Gene AqueK611 (A.queenslandica)

AqueK611

Species: A.queenslandica
Alias: AqueK611
External Links:
Annotation:

Classification

Group: TKL
Family: MLK
Subfamily: HH-C

Sequence

Name Sequence Type Origin Length Description Download
AqueK611.AA Protein None 736 None Fasta, JSON
AqueK611.kin_dom Protein Kinase Domain None 243 None Fasta, JSON

Protein domain

Protein domains of AqueK611.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kelch_2 AqueK611.AA Kelch_2 11-67 19 0.00944 14.58 Pfam 1-51 (51) Show / Hide 
Range on Protein: 11-67
Range on HMM: 1-51/51
Sequence Identity: 19% (11 aa)

GRADHRTVSVGDSLYVWAGLQGGSPRVHHSVEKRRITSNIQLFTPSTGQWITRGTTG
.|. | ....|. .||. |.        |. ..   .. |... |.| .|      .
PRYCHASCVPGGKIYVFGGYC------RHTHNNDCWSMDIWWWDPETHRWTCVPRMP
Kelch_1 AqueK611.AA Kelch_1 11-67 17 0.036191 11.54 Pfam 1-45 (45) Show / Hide 
Range on Protein: 11-67
Range on HMM: 1-45/45
Sequence Identity: 17% (10 aa)

GRADHRTVSVGDSLYVWAGLQGGSPRVHHSVEKRRITSNIQLFTPSTGQWITRGTTG
 |. |  ..... .||  |  |            ......  . |.|.||    . .
PRCGHGVCVHNGKIYVIGGCDG------------QYLNSVECYDPETNQWTRCPPMP
Kelch_1 AqueK611.AA Kelch_1 72-119 25 0.000391 18.59 Pfam 1-45 (45) Show / Hide 
Range on Protein: 72-119
Range on HMM: 1-45/45
Sequence Identity: 25% (12 aa)

GVRAYCCTAINDQLYYFGGNCGHDNCYHNSISQLDTVRLQWRELEPTD
  . ......|...| .|| .|    | ||.  .|..  ||... |  
PRCGHGVCVHNGKIYVIGGCDG---QYLNSVECYDPETNQWTRCPPMP
Kelch_2 AqueK611.AA Kelch_2 72-119 15 0.017096 13.6 Pfam 1-51 (51) Show / Hide 
Range on Protein: 72-119
Range on HMM: 1-51/51
Sequence Identity: 15% (8 aa)

GVRAYCCTAINDQLYYFGGN---CGHDNCYHNSISQLDTVRLQWRELEPTD
.     .. .....| |||     ....|....|  .|.   .|... . .
PRYCHASCVPGGKIYVFGGYCRHTHNNDCWSMDIWWWDPETHRWTCVPRMP
Kelch_2 AqueK611.AA Kelch_2 271-304 21 0.23153 9.3 Pfam 14-51 (51) Show / Hide 
Range on Protein: 271-304
Range on HMM: 14-51/51
Sequence Identity: 21% (8 aa)

LVISGGS----NKNDDTLDDCWIFNVTRHSWIKLDVPH
....||.      ||. . | |...   |.| .. ...
IYVFGGYCRHTHNNDCWSMDIWWWDPETHRWTCVPRMP
Kelch_1 AqueK611.AA Kelch_1 271-300 13 0.45449 7.6 Pfam 14-41 (45) Show / Hide 
Range on Protein: 271-300
Range on HMM: 14-41/45
Sequence Identity: 13% (4 aa)

LVISGGSNKNDDTLDDCWIFNVTRHSWIKL
. . ||..     |......... ..| ..
IYVIGGCDG--QYLNSVECYDPETNQWTRC
Kinase AqueK611.AA TKL 495-731 20 4.7e-52 179.25 In-house 1-364 (364) Show / Hide 
Range on Protein: 495-731
Range on HMM: 1-364/364
Sequence Identity: 20% (74 aa)

LGSGSYAVVTVGIFRG----------LRVAVKSLHKIIISDYNL-------------------------ALFSREMSIASQVRHPNLVQFIGATKVGS--
.|||....|  |..||            |||| ...   .  ..                           . .|. . |. ||||.|||.|. . ..  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------PLILTELM-STSLNHELCRKRLTNQQILSIAQDVALGLNYLHLFKP-----QPIIHRDVSSPNILLKPCTGP---------AGYEAKV
            . | .|..   || | |       .|....|.|.|.|.||||  .|      ||||||  |.|||..    .         | . .|.
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-----WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKI

ADYGTAKLQQGTS--------------------TGTVMPGNAAYAAPEARDPE----------------LHSPAMDVYSYSVLLMEMNLCCPPEITLAER
.|.|...  ....                    |     |. .. |||. . .                  |...||||. ..| |.  .|.|.  . ..
CDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPYM

TRQ---------SGSV-----------------------SWSDMKSLIQRGLNADPRARPTMAQVVESL
...         .. .                        . .||.|.|.  ..||..||.. .... |
PMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase AqueK611.AA MLK 489-681 28 1.3e-34 117.58 In-house 1-229 (291) Show / Hide 
Range on Protein: 489-681
Range on HMM: 1-229/291
Sequence Identity: 28% (65 aa)

TLTKEKLGSGSYAVVTVGIFRGLR-----VAVKSLHKIIISDYNLA-----LFSREMSIASQVRHPN----LVQFIGA-TKVGS-PLILTELMST-SLNH
 ...|..||||. .|  | .|. .     ||||  .  |. |   .      | .|  ... ..|||     .|| |. .. ..  .|..| ..  ||..
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYN

ELCRKR---------------LTNQQILSIAQDVALGLNYLHLFKPQPIIHRDVSSPNILLKP-CTGPAGYEAKVADYGTAK-LQQGTSTGTVMPGNAAY
 |  .|                . ......| ..| |..|||  .|.||||||  |.|||.   |   ..  .|..| ||.. ..| ... . ..|..|.
VLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMMSNAGTYAW

AAPEAR---DPELHSPAMDVYSYSVLLMEM
 |||..     |  | . ||.|. |.| ||
MAPEVIQQFRCEKYSEKCDVWSWGVVLWEM
Kinase AqueK611.AA TKL-Unique 491-681 28 3.5e-29 100.14 In-house 1-221 (290) Show / Hide 
Range on Protein: 491-681
Range on HMM: 1-221/290
Sequence Identity: 28% (63 aa)

TKEKLGSGSYAVVTVGIFRGLRVAVKSLHKIIISDYNLA---LFSREMSIASQVR-HPNLVQFIGATK---VGSP--LILTELMST-SLNHELC------
  .|.|.|.|..|  |..||  ||.|..|.   .| ..     |..| .. .  . |||.|...|...   |  |   | .| ..  ||.  |       
FWNKIGEGGYGQVYKGKWRGYPVAIKQFHP--NEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNN

-----RKRLTNQQILSIAQDVALGLNYLHLFKPQPIIHRDVSSPNILLKPCTGPAGYEAKVADYGTAKLQQGTSTGTVM----------PGNAAYAAPEA
      . |..||....|.|.|.|..|||  .|  |||||  |.|.|.      | . .|..| |..|..   ...|.            |.. ..||| 
NNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEV

RDP--ELHSPAMDVYSYSVLLMEM
     .. |   ||||... | |.
LRMNFCQYSEKSDVYSFGIVLWEI
Kinase AqueK611.AA S_TKc 489-734 19 1.8e-28 101.79 SMART 1-231 (231) Show / Hide 
Range on Protein: 489-734
Range on HMM: 1-231/231
Sequence Identity: 19% (52 aa)

TLTKEKLGSGSYAVVTVGIFRG--LRVAVKSLHKIIISDYNLALFSREMSIASQVRHPNLVQFIGATKVGSPLILTELMST---SLNHELCRKR------
    .|.|.|....|  .. ..   .||.| ..           . ||..| .. .|||.|.....   ..  . .|....   .| . .....      
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-LTNQQILSIAQDVALGLNYLHLFKPQPIIHRDVSSPNILLKPCTGPAGYEAKVADYGTAKLQQGTSTGTVMPGNAAYAAPEARDPELHSP-AMDVYSYS
 ..  .. .... ....|.|.|  .   |||||.   ||||         . |..| | |..       | . |   | |||      ... . |..|  
PFPE-HARFYMYQICCALEYCHSHG---IIHRDLKPENILLDE-------HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCG

VLLMEMNLCCP---PEITLAERTRQSGSVSWSDMKSLIQRGLNADPRARPTMAQVVE------SLKQI
..| ||   .|    . .. .. .       ...|..|.. |. ||. |||  .. .      .   .
CILYEMLCGYPPFPQMQMMFKKIG------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK611.AA TK 489-731 14 8.2e-28 89.69 In-house 1-486 (486) Show / Hide 
Range on Protein: 489-731
Range on HMM: 1-486/486
Sequence Identity: 14% (71 aa)

TLTKEKLGSGSYA---VVTVGIFRGL---------------------------RVAVKSLHKIIISDYNLAL---------------FSREMSIASQ--V
    .|||.| .    .|  |. ||.                           .|||| |..   .. .  .               . .||.. ..   
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

RHPNLVQFIG-ATKV------------GSPLILTELMS-TS----LNHELCRKR----------------------------------------------
.|||.|...|  |..            . ..|..|.|.  .    | . | ..|                                              
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------LTNQQILSIAQDVALGLNYLHLFKP---QPIIHRDVSSPNILLKPCTG------PAGYEAKVADYG---
                               || .| | .....| |. |||  .    | ..|||.   |.|.             |. .|.||.|   
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----TAKLQQGTSTGTVMPGNAA---------------------------YAAPEARD---------PELHSPAMDVYSYSVLLMEMN-LC-CPPE--I
      |.  .  .  ... .  .                           . |||. .            .... ||.|. ||. |.  ..  |.   .
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

TL------------------------------AERTRQS--GSVS-W------------SDMKSLIQRGLNADPRARPTMAQVVESL
.                                .| |.      . |             ..  |.|.  ..||. |||..|..| |
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase AqueK611.AA Dicty4 491-681 29 2.1e-27 88.59 In-house 3-210 (277) Show / Hide 
Range on Protein: 491-681
Range on HMM: 3-210/277
Sequence Identity: 29% (63 aa)

TKEKLGSGSYAVVTVGIFRGLRVAVKSL--HKIIISDYNLALFSREMSIASQVRHPNLVQFIGA-T----KVGSPLILTELM-STSLNHELCRK------
. ...|.||.. |  |. ||  |||| |  |..  . . |  | .| .| .. ||||...| || |    . |...| ||.| ...| ..| ..      
IEQRIGKGSFGEVYKGTWRGKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNL-YSLLHDKPSEQQ

-RLTNQ--QILS---IAQDVALGLNYLHLFKPQPIIHRDVSSPNILLKPCTGPAGYEAKVADYGTAK-LQQGTSTGT---VMPGNAAYAAPEARDPELHS
 . . .   |..   .| |.|.|.|.||   |  |||||  | |.|       . . .||.| | ..  . ... ..    . | ... |||    .   
QSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPV-IIHRDLKSHNLLVD-----KNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPYN

PAMDVYSYSVLLMEM
 . ||||.. .| |.
EKADVYSFGIVLWEI
Kinase AqueK611.AA STE 490-658 19 1.8e-21 72.65 In-house 1-232 (359) Show / Hide 
Range on Protein: 490-658
Range on HMM: 1-232/359
Sequence Identity: 19% (48 aa)

LTK-EKLGSGSYAVVTVGIFR-----------------GLRVAVKSLHKIIIS---------------DYNLALFSREMSIASQVR--HPNLVQFIGATK
... ||.|.|.. .|  .. .                 | ..|.| ...   .               . ..  . .|..| .. .  ||| |...|.  
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

VG--------SPLILTELMS-TSLNHELCRK---------------RLTNQQILSIAQDVALG-LNYLHLFKPQPIIHRDVSSPNILLKPCTGPAGYEAK
..        .  |  |.|.  ||   . .|               |.  .||  |....  | |.|||  .   |||||. . ||||          .|
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH---IIHRDIKPANILL----------VK

VADYGTAKLQQG----------------------TSTGTVMPGNAAYAAPE
 .| |...  .                       | .||       . |||
LCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP------WMAPE
Kinase AqueK611.AA CZAK 584-681 33 3.2e-19 66.56 In-house 108-215 (279) Show / Hide 
Range on Protein: 584-681
Range on HMM: 108-215/279
Sequence Identity: 33% (37 aa)

LSIAQDVALGLNYLHL-FKPQPIIHRDVSSPNILLKPCTG--------PAGYEAKVADYGTA--KLQQGTS-TGTVMPGNAAYAAPEARDPELHSPAMDV
...| |.| | ||||  .|| ||.||| || ||||                  .|..|.|    .  |..  | |.  |  .. |||    |. ..  ||
WNMAIDIARGMNYLHDNWKPNPILHRDLSSRNILLDHSYTPKNPVVSSRQDIICKINDFGLSREMMEQPFEMTQTM--GCLCWMAPECFKGENYTEKVDV

YSYSVLLMEM
||.  .| ..
YSFGMILWCI
Pkinase_Tyr AqueK611.AA Pkinase_Tyr 488-634 27 3.7e-19 65.49 Pfam 1-156 (270) Show / Hide 
Range on Protein: 488-634
Range on HMM: 1-156/270
Sequence Identity: 27% (46 aa)

VTLTKEKLGSGSYAVVTVGIFR------GLRVAVKSLHKIIISDYN--LALFSREMSIASQV-RHPNLVQFIGATK-VGSP---LILTELMST-SLNHEL
.|.  .|||.|.. .|  |. .      .. ||||.| |   .. .  .. | ||..| .|  .|||.|...|.    | |   .| .|.|   .| . |
ITFG-KKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

CRK-----RLTNQQILSIAQDVALGLNYLHLFKPQPIIHRDVSSPNILLKPCTGPAGYEAKVADYG
 ..     .|| ...|......| |..||.  .   .||||.   |.|..      .  .|..| |
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKN---CIHRDLAARNCLVTE-----NNVVKICDFG
Kinase AqueK611.AA LRRK 489-678 22 7.5e-19 63.32 In-house 1-272 (351) Show / Hide 
Range on Protein: 489-678
Range on HMM: 1-272/351
Sequence Identity: 22% (62 aa)

TLTKEKLGSGSYA-VVTVGIFRG----------------------------LRVAVKSLHK--------------------------------IIISDYN
    |..|.|... .|  ...||                              ||.|....                                .. .  .
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

LALFSREMSIASQVRHPNLVQFIGATKVGSPLIL-TELMST-SLNHELC---RKR-------LTNQQILSIAQDVALGLNYLHLFKPQPIIHRDVSSPNI
. .| .|..| |  .|||.|. .| .   .||.. .|...  .|.| |    . .       .. . .| || ..| |..||| ..| ||||||  ||||
FREFRHEVWIMSHLNHPNIVSLKGFCI--HPLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNP-PIIHRDLKSPNI

LLKPCTGP-------AGYEAKVADYGTAK----LQQG-TSTGTVMPGNAAYAAPEARD---PELHSPAMDVYSYSVLL
||.  . .       | . ||.||.|.      .. | ... .   ||  . ||| .     |  .   |.||. ..|
LLWSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMGVAKGCV---GNPGWMAPEIMRYNGEEEYTEKVDCYSFGMIL
Kinase AqueK611.AA Dicty4-Unclassified 488-681 25 5.3e-18 58.21 In-house 1-201 (263) Show / Hide 
Range on Protein: 488-681
Range on HMM: 1-201/263
Sequence Identity: 25% (54 aa)

VTLTKEKLGSGSYAVVTVGIFRGLRVAVKSLHKIIISDY--NLALFSREMSIASQVRHPNLVQFIGATKVGSP-------LILTELMSTSLNHELCR---
.   .. .| |  . |  |. .|  |||| .     .     .  | .|  |   . |||||.  |.     |        | .|.|      |.     
IQIDQF-IGKGHFSKVHKGNWKGKDVAVKKFNENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYCI--NPRSHKSTMCIVMEFMHKGNLFEVIHSKP

----KRLTNQQ--ILSIAQDVALGLNYLHLFKPQPIIHRDVSSPNILLKPCTGPAGYEAKVADYGTAKLQQGTSTGTVMPGNAAYAAPEARDPELHSPAM
    . .      |. .| |.| |. .||      .||||. | |||.        . .|.|| | .     . . |   |  .  .||    |    . 
SEQQQPIKLDDTLIIKYAFDIAQGMQHLHTRN---FIHRDIKSSNILMD-----KHFNIKIADFGISRVIDFNFNMTTIAGTPKWESPECLMHESYNQKS

DVYSYSVLLMEM
||||| ..| |.
DVYSYAMMLYEL
Kinase AqueK611.AA TyrKc 489-731 20 2.5e-16 41.35 SMART 1-280 (280) Show / Hide 
Range on Protein: 489-731
Range on HMM: 1-280/280
Sequence Identity: 20% (60 aa)

TLTKEKLGSGSYAVVTVGIFRGLRVAVKSLHKIIISDYNLALFSREMSIASQV--RHPNLVQFIGATKV--------GSPLILTELMST-SLNHELCRKR
   ..|||.| . .|  |. . . ||||.|..       .. | ||..| ...  .|||.|...|.           . ..|..|.|.  .|.. | ..|
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR

--LTNQQILSIAQDVALGLNYLHLFKPQPIIHRDVSSPNILLKPCTGPAGYEAKVADYGTAKLQQGT-------STGTV-----MP--GNAAYAAPEARD
  |.... ||.. ..| | .|||     ..||||    |.|..         .|..| | ..            .. ..               |||. .
PKLCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENH-----TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECIN

PELHSPAMDVYSYSVLLMEM-NLCCPPEIT--------------LAERTRQSGSVS---------WSDMKSLIQRGLNADPRARPTMAQVVESL
    ... ||.|. |.. |.  .. .|                 . .. |     .          ..| .....  ..||  |||.....| .
YGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase AqueK611.AA Pkinase 489-681 25 1.1e-14 52.96 Pfam 1-205 (293) Show / Hide 
Range on Protein: 489-681
Range on HMM: 1-205/293
Sequence Identity: 25% (53 aa)

TLTKEKLGSGSYAVVTVGIFRGLR--VAVKSLHKIIISDYNLALFSR--EMSIASQVRHPNLVQFIGATK-VGSPLILTELMST-----SLNHELC---R
  ...|.||||...|  .. .| .  |||| . |  ...  .    |  | .|   ..||| |.....    ... . .|..       .| . .    .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

KRL--TNQQILSIAQDVALGLNYLHLFKPQPIIHRDVSSPNILLK-PCTGPAGYEAKVADYGTAKL--QQGTSTGTVMPGNAAYAAPEA-RDPELHSPAM
...  . ... ...  .. ||.|.|      |||||. . |||..  .. .|    |..| | ||.      |  |.  |   |.|||  |. . ..|. 
GCFYFSEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDA--CVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKV

DVYSYSVLLMEM
|..|. ..| ||
DMWSCGCILYEM
Kinase AqueK611.AA HH498 581-681 37 2.4e-13 38.25 In-house 121-219 (284) Show / Hide 
Range on Protein: 581-681
Range on HMM: 121-219/284
Sequence Identity: 37% (39 aa)

QQILSIAQDVALGLNYLHLFKPQPIIHRDVSSPNILLKPCTGPAGYEAKVADYGTA--KLQQGTSTGTVMPGNAAYAAPEARD-PELHSPAMDVYSYSVL
| .. |. ||| | ||||   ..||||||  | |||.      .   |.|||.|    . . .  . |  |||  . |||        |   ||.||   
QSKMTISVDVAHGMNYLHNSLKHPIIHRDLNSHNILIH-----EDGHAVVADFGESRFVCDMHDDNMTKQPGNLRWMAPEVFSQCQKYSIKVDVFSYAMC

LMEM
. ||
IWEM
Kinase AqueK611.AA CZAK 490-552 33 4.2e-08 25.67 In-house 1-68 (279) Show / Hide 
Range on Protein: 490-552
Range on HMM: 1-68/279
Sequence Identity: 33% (23 aa)

LTKEK-LGSGSYAVVTVGIFRGLRVAVKSLHKIIISDYNL----ALFSREMSIASQVRHPNLVQFIGA
|. ..  | | .  |  .  ||  ||.| .|..   .         | .| || |  .||| |||.||
LKFGQTIGQGFFGEVYKAYWRGKDVAIKIIHRNQFRNKDENKEENMFQKEVSIMSKLCHPNCVQFLGA
Kinase AqueK611.AA MLK 706-731 38 9.2e-08 23.15 In-house 266-291 (291) Show / Hide 
Range on Protein: 706-731
Range on HMM: 266-291/291
Sequence Identity: 38% (10 aa)

MKSLIQRGLNADPRARPTMAQVVESL
.|.|...  |.||. ||...|.|. |
WKKLMKQCWNQDPHKRPSFRQIVQHL
Kinase AqueK611.AA LRRK 703-733 38 6.2e-07 20.54 In-house 321-351 (351) Show / Hide 
Range on Protein: 703-733
Range on HMM: 321-351/351
Sequence Identity: 38% (12 aa)

WSDMKSLIQRGLNADPRARPTMAQVVESLKQ
| ....|||   ..||. ||.. |.|. |.|
WHMYQDLIQHCWQHDPKKRPHFSQIVKRLSQ
Kinase AqueK611.AA HH498 491-553 34 7.8e-07 17.27 In-house 3-71 (284) Show / Hide 
Range on Protein: 491-553
Range on HMM: 3-71/284
Sequence Identity: 34% (24 aa)

TKEKLGSGSYAVVTVGIFRGLRVAVKSLHKIIISDYNL------ALFSREMSIASQVRHPNLVQFIGAT
..|| ||||.  |  | .|.  ||||      ..            | || || ..  ||. |||..|.
FHEKIGSGSFGKVYKGEWRNKIVAVKRYRAMAFCCKSDSYQWIVDMFCREVSIMCRLNHPCVVQFVYAC
Kinase AqueK611.AA Dicty4 707-733 31 1.7e-05 14.5 In-house 249-277 (277) Show / Hide 
Range on Protein: 707-733
Range on HMM: 249-277/277
Sequence Identity: 31% (9 aa)

KSLIQRGLNADPRARPTMAQVVES--LKQ
|.|||. .. ||  ||.......   |  
KHLIQWCWDHDPQHRPSFEEIIQRRILEH
Kinase AqueK611.AA HH498 708-731 37 7.2e-05 10.94 In-house 261-284 (284) Show / Hide 
Range on Protein: 708-731
Range on HMM: 261-284/284
Sequence Identity: 37% (9 aa)

SLIQRGLNADPRARPTMAQVVESL
.|||.. .. |  ||. .|.|  |
NLIQMCWHPCPENRPDFDQIVTIL
Kinase AqueK611.AA Dicty4-Unclassified 706-731 42 0.000157 11.39 In-house 238-263 (263) Show / Hide 
Range on Protein: 706-731
Range on HMM: 238-263/263
Sequence Identity: 42% (11 aa)

MKSLIQRGLNADPRARPTMAQVVESL
.|.||   .  ||. |||| |... |
WKKLIKWCWHNDPNKRPTMNQIIQYL
Kinase AqueK611.AA TKL-Unique 709-731 34 0.000338 10.91 In-house 268-290 (290) Show / Hide 
Range on Protein: 709-731
Range on HMM: 268-290/290
Sequence Identity: 34% (8 aa)

LIQRGLNADPRARPTMAQVVESL
|||.. . ||  ||.  .....|
LIQQCWHHDPSQRPSFDEIIHRL
Kinase AqueK611.AA Pkinase_Tyr 703-731 27 0.017432 9.04 Pfam 242-270 (270) Show / Hide 
Range on Protein: 703-731
Range on HMM: 242-270/270
Sequence Identity: 27% (8 aa)

WSDMKSLIQRGLNADPRARPTMAQVVESL
. .. .|...  ..||  |||.....| |
PDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase AqueK611.AA Pkinase 700-731 22 0.077374 7.58 Pfam 244-293 (293) Show / Hide 
Range on Protein: 700-731
Range on HMM: 244-293/293
Sequence Identity: 22% (11 aa)

SVSW----------------SDMKSLIQRGLNADPRARPTMAQVVES--L
|.|.                ...|..| . |. ||  ||| .|....  .
SISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase AqueK611.AA Pkinase_Tyr 670-681 50 7.917708 0.04 Pfam 196-207 (270) Show / Hide 
Range on Protein: 670-681
Range on HMM: 196-207/270
Sequence Identity: 50% (6 aa)

DVYSYSVLLMEM
||.|. ||. |.
DVWSFGVLMWEI