Gene AqueK469 (A.queenslandica)

AqueK469

Species: A.queenslandica
Alias: AqueK469
External Links:
Annotation:

Classification

Group: TK
Family: TMR

Sequence

Name Sequence Type Origin Length Description Download
AqueK469.AA Protein None 755 None Fasta, JSON
AqueK469.kin_dom Protein Kinase Domain None 267 None Fasta, JSON

Protein domain

Protein domains of AqueK469.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase AqueK469.AA Pkinase_Tyr 640-745 51 3.8e-55 187.4 Pfam 120-227 (270) Show / Hide 
Range on Protein: 640-745
Range on HMM: 120-227/270
Sequence Identity: 51% (56 aa)

IANAMAFLESNKYVHRDIAARNCLVGPNLEVKVADFGMARMVQEKEYY-KIAGRAVLPVRWMAPESLIYGYFTSSSDVWSYGVLLWEIATYGTVP-LESS
||..|..|||....|||.|||||||. |. ||..|||.|| .....|| . .| . ||..|||||.. || ||. |||||.|||.||| |||  |  .  
IAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGM

SVQEIVEM
| .|..|.
SNEEVYEY
Kinase AqueK469.AA TK 640-748 32 4.1e-53 175.99 In-house 243-419 (486) Show / Hide 
Range on Protein: 640-748
Range on HMM: 243-419/486
Sequence Identity: 32% (57 aa)

IANAMAFLESN------KYVHRDIAARNCLVGPNLE-----------VKVADFG--------MARMVQEKEYYKIAG-----------------------
||..|..|.|.      ..||||.|||||||| |.            .|.||||        .|| ......|  ..                       
IACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQ

-RAVLPVRWMAPESLI---------YGYFTSSSDVWSYGVLLWEIATYG-TVPLESSSV---------QEIVEMAQN
 .. ||.||||||.|          || ||. |||||.|||.||| ||| . . .  |          ||..|. ..
SGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMSNQDVWKDGDNQEVMEYLRR
Kinase AqueK469.AA InsR 640-733 55 8.3e-52 172.25 In-house 128-221 (278) Show / Hide 
Range on Protein: 640-733
Range on HMM: 128-221/278
Sequence Identity: 55% (52 aa)

IANAMAFLESNKYVHRDIAARNCLVGPNLEVKVADFGMARMVQEKEYYKIAGRAVLPVRWMAPESLIYGYFTSSSDVWSYGVLLWEIATYGTVP
|.  ||.|...|.|||| |.|||.|   . ||..||||.| . |  ||.  |.  |||||||||||  | ||..|||||.||.|||..| |  |
ICDGMAYLAAKKFVHRDLACRNCMVNHDFTVKIGDFGMTRDIYEHDYYRKGGKGMLPVRWMAPESLKDGVFTTHSDVWSFGVVLWEMVTLGEQP
Kinase AqueK469.AA UTK 640-733 43 6.1e-48 162.09 In-house 127-240 (296) Show / Hide 
Range on Protein: 640-733
Range on HMM: 127-240/296
Sequence Identity: 43% (50 aa)

IANAMAFLESNKYVHRDIAARNCLVGPN-------LEVKVADFG---MARMVQ---------EKEYYKIAGRAVLPVRWMAPESLIYG-YFTSSSDVWSY
||..|..|.| ..||||.|||||||. .       . .|.||||   |.|.|.         | .||. ...  .|.||||||.|...  ||..|||||.
IARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQDRWPIRWMAPEALTHHTRFTTKSDVWSF

GVLLWEIATYGTVP
||..||| |.| .|
GVVCWEIWTWGRLP
Kinase AqueK469.AA Trk 640-744 50 5.8e-46 153.75 In-house 126-231 (275) Show / Hide 
Range on Protein: 640-744
Range on HMM: 126-231/275
Sequence Identity: 50% (54 aa)

IANAMAFLESNKYVHRDIAARNCLVGPNLEVKVADFGMARMVQE-KEYYKIAGRAVLPVRWMAPESLIYGYFTSSSDVWSYGVLLWEIATYGTVPLESSS
||  | .. |  .||||.|.|||||| || ||..|||| | | .  .||.. ..  ||.||| ||| .|  ||  |||||.|| .||. |||  |    |
IASGMVYMASQHFVHRDMATRNCLVGQNLIVKIGDFGMSRDVYSHTDYYRVGHHTMLPIRWMPPESIMYRKFTYESDVWSFGVVMWECFTYGKQPWYQLS

VQEIVE
 .|..|
NHEVIE
Kinase AqueK469.AA Src 640-733 56 2.9e-45 151.7 In-house 106-200 (255) Show / Hide 
Range on Protein: 640-733
Range on HMM: 106-200/255
Sequence Identity: 56% (54 aa)

