Gene AqueK458 (A.queenslandica)

AqueK458

Species: A.queenslandica
Alias: AqueK458
External Links:
Annotation:

Classification

Group: TK
Family: TK-Unique

Sequence

Name Sequence Type Origin Length Description Download
AqueK458.AA Protein None 1105 None Fasta, JSON
AqueK458.kin_dom Protein Kinase Domain None 365 None Fasta, JSON

Protein domain

Protein domains of AqueK458.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase AqueK458.AA TK 553-742 15 6.7e-33 107.04 In-house 95-486 (486) Show / Hide 
Range on Protein: 553-742
Range on HMM: 95-486/486
Sequence Identity: 15% (60 aa)

MQG--LEHVNILPLLGLSIEDNCV-----------PIAIYPLTEYGN----LHFTLEMCRLLPHENPLSP------------------------------
|.   ..| ||. |.| . .. ..           .. .  . ..|.    |.  |  ||   .... .|                              
MCHSLGHHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPC

-------------------------------------FTIDLKINFSYQLSSAMTFLADK------KVILQDLALRNCWLDANFV-----------LKLS
                                     .|   .. ...|....| .|..|      ...  ||| ||| .. | |            |..
PEEQDYDDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIA

DGA--------LFQDFYP--ECYT--------------------------------------SIKGA-----------------WSFGIVVWEIFSVAKE
|          |  | |.  . |.                                      ....                  ||||...||||. ..|
DFGLSRQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQE

PYLD-IPN---------KSITSHLMMDGRL-----------GSPS--DDCP--------------DRINSLLSSCWHKRGEERPRFSFINETL
||   ..|         . .  .| . |||             .   ..||              . .  |. .|||.  |.||.|| . | |
PYYGGMSNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase AqueK458.AA Pkinase_Tyr 671-742 39 1.7e-20 70.06 Pfam 198-270 (270) Show / Hide 
Range on Protein: 671-742
Range on HMM: 198-270/270
Sequence Identity: 39% (29 aa)

WSFGIVVWEIFSVAKEP-YLDIPNKSITSHLMMDGRLGSPSDDCPDRINSLLSSCWHKRGEERPRFSFINETL
||||.. ||||.  ..| | ...|  .  ..  ||.   . ..||| | .|. .|||.  |.||.|| | | |
WSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase AqueK458.AA Ryk 553-655 29 1.8e-19 57.99 In-house 68-182 (292) Show / Hide 
Range on Protein: 553-655
Range on HMM: 68-182/292
Sequence Identity: 29% (34 aa)

MQGLE-HVNILPLLGLS--------IEDNCVPIAIYPLTE-YGNLHFTLEMCRLLPHENPLSPFTIDLKINFSYQLSSAMTFLADKKVILQDLALRNCWL
..|.  | ||||.|. .        |||   |  .|| .   |||   |  ||. . ... .  |..|   .  |....| .|. . ..  |.| ||| .
LYGISPHQNILPVLHVCSFGRFDRPIEDHDPPFVCYPHMNNWGNLKQFLQDCRHDKPKCHQAISTHQL-VHMAIQITMGMMHLHKHRIVHKDIATRNCVI

DAN---FVLKLSDGAL
|       .|..| ||
DEQNGRLQVKICDSAL
Kinase AqueK458.AA Eph 664-742 36 4.8e-18 57.08 In-house 187-264 (264) Show / Hide 
Range on Protein: 664-742
Range on HMM: 187-264/264
Sequence Identity: 36% (29 aa)

YTSIKGAWSFGIVVWEIFSVAKEPYLDIPNKSITSHLMMDGRLGSPSDDCPDRINSLLSSCWHKRGEERPRFSFINETL
.||   .||.|||.||. |    || | .|. . .  . . || .|  |||  .  |   ||.|  ..||.|. |  .|
FTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEQGYRLPPPM-DCPEALHQLMLDCWQKDRNHRPHFQQIVSIL
Kinase AqueK458.AA UTK 671-742 34 1.6e-17 56.47 In-house 224-296 (296) Show / Hide 
Range on Protein: 671-742
Range on HMM: 224-296/296
Sequence Identity: 34% (25 aa)

WSFGIVVWEIFSVAKEPYLDIPNKSITSHLMMDGRLGSPS-DDCPDRINSLLSSCWHKRGEERPRFSFINETL
||||.|.|||.. .. || .. |  ..  ..  ||.  |. .|||...  |. .|||.  .|||.|  . ...
WSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDFEDLVQQM
TyrKc AqueK458.AA TyrKc 492-742 21 8.5e-17 48.86 SMART 1-280 (280) Show / Hide 
Range on Protein: 492-742
Range on HMM: 1-280/280
Sequence Identity: 21% (65 aa)

