Gene AqueK434 (A.queenslandica)

AqueK434

Species: A.queenslandica
Alias: AqueK434
External Links:
Annotation:

Classification

Group: TK
Family: Src
Subfamily: Src-Aque1

Sequence

Name Sequence Type Origin Length Description Download
AqueK434.AA Protein None 1085 None Fasta, JSON
AqueK434.kin_dom Protein Kinase Domain None 249 None Fasta, JSON

Protein domain

Protein domains of AqueK434.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Death AqueK434.AA Death 32-104 21 6.5e-05 18.75 Pfam 13-87 (87) Show / Hide 
Range on Protein: 32-104
Range on HMM: 13-87/87
Sequence Identity: 21% (16 aa)

PEAKWFEFGLNLGLLYPTLEAIDA-NHRGNTSRCLMECLSKWLSK-AHHPTWQTLANALRKLEAKAVAKNIEEIM
| ..| ...  ||. .  .. |   .......   .. | ||  .     | ..|. ||||..   .|..|....
PGKDWRRLARKLGMSDNEIDQIEHDQNPHDLRSQTYQMLWKWEQRHGKNATVDHLIEALRKMGRRDCAEKIQSWL
SH3 AqueK434.AA SH3 650-708 35 3.2e-13 51.16 SMART 1-58 (58) Show / Hide 
Range on Protein: 650-708
Range on HMM: 1-58/58
Sequence Identity: 35% (21 aa)

TVFKASYNFEAQTLDDLTLKKGEVLEVVTYDDDHRWWYMHSLHTDKEGYVPINYILPIE
 ...| |...||. |.|..|||....|.  | |  ||.    .| .||..| ||. .|.
PYVRALYDYQAQNPDELSFKKGDIITVLEKD-DDGWWKGRCNRTGQEGWFPSNYVEEID
SH3_1 AqueK434.AA SH3_1 653-701 36 3.8e-11 40.66 Pfam 1-49 (49) Show / Hide 
Range on Protein: 653-701
Range on HMM: 1-49/49
Sequence Identity: 36% (18 aa)

KASYNFEAQTLDDLTLKKGEVLEVVTYDDDHRWWYMHSLHTDKEGYVPI
.| | ..||. |.|..|||....|.  .||  ||   .. | .||..| 
VALYDYQAQQPDELSFKKGDIIHVIEKSDDWDWWKGRCNNTGQEGWFPS
SH3_2 AqueK434.AA SH3_2 651-707 17 1.9e-07 29.01 Pfam 1-68 (68) Show / Hide 
Range on Protein: 651-707
Range on HMM: 1-68/68
Sequence Identity: 17% (12 aa)

VFKASYNFEA-QTLDD-----LTLKKGEVLEVV---TYDDDHRWWYMHSL-HTDKE--GYVPINYILPI
....  .... .  ..     |..|||.|..|    ..|.|  ||. .    . ..  |..|.... ..
YYRVHCDYVPATYCNENHEPQLHFKKGDVIKVIDNGDKDWD-NWWWCWETIWGGRRMRGWFPSQWVEEC
SH2 AqueK434.AA SH2 719-795 42 8.3e-28 83.47 Pfam 1-81 (81) Show / Hide 
Range on Protein: 719-795
Range on HMM: 1-81/81
Sequence Identity: 42% (35 aa)

YYH-TVSRDEAEERLSQADTQAGTFLIRDSERDPGQYYSLSLNDGV---KIRHYCIYIVKN-QYYISPHVQFDSLNDLVHHY
.||  .|| |||..| .   . ||||.|.||. ||. |.||. |.    ...|| |   .| .|||.  ..|.||..||.||
WYHGKISRQEAERLLMNPGNPDGTFLVRESESTPGD-YTLSVRDDGPGDRVKHYRIQRTDNGGYYITGRHKFCSLQELVEHY
SH2 AqueK434.AA SH2 717-801 37 1.3e-22 82.39 SMART 1-87 (87) Show / Hide 
Range on Protein: 717-801
Range on HMM: 1-87/87
Sequence Identity: 37% (33 aa)

