Gene AqueK612 (A.queenslandica)

AqueK612

Species: A.queenslandica
Alias: AqueK612
External Links:
Annotation:

Classification

Group: TKL
Family: MLK
Subfamily: HH-C

Sequence

Name Sequence Type Origin Length Description Download
AqueK612.AA Protein None 893 None Fasta, JSON
AqueK612.kin_dom Protein Kinase Domain None 243 None Fasta, JSON

Protein domain

Protein domains of AqueK612.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kelch_1 AqueK612.AA Kelch_1 83-130 22 0.000157 20.01 Pfam 1-45 (45) Show / Hide 
Range on Protein: 83-130
Range on HMM: 1-45/45
Sequence Identity: 22% (11 aa)

GIIAYCCTAIDDLLYYFGGYCGHHSCYHNSISQLDTASLQWRELEPTD
    ..........| .||..|    | ||.  .|. . ||... |  
PRCGHGVCVHNGKIYVIGGCDG---QYLNSVECYDPETNQWTRCPPMP
Kelch_1 AqueK612.AA Kelch_1 286-316 16 1.500685 5.74 Pfam 13-41 (45) Show / Hide 
Range on Protein: 286-316
Range on HMM: 13-41/45
Sequence Identity: 16% (5 aa)

RLMISGGRDKNYDTLDDCWILNITQHSWIKL
.. . ||.|     |....... . ..| ..
KIYVIGGCDG--QYLNSVECYDPETNQWTRC
Kinase AqueK612.AA TKL 652-888 20 2.4e-48 166.95 In-house 1-364 (364) Show / Hide 
Range on Protein: 652-888
Range on HMM: 1-364/364
Sequence Identity: 20% (76 aa)

LGRGSYAVVTVGNFRG----------LRVAVKSLHNMIISDYNL-------------------------GIFTREMTIASQVRHPNLVQFIGATK-----
.|.|....|  |..||            |||| .. .  .  ..                           . .|. . |. ||||.|||.|. .     
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

---------VGHPLILTELM-STSLNHELRKNRLTNQQILSIAQDVALGLNYLHLFKP-----QPIIHRDISSPNVLLKPCTGP---------AGYEAKV
          |.. | .|..   || | |       .|....|.|.|.|.||||  .|      ||||||. |.|.|..    .         | . .|.
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-----WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKI

ADYGTAKVVQAES--------------------TGTVMPGNPAYAAPEAPIPD----------------RHSPAMDVYSYSVLLMELNLLCPPE--MTT-
.|.|...... ..                    |     |.|.. |||.   .                  |...||||. ..| |.   |.|.  .   
CDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPYM

------------VERAQQSARVSWS-----------------HMKSLIQRGLNTDPADRPTMAEVIRSL
            . ... . |                     .||.|.|.  ..|| .||.. |..  |
PMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase AqueK612.AA MLK 646-838 26 7.2e-35 118.43 In-house 1-229 (291) Show / Hide 
Range on Protein: 646-838
Range on HMM: 1-229/291
Sequence Identity: 26% (60 aa)

TLTKEELGRGSYAVVTVGNFRGLR-----VAVKSLHNMIISDYNL-----GIFTREMTIASQVRHPN----LVQFIGA-TKVGH-PLILTELMST-SLNH
 ...| .| ||. .|  |..|. .     ||||  . .|. |          | .|  ... ..|||     .|| |. .. ..  .|..| ..  ||..
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYN

ELRKNR---------------LTNQQILSIAQDVALGLNYLHLFKPQPIIHRDISSPNVLLKP-CTGPAGYEAKVADYGTAKVVQAE-STGTVMPGNPAY
 |. .|                . ......| ..| |..|||  .|.||||||. |.|.|.   |   ..  .|..| ||.. ..   .. . ..|..|.
VLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMMSNAGTYAW

AAPEAP---IPDRHSPAMDVYSYSVLLMEL
 |||.      .. | . ||.|. |.| |.
MAPEVIQQFRCEKYSEKCDVWSWGVVLWEM
Kinase AqueK612.AA TK 646-888 14 4.8e-34 110.96 In-house 1-486 (486) Show / Hide 
Range on Protein: 646-888
Range on HMM: 1-486/486
Sequence Identity: 14% (71 aa)

TLTKEELGRGSYA---VVTVGNFRGL---------------------------RVAVKSLH---NMIISDYNLGIFT---------REMTIASQVR----
    ..||.| .    .|  |  ||.                           .|||| |.   .|   .  . ...         .|. .... .    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HPNLVQFIG-ATKV------------GHPLILTELMS-TS----LNHELRKNR----------------------------------------------
 |||.|...|  |..            ....|..|.|.  .    | . |||.|                                              
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------LTNQQILSIAQDVALGLNYLHLFKP---QPIIHRDISSPNVLLKPCTG------PAGYEAKVADYG---
                               || .| | .....| |. |||  .    | ..|||.   |.|.             |. .|.||.|   
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----TAKVVQAESTGTVMPGNPA---------------------------YAAPEAPI---------PDRHSPAMDVYSYSVLLMELNLLC--PPE--M
      |. .. ..  ... .  .                           . |||.             ..... ||.|. ||. |.  ..  |.   |
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

TT------------VERAQQ------------SARVSWS--HMKS-------------------LIQRGLNTDPADRPTMAEVIRSL
.             .|. ..              |         .                   |.|.  . ||.||||.... . |
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase AqueK612.AA S_TKc 646-889 20 2.1e-29 104.91 SMART 1-231 (231) Show / Hide 
Range on Protein: 646-889
Range on HMM: 1-231/231
Sequence Identity: 20% (54 aa)

TLTKEELGRGSYAVVTVGNFRG--LRVAVKSLHNMIISDYNLGIFTREMTIASQVRHPNLVQFIGATKVGHPLILTELMST---SLNHELRKNR------
    ...|.|....|  .  ..   .||.| ..           . ||. | .. .|||.|.....   .|  . .|....   .| . ..|..      
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-LTNQQILSIAQDVALGLNYLHLFKPQPIIHRDISSPNVLLKPCTGPAGYEAKVADYGTAKVVQAESTGTVMPGNPAYAAPEAPIPDRHSP-AMDVYSYS
 ..  .. .... ....|.|.|  .   |||||.   |.||         . |..| | |...      | . | | | |||      ... . |..|  
PFPE-HARFYMYQICCALEYCHSHG---IIHRDLKPENILLDE-------HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCG

VLLMELNLLCPPEMTTVERAQQSARVSWSHMKSLIQRGLNTDPADRPTMAEVIR--------SLK
..| |.   .||   ....  .  .   . .|..|.. |. ||..|||  |. .           
CILYEMLCGYPPFP-QMQMMFKKIG--SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK612.AA Dicty4 648-838 30 1.6e-28 92.36 In-house 3-210 (277) Show / Hide 
Range on Protein: 648-838
Range on HMM: 3-210/277
Sequence Identity: 30% (65 aa)

TKEELGRGSYAVVTVGNFRGLRVAVKSL--HNMIISDYNLGIFTREMTIASQVRHPNLVQFIGA-T----KVGHPLILTELM-STSLNHELRK------N
. ...|.||.. |  |. ||  |||| |  ||   . . |  | .| .| .. ||||...| || |    . | ..| ||.| ...|   |..       
IEQRIGKGSFGEVYKGTWRGKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSEQQQ

RLTNQ--QILS---IAQDVALGLNYLHLFKPQPIIHRDISSPNVLLKPCTGPAGYEAKVADYGTAKVVQAESTGTV----MPGNPAYAAPEAPIPDRHSP
. . .   |..   .| |.|.|.|.||   |  |||||. | | |       . . .||.| | ... . ... .     . | |.. |||    ..   
SIKLDWPLIKRAMRMAFDAARGMNWLHCCNPV-IIHRDLKSHNLLVD-----KNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPYNE

AMDVYSYSVLLMEL
. ||||.. .| |.
KADVYSFGIVLWEI
Kinase AqueK612.AA TKL-Unique 648-838 28 3.1e-28 96.75 In-house 1-221 (290) Show / Hide 
Range on Protein: 648-838
Range on HMM: 1-221/290
Sequence Identity: 28% (63 aa)

TKEELGRGSYAVVTVGNFRGLRVAVKSLH-NMIISDYNLGIFTREMTIASQVR-HPNLVQFIGATK---VGHP--LILTELMST-SLNHELR--------
  . .|.|.|..|  | .||  ||.|..| |  .|   .  | .| .. .  . |||.|...|...   |  |   | .| ..  ||.  |         
FWNKIGEGGYGQVYKGKWRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNN

---KNRLTNQQILSIAQDVALGLNYLHLFKPQPIIHRDISSPNVLLKPCTGPAGYEAKVADYGTAKVVQAESTGTVM----------PGNPAYAAPEAPI
   .. |..||....|.|.|.|..|||  .|  |||||. |.|.|.      | . .|..| |..|.   ....|.            |.. ..|||   
NNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLR

P--DRHSPAMDVYSYSVLLMEL
   .  |   ||||... | |.
MNFCQYSEKSDVYSFGIVLWEI
Kinase AqueK612.AA CZAK 647-838 30 3.5e-24 84.81 In-house 1-215 (279) Show / Hide 
Range on Protein: 647-838
Range on HMM: 1-215/279
Sequence Identity: 30% (66 aa)

LTKE-ELGRGSYAVVTVGNFRGLRVAVKSLHNMIISDYNL----GIFTREMTIASQVRHPNLVQFIGA-TKVG--HPLILTELMS-TSLNHELRKNRLTN
|. . . |.| .  |  .  ||  ||.| .|     .        .| .|  | |  .||| |||.|| .  |  |  | .| |   ||   |       
LKFGQTIGQGFFGEVYKAYWRGKDVAIKIIHRNQFRNKDENKEENMFQKEVSIMSKLCHPNCVQFLGACSEDGPNHHCIVMEWMGGGSLRRLLTDHYFYH

QQ----ILSIAQDVALGLNYLHL-FKPQPIIHRDISSPNVLLKPCTG--------PAGYEAKVADYGTA---KVVQAESTGTVMPGNPAYAAPEAPIPDR
.|     ...| |.| | ||||  .|| ||.||| || |.||                  .|..|.|     .    | | |.  |  .. |||  . . 
KQNPHLQWNMAIDIARGMNYLHDNWKPNPILHRDLSSRNILLDHSYTPKNPVVSSRQDIICKINDFGLSREMMEQPFEMTQTM--GCLCWMAPECFKGEN

HSPAMDVYSYSVLLMEL
 ..  ||||.  .| ..
YTEKVDVYSFGMILWCI
Kinase AqueK612.AA STE 647-815 18 1.5e-21 72.96 In-house 1-232 (359) Show / Hide 
Range on Protein: 647-815
Range on HMM: 1-232/359
Sequence Identity: 18% (45 aa)

LTK-EELGRGSYAVVTVG-----------------NFRGLRVAVKSLH---------------NMIISDYNLGIFTREMTIASQVR--HPNLVQFIGATK
... |..|.|.. .|  .                 .  | ..|.| ..               .... . ..  . .|. | .. .  ||| |...|.  
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

VG--------HPLILTELMS-TSLNHELRKN---------------RLTNQQILSIAQDVALG-LNYLHLFKPQPIIHRDISSPNVLLKPCTGPAGYEAK
..        .  |  |.|.  ||   ....               |.  .||  |....  | |.|||  .   |||||| . |.||          .|
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH---IIHRDIKPANILL----------VK

VADYGTAKVVQAESTGT-----------------VMPGNPAYAAPE
 .| |... .. ....                   . | | . |||
LCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPE
Kinase AqueK612.AA DRK 653-838 35 1.2e-20 66.73 In-house 8-195 (258) Show / Hide 
Range on Protein: 653-838
Range on HMM: 8-195/258
Sequence Identity: 35% (70 aa)

GRGSYAVVTVGNFRGLRVAVKSLHNMIISDYN-LGIFTREMTIASQVRHPNLVQFIGA-TKVGHPLILTELMST-SLNHELRKNRLTNQ--QILSIAQDV
|||.|. |  |  ||  |||| | |  | | | |  | || .. .| |||| .||.|. .    ..| .| |.  ||   |    .  .   ..... |.
GRGNYGEVFRGTWRGTQVAVKMLFNHNINDENFLNEFHREINLMCQLRHPNICQFMGTCNNPPDICICMEYMPRGSLYNILHDESIEMDWPLMKQMMFDC

ALGLNYLHLFKPQPIIHRDISSPNVLLKPCTGPAGYEAKVADYGTAK----VVQAESTGTVMPGNPAYAAPEAPIPDRHSPAMDVYSYSVLLMEL
| |..|||   |  |||||  | | |         .  ||||.| .     . |   . | | | |   |||    .|     ||||. . | |.
AKGMIYLHCCNPI-IIHRDLKSHNLLVD-----EHWQVKVADFGLSTRFKKHKQHKFAMT-MCGTPCWTAPEVLRNQRYTEKADVYSFAIVLWEC
Kinase AqueK612.AA LRRK 646-815 21 2.6e-20 68.53 In-house 1-249 (351) Show / Hide 
Range on Protein: 646-815
Range on HMM: 1-249/351
Sequence Identity: 21% (55 aa)

TLTKEELGRGSYA-VVTVGNFRG----------------------------LRVAVKSLHN----------------------------------MIISD
    |..|||... .|  ...||                              ||.|...                                   . .  
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

YNLGIFTREMTIASQVRHPNLVQFIGATKVGHPLILTELMST-SLNHELRKNR----------LTNQQILSIAQDVALGLNYLHLFKPQPIIHRDISSPN
...  | .|..| |  .|||.|. .| .   .. . .|...  .|.| |....          .. . .| || ..| |..||| ..| ||||||  |||
FRE--FRHEVWIMSHLNHPNIVSLKGFC-IHPLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNP-PIIHRDLKSPN

VLLKPCTGP-------AGYEAKVADYGTAK---VVQAESTGTVMPGNPAYAAPE
.||.  . .       | . ||.||.|.     ... . . ..  ||| . |||
ILLWSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMGVAKGCV-GNPGWMAPE
Kinase AqueK612.AA Dicty4-Unclassified 649-838 27 2.5e-19 62.83 In-house 4-201 (263) Show / Hide 
Range on Protein: 649-838
Range on HMM: 4-201/263
Sequence Identity: 27% (57 aa)

KEELGRGSYAVVTVGNFRGLRVAVKSLHNMIISDY--NLGIFTREMTIASQVRHPNLVQFIGATKVGHP-------LILTELMSTSLNHELRK-------
  ..|.|  . |  || .|  |||| .     .     .  | .|  |   . |||||.  |.     |        | .|.|      |.         
DQFIGKGHFSKVHKGNWKGKDVAVKKFNENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYCI--NPRSHKSTMCIVMEFMHKGNLFEVIHSKPSEQQ

NRLTNQQ--ILSIAQDVALGLNYLHLFKPQPIIHRDISSPNVLLKPCTGPAGYEAKVADYGTAKVVQAESTGTVMPGNPAYAAPEAPIPDRHSPAMDVYS
  .      |. .| |.| |. .||      .||||| | |.|.        . .|.|| | . |.    . |   | |.  .||         . ||||
QPIKLDDTLIIKYAFDIAQGMQHLHTRN---FIHRDIKSSNILMD-----KHFNIKIADFGISRVIDFNFNMTTIAGTPKWESPECLMHESYNQKSDVYS

YSVLLMEL
| ..| ||
YAMMLYEL
Pkinase_Tyr AqueK612.AA Pkinase_Tyr 645-838 25 5.2e-19 65.0 Pfam 1-207 (270) Show / Hide 
Range on Protein: 645-838
Range on HMM: 1-207/270
Sequence Identity: 25% (56 aa)

VTLTKEELGRGSYAVVTVGNFR------GLRVAVKSLHNMIISDYN--LGIFTREMTIASQV-RHPNLVQFIGATK-VGHP---LILTELMST-SLNHEL
.|.  ..||.|.. .|  |  .      .. ||||.| .   .. .  .  | ||. | .|  .|||.|...|.    | |   .| .|.|   .| . |
ITFG-KKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

RKN-----RLTNQQILSIAQDVALGLNYLHLFKPQPIIHRDISSPNVLLKPCTGPAGYEAKVADYGTAKVVQAESTG-TVMP---GNPAYAAPEAPIPDR
||.     .|| ...|......| |..||.  .   .||||.   |.|..      .  .|..| | |. .. ...  ..           |||.    .
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKN---CIHRDLAARNCLVTE-----NNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGK

HSPAMDVYSYSVLLMEL
 . . ||.|. ||. |.
FTTKSDVWSFGVLMWEI
Kinase AqueK612.AA TyrKc 646-888 22 7.4e-16 33.71 SMART 1-280 (280) Show / Hide 
Range on Protein: 646-888
Range on HMM: 1-280/280
Sequence Identity: 22% (66 aa)

TLTKEELGRGSYAVVTVGNFRGLRVAVKSLHNMIISDYNLGIFTREMTIASQV--RHPNLVQFIGATKV--------GHPLILTELMST-SLNHELRKNR
   ...||.| . .|  |  . . ||||.|..       .  | ||. | ...  .|||.|...|.           . ..|..|.|.  .|.. |||.|
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR

--LTNQQILSIAQDVALGLNYLHLFKPQPIIHRDISSPNVLLKPCTGPAGYEAKVADYGTAKVVQAE-------STGTVM---PGNP----AYAAPEAPI
  |.... ||.. ..| | .|||     ..||||.   |.|..         .|..| | .. .  .       .. ...    |.        |||.  
PKLCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENH-----TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECIN

PDRHSPAMDVYSYSVLLMELNLLC---PPE-----MTTVE---------RAQQSARV-------SWSHMKSLIQRGLNTDPADRPTMAEVIRSL
  . ... ||.|. |.. |.  ..   .|.     |.  |         |  | . .         . | .....  . ||.||||..|... .
YGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase AqueK612.AA Pkinase 646-838 22 1.1e-14 52.97 Pfam 1-205 (293) Show / Hide 
Range on Protein: 646-838
Range on HMM: 1-205/293
Sequence Identity: 22% (47 aa)

TLTKEELGRGSYAVVTVGNFRGLR--VAVKSLHNMIISDYNLGIFTR--EMTIASQVRHPNLVQFIGATK-VGHPLILTELMST-----SLNHELR---K
  ... .|.||...|  .  .| .  |||| .    ...  . . .|  |  |   ..||| |.....    .|. . .|..       .| . ..   .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

NRL--TNQQILSIAQDVALGLNYLHLFKPQPIIHRDISSPNVLLK-PCTGPAGYEAKVADYGTAKVVQAESTGTVMPGN---PAYAAPEAPI-PDRHSPA
...  . ... ...  .. ||.|.|      |||||. . |.|..  .. .|    |..| | ||... .  .. | .    | |.|||       ..|.
GCFYFSEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDA--CVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPK

MDVYSYSVLLMEL
 |..|. ..| |.
VDMWSCGCILYEM
Kinase AqueK612.AA MLK 862-888 33 7.1e-08 23.53 In-house 265-291 (291) Show / Hide 
Range on Protein: 862-888
Range on HMM: 265-291/291
Sequence Identity: 33% (9 aa)

HMKSLIQRGLNTDPADRPTMAEVIRSL
|.|.|...  |.||..||......  |
HWKKLMKQCWNQDPHKRPSFRQIVQHL
Kinase AqueK612.AA Dicty4 864-890 37 8e-06 15.6 In-house 249-277 (277) Show / Hide 
Range on Protein: 864-890
Range on HMM: 249-277/277
Sequence Identity: 37% (11 aa)

KSLIQRGLNTDPADRPTMAEVIRS--LKK
|.|||. ...||  ||...|.|    |  
KHLIQWCWDHDPQHRPSFEEIIQRRILEH
Kinase AqueK612.AA DRK 866-890 36 4.6e-05 13.12 In-house 234-258 (258) Show / Hide 
Range on Protein: 866-890
Range on HMM: 234-258/258
Sequence Identity: 36% (9 aa)

LIQRGLNTDPADRPTMAEVIRSLKK
|... .|.||  ||.| |..  |  
LMNDCWNEDPQHRPSMQECLERLEA
Kinase AqueK612.AA TKL-Unique 866-888 43 5.6e-05 13.69 In-house 268-290 (290) Show / Hide 
Range on Protein: 866-888
Range on HMM: 268-290/290
Sequence Identity: 43% (10 aa)

LIQRGLNTDPADRPTMAEVIRSL
|||.. . || .||.  |.| .|
LIQQCWHHDPSQRPSFDEIIHRL
Kinase AqueK612.AA Dicty4-Unclassified 863-888 42 0.000201 11.02 In-house 238-263 (263) Show / Hide 
Range on Protein: 863-888
Range on HMM: 238-263/263
Sequence Identity: 42% (11 aa)

MKSLIQRGLNTDPADRPTMAEVIRSL
.|.||   .  ||  |||| ..|  |
WKKLIKWCWHNDPNKRPTMNQIIQYL
Kinase AqueK612.AA LRRK 857-890 26 0.000588 9.87 In-house 318-351 (351) Show / Hide 
Range on Protein: 857-890
Range on HMM: 318-351/351
Sequence Identity: 26% (9 aa)

RVSWSHMKSLIQRGLNTDPADRPTMAEVIRSLKK
.. |  ...|||   ..|| .||.. ...  |. 
CQPWHMYQDLIQHCWQHDPKKRPHFSQIVKRLSQ
Kinase AqueK612.AA Pkinase_Tyr 872-888 47 0.012075 9.58 Pfam 254-270 (270) Show / Hide 
Range on Protein: 872-888
Range on HMM: 254-270/270
Sequence Identity: 47% (8 aa)

NTDPADRPTMAEVIRSL
. ||.||||..|... |
HYDPEDRPTFSEIHEQL
Kinase AqueK612.AA Pkinase 863-888 28 0.139038 6.68 Pfam 266-293 (293) Show / Hide 
Range on Protein: 863-888
Range on HMM: 266-293/293
Sequence Identity: 28% (8 aa)

MKSLIQRGLNTDPADRPTMAEVIRS--L
.|..| . |. ||..||| ...  .  .
CKDFIKWCLCKDPKKRPTAEQILQHPWF