Gene AqueK500 (A.queenslandica)

AqueK500

Species: A.queenslandica
Alias: AqueK500
External Links:
Annotation:

Classification

Group: TKL
Family: MLK
Subfamily: HH-a1

Sequence

Name Sequence Type Origin Length Description Download
AqueK500.AA Protein None 177 None Fasta, JSON
AqueK500.kin_dom Protein Kinase Domain None 136 None Fasta, JSON

Protein domain

Protein domains of AqueK500.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase AqueK500.AA TKL 42-177 24 4.9e-21 72.49 In-house 1-198 (364) Show / Hide 
Range on Protein: 42-177
Range on HMM: 1-198/364
Sequence Identity: 24% (49 aa)

LGRGSFGVVNELRVNG----------IQCAGKKLNNFL-----------------------AMEDSLLCEFGNAII-LHRQQHHPNIVKLFG-VHYPSS-
.|.|.||.|   . .|             | ||..                          ..| | ...| .  | .... .|||||.. | . .|.. 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

--------STPLPMLVMEYLPY-SLLQLIEGRVAINKEAILLDFANGLDYLHSKR------PPIIHRNIKASNILLTVGHN--------------AKITD
        ... ...|||| |  ||| ..       .  . || | |..||||..      ||||||..| .|||.    .              .||.|
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH---WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICD

L
.
F
Kinase AqueK500.AA TK 41-176 14 1.6e-20 64.81 In-house 6-294 (486) Show / Hide 
Range on Protein: 41-176
Range on HMM: 6-294/486
Sequence Identity: 14% (43 aa)

ELGRGSFG---VVNELRVNG---------------------------IQCAGKKLNNFLAMEDSLLCE--------------FGNAIILHRQ--QHHPNI
.||.| ||   .| . ...|                           ...| | |    ||..    .              . ... . ..   |||||
KLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLGHHPNI

VKLFG-VHYPSSST--------PLPMLVMEYLPY-----SLLQLIEGRVAINKEA---------------------------------------------
|.|.| .. . ...        . .|.|||| |.     ||..    .    ..                                              
VRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDYDDDLI

---------------------------------ILLDFANGLDYLHSKRP----PIIHRNIKASNILLTVGHN-----------AKITD
                                 . .. |.|. |||||.      ..||.. | |.|.. ...           .||.|
KDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIAD
Kinase AqueK500.AA STE 37-176 23 4e-17 57.11 In-house 1-190 (359) Show / Hide 
Range on Protein: 37-176
Range on HMM: 1-190/359
Sequence Identity: 23% (47 aa)

VTR-IELGRGSFG-VVNELRVN----------------GIQCAGKKLN------------------NFLAMEDSLLCEFGNAIILHRQQH-HPNIVKLFG
 ..  ..|.|.|| |.  ....                |  .| |..|                   .   ....| |     |... .| |||||| .|
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIK---IMKKCNHMHPNIVKYYG

VHY-----PSSSTPLPMLVMEYLP-YSLLQLIEGRVAINK-------------EAIL----LDFANG-LDYLHSKRPPIIHRNIKASNILLTVGHNAKIT
 ..      .. . |  ..|||..  || ..|. .  ..|             | ..     .   | |.||||..  |||| ||..||||     .|..
CYFKEGHNHKNDDEL-WICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH--IIHRDIKPANILL-----VKLC

D
|
D
Kinase AqueK500.AA CMGC 88-176 21 1.7e-13 39.83 In-house 94-247 (513) Show / Hide 
Range on Protein: 88-176
Range on HMM: 94-247/513
Sequence Identity: 21% (33 aa)

QQHHPNIVKLFGVHYPS-SSTPLP-------------MLVMEYLPYSLLQLIEGRVA-----------------------INKEAIL------LDFANGL
..||.|||||. . |.. | ....              ||.||....|.|.|.                            |.  ..          .||
NKHHNNIVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSEHENKHPHRRPPHNIKYFMIHIRYMYQILRGL

D--YLHSKRPPIIHRNIKASNILLTVG--------------------HNAKITD
.  |.||..  |||| .| .|||..                       . || |
KLKYCHSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICD
Kinase AqueK500.AA Dicty4-Unclassified 91-177 32 1.5e-12 39.31 In-house 57-153 (263) Show / Hide 
Range on Protein: 91-177
Range on HMM: 57-153/263
Sequence Identity: 32% (32 aa)

HPNIVKLFGVHY-PSSSTPLPMLVMEYLPY-SLLQLIE-----GRVAINKEA-----ILLDFANGLDYLHSKRPPIIHRNIKASNILLTVGHNAKITDL
||| ||. |    | |     . ||| ..   |. .|          |  .      . .| | |. .||..   .||| ||.||||.    |.|| |.
HPNLVKCYGYCINPRSHKSTMCIVMEFMHKGNLFEVIHSKPSEQQQPIKLDDTLIIKYAFDIAQGMQHLHTRN--FIHRDIKSSNILMDKHFNIKIADF
Kinase AqueK500.AA TKL-ciliate1 136-176 39 2.5e-12 38.48 In-house 108-148 (279) Show / Hide 
Range on Protein: 136-176
Range on HMM: 108-148/279
Sequence Identity: 39% (16 aa)

ILLDFANGLDYLHSKRPPIIHRNIKASNILLTVGHNAKITD
.. | | |. |||.. .|.|||..|  |||. .  . ||..
WCKDIAQGMQYLHMRQNPLIHRDLKMQNILYDEPYQYKICN
Kinase AqueK500.AA MLK 91-176 28 3e-12 38.93 In-house 64-176 (291) Show / Hide 
Range on Protein: 91-176
Range on HMM: 64-176/291
Sequence Identity: 28% (33 aa)

HPN----IVKLFGVHYPSSSTPL-PMLVMEYLPY-SLLQLIEG-RV------------AINKEAILLDF----ANGLDYLHS-KRPPIIHRNIKASNILL
|||    |... ||   ....|    .||||... ||  .. | |             .. . . ....    |.|..|||| ...||||| .| .|||.
HPNNHPCIIQFYGV---CLQPPCHFCIVMEYCEGGSLYNVLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILI

TV------GHNAKITD
.       . ..||.|
DEICHDMHHGTLKICD
Kinase AqueK500.AA TK-Unique 91-177 25 3.2e-12 38.56 In-house 63-177 (294) Show / Hide 
Range on Protein: 91-177
Range on HMM: 63-177/294
Sequence Identity: 25% (30 aa)

HPNIVKLFGVHYPSSSTPLPMLVMEYLPYS-LLQLIEGRVAINKEA-----------------------------ILLDFANGLDYLHSKRPPIIHRNIK
|||||...|.   |.    .|..|||.|.. |. ..  .    ..                              .. . |.|. ||.| |  |.||.. 
HPNIVQCLGCCTKSD--EPWMIIMEYCPCGNLQHYLRTCRPAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLC

ASNILLTVGHNAKITDL
|.|.||| ....||.|.
ARNVLLTEDKVCKICDF
Kinase AqueK500.AA STE-Unique 136-176 36 4.9e-12 38.48 In-house 408-453 (616) Show / Hide 
Range on Protein: 136-176
Range on HMM: 408-453/616
Sequence Identity: 36% (17 aa)

ILLDFANGLDYLHSKRPPIIHRNIKASNILLTVGH-----NAKITD
...  . ||.||||.. |||||..|..||... .      ..|| |
YTYQILEGLEYLHSQHNPIIHRDLKPHNIFCMQDGKGRVCKVKICD
Kinase AqueK500.AA SAMK 142-166 64 1.1e-11 33.53 In-house 114-138 (295) Show / Hide 
Range on Protein: 142-166
Range on HMM: 114-138/295
Sequence Identity: 64% (16 aa)

NGLDYLHSKRPPIIHRNIKASNILL
.. |||||  ||||||.|.. ||||
SAIDYLHSLNPPIIHRDINCDNILL
Pkinase AqueK500.AA Pkinase 36-176 26 3.1e-10 37.26 Pfam 1-155 (293) Show / Hide 
Range on Protein: 36-176
Range on HMM: 1-155/293
Sequence Identity: 26% (44 aa)

RVTRIELGRGSFGVVNELRVNGIQ--CAGKKLNNFLAMEDSL-----LCEFGNAIILHRQQHHPNIVKLFGVHYPSSSTPLPMLVMEYLPY-----SLLQ
 ..   .|.||||.| . .  | .   | |...   . .. .     |     . |..|  .|||||.|... . ...     .||||..      .|  
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRL---SEIQIMKRL-NHPNIVRLYDWFEDKDHIY---MVMEYCEGGLYVMDLFD

LIE----GRVAINKEAILLDFA----NGLDYLHSKRPPIIHRNIKASNILLT-VGHNA---KITD
.|.    |..    |  . ...     ||.|.||.   |||| .| .|||.   ||..   ||.|
YISTWRHGCFY-FSEWECKFYMYQILRGLEYCHSM--GIIHRDLKPENILIDNNGHIDACVKICD
Pkinase_Tyr AqueK500.AA Pkinase_Tyr 30-176 29 9.1e-10 33.7 Pfam 1-154 (270) Show / Hide 
Range on Protein: 30-176
Range on HMM: 1-154/270
Sequence Identity: 29% (48 aa)

LILQRVRVTRIELGRGSFGVVNELRVN------GIQCAGKKLNNFLAMEDS-LLCEFGNAIILHRQQ-HHPNIVKLFGVHY-PSSSTPLPMLVMEYLPY-
... ..      ||.|.||.| . . .      .|..| |.|..  ||..  .. .| . . . .|  ||||||.| || .  . .   ...|||| |. 
ITFGKK------LGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKE-GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPN-QIYIVMEYMPHG

SLLQLIEGR---VAINKEAILLDF----ANGLDYLHSKRPPIIHRNIKASNILLTVGHNAKITD
.||     .       .   ||..    |.|..||.||.  .||| . | |.|.| .. .||.|
DLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKN--CIHRDLAARNCLVTENNVVKICD
S_TKc AqueK500.AA S_TKc 36-177 16 9e-06 -92.29 SMART 1-231 (231) Show / Hide 
Range on Protein: 36-177
Range on HMM: 1-231/231
Sequence Identity: 16% (41 aa)

RVTRIELGRGSFGVVNELRVNG--IQCAGKKLNNFLAMEDSLLCEFGNAIILHRQQHHPNIVKLFGVHYPSSSTPLPMLVMEYLPY---SLLQLIEGRVA
     ..|.|.||.|   | ..   ..| |...          . . . | .... ||||||||..| .         .||||..    .|...|. |  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD----DHLYMVMEYCDGDLGDLFDYIKKRGR

------INKEA---ILLDFANGLDYLHSKRPPIIHRNIKASNILLTVGHNAKITD---------------------------------------------
      ..      ..   ...|.|.||.   |||| .| .||||.   . ||.|                                             
HGLRFPFPE-HARFYMYQICCALEYCHSH--GIIHRDLKPENILLDE--HIKICDFGLARQLTTFCGTPWYMAPEVLGYGKCKCDWWSCGCILYEMLCGY

--------------------------------------------------L
                                                  .
PPFPQMQMMFKKIGSPEAKDFIRKCLQKDPEKRPTAEALQDEWDIKCHPWF
TyrKc AqueK500.AA TyrKc 36-177 16 2.2e-05 -135.56 SMART 1-280 (280) Show / Hide 
Range on Protein: 36-177
Range on HMM: 1-280/280
Sequence Identity: 16% (48 aa)

RVTRIELGRGSFGVVNELRVNGIQCAGKKLNNFLAMEDSLLCEFGNAIILHRQ-QHHPNIVKLFGVHYPSS----STPLPMLVMEYLPY-SLLQLIEGRV
 .   .||.| ||.| . . . ||.| |.|..    .  .. |   | |...   ||||||.|.||   ..    . . .|.|||| |. .|.. .  . 
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA--REDFMRE---ARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR

AINKEAILLDF----ANGLDYLHSKRPPIIHRNIKASNILLTVGH--------------------------------NAK--------------------
   . . ||.|    |.| .|||||  ..||| . | |.|.. .|                                ..|                    
PKLCMKDLLSFCWQIACGMEYLHSK--NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTT

------------------------------------------------------------------------------------ITDL
                                                                                    . ..
KSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase AqueK500.AA STE-Unique 37-99 30 0.000506 9.52 In-house 1-68 (616) Show / Hide 
Range on Protein: 37-99
Range on HMM: 1-68/616
Sequence Identity: 30% (21 aa)

VTRIELGRGSFGVVNELR--VNGIQCAGKK--LNNFL-AMEDSLLCEFGNAIILHRQQHHPNIVKLFG
.  . .||||||.|.  .  ... .|| |.  |..|.    . |   . . | ..   ||.||||. |
NCQQMIGRGSFGNVHNCQNKKDCFRCAIKVIHLKQFKDFNQEPLVNMIISEIEIMKCLHHQNIVKYYG