Gene AqueK470 (A.queenslandica)

AqueK470

Species: A.queenslandica
Alias: AqueK470
External Links:
Annotation:

Classification

Group: TK
Family: TMR

Sequence

Name Sequence Type Origin Length Description Download
AqueK470.AA Protein None 1217 None Fasta, JSON
AqueK470.kin_dom Protein Kinase Domain None 280 None Fasta, JSON

Protein domain

Protein domains of AqueK470.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
IGc2 AqueK470.AA IGc2 232-296 30 6e-06 27.11 SMART 1-56 (56) Show / Hide 
Range on Protein: 232-296
Range on HMM: 1-56/56
Sequence Identity: 30% (20 aa)

DEMTSETVKCTARGFPTPLVRWIKVVSNGVGITQRSGYGSSTLILNDATSDMSGEYYCLAQNVQV
 | .| | .| |.|.|.| ..|.|    |  .      ...|| . ..| . ||.| |.|.|   
HEGQSVTLTCPATGNPDPNIHWYK----GQPLP-----WNWTLTIKNVTPEDSGYYTCYARNPWG
IG AqueK470.AA IG 226-316 14 0.000162 22.25 SMART 1-58 (58) Show / Hide 
Range on Protein: 226-316
Range on HMM: 1-58/58
Sequence Identity: 14% (14 aa)

LSNVVMDEMTSETVKCTARGFPTPLVRWIKVVSNGVGITQRSGYGSSTLILNDATSDMS---GEYYCLAQNVQVNPPEGKRLVDKA-RSVFVTVR
 . |.  |  . | .| .       ..|                    |.. ... . |   |.||| |.            ....  .. .||.
PP-VTVKEGETVTLTC-VS-----QIWWY-------------------LTI-NVQPEDSQQHGTYYCQAT----------HGQYWSIQGTTLTVQ
I-set AqueK470.AA I-set 220-293 26 0.000467 16.28 Pfam 1-79 (92) Show / Hide 
Range on Protein: 220-293
Range on HMM: 1-79/92
Sequence Identity: 26% (22 aa)

PAIDQTLSNVVMDEMTSETVKCTARGFPTPLVRWIKVVSNGVGITQ--------RSGYGSSTLILNDATSDMSGEYYCLAQN
| ..|....|.  |  . . .|...| |.| | | |    |  ...        ..| | .||.  ....| .|.| | |.|
PKFTQKPKDVEVQEGETARFECQVTGDPPPQVSWFKD---GQPLRPDSDRHQMTYDGDGTYTLTISNVQPDDEGKYTCVATN
KR AqueK470.AA KR 472-555 46 3.8e-28 100.76 SMART 1-90 (90) Show / Hide 
Range on Protein: 472-555
Range on HMM: 1-90/90
Sequence Identity: 46% (43 aa)

GSCVRG--KGIGYTGRQDRTRSNHPCQLWVLQTPHRHPMLPSVYAT------ELHNAGQSCRNPGGLGERPWCYTSDPNVR-WEYCDIPSCDT
. |..|  .| .| |  ..|.| |||| |  |.|| | ..|. .          ||    ||||.|  |.||||| ||||| |||||||.|. 
RDCYWGDDNGESYRGTVNTTWSGHPCQRWDSQYPHLHWFYPEWFPCAGQLGLLEHNY---CRNPDGDSEGPWCYTMDPNVRDWEYCDIPQCED
Kringle AqueK470.AA Kringle 474-553 50 3.9e-24 85.11 Pfam 1-85 (85) Show / Hide 
Range on Protein: 474-553
Range on HMM: 1-85/85
Sequence Identity: 50% (45 aa)