IAITSTFLRGTHGCLNRGILMMDRINPSSEDNVGTVMKIMTSLGDRGHREDITHFIDLTTSMQGL--EHVNILPLLGLSIEDN------CVPIAIYPLTE
|    .  .|  |   .|..            .    | . .         .  |..    |  |  .| ||. |.|  ...         .  .  . .
ITLGKKLGEGAFGEVYKGTWK-----------IQVAVKMLKEDA-------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMP

YGNLHFTLEMCRLLPHENPLSPFTIDLKINFSYQLSSAMTFLADKKVILQDLALRNCWLDANFVLKLSDGALFQDFYPE-------CYTSI----KGA--
.|.|.  |  .|          .. . ...|..| .. | .|..|..|  ||| ||| ...|.. | ||  |  | | .        | .      |   
HGDLKDYLRKHRPK--------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTM

----------------------WSFGIVVWEIFSVAKEPYLD-----IPNKSITSHLMMDGRLGSPSDD-------CPDRINSLLSSCWHKRGEERPRFS
                      ||||.. ||||.  ..|| .     ..|. .  ...  .|.  | .|       ||| . .. ..|||   |.||.||
LPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFS

FINETL
 | | .
EIHECF
Kinase AqueK458.AA Musk 671-742 30 8.9e-17 51.75 In-house 212-282 (282) Show / Hide 
Range on Protein: 671-742
Range on HMM: 212-282/282
Sequence Identity: 30% (22 aa)

WSFGIVVWEIFSVAKEPYLDIPNKSITSHLMMDGRLGSPSDDCPDRINSLLSSCWHKRGEERPRFSFINETL
|..|.. ||||| |  ||. .    .  .     .|..| . ||  .  |.  || |.  .|| |  |.. .
WAYGVCLWEIFSYALQPYYGMTHEEVIYYIRQGNILSCP-ENCPQKVYQLMRRCWQKNPADRPFFCQIHHCI
Kinase AqueK458.AA TK-Unique 671-742 37 1e-14 47.3 In-house 223-294 (294) Show / Hide 
Range on Protein: 671-742
Range on HMM: 223-294/294
Sequence Identity: 37% (27 aa)

WSFGIVVWEIFSVAKEPYLDIPNKSITSHLMMDGRLGSPSDDCPDRINSLLSSCWHKRGEERPRFSFINETL
||||.. ||||.  . || ..|.|.|  ..    |.  |.  |.... .|..|||..  |||| |. |   |
WSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYRMPQPEHCCSHEMYNLMKSCWQWEPEERPSFRQIKHRL
Kinase AqueK458.AA Axl 664-740 35 1.4e-14 47.81 In-house 192-267 (267) Show / Hide 
Range on Protein: 664-740
Range on HMM: 192-267/267
Sequence Identity: 35% (27 aa)

YTSIKGAWSFGIVVWEIFSVAKEPYLDIPNKSITSHLMMDGRLGSPSDDCPDRINSLLSSCWHKRGEERPRFSFINE
|||    |.||. .|||    . ||  . |. .   |.   ||  |  || | .  |...||.   ..|| || . |
YTSKSDVWAFGVTMWEIMTRGQTPYPGVENHEMYDYLIHGHRLKQP-EDCMDELYDLMYQCWEADPKDRPSFSVLRE
Kinase AqueK458.AA TKL 671-742 29 1.4e-14 48.9 In-house 273-364 (364) Show / Hide 
Range on Protein: 671-742
Range on HMM: 273-364/364
Sequence Identity: 29% (28 aa)

WSFGIVVWEIFS--VAKEPYLDIPNKSIT------SHLMMDG----RLGSP-----------SDDCPDRINSLLSSCWHKRGEERPRFSFINETL
.||||| |||..  .   || |.|. ..         .||..    |.  |            .|||... .|.  ||.   |.|| |. | ..|
YSFGIVLWEILTRCR---PYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase AqueK458.AA Tec 671-744 33 2.8e-13 42.81 In-house 182-254 (254) Show / Hide 
Range on Protein: 671-744
Range on HMM: 182-254/254
Sequence Identity: 33% (25 aa)

WSFGIVVWEIFSVAKEPYLDIPNKSITSHLMMDGRLGSPSDDCPDRINSLLSSCWHKRGEERPRFSFINETLCS
|.||.  ||.||  | ||    |  .  |     ||  | . |...|     .||| . |||| |.   ...  
WAFGVLMWEVFSCGKMPYENMSNSEVVEHVSQGHRLYRP-HLCSMHIYQIMYHCWHEKPEERPTFQQLLRQITE
Kinase AqueK458.AA Met 671-736 38 5.9e-13 38.51 In-house 203-271 (271) Show / Hide 
Range on Protein: 671-736
Range on HMM: 203-271/271
Sequence Identity: 38% (27 aa)

WSFGIVVWEIFSVAKEPYLDIPN-KSITSHLMMD--GRLGSPSDDCPDRIN-SLLSSCWHKRGEERPRFS
||||.| || .  .  || .. |   ||  |      ||  |   ||| .   .  .|||   |.|| ||
WSFGVVMWELMTRGAPPYPHVDNWFDITHWLHQGETRRLPQP-EYCPDHLYTDVMLCCWHANPEDRPQFS
Kinase AqueK458.AA Pkinase_Tyr 553-652 27 1.9e-10 36.02 Pfam 57-154 (270) Show / Hide 
Range on Protein: 553-652
Range on HMM: 57-154/270
Sequence Identity: 27% (29 aa)

MQGL-EHVNILPLLGLSI--ED-NCVPIAIYPLTEYGNLHFTLEMCRLLPHENPLSPFTIDLKINFSYQLSSAMTFLADKKVILQDLALRNCWLDANFVL
|  |  | ||. |.|  .  .. |  .. . .. ..|.|.  |   |     ..  |.|.  ......| ...| .|..|. |  ||| ||| .. |.| 
MKQLGHHPNIVRLYGVCTDQGEPN-QIYIVMEYMPHGDLLDYLRKHR-----EDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVV

KLSD
| .|
KICD
Kinase AqueK458.AA Axl 540-660 25 1.1e-09 30.22 In-house 42-164 (267) Show / Hide 
Range on Protein: 540-660
Range on HMM: 42-164/267
Sequence Identity: 25% (32 aa)

REDITHFIDLTTSMQGLEHVNILPLLGLSIEDNC-----VPIAIYPLTEYGNLHFTLEMCRLLPHENPLSPFTIDLKINFSYQLSSAMTFLADKKVILQD
. .|  |.     |.  .| |.. |.| .|.         |. | |   .| ||  |   ||   ..|     .   . |   . . | .|. .. |  |
QSEIEEFLSEAACMKEFDHPNVMRLIGVCIQMSERQRIPKPMVILPFMKHGDLHTFLLYSRL--GDQPFY-LPLQMLVKFMVDIACGMEYLSNRNFIHRD

LALRNCWLDANFVLKLSDGALFQDFY
|| ||| |  .      |  | .  |
LAARNCMLREDMTVCVADFGLSKKIY
Kinase AqueK458.AA TK-Unique 558-652 25 2.1e-09 28.72 In-house 63-176 (294) Show / Hide 
Range on Protein: 558-652
Range on HMM: 63-176/294
Sequence Identity: 25% (29 aa)

HVNILPLLGLSIEDNCVPIAIYPLTEYGNLHFTLEMCRLL-----------------PHENPLSPFTIDLKINFSYQLSSAMTFLAD--KKVILQDLALR
| ||. .|| ....   .  |..  ..||| . |  ||                   |......| .  . ..| .|. ..| .||   ||..  ||. |
HPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCRPAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCAR

NCWLDANFVLKLSD
|. |  ..|.|..|
NVLLTEDKVCKICD
Kinase AqueK458.AA UTK 546-652 23 5.2e-09 26.97 In-house 53-168 (296) Show / Hide 
Range on Protein: 546-652
Range on HMM: 53-168/296
Sequence Identity: 23% (28 aa)

FIDLTT---SMQGLE-HVNILPLLGLSIEDNCVPIAIYPLTEY---GNLHFTLEMCRLLPHENPLSPFTIDLKINFSYQLSSAMTFLADKKVILQDLALR
|. ...    |. .. |.|.| |.|.   .      .. .|||   |.|   |  .|  | ..|.. .| . .. .... ...| .|. ....  ||| |
FMEEARELQMMKQFHWHPNVLRLVGVCTQEEP----WMIVTEYMENGDLRSYLRRHRPTPPACPHW-LTLHQRLCMAWDIARGMQYLHSCGFVHRDLAAR

NCWLDAN-------FVLKLSD
||.....        | |..|
NCLVHMHRMMWHCMMVCKIAD
Kinase AqueK458.AA Met 612-652 41 3.4e-07 19.32 In-house 107-147 (271) Show / Hide 
Range on Protein: 612-652
Range on HMM: 107-147/271
Sequence Identity: 41% (17 aa)

