Gene AqueK504 (A.queenslandica)

AqueK504

Species: A.queenslandica
Alias: AqueK504
External Links:
Annotation:

Classification

Group: TKL
Family: MLK
Subfamily: HH-a1

Sequence

Name Sequence Type Origin Length Description Download
AqueK504.AA Protein None 373 None Fasta, JSON
AqueK504.kin_dom Protein Kinase Domain None 197 None Fasta, JSON

Protein domain

Protein domains of AqueK504.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase AqueK504.AA TKL 25-271 19 3.7e-39 136.43 In-house 1-355 (364) Show / Hide 
Range on Protein: 25-271
Range on HMM: 1-355/364
Sequence Identity: 19% (72 aa)

LGRGSYGVVIEVIVNG----------QRCAGKKLHNL--ISEGQ-----------------------VARKFTEEALLHNMQHHPNIVDFLG--------
.|.|..|.|   . .|          .  | ||..     ..                            .. ||...... .||||| |.|        
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

-VYYAP--HSTLPTLVMEYLPMTLASCLESNNLKIQMKYAILLDVAKGLIYLHQKN------PCVIHRDLTANNVLLTHNL-------------LQAKIS
 | . |  ... . .|||| |     .|... . .. .  . ||.|.|. |||..|      | .|||||. .|.|.  |.               .||.
CVCMHPVGPWGQLCIVMEYCPG---GSLLHYLH-WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKIC

DLGMSRKW---------------------ADTMLTKAPGNIAVMPPEALEDNP---------------VYDHKLDVFSYGCLILHVLTGQFPQPTNQFK-
|.| || .                      .... .  |... |.||.|....                |. | ||.|.| ..  .||..       .. 
DFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCR-----PYYD

-PKPSRKSA----DDYIKVPECNRRSYYI---------EKLPQV-SDLTSLVKQCLSDDPTKRP
 | .... .    .. ..| . ..|              . |..  .. .| ..| . ||.|||
YPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRP
S_TKc AqueK504.AA S_TKc 19-284 21 1.3e-35 125.55 SMART 1-231 (231) Show / Hide 
Range on Protein: 19-284
Range on HMM: 1-231/231
Sequence Identity: 21% (61 aa)

EETGKELGRGSYGVVIEVIVNG--QRCAGKKLHNLISEGQVARKFTEEALLHNMQHHPNIVDFLGVYYAPHSTLPTLVMEYLPM---TLASCLESNN---
 | ....|.|..|.|  .. ..  ...| |...         ...  |  .. . |||||| ...|..    .   .||||..    .| . .....   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHG

----LKIQMKYAILLDVAKGLIYLHQKNPCVIHRDLTANNVLLTHNLLQAKISDLGMSRKWADTMLTKAPGNIAVMPPEALEDNPVYDH-KLDVFSYGCL
    .   .   ..  ....| |.|..   .|||||   |.||..   . ||.| |..|.      |   |    |.|| |     |.. | |. | ||.
LRFPFPE-HARFYMYQICCALEYCHSH--GIIHRDLKPENILLDE---HIKICDFGLARQL-----TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCI

ILHVLTGQFPQPTNQFKPKPSRKSADDYIKVPECNRRSYYIEKLPQVSDLTSLVKQCLSDDPTKRPEIKIASS-----IIEEFI
.   |.|. | |             .  .|.                ... .....||  ||.||| .  |        . ...
LYEMLCGYPPFP-----------QMQMMFKKIG-------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK504.AA TKL-Unique 21-203 29 1.6e-30 104.88 In-house 1-215 (290) Show / Hide 
Range on Protein: 21-203
Range on HMM: 1-215/290
Sequence Identity: 29% (63 aa)

TGKELGRGSYGVVIEVIVNGQRCAGKKLH-NLISEGQVARKFTEEALLHNMQH-HPNIVDFLGVYY--APHSTLPTLVMEYLPM-TLASCLE--------
 .. .|.|.||.|. .. .|   | |..| |  |. .. ..| .|  . .. | ||||| . |.     ..     .||||.|. .| . |         
FWNKIGEGGYGQVYKGKWRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNN

-SNNLKI--QMKYAILLDVAKGLIYLHQKNPCVIHRDLTANNVLLTHNL----LQAKISDLGMSRKWADTMLTKAP-----------GNIAVMPPEALED
 .||.|.  |... . .|.|.|..||| ..| .|||||.  |.|.. |.    ...||.| | |.  .  . ...            |..  |.|| |..
NNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLRM

N-PVYDHKLDVFSYG
|   |. | ||.|.|
NFCQYSEKSDVYSFG
Kinase AqueK504.AA TK 19-206 16 7.3e-30 96.68 In-house 1-384 (486) Show / Hide 
Range on Protein: 19-206
Range on HMM: 1-384/486
Sequence Identity: 16% (63 aa)

EETGKELGRGSYG---VVIEVIVNG---------------------------QRCAGKKLHNLISEGQVARK----------------FTEEALLHN-MQ
 . ||.||.| .|   .| . ...|                           ...| | |.   .. | ...                  |...... . 
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

HHPNIVDFLG------------VYYAPHSTLPTLVMEYLPMT-----LASCLESN---------------------------------------------
|||||| ..|            | .  |.  . .|||| |       | . | ..                                             
HHPNIVRLYGVCTQGEPKPCFEV-V-VHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQ

--------------------------------NLKIQMKYAILLDVAKGLIYLHQKNP----CVIHRDLTANNVLLTHNLL----------QAKISDLGM
                                .|  . .  . ...|.|. |||.||      ..|||| | |.|...|.           ..||.| |.
DYDDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGL

SR-------KWAD---TMLTKA----PGNIAV-----------------------MPPEALEDNP--------VYDHKLDVFSYGCLI
||       .  .      .|     ....                         |.||.|.|.         .. .| ||.|.|.|.
SRQGSGVLARDIYSDDDYYRKSSYGTGRPM-WPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLM
Kinase AqueK504.AA MLK 19-215 24 5.2e-29 97.85 In-house 1-235 (291) Show / Hide 
Range on Protein: 19-215
Range on HMM: 1-235/291
Sequence Identity: 24% (58 aa)

EETGKELGRGSYGVVIEVIVNGQR-----CAGKKLH-NLISEGQV----ARKFTEEALLHNMQHHPN----IVDFLGVYYAPHSTLPTLVMEYLPM-TLA
 .. . .| ||.|.|      ...      | |. . . . . ..    ...| .|. . ..  |||    |. |.||   | . .  .||||..   |.
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHF-CIVMEYCEGGSLY

SCLESNN---------------LKIQMKYAILLDVAKGLIYLHQKNP-CVIHRDLTANNVLLTH-----NLLQAKISDLGMSRKWADT-M-LTKAPGNIA
. | ...                . . .  . |..|.|. |||.. |  .|||||   |.|...     . ...||.| | ||.| ..    ....|. |
NVLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMMSNAGTYA

VMPPEALE--DNPVYDHKLDVFSYGCLILHVLTGQFP
 | ||...   .  |. | ||.|.| ..  .||.. |
WMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVP
Pkinase AqueK504.AA Pkinase 19-289 20 1.4e-27 98.55 Pfam 1-293 (293) Show / Hide 
Range on Protein: 19-289
Range on HMM: 1-293/293
Sequence Identity: 20% (64 aa)

EETGKELGRGSYGVVIEVIVNGQRC-----AGKKLHNLISEGQVARKFTEEALLHNMQHHPNIVDFLGVYYAPHSTLPTLVMEYLPMTLASCLESN----
 ..|. .|.||.|.| . .  | ..       || |.  .. | .|. .| ...... .||||| ......  .. .  .||||....|  ...      
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFED-KDHIY-MVMEYCEGGLY-VMDLFDYIS

---NLKI--QMKYA--ILLDVAKGLIYLHQKNPCVIHRDLTANNVLLTHNLLQA----KISDLGMSR---KWADTMLTKAPGNIAVMPPEALEDNPVYDH
   . ..  ... .  ... ...|| |.|..   .|||||   |.|.  |  .     ||.| | ..      .. .|   | .  |.|| . ... |..
TWRHGCFYFSEWECKFYMYQILRGLEYCHSM--GIIHRDLKPENILID-NNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGP

KLDVFSYGCLILHVLTGQFPQPTNQFKPKPSRKSADDYIKVPECNRRSYYIEKLPQV-----------------SDLTSLVKQCLSDDPTKRPEIKIASS
| |..|.||..  .|.|..| |     ... .     . .. ..  .. . .. .                   ... ...| ||  ||.|||       
KVDMWSCGCILYEMLCGRPPFPGHC-WHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT------

IIEEFISHVVV
 .|.   |  .
-AEQILQHPWF
Kinase AqueK504.AA Ciliate-E2 19-274 16 4.9e-26 86.35 In-house 1-357 (365) Show / Hide 
Range on Protein: 19-274
Range on HMM: 1-357/365
Sequence Identity: 16% (64 aa)

EETGKELGRGSYGVVIEVIVNGQRC-------------------AGKKLHNLISE--GQVARKFTEEALLHNMQH---------------HPNIVDFLGV
 .  | .|.|..|.| .. |  ...                   . .|. .. .    |.  .. |. ..  ...               ||||. .  .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

YYAPHSTLPTLVMEYLPM-TLASCLESNNLK----------IQMKYA--ILLDVAK---------------GLIYLHQKNPCVIHRDLTANNVLLTHNLL
..    .   |||||.   .| .....|..|          . .| .  |   ...               .| |||.||. .||||.  .|.|.     
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNN-IIHRDIKPENILF-----

QAKISDLGMSRKWAD-----------TMLTKAP-----------------------GNIAVMPPEALEDNPV--------YDHKLDVFSYGCLILHVLTG
  ||.|.|.|.|  |            ...                          |.   |.|| |.  .         ||.| |..| |...   |.|
-IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFG

QFPQPTNQFKPKPSRKSADDYIKVPECNRRSYYIEKLPQVSDLT--------------------------SLVKQ----CLSDDPTKRPE-IK
..|                             ..... .  |.                            | |.    .|  || ||.  ..
KPPF----------------------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWE
Kinase AqueK504.AA Pkinase_Tyr 20-206 29 1.3e-25 87.38 Pfam 2-204 (270) Show / Hide 
Range on Protein: 20-206
Range on HMM: 2-204/270
Sequence Identity: 29% (62 aa)

ETGKELGRGSYGVVIEVIVN------GQRCAGKKLHNLISEGQ-VARKFTEEA-LLHNMQHHPNIVDFLGVYY--APHSTLPTLVMEYLPM-TLASCLES
. ||.||.|..|.| . . .      .. .| |.| .  .. |   ..| .|| ..... |||||| ..|| .    ..  . .|||| |   | . | .
TFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPN-QIYIVMEYMPHGDLLDYLRK

N-----NLKIQMKYAILLDVAKGLIYLHQKNPCVIHRDLTANNVLLTHNLLQAKISDLGMSRKW----AD-TMLTKAPGNIAVMPPEALEDNPVYDHKLD
.     .|.....  . ...|||. ||..||   ||||| | |.|.|.|. ..||.| |..|         .. ....  |  |.||.. ..  . .| |
HREDKQPLTMKDLLQMCWQIAKGMEYLESKN--CIHRDLAARNCLVTENN-VVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGK-FTTKSD

VFSYGCLI
| |.| |.
VWSFGVLM
Kinase AqueK504.AA STE 19-271 18 1.9e-25 86.92 In-house 1-346 (359) Show / Hide 
Range on Protein: 19-271
Range on HMM: 1-346/359
Sequence Identity: 18% (69 aa)

EETGKELGRGSYGVVIEVIVN-----------------GQRCAGKKLH----------------NLISEGQVARKFTEEALLHNMQH-HPNIVDFLGVYY
 |  ...|.|..|.|   . .                 |...| |...                . . . .. .   |  ......| ||||| ..| |.
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

AP------HSTLPTLVMEYLP-MTLASCLESN-NLKIQMK--------------YAILLDVAKG-LIYLHQKNPCVIHRDLTANNVLLTHNLLQAKISDL
        ...|  ..|||..  .| . ....   . ...               .|. .. || | |||...  .||||. . |.||      .|..| 
KEGHNHKNDDEL-WICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH--IIHRDIKPANILL------VKLCDF

GMSRKWADTML------------TKA-PGNIAV----MPPEALED-----NPVYDHKLDVFSYGCLILHVLTGQFP----QPT--NQFKPKPSRKSA---
| . . .|.|             | .   |  |    | || ..      .. || | |. | ||.|.. .||. |    .|.     .|. .....   
GVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTPWMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFE

------DDYIKVPE-----CNRRSYYIEKLPQV------------SDLTSLVKQCLSDDPTKRP
      ..  . |.     .  .|        .            ...   ...||  || |||
QLCIVNGPPPPLPDHLSQNEM-IS--------YGGSGTTYPHKWSPEFKDFINKCLQKDPNKRP
Kinase AqueK504.AA TK-Unique 20-206 25 9e-25 82.43 In-house 2-229 (294) Show / Hide 
Range on Protein: 20-206
Range on HMM: 2-229/294
Sequence Identity: 25% (59 aa)

ETGKELGRGSYGVVIEVIVNG-------QRCAGKKLHNLISEGQ-VARKFTEEALLHNMQHHPNIVDFLGVYYAPHSTLPTLVMEYLPMT-LASCLESNN
| |...|.|..| |.   | |       |.|.  |...  . .. ..  . | ... .   |||||..||.   .    . ..|||.|.  | ..| .. 
EVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSD-EPWMIIMEYCPCGNLQHYLRTCR

---------------------------LKIQMKYAILLDVAKGLIYLHQ--KNPCVIHRDLTANNVLLTHNLLQAKISDLGMSR-----KWADTMLTKAP
                           .. .  | .. ..|.|. ||..  |.  ..|||| | |||||.. ...||.|.||.|     .  ..| .. .
PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKK--IVHRDLCARNVLLTED-KVCKICDFGMARDVYTNGVYSMMCSQGR

GNIAVMPPEALE--DNPVYDHKLDVFSYGCLI
  |. |.||.|   ... .  | || |.|.|.
IPIRWMAPESLKCYHGMYHTTKSDVWSFGVLM
Kinase AqueK504.AA LRRK 19-215 23 1e-23 80.75 In-house 1-282 (351) Show / Hide 
Range on Protein: 19-215
Range on HMM: 1-282/351
Sequence Identity: 23% (68 aa)

EETGKELGRGSYG-VVIEVIVNG----------------------------QRCAGKKLHN--------------------------------LISEGQV
 . ....|||..| .|   ...|                            |  | ||..                                 ...   .
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

ARKFTEEALLHNMQHHPNIVDFLGVYYAPHSTLPTLVMEYLPM-TLASCLESNN----------LKIQMKYAILLDVAKGLIYLHQKNPCVIHRDLTANN
 |.|  |. . .  .|||||. .|.   |    ...||||.|  .| . |...           .. ..|. | |..|||. ||| .|| .|||||.  |
FREFRHEVWIMSHLNHPNIVSLKGFCIHP----LCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNPPIIHRDLKSPN

VLL-TH----------NLLQAKISDLGMSR--KWADTM-LTKAPGNIAVMPPEALEDN--PVYDHKLDVFSYGCLILHVLTGQ-FP
.|| ..          .   |||.| | ||  .   .  . .  ||.  | || . .|   .|. | |..|.| .. . ||.| .|
ILLWSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHP
Kinase AqueK504.AA HH498 110-215 38 7.7e-23 68.89 In-house 117-225 (284) Show / Hide 
Range on Protein: 110-215
Range on HMM: 117-225/284
Sequence Identity: 38% (42 aa)

NLKIQMKYAILLDVAKGLIYLHQ-KNPCVIHRDLTANNVLLTHNLLQAKISDLGMSR---KWADTMLTKAPGNIAVMPPEALEDNPVYDHKLDVFSYGCL
..  | |  | .|||.|  |||    . .|||||.  |.|. |    |.. | | ||      |  .|| |||   | ||    .  |. | |||||.  
IMDLQSKMTISVDVAHGMNYLHNSLKHPIIHRDLNSHNILI-HEDGHAVVADFGESRFVCDMHDDNMTKQPGNLRWMAPEVFSQCQKYSIKVDVFSYAMC

ILHVLTGQFP
|   .|.  |
IWEMHTREVP
Kinase AqueK504.AA Ciliate-E2-Unclassified 19-220 18 4.7e-21 69.79 In-house 1-274 (352) Show / Hide 
Range on Protein: 19-220
Range on HMM: 1-274/352
Sequence Identity: 18% (52 aa)

EETGKELGRGSYGVVIEVIVNGQR--------CAGKKLH-NLISEGQVARKFTEEALLHNM---------------QHHPNIVDFLGVYYAPHSTLPTLV
 . .| .|.|..|.| ... . |         .  .. . ..| . .   .. ....  ..               ..||...    .|.      . .|
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

MEYLPM-TLASCLESNNL-------------------KIQMKY----AILLDVAKGLIYLHQKNPCVIHRDLTANNVLLTHNLL--QAKISDLGMSR---
|||..  .|  ......                      |.||     ..  . .|| |||.||  .||||.. .|.|.. |    . ||.|.| |.   
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKN-NIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQ

--------------KWADTMLTKAPGNIAVM----PPEALEDNPVYD---HKLDVFSYGCLILHVLTGQFPQPTNQ
               | . |..   |..  |    .|| |. .  ..   .| |..| |...   |.|..| . |.
QNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNN
Kinase AqueK504.AA TyrKc 19-280 26 9.2e-18 64.47 SMART 1-280 (280) Show / Hide 
Range on Protein: 19-280
Range on HMM: 1-280/280
Sequence Identity: 26% (78 aa)

EETGKELGRGSYGVVIEVIVNGQRCAGKKLHNLISEGQVARKFTEEA-LLHNM-QHHPNIVDFLGVYYAP-----HSTLPTLVMEYLPM-TLASCLESNN
 . ||.||.| .|.| . . . . .| |.|..        . | .|| ....   |||||| ..||   .      .  . .|||| |   | . | .. 
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR

--LKIQMKYAILLDVAKGLIYLHQKNPCVIHRDLTANNVLLTHNLLQAKISDLGMSRKWADT--------MLTK-----AP--GNIAVMPPEALEDNPVY
  |. . .  . ...|.|  |||.|  ..||||| | |.|...|. ..|||| |.||.. |         . .|     .     |  |.||.. .  ..
PKLCMKDLLSFCWQIACGMEYLHSK--NCIHRDLAARNCLVGENH-TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-NYGKF

DHKLDVFSYGCLILHVLT-GQFPQPTNQFKPKPSRKSADDYIKVPECNRRSYYIEKLPQ---------VSDLTSLVKQCLSDDPTKRPEIKIASSII
 .| ||.|.| ..  ..| || | |   ..         . . | |. .. |. .. |           ... .. |||   || .||  .   ...
TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQ-------MMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase AqueK504.AA LRRK 254-282 24 0.009648 5.51 In-house 323-351 (351) Show / Hide 
Range on Protein: 254-282
Range on HMM: 323-351/351
Sequence Identity: 24% (7 aa)

DLTSLVKQCLSDDPTKRPEIKIASSIIEE
.. .| ..| . ||.|||      .....
MYQDLIQHCWQHDPKKRPHFSQIVKRLSQ
Kinase AqueK504.AA MLK 257-283 37 0.017802 4.56 In-house 268-291 (291) Show / Hide 
Range on Protein: 257-283
Range on HMM: 268-291/291
Sequence Identity: 37% (10 aa)

SLVKQCLSDDPTKRPEIKIASSIIEEF
.| ||| ..|| |||  .   .|....
KLMKQCWNQDPHKRPSFR---QIVQHL
Kinase AqueK504.AA TK-Unique 254-280 22 0.019109 4.39 In-house 268-294 (294) Show / Hide 
Range on Protein: 254-280
Range on HMM: 268-294/294
Sequence Identity: 22% (6 aa)

DLTSLVKQCLSDDPTKRPEIKIASSII
....| |.|....|..|| .    ...
EMYNLMKSCWQWEPEERPSFRQIKHRL
Kinase AqueK504.AA TKL-Unique 254-271 38 0.371631 0.05 In-house 264-281 (290) Show / Hide 
Range on Protein: 254-271
Range on HMM: 264-281/290
Sequence Identity: 38% (7 aa)

DLTSLVKQCLSDDPTKRP
... | .||  .||..||
EYRDLIQQCWHHDPSQRP