Gene AqueK537 (A.queenslandica)

AqueK537

Species: A.queenslandica
Alias: AqueK537
External Links:
Annotation:

Classification

Group: TKL
Family: MLK
Subfamily: HH-a2

Sequence

Name Sequence Type Origin Length Description Download
AqueK537.AA Protein None 659 None Fasta, JSON
AqueK537.kin_dom Protein Kinase Domain None 260 None Fasta, JSON

Protein domain

Protein domains of AqueK537.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
MIF4G AqueK537.AA MIF4G 26-264 29 5.8e-48 170.46 Pfam 1-237 (237) Show / Hide 
Range on Protein: 26-264
Range on HMM: 1-237/237
Sequence Identity: 29% (79 aa)

FRKFQGILNKLT--PQNFKKLAEQARELEIDN--EERLKGCVDIIFLNVFKGPMFCEAYAQMCRVLSFIKVEIVMRDDDGDDECKKVMKETTFRRELLSL
..| .||.||||  |.||.|...| |.| ...  .. .|  ...|| ..   | || .||..|..|.    ..               ..|.||. ||  
CKKVNGIINKLTEDPDNFDKIIDQLRKLNWSDYNKNCRKYIIRCIFQKAVEEPNFCPMYARLCARLNHHMPRF---------------NKTDFREHLLNR

CQREFEKDKRDNKAKEEMLKAIEIAAPGEKEDKEAELKELENVAHRNSLANHRFLGELFKLKMLSESIMHECIVRLLRSECD---------NEALERFCV
|| ||.|...|. ..             .|.|.|... |.| ....  |.| ||..||....|..|.|.||||  ||.. ..          . .|  | 
CQEEFQKWWKDDECH-------------MKPDQEMMMEENERMNYQRCLNNVRFICELYNFQMIHEKIIHECIYHLLNHCTEECQQWQPRDDFNIECICM

LITVTGKKLD--HPQAKQRMDRYFERINEIIEK-----------KKIELRTRFMLLDVQDLRKND
..| .||.||  |...|..||..|||.  ....           .... |.||||.|. .||||.
FLTWCGKYLDFNHEKSKKQMDQFFERMQDYKWHWDKSHVNWWHPPELSPRIRFMLEDLIELRKNK
MIF4G AqueK537.AA MIF4G 26-264 26 7.6e-43 149.57 SMART 1-227 (227) Show / Hide 
Range on Protein: 26-264
Range on HMM: 1-227/227
Sequence Identity: 26% (69 aa)

FRKFQGILNKLTPQNFKKLAEQARELEIDN----------EERLKGCVDIIFLNVFKGP------MFCEAYAQMCRVLSFIKVEIVMRDDDGDDECKKVM
 .| .||.|||||.||...... ..| .||          .. .| ....||  .   |       || .||..|..|.                     
EKKVNGIINKLTPDNFEDIIKELCYLNWDNMRERDPQENDKNCRKYIIECIFQKAMEEPGNQDKMNFCPMYARLCALLHHCMP-----------------

KETTFRRELLSLCQREFEKDKRDNKAKEEMLKAIE-IAAPGEKEDKEAELKELENVAHRNSLANHRFLGELFKLKMLSESIMHECIVRLLRSECDNEALE
   .|...||  || ||||...|  ..|. .. .  .. . |. ..| .. ..|  .... ..| ||..||....|....|...||  ||..... . .|
---DFGKHLLNRCQEEFEKNWDD-ECHEK-FQPKQMMCDHMEE-KWE-MMEYEEQMNYQRCRNNVRFICELYNFQMITSKIIFHCIYMLLNDCTH-FNIE

RFCVLITVTGKKLDHPQAKQRMDRYFERINEIIEKKKIELRTRFMLLDVQDLRKND
  | ... .||.|| .....|||..|.|.. ...   .. |.||||.|. .||||.
CLCMFLPWCGKDLD-EKSPKRMDQIFQRMQDYFW---LSPRIRFMLEDWIELRKNK
Kinase AqueK537.AA TKL 403-656 22 8.2e-56 191.73 In-house 1-364 (364) Show / Hide 
Range on Protein: 403-656
Range on HMM: 1-364/364
Sequence Identity: 22% (86 aa)

LGSGGWGEVIIGKFHG----------QQVAVKRFYE------SIMNQKN---------------IEYYFQMLNREMATLSQLHHPNLLQFIGAVLDDP--
.|||| |||  ||..|          . ||||.| .      ....|.|               .. ... ...|.  .|.|.|||..||.|.... |  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

---------SGNPMIITEVM-DTSLRSAYEKKELTPDPACRPVILSIMRDVAVGLSYLHCLL------DPIIHRDVSSANVLLESKGP----------GK
         .|...|..| .   ||.. .            ........|.| |..|||          ||||||  |.|.|. ...             
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH----------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNAD

WKTKISDFGLAK----------------------MARSATTKAVGAMVYSAPECLQTVVDFEE----------SKQSPKADVFSYGILLCEVITCRFPEH
|. ||.||||..                      . |..| . .|   . |||.|.   ...|          .. |.|.||.|.||.|.|..|.. |..
WCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYY

QI---------------FRVLLDQVRSS--------------GGSGSSLHSLVVSCGTKDPEKRPTMKQIIEQL
..                 | ... |                     |. .|   |   ||||||....|...|
DYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase AqueK537.AA TK 397-656 17 9.1e-38 123.66 In-house 1-486 (486) Show / Hide 
Range on Protein: 397-656
Range on HMM: 1-486/486
Sequence Identity: 17% (83 aa)

TLSRHKLGSGG---WGEVIIGKFHG---------------------------QQVAVKRFYE-SIMNQKNIEYYFQM----------LNREMATLSQ--L
    .|||.|    .|||  |. .|                           ..||||   | . |.|.  . .. .          . .||. ...  .
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

HHPNLLQFIGAVLDDPS----------GNPMIITEVMD-TS----LRSAYEKKE----------------------------------------------
||||.....|..... .          . .||..| |.  .    ||.   |.                                               
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

------LTPDPACRPVILS-------------------IMRDVAVGLSYLHCLLD----PIIHRDVSSANVLLESKGPGKWK-------TKISDFGLAK-
      . |.| .    |.                   .....| |..||| .       ..|||.   |.|. .... ||.        ||.||||.. 
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQ

----MAR-----SATTKAV------------------------GAMV---YSAPECLQTVVDFEE---SKQSPKADVFSYGILLCEVIT---CRFPE---
    .||     .  ...                         |...   . |||||.. |  |     | ..| ||.|.|.|. |. |     ...   
GSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMS

----------HQIFRVL-----------------LDQVRSSGGSG-------------SSLHSLVVSCGTKDPEKRPTMKQIIEQL
          ..... |                 . . .  . .                .. |  .|  .|||.|||..|. |||
NQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase AqueK537.AA MLK 397-609 27 1.1e-34 117.81 In-house 1-235 (291) Show / Hide 
Range on Protein: 397-609
Range on HMM: 1-235/291
Sequence Identity: 27% (66 aa)

TLSRHKLGSGGWGEVIIGKFHGQQ-----VAVKRFYESIMNQKNIEY-YFQMLNREMATLSQLHHPN----LLQFIGAVLDDPSGNPMIITEVMDT-SLR
 .  ...|||. |.|  |.....      |||||.  .|   | ..|   . ...|   |. | |||      || |. |..|  .  |..| ..  || 
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPP-CHFCIVMEYCEGGSLY

SAYEKKELTPDPAC----------RPVILSIMRDVAVGLSYLHCLL-DPIIHRDVSSANVLLES--KGPGKWKTKISDFGLAK-MARS-A-TTKAVGAMV
.    ..  ...|             ...... ..| |..|||... .||||||  | |.|.    .  .. . ||.|||... . .. .  ... |   
NVLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMMSNAGTYA

YSAPECLQTVVDFEESKQSPKADVFSYGILLCEVITCRFP
. ||| .|    |...| | |.||.|.|..| |..|.. |
WMAPEVIQQ---FRCEKYSEKCDVWSWGVVLWEMLTREVP
Kinase AqueK537.AA TKL-Unique 401-605 29 7.5e-31 106.1 In-house 3-223 (290) Show / Hide 
Range on Protein: 401-605
Range on HMM: 3-223/290
Sequence Identity: 29% (67 aa)

HKLGSGGWGEVIIGKFHGQQVAVKRFYESIMNQKNIEYYFQMLNREMATLSQLH-HPNLLQFIGAVLDDPSGNP--MIITEVMDT-SLRSAYE-------
 |.|.|| |.|. ||..| .||.|.|  .. | .      | ...|  ... || |||.....|.  |.   .|   |..| ..  ||..          
NKIGEGGYGQVYKGKWRGYPVAIKQF--HP-NEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNN

--KKELTPDPACRPVILSIMRDVAVGLSYLHCLLDPIIHRDVSSANVLLESK-GPGKWKTKISDFGLAKMAR--SATTKA----------VGAMVYSAPE
  .........   ..... .|.| |. ||| .  ||||||  | |.|. ..    .|. ||.||||.| .   ...|.           .|   ..|||
NNNNNCKLNMQ---QRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPE

CLQTVVDFEESKQSPKADVFSYGILLCEVIT
 |  .     .. | |.||.|.|| | | .|
VLRMNF----CQYSEKSDVYSFGIVLWEIAT
Kinase AqueK537.AA S_TKc 397-659 22 1.2e-30 109.04 SMART 1-231 (231) Show / Hide 
Range on Protein: 397-659
Range on HMM: 1-231/231
Sequence Identity: 22% (63 aa)

TLSRHKLGSGGWGEVIIGKFHG--QQVAVKRFYESIMNQKNIEYYFQMLNREMATLSQLHHPNLLQFIGAVLDDPSGNPMIITEVMDT---SLRSAYEKK
     |.|.|. |.|  .. ..  ..||.|.               ... ||.. |.. ||||. .....  |   ..  ...| .|.   .|..  .|.
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------------EHIRREIQILKK-HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKR

EL--TPDPACRPVILSIMRDVAVGLSYLHCLLDPIIHRDVSSANVLLESKGPGKWKTKISDFGLAKMARSATTKAVGAMVYSAPECLQTVVDFEESKQSP
    .. |    .. ..|. .. .| |.| .   |||||.  .|.|| .        ||.|||||.      |  .|   | ||| |         . ..
GRHGLRFPFPE-HARFYMYQICCALEYCHSH--GIIHRDLKPENILLDE------HIKICDFGLARQL----TTFCGTPWYMAPEVL---------GYGK

-KADVFSYGILLCEVITCRFPEHQIFRVLLDQVRSSGGSGSSLHSLVVSCGTKDPEKRPTMKQIIE------QLDHI
 |.|. | |..| | .. . | .    .......      ... ...  | .||||||||  .. .      .   .
CKCDWWSCGCILYEMLCGYPPFP-QMQMMFKKIG-----SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK537.AA CZAK 401-609 30 1.2e-28 101.2 In-house 5-221 (279) Show / Hide 
Range on Protein: 401-609
Range on HMM: 5-221/279
Sequence Identity: 30% (69 aa)

HKLGSGGWGEVIIGKFHGQQVAVKRFYESIMNQKNIEYYFQMLNREMATLSQLHHPNLLQFIGA-VLDDPSGNPMIITEVMD-TSLRSAYEKKE--LTPD
   | |  |||  .   |  ||.|  .      |       |  .| . .| | ||| .||.||  .| |     |..| |   |||     .   . . 
QTIGQGFFGEVYKAYWRGKDVAIKIIHRNQFRNKDENKEENMFQKEVSIMSKLCHPNCVQFLGACSEDGP-NHHCIVMEWMGGGSLRRLLTDHYFYHKQN

PACRPVILSIMRDVAVGLSYLHC-LLD-PIIHRDVSSANVLLESKGP---------GKWKTKISDFGLA---KMARSATTKAVGAMVYSAPECLQTVVDF
|  .   ... .|.| |  |||      ||.||| || |.||..               . ||.||||    .   .  | ..| . . ||||      |
PHLQ---WNMAIDIARGMNYLHDNWKPNPILHRDLSSRNILLDHSYTPKNPVVSSRQDIICKINDFGLSREMMEQPFEMTQTMGCLCWMAPEC------F

EESKQSPKADVFSYGILLCEVITCRFP
     ..|.||.|.|..| ..|||. |
KGENYTEKVDVYSFGMILWCIITCDQP
Kinase AqueK537.AA Dicty4 400-606 29 9.9e-27 86.31 In-house 4-213 (277) Show / Hide 
Range on Protein: 400-606
Range on HMM: 4-213/277
Sequence Identity: 29% (67 aa)

RHKLGSGGWGEVIIGKFHGQQVAVKRFYESIM---NQKNIEYYFQMLNREMATLSQLHHPNLLQFIGAVL--DDPSGNPMIITEVM-DTSLRSAYEK---
  ..|.|. |||  |.  |..||||     ..   ||.  |.  . . .| . .... |||...| || .     .| ..| || |  ..| |   .   
EQRIGKGSFGEVYKGTWRGKEVAVK-----KLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPS

---KELTPDPACRPVILS---IMRDVAVGLSYLHCLLDPIIHRDVSSANVLLESKGPGKWKTKISDFGLAK-----MARSA-TTKAVGAMVYSAPECLQT
   .. ..|    | |..   ...|.| |. .|||    |||||  |.| |        |. |..||||..        .. .. |.|   . |||... 
EQQQSIKLD---WPLIKRAMRMAFDAARGMNWLHCCNPVIIHRDLKSHNLLVDK----NWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMH

VVDFEESKQSPKADVFSYGILLCEVITC
   . |     ||||.|.||.| |  |.
Q-PYNE-----KADVYSFGIVLWEILTR
Kinase AqueK537.AA Pkinase 402-656 22 4.3e-26 93.35 Pfam 6-293 (293) Show / Hide 
Range on Protein: 402-656
Range on HMM: 6-293/293
Sequence Identity: 22% (68 aa)

KLGSGGWGEVIIGKFHGQQ--VAVKRFYESIMNQKNIEYYFQMLNREMATLSQLHHPNLLQFIGAVLDDPSGNPMIITEVMDT-----SLRSAYE---KK
|.|||. |.| ... .| .  ||||..  .  . .  .. .    .| . .  |.||| ....... |  .... ...| ..      .| .  .   ..
KIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRL--SEIQIMKRLNHPNIVRLYDWFED--KDHIYMVMEYCEGGLYVMDLFDYISTWRHG

EL--TPDPACRPVILSIMRDVAVGLSYLHCLLDPIIHRDVSSANVLLESKGPGKWKT----KISDFGLAK---MARSATTKAVGAMVYSAPECLQTVVDF
 .  ...     .. ..|. .. || |.|     |||||. ..|.|. ..|     .    ||.||||||     .. .|  .|   | ||| ..     
CFYFSEW-----ECKFYMYQILRGLEYCHSM--GIIHRDLKPENILIDNNG----HIDACVKICDFGLAKQFDY-NNSMTTFCGTPWYMAPEVIR-----

EESKQSPKADVFSYGILLCEVIT--CRFPEH----------QIFRVLLDQVRSSGGSG---------------------SSLHSLVVSCGTKDPEKRPTM
. .. .||.|..|.|..| |...    ||.|           |.|..  .....                         ... ... .| .|||.|||| 
GGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTA

KQIIEQ--L
.|| .   .
EQILQHPWF
Kinase AqueK537.AA STE 398-651 19 6.9e-26 88.47 In-house 1-350 (359) Show / Hide 
Range on Protein: 398-651
Range on HMM: 1-350/359
Sequence Identity: 19% (72 aa)

LSR-HKLGSGGWGEVIIGKFH-----------------GQQVAVKRFYESIMNQKNIE------------YYFQMLNREMATLSQLH--HPNLLQFIGAV
. .  |.|.|. |.|  .. |                 |. .|.|.   .  |.|. |              .| . .|. ......  |||  ...|. 
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKD-ENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCY

LDD---PSG--NPMIITEVMD-TSLRSAYE-K-KELTPDPACR--------PVILSIMRDVAVG-LSYLHCLLDPIIHRDVSSANVLLESKGPGKWKTKI
...    .   .  |. | ||  ||.. .. | . . |..  |        ..|  | |..  | |.||| .   |||||. .||.||          |.
FKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH--IIHRDIKPANILL---------VKL

SDFGLAKMARS-------------------ATTKAVGAMVYSAPECLQT-VVDFEESKQSPKADVFSYGILLCEVITCRFPEHQIF--RVLLDQVRS---
.|||...   .                    ..  ||   . ||| .|    .  ... . |.|. | |....| .| . | |     |...   ..   
CDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQG-RDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHM

-----------------SGGSG-------------------SSLHSLVVSCGTKDPEKRPTMKQ
                                         ....  .  | .|||.|||| .|
QQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQ
Kinase AqueK537.AA TyrKc 397-656 23 2.8e-20 74.59 SMART 1-280 (280) Show / Hide 
Range on Protein: 397-656
Range on HMM: 1-280/280
Sequence Identity: 23% (72 aa)

TLSRHKLGSGGWGEVIIGKFHGQQVAVKRFYESIMNQKNIEYYFQMLNREMATLSQL--HHPNLLQFIGAVLDD-----PSGNPMIITEVMDT-SLRSAY
    .|||.|  |||  |.   .|||||   |.           ... ||.  ...|  ||||.....|.....      .. .||..| |.  .|..  
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA---------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYL

EKKELTPDPACRPVILSIMRDVAVGLSYLHCLLDPIIHRDVSSANVLLESKGPGKWKTKISDFGLAKMARSA-------TTKAV----GAM--V---YSA
 |.. .    | .  ||.. ..| | .|||    ..||||    |.|. ...      |||||||..   .         .. .    |.   .     |
RKHRPK---LCMKDLLSFCWQIACGMEYLHSK--NCIHRDLAARNCLVGENH----TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMA

PECLQTVVDFEESKQSPKADVFSYGILLCEVIT------CR-----FPEHQIFRVLLDQVRSSGGSG----------SSLHSLVVSCGTKDPEKRPTMKQ
|||.       ..| ..| ||.|.|... |. |              .  .... . .  |                . ....  .|   |||.|||...
PECI------NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSE

IIEQL
|.|..
IHECF
Kinase AqueK537.AA HH498 501-609 35 5e-15 43.71 In-house 121-225 (284) Show / Hide 
Range on Protein: 501-609
Range on HMM: 121-225/284
Sequence Identity: 35% (41 aa)

PVILSIMRDVAVGLSYLHC-LLDPIIHRDVSSANVLLESKGPGKWKTKISDFG----LAKMARSATTKAVGAMVYSAPECLQTVVDFE-ESKQSPKADVF
. .. |  ||| |  |||  |  ||||||  | |.|.   |    . .. |||    .  |     ||  |   . |||       |    | | |.|||
QSKMTISVDVAHGMNYLHNSLKHPIIHRDLNSHNILIHEDG----HAVVADFGESRFVCDMHDDNMTKQPGNLRWMAPEV------FSQCQKYSIKVDVF

SYGILLCEVITCRFP
||.. . |  | . |
SYAMCIWEMHTREVP
Kinase AqueK537.AA DRK 501-605 34 1.1e-14 46.13 In-house 98-197 (258) Show / Hide 
Range on Protein: 501-605
Range on HMM: 98-197/258
Sequence Identity: 34% (38 aa)

PVILSIMRDVAVGLSYLHCLLDPIIHRDVSSANVLLESKGPGKWKTKISDFGLAK-----MARSATTKAVGAMVYSAPECLQTVVDFEESKQSPKADVFS
| ....| |.| |. ||||    |||||  | | |        |. |..||||.        . ..  ..|     ||| |      |      ||||.|
PLMKQMMFDCAKGMIYLHCCNPIIIHRDLKSHNLLVDE----HWQVKVADFGLSTRFKKHKQHKFAMTMCGTPCWTAPEVLRNQRYTE------KADVYS

YGILLCEVIT
..| | |..|
FAIVLWECVT
Pkinase_Tyr AqueK537.AA Pkinase_Tyr 396-478 30 4.1e-14 48.44 Pfam 1-87 (270) Show / Hide 
Range on Protein: 396-478
Range on HMM: 1-87/270
Sequence Identity: 30% (28 aa)

VTLSRHKLGSGGWGEVIIGKFH------GQQVAVKRFYESIMNQKNIEYYFQMLNREMATLSQL-HHPNLLQFIGAVL--DDPSGNPMIITE
.|.  .|||.|  |||  |. .      ...||||   |. | . |   . ... ||.....|| ||||.....|...  ..|. ...|..|
ITFG-KKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQN---CREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPN-QIYIVME
Kinase AqueK537.AA Dicty4-Unclassified 502-605 30 3.3e-13 41.53 In-house 110-203 (263) Show / Hide 
Range on Protein: 502-605
Range on HMM: 110-203/263
Sequence Identity: 30% (32 aa)

VILSIMRDVAVGLSYLHCLLDPIIHRDVSSANVLLESKGPGKWKTKISDFGLAKMARSATT-KAVG-AMVYSAPECLQTVVDFEESKQSPKADVFSYGIL
.|. .  |.| |. .||     .||||. |.|.|.          || |||..       .  ...      .||||       ||  . |.||.||...
LIIKYAFDIAQGMQHLHTR--NFIHRDIKSSNILMDK----HFNIKIADFGISRVIDFNFNMTTIAGTPKWESPECLM-----HESYNQ-KSDVYSYAMM

LCEVIT
| | .|
LYELAT
Kinase AqueK537.AA HH498 400-470 35 4.1e-12 34.3 In-house 4-76 (284) Show / Hide 
Range on Protein: 400-470
Range on HMM: 4-76/284
Sequence Identity: 35% (26 aa)

RHKLGSGGWGEVIIGKFHGQQVAVKRFYESIMNQKNI--EYYFQMLNREMATLSQLHHPNLLQFIGAVLDDPS
  | |||  |.|  |.. .  |||||.  .    |     .   |. ||   ...| ||.  ||..| .||||
HEKIGSGSFGKVYKGEWRNKIVAVKRYRAMAFCCKSDSYQWIVDMFCREVSIMCRLNHPCVVQFVYACCDDPS
Kinase AqueK537.AA Pkinase_Tyr 503-609 28 3.2e-10 35.22 Pfam 113-214 (270) Show / Hide 
Range on Protein: 503-609
Range on HMM: 113-214/270
Sequence Identity: 28% (33 aa)

ILSIMRDVAVGLSYLHCLLDPIIHRDVSSANVLLESKGPGKWKTKISDFGLAKMA--RSAT-TKAVGAMV---YSAPECLQTVVDFEESKQSPKADVFSY
.|.. ...| |..||.    ..||||.   |.|...   .. . ||.|||||.     .   .|. |...     ||||... .       . | || |.
LLQMCWQIAKGMEYLE--SKNCIHRDLAARNCLVTE---NN-VVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGK------FTTKSDVWSF

GILLCEVIT-CRFP
|.|. |..| .. |
GVLMWEIFTYGEQP
Kinase AqueK537.AA DRK 404-480 36 1.3e-09 28.79 In-house 8-79 (258) Show / Hide 
Range on Protein: 404-480
Range on HMM: 8-79/258
Sequence Identity: 36% (28 aa)

GSGGWGEVIIGKFHGQQVAVKRFYESIMNQKNIEYYFQMLNREMATLSQLHHPNLLQFIGAVLDDPSGNPMIITEVM
| |..|||  |   | |||||.      |  |.    . . ||   ..|| |||  ||.|. .  |.  . |..| |
GRGNYGEVFRGTWRGTQVAVKMLFNHNINDENF---LNEFHREINLMCQLRHPNICQFMGTCNNPPD--ICICMEYM
Kinase AqueK537.AA Dicty4 630-658 35 5.4e-09 26.32 In-house 247-277 (277) Show / Hide 
Range on Protein: 630-658
Range on HMM: 247-277/277
Sequence Identity: 35% (11 aa)

SLHSLVVSCGTKDPEKRPTMKQIIEQ--LDH
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SWKHLIQWCWDHDPQHRPSFEEIIQRRILEH
Kinase AqueK537.AA Dicty4-Unclassified 633-656 54 1.4e-08 25.46 In-house 240-263 (263) Show / Hide 
Range on Protein: 633-656
Range on HMM: 240-263/263
Sequence Identity: 54% (13 aa)

SLVVSCGTKDPEKRPTMKQIIEQL
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KLIKWCWHNDPNKRPTMNQIIQYL
Kinase AqueK537.AA Dicty4-Unclassified 400-480 28 5e-06 16.71 In-house 4-84 (263) Show / Hide 
Range on Protein: 400-480
Range on HMM: 4-84/263
Sequence Identity: 28% (25 aa)

RHKLGSGGWGEVIIGKFHGQQVAVKRFYESIMNQKNIEYYFQMLNREMATLSQLHHPNLLQFIGAVLDDPSGNP-------MIITEVM
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DQFIGKGHFSKVHKGNWKGKDVAVKKFNENKFKFR--EEMIQDFKKEVEILGSIQHPNLVKCYGYCI-----NPRSHKSTMCIVMEFM
Kinase AqueK537.AA MLK 642-656 53 5e-06 17.0 In-house 277-291 (291) Show / Hide 
Range on Protein: 642-656
Range on HMM: 277-291/291
Sequence Identity: 53% (8 aa)

DPEKRPTMKQIIEQL
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DPHKRPSFRQIVQHL
Kinase AqueK537.AA DRK 634-658 36 8.9e-05 12.15 In-house 234-258 (258) Show / Hide 
Range on Protein: 634-658
Range on HMM: 234-258/258
Sequence Identity: 36% (9 aa)

LVVSCGTKDPEKRPTMKQIIEQLDH
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LMNDCWNEDPQHRPSMQECLERLEA
Kinase AqueK537.AA TKL-Unique 638-656 42 0.000168 12.0 In-house 272-290 (290) Show / Hide 
Range on Protein: 638-656
Range on HMM: 272-290/290
Sequence Identity: 42% (8 aa)

CGTKDPEKRPTMKQIIEQL
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CWHHDPSQRPSFDEIIHRL
Kinase AqueK537.AA Pkinase_Tyr 641-656 62 0.000234 15.38 Pfam 255-270 (270) Show / Hide 
Range on Protein: 641-656
Range on HMM: 255-270/270
Sequence Identity: 62% (10 aa)

KDPEKRPTMKQIIEQL
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YDPEDRPTFSEIHEQL
Kinase AqueK537.AA CZAK 634-656 43 0.000845 9.86 In-house 257-279 (279) Show / Hide 
Range on Protein: 634-656
Range on HMM: 257-279/279
Sequence Identity: 43% (10 aa)

LVVSCGTKDPEKRPTMKQIIEQL
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LIEMCWNKNPDERPSFKQILQHL
Kinase AqueK537.AA HH498 633-656 37 0.007915 4.35 In-house 261-284 (284) Show / Hide 
Range on Protein: 633-656
Range on HMM: 261-284/284
Sequence Identity: 37% (9 aa)

SLVVSCGTKDPEKRPTMKQIIEQL
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NLIQMCWHPCPENRPDFDQIVTIL