INFSYQLSSAMTFLADKKVILQDLALRNCWLDANFVLKLSD
| |  |    |  .| .| .  ||| ||| ||. |. |  |
IEFCHQVAKGMMYMASQKFVHRDLACRNCMLDEHFTVKVAD
S_TKc AqueK458.AA S_TKc 492-744 12 3e-06 -84.57 SMART 1-231 (231) Show / Hide 
Range on Protein: 492-744
Range on HMM: 1-231/231
Sequence Identity: 12% (37 aa)

IAITSTFLRGTHGCLNRGILMMDRINPSSEDNVGTVMKIMTSLGDRGHREDITHFIDLTTSMQGLEHVNILPLLGLSIEDNCVPIAIYPLTEYGNLHFTL
  |  .  .|. |.  ...           ..    .||.                      . .  ..||        .| | .  .  .  ..|.. .
YEILRKIGKGAFGKVYKCRHKK--------TGRIVAIKIIK--------------------EHIRREIQILKK----HHPNIVKLYDVFQD--DHLYMVM

EMCRL-------LPHENPL----SPFTIDLKINFSYQLSSAMTFLADKKVILQDLALRNCWLDANFVLKLSD---GALFQDFY--------PECYTSIKG
|.|         . ....     .||.      . ||. .|. .. ....|  ||   |  ||   ..|..|    ... . .        ||   .  .
EYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-TTFCGTPWYMAPEVL-GYGK

----AWSFGIVVWEIFSVAKEPYLDIPNKSITSHLMMDGRLGSPSDDCPDRINSLLSSCWHKRGEERPRFSFINE-------TLCS
     ||.|....| ..  . |.    .   . ....           ..   .... |..|  |.||    . .           
CKCDWWSCGCILYEMLC-GYPPFP---QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK458.AA Tec 616-652 35 2.9e-05 14.42 In-house 104-140 (254) Show / Hide 
Range on Protein: 616-652
Range on HMM: 104-140/254
Sequence Identity: 35% (13 aa)

YQLSSAMTFLADKKVILQDLALRNCWLDANFVLKLSD
.. . .|..|  ...|  ||| |||  . . | | ||
QDVCEGMAYLERHCFIHRDLAARNCLVGDQCVVKVSD
Kinase AqueK458.AA Ryk 671-691 42 9.7e-05 10.66 In-house 222-242 (292) Show / Hide 
Range on Protein: 671-691
Range on HMM: 222-242/292
Sequence Identity: 42% (9 aa)

WSFGIVVWEIFSVAKEPYLDI
||||   ||  . .. || .|
WSFGVTMWELMTLGQMPYMEI
Kinase AqueK458.AA TKL 556-652 14 0.00019 11.94 In-house 82-197 (364) Show / Hide 
Range on Protein: 556-652
Range on HMM: 82-197/364
Sequence Identity: 14% (19 aa)

LEHVNILPLLGLSIEDNCV------------PIAIYPLTEYGN-LHFTLEMCRLLPHENPLSPFTIDLKINFSYQLSSAMTFLAD--------KKVILQD
| | ||....| ... .|             .  .. . . |. ||. .                .......... ...| .|          ...|  |
LRHPNIVQFMGYCCCPPCGCVCMHPVGPWGQLCIVMEYCPGGSLLHYLH----------------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRD

LALRNCWLDANFV--------------LKLSD
|  .|. .| |.               .|..|
LKSKNILVDENWTNVSNYMYNPNADWCCKICD
Kinase AqueK458.AA Met 553-580 27 0.00141 7.27 In-house 55-83 (271) Show / Hide 
Range on Protein: 553-580
Range on HMM: 55-83/271
Sequence Identity: 27% (8 aa)

MQGLEHVNILPLLGLSIEDNC-VPIAIYP
| ...| |.| |.| ....    |. . |
MKHFDHPNVLSLIGICLDPEGHMPWVVLP
Kinase AqueK458.AA Ryk 713-742 40 0.00431 5.36 In-house 263-292 (292) Show / Hide 
Range on Protein: 713-742
Range on HMM: 263-292/292
Sequence Identity: 40% (12 aa)

CPDRINSLLSSCWHKRGEERPRFSFINETL
|||        |||   |||| |. .   |
CPDELFTVMACCWHCMPEERPTFQQLVQCL
Kinase AqueK458.AA Musk 611-652 26 0.005801 5.37 In-house 128-169 (282) Show / Hide 
Range on Protein: 611-652
Range on HMM: 128-169/282
Sequence Identity: 26% (11 aa)

KINFSYQLSSAMTFLADKKVILQDLALRNCWLDANFVLKLSD
. .   |    | .|  .. .  ||| |||    . . | .|
QLCMAKQIACGMAYLSEMMFVHRDLATRNCLINEHMDVKIAD