Gene AqueK461 (A.queenslandica)

AqueK461

Species: A.queenslandica
Alias: AqueK461
External Links:
Annotation:

Classification

Group: TK
Family: TK-Unique

Sequence

Name Sequence Type Origin Length Description Download
AqueK461.AA Protein None 438 None Fasta, JSON
AqueK461.kin_dom Protein Kinase Domain None 397 None Fasta, JSON

Protein domain

Protein domains of AqueK461.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
TyrKc AqueK461.AA TyrKc 36-421 27 5.5e-120 405.82 SMART 1-280 (280) Show / Hide 
Range on Protein: 36-421
Range on HMM: 1-280/280
Sequence Identity: 27% (113 aa)

LHFQNTIGEGQFGQVWKAQAVGIVPEDPSLNIVAVKTLKGDADFIDKEELLAELEIMKNLY-PHPNILNLLGYCTVG-------GPCYIIMEFAMYGNLR
...  ..|||.||.|.|...            ||||.|| ||    .|... |..||..|.  ||||..|.|.|| .       .| .|.||.. .|.|.
ITLGKKLGEGAFGEVYKGTWK---------IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLK

DFLRSLKNVHSSSQAIFAPFQSSSNHPMALNEGQTVDPWSLYNNIPIHYNTVLKQHLINTDYYNQHNNGIEDTQLINADTQMINADTQIVNADTQMIDVD
|.||. ..                                                                                            
DYLRKHRPK-------------------------------------------------------------------------------------------

TQMIHVDTQMSNTDIEMIDADTHMINHPLLTEKDIFNFSLQISRGMEHLQSQKCIHRDLAARNVLIAEGQILKIADFGLAKELSSK-------DYYRRLS
                             |. ||  .|..||..|||.| |..||||||||||.|..|... ||.||||.... ..       ||||  .
-----------------------------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKE

--SGK--LPARWMAVESLDDRQTHSHQSDIWSFGVVLWEICSYGDTPYKD---HGIGNTLESLLLFIKNGDRLKRPEN--------CSTDMYQLMLQCWN
  .||  || |||| |.. .  . ...||.|||||..|||..||..|| .   .    . . .. ..|.|.|...|.|        |...|||.|.|||.
HKGGKTMLPIRWMAPECI-NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQ--MMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWH

DDPKLRPNFNELVHKF
 ||. ||.|.|....|
EDPEDRPTFSEIHECF
Pkinase_Tyr AqueK461.AA Pkinase_Tyr 36-421 30 1.6e-117 398.61 Pfam 1-270 (270) Show / Hide 
Range on Protein: 36-421
Range on HMM: 1-270/270
Sequence Identity: 30% (119 aa)

LHFQNTIGEGQFGQVWKAQAVGIVPEDPSLNIVAVKTLKGDADFID--KEELLAELEIMKNLYPHPNILNLLGYCT-VGGP--CYIIMEFAMYGNLRDFL
..|  ..|||.||.|.|. . |   .|     ||||.|| .|.  .  .|....|..|||.|  ||||..|.| ||  |.|   ||.||.. .|.|.|.|
ITFGKKLGEGAFGEVYKGTWKG--DPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

RSLKNVHSSSQAIFAPFQSSSNHPMALNEGQTVDPWSLYNNIPIHYNTVLKQHLINTDYYNQHNNGIEDTQLINADTQMINADTQIVNADTQMIDVDTQM
|. .                                                                                                
RKHR------------------------------------------------------------------------------------------------

IHVDTQMSNTDIEMIDADTHMINHPLLTEKDIFNFSLQISRGMEHLQSQKCIHRDLAARNVLIAEGQILKIADFGLAKELSSKDYY-RRLSSGKLPARWM
                      . . || ||. ....||..|||.| |..||||||||||.|..|. . ||.|||||. . ..||| |  ..|||| .||
---------------------EDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWM

AVESLDDRQTHSHQSDIWSFGVVLWEICSYGDTP-YKDHGIGNTLESLLLFI-KNGDRLKRPENCSTDMYQLMLQCWNDDPKLRPNFNELVHKF
| |.. ..   ...||.|||||..|||..||..| |.    | . | .. .| ..| |...||||. ..|.||.|||. ||. || | |.....
APECINYGK-FTTKSDVWSFGVLMWEIFTYGEQPTYP----GMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase AqueK461.AA TK 257-421 27 4.1e-76 254.49 In-house 212-486 (486) Show / Hide 
Range on Protein: 257-421
Range on HMM: 212-486/486
Sequence Identity: 27% (77 aa)

LTEKDIFN-------------------FSLQISRGMEHLQSQKC------IHRDLAARNVLIAEGQI-----------LKIADFG--------LAKELSS
||.||  .                   ...||..|||.| |..|      .||||||||.|..|. .            ||||||        ||... |
LTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQGSGVLARDIYS

KDYYRRLS------------------------SGKLPARWMAVESLDDRQ--------THSHQSDIWSFGVVLWEICSYG-DTPYKDHGI------GNTL
.|.|.| |                        .|||| |||| |.|.||.        .....||.|||||..|||..||  ..| ..        | ..
DDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMSNQDVWKDG-DN

ESLLLFIKN------------GDRLKRP--ENCS--------------TDMYQLMLQCWNDDPKLRPNFNELVHKF
. .. ....            |.|. .|  ..|.              ...|.||.|||. ||. ||.| .|....
QEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase AqueK461.AA TK-Unique 257-421 41 3.9e-74 252.61 In-house 128-294 (294) Show / Hide 
Range on Protein: 257-421
Range on HMM: 128-294/294
Sequence Identity: 41% (71 aa)

LTEKDIFNFSLQISRGMEHLQS--QKCIHRDLAARNVLIAEGQILKIADFGLAKELS-SKDYYRRLSSGKLPARWMAVESLD--DRQTHSHQSDIWSFGV
...|| ..|  || .|||.|.|  .|..||||.|||||..|. ..||.|||.|....  ..| .  |.|..| |||| |||   ... |. .||.|||||
ISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMCSQGRIPIRWMAPESLKCYHGMYHTTKSDVWSFGV

VLWEICSYGDTPYKDHGIGNTLESLLLFIKNGDRLKRPENC-STDMYQLMLQCWNDDPKLRPNFNELVHKF
..|||...| .||  .|. ..   ..  |..|.|...||.| | .||.|| .||...|. ||.| ...|..
LMWEIFTLGACPY--PGMPWKD--IMECIRDGYRMPQPEHCCSHEMYNLMKSCWQWEPEERPSFRQIKHRL
Kinase AqueK461.AA FGFR 255-421 49 1.1e-73 250.58 In-house 131-293 (293) Show / Hide 
Range on Protein: 255-421
Range on HMM: 131-293/293
Sequence Identity: 49% (83 aa)

PLLTEKDIFNFSLQISRGMEHLQSQKCIHRDLAARNVLIAEGQILKIADFGLAKELSSKDYYRRLSSGKLPARWMAVESLDDRQTHSHQSDIWSFGVVLW
| ||.||   .  |. |||| | |.|||||||||||||. .. ..||.|||||    . ||||  . | ||  ||| |.|.||    ||||.||.|| ||
PNLTQKDLVSCAYQVARGMEYLASRKCIHRDLAARNVLVTDDYVMKICDFGLARDIHCIDYYRKTTNGRLPIKWMAPEALFDR-VYTHQSDVWSYGVLLW

EICSYGDTPYKDHGIGNTLESLLLFIKNGDRLKRPENCSTDMYQLMLQCWNDDPKLRPNFNELVHKF
||  ||..||   .|    | |  . | | |. .|.||| ..| .| |||   |. || | .||  .
EIMTYGGQPY--PHIP-SVEELYKYLKEGHRMEKPHNCSQEIYHMMCQCWHFKPCQRPTFKQLVEYL
Kinase AqueK461.AA VEGFR 257-421 45 1.1e-70 241.15 In-house 170-332 (332) Show / Hide 
Range on Protein: 257-421
Range on HMM: 170-332/332
Sequence Identity: 45% (76 aa)