IANAMAFLESNKYVHRDIAARNCLVGPNLEVKVADFGMARMVQ--EKEYYKIAGRAVLPVRWMAPESLIYGYFTSSSDVWSYGVLLWEIATYGTVP
.|. ||.|||..|.||| |||| ||| |. .|||||| ||...  . ||    | | .|..|.||| . || ||  |||||.|.||.|| ||| ||
VAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLARLIKEDDDEYCARHG-AKFPIKWTAPEAINYGRFTIKSDVWSFGILLTEIVTYGRVP
Kinase AqueK469.AA Src-Unclassified 640-733 53 3.8e-45 152.72 In-house 128-227 (284) Show / Hide 
Range on Protein: 640-733
Range on HMM: 128-227/284
Sequence Identity: 53% (54 aa)

IANAMAFLESNKYVHRDIAARNCLVGPNL-----EVKVADFGMA--RMVQEKEYYKIAGRAVLPVRWMAPESLIYGYFTSSSDVWSYGVLLWEIATYGTV
.|. |  |||.|||||| |||| |.| |      .|||.||| |  . .|. .|    | | .|. |||||  ||| |.  |||||||.|||||.|.| .
VASGMMYLESKKYVHRDLAARNVLIGHNNSNGVPVVKVCDFGLARKKLMQDDNYCMRTG-AMFPWKWMAPECFIYGNFSIKSDVWSYGILLWEIMTKGQT

P
|
P
Kinase AqueK469.AA TK-Unique 640-745 44 6.9e-45 152.72 In-house 140-251 (294) Show / Hide 
Range on Protein: 640-745
Range on HMM: 140-251/294
Sequence Identity: 44% (50 aa)

IANAMAFLES--NKYVHRDIAARNCLVGPNLEVKVADFGMARMVQ-EKEYYKIAGRAVLPVRWMAPESLI--YGYF-TSSSDVWSYGVLLWEIATYGTVP
||..|..|.|   | ||||..|||.|.. ....|..|||||| |. ...| .. ..  .|.||||||||   .| . |. |||||.|||.|||.|.|  |
IACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMCSQGRIPIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACP

LESSSVQEIVEM
  . .  .|.|.
YPGMPWKDIMEC
Kinase AqueK469.AA DDR 640-728 46 9.5e-45 153.95 In-house 143-238 (306) Show / Hide 
Range on Protein: 640-728
Range on HMM: 143-238/306
Sequence Identity: 46% (45 aa)

IANAMAFLESNKYVHRDIAARNCLVGPNLEVKVADFG--MARMVQEKEYYKIAG-----RAVLPVRWMAPESLIYGYFTSSSDVWSYGVLLWEIAT
|| .|..|||   ||||.|.||||||... .|..|||  |.|     .||.. |     |...|.||||.||.. | ||. ||||. || .||...
IASGMKYLESMNFVHRDLATRNCLVGKEYHIKICDFGTVMSRNLYSQDYYRVEGFTGRQRHHMPIRWMAWESILLGKFTTKSDVWAFGVTMWEMFM
Kinase AqueK469.AA Ror 640-745 49 6.9e-44 152.13 In-house 128-233 (308) Show / Hide 
Range on Protein: 640-745
Range on HMM: 128-233/308
Sequence Identity: 49% (52 aa)

IANAMAFLESNKYVHRDIAARNCLVGPNLEVKVADFGMARMVQEKEYYKIAGRAVLPVRWMAPESLIYGYFTSSSDVWSYGVLLWEIATYGTVPLESSSV
||  | .| |  .|||| ||||||||  . ||..||| .| .    ||.. .....|.|||.||.  || |.. ||.||.|| ||||  ||  | .  | 
IAAGMEYLSSHHFVHRDLAARNCLVGEHHHVKISDFGLMRDIYSSDYYRMQHKSWMPIRWMSPEAIMYGKFSEDSDIWSFGVVLWEIWSYGMQPYYGYSN

QEIVEM
||..||
QEVIEM
Kinase AqueK469.AA CTKB 640-744 48 1.2e-42 148.04 In-house 118-223 (269) Show / Hide 
Range on Protein: 640-744
Range on HMM: 118-223/269
Sequence Identity: 48% (51 aa)

IANAMAFLESNKYVHRDIAARNCLVGPNLEVKVADFGMARMVQEKEYYKIAGRAVLPVRWMAPESLIYGYFTSSSDVWSYGVLLWEIATYGTVPLES-SS
.|. ||.. | . |||| |||||||  | .| . |||. | |  .||||  . . ||.|||.|||.  | .|. |||||||...||| |..  |     .
VADGMAYIASKRIVHRDLAARNCLVHQNWRVCIGDFGISRDVYMREYYKMQASNPLPIRWMSPESINDGVYTTQSDVWSYGIVIWEIMTFAKMPYPEYET

VQEIVE
 .|.||
NMEVVE
TyrKc AqueK469.AA TyrKc 585-755 22 6.9e-24 86.59 SMART 1-280 (280) Show / Hide 
Range on Protein: 585-755
Range on HMM: 1-280/280
Sequence Identity: 22% (68 aa)

VTFYE--------------YNKERADDNIAGYKGKLPVAVKTLTSIEEEDVQKFLEEIELMKKF--SNPHI-----------------------------
.|. .              ..              ..||||.| .     .. |..|...|.|.  ..|.|                             
ITLGKKLGEGAFGEVYKGTWK--------------IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPH

-------------------------IANAMAFLESNKYVHRDIAARNCLVGPNLEVKVADFGMARMVQEK-------EYYKI----AGRAVLPVRWMAPE
                         ||. |..|.|....|||.|||||||| |. ||..|||..| . ..       .||.      |...||.||||||
GDLKDYLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPE

SLIYGYFTSSSDVWSYGVLLWEIATYGTVPLES-----SSVQEIVEMAQNK----------------------------------------TLYHTX
.. || ||. |||||.||..||| |||  | .       | ||..|  ..                                         ....  
CINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase AqueK469.AA Pkinase 640-745 22 7.5e-13 46.53 Pfam 117-229 (293) Show / Hide 
Range on Protein: 640-745
Range on HMM: 117-229/293
Sequence Identity: 22% (26 aa)

IANAMAFLESNKYVHRDIAARNCLVGPNLEV----KVADFGMARMVQEKEYYKIAGRAVLPVRWMAPESLI-YGYFTSSSDVWSYGVLLWEIATYGTVPL
|. ..... |.. .|||.   |.|.  | ..    |..||| |. ..    .  .   .   ..|||| .  . | ....|.||.|..|.| .. |  | 
ILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLC-GRPPF

ESS------SVQEIVEM
 ..      . ......
PGHCWHDNHDQMQMICR
S_TKc AqueK469.AA S_TKc 572-751 15 4.4e-08 -58.45 SMART 1-231 (231) Show / Hide 
Range on Protein: 572-751
Range on HMM: 1-231/231
Sequence Identity: 15% (42 aa)

FTLKPKFGVMSPSVTFYEYNKERADDNIAGYKGKLPVAVKTLTSIEEEDVQKFLEEIELMKKFSNPHI--------------------------------
...  | |  . .. .  ..|.           .  ||.| .        .... ||...||   |.|                                
YEILRKIGKGAFGKVYKCRHKK----------TGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKK

--------------------IANAMAFLESNKYVHRDIAARNCLVGPNLEVKVADFGMARMVQEKEYYKIAGRAVLPVRWMAPESLIYGYFTS-SSDVWS
                    |..|.... |.. .|||.   | |.    ..|..|||.|| .            .    .|||| |    ..  ..|.||
RGRHGLRFPFPEHARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL---GYGKCKCDWWS

YGVLLWEIATYGTVPLESSSVQE---------------------------IVEMAQ-------NKTL
 |..|.| .. |  | .   .|.                           . |  |          .
CGCILYEMLC-GYPPFP--QMQMMFKKIGSPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK469.AA Pkinase_Tyr 601-639 32 8.9e-08 26.96 Pfam 24-66 (270) Show / Hide 
Range on Protein: 601-639
Range on HMM: 24-66/270
Sequence Identity: 32% (14 aa)

GYKGKLPVAVKTL--TSIEEE-DVQKFLEEIELMKKF-SNPHI
. ..|.|||||.|  .. .|.   ..|..|...||.. ..|.|
PDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNI
Kinase AqueK469.AA Src 602-639 34 3e-06 17.05 In-house 20-56 (255) Show / Hide 
Range on Protein: 602-639
Range on HMM: 20-56/255
Sequence Identity: 34% (13 aa)

YKGKLPVAVKTLTSIEEEDVQKFLEEIELMKKFSNPHI
..|. .|||||| .    ... ||.|...|||.. ...
WNGNTKVAVKTLKPGT-MSPEAFLQEAQIMKKLRHEKL
Kinase AqueK469.AA TK 603-639 32 0.000188 10.0 In-house 50-105 (486) Show / Hide 
Range on Protein: 603-639
Range on HMM: 50-105/486
Sequence Identity: 32% (18 aa)

KGKLPVAVKTLT---SIEEEDVQK-----------FLEEIELMKKFS-----NPHI
.|| |||||.|.   . ..|. .            |||| | ||...      |.|
GGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLGHHPNI
Kinase AqueK469.AA TK-Unique 608-633 48 0.100513 1.87 In-house 33-59 (294) Show / Hide 
Range on Protein: 608-633
Range on HMM: 33-59/294
Sequence Identity: 48% (13 aa)

VAVKTLT-SIEEEDVQKFLEEIELMKK
||||.|  .  ..|.|.|| ||..||.
VAVKMLKDNATDTDKQDFLKEIQMMKE
Kinase AqueK469.AA Trk 598-639 35 0.212928 0.4 In-house 22-63 (275) Show / Hide 
Range on Protein: 598-639
Range on HMM: 22-63/275
Sequence Identity: 35% (15 aa)

NIAGYKGKLPVAVKTLTSIEEEDVQKFLEEIELMKKFSNPHI
|. . ..|. ||||||    |.  . |  | ||. .   .||
NLCPEQDKMMVAVKTLKDASENARKDFQREAELLTNLQHQHI