Gene AqueK609 (A.queenslandica)

AqueK609

Species: A.queenslandica
Alias: AqueK609
External Links:
Annotation:

Classification

Group: TKL
Family: MLK
Subfamily: HH-C

Sequence

Name Sequence Type Origin Length Description Download
AqueK609.AA Protein None 844 None Fasta, JSON
AqueK609.kin_dom Protein Kinase Domain None 243 None Fasta, JSON

Protein domain

Protein domains of AqueK609.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kelch_1 AqueK609.AA Kelch_1 9-65 17 0.002634 15.62 Pfam 1-45 (45) Show / Hide 
Range on Protein: 9-65
Range on HMM: 1-45/45
Sequence Identity: 17% (10 aa)

GRAAHCTVSVGDSLYVWGGRQDGLPGVHDSEEKKRFTSNIQHFTPATGQWITRGTTG
 |. |. ..... .|| ||. .            ......  . | |.||    . .
PRCGHGVCVHNGKIYVIGGCDG------------QYLNSVECYDPETNQWTRCPPMP
Kelch_2 AqueK609.AA Kelch_2 9-65 19 0.061781 11.48 Pfam 1-51 (51) Show / Hide 
Range on Protein: 9-65
Range on HMM: 1-51/51
Sequence Identity: 19% (11 aa)

GRAAHCTVSVGDSLYVWGGRQDGLPGVHDSEEKKRFTSNIQHFTPATGQWITRGTTG
.|. | ....|. .||.||.        .. ..  ... |. . | | .|      .
PRYCHASCVPGGKIYVFGGYC------RHTHNNDCWSMDIWWWDPETHRWTCVPRMP
Kelch_2 AqueK609.AA Kelch_2 70-117 17 0.001203 17.98 Pfam 1-51 (51) Show / Hide 
Range on Protein: 70-117
Range on HMM: 1-51/51
Sequence Identity: 17% (9 aa)

GVREYCCTAINDQLYYFGGW---CGHDNCDHNSITQLDTVSLQWREIERID
.     .. .....| |||.    ....|....|  .|. . .|... |..
PRYCHASCVPGGKIYVFGGYCRHTHNNDCWSMDIWWWDPETHRWTCVPRMP
Kelch_1 AqueK609.AA Kelch_1 70-117 20 0.010614 13.45 Pfam 1-45 (45) Show / Hide 
Range on Protein: 70-117
Range on HMM: 1-45/45
Sequence Identity: 20% (10 aa)

GVREYCCTAINDQLYYFGGWCGHDNCDHNSITQLDTVSLQWREIERID
  . ......|...| .||..|      ||.  .|... ||...    
PRCGHGVCVHNGKIYVIGGCDG---QYLNSVECYDPETNQWTRCPPMP
Kelch_2 AqueK609.AA Kelch_2 274-307 18 0.015993 13.71 Pfam 14-51 (51) Show / Hide 
Range on Protein: 274-307
Range on HMM: 14-51/51
Sequence Identity: 18% (7 aa)

LVISGGR----DKNKDTFDDFWIFNINQHSWIKLDVPH
....||.    . | . . |.|... . |.| .. ...
IYVFGGYCRHTHNNDCWSMDIWWWDPETHRWTCVPRMP
Kelch_1 AqueK609.AA Kelch_1 274-303 13 1.589975 5.65 Pfam 14-41 (45) Show / Hide 
Range on Protein: 274-303
Range on HMM: 14-41/45
Sequence Identity: 13% (4 aa)

LVISGGRDKNKDTFDDFWIFNINQHSWIKL
. . ||.|     ........   ..| ..
IYVIGGCDG--QYLNSVECYDPETNQWTRC
Kinase AqueK609.AA TKL 603-839 19 8.8e-51 175.03 In-house 1-364 (364) Show / Hide 
Range on Protein: 603-839
Range on HMM: 1-364/364
Sequence Identity: 19% (73 aa)

LGRGSYAVVTVGIFRG----------LRVAVKSLHAIIISNYNQ-------------------------GLFSREMSIASRVRHPNLVQFIGATK-----
.|.|....|  |..||            |||| ..    .. .                            . .|. . || ||||.|||.|. .     
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

---------VGNPLILTELM-STSLYKKLQETELSNEQILSIAQDVALGLNYLHLFKP-----QPIIHRDVSSPNVLLKPCTGP---------AGYEAKV
          |.. | .|..   ||.  |.      .|....|.|.|.|.||||  .|      ||||||  |.|.|..    .         | . .|.
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-----WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKI

ADYGTAKLQQGTS--------------------TGTVMPGNVAYAAPEARDPD----------------QHSPAMDVYSYSVLLMEMTL----YS-PPEM
.|.|...  ....                    |     |. .. |||. . .                . |...||||. ..| |.      |. .|.|
CDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPYM

------------TTAEREVQSGSV---------------SWSDMKSLIQRGLNANPRARPTMAQVIESL
              .  . .   .                . .||.|.|.  ...|..||.. .... |
PMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase AqueK609.AA MLK 597-789 27 8.4e-35 118.2 In-house 1-229 (291) Show / Hide 
Range on Protein: 597-789
Range on HMM: 1-229/291
Sequence Identity: 27% (63 aa)

TLTKEELGRGSYAVVTVGIFRGLR-----VAVKSLHAII----ISNYNQGLFSREMSIASRVRHPN----LVQFIGA-TKVGN-PLILTELMST-SLYKK
 ...| .| ||. .|  | .|. .     ||||  .| |    ..   |  | .|  ......|||     .|| |. .. ..  .|..| ..  |||  
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNV

LQETE---------------LSNEQILSIAQDVALGLNYLHLFKPQPIIHRDVSSPNVLLKP-CTGPAGYEAKVADYGTAK-LQQGTSTGTVMPGNVAYA
| . .                . ......| ..| |..|||  .|.||||||  |.|.|.   |   ..  .|..| ||.. ..| ... . ..|..|. 
LHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMMSNAGTYAWM

APEAR---DPDQHSPAMDVYSYSVLLMEM
|||..     .. | . ||.|. |.| ||
APEVIQQFRCEKYSEKCDVWSWGVVLWEM
Kinase AqueK609.AA TKL-Unique 599-789 28 6.7e-32 109.84 In-house 1-221 (290) Show / Hide 
Range on Protein: 599-789
Range on HMM: 1-221/290
Sequence Identity: 28% (64 aa)

TKEELGRGSYAVVTVGIFRGLRVAVKSLHA-IIISNYNQGLFSREMSIASRVR-HPNLVQFIGATK---VGNP--LILTELMST-SLYKKLQ--------
  . .|.|.|..|  |..||  ||.|..|    .||     |..| .. .. . |||.|...|...   | .|   | .| ..  |||. |.        
FWNKIGEGGYGQVYKGKWRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNN

---ETELSNEQILSIAQDVALGLNYLHLFKPQPIIHRDVSSPNVLLKPCTGPAGYEAKVADYGTAKLQQGTSTGTVM----------PGNVAYAAPEARD
   ...|...|....|.|.|.|..|||  .|  |||||  |.|.|.      | . .|..| |..|..   ...|.            |.  ..|||   
NNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLR

P--DQHSPAMDVYSYSVLLMEM
   .| |   ||||... | |.
MNFCQYSEKSDVYSFGIVLWEI
Kinase AqueK609.AA S_TKc 597-842 18 5.9e-28 100.12 SMART 1-231 (231) Show / Hide 
Range on Protein: 597-842
Range on HMM: 1-231/231
Sequence Identity: 18% (49 aa)

TLTKEELGRGSYAVVTVGIFRG--LRVAVKSLHAIIISNYNQGLFSREMSIASRVRHPNLVQFIGATKVGNPLILTELMST---SLYKKLQETE------
    ...|.|....|  .. ..   .||.| ..           . ||..| .. .|||.|.....   ..  . .|....   .|.. ...        
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-LSNEQILSIAQDVALGLNYLHLFKPQPIIHRDVSSPNVLLKPCTGPAGYEAKVADYGTAKLQQGTSTGTVMPGNVAYAAPEARDPDQHSP-AMDVYSYS
 ..  .. .... ....|.|.|  .   |||||.   |.||         . |..| | |..       | . |   | |||     .... . |..|  
PFPE-HARFYMYQICCALEYCHSHG---IIHRDLKPENILLDE-------HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCG

VLLMEMTL----YSPPEMTTAEREVQSGSVSWSDMKSLIQRGLNANPRARPTMAQVIE------SLKRM
..| ||      ..  .| .  . .       ...|..|.. |. .|. |||  .. .      .   .
CILYEMLCGYPPFP--QMQMMFKKIG-----SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK609.AA CZAK 598-789 30 4.9e-27 95.31 In-house 1-215 (279) Show / Hide 
Range on Protein: 598-789
Range on HMM: 1-215/279
Sequence Identity: 30% (66 aa)

LTKE-ELGRGSYAVVTVGIFRGLRVAVKSLHAIIISNYNQ----GLFSREMSIASRVRHPNLVQFIGATKVGN---PLILTELMS-TSLYKKLQETELSN
|. . . |.| .  |  .  ||  ||.| .| .   |         | .| || |  .||| |||.||   ..     | .| |   || . | .     
LKFGQTIGQGFFGEVYKAYWRGKDVAIKIIHRNQFRNKDENKEENMFQKEVSIMSKLCHPNCVQFLGACSEDGPNHHCIVMEWMGGGSLRRLLTDHYFYH

EQ----ILSIAQDVALGLNYLHL-FKPQPIIHRDVSSPNVLLKPCTG--------PAGYEAKVADYGTA--KLQQGTS-TGTVMPGNVAYAAPEARDPDQ
.|     ...| |.| | ||||  .|| ||.||| || |.||                  .|..|.|    .  |..  | |.  | ... |||    . 
KQNPHLQWNMAIDIARGMNYLHDNWKPNPILHRDLSSRNILLDHSYTPKNPVVSSRQDIICKINDFGLSREMMEQPFEMTQTM--GCLCWMAPECFKGEN

HSPAMDVYSYSVLLMEM
 ..  ||||.  .| ..
YTEKVDVYSFGMILWCI
Kinase AqueK609.AA TK 597-839 13 6.1e-25 79.89 In-house 1-486 (486) Show / Hide 
Range on Protein: 597-839
Range on HMM: 1-486/486
Sequence Identity: 13% (65 aa)

TLTKEELGRGSYA---VVTVGIFRGL---------------------------RVAVKSLHAIIISNYNQGL---------------FSREMSIAS--RV
    ..||.| .    .|  |. ||.                           .|||| |..   .. .. .               . .||.. .    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

RHPNLVQFIG-ATKVGN------------PLILTELMS-TS----LYKKLQETE----------------------------------------------
.|||.|...|  |....            ..|..|.|.  .    | . |..                                                
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------LSNEQILSIAQDVALGLNYLHLFKP---QPIIHRDVSSPNVLLKPCTG------PAGYEAKVADYG---
                               |. .| | .....| |. |||  .    | ..|||.   |.|.             |. .|.||.|   
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----TAKLQQGTSTGTVMPGN---------------------------VAYAAPEARD---------PDQHSPAMDVYSYSVLLMEMTL---YSPPE-M
      |.  .  .  ... .                            . . |||. .            .... ||.|. ||. |.       ... |
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

TT---------------------------------AEREVQSGSVSW------------SDMKSLIQRGLNANPRARPTMAQVIESL
.                                   ...   .  .|             ..  |.|.  ...|. |||..|. | |
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase AqueK609.AA Dicty4 599-789 29 2.1e-23 75.09 In-house 3-210 (277) Show / Hide 
Range on Protein: 599-789
Range on HMM: 3-210/277
Sequence Identity: 29% (64 aa)

TKEELGRGSYAVVTVGIFRGLRVAVKSL--HAIIISNYNQGLFSREMSIASRVRHPNLVQFIGA-T----KVGNPLILTELM-STSLYKKLQE-------
. ...|.||.. |  |. ||  |||| |  | .  . .    | .| .| .  ||||...| || |    . | ..| ||.| ...||. |         
IEQRIGKGSFGEVYKGTWRGKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSEQQQ

-TELSNEQILS---IAQDVALGLNYLHLFKPQPIIHRDVSSPNVLLKPCTGPAGYEAKVADYGTAK-LQQGTSTGT---VMPGNVAYAAPEARDPDQHSP
 ..|. . |..   .| |.|.|.|.||   |  |||||  | | |       . . .||.| | ..  . ... ..    . | ... |||    .    
SIKLDWPLIKRAMRMAFDAARGMNWLHCCNPV-IIHRDLKSHNLLVD-----KNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPYNE

AMDVYSYSVLLMEM
. ||||.. .| |.
KADVYSFGIVLWEI
Kinase AqueK609.AA STE 598-789 17 4.1e-21 71.38 In-house 1-261 (359) Show / Hide 
Range on Protein: 598-789
Range on HMM: 1-261/359
Sequence Identity: 17% (49 aa)

LTK-EELGRGSYAVVTVGIFR-----------------GLRVAVKSLH---------------AIIISNYNQGLFSREMSIASRVR--HPNLVQFIGATK
... |..|.|.. .|  .. .                 | ..|.| ..                 .. . ..  . .|..| .. .  ||| |...|.  
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

VG--------NPLILTELMS-TSLYKKLQET-----ELS----------NEQILSIAQDVALG-LNYLHLFKPQPIIHRDVSSPNVLLKPCTGPAGYEAK
..        .  |  |.|.  || . ....     .|.           .||  |....  | |.|||  .   |||||. . |.||          .|
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH---IIHRDIKPANILL----------VK

VADYGTAKLQQG----------------------TSTGTVMPGNVAYAAPEARDP------DQHSPAMDVYSYSVLLMEM
 .| |...  .                       | .||       . |||  ..      ....   |..|   ...||
LCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP------WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEM
Kinase AqueK609.AA LRRK 597-786 22 1.3e-20 69.69 In-house 1-272 (351) Show / Hide 
Range on Protein: 597-786
Range on HMM: 1-272/351
Sequence Identity: 22% (62 aa)

TLTKEELGRGSYA-VVTVGIFRG----------------------------LRVAVKSLHAI----------------------------------IISN
    |..|||... .|  ...||                              ||.|... .                                   . .
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

YNQGLFSREMSIASRVRHPNLVQFIGATKVGNPLIL-TELMST-SLYKKLQETE----------LSNEQILSIAQDVALGLNYLHLFKPQPIIHRDVSSP
..  .| .|..| |. .|||.|. .| .   .||.. .|...  .||. |....          .|   .| || ..| |..||| ..| ||||||  ||
FR--EFRHEVWIMSHLNHPNIVSLKGFCI--HPLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNP-PIIHRDLKSP

NVLLKPCTGP-------AGYEAKVADYGTAK----LQQG-TSTGTVMPGNVAYAAPEARDPD---QHSPAMDVYSYSVLL
|.||.  . .       | . ||.||.|.      .. | ... .   ||  . ||| .  .   . .   |.||. ..|
NILLWSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMGVAKGCV---GNPGWMAPEIMRYNGEEEYTEKVDCYSFGMIL
Kinase AqueK609.AA HH498 599-789 30 1e-19 58.82 In-house 3-219 (284) Show / Hide 
Range on Protein: 599-789
Range on HMM: 3-219/284
Sequence Identity: 30% (67 aa)

TKEELGRGSYAVVTVGIFRGLRVAVKSLHAIIISNYNQ------GLFSREMSIASRVRHPNLVQFIGATKVGNP---LILTELMST-SLYKKL-------
..|  | ||.  |  | .|.  ||||   |  ..            | || || .|  ||. |||..|. .  |   .| |.  .  ||.  |       
FHEKIGSGSFGKVYKGEWRNKIVAVKRYRAMAFCCKSDSYQWIVDMFCREVSIMCRLNHPCVVQFVYAC-CDDPSQFAIVTQYCDNGSLFSILNTIPIGG

-------QETE-----LSNEQILSIAQDVALGLNYLHLFKPQPIIHRDVSSPNVLLKPCTGPAGYEAKVADYGTA--KLQQGTSTGTVMPGNVAYAAPEA
        .       ..   .. |. ||| | ||||   ..||||||  | |.|.      .   |.|||.|    . . .  . |  |||  . ||| 
AGANNNNHNQKNNYRIMDLQSKMTISVDVAHGMNYLHNSLKHPIIHRDLNSHNILIH-----EDGHAVVADFGESRFVCDMHDDNMTKQPGNLRWMAPEV

RD-PDQHSPAMDVYSYSVLLMEM
     . |   ||.||   . ||
FSQCQKYSIKVDVFSYAMCIWEM
Pkinase_Tyr AqueK609.AA Pkinase_Tyr 596-789 23 6.2e-19 64.74 Pfam 1-207 (270) Show / Hide 
Range on Protein: 596-789
Range on HMM: 1-207/270
Sequence Identity: 23% (50 aa)

VTLTKEELGRGSYAVVTVGIFR------GLRVAVKSLHAIIISNY--NQGLFSREMSIASRV-RHPNLVQFIGATK-VGNP---LILTELMST-SLYKKL
.|.  ..||.|.. .|  |. .      .. ||||.|     .     . ... |..| .   .|||.|...|.    | |   .| .|.|   .|.. |
ITFG-KKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMR-EAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

QET-----ELSNEQILSIAQDVALGLNYLHLFKPQPIIHRDVSSPNVLLKPCTGPAGYEAKVADYGTAKLQQGTSTG-TVMP---GNVAYAAPEARDPDQ
..       |. ...|......| |..||.  .   .||||.   |.|..      .  .|..| | |.. . ...  ..       .   |||.     
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKN---CIHRDLAARNCLVTE-----NNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGK

HSPAMDVYSYSVLLMEM
 . . ||.|. ||. |.
FTTKSDVWSFGVLMWEI
Kinase AqueK609.AA Pkinase 597-839 20 1.2e-18 67.03 Pfam 1-293 (293) Show / Hide 
Range on Protein: 597-839
Range on HMM: 1-293/293
Sequence Identity: 20% (62 aa)

TLTKEELGRGSYAVVTVGIFRGLR--VAVKSLHAIIISN-YNQGLFS-REMSIASRVRHPNLVQFIGATK-VGNPLILTELMST-----SLYKKLQ---E
  ... .|.||...|  .. .| .  |||| .    ..   .| ..  .| .|  |..||| |.....    ... . .|..       .|.  ..   .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

TEL--SNEQILSIAQDVALGLNYLHLFKPQPIIHRDVSSPNVLLK-PCTGPAGYEAKVADYGTAKL--QQGTSTGTVMPGNVAYAAPEA-RDPDQHSPAM
. .  | ... ...  .. ||.|.|      |||||. . |.|..  .. .|    |..| | ||.      |  |.  |   |.|||  |.   ..|. 
GCFYFSEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDA--CVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKV

DVYSYSVLLMEMTLYSPPEMTT---------------AEREVQSGSVSW---------------------SDMKSLIQRGLNANPRARPTMAQVIES--L
|..|. ..| || .  ||                    .... . .  |                     ...|..| . |. .|  ||| .|. ..  .
DMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase AqueK609.AA Dicty4-Unclassified 600-789 25 6.8e-18 57.83 In-house 4-201 (263) Show / Hide 
Range on Protein: 600-789
Range on HMM: 4-201/263
Sequence Identity: 25% (53 aa)

KEELGRGSYAVVTVGIFRGLRVAVKSLHAIIISNYNQGL--FSREMSIASRVRHPNLVQFIGATKVGNP-------LILTELM-STSLYKKLQ------E
  ..|.|  . |  |. .|  |||| .     .     .  | .|  |   . |||||.  |.    ||        | .|.| .  |           .
DQFIGKGHFSKVHKGNWKGKDVAVKKFNENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYCI--NPRSHKSTMCIVMEFMHKGNLFEVIHSKPSEQQ

TELSNEQ--ILSIAQDVALGLNYLHLFKPQPIIHRDVSSPNVLLKPCTGPAGYEAKVADYGTAKLQQGTSTGTVMPGNVAYAAPEARDPDQHSPAMDVYS
  .. .   |. .| |.| |. .||      .||||. | |.|.        . .|.|| | .     . . |   | ..  .||         . ||||
QPIKLDDTLIIKYAFDIAQGMQHLHTRN---FIHRDIKSSNILMD-----KHFNIKIADFGISRVIDFNFNMTTIAGTPKWESPECLMHESYNQKSDVYS

YSVLLMEM
| ..| |.
YAMMLYEL
Kinase AqueK609.AA TyrKc 597-839 19 6.1e-17 51.16 SMART 1-280 (280) Show / Hide 
Range on Protein: 597-839
Range on HMM: 1-280/280
Sequence Identity: 19% (58 aa)

TLTKEELGRGSYAVVTVGIFRGLRVAVKSLHAIIISNYNQGLFSREMSIASRV--RHPNLVQFIGATKV--------GNPLILTELMST-SLYKKLQETE
   ...||.| . .|  |. . . ||||.|..       .  | ||..| ...  .|||.|...|.           . ..|..|.|.  .| . |....
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR

--LSNEQILSIAQDVALGLNYLHLFKPQPIIHRDVSSPNVLLKPCTGPAGYEAKVADYGTAKLQQGT-------STGTV-----MP--GNVAYAAPEARD
  |.... ||.. ..| | .|||     ..||||    |.|..         .|..| | ..            .. ..           .   |||. .
PKLCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENH-----TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECIN

PDQHSPAMDVYSYSVLLMEM-----TLYSP-----PEMTTAEREVQSG------SV--------SWSDMKSLIQRGLNANPRARPTMAQVIESL
    ... ||.|. |.. |.     . |.       . . . . |..|                  ..| .....  ...|  |||.....| .
YGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase AqueK609.AA MLK 814-839 30 2.5e-07 21.63 In-house 266-291 (291) Show / Hide 
Range on Protein: 814-839
Range on HMM: 266-291/291
Sequence Identity: 30% (8 aa)

MKSLIQRGLNANPRARPTMAQVIESL
.|.|...  |..|. ||...|... |
WKKLMKQCWNQDPHKRPSFRQIVQHL
Kinase AqueK609.AA Dicty4 815-841 31 2.5e-05 13.92 In-house 249-277 (277) Show / Hide 
Range on Protein: 815-841
Range on HMM: 249-277/277
Sequence Identity: 31% (9 aa)

KSLIQRGLNANPRARPTMAQVIES--LKR
|.|||. .. .|  ||.....|.   |  
KHLIQWCWDHDPQHRPSFEEIIQRRILEH
Kinase AqueK609.AA HH498 816-839 33 3.2e-05 12.07 In-house 261-284 (284) Show / Hide 
Range on Protein: 816-839
Range on HMM: 261-284/284
Sequence Identity: 33% (8 aa)

SLIQRGLNANPRARPTMAQVIESL
.|||.. ...|  ||. .|..  |
NLIQMCWHPCPENRPDFDQIVTIL
Kinase AqueK609.AA LRRK 804-841 23 3.4e-05 14.33 In-house 314-351 (351) Show / Hide 
Range on Protein: 804-841
Range on HMM: 314-351/351
Sequence Identity: 23% (9 aa)

VQSGSVSWSDMKSLIQRGLNANPRARPTMAQVIESLKR
.. . . | ....|||   ...|. ||.. |... |. 
YCPPCQPWHMYQDLIQHCWQHDPKKRPHFSQIVKRLSQ
Kinase AqueK609.AA TKL-Unique 817-839 34 0.000253 11.36 In-house 268-290 (290) Show / Hide 
Range on Protein: 817-839
Range on HMM: 268-290/290
Sequence Identity: 34% (8 aa)

LIQRGLNANPRARPTMAQVIESL
|||.. . .|  ||.  ..|..|
LIQQCWHHDPSQRPSFDEIIHRL
Kinase AqueK609.AA Dicty4-Unclassified 814-839 42 0.000307 10.38 In-house 238-263 (263) Show / Hide 
Range on Protein: 814-839
Range on HMM: 238-263/263
Sequence Identity: 42% (11 aa)

MKSLIQRGLNANPRARPTMAQVIESL
.|.||   .   |. |||| |.|. |
WKKLIKWCWHNDPNKRPTMNQIIQYL
Kinase AqueK609.AA Pkinase_Tyr 811-839 24 0.078855 6.82 Pfam 242-270 (270) Show / Hide 
Range on Protein: 811-839
Range on HMM: 242-270/270
Sequence Identity: 24% (7 aa)

WSDMKSLIQRGLNANPRARPTMAQVIESL
. .. .|...  ...|  |||.....| |
PDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase AqueK609.AA CZAK 811-839 34 0.123447 1.9 In-house 251-279 (279) Show / Hide 
Range on Protein: 811-839
Range on HMM: 251-279/279
Sequence Identity: 34% (10 aa)

WSDMKSLIQRGLNANPRARPTMAQVIESL
| ..  || .  | ||  ||.  |... |
WKNLGELIEMCWNKNPDERPSFKQILQHL