YIYYH-TVSRDEAEERLSQADTQAGTFLIRDSERDPGQYYSLSLNDGVKIRHYCIYIVK-NQYYISP--HVQFDSLNDLVHHYMMKADG
. .||  .||.|||. | .   . |.||.||||.   . |.||. .. |..|| |   . ..|||     ..|.|| .||.||.  ..|
QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSES-NPGDYVLSVRWKGKVKHYRIRRNDDGKYYIDETWRRKFPSL-ELVNHYQHNPLG
Kinase AqueK434.AA Src 831-1080 39 2.4e-78 265.79 In-house 1-255 (255) Show / Hide 
Range on Protein: 831-1080
Range on HMM: 1-255/255
Sequence Identity: 39% (101 aa)

IKFEQCINAGHFGETWKGNCQGKGPVIIKTNIATNITQETFIKEANILRKFYNKNIISLYGVCIEDYPFYIITAPIDQN-LKNYLI--NMIKPPTQVQLV
||... . .|.||| |.|  .|. .| .||  . .  .| | .||.|. |.  .....|| || .. |.||.|    .. |  ||      .     ||.
IKLCRKLGQGQFGEVWMGYWNGNTKVAVKTLKPGTMSPEAFLQEAQIMKKLRHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKKDGEGRHLHLPQLI

NFAIQVTDGMIYLGNQDYIHCDLRAINILLGDHNTVKIANFHLAQHLN-GKKYYSIKKYDLLTYRWTAPEGHILNRLSIKSDVWSFGILLWELATKGKEP
 .| || .|| ||. . ||| ||.| |.| |..| .|.| | ||. .  ..  |. ..   . ..|||||    .| .||||||||||||.|. |.|. |
DMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLARLIKEDDDEYCARHGAKFPIKWTAPEAINYGRFTIKSDVWSFGILLTEIVTYGRVP

YPGMTDEEVKEAVSKGDHMPIPQDCP-ELFKQLMINCWKQNEDQRPNFIHIFNIL
||||| .|| ..|..| .|| |. || ||..|.|  ||..  .||| |  ... |
YPGMTNHEVLQQVERGYRMPCPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL
Kinase AqueK434.AA SFK-Src 831-1073 39 3.9e-77 228.01 In-house 1-248 (259) Show / Hide 
Range on Protein: 831-1073
Range on HMM: 1-248/259
Sequence Identity: 39% (98 aa)

IKFEQCINAGHFGETWKGNCQGKGPVIIKTNIATNITQETFIKEANILRKFYNKNIISLYGVCIEDYPFYIITAPIDQ-NLKNYLIN-MIKPPTQVQLVN
|. |.   .| ||. |||   ..  | .||     . .| | .|| ...|    | | || ||    | ||||  .    |  || .   .  .  ||| 
IRLEKKLGSGQFGDVWKGRWNNTTEVAVKTLKPGAMSAEEFLQEAQVMKKLRHPNLIQLYAVCTDGEPIYIITELMKYGSLLDYLHEPHGRSLRMPQLVD

FAIQVTDGMIYLGNQDYIHCDLRAINILLGDHNTVKIANFHLAQHLNGKKY-YSIKKYDLLTYRWTAPEGHILNRLSIKSDVWSFGILLWELATKGKEPY
 | ||  || ||  | ..| || | |.| || |..|.. | ..  |  .   |  ..      .|||||    || ||||||||||||. |. | |  ||
MAAQVAHGMAYLEAQNFVHRDLAARNVLVGDNNVCKVGDFGMSRVLAQDDEGYTAHEGAKFPIKWTAPEAMNMNRFSIKSDVWSFGILMMEIVTYGRIPY

PGMTDEEVKEAVSK--GDHMPIPQDCPELFKQLMINCWKQNEDQRPNF
||||  ||   | .  |  || |. ||. . ..|..||... | || |
PGMTNMEVLQQVDRPEGYRMPCPPNCPDEYYKIMFDCWQHEPDDRPTF
Kinase AqueK434.AA Pkinase_Tyr 831-1080 35 1.3e-76 260.12 Pfam 1-270 (270) Show / Hide 
Range on Protein: 831-1080
Range on HMM: 1-270/270
Sequence Identity: 35% (97 aa)

IKFEQCINAGHFGETWKGNCQ-----GKGPVIIKTN--IATNIT--QETFIKEANILRKF-YNKNIISLYGVCI-EDYP--FYIITAPIDQ-NLKNYLIN
|.| . . .|.||| .|| .      .| || .|.    |.     .| |..||.|.... ...||..|||||. .. |   ||..      .|..|| .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

M---IKPPTQVQLVNFAIQVTDGMIYLGNQDYIHCDLRAINILLGDHNTVKIANFHLAQHLNGKKYY-SIKKYDLLTYRWTAPEGHILNRLSIKSDVWSF
     .|.|  .|.....|. .|| || .. .|| ||.| |.|... |.|||. | ||  .  . ||   ..   |  .|.|||    .. ..|||||||
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWSF

GILLWELATKGKEP-YPGMTDEEVKEAV-SKGDHMPIPQDCPELFKQLMINCWKQNEDQRPNFIHIFNIL
|.|.||. | |..| ||||..|||.|..  .|  ||.|..||.   .||  ||... ..|| |  | ..|
GVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase AqueK434.AA Frk 831-1073 40 1.3e-70 240.87 In-house 1-249 (260) Show / Hide 
Range on Protein: 831-1073
Range on HMM: 1-249/260
Sequence Identity: 40% (101 aa)

IKFEQCINAGHFGETWKGNCQGKGPVIIKTNIATNITQETFIKEANILRKFYNKNIISLYGVCIEDYPFYIITAPIDQN-LKNYLINMIKPPTQVQL---
|.. . . .| ||| | |    . || .||  .  .  . |..|| |..|     .|.|| ||  . | ||||  . .. |..||  . .   |.|.   
IQLIRRLGSGQFGEVWEGLWNNTTPVAVKTLKPGTMDPNDFLREAQIMKKLRHPKLIQLYAVCTVEEPIYIITELMRHGSLQEYLQAINDKGRQCQMQQL

VNFAIQVTDGMIYLGNQDYIHCDLRAINILLGDHNTVKIANFHLAQHLNGKKY--YSIKKYDLLTYRWTAPEGHILNRLSIKSDVWSFGILLWELATKGK
|. | ||  || || .| ||| || | |.|.|.|| .||| | ||  |   .   |  .    .  .|||||    |. .|||||||||||| |. | |.
VDMAAQVAAGMAYLESQNYIHRDLAARNVLVGEHNICKIADFGLARVLMKDNEDIYESRHGARFPIKWTAPEAANYNKFTIKSDVWSFGILLTEIITYGR

EPYPGMTDEEVKEAVSKGDHMPIPQDCPELFKQLMINCWKQNEDQRPNF
 ||||||. || . |..|  || | .||. . ..|..||... ..|| |
MPYPGMTNAEVLQMVDHGYRMPQPPNCPQQLYEIMLECWHSDPMKRPTF
Kinase AqueK434.AA SrcA 831-1080 42 9.7e-69 216.18 In-house 1-250 (250) Show / Hide 
Range on Protein: 831-1080
Range on HMM: 1-250/250
Sequence Identity: 42% (108 aa)

