPQGCPEPFKQLMLNCWKQNKDKRPSFKNIFDLLM
||  .| .....|| |  |. |||   ..|  |||.  . || |  .   | 
MTNPEVIRNLERGYRMPRPDNCPEELYNIMMMCWKERPEERPTFDYLQSVLD
Kinase AqueK424.AA UTK 375-622 30 3.1e-70 239.49 In-house 1-296 (296) Show / Hide 
Range on Protein: 375-622
Range on HMM: 1-296/296
Sequence Identity: 30% (90 aa)

IKFEQCINAGRFGETWKGNCK------GKGPVMIKTNIATDI---TQE---TFIEEAK---ILVKFY-HKNIISLYGVCIEDYPFYIVTEPMN-GNLKDY
... ... .|.|||  |.  .      ..  | .|.. ...    ..|   .|.|||.   .. .|. | |.. |.|||  . |..|||| |  |.| .|
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSY

LTTKYL--------VTSAELVDIAIQVTKGMMYLGEQGYIHCDLRAENILLRDH-------NTVKIANFH---LAQHLN---------GSKYSTVEG-TK
| .           .|. .... | ..  || || ..|..|.|| | |.|. .|       ...|||.|    ..  .|         .| |..  . ..
LRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQDR

LAIRWTAPEAYTLN-QLSIKSDVWSFGILLWELVTKGKEPYSGMTDEDVKEAVSKG--YHMLLPQGCPEPFKQLMLNCWKQNKDKRPSFKNIFDLL
..|||.||||.| . . ..||||||||...||..| |. || ||....| ..|..|  |.|  |..||.|  .||. ||... ..||.|. . . .
WPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDFEDLVQQM
Kinase AqueK424.AA Src-Unclassified 375-622 34 4.3e-69 235.84 In-house 1-284 (284) Show / Hide 
Range on Protein: 375-622
Range on HMM: 1-284/284
Sequence Identity: 34% (99 aa)

IKFEQCINAGRFGETWKGNCKGKGPVMIKTNIAT---DITQETFI--------EEAKILVKFYHKNIISLYGVCIEDYPFYIVTEPM-NGNLKDYLTTKY
..    .  | ||| |.|  .||  | .||  .        | |         .||.|. |. | |.. ||.|| .. |.||.|| | || | ..| .  
VHLLRKLGRGQFGEVWYGKWRGKVDVAVKTMRPGHSETMSPEAFLHVKILNFCQEAQIMKKCRHQNLVHLYAVCSQEEPYYIITEYMINGSLLQWLREGG

--LVTSAEL------------VDIAIQVTKGMMYLGEQGYIHCDLRAENILLRDHN-----TVKIANFHLA--QHLNGSKYSTVEGTKLAIRWTAPEAYT
  .    ..            |||| ||  ||||| . .|.| || | |.|  . |      ||.. | ||         |    | .. . |.|||. .
GQYLHIQDMSEETGRKNVLIGVDIAAQVASGMMYLESKKYVHRDLAARNVLIGHNNSNGVPVVKVCDFGLARKKLMQDDNYCMRTGAMFPWKWMAPECFI

LNQLSIKSDVWSFGILLWELVTKGKEPYSGMTDEDVKEAVSKGYHMLLP--QGCPEPFKQ-LMLNCWKQNKDKRPSFKNIFDLL
    ||||||||.||||||. |||. || ||  . | | |. || |  |  ..||.   . .|. || .  ..|| |   .  .
YGNFSIKSDVWSYGILLWEIMTKGQTPYPGMHNREVLEHVERGYRMPKPTNHYCPDYIYEDIMKKCWHKDPQRRPTFDTLYHYF
Kinase AqueK424.AA S_TKc 375-624 23 5.8e-36 126.71 SMART 1-231 (231) Show / Hide 
Range on Protein: 375-624
Range on HMM: 1-231/231
Sequence Identity: 23% (62 aa)

IKFEQCINAGRFGETWKGNCKG-KGPVMIKTNIATDITQETFIEEAKILVKFYHKNIISLYGVCIEDYPFYIVTEPMNG---NLKDYLTTKYL------V
 .. . |  | ||. .|.  |. .  | ||         |... | .|| |  |.||. ||.|. .   .|.|.| ..|   .|.||.  .         
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF

TSAELVDIAIQVTKGMMYLGEQGYIHCDLRAENILLRDHNTVKIANFHLAQHLNGSKYSTVEGTKLAIRWTAPEAYTLNQLSI-KSDVWSFGILLWELVT
.  .   .. |. ... |. ..| ||.||  ||||| .  ..||. | || .|                . |||     . .  |.|.||.|..|.|...
PE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLC

KGKEPYSGMTDEDVKEAVSKGYHMLLPQGCPEPFKQLMLNCWKQNKDKRPSFKNIFD-------LLMK
 |. |..  ... . . .            ....|... .|.. . .|||.   ..            
-GYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK424.AA Pkinase 375-622 23 7e-33 117.35 Pfam 1-293 (293) Show / Hide 
Range on Protein: 375-622
Range on HMM: 1-293/293
Sequence Identity: 23% (70 aa)

IKFEQCINAGRFGETWKGNCKGKG-PVMIKTNIATDITQETFIE-----EAKILVKFYHKNIISLYGVCIEDYPFYIVTEPMNG-----NLKDYLT--TK
......| .| ||. .|.  || |  | .|.    ..  .  ..     |..|. .. |.||. ||... ..   |.|.| ..|      |.||..   .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

YLV--TSAELVDIAIQVTKGMMYLGEQGYIHCDLRAENILLRDHNTV----KIANFHLAQ---HLNGSKYSTVEGTKLAIRWTAPEAYT-LNQLSIKSDV
  .  .  |. ... |. .|. |. ..| ||.||  ||||. .....    ||. | ||    . |.| ..|. ||   ... |||     .  . |.|.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGT---PWYMAPEVIRGGQYYGPKVDM

WSFGILLWELVTKGKEPYSGM----TDEDVKEAVSKGYHMLLPQGCP-----------------------EPFKQLMLNCWKQNKDKRPSFKNIFDL--L
||.|..|.|... |. |..|     .  | .. . .  .  |.  .|                       |..|... .|....  |||... |.    .
WSCGCILYEMLC-GRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF