AqueK515

Species: A.queenslandica
Alias: AqueK515
External Links:
Annotation:

Classification

Group: TKL
Family: MLK
Subfamily: HH-a2

Sequence

Name Sequence Type Origin Length Description Download
AqueK515.AA Protein None 281 None Fasta, JSON
AqueK515.kin_dom Protein Kinase Domain None 78 None Fasta, JSON

Protein domain

Protein domains of AqueK515.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase AqueK515.AA TKL 203-274 25 3.6e-19 65.66 In-house 1-118 (364) Show / Hide
Range on Protein: 203-274
Range on HMM: 1-118/364
Sequence Identity: 25% (30 aa)

LGRGAFGTVRIGKFRG----------QSVAVKQLYAELQSPENI-------------------------SRINREIDILSQLRHPNIVQFIGAILDHP--
.|.|.||.|  ||.||          . ||||..  .  . ...                          ....|| ..|.|||||||||.|. .. |  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

---------DGNPRIITE
         .|.. |..|
CVCMHPVGPWGQLCIVME

Kinase AqueK515.AA LISK 202-260 40 1.7e-18 56.5 In-house 1-64 (296) Show / Hide
Range on Protein: 202-260
Range on HMM: 1-64/296
Sequence Identity: 40% (26 aa)

ELGRGAFGTVRIGKFR--GQSVAVKQLYA---ELQSPENISRINREIDILSQLRHPNIVQFIGA
|.|.|.|| |  |  |  || .|.|..      .  ||..  ..||. ..  |||||||||.|.
EIGKGFFGKVYKGTHRQTGQVMAIKMIHRQPNDPNDPEYQKFMLREVQMMKNLRHPNIVQFMGV

Kinase AqueK515.AA DRK 200-274 42 8.8e-18 56.84 In-house 4-77 (258) Show / Hide
Range on Protein: 200-274
Range on HMM: 4-77/258
Sequence Identity: 42% (32 aa)

QQELGRGAFGTVRIGKFRGQSVAVKQLYAELQSPENI-SRINREIDILSQLRHPNIVQFIGAILDHPDGNPRIITE
.   ||| .| |  |  ||  |||| | .     ||. .   |||....|||||||.||.|. .  ||  . |..|
GNRIGRGNYGEVFRGTWRGTQVAVKMLFNHNINDENFLNEFHREINLMCQLRHPNICQFMGTCNNPPD--ICICME

Pkinase_Tyr AqueK515.AA Pkinase_Tyr 196-274 33 9.7e-18 60.71 Pfam 1-87 (270) Show / Hide
Range on Protein: 196-274
Range on HMM: 1-87/270
Sequence Identity: 33% (30 aa)

VTLSQQELGRGAFGTVRIGKFR------GQSVAVKQLYAELQSPEN--ISRINREIDILSQL-RHPNIVQFIGAIL--DHPDGNPRIITE
.|.  ..||.||||.|. |. .      .. |||| |  |  ..|.  .    ||. |..|| .|||||...|...  . |  .. |..|
ITFG-KKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPN-QIYIVME

Kinase AqueK515.AA Dicty4 200-260 39 3.7e-17 53.95 In-house 4-66 (277) Show / Hide
Range on Protein: 200-260
Range on HMM: 4-66/277
Sequence Identity: 39% (25 aa)

QQELGRGAFGTVRIGKFRGQSVAVKQLYAELQS--PENISRINREIDILSQLRHPNIVQFIGA
.|..|.|.||.|  |. ||. |||| | .  |    . ..   .|..|....|||||..| ||
EQRIGKGSFGEVYKGTWRGKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGA

Kinase AqueK515.AA MLK 197-274 28 1.3e-16 54.24 In-house 1-90 (291) Show / Hide
Range on Protein: 197-274
Range on HMM: 1-90/291
Sequence Identity: 28% (26 aa)

TLSQQELGRGAFGTVRIGKFRGQS-----VAVKQLYAEL----QSPENISRINREIDILSQLRHPN----IVQFIGAILDHPDGNPRIITE
 . .. .| |.|| |  |..|..      ||||.  |.     .. . .  ...|. .|. |.|||    |.|| |..|..|  .  |..|
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPP-CHFCIVME

Kinase AqueK515.AA CAMK 202-261 18 3.3e-16 48.05 In-house 1-107 (425) Show / Hide
Range on Protein: 202-261
Range on HMM: 1-107/425
Sequence Identity: 18% (20 aa)

ELGRGAFGTVRIGKFR-GQS-------------VAVKQLYAELQS--------------------------PENISRINREIDILSQ-------LRHPNI
.||||.||.|. .. .  .              ||.| .  .  .                          |..  .. |||.|...       |.||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VQFIGAI
.... ..
IKLYEVY

Kinase AqueK515.AA Gdt 203-259 38 1.5e-14 46.22 In-house 7-68 (289) Show / Hide
Range on Protein: 203-259
Range on HMM: 7-68/289
Sequence Identity: 38% (24 aa)

LGRGAFGTVRIGKFRGQSVAVKQLYAELQS-----PENISRINREIDILSQLRHPNIVQFIG
.. | ||.| .|..|...|||| .  .           .  | ||.|||| ..|.||| |||
CSQGTFGMVYKGIWRSSQVAVKMFKHHYVNYTKTYSQSCDEIYREMDILSKIKHQNIVSFIG

Kinase AqueK515.AA TKL-Unique 199-274 35 2.6e-14 47.03 In-house 1-80 (290) Show / Hide
Range on Protein: 199-274
Range on HMM: 1-80/290
Sequence Identity: 35% (28 aa)

SQQELGRGAFGTVRIGKFRGQSVAVKQLYA-ELQSPENISRINREIDILSQLR-HPNIVQFIGAILDHPDGNP--RIITE
    .|.|..|.|  ||.|| .||.||.   |..|.| .   ..|. ... |. |||||...|.  ||   .|   |..|
FWNKIGEGGYGQVYKGKWRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVME

Kinase AqueK515.AA STE 197-263 22 3e-14 46.85 In-house 1-101 (359) Show / Hide
Range on Protein: 197-263
Range on HMM: 1-101/359
Sequence Identity: 22% (23 aa)

TLSQQELGRGAFGTVRIGKFR-----------------GQSVAVKQLYAELQSP---------------ENISRINREIDILSQLR--HPNIVQFIGAIL
   ....|.||||||  .. .                 |. .|.||.  | ...               |.. .| .||.|.....  |||||...|. .
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

D
.
K

Kinase AqueK515.AA LISK-DD1 202-260 40 6.5e-14 46.9 In-house 1-65 (290) Show / Hide
Range on Protein: 202-260
Range on HMM: 1-65/290
Sequence Identity: 40% (26 aa)

ELGRGAFGTVRIGKFRGQSVAVKQLYA---ELQSPENISRINREIDILSQ---LRHPNIVQFIGA
| |.|.|| |  |   |  ||.|..      .  |. .  ..||| .|     .||||||||||.
EIGKGSFGKVYKGCYFGTPVAIKKIHKQPNDPNDPDYWKFMQREIKMLKNLLNIRHPNIVQFIGI

Kinase AqueK515.AA Pkinase 197-274 25 1.8e-13 48.68 Pfam 1-80 (293) Show / Hide
Range on Protein: 197-274
Range on HMM: 1-80/293
Sequence Identity: 25% (21 aa)

TLSQQELGRGAFGTVRIGKFRGQS--VAVKQLYAELQSP-ENISRIN-REIDILSQLRHPNIVQFIGAILDHPDGNPRIITE
    . .|.|.||.|.... .| .  ||||..  . ... ....... .|| |.  |.|||||.....  |  .... ...|
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED--KDHIYMVME