LTEKDIFNFSLQISRGMEHLQSQKCIHRDLAARNVLIAEGQILKIADFGLAKE-LSSK-DYYRRLSSGKLPARWMAVESLDDRQTHSHQSDIWSFGVVLW
|| .|  ..|.|. |||| | |.|||||||||||.|..|  ..|| |||||.  . .  || |. . |.|| .||| ||. |.   . .||.||.||.||
LTMEDLICYSFQVARGMEFLASRKCIHRDLAARNILLCENNVVKICDFGLARHGIYKDPDYVRKGDQGRLPIKWMAPESIFDK-VYTTYSDVWSYGVFLW

EICSYGDTPYKDHGIG-NTLESLLLFIKNGDRLKRPENCSTDMYQLMLQCWNDDPKLRPNFNELVHKF
|| | |  ||   |.  .  | .  ..|.| |...|. |   .|. ||.||  .|. || | |||...
EIFSLGGSPY--PGVQID--EEFCNRLKDGYRMRAPDYCTPEIYHIMLDCWHKEPEERPHFSELVEHL
Kinase AqueK461.AA UTK 265-421 34 1.5e-67 230.12 In-house 123-296 (296) Show / Hide 
Range on Protein: 265-421
Range on HMM: 123-296/296
Sequence Identity: 34% (61 aa)

FSLQISRGMEHLQSQKCIHRDLAARNVLIAEG-------QILKIADFG---LAKELS---------SKDYYRRLSSGKLPARWMAVESLDDRQTHSHQSD
....|.|||..| |....||||||||.|...        .. ||||||   ......         . .||.. . ...| |||| |.|... .....||
MAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQDRWPIRWMAPEALTHHTRFTTKSD

IWSFGVVLWEICSYGDTPYKDHGIGNTLESLLLFIKNGD--RLKRPENCSTDMYQLMLQCWNDDPKLRPNFNELVHKF
.||||||.|||...| .||...    . . ..... ||.  |...|. |. ..|.||..||. ||  ||.| .|| ..
VWSFGVVCWEIWTWGRLPYPGM----SNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDFEDLVQQM
Kinase AqueK461.AA Ret 260-423 47 1.3e-59 202.31 In-house 135-293 (293) Show / Hide 
Range on Protein: 260-423
Range on HMM: 135-293/293
Sequence Identity: 47% (78 aa)

KDIFNFSLQISRGMEHLQSQKCIHRDLAARNVLIAEGQILKIADFGLAKELSSKDYYRRLSSGKLPARWMAVESLDDRQTHSHQSDIWSFGVVLWEICSY
|.|  |  ||..||  | . | .||||||||||.||| |.|| ||||       | | . | ...|  |||.||| |      .||.||||| .|||   
KMIISFAWQICKGMHYLSEMKLVHRDLAARNVLVAEGRICKISDFGLTRDVYEDDSYVKRSKDRIPVKWMAIESLYD-HVYTTKSDVWSFGVLCWEIVTM

GDTPYKDHGIGNTLESLLLFIKNGDRLKRPENCSTDMYQLMLQCWNDDPKLRPNFNELVHKFDK
|  ||   ||  . | |    | | |  ||||||  || .|.||| . |  || |  .   | |
GANPY--PGI--PPERLWQLLKTGYRMDRPENCSEEMYRIMRQCWKQEPDKRPVFKFISKDFEK
Kinase AqueK461.AA Fer 242-422 31 2e-59 201.02 In-house 88-283 (283) Show / Hide 
Range on Protein: 242-422
Range on HMM: 88-283/283
Sequence Identity: 31% (63 aa)

IEMIDA---DTHMINHPL--LTEKDIFNFSLQISRGMEHLQSQKCIHRDLAARNVLIAEGQILK---IADFGLAKELS--SKDYYRRLSSGKLPARWMAV
.|...    |...   .   ...........|...|||.| |..|||||.||||.|. .... |   |.|||.....|   .||. .  . |.| ||.| 
MEFCNGGSLDSYLKKNKNKTVSDNEKIRMCYQAACGMEYLHSKNCIHRDIAARNCLYHKDKVKKKCKISDFGMSRQCSDYGYDYKMKEKACKVPIRWLAP