CVRGKGIGYTGRQDRTRSNHPCQLWVLQTPHRHPM-LPSVYATE---L--HNAGQSCRNPGGLGER-PWCYT-SDPNVRWEYC-DIPSC
|..|.| .| |  ..|.| .||| |  |||||||.  |. ..     .  ||    |||| |  || |||||  || |||||| |||.|
CYHGNGENYRGTWSTTESGRPCQRWDSQTPHRHPFYTPENFPCKGLGEGKHNY---CRNPDGD-ERGPWCYTQTDPRVRWEYCSDIPRC
KR AqueK470.AA KR 699-776 34 2.2e-20 74.99 SMART 1-90 (90) Show / Hide 
Range on Protein: 699-776
Range on HMM: 1-90/90
Sequence Identity: 34% (31 aa)

YTCYVN--KGIDYLGNVSITESGATCHDWKS---EDHPISTMYHPTLA----NAQNHCRNPGGVLRRPWCYT-GSNS--WEYCRVRYCDN
..||..  .| .| |.|. |.||..|  | |    .|  . . .| .     . .|.||||.|  ..||||| ..|   ||||.. .|..
RDCYWGDDNGESYRGTVNTTWSGHPCQRWDSQYPHLHWFYPEWFPCAGQLGLLEHNYCRNPDGDSEGPWCYTMDPNVRDWEYCDIPQCED
Kringle AqueK470.AA Kringle 701-774 37 8.2e-18 63.48 Pfam 1-85 (85) Show / Hide 
Range on Protein: 701-774
Range on HMM: 1-85/85
Sequence Identity: 37% (32 aa)

CYVNKGIDYLGNVSITESGATCHDWKSEDHPIS-TMYHPTLANAQ-------NHCRNPGGVLRRPWCYT---GSNSWEYCR-VRYC
|| ..|  | |..| ||||..|  | .  .|.   .|.|.  ...       | |||| |  | |||||    . .||||. ...|
CYHGNGENYRGTWSTTESGRPCQRW-DSQTPHRHPFYTPENFPCKGLGEGKHNYCRNPDGDERGPWCYTQTDPRVRWEYCSDIPRC
Pkinase_Tyr AqueK470.AA Pkinase_Tyr 892-1175 45 4e-136 461.64 Pfam 1-270 (270) Show / Hide 
Range on Protein: 892-1175
Range on HMM: 1-270/270
Sequence Identity: 45% (132 aa)

IQYAGQLGQGNFGIVFKGRAFGIASDDEEIEVAVKTLKEESSSEI--RSNFIEEAKLMFSF-DHPNILHIYGVCM-TEMP--YQMVFEYMDEGDLTQYLR
|.   .||.|.|| |.||...|   |...|.||||.||| ...|   |  |..|||.| .. .||||.  ||||.  . |  . .|.|||  |||  |||
ITFGKKLGEGAFGEVYKGTWKG-DPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

SKASSMQRRLLNPFDHRSRTESSYSNDPPALSKTQLLSICRQIASGMEYLASKNHVHRDLACRNCLINSDLKVKIGDFGMSRNLYSRDYY-RINGQAILP
..                       .|...|.  .||..|.|||.|||||.||| .|||||.||||......|||.|||..| .|. ||| |  | . ||
KHR----------------------EDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLP

VRWMSPESLVYGKFSIEGDVWSFGVVMWEVFSFALQP-YYGLSNEEVTEAI-RHGKVLHRPDDCPSEVYNVMKECWDMEAKSRPTFEELHTAL
..||.||.. ||||... |||||||.|||.|..  || |.|.||||| |.| ..|  . .|..|| |.|..||.||. ... ||||.|.|  |
IKWMAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
TyrKc AqueK470.AA TyrKc 892-1175 39 6.30000000001e-136 458.79 SMART 1-280 (280) Show / Hide 
Range on Protein: 892-1175
Range on HMM: 1-280/280
Sequence Identity: 39% (126 aa)