IKFEQCINAGHFGETWKGNCQGKGPVIIKTNIATNITQETFIKEANILRKFYNKNIISLYGVCIEDYPFYIITAPIDQN-----LKNYLINMIKPPTQVQ
|. |. .  | ||| | |   |.  | |||     .  |.|..|| |..|     .. || |  |. | ||.|  . .      ||.     .| |   |
IRLERRLGQGCFGEVWMGTWNGTTKVAIKTLKPGTMSPEAFLEEAQIMKKLRHDKLVQLYAVVSEE-PIYIVTEYMCKGSLLDFLKDEEGKYLKLP---Q

LVNFAIQVTDGMIYLGNQDYIHCDLRAINILLGDHNTVKIANFHLAQHLNGKKYYSIKKYDLLTYRWTAPEGHILNRLSIKSDVWSFGILLWELATKGKE
||  | || .|| |.    ||| |||| ||| |..   ||| | ||  ..    |  ..      .|||||  .  |  |||||||||||| || |||. 
LVDMAAQVAEGMAYMERMNYIHRDLRAANILVGENLICKIADFGLARLIEDNE-YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRV

PYPGMTDEEVKEAVSKGDHMPIPQDCPELFKQLMINCWKQNEDQRPNFIHIFNIL
||||| . || | | .| ||| ||||||   .||. ||... . || |  .   |
PYPGMNNREVLEQVERGYHMPCPQDCPESLHELMCQCWRKDPEERPTFEYLQSFL
Kinase AqueK434.AA TyrKc 831-1080 32 2.8e-67 230.72 SMART 1-280 (280) Show / Hide 
Range on Protein: 831-1080
Range on HMM: 1-280/280
Sequence Identity: 32% (92 aa)

IKFEQCINAGHFGETWKGNCQGKGPVIIKTNIATNITQETFIKEANILRKF--YNKNIISLYGVCIED-------YPFYIITAPIDQ-NLKNYLINMIKP
|.... .  |.||| .||      .| .|.  .    .| |..||.|..|.   ..||. |||||...        | .|..   .  .||.|| .  . 
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK

PTQVQLVNFAIQVTDGMIYLGNQDYIHCDLRAINILLGDHNTVKIANFHLAQHLNGK-------KYYSI----KKYDLLTYRWTAPEGHILNRLSIKSDV
 .  .|..|..|. .|| ||  . .|| || | |.|.|. .||||. | |.  .  .       .||.      . ..| .||.|||    .. ..||||
LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDV

WSFGILLWELATKGKEPYPG-----MTDEEVKEAVSKGDHMPIPQD--------CPELFKQLMINCWKQNEDQRPNFIHIFNIL
||||...||. | |..||||     |...|| | | .|. ||.|..        ||.   |.|  ||. . ..||.|  |  ..
WSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase AqueK434.AA TK 831-1080 19 1.5e-66 221.86 In-house 1-486 (486) Show / Hide 
Range on Protein: 831-1080
Range on HMM: 1-486/486
Sequence Identity: 19% (93 aa)

IKFEQCINAGHFG---ETWKGNCQGKG--------------------------PVIIKTNIAT-NITQETFIK--------------EANILRKFY----
|.... . .|.||   | .||  .|..                          || .|.  .. . .|| |.               ||... ..     
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-NKNIISLYGVCIED------------YPFYIITAPID-QN----LKNYLINMIKP--------------------------------------------
  .||..||||| ..             |..|..   .  .    |..|| .  ..                                            
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------PTQVQLVNFAIQVTDGMIYLGNQ------DYIHCDLRAINILLGDHNT-----------VKIANFH---
                               .|  ||. .. |. .|| ||  .       ..| || | |.|.|..|.           .||| |    
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----LAQHLNGKKYYSIKK------------------------YDLLTYRWTAPEGHI---------LNRLSIKSDVWSFGILLWELATKGKEPYPG-M
     ||  .. ...|  |.                         . |  ||.|||             .. ..||||||||.|.||. | |.|||.| |
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

TD---------EEVKEAVSK------------GDHMPIP--QDCP--------------ELFKQLMINCWKQNEDQRPNFIHIFNIL
..         .|| | . .            |. |. |  ..||              |.. .||  ||. . ..||.|  . . |
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase AqueK434.AA Src-Echino1 831-1080 37 2.6e-65 223.27 In-house 1-252 (252) Show / Hide 
Range on Protein: 831-1080
Range on HMM: 1-252/252
Sequence Identity: 37% (95 aa)

IKFEQCINAGHFGETWKGNCQGKGPVIIKTNIATNITQETFIKEANILRKFYNKNIISLYGVCIEDYPFYIITAPIDQ-NLKNYL-INMIKPPTQVQLVN
 .... |  ||.|| |||  .|  || .||     ...  |. |||...|   ..|. .| || .  | ||.|  . . ||..||  .  |     .|..
LRMDKKIGKGHCGEVWKGVWNGNTPVAVKTLKEKTMSPADFLAEANVMKKCRHEGIVQIYAVCSDKEPIYIVTELMSNGNLQDYLKRGKCKHVKMTTLID

FAIQVTDGMIYLGNQDYIHCDLRAINILLGDHNTVKIANFHLAQHLNGKKYYSIKKYDLLTYRWTAPEGHILNRLSIKSDVWSFGILLWELATKGKEPYP
   ..  || ||| ....| || | |.|.|. | .|||.| ||. .. |  |  |.   |  .|||||  .  |  |||||||||||. |. | |. |||
MGAHIASGMDYLGSKNVVHRDLAARNVLVGKGNVCKIADFGLARMMQ-KDVYCGKQGAKLPIKWTAPEAALYGRFTIKSDVWSFGILMTEMVTFGRYPYP

GMTDEEVKEAVSKGDHMPIPQDCPELFKQL-MINCWKQNEDQRPNFIHIFNIL
||.. || . | .|  || ...||.   .. |. || ..  ||| | .. . .
GMMNREVLDQVDRGYRMPKMHHCPDSLYMMCMMKCWHKDPQQRPTFEFLHDFF
Kinase AqueK434.AA Abl 831-1080 35 1.4e-59 197.2 In-house 1-252 (252) Show / Hide 
Range on Protein: 831-1080
Range on HMM: 1-252/252
Sequence Identity: 35% (91 aa)

IKFEQCINAGHFGETWKGNCQGKGPVI-IKTNIATNITQETFIKEANILRKFYNKNIISLYGVCIEDYPFYIITAPIDQ-NLKNYLINMIKPP-TQVQLV
|  .. .  | .|| ..|  .  . .. .||    ..  . |.||| |...   .|.. | |||  . ||||||  . . || .|| .  .   . | |.
IMMKHKLGGGQYGEVYEGVWKRHDCTVAVKTLKEDTMEVHEFLKEAAIMKEMKHPNLVQLLGVCTREPPFYIITEFMCYGNLLDYLRECDREELPAVVLL

NFAIQVTDGMIYLGNQDYIHCDLRAINILLGDHNTVKIANFHLAQHLNGKKYYSIKKYDLLTYRWTAPEGHILNRLSIKSDVWSFGILLWELATKGKEPY
  | |.. || || ....|| || | | |.|.|. ||.| | ||  ...   |  .       .|||||.   |. |.||||| ||.||||.|| |  ||
YMATQIASGMSYLEKRHFIHRDLAARNCLVGEHHIVKVADFGLARMMKD-DTYTAHAGAKFPIKWTAPESLAYNKFSSKSDVWAFGVLLWEIATYGMSPY

PGMTDEEVKEAVSKGDHMPIPQDCPELFKQLMINCWKQNEDQRPNFIHIFNIL
||.  ..| . . ||  |  |. ||.   .|| .||. ..  || | .| . .
PGIDLSHVYHKLEKGYRMERPEGCPPKVYELMRQCWQWSHTDRPSFKEIHHAM
Kinase AqueK434.AA SrcB 831-1081 35 6.9e-58 194.37 In-house 1-251 (251) Show / Hide 
Range on Protein: 831-1081
Range on HMM: 1-251/251
Sequence Identity: 35% (92 aa)

IKFEQCINAGHFGETWKGNCQGKGPVIIKTNIATNITQETFIKEANILRKFYNKNIISLYGVCIEDYPFYIITAPIDQNLKNYLINMIKPPTQV-----Q
.|... . || ||| | |  ...  | .||     .  | |..|||....   . .. || |   . | ||||  ..   |  |.  .| .        .
LKLVKKLGAGQFGEVWMGYYNNHMKVAVKTMKQGTMSPEAFLAEANVMKTLQHDRLVRLYAVVTKE-PIYIITEYMA---KGCLLDFLKTDEGSKLSLPK

LVNFAIQVTDGMIYLGNQDYIHCDLRAINILLGDHNTVKIANFHLAQHLNGKKYYSIKKYDLLTYRWTAPEGHILNRLSIKSDVWSFGILLWELATKGKE
|. .. |...|| |. .. ||| |||| |||  .    ||| | ||  ..    |  .       .|||||        |||||||||||| |. | |. 
LIDMSAQIAEGMAYIERMNYIHRDLRAANILVSETLCCKIADFGLARIIEDNE-YTAREGAKFPIKWTAPEAINFGCFTIKSDVWSFGILLMEIVTYGRI

PYPGMTDEEVKEAVSKGDHMPIPQDCPELFKQLMINCWKQNEDQRPNFIHIFNILY
||||||  || .....|  || |. |||   ..|. |||.  ..|| | ..  .| 
PYPGMTNPEVIRNLERGYRMPRPDNCPEELYNIMMMCWKERPEERPTFDYLQSVLD
Kinase AqueK434.AA TK-Unique 831-1080 27 2.6e-56 192.65 In-house 1-294 (294) Show / Hide 
Range on Protein: 831-1080
Range on HMM: 1-294/294
Sequence Identity: 27% (81 aa)

IKFEQCINAGHFGETWKGNCQGKG-------PVIIKTNIATNITQE--TFIKEANILRKFY-NKNIISLYGVCIEDY-PFYIITAPIDQN-LKNYLI---
..... |  | ||. |.|   |.         |..|.. . .  ..   | ||......    .||....|.|...  |..||  .. .  | .||    
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR

-------------------NMIKPPTQVQ---LVNFAIQVTDGMIYLGNQDY--IHCDLRAINILLGDHNTVKIANFHLAQHLN-GKKYYSIKKYDLLTY
                   ....... ..   |..||.|.  || ||  | .  .| || | |.||......||..| .| ... ...| .....  . .
PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMCSQGRIPI

RWTAPEGHI--LNRL-SIKSDVWSFGILLWELATKGKEPYPGMTDEEVKEAVSKGDHMPIPQDC-PELFKQLMINCWKQNEDQRPNFIHIFNIL
|| |||      .   ..||||||||.|.||..| |. ||||| .... |.. .|. || |. | .. . .||..||. ....||.|  | ..|
RWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYRMPQPEHCCSHEMYNLMKSCWQWEPEERPSFRQIKHRL
Kinase AqueK434.AA Src-Unclassified 927-1080 41 3.1e-43 146.08 In-house 122-284 (284) Show / Hide 
Range on Protein: 927-1080
Range on HMM: 122-284/284
Sequence Identity: 41% (67 aa)

VNFAIQVTDGMIYLGNQDYIHCDLRAINILLGDHN-----TVKIANFHLA-QHLNGKKYYSIKKYDLLTYRWTAPEGHILNRLSIKSDVWSFGILLWELA
|  | ||  || ||    |.| || | |.| |. |      ||.. | ||   | .   |  ..   .   |.|||  |    ||||||||.||||||..
VDIAAQVASGMMYLESKKYVHRDLAARNVLIGHNNSNGVPVVKVCDFGLARKKLMQDDNYCMRTGAMFPWKWMAPECFIYGNFSIKSDVWSYGILLWEIM

TKGKEPYPGMTDEEVKEAVSKGDHMPIP--QDCPELFKQ-LMINCWKQNEDQRPNFIHIFNIL
|||. |||||  .|| | |. |  || |  . ||.   . .|  || .  ..|| |   .. .
TKGQTPYPGMHNREVLEHVERGYRMPKPTNHYCPDYIYEDIMKKCWHKDPQRRPTFDTLYHYF
Kinase AqueK434.AA S_TKc 831-1082 21 8.9e-24 86.23 SMART 1-231 (231) Show / Hide 
Range on Protein: 831-1082
Range on HMM: 1-231/231
Sequence Identity: 21% (57 aa)

IKFEQCINAGHFGETWKGNCQG-KGPVIIKTNIATNITQETFIKEANILRKFYNKNIISLYGVCIEDYPFYIITAPIDQ---NLKNYLINMIKPP-----
 .. . |  | ||. .|.   . .  | ||         |....| .||.|   .||. ||.|. .   .|...  .|.   .|. |. .. ...     
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF

TQVQLVNFAIQVTDGMIYLGNQDYIHCDLRAINILLGDHNTVKIANFHLAQHLNGKKYYSIKKYDLLTYRWTAPEGHILNRLSI-KSDVWSFGILLWELA
.  .   .. |. ... |. ..  ||.||   |||| .  ..||. | || .|         .    |  . |||  .|   .  |.|.||.|..|.|..
PE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPE--VL-GYGKCKCDWWSCGCILYEML

TKGKEPYPGMTDEEVKEAVSKGDHMPIPQDCPELFKQLMINCWKQNEDQRPNFIHIFN-------ILYL
. |. |.|  ..... . .            .. .|... .|.. . ..||    ...         ..
C-GYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK434.AA Pkinase 831-1082 19 1.5e-14 52.54 Pfam 1-293 (293) Show / Hide 
Range on Protein: 831-1082
Range on HMM: 1-293/293
Sequence Identity: 19% (58 aa)

IKFEQCINAGHFGETWKGNCQGKG-PVIIKTNIATNITQETFIK-----EANILRKFYNKNIISLYGVCIEDYPFYIITAPIDQ-----NLKNYLI-NMI
......| .| ||. .|.  .| |  | .|.    ..  .  .      |. |....  .||. ||... ..   |...   .       |. |.   . 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

KPP--TQVQLVNFAIQVTDGMIYLGNQDYIHCDLRAINILLGDHNTV----KIANFHLAQHLNGKKYYSIKKYDLL--TYRWTAPEGHI-LNRLSIKSDV
..   .  .. ... |.  |. |. ..  ||.||   |||. .....    ||. | || ...   | .   .. .  |... ||| .   .  . |.|.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD---Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDM

WSFGILLWELATKGKEPYPGM----TDEEVKEAVSKGDHMPIPQDCP-----------------------ELFKQLMINCWKQNEDQRPNFIHIFNILYL
||.|..|.|... |. |.||     .  . .. . .  . |.. |.|                       | .|... .|....  .||.. .|..  ..
WSCGCILYEMLC-GRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase AqueK434.AA Src-Unclassified 831-903 32 3.6e-12 37.98 In-house 1-84 (284) Show / Hide 
Range on Protein: 831-903
Range on HMM: 1-84/284
Sequence Identity: 32% (27 aa)

IKFEQCINAGHFGETWKGNCQGKGPVIIKTNIAT---NITQETFI--------KEANILRKFYNKNIISLYGVCIEDYPFYIIT
..    .  | ||| |.|   ||  | .||  .        | |         .||.|. |.   |.. ||.|| .. |.||||
VHLLRKLGRGQFGEVWYGKWRGKVDVAVKTMRPGHSETMSPEAFLHVKILNFCQEAQIMKKCRHQNLVHLYAVCSQEEPYYIIT