ESLDDRQTHSHQSDIWSFGVVLWEICSYGDTPYKD--HG--IGNTLESLLLF-IKNGDRLKRPENCSTDMYQLML-QCWNDDPKLRPNFNELVHKFD
|.....   |. .|.|||||..|||.. |..|| .  ||   .|. ...    ||.| ... |... ....|.|. |||. ||. ||...|...|. 
ETWQTGI-YSPKTDVWSFGVMCWEIFTNGAEPYPGQPHGMKMTNVKKQARKWIIKKGYMMPMPNHMPPEIMQIMMKQCWQKDPEDRPTMKEICQKLK
Kinase AqueK461.AA InsR 268-423 43 1.4e-52 174.91 In-house 127-278 (278) Show / Hide 
Range on Protein: 268-423
Range on HMM: 127-278/278
Sequence Identity: 43% (68 aa)

QISRGMEHLQSQKCIHRDLAARNVLIAEGQILKIADFGLAKELSSKDYYRRLSSGKLPARWMAVESLDDRQTHSHQSDIWSFGVVLWEICSYGDTPYKDH
.|  ||  | . | .|||||.|| ....    ||.|||..  .   ||||.   |.|| |||| ||| |    .| ||.|||||||||. . |  ||   
EICDGMAYLAAKKFVHRDLACRNCMVNHDFTVKIGDFGMTRDIYEHDYYRKGGKGMLPVRWMAPESLKDGVFTTH-SDVWSFGVVLWEMVTLGEQPYQ--

GIGNTLESLLLFI-KNGDRLKRPENCSTDMYQLMLQCWNDDPKLRPNFNELVHKFDK
|  |  |  | .| ..|  |..||||.  ...|| .||   ||.|| | ...|    
GLSN--EQVLKYIGMDGNVLRPPENCPEYWQELMMMCWQYQPKMRPTFLDIIHYLCD
Kinase AqueK461.AA Src 265-421 40 3.6e-52 175.52 In-house 102-255 (255) Show / Hide 
Range on Protein: 265-421
Range on HMM: 102-255/255
Sequence Identity: 40% (65 aa)

FSLQISRGMEHLQSQKCIHRDLAARNVLIAEGQILKIADFGLAKELSS--KDYYRRLSSGKLPARWMAVESLDDRQTHSHQSDIWSFGVVLWEICSYGDT
.. |...||. | |.. |||||||||||. |. . |.||||||. |    .| |   .  |.| .|.| | . .... .  || ||||. |.|| .|| .
MAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLAR-LIKEDDDEYCARHGAKFPIKWTAPEAI-NYGRFTIKSDVWSFGILLTEIVTYGRV

PYKDHGIGNTLESLLLFIKNGDRLKRPENCSTDMYQ-LMLQCWNDDPKLRPNFNELVHKF
||.    | | .  |  ...| |. .|.||   .|. .|||||. ||. || |  | ...
PYP----GMTNHEVLQQVERGYRMPCPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL
Kinase AqueK461.AA PDGFR 226-421 37 4e-49 155.65 In-house 163-358 (358) Show / Hide 
Range on Protein: 226-421
Range on HMM: 163-358/358
Sequence Identity: 37% (75 aa)

VDTQMIHVDTQMSNTDIEMIDADTH--MI--NHPLLTEKDIFNFSLQISRGMEHLQSQKCIHRDLAARNVLIAEGQILKIADFGLAKELSSKDYYRRLSS
||.|    .   ||  ...|. |    ..  . . || .|   || |. .||| | |  |.||||||||||...| . || |||||    .   |    .
VDMQRNNYMSPHSNYEDSYIEQDVKNELMEDDSNVLTYWDLLCFSYQVAKGMEFLASKNCVHRDLAARNVLLCHGKVVKICDFGLARDIMNDSNYVVKGN

GKLPARWMAVESLDDRQTHSHQSDIWSFGVVLWEICSYGDTPYKDHGIGNTLESLLLFIKNGDRLKRPENCSTDMYQLMLQCWNDDPKLRPNFNELVHKF
  ||  ||| ||. |      |||.||.|. |||| | | .||    . ..   .   ||.| | ..|.  . ..|. | .||. ||. || | .|.   
ARLPVKWMAPESIFD-CVYTTQSDVWSYGILLWEIFSLGGNPYPGMPVDSKFYKM---IKEGYRMAQPFHAPEEIYEIMQKCWDFDPEKRPTFQQLCQFL
Kinase AqueK461.AA TK-Unique 36-141 42 1e-34 117.15 In-house 1-107 (294) Show / Hide 
Range on Protein: 36-141
Range on HMM: 1-107/294
Sequence Identity: 42% (45 aa)

LHFQNTIGEGQFGQVWKAQAVGIVPEDPSLNIVAVKTLKGDADFIDKEELLAELEIMKNLYPHPNILNLLGYCTVGG-PCYIIMEFAMYGNLRDFLRSLK
| ....||||.|||||.....||  ..   ..||||.|| .|.. || ..| |...||.| .||||...||.||  . | .||||....|||...||. .
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR

NVHSSSQ
 .....|
PAMRQHQ
Kinase AqueK461.AA TK 36-132 25 2.9e-34 111.68 In-house 1-152 (486) Show / Hide 
Range on Protein: 36-132
Range on HMM: 1-152/486
Sequence Identity: 25% (39 aa)

LHFQNTIGEGQFG---QVWKAQAVGIVP-------------------EDPSLNIVAVKTLKGDADFIDKEELL----------------AELEIMKN-LY
... ...||||||   .|.|... |. |                   ..     ||||.|| ...  ..|...                .|...|.. |.
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

PHPNILNLLGYCTVG------------GPCYIIMEFAMYGN----LRDFLRS
 ||||..|.|.|| |            .|..|.||.. .|.    |||.||.
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRK
Kinase AqueK461.AA FGFR 36-132 47 3.6e-34 113.81 In-house 1-98 (293) Show / Hide 
Range on Protein: 36-132
Range on HMM: 1-98/293
Sequence Identity: 47% (47 aa)

LHFQNTIGEGQFGQVWKAQAVGIVPE-DPSLNIVAVKTLKGDADFIDKEELLAELEIMKNLYPHPNILNLLGYCTVGGPCYIIMEFAMYGNLRDFLRS
|    ..||| |||||.| |.||...      .|||| || ..   |   |  |.|.||    |.||.|||| || .|| |.| |..  ||||||||.
LTLGKMLGEGCFGQVWMAEAKGIDCDRPEKEITVAVKMLKMNHTDKDLSDLVSEMEMMKMIGKHKNIINLLGCCTQEGPLYVIVEYCHHGNLRDFLRA
Kinase AqueK461.AA Pkinase 245-421 23 2.8e-31 111.7 Pfam 89-293 (293) Show / Hide 
Range on Protein: 245-421
Range on HMM: 89-293/293
Sequence Identity: 23% (50 aa)

IDADTHMI--NHPLL--TEKDIFNFSLQISRGMEHLQSQKCIHRDLAARNVLIA-EGQI---LKIADFGLAKELSSKDYYRRLSSGKLPARWMAVESLDD
.|  ...   .|  .  .|... .. .|| ||.|.. |...|||||   |.||  .|.|   .||.|||||| ..    .. ...     ..|| | . .
MDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEVIRG

RQTHSHQSDIWSFGVVLWEICSYGDTPYKDH----GIGNTLESLLLFIKNGDRLKRPENCS-------------------TDMYQLMLQCWNDDPKLRPN
.| ... .|.||.|..|.| .. | .|...|    .  . .. . .  .   .  .|. ||                    .. ...  |.. ||| ||.
GQYYGPKVDMWSCGCILYEMLC-GRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT

FNELVHK--F
. ....   |
AEQILQHPWF
Kinase AqueK461.AA PDGFR 36-132 47 3.6e-31 97.04 In-house 1-96 (358) Show / Hide 
Range on Protein: 36-132
Range on HMM: 1-96/358
Sequence Identity: 47% (46 aa)

LHFQNTIGEGQFGQVWKAQAVGIVPEDPSLNIVAVKTLKGDADFIDKEELLAELEIMKNLYPHPNILNLLGYCTVGGPCYIIMEFAMYGNLRDFLRS
| |  | | | ||.|  | | |.  .....  |||| ||  |.   || |  || ||  | .| || |||| ||.||| ||| |.  || | ..|..
LQFGKTLGSGAFGKVVEATAYGLSKSQAVMK-VAVKMLKPTAHSSEKEALMSELKIMSHLGQHMNIVNLLGACTHGGPIYIITEYCCYGDLLNYLHR
Kinase AqueK461.AA VEGFR 36-132 37 8.7e-26 92.0 In-house 1-99 (332) Show / Hide 
Range on Protein: 36-132
Range on HMM: 1-99/332
Sequence Identity: 37% (37 aa)

LHFQNTIGEGQFGQVWKAQAVGIVPEDPSLNIVAVKTLKGDADFIDKEELLAELEIMKNLYPHPNILNLLGYCTV---GGPCYIIMEFAMYGNLRDFLRS
|.    .|.| |||| .|.|.||  . .   .|||| ||  |.   . .|..||.... .  | |  |.|| ||    .||  .|.|.  .||| ..||.
LKLGKMLGRGAFGQVHEASAFGIRKMETC-TTVAVKMLKEGATASEHRALMSELKMLIHIGHHLNVVNFLGCCTKNIQKGPLMVIVEYCCFGNLSNYLRT
Kinase AqueK461.AA Src 36-132 33 1.1e-22 73.83 In-house 1-88 (255) Show / Hide 
Range on Protein: 36-132
Range on HMM: 1-88/255
Sequence Identity: 33% (33 aa)

LHFQNTIGEGQFGQVWKAQAVGIVPEDPSLNIVAVKTLKGDADFIDKEELLAELEIMKNLYPHPNILNLLGYCTVGGPCYIIMEFAMYGNLRDFLR-S
...   .|.|||| ||..   | ..       ||||||| .    . | .|.| .|||.|  |.....|.  |. . | ||. |.   |.| |.|. .
IKLCRKLGQGQFGEVWMGYWNGNTK-------VAVKTLKPGT--MSPEAFLQEAQIMKKLR-HEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKKD
Kinase AqueK461.AA UTK 36-132 29 5.2e-22 72.1 In-house 1-103 (296) Show / Hide 
Range on Protein: 36-132
Range on HMM: 1-103/296
Sequence Identity: 29% (31 aa)

LHFQNTIGEGQFGQVWKAQAVGIVPEDPSLNIVAVKTLK-GDADFIDKE---ELLAELE---IMKNLYPHPNILNLLGYCTVGGPCYIIMEFAMYGNLRD
... ...|.|.||.| || .. . .  . . .||||... ....  ..|   ... |     .||... |||.|.|.|.|| ..| .|..|..  |.||.
VQLGRQLGQGAFGEVHKARFTQCSEHMYEM-DVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRS

FLRS
.||.
YLRR
Kinase AqueK461.AA InsR 36-133 35 5.4e-22 70.59 In-house 1-98 (278) Show / Hide 
Range on Protein: 36-133
Range on HMM: 1-98/278
Sequence Identity: 35% (35 aa)

LHFQNTIGEGQFGQVWKAQAVGIVPEDPSL-NIVAVKTLKGDADFIDKEELLAELEIMKNLYPHPNILNLLGYCTVGGPCYIIMEFAMYGNLRDFLRSL
.      |.| || |    | ||||. ..    .|.||.. .|   .. | | | ..||.   | .. .||| |. | | |..||.  ||.|...|||.
IVLIRECGQGSFGMVYEGIAKGIVPDEEWRFGRCAIKTVNENASMRERIEFLNEASVMKEFNCH-HVVRLLGVCSRGQPMYVVMEMMTYGDLKSYLRSR
Kinase AqueK461.AA Ret 36-131 41 9.4e-22 71.03 In-house 1-97 (293) Show / Hide 
Range on Protein: 36-131
Range on HMM: 1-97/293
Sequence Identity: 41% (41 aa)

LHFQNTIGEGQFGQVWKAQAVGIVPEDPSLNIVAVKTLKGD-ADFIDKEELLAELEIMKNLYPHPNILNLLGYCTVGG--PCYIIMEFAMYGNLRDFLR
| .  | ||| |||| ||||  |    |    |||| || . |       || |... | .  ||..  |.| |.  .  |  .| |.. || || |||
LQLDDTLGEGHFGQVVKAQAFHIRGH-PGYTTVAVKMLKRNTANSSEYHDLLSEFQLLKQVN-HPHVIKLYGACIQDDPFPTCLIVEYCKYGCLREFLR
Kinase AqueK461.AA S_TKc 36-425 14 3.6e-19 70.92 SMART 1-231 (231) Show / Hide 
Range on Protein: 36-425
Range on HMM: 1-231/231
Sequence Identity: 14% (60 aa)

LHFQNTIGEGQFGQVWKAQAVGIVPEDPSLNIVAVKTLKGDADFIDKEELLAELEIMKNLYPHPNILNLLGYCTVGGPCYIIMEFAMYGNLRDFLRSLKN
 .. ..||.| ||.|.|.. ..      .  |||.| .|                                                             
YEILRKIGKGAFGKVYKCRHKK------TGRIVAIKIIK-------------------------------------------------------------

VHSSSQAIFAPFQSSSNHPMALNEGQTVDPWSLYNNIPIHYNTVLKQHLINTDYYNQHNNGIEDTQLINADTQMINADTQIVNADTQMIDVDTQMIHVDT
                                                                        ..|    ||        .   ... |  
------------------------------------------------------------------------EHIRREIQILKK---HHPNIVKLYDVFQ

QMSNTDI----EMIDA-----DTHMINHPL------LTEKDIFNFSLQISRGMEHLQSQKCIHRDLAARNVLIAEGQILKIADFGLAKELSSKDYYRRLS
    ...    |..|       ... ...       ..| ..  .  || ...|.. |.. |||||   |.|. |   .||.|||||..|         .
D---DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---------T

SGKLPARWMAVESLDDRQTHSH-QSDIWSFGVVLWEICSYGDTPYKDHGIGNTLESLLLFIKNGDRLKRPENCSTDMYQLMLQCWNDDPKLRPNFNELVH
.      .|| | |     ...  .|.||.|..|.| .. | .|.       ... ..  |.           | .. ... .|.. ||. ||   |. .
TFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYEMLC-GYPPFP------QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQ

-----KFDKLL
     | .  .
DEWDIKCHPWF
Kinase AqueK461.AA Fer 36-131 30 1.6e-18 59.77 In-house 1-101 (283) Show / Hide 
Range on Protein: 36-131
Range on HMM: 1-101/283
Sequence Identity: 30% (31 aa)

LHFQNTIGEGQFGQVWKA-QAVGIVPEDPSLN----IVAVKTLKGD-ADFIDKEELLAELEIMKNLYPHPNILNLLGYCTVGGPCYIIMEFAMYGNLRDF
 .... .||| || |.|. . .     . ...     |.||..|.. |.   ..|...|  ||.| | |||.  . |.|.   | .|.|||.  |.|...
VTLGKKLGEGAFGEVYKGRR-TLKCKKGKWHVVNKVAVKVKKCKCEDATKEQIKEFMHEARIMRNNYDHPNVVKFYGVCVDEQPIMIVMEFCNGGSLDSY

LR
|.
LK
Kinase AqueK461.AA Pkinase 36-131 31 3e-17 62.07 Pfam 1-96 (293) Show / Hide 
Range on Protein: 36-131
Range on HMM: 1-96/293
Sequence Identity: 31% (32 aa)

LHFQNTIGEGQFGQVWKAQAVGIVPEDPSLNIVAVKTLKGDADFIDKEELLA---ELEIMKNLYPHPNILNLLGYCTVGGPCYIIMEFAMYG----NLRD
.|.  .||.| ||.|.|.. .|         |||||..| . .  .|.. ..   |..|||.|  ||||. |..... .. .|..||... |     | |
YHIGRKIGSGSFGCVYKCHHKGTGK------IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFD

FLR
...
YIS