IQYAGQLGQGNFGIVFKGRAFGIASDDEEIEVAVKTLKEESSSEIRSNFIEEAKLMFSF--DHPNILHIYGVCMTE-------MPYQMVFEYMDEGDLTQ
|.   .|| |.||.|.||..         |.||||.|||..    |  |..||..| ..  .||||. .||||...        |. .|.|||. ||| .
ITLGKKLGEGAFGEVYKGTWK--------IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKD

YLRSKASSMQRRLLNPFDHRSRTESSYSNDPPALSKTQLLSICRQIASGMEYLASKNHVHRDLACRNCLINSDLKVKIGDFGMSRNLYSR-------DYY
|||..                            |.  .|||.| |||.|||||.||| .|||||.||||..... |||.|||.||..|.        |||
YLRKHRPK-------------------------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYY

RING--QAI--LPVRWMSPESLVYGKFSIEGDVWSFGVVMWEVFSFALQPYYG-----LSNEEVTEAIRHGKVLHRPDD--------CPSEVYNVMKECW
|  .  ..   ||.|||.||.. ||||... |||||||.|||.|..  |||.|     .||.|| | ...|. . .|..        ||.|.|..||.||
RKKEHKGGKTMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCW

DMEAKSRPTFEELHTAL
. ....||||.|.|  .
HEDPEDRPTFSEIHECF
Kinase AqueK470.AA TK 892-1175 26 2.2e-120 405.52 In-house 1-486 (486) Show / Hide 
Range on Protein: 892-1175
Range on HMM: 1-486/486
Sequence Identity: 26% (131 aa)

IQYAGQLGQGNFG---IVFKGRAFGIA--------------------SDDEEIEVAVKTLKEESSSEIRS----------------NFIEEAKLMFS--F
|..  .||.|.||    |.||...|.                     .......||||.|||..... .                 .. ||.|.| .  .
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

DHPNILHIYGVCMTE------------MPYQMVFEYMDEGD----LTQYLRSKASSMQRRLLNPFD---------------------HRSRTESSYSND-
.||||...||||. .             |. .| |||. ||    | .|||..   .|  . .| .                     |.|. .  .... 
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPC-PEEQD

---------PPALSKTQLLS-------------------ICRQIASGMEYLASK------NHVHRDLACRNCLINSDLK-----------VKIGDFGMS-
         ||.|. ..||.                   .|.|||.|||||.||      | ||||||.||||......           .||.|||.| 
YDDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-------RNLYSRDYYRING------------------------QAILPVRWMSPESLV---------YGKFSIEGDVWSFGVVMWEVFSFALQPYYG-L
       | .||.|.|.  .                        .. ||.|||.||.|          ||||... |||||||.|||.|... .|||| .
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

SN---------EEVTEAIRHG--------------KVLHRPDDCP--------------SEVYNVMKECWDMEAKSRPTFEELHTAL
||         .|| | .| |                . .|..||               |.| .|..||. ... ||||..|| .|
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase AqueK470.AA Musk 892-1175 43 3.2e-118 392.33 In-house 1-282 (282) Show / Hide 
Range on Protein: 892-1175
Range on HMM: 1-282/282
Sequence Identity: 43% (127 aa)

IQYAGQLGQGNFGIVFKGRAFGIASDDEEIEVAVKTLKEESSSEIRSNFIEEAKLMFSFDHPNILHIYGVCMTEMPYQMVFEYMDEGDLTQYLRSKASSM
| |   .|.| || ||  || |   ..||. |||| ||.. | ..   |  || .|  ||||||    |||    |  . |||| .|||  .|.|     
IIYVRDIGEGAFGRVFQARAPGLVPYEEETMVAVKMLKDDASKQMQMDFQREACMMAEFDHPNIVKLLGVCFVGRPMCLLFEYMAYGDLNEFLHSCS---

QRRLLNPFDHRSRTESSYS-------NDPPALSKTQLLSICRQIASGMEYLASKNHVHRDLACRNCLINSDLKVKIGDFGMSRNLYSRDYYRINGQAILP
      |.   ||| .. .         || |.   .| . .||| || ||  .  |||||| ||||||.   ||| |||.||. |..|||. ..    |
------PHRTCSRTHQDRGMRAQVSSPGPPQLKCYHQLCMAKQIACGMAYLSEMMFVHRDLATRNCLINEHMDVKIADFGLSRYIYHQDYYKGHENDHIP

VRWMSPESLVYGKFSIEGDVWSFGVVMWEVFSFALQPYYGLSNEEVTEAIRHGKVLHRPDDCPSEVYNVMKECWDMEAKSRPTFEELHTAL
.||| |||. | .|..| |||..||..||.||.|||||||.. |||   || | .|  |. || .||..|..||. .   || | ..|  .
IRWMPPESIWYNQFTYESDVWAYGVCLWEIFSYALQPYYGMTHEEVIYYIRQGNILSCPENCPQKVYQLMRRCWQKNPADRPFFCQIHHCI
Kinase AqueK470.AA Trk 892-1175 44 3.4e-116 392.34 In-house 1-275 (275) Show / Hide 
Range on Protein: 892-1175
Range on HMM: 1-275/275
Sequence Identity: 44% (128 aa)

IQYAGQLGQGNFGIVFKGRAFGIASDDEEIEVAVKTLKEESSSEIRSNFIEEAKLMFSFDHPNILHIYGVCMTEMPYQMVFEYMDEGDLTQYLRSKASSM
|   . || | || || .    .  ... . |||||||. |  . |  |  ||.|.   .|..|  .||||  . |  ||||||  ||| .|||...   
IVLKWELGEGAFGKVFLAECYNLCPEQDKMMVAVKTLKDASE-NARKDFQREAELLTNLQHQHIVKFYGVCTDHDPLLMVFEYMKHGDLNKYLRQHGPDA

QRRLLNPFDHRSRTESSYSNDPPALSKTQLLSICRQIASGMEYLASKNHVHRDLACRNCLINSDLKVKIGDFGMSRNLYS-RDYYRINGQAILPVRWMSP
.  . .. .. ....         |   |.| | .|||||| |.||   ||||.| ||||.  .| |||||||||| .||  ||||. ..  ||.||| |
MCYAQYQ-PRQAPGP---------LTIDQMLWIAKQIASGMVYMASQHFVHRDMATRNCLVGQNLIVKIGDFGMSRDVYSHTDYYRVGHHTMLPIRWMPP

ESLVYGKFSIEGDVWSFGVVMWEVFSFALQPYYGLSNEEVTEAIRHGKV-LHRPDDCPSEVYNVMKECWDMEAKSRPTFEELHTAL
|| .| ||..| |||||||||||.|..  ||.|.||| || | |  |.. | ||  || |||..|  || .| . | .  ..|...
ESIMYRKFTYESDVWSFGVVMWECFTYGKQPWYQLSNHEVIECIHQGRHRLERPRRCPQEVYDIMLGCWQREPQQRMNIKDIHDII
Kinase AqueK470.AA InsR 892-1177 42 8.20000000001e-115 387.1 In-house 1-278 (278) Show / Hide 
Range on Protein: 892-1177
Range on HMM: 1-278/278
Sequence Identity: 42% (123 aa)

IQYAGQLGQGNFGIVFKGRAFGIASDDEEI--EVAVKTLKEESSSEIRSNFIEEAKLMFSFDHPNILHIYGVCMTEMPYQMVFEYMDEGDLTQYLRSKAS
|    ..||| || |  | | || .| |..  ..|.||..|. |.. | .|  ||  |  |.. ..   .||| .  |   | | |. |||  ||||.  
IVLIRECGQGSFGMVYEGIAKGIVPDEEWRFGRCAIKTVNENASMRERIEFLNEASVMKEFNCHHVVRLLGVCSRGQPMYVVMEMMTYGDLKSYLRSRRP

SMQRRLLNPFDHRSRTESSYS--NDPPALSKTQLLSICRQIASGMEYLASKNHVHRDLACRNCLINSDLKVKIGDFGMSRNLYSRDYYRINGQAILPVRW
 ..             .  .    ..|.|.  |...   .|..|| |||.|. ||||||||||..| |. |||||||| | .|  ||||  |   |||||
EEEF-----------NNPGCNRNQHVPCLD--QMHQMAAEICDGMAYLAAKKFVHRDLACRNCMVNHDFTVKIGDFGMTRDIYEHDYYRKGGKGMLPVRW

MSPESLVYGKFSIEGDVWSFGVVMWEVFSFALQPYYGLSNEEVTEAI-RHGKVLHRPDDCPSEVYNVMKECWDMEAKSRPTFEELHTALCQ
|.||||  |.|.   ||||||||.||. ... ||| |||||.| . | . |.|| .|. ||  .. .|. ||    | |||| ..   ||.
MAPESLKDGVFTTHSDVWSFGVVLWEMVTLGEQPYQGLSNEQVLKYIGMDGNVLRPPENCPEYWQELMMMCWQYQPKMRPTFLDIIHYLCD
Kinase AqueK470.AA UTK 892-1175 35 2.9e-108 365.99 In-house 1-296 (296) Show / Hide 
Range on Protein: 892-1175
Range on HMM: 1-296/296
Sequence Identity: 35% (112 aa)

IQYAGQLGQGNFGIVFKGRAFGIASDDEEIEVAVKTLKEESSSEIRSN----FIEEAK---LMFSFD-HPNILHIYGVCMTEMPYQMVFEYMDEGDLTQY
.|   |||||.||.|.|.|.  ..   .|  ||||.........  .     |.|||.   .|  |. |||.|  .|||. |.|  .| ||| .||| .|
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSY

LRSKASSMQRRLLNPFDHRSRTESSYSNDPPALSKTQLLSICRQIASGMEYLASKNHVHRDLACRNCLINSD-------LKVKIGDFG---MSRNLY---
||. . .                     .| .|...|.|. ...||.||.||.|.. ||||||.||||....       ...||.|||   |||...   
LRRHRPTPP------------------ACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFH

------SRDYYRINGQAILPVRWMSPESLVYG-KFSIEGDVWSFGVVMWEVFSFALQPYYGLSNEEVTEAIRHG--KVLHRPDDCPSEVYNVMKECWDME
      . .||. ..| ..|.|||.||.|... .|..  ||||||||.||..... .|| |.||..|..... |    . .|.||| .||..|..|| ..
FSNRYWESYYYMAQHQDRWPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYD

AKSRPTFEELHTAL
   ||.||.|  ..
PQERPDFEDLVQQM
Kinase AqueK470.AA DDR 892-1175 38 1.4e-100 340.46 In-house 1-306 (306) Show / Hide 
Range on Protein: 892-1175
Range on HMM: 1-306/306
Sequence Identity: 38% (122 aa)

IQYAGQLGQGNFGIVFKGRAFGIA---SDDEEIE--------VAVKTLKEESSSEIRSNFIEEAKLMFSFD-HPNILHIYGVCMTEMPYQMVFEYMDE-G
      .|.| || |    ..|.    . |  ..        ||||.|... .   |  | .|.| | .   |||| .. |||... || |. |||   |
LIFVEKIGEGQFGEVHLCEVEGMQDYIEFDFHCDVHKGHPTLVAVKMLRPDACKHARNDFHKEIKCMSQCKRHPNIVRLVGVCTQDEPYCMIMEYMENLG

DLTQYLRSKASSMQRRLLNPFDHRSRTESSYSNDPPALSKTQLLSICRQIASGMEYLASKNHVHRDLACRNCLINSDLKVKIGDFG--MSRNLYSRDYYR
|| |..      |.. . |      . . .  .  | .| .....|| |||||| ||.| | |||||| ||||.  .. .|| |||  ||||||| ||||
DLNQFW------MEHEAENSGLMNCKADTQNCQK-PTISYECCVYICTQIASGMKYLESMNFVHRDLATRNCLVGKEYHIKICDFGTVMSRNLYSQDYYR

ING-----QAILPVRWMSPESLVYGKFSIEGDVWSFGVVMWEVFSFA-LQPYYGLSNEEVTEAI----RHGK---VLHRPDDCPSEVY-NVMKECWDMEA
. |      . .|.|||..||.. |||.   |||.||| |||.|.|.  |||  |..| | | .    ||..   .| .|  ||.|.| . |..||  . 
VEGFTGRQRHHMPIRWMAWESILLGKFTTKSDVWAFGVTMWEMFMFCREQPYEQLTDEQVIENACEFFRHQGMQVYLPMPPMCPYEIYNQLMCRCWRRDQ

KSRPTFEELHTAL
..||.|||.|. |
SQRPSFEEIHKFL
Kinase AqueK470.AA TK-Unique 892-1175 35 1.5e-98 333.74 In-house 1-294 (294) Show / Hide 
Range on Protein: 892-1175
Range on HMM: 1-294/294
Sequence Identity: 35% (107 aa)

IQYAGQLGQGNFGIVFKGRAFGIA-SDDEEIEVAVKTLKEESSSEIRSNFIEEAKLMFSFD-HPNILHIYGVCMTEM-PYQMVFEYMDEGDLTQYLRSKA
.    ..|.|.|| |..| ..||  ..|. . ||||.||.... . ...|  |...| . . ||||....|.|..   | ....||.  |.|  |||...
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR

SSMQRR----LLNPFDHRSRTESSYSNDPPA-LSKTQLLSICRQIASGMEYLAS--KNHVHRDLACRNCLINSDLKVKIGDFGMSRNLY-SRDYYRINGQ
  | .      |.       ...  . .... .|  .|.... |||.|||||||  |. |||||. ||.|...|...||.||||.| .|  ..| .. .|
PAMRQHQTYGNLK-----FDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMCSQ

AILPVRWMSPESLV--YGKF-SIEGDVWSFGVVMWEVFSFALQPYYGLSNEEVTEAIRHGKVLHRPDDC-PSEVYNVMKECWDMEAKSRPTFEELHTAL
  .|.|||.||||   .| . ....|||||||.|||.|..  .||.|...... |.|| |. . .|. | . |.||.||.||  |...||.|...   |
GRIPIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYRMPQPEHCCSHEMYNLMKSCWQWEPEERPSFRQIKHRL
Kinase AqueK470.AA Src 892-1175 34 1.8e-88 300.21 In-house 1-255 (255) Show / Hide 
Range on Protein: 892-1175
Range on HMM: 1-255/255
Sequence Identity: 34% (99 aa)

IQYAGQLGQGNFGIVFKGRAFGIASDDEEIEVAVKTLKEESSSEIRSNFIEEAKLMFSFDHPNILHIYGVCMTEMPYQMVFEYMDEGDLTQYLRSKASSM
|.   .||||.|| |..|        . ...|||||||. .       | .||..| ...|......| || .| |.  | ||| .| | .||.      
IKLCRKLGQGQFGEVWMGYW------NGNTKVAVKTLKPGT--MSPEAFLQEAQIMKKLRHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKK-----

QRRLLNPFDHRSRTESSYSNDPPALSKTQLLSICRQIASGMEYLASKNHVHRDLACRNCLINSDLKVKIGDFGMSRNLYS--RDYYRINGQAILPVRWMS
                  . .  .|. .||...  |.|.||.|| |.| .||||| || |.. .. .|..|||  | |     | |     | .|..|. 
------------------DGEGRHLHLPQLIDMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLAR-LIKEDDDEYCARHGAKFPIKWTA

PESLVYGKFSIEGDVWSFGVVMWEVFSFALQPYYGLSNEEVTEAIRHGKVLHRPDDCPSEVYN-VMKECWDMEAKSRPTFEELHTAL
|| . ||.|.|  ||||||. ..|....   || | .|.|| ... .|  . .|. || |.|. .|..||. ... ||||| |.  |
PEAINYGRFTIKSDVWSFGILLTEIVTYGRVPYPGMTNHEVLQQVERGYRMPCPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL
Kinase AqueK470.AA Ror 1015-1173 51 8.5e-84 284.7 In-house 115-273 (308) Show / Hide 
Range on Protein: 1015-1173
Range on HMM: 115-273/308
Sequence Identity: 51% (82 aa)

ALSKTQLLSICRQIASGMEYLASKNHVHRDLACRNCLINSDLKVKIGDFGMSRNLYSRDYYRINGQAILPVRWMSPESLVYGKFSIEGDVWSFGVVMWEV
.|..   | |  |||.|||||.|.  |||||| ||||..  ..||| ||| .|  || ||||. .....|.||||||.  |||||.. |.|||||| ||.
SLDHPDFLHIAIQIAAGMEYLSSHHFVHRDLAARNCLVGEHHHVKISDFGLMRDIYSSDYYRMQHKSWMPIRWMSPEAIMYGKFSEDSDIWSFGVVLWEI

FSFALQPYYGLSNEEVTEAIRHGKVLHRPDDCPSEVYNVMKECWDMEAKSRPTFEELHT
.|. .||||| || || | ||   .|  |..||  .|  | |||      ||.| . |.
WSYGMQPYYGYSNQEVIEMIRNRHLLPCPHNCPTWIYSLMIECWHEIPSRRPRFKDIHS
Kinase AqueK470.AA Tec 1016-1177 40 3.2e-62 213.01 In-house 92-254 (254) Show / Hide 
Range on Protein: 1016-1177
Range on HMM: 92-254/254
Sequence Identity: 40% (66 aa)

LSKTQ--LLSICRQIASGMEYLASKNHVHRDLACRNCLINSDLKVKIGDFGMSRNLYSRDYYRINGQAILPVRWMSPESLVYGKFSIEGDVWSFGVVMWE
..| .  ||..| ..  ||.|| ... .||||| ||||....  ||. ||||.|     .|    | .  ||.| .|| . | ..|   |||.||| |||
FQKNMAILLEMCQDVCEGMAYLERHCFIHRDLAARNCLVGDQCVVKVSDFGMTRYVLDDQYTSSVG-TKFPVKWCPPEVFHYSRYSSKSDVWAFGVLMWE

VFSFALQPYYGLSNEEVTEAIRHGKVLHRPDDCPSEVYNVMKECWDMEAKSRPTFEELHTALCQ
|||  ..||  .|| || |..  |  |.||. |. ..| .|..||  ... ||||..|  .. .
VFSCGKMPYENMSNSEVVEHVSQGHRLYRPHLCSMHIYQIMYHCWHEKPEERPTFQQLLRQITE
Kinase AqueK470.AA Pkinase 892-1175 20 1.3e-35 127.0 Pfam 1-293 (293) Show / Hide 
Range on Protein: 892-1175
Range on HMM: 1-293/293
Sequence Identity: 20% (69 aa)

IQYAGQLGQGNFGIVFKGRAFGIASDDEEIEVAVKTLKEESSSE-IRSNFIE--EAKLMFSFDHPNILHIYGVCMTEMPYQMVFEYMDEG----DLTQYL
..  ...|.|.|| |.|..  |        .||||..| .. ..  . . .   |...| ...||||. .|......  . ||.||.. |    ||  |.
YHIGRKIGSGSFGCVYKCHHKGTGK-----IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYI

RSKASSMQRRLLNPFDHRSRTESSYSNDPPAL--SKTQLLSICRQIASGMEYLASKNHVHRDLACRNCLINSDLKV----KIGDFGMSRNLYSRDYYRIN
.                          .  ..  |  .. ....||..|.||. |.. .||||   |.||...  .    ||.||| .. ..    |  |
ST------------------------WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD----Y-NN

GQAILPV---RWMSPESLV-YGKFSIEGDVWSFGVVMWEVFSFALQPYYGL------SNEEVTEAIRHGKVLHR-PDDCP-------------------S
. .  ..   ..|.|| .  . . . . |.||.|....|...    |..|       .  .. . |.....    | .|.                   .
S-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLC-GRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSE

EVYNVMKECWDMEAKSRPTFEELHTA--L
|   ..| |...  |.|||.|..     .
ECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase AqueK470.AA S_TKc 892-1179 20 1.5e-35 125.32 SMART 1-231 (231) Show / Hide 
Range on Protein: 892-1179
Range on HMM: 1-231/231
Sequence Identity: 20% (62 aa)

IQYAGQLGQGNFGIVFKGRAFGIASDDEEIEVAVKTLKEESSSEIRSNFIEEAKLMFSFDHPNILHIYGVCMTEMPYQMVFEYMDE--GDLTQYLRSKAS
 .   ..|.| || |.|.|  .        .||.| .|         ... | ... . .|||| ..|.|. .   . ||.||.|   ||| .|.... .
YEILRKIGKGAFGKVYKCRHKK-----TGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGR

SMQRRLLNPFDHRSRTESSYSNDPPALSKTQLLSICRQIASGMEYLASKNHVHRDLACRNCLINSDLKVKIGDFGMSRNLYSRDYYRINGQAILPVRWMS
   |. ... .                      ....||....||. |.. .||||   | |...   .||.|||..| |            .    .|.
HGLRFPFPE-H--------------------ARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMA

PESLVYGKFSI-EGDVWSFGVVMWEVFSFALQPYYGLSNEEVTEAIRHGKVLHRPDDCPSEVYNVMKECWDMEAKSRPTFEELHT-----ALCQFS
|| |   ...  . |.||.|....| ..    |..     .. . ... .        ..|. . .. |.... . |||  |. .     .. .. 
PEVL---GYGKCKCDWWSCGCILYEMLC-GYPPFP-----QMQMMFKKIG--------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK470.AA Ror 892-980 39 1.5e-26 94.54 In-house 1-89 (308) Show / Hide 
Range on Protein: 892-980
Range on HMM: 1-89/308
Sequence Identity: 39% (35 aa)

IQYAGQLGQGNFGIVFKGRAFGIASDDEEIEVAVKTLKEESSSEIRSNFIEEAKLMFSFDHPNILHIYGVCMTEMPYQMVFEYMDEGDL
..    || . || |.||  .| .  .. . ||.||.|.. |   .  |  |..|| ...||||  . |||  . || |.||||  |||
VRFMEELGECQFGKVYKGHLMGPNFMYHCMAVAIKTCKHDASPAQWQDFRQEIMLMATLHHPNIVCLLGVCTMDQPYCMLFEYMNHGDL
Kinase AqueK470.AA Tec 892-996 37 1.6e-20 68.49 In-house 1-99 (254) Show / Hide 
Range on Protein: 892-996
Range on HMM: 1-99/254
Sequence Identity: 37% (40 aa)

IQYAGQLGQGNFGIVFKGRAFGIASDDEEIEVAVKTLKEESSSEIRSNFIEEAKLMFSFDHPNILHIYGVCMTEMPYQMVFEYMDEGDLTQYLRSKASSM
.     ||.| ||.|  |.         ...||.|..|| | ||    |||||| |    ||.    ||||. . |  .|.|||  | |  |||..   .
LTFMKELGSGQFGVVHLGKW------RHQYDVAIKMIKEGSMSE--EDFIEEAKVMMKLSHPKLVQLYGVCSQQRPIYIVTEYMEHGCLLNYLREHKHHF

QRRL--L
|. .  |
QKNMAIL