Gene AqueK577 (A.queenslandica)

AqueK577

Species: A.queenslandica
Alias: AqueK577
External Links:
Annotation:

Classification

Group: TKL
Family: MLK
Subfamily: HH-C

Sequence

Name Sequence Type Origin Length Description Download
AqueK577.AA Protein None 312 None Fasta, JSON
AqueK577.kin_dom Protein Kinase Domain None 119 None Fasta, JSON

Protein domain

Protein domains of AqueK577.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

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Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase AqueK577.AA Dicty4 194-301 32 1.3e-23 75.74 In-house 3-129 (277) Show / Hide 
Range on Protein: 194-301
Range on HMM: 3-129/277
Sequence Identity: 32% (41 aa)

TKEELGRGSYAVVTVGIFRGLRVAVKSL--HNIIISDYNLGIFSREMSIASRVRHPNLVQFIGA-T----KVGNPLILTELM-STSLNRELRR------N
. ...|.||.. |  |. ||  |||| |  ||.  . . |  | .| .| .  ||||...| || |    . | ..| ||.| ...| . |.        
IEQRIGKGSFGEVYKGTWRGKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSEQQQ

RLSNQ--QILS---IAQDVALGLNYLH
. . .   |..   .| |.|.|.|.||
SIKLDWPLIKRAMRMAFDAARGMNWLH
Kinase AqueK577.AA TKL 198-310 24 1.4e-22 78.14 In-house 1-163 (364) Show / Hide 
Range on Protein: 198-310
Range on HMM: 1-163/364
Sequence Identity: 24% (41 aa)

LGRGSYAVVTVGIFRG----------LRVAVKSLHNIIISDYNL-------------------------GIFSREMSIASRVRHPNLVQFIGATK-----
.|.|....|  |..||            |||| ..    .  ..                           . .|. . || ||||.|||.|. .     
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

---------VGNPLILTELM-STSLNRELRRNRLSNQQILSIAQDVALGLNYLHLFKP-----QPIIH
          |.. | .|..   ||   |       .|....|.|.|.|.||||  .|      ||||
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-----WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIH
Kinase AqueK577.AA MLK 192-310 25 5.3e-19 62.67 In-house 1-150 (291) Show / Hide 
Range on Protein: 192-310
Range on HMM: 1-150/291
Sequence Identity: 25% (38 aa)

TLTKEELGRGSYAVVTVGIFRGLR-----VAVKSLHNIIISDYNL-----GIFSREMSIASRVRHPN----LVQFIGA-TKVGN-PLILTELMST-SLNR
 ...| .| ||. .|  | .|. .     ||||  .  |. |          | .|  ......|||     .|| |. .. ..  .|..| ..  ||..
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYN

ELRRNR---------------LSNQQILSIAQDVALGLNYLHLFKPQPIIH
 |. .|                . ......| ..| |..|||  .|.||||
VLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIH
Kinase AqueK577.AA TK 192-301 13 7.7e-18 55.66 In-house 1-251 (486) Show / Hide 
Range on Protein: 192-301
Range on HMM: 1-251/486
Sequence Identity: 13% (34 aa)

TLTKEELGRGSYA---VVTVGIFRGL---------------------------RVAVKSLH---NIIISDYNLGIFS---------REMSIASRVR----
    ..||.| .    .|  |. ||.                           .|||| |.   .    .  . ..          .|.....  .    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HPNLVQFIG-ATKVGN------------PLILTELMS-TS----LNRELRRNR----------------------------------------------
 |||.|...|  |....            ..|..|.|.  .    |   ||..|                                              
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------LSNQQILSIAQDVALGLNYLH
                               |. .| | .....| |. |||
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLH
Kinase AqueK577.AA TKL-Unique 194-310 30 1.9e-17 58.26 In-house 1-135 (290) Show / Hide 
Range on Protein: 194-310
Range on HMM: 1-135/290
Sequence Identity: 30% (41 aa)

TKEELGRGSYAVVTVGIFRGLRVAVKSLH-NIIISDYNLGIFSREMSIASRVR-HPNLVQFIGATK---VGNP--LILTELMST-SLNRELR--------
  . .|.|.|..|  |..||  ||.|..| |  .|   .  |..| .. .. . |||.|...|...   | .|   | .| ..  ||.  |         
FWNKIGEGGYGQVYKGKWRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNN

---RNRLSNQQILSIAQDVALGLNYLHLFKPQPIIH
    . |..||....|.|.|.|..|||  .|  |||
NNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPP-IIH
Kinase AqueK577.AA CZAK 193-310 33 1.9e-15 52.67 In-house 1-132 (279) Show / Hide 
Range on Protein: 193-310
Range on HMM: 1-132/279
Sequence Identity: 33% (44 aa)

LTKE-ELGRGSYAVVTVGIFRGLRVAVKSLHNIIISDYNL----GIFSREMSIASRVRHPNLVQFIGATKVGN---PLILTELMS-TSLNRELR-RNRLS
|. . . |.| .  |  .  ||  ||.| .| .   .        .| .| || |  .||| |||.||   ..     | .| |   || | |  .  . 
LKFGQTIGQGFFGEVYKAYWRGKDVAIKIIHRNQFRNKDENKEENMFQKEVSIMSKLCHPNCVQFLGACSEDGPNHHCIVMEWMGGGSLRRLLTDHYFYH

NQ---QILSIAQDVALGLNYLHL-FKPQPIIH
 |     ...| |.| | ||||  .|| ||.|
KQNPHLQWNMAIDIARGMNYLHDNWKPNPILH
Pkinase_Tyr AqueK577.AA Pkinase_Tyr 191-301 26 6.9e-15 51.04 Pfam 1-128 (270) Show / Hide 
Range on Protein: 191-301
Range on HMM: 1-128/270
Sequence Identity: 26% (34 aa)

VTLTKEELGRGSYAVVTVGIFR------GLRVAVKSLHNIIISDYN--LGIFSREMSIASRV-RHPNLVQFIGATK-VGNP---LILTELMST-SLNREL
.|.  ..||.|.. .|  |. .      .. ||||.| .   .. .  .  | ||..| .   .|||.|...|.    | |   .| .|.|   .|   |
ITFG-KKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

RRN-----RLSNQQILSIAQDVALGLNYLH
|..     .|. ...|......| |..||.
RKHREDKQPLTMKDLLQMCWQIAKGMEYLE
Kinase AqueK577.AA DRK 199-301 37 1.7e-14 45.58 In-house 8-115 (258) Show / Hide 
Range on Protein: 199-301
Range on HMM: 8-115/258
Sequence Identity: 37% (40 aa)

GRGSYAVVTVGIFRGLRVAVKSLHNIIISDYN-LGIFSREMSIASRVRHPNLVQFIGA-TKVGNPLILTELMST-SLNRELRRNRLSNQ--QILSIAQDV
|||.|. |  |  ||  |||| | |  | | | |  | ||  . .. |||| .||.|. .    ..| .| |.  || . |    .. .   ..... |.
GRGNYGEVFRGTWRGTQVAVKMLFNHNINDENFLNEFHREINLMCQLRHPNICQFMGTCNNPPDICICMEYMPRGSLYNILHDESIEMDWPLMKQMMFDC

ALGLNYLH
| |..|||
AKGMIYLH
Kinase AqueK577.AA STE 193-310 17 1.1e-13 44.8 In-house 1-175 (359) Show / Hide 
Range on Protein: 193-310
Range on HMM: 1-175/359
Sequence Identity: 17% (31 aa)

LTK-EELGRGSYAVVTVGIFR-----------------GLRVAVKSLH---------------NIIISDYNLGIFSREMSIASRVR--HPNLVQFIGATK
... |..|.|.. .|  .. .                 | ..|.| ..               . .. . ..  . .|..| .. .  ||| |...|.  
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

VG--------NPLILTELMS-TSLNRELRRN---------------RLSNQQILSIAQDVALG-LNYLHLFKPQPIIH
..        .  |  |.|.  ||   ....               |.. .||  |....  | |.|||  .   |||
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH---IIH
Kinase AqueK577.AA Shk 193-301 33 2.1e-13 44.6 In-house 1-118 (269) Show / Hide 
Range on Protein: 193-301
Range on HMM: 1-118/269
Sequence Identity: 33% (40 aa)

LTKEE-LGRGSYAVVTVGIFRGLRVAVKSLHNIIISDYNLGIFSREMSIASRVRHPNLVQFIGA-T-KVGNPLILTELM-STSLNRELRRNRLSNQ--QI
 ..|. || ||.  |  |. ||  |||| .|    . . .  |  | .| |...|||.. | || | . |   | ||||  ..|   |.  .       .
INREDFLGQGSFGKVYKGRCRGKEVAVKVMHKQNFDENTMTSFRKEVHIMSKIFHPNICLFMGACTSQPGKCMIVTELMPKGNLEKLLHDQMVKKPFILY

LS---IAQDVALGLNYLH
.    .. | ||| | ||
KRAMRMCRDAALGMNWLH
Kinase AqueK577.AA LISK 197-301 31 1e-12 37.47 In-house 1-118 (296) Show / Hide 
Range on Protein: 197-301
Range on HMM: 1-118/296
Sequence Identity: 31% (37 aa)

ELGRGSYAVVTVGIFR--GLRVAVKSLH---NIIISDYNLGIFSREMSIASRVRHPNLVQFIGATKV-GNPL-ILTELMST-SLNRELRRN-----RLSN
|.|.|... |  |  |  |  .|.| .|   |  . . ..  . ||. .  . |||| |||.|. .     | |.||...   | . |...      |. 
EIGKGFFGKVYKGTHRQTGQVMAIKMIHRQPNDPNDPEYQKFMLREVQMMKNLRHPNIVQFMGVCYHNDGQLHIVTEYINGGDLHQYLKDMDKHKIPLPW

QQILSIAQDVALGLNYLH
.| ..|| |.|.|. |||
PQRVKIALDIACGMSYLH
Kinase AqueK577.AA Pkinase 192-301 19 4.4e-10 36.73 Pfam 1-125 (293) Show / Hide 
Range on Protein: 192-301
Range on HMM: 1-125/293
Sequence Identity: 19% (24 aa)

TLTKEELGRGSYAVVTVGIFRGLR--VAVKSLHNIIISDYNLGIFSR--EMSIASRVRHPNLVQFIGATK-VGNPLILTELMST-----SLNRELR---R
  ... .|.||...|  .. .| .  |||| .    ...  . .  |  | .|  |..||| |.....    ... . .|..       .| . ..   .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

NRL--SNQQILSIAQDVALGLNYLH
...  | ... ...  .. ||.|.|
GCFYFSEWECKFYMYQILRGLEYCH
Kinase AqueK577.AA S_TKc 192-309 7 6.6e-05 -104.99 SMART 1-231 (231) Show / Hide 
Range on Protein: 192-309
Range on HMM: 1-231/231
Sequence Identity: 7% (19 aa)

TLTKEELGRGSYAVVTVGIFRG--LRVAVKSLHNIIISDYNLGIFSREMSIASRVRHPNLVQFIGATKVGNPLILTELMST---SLNRELRRNR------
    ...|.|....|  .. ..   .||.| ..           . ||..| .. .|||.|.....   ..  . .|....   .| . .....      
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-LSNQQILSIAQDVALGLNYLH------------------------------------------------------------------------------
 ..  .. .... ....|.|.|                                                                              
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDEHIKICDFGLARQLTTFCGTPWYMAPEVLGYGKCKCDWWSCGCILYEMLCGYPPFPQMQMM

---------------LFKP-------------------QPII
               ...                     | .
FKKIGSPEAKDFIRKCLQKDPEKRPTAEALQDEWDIKCHPWF
Kinase AqueK577.AA TyrKc 192-309 12 0.000189 -150.68 SMART 1-280 (280) Show / Hide 
Range on Protein: 192-309
Range on HMM: 1-280/280
Sequence Identity: 12% (35 aa)

TLTKEELGRGSYAVVTVGIFRGLRVAVKSLHNIIISDYNLGIFSREMSIASRV--RHPNLVQFIGATKV--------GNPLILTELMST-SLNRELRRNR
   ...||.| . .|  |. . . ||||.|..       .  | ||..| ...  .|||.|...|.           . ..|..|.|.  .|.  ||..|
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR

--LSNQQILSIAQDVALGLNYLH-----------------------------------------------------------------------------
  |.... ||.. ..| | .|||                                                                             
PKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKS

------------------------------------------LFKPQP------------------------------------II
                                          . .|.                                     ..
DVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF