Gene AqueK603 (A.queenslandica)

AqueK603

Species: A.queenslandica
Alias: AqueK603
External Links:
Annotation:

Classification

Group: TKL
Family: MLK
Subfamily: HH-C

Sequence

Name Sequence Type Origin Length Description Download
AqueK603.AA Protein None 1308 None Fasta, JSON
AqueK603.kin_dom Protein Kinase Domain None 203 None Fasta, JSON

Protein domain

Protein domains of AqueK603.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
7tm_1 AqueK603.AA 7tm_1 29-172 20 6.9e-17 53.01 Pfam 1-142 (263) Show / Hide 
Range on Protein: 29-172
Range on HMM: 1-142/263
Sequence Identity: 20% (30 aa)

ANGVVLSITLYQRKSLKQPSTIFFTSLILAHLVLILLNLPFIIVGLAAG-KWIFTGSDEEETGTCYFALYIFWWMVLVISTTLAAISVDRFLFIVKPHLH
 |..|. . .....    |. .|. .| .| | . |...|.... .. |  | |          | .  |.| . . .   .|..||.||.. |..|  .
GNILVIWVICRHKRMR-TPTNYFICNLAVADLLFCLTCPPWMLYYFHWGHHWPFGR------AMCKIWTYFFYMCCYASIFFLCCISIDRYWAICHPMRY

NRFMK-PWVALTLTIAIWILSAVYTTFYIFGLDFDLYQFN---SSFCFL
.|.|  |..|. . ..||.|... .   ... .  . ...     .|..
RRRMTPPRHAWVMCLVIWVLAFLWSLPPLMFWWCYTHECPNWNHCWCYI
WD40 AqueK603.AA WD40 227-267 10 0.013459 12.17 SMART 1-46 (46) Show / Hide 
Range on Protein: 227-267
Range on HMM: 1-46/46
Sequence Identity: 10% (5 aa)

ENKELTALSNIHNS--PILFMKYNSHY------DVIVSADSTGMLEYWS
. | .  ..  |..  ... ......       ....|..  | .  |.
T-KCVHTFK-GHTGNSWVTCVCWHPDGGSDDYPNYLASGS-DGTIRIWD
WD40 AqueK603.AA WD40 229-267 10 2.899592 3.38 Pfam 1-39 (39) Show / Hide 
Range on Protein: 229-267
Range on HMM: 1-39/39
Sequence Identity: 10% (4 aa)

KELTALSNIHNSPILFMKYNSH-YDVIVSADSTGMLEYWS
.....    |....  .... .   ...|.   | .  |.
WKCKHTF-GHTHWVTCCAWHPDMGHYLASGSRDGTIRIWD
WD40 AqueK603.AA WD40 284-322 20 9.7e-08 24.89 Pfam 1-39 (39) Show / Hide 
Range on Protein: 284-322
Range on HMM: 1-39/39
Sequence Identity: 20% (8 aa)

DTDLYEFIKHKTTPTSLVFSPN-GKLFVSTCHDRKVRVFH
 . ...|  |. . |.. ..|. |....| ..|...|.. 
WKCKHTF-GHTHWVTCCAWHPDMGHYLASGSRDGTIRIWD
WD40 AqueK603.AA WD40 283-322 16 3e-06 27.88 SMART 1-46 (46) Show / Hide 
Range on Protein: 283-322
Range on HMM: 1-46/46
Sequence Identity: 16% (8 aa)

LDTDLYEFIKHKT--TPTSLVFSPNG------KLFVSTCHDRKVRVFH
  . ...|  |.     |.. ..|.|      ....| . |...|...
T-KCVHTFKGHTGNSWVTCVCWHPDGGSDDYPNYLASGS-DGTIRIWD
Pro_isomerase AqueK603.AA Pro_isomerase 506-649 39 4.6e-70 226.16 Pfam 1-192 (192) Show / Hide 
Range on Protein: 506-649
Range on HMM: 1-192/192
Sequence Identity: 39% (76 aa)

TAVMHT-TL-GDIHLKLFPEYCPKTVENFCVHVS--NG-YYNNHIFHR-VIKS--FMIQTGD-PTG-TGT-----------GGTS--IWDGEFEDEF-HP
.....| .. |.|...|||. .|||.|||. ..   .| .|.. |||| ||.   ||||.|| ||| .||           || .  |. ..|.||| |.
YVDITTDGMGGRIVIELFPDWAPKTCENFIQLCKGKKGYFYDGTIFHRMVIPNPPFMIQGGDCPTGWDGTTPGWNYGTGRFGGCYKYIY-FPFPDEFHHF

--SLKHDRPYTLSMANAG----PNTN-GSQFFITV-VPTS---WLDNKH-TVFGRVF-RGMDVAQKISE------VKTD------PSITQLDT
   |.||.. ||.||..|    ||.| |||||||   ...   .||.|. ||||||   |||| .||..      |.||        |.   .
NKWLHHDCRGTLAMARTGEPNDPNSNNGSQFFITLDGDCPPCPHLDGKYYTVFGRVVEEGMDVVDKIEKVVENGRVPTDGRPVKNVKIKHCGV
Kinase AqueK603.AA TKL 1062-1302 20 1.2e-43 151.36 In-house 1-364 (364) Show / Hide 
Range on Protein: 1062-1302
Range on HMM: 1-364/364
Sequence Identity: 20% (76 aa)

LGRGSFAVVTVGIFRG----------LRVAVKSLHAI-----------------------IISDYNQSIFFREMSIASQVR--HPNLVQFIGATK-----
.|.|.|..|  |..||            |||| ..                         .  .. .  ||.|  | .  |  |||.|||.|. .     
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

---------VGNPLILTELM-STSLNQELQRNRLTNQQILSIAQDVALALNYLHL-----YLHLFKPQPIIHRDVSSPNILLNPSTGP---------AGY
          |.. | .|..   ||   |.      .|....|.|.|...||||      .     . ||||||  |.|||..    .         | .
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-----WHQRCRWALDIARGMNYLHSMNPKWCT----KPPIIHRDLKSKNILVDENWTNVSNYMYNPNADW

EAKVADYGTAKLQQGTS--------------------TGTVMPGNVAYAAPEARDPD----------------QHSPAMDVYSYSVLLMEMNLCCPPE--
 .|..|.|...  ....                    |     |. .. |||. . .                . |...||||. ..| |.  .|.|.  
CCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYD

----------------MTTG---------GRWQ-----QTCSVSSSDMKFLIQRGLHTRYRARPTMAQVIETL
                |  .          .||     . |.    .|| |.|.  ..  ..||.. .....|
YPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase AqueK603.AA TK 1056-1302 14 1.2e-29 95.94 In-house 1-486 (486) Show / Hide 
Range on Protein: 1056-1302
Range on HMM: 1-486/486
Sequence Identity: 14% (70 aa)

TLTEEELGRGSFA---VVTVGIFRGL---------------------------RVAVKSLHAIIISDYNQSI---------------FFREMSIASQ--V
   ...||.| |    .|  |. ||.                           .|||| |..   .. .. .               . .||.. ..   
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

RHPNLVQFIG-ATKVGN------------PLILTELMS-TS----LNQELQRNR----------------------------------------------
.|||.|...|  |....            ..|..|.|.  .    | . |...|                                              
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------LTNQQILSIAQDVALALNYLHLYLHLFKPQPIIHRDVSSPNILLNPSTG------PAGYEAKVADYG--
                               || .| | .....| .. |||     |  | ..|||.   |.|.. .          |. .|.||.|  
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFI-QNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLS

------TAKLQQGTSTGTVMPGN---------------------------VAYAAPEARD---------PDQHSPAMDVYSYSVLLMEMN-LC-CPPE--
       |.  .  .  ... .                            . . |||. .            .... ||.|. ||. |.  ..  |.   
RQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGG

MTT------------------------------GGRWQQTC--SVSS-------------SDMKFLIQRGLHTRYRARPTMAQVIETL
|.                               |.| .. .    ..              ..  |.|.  |   . |||..|. | |
MSNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase AqueK603.AA MLK 1056-1252 26 1.5e-29 99.75 In-house 1-229 (291) Show / Hide 
Range on Protein: 1056-1252
Range on HMM: 1-229/291
Sequence Identity: 26% (63 aa)

TLTEEELGRGSFAVVTVGIFRGLR-----VAVKSLHAIIISDYNQS-----IFFREMSIASQVRHPN----LVQFIGA-TKVGN-PLILTELMST-SLNQ
 ...| .| ||| .|  | .|. .     ||||  .| |. |  ..      | .|  ... ..|||     .|| |. .. ..  .|..| ..  ||. 
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYN

ELQRNR---------------LTNQQILSIAQDVALALNYLHLYLHLFKPQPIIHRDVSSPNILLNP--STGPAGYEAKVADYGTAK-LQQGTSTGTVMP
 |  .|                . ......| ..| ...|||      .|.||||||  |.|||.    .   ..  .|..| ||.. ..| ... . ..
VLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSM----APKPIIHRDLKSHNILIDEICH-DMHHGTLKICDFGTSRDWHQMCTNMMSNA

GNVAYAAPEAR---DPDQHSPAMDVYSYSVLLMEM
|..|. |||..     .. | . ||.|. |.| ||
GTYAWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEM
S_TKc AqueK603.AA S_TKc 1056-1308 20 6.7e-28 99.94 SMART 1-231 (231) Show / Hide 
Range on Protein: 1056-1308
Range on HMM: 1-231/231
Sequence Identity: 20% (54 aa)

TLTEEELGRGSFAVVTVGIFRG--LRVAVKSLHAIIISDYNQSIFFREMSIASQVRHPNLVQFIGATKVGNPLILTELMST---SLNQELQRNR------
    ...|.|.|..|  .. ..   .||.| ..           . ||..| .. .|||.|.....   ..  . .|....   .| . .....      
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-LTNQQILSIAQDVALALNYLHLYLHLFKPQPIIHRDVSSPNILLNPSTGPAGYEAKVADYGTAKLQQGTSTGTVMPGNVAYAAPEARDPDQHSP-AMDV
 ..  .. .... ...||.|.|        . |||||.   ||||.        . |..| | |..       | . |   | |||     .... . |.
PFPE-HARFYMYQICCALEYCHS-------HGIIHRDLKPENILLDE-------HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDW

YSYSVLLMEMNLCCPPEMTTGGRWQQTCSVSSSDMKFLIQRGLHTRYRARPTMAQVIE---TLKRIKFY
.|  ..| ||   .||   .  .  . .   |...| .|.. |.   . |||  .. .     |   . 
WSCGCILYEMLCGYPPFP-QMQMMFKKIG--SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK603.AA CZAK 1059-1252 30 2.4e-27 96.46 In-house 4-215 (279) Show / Hide 
Range on Protein: 1059-1252
Range on HMM: 4-215/279
Sequence Identity: 30% (66 aa)

EEELGRGSFAVVTVGIFRGLRVAVKSLHAIIISDYNQ----SIFFREMSIASQVRHPNLVQFIGATKVGN---PLILTELMS-TSLNQEL-QRNRLTNQ-
. . |.| |  |  .  ||  ||.| .| .   .        .| .| || |  .||| |||.||   ..     | .| |   || . |  .  .  | 
GQTIGQGFFGEVYKAYWRGKDVAIKIIHRNQFRNKDENKEENMFQKEVSIMSKLCHPNCVQFLGACSEDGPNHHCIVMEWMGGGSLRRLLTDHYFYHKQN

--QILSIAQDVALALNYLHLYLHLFKPQPIIHRDVSSPNILLNPSTG--------PAGYEAKVADYGTA--KLQQGTS-TGTVMPGNVAYAAPEARDPDQ
    ...| |.|   ||||     .|| ||.||| || ||||. |               .|..|.|    .  |..  | |.  | ... |||    . 
PHLQWNMAIDIARGMNYLHDN---WKPNPILHRDLSSRNILLDHSYTPKNPVVSSRQDIICKINDFGLSREMMEQPFEMTQTM--GCLCWMAPECFKGEN

HSPAMDVYSYSVLLMEM
 ..  ||||.  .| ..
YTEKVDVYSFGMILWCI
Kinase AqueK603.AA TKL-Unique 1058-1252 26 4.6e-26 88.99 In-house 1-221 (290) Show / Hide 
Range on Protein: 1058-1252
Range on HMM: 1-221/290
Sequence Identity: 26% (60 aa)

TEEELGRGSFAVVTVGIFRGLRVAVKSLHAIIISDYNQSIFF---REMSIASQVR-HPNLVQFIGATK---VGNP--LILTELMST-SLNQELQ------
  . .|.|....|  |..||  ||.|..|    .| . .. .   .| .. .  . |||.|...|...   | .|   | .| ..  ||.  |.      
FWNKIGEGGYGQVYKGKWRGYPVAIKQFHP--NEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNN

-----RNRLTNQQILSIAQDVALALNYLHLYLHLFKPQP-IIHRDVSSPNILLNPSTGPAGYEAKVADYGTAKLQQGTSTGTVM----------PGNVAY
      . |..||....|.|.|....||| .      .| |||||  |.|.|..     | . .|..| |..|..   ...|.            |.  .
NNNNNNCKLNMQQRVKMAIDIAQGMYYLHHC------EPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRW

AAPEARDP--DQHSPAMDVYSYSVLLMEM
.|||      .| |   ||||... | |.
MAPEVLRMNFCQYSEKSDVYSFGIVLWEI
Kinase AqueK603.AA STE 1057-1252 17 3.7e-19 64.37 In-house 1-261 (359) Show / Hide 
Range on Protein: 1057-1252
Range on HMM: 1-261/359
Sequence Identity: 17% (50 aa)

LTE-EELGRGSFAVVTVGIFR-----------------GLRVAVKSLH---------------AIIISDYNQSIFFREMSIASQVR--HPNLVQFIGATK
..  |..|.|.| .|  .. .                 | ..|.| ..                 .. . ..  . .|..| .. .  ||| |...|.  
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

VG--------NPLILTELMS-TSLNQELQRN---------------RLTNQQILSIAQDVALA-LNYLHLYLHLFKPQPIIHRDVSSPNILLNPSTGPAG
..        .  |  |.|.  || . ....               |.  .||  |....  . |.|||          |||||. . ||||        
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH-------IIHRDIKPANILL--------

YEAKVADYGTAKLQQG----------------------TSTGTVMPGNVAYAAPEARDP------DQHSPAMDVYSYSVLLMEM
  .| .| |...  .                       | .||       . |||  ..      ....   |..|   ...||
--VKLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP------WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEM
Pkinase_Tyr AqueK603.AA Pkinase_Tyr 1055-1252 24 1.4e-18 63.51 Pfam 1-207 (270) Show / Hide 
Range on Protein: 1055-1252
Range on HMM: 1-207/270
Sequence Identity: 24% (54 aa)

VTLTEEELGRGSFAVVTVGIFR------GLRVAVKSLHAIIISDYN--QSIFFREMSIASQV-RHPNLVQFIGATK-VGNP---LILTELMST-SLNQEL
.|.  ..||.|.| .|  |. .      .. ||||.|     .. .  .  |.||..| .|  .|||.|...|.    | |   .| .|.|   .|   |
ITFG-KKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

QRN-----RLTNQQILSIAQDVALALNYLHLYLHLFKPQPIIHRDVSSPNILLNPSTGPAGYEAKVADYGTAKLQQGTSTG-TVMP---GNVAYAAPEAR
...     .|| ...|......| ...||.        ...||||.   |.|..      .  .|..| | |.. . ...  ..       .   |||. 
RKHREDKQPLTMKDLLQMCWQIAKGMEYLES-------KNCIHRDLAARNCLVT-----ENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECI

DPDQHSPAMDVYSYSVLLMEM
     . . ||.|. ||. |.
NYGKFTTKSDVWSFGVLMWEI
Kinase AqueK603.AA Dicty4 1058-1252 28 1.6e-18 58.53 In-house 3-210 (277) Show / Hide 
Range on Protein: 1058-1252
Range on HMM: 3-210/277
Sequence Identity: 28% (62 aa)

TEEELGRGSFAVVTVGIFRGLRVAVKSL--HAIIISDYNQSIFFREMSIASQVRHPNLVQFIGA-T----KVGNPLILTELM-STSLNQELQR------N
.|...|.|||. |  |. ||  |||| |  | .  . .  . | .| .| .. ||||...| || |    . | ..| ||.| ...|   |         
IEQRIGKGSFGEVYKGTWRGKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSEQQQ

RLTNQ--QILS---IAQDVALALNYLHL--YLHLFKPQPIIHRDVSSPNILLNPSTGPAGYEAKVADYGTAK-LQQGTSTGT---VMPGNVAYAAPEARD
. . .   |..   .| |.|. .|.||            |||||  | |.|   .     . .||.| | ..  . ... ..    . | ... |||   
SIKLDWPLIKRAMRMAFDAARGMNWLHCCNPV-------IIHRDLKSHNLLVDKN-----WRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMM

PDQHSPAMDVYSYSVLLMEM
 .    . ||||.. .| |.
HQPYNEKADVYSFGIVLWEI
Kinase AqueK603.AA TK-Unique 1056-1252 20 6.4e-18 58.47 In-house 1-232 (294) Show / Hide 
Range on Protein: 1056-1252
Range on HMM: 1-232/294
Sequence Identity: 20% (51 aa)

TLTEEELGRGSFAVVTVGIFRG--------LRVAVKSLHAIIISDYNQSIFFREMSIASQVR-HPNLVQFIGATK-VG-NPLILTELMSTS-LNQELQRN
   ....|.|.|  |  | ..|         .|||| |. .  .|  .. |..| .. ...  |||.||..|..   . ...|. | .. . |   |...
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLK-DNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTC

R---------------------------LTNQQILSIAQDVALALNYLHLYLHLFKPQPIIHRDVSSPNILLNPSTGPAGYEAKVADYGTAK-------L
|                           .. .. ...| ..| ...||.  .. .     .|||... |.||.      ....|..|.| |.       .
RPAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKI-----VHRDLCARNVLLTE-----DKVCKICDFGMARDVYTNGVY

QQGTSTGTVMPGNVAYAAPEA-R--DPDQHSPAMDVYSYSVLLMEM
.  .| |...   ... |||. .  .   |..  ||.|. ||. |.
SMMCSQGRIP---IRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEI
Kinase AqueK603.AA LRRK 1056-1249 22 7.1e-18 59.8 In-house 1-272 (351) Show / Hide 
Range on Protein: 1056-1249
Range on HMM: 1-272/351
Sequence Identity: 22% (65 aa)

TLTEEELGRGSFA-VVTVGIFRG----------------------------LRVAVKSLHAI-IISDYNQ------------------------------
   ||..|||.|. .|  ...||                              ||.|... .  ..| |                               
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTID-NDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCR

--SIFFREMSIASQVRHPNLVQFIGATKVGNPLIL-TELMST-SLNQELQ---RNR-------LTNQQILSIAQDVALALNYLHLYLHLFKPQPIIHRDV
  . | .|..| |  .|||.|. .| .   .||.. .|...  .|.. |.   ...       .. . .| || ..| ...    ||| ..| |||||| 
AFREFRHEVWIMSHLNHPNIVSLKGFCI--HPLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGME----YLHSHNP-PIIHRDL

SSPNILLNPSTGP-------AGYEAKVADYGTAK----LQQG-TSTGTVMPGNVAYAAPEARDPD---QHSPAMDVYSYSVLL
 ||||||. |. .       | . ||.||.|.      .. | ... .   ||  . ||| .  .   . .   |.||. ..|
KSPNILLWSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMGVAKGCV---GNPGWMAPEIMRYNGEEEYTEKVDCYSFGMIL
Kinase AqueK603.AA Pkinase 1056-1252 23 4e-17 61.63 Pfam 1-205 (293) Show / Hide 
Range on Protein: 1056-1252
Range on HMM: 1-205/293
Sequence Identity: 23% (50 aa)

TLTEEELGRGSFAVVTVGIFRGLR--VAVKSLHAIIISDYNQSIFFR--EMSIASQVRHPNLVQFIGATK-VGNPLILTELMST-----SLNQELQ---R
  ... .|.|||..|  .. .| .  |||| .    ...  . . .|  | .|   ..||| |.....    ... . .|..       .|   ..   .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

NRL--TNQQILSIAQDVALALNYLHLYLHLFKPQPIIHRDVSSPNILLNPSTGPAGYEAKVADYGTAKL--QQGTSTGTVMPGNVAYAAPEA-RDPDQHS
...  . ... ...  .. .|.|.|          |||||. . |||.. ..|  .   |..| | ||.      |  |.  |   |.|||  |.   ..
GCFYFSEWECKFYMYQILRGLEYCHSM-------GIIHRDLKPENILID-NNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYG

PAMDVYSYSVLLMEM
|. |..|. ..| ||
PKVDMWSCGCILYEM
Kinase AqueK603.AA TyrKc 1056-1302 20 2.3e-16 41.88 SMART 1-280 (280) Show / Hide 
Range on Protein: 1056-1302
Range on HMM: 1-280/280
Sequence Identity: 20% (60 aa)

TLTEEELGRGSFAVVTVGIFRGLRVAVKSLHAIIISDYNQSIFFREMSIASQV--RHPNLVQFIGATKV--------GNPLILTELMST-SLNQELQRNR
   ...||.| | .|  |. . . ||||.|..       .  | ||..| ...  .|||.|...|.           . ..|..|.|.  .|.. |...|
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR

--LTNQQILSIAQDVALALNYLHLYLHLFKPQPIIHRDVSSPNILLNPSTGPAGYEAKVADYGTAKLQQGT-------STGTV-----MP--GNVAYAAP
  |.... ||.. ..|   .|||         ..||||    |.|..         .|..| | ..            .. ..           .   ||
PKLCMKDLLSFCWQIACGMEYLHSK-------NCIHRDLAARNCLVGENH-----TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAP

EARDPDQHSPAMDVYSYSVLLMEM-NLCCPPEMT----------------TGGRWQQTCSV-------SSSDMKFLIQRGLHTRYRARPTMAQVIETL
|. .    ... ||.|. |.. |.  .. .|                   .|.|  |  ..        ...|  ....  |     |||.....| .
ECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase AqueK603.AA HH498 1148-1252 36 4.4e-11 30.99 In-house 121-219 (284) Show / Hide 
Range on Protein: 1148-1252
Range on HMM: 121-219/284
Sequence Identity: 36% (39 aa)

QQILSIAQDVALALNYLHLYLHLFKPQPIIHRDVSSPNILLNPSTGPAGYEAKVADYGTA--KLQQGTSTGTVMPGNVAYAAPEARD-PDQHSPAMDVYS
| .. |. |||   ||||  |    ..||||||  | |||.      .   |.|||.|    . . .  . |  |||  . |||      . |   ||.|
QSKMTISVDVAHGMNYLHNSL----KHPIIHRDLNSHNILIH-----EDGHAVVADFGESRFVCDMHDDNMTKQPGNLRWMAPEVFSQCQKYSIKVDVFS

YSVLLMEM
|   . ||
YAMCIWEM
Kinase AqueK603.AA HH498 1058-1120 34 5.2e-08 21.06 In-house 3-71 (284) Show / Hide 
Range on Protein: 1058-1120
Range on HMM: 3-71/284
Sequence Identity: 34% (24 aa)

TEEELGRGSFAVVTVGIFRGLRVAVKSLHAIIISDYNQ------SIFFREMSIASQVRHPNLVQFIGAT
. |  | |||  |  | .|.  ||||   |  ..            | || || ..  ||. |||..|.
FHEKIGSGSFGKVYKGEWRNKIVAVKRYRAMAFCCKSDSYQWIVDMFCREVSIMCRLNHPCVVQFVYAC
Kinase AqueK603.AA LRRK 1292-1304 30 0.059316 2.68 In-house 339-351 (351) Show / Hide 
Range on Protein: 1292-1304
Range on HMM: 339-351/351
Sequence Identity: 30% (4 aa)

RPTMAQVIETLKR
||.. |....|. 
RPHFSQIVKRLSQ
Kinase AqueK603.AA MLK 1277-1302 23 0.128672 1.54 In-house 266-291 (291) Show / Hide 
Range on Protein: 1277-1302
Range on HMM: 266-291/291
Sequence Identity: 23% (6 aa)

MKFLIQRGLHTRYRARPTMAQVIETL
.| |...  ..  . ||...|... |
WKKLMKQCWNQDPHKRPSFRQIVQHL
Kinase AqueK603.AA Pkinase_Tyr 1292-1302 45 4.207931 0.97 Pfam 260-270 (270) Show / Hide 
Range on Protein: 1292-1302
Range on HMM: 260-270/270
Sequence Identity: 45% (5 aa)

RPTMAQVIETL
|||.....| |
RPTFSEIHEQL