Gene AqueK618 (A.queenslandica)

AqueK618

Species: A.queenslandica
Alias: AqueK618
External Links:
Annotation:

Classification

Group: TKL
Family: MLK
Subfamily: HH-C

Sequence

Name Sequence Type Origin Length Description Download
AqueK618.AA Protein None 786 None Fasta, JSON
AqueK618.kin_dom Protein Kinase Domain None 243 None Fasta, JSON

Protein domain

Protein domains of AqueK618.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kelch_1 AqueK618.AA Kelch_1 26-75 16 18.953511 1.79 Pfam 1-38 (45) Show / Hide 
Range on Protein: 26-75
Range on HMM: 1-38/45
Sequence Identity: 16% (8 aa)

ERGSHRTVSVGDSLYAWAGKQDGLPDVHDSEEKRRITSNIQHFIPSTGQW
 | .|  ..... .|.  |  .            ......  . |.|.||
PRCGHGVCVHNGKIYVIGGCDG------------QYLNSVECYDPETNQW
Kelch_1 AqueK618.AA Kelch_1 87-134 22 0.001792 16.22 Pfam 1-45 (45) Show / Hide 
Range on Protein: 87-134
Range on HMM: 1-45/45
Sequence Identity: 22% (11 aa)

GVRGYCCTAIKDQLYYFGGWCGHDDCDHNSITQLDTVQFQWRELEPTD
  .|..........| .||..|      ||.  .|..  ||... |  
PRCGHGVCVHNGKIYVIGGCDG---QYLNSVECYDPETNQWTRCPPMP
Kelch_1 AqueK618.AA Kelch_1 292-325 17 0.540543 7.33 Pfam 14-45 (45) Show / Hide 
Range on Protein: 292-325
Range on HMM: 14-45/45
Sequence Identity: 17% (6 aa)

LVISGGRDNNNDTLDDCWIFNVTQYSWTKLDIPH
. . ||.|.    |.........  .||..  . 
IYVIGGCDG--QYLNSVECYDPETNQWTRCPPMP
Kinase AqueK618.AA TKL 544-780 20 8.1e-49 168.5 In-house 1-364 (364) Show / Hide 
Range on Protein: 544-780
Range on HMM: 1-364/364
Sequence Identity: 20% (75 aa)

LGIGSYAVVTVGIFRG----------LRVAVKSLHTLVISNYNR-------------------------GLFCREMSMASQIRHPNLVQFIGATKVGT--
.| |....|  |..||            |||| ...   .. ..                           . .|. | |..||||.|||.|. . ..  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------PLILTELM-STNLYKKLQEIELTNQQIFSIAQEVALGLNYLHLFQP-----QPIIHRDVSSPNILLKPCTGP---------AGYEAKV
            . | .|..   .|.  |.      .|....|...|.|.||||  .|      ||||||  |.|||..    .         | . .|.
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-----WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKI

ADYGTAK-LQQSAS-------------------TGTVMPGNPSYAAPEAPIPD----------------QHSPAMDVYSYSVLLIEMNLRRPPEMTTAER
.|.|... ..|| .                   |     |.| . |||.   .                . |...||||. ..| |.  |..|.    ..
CDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPYM

RRQ---------AGNV-----------------------SWLDMKSLIQRGLHANPRGRPTMAQVLKTL
 ..         ....                        . .||.|.|.  ...|. ||.. ..||.|
PMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase AqueK618.AA TKL-Unique 540-730 28 5.6e-30 102.97 In-house 1-221 (290) Show / Hide 
Range on Protein: 540-730
Range on HMM: 1-221/290
Sequence Identity: 28% (63 aa)

TKEELGIGSYAVVTVGIFRGLRVAVKSLHT-LVISNYNRGLFCREMSMASQIR-HPNLVQFIGATK---VGTP--LILTELMSTN-LYKKLQ--------
  . .| |.|..|  |..||  ||.|..|    .||  .  | .| .  . .. |||.|...|...   |  |   | .| .. . ||. |.        
FWNKIGEGGYGQVYKGKWRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNN

---EIELTNQQIFSIAQEVALGLNYLHLFQPQPIIHRDVSSPNILLKPCTGPAGYEAKVADYGTAKLQQSASTGTVM----------PGNPSYAAPEAPI
   ...|..||. ..|. .|.|..|||  .|  |||||  |.|.|.      | . .|..| |..|.. . ...|.            |.. ..|||   
NNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLR

P--DQHSPAMDVYSYSVLLIEM
   .| |   ||||... |.|.
MNFCQYSEKSDVYSFGIVLWEI
Kinase AqueK618.AA MLK 538-730 25 6.6e-28 93.96 In-house 1-229 (291) Show / Hide 
Range on Protein: 538-730
Range on HMM: 1-229/291
Sequence Identity: 25% (59 aa)

TLTKEELGIGSYAVVTVGIFRGLR-----VAVKSLH----TLVISNYNRGLFCREMSMASQIRHPN----LVQFIGA-TKVGT-PLILTELMST-NLYKK
 ...| .| ||. .|  | .|. .     ||||  .      ...   .  | .|   .. ..|||     .|| |. .. .   .|..| ..   ||  
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNV

LQEIE---------------LTNQQIFSIAQEVALGLNYLHLFQPQPIIHRDVSSPNILLKP-CTGPAGYEAKVADYGTAK-LQQSASTGTVMPGNPSYA
| ...                . ......|  .| |..|||  .|.||||||  |.|||.   |   ..  .|..| ||.. ..|. .. . ..|.. . 
LHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMMSNAGTYAWM

APEAP---IPDQHSPAMDVYSYSVLLIEM
|||.      .. | . ||.|. |.| ||
APEVIQQFRCEKYSEKCDVWSWGVVLWEM
Kinase AqueK618.AA S_TKc 538-778 20 2.1e-24 88.35 SMART 1-220 (231) Show / Hide 
Range on Protein: 538-778
Range on HMM: 1-220/231
Sequence Identity: 20% (52 aa)

TLTKEELGIGSYAVVTVGIFRG--LRVAVKSLHTLVISNYNRGLFCREMSMASQIRHPNLVQFIGATKVGTPLILTELMST---NLYKKLQEIE------
    ...| |....|  .. ..   .||.| ..           ..||... .. .|||.|.....   .   . .|....   .|.. ...        
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-LTNQQIFSIAQEVALGLNYLHLFQPQPIIHRDVSSPNILLKPCTGPAGYEAKVADYGTAKLQQSASTGTVMPGNPSYAAPEAPIPDQHSP-AMDVYSYS
 ..  .. .........|.|.|    . |||||.   ||||         . |..| | |..       | . | | | |||     .... . |..|  
PFPE-HARFYMYQICCALEYCHS---HGIIHRDLKPENILLDE-------HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCG

VLLIEMNLRRPPEMTTAERRRQAGNVSWLDMKSLIQRGLHANPRGRPTMAQVLK
..|.||  ..||   . ..  .       ..|..|.. |. .|. |||  ..|.
CILYEMLCGYPPFP-QMQMMFKKIG--SPEAKDFIRKCLQKDPEKRPTA-EALQ
Kinase AqueK618.AA TK 538-780 14 1.7e-23 74.93 In-house 1-486 (486) Show / Hide 
Range on Protein: 538-780
Range on HMM: 1-486/486
Sequence Identity: 14% (69 aa)

TLTKEELGIGSYA---VVTVGIFRGL---------------------------RVAVKSLHTLVISNYNRGL------------FCREMSMASQIR----
    ..|| | .    .|  |. ||.                           .|||| |.    .. .. .            |..|...... .    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HPNLVQFIG-ATKVGT------------PLILTELMS-TN----LYKKLQEIE----------------------------------------------
 |||.|...|  |....            ..|..|.|.  .    | . |..                                                
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------LTNQQIFSIAQEVALGLNYLHLFQP---QPIIHRDVSSPNILLKPCTG------PAGYEAKVADYG---
                               || .|   ... .| |. |||  .    | ..|||.   |.|.             |. .|.||.|   
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----TAKLQQSASTGTVMPGNPS---------------------------YAAPEAPI---------PDQHSPAMDVYSYSVLLIEMNL--RRPPE--M
      |.  .| .  ... .                              . |||.              .... ||.|. ||. |.    . |.   |
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

TT------------------------------AERRRQA--GNVS-W------------LDMKSLIQRGLHANPRGRPTMAQVLKTL
.                                .| |..   . . |             ..  |.|.  |..|. |||..|... |
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase AqueK618.AA STE 539-736 17 2.1e-21 72.4 In-house 1-267 (359) Show / Hide 
Range on Protein: 539-736
Range on HMM: 1-267/359
Sequence Identity: 17% (49 aa)

LTK-EELGIGSYAVVTVGIFR-----------------GLRVAVKSLH---------------TLVISNYNRGLFCREMSMASQIR--HPNLVQFIGATK
... |..| |.. .|  .. .                 | ..|.| ..               .  . . ..  . .|... .. .  ||| |...|.  
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

VG--------TPLILTELMS-TNLYKKLQ---EIELT------------NQQIFSIAQEVALG-LNYLHLFQPQPIIHRDVSSPNILLKPCTGPAGYEAK
..        .  |  |.|.   | . ..   ..  .             .||  |....  | |.|||  .   |||||. . ||||          .|
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH---IIHRDIKPANILL----------VK

VADYGTAKLQQS-----------------ASTGTVMPGNPSYAAPEAPIP------DQHSPAMDVYSYSVLLIEMNLRRPP
 .| |...  ..                 ..  . . | | . |||   .      ....   |..|   ..|||   .||
LCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPP
Kinase AqueK618.AA Dicty4 540-730 30 1.5e-19 62.04 In-house 3-210 (277) Show / Hide 
Range on Protein: 540-730
Range on HMM: 3-210/277
Sequence Identity: 30% (66 aa)

TKEELGIGSYAVVTVGIFRGLRVAVKSL--HTLVISNYNRGLFCREMSMASQIRHPNLVQFIGA-T----KVGTPLILTELM-STNLYKKLQE-------
. ...| ||.. |  |. ||  |||| |  |  . . .    | .| .  ..|||||...| || |    . |...| ||.| ..|||. |         
IEQRIGKGSFGEVYKGTWRGKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSEQQQ

-IELTNQQIFS---IAQEVALGLNYLHLFQPQPIIHRDVSSPNILLKPCTGPAGYEAKVADYGTAK-----LQQSA-STGTVMPGNPSYAAPEAPIPDQH
 |.|    | .   .|  .|.|.|.||   |  |||||  | |.|       . . .||.| | ..      ....  ....  | | . |||    .  
SIKLDWPLIKRAMRMAFDAARGMNWLHCCNPV-IIHRDLKSHNLLVD-----KNWRVKVCDFGLSQYMKKHEDHKDNQMTAC--GTPCWMAPEVMMHQPY

SPAMDVYSYSVLLIEM
  . ||||.. .| |.
NEKADVYSFGIVLWEI
Kinase AqueK618.AA Pkinase 538-780 20 6.8e-19 67.89 Pfam 1-293 (293) Show / Hide 
Range on Protein: 538-780
Range on HMM: 1-293/293
Sequence Identity: 20% (62 aa)

TLTKEELGIGSYAVVTVGIFRGLR--VAVKSLHTLVISNYNRGLFCR--EMSMASQIRHPNLVQFIGATK-VGTPLILTELMST-----NLYKKLQ---E
  ... .| ||...|  .. .| .  |||| .    ..   .    |  | ..   ..||| |.....    . . . .|..        |.  ..   .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

IEL--TNQQIFSIAQEVALGLNYLHLFQPQPIIHRDVSSPNILLK-PCTGPAGYEAKVADYGTAKL--QQSASTGTVMPGNPSYAAPEAPI-PDQHSPAM
  .  . ... ... ... ||.|.|      |||||. . |||..  .. .|    |..| | ||.    . |  |.  | | |.|||       ..|. 
GCFYFSEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDA--CVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKV

DVYSYSVLLIEMNLRRPPEMTT------AERRRQAGNVS---------W---------------------LDMKSLIQRGLHANPRGRPTMAQVLKT--L
|..|. ..|.|| ..|||           .. . . . .         |                      ..|..| . |. .|  ||| .|.|.   .
DMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase AqueK618.AA CZAK 634-730 31 1.4e-16 56.84 In-house 109-215 (279) Show / Hide 
Range on Protein: 634-730
Range on HMM: 109-215/279
Sequence Identity: 31% (34 aa)

SIAQEVALGLNYLHL-FQPQPIIHRDVSSPNILLKPCTG--------PAGYEAKVADYGTA---KLQQSASTGTVMPGNPSYAAPEAPIPDQHSPAMDVY
..|  .| | ||||  . | ||.||| || ||||                  .|..|.|     . | .  | |.  |   . |||  . .  ..  |||
NMAIDIARGMNYLHDNWKPNPILHRDLSSRNILLDHSYTPKNPVVSSRQDIICKINDFGLSREMMEQPFEMTQTM--GCLCWMAPECFKGENYTEKVDVY

SYSVLLIEM
|.  .| ..
SFGMILWCI
Kinase AqueK618.AA LRRK 538-707 22 2.1e-16 54.51 In-house 1-249 (351) Show / Hide 
Range on Protein: 538-707
Range on HMM: 1-249/351
Sequence Identity: 22% (57 aa)

TLTKEELGIGSYA-VVTVGIFRG----------------------------LRVAVKSLHTL----------------------------------VISN
    |..| |... .|  ...||                              ||.|....                                    . .
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

YNRGLFCREMSMASQIRHPNLVQFIGATKVGTPLIL-TELMST-NLYKKLQ---E-------IELTNQQIFSIAQEVALGLNYLHLFQPQPIIHRDVSSP
..  .| .|... |  .|||.|. .| .    ||.. .|...  .||. |.   .       .... . .  || ..| |..||| . | ||||||  ||
FR--EFRHEVWIMSHLNHPNIVSLKGFCI--HPLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNP-PIIHRDLKSP

NILLKPCTGP-------AGYEAKVADYGTAK-LQQSASTG--TVMPGNPSYAAPE
||||.  . .       | . ||.||.|.     |.  .|    . ||| . |||
NILLWSSPQNHSPNYPNAHVCAKIADFGISRMF-QCFHMGVAKGCVGNPGWMAPE
Kinase AqueK618.AA Dicty4-Unclassified 541-730 27 5.8e-16 51.13 In-house 4-201 (263) Show / Hide 
Range on Protein: 541-730
Range on HMM: 4-201/263
Sequence Identity: 27% (57 aa)

KEELGIGSYAVVTVGIFRGLRVAVKSLHTLVISNYNRGL--FCREMSMASQIRHPNLVQFIGATKVG-----TPLILTELM-STNLY---K-----KLQE
  ..| |  . |  |. .|  |||| .     .     .  | .|  .   | |||||.  |.         |  | .|.| . ||          . | 
DQFIGKGHFSKVHKGNWKGKDVAVKKFNENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYCINPRSHKSTMCIVMEFMHKGNLFEVIHSKPSEQQQP

IELTNQQIFSIAQEVALGLNYLHLFQPQPIIHRDVSSPNILLKPCTGPAGYEAKVADYGTAKLQQSASTGTVMPGNPSYAAPEAPIPDQHSPAMDVYSYS
| |    |  .| ..| |. .||      .||||. | |||.        . .|.|| | .       . |   | |   .||         . ||||| 
IKLDDTLIIKYAFDIAQGMQHLHTRN---FIHRDIKSSNILMD-----KHFNIKIADFGISRVIDFNFNMTTIAGTPKWESPECLMHESYNQKSDVYSYA

VLLIEM
..| |.
MMLYEL
Kinase AqueK618.AA TyrKc 538-780 19 2.2e-14 9.87 SMART 1-280 (280) Show / Hide 
Range on Protein: 538-780
Range on HMM: 1-280/280
Sequence Identity: 19% (58 aa)

TLTKEELGIGSYAVVTVGIFRGLRVAVKSLHTLVISNYNRGLFCREMSMASQI--RHPNLVQFIGATKV--------GTPLILTELMST-NLYKKLQEIE
   ...|| | . .|  |. . . ||||.|.        |  |.||... ...  .|||.|...|.           . ..|..|.|.  .| . |.. .
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR

--LTNQQIFSIAQEVALGLNYLHLFQPQPIIHRDVSSPNILLKPCTGPAGYEAKVADYGTAKLQQSA-----STGTVMP----GNPS-----YAAPEAPI
  |....  |..  .| | .|||     ..||||    |.|..         .|..| | ..   .      |. . ..    |  .       |||.  
PKLCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENH-----TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECIN

PDQHSPAMDVYSYSVLL-----------IE-----MNLRRPPEMTTAERRRQAGNV--------SWLDMKSLIQRGLHANPRGRPTMAQVLKTL
    ... ||.|. |..            .     |. ..  |   . .|.                .| .....  |..|  |||.... . .
YGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Pkinase_Tyr AqueK618.AA Pkinase_Tyr 537-683 26 7.2e-14 47.6 Pfam 1-156 (270) Show / Hide 
Range on Protein: 537-683
Range on HMM: 1-156/270
Sequence Identity: 26% (44 aa)

VTLTKEELGIGSYAVVTVGIFR------GLRVAVKSL-HTLVIS-NYNRGLFCREMSMASQI-RHPNLVQFIGATK-VGTP---LILTELMST-NLYKKL
.|.  ..|| |.. .|  |. .      .. ||||.| ..   . |  |  | ||... .|. .|||.|...|.    | |   .| .|.|   .|.. |
ITFG-KKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQN-CREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

QE-----IELTNQQIFSIAQEVALGLNYLHLFQPQPIIHRDVSSPNILLKPCTGPAGYEAKVADYG
..       || ... ......| |..||.  .   .||||.   |.|..      .  .|..| |
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKN---CIHRDLAARNCLVTE-----NNVVKICDFG
Kinase AqueK618.AA HH498 630-730 36 3.2e-13 37.85 In-house 121-219 (284) Show / Hide 
Range on Protein: 630-730
Range on HMM: 121-219/284
Sequence Identity: 36% (38 aa)

QQIFSIAQEVALGLNYLHLFQPQPIIHRDVSSPNILLKPCTGPAGYEAKVADYGTAKLQQSAS--TGTVMPGNPSYAAPEAPI-PDQHSPAMDVYSYSVL
| .  |. .|| | ||||   ..||||||  | |||.      .   |.|||.|     ..    . |  |||. . |||      . |   ||.||   
QSKMTISVDVAHGMNYLHNSLKHPIIHRDLNSHNILIH-----EDGHAVVADFGESRFVCDMHDDNMTKQPGNLRWMAPEVFSQCQKYSIKVDVFSYAMC

LIEM
. ||
IWEM
Kinase AqueK618.AA Dicty4 756-782 27 2e-07 21.04 In-house 249-277 (277) Show / Hide 
Range on Protein: 756-782
Range on HMM: 249-277/277
Sequence Identity: 27% (8 aa)

KSLIQRGLHANPRGRPTMAQVLKT--LNE
|.|||. .. .|  ||.......   |..
KHLIQWCWDHDPQHRPSFEEIIQRRILEH
Kinase AqueK618.AA MLK 755-780 26 3.1e-07 21.28 In-house 266-291 (291) Show / Hide 
Range on Protein: 755-780
Range on HMM: 266-291/291
Sequence Identity: 26% (7 aa)

MKSLIQRGLHANPRGRPTMAQVLKTL
.|.|...  ...|. ||...|... |
WKKLMKQCWNQDPHKRPSFRQIVQHL
Kinase AqueK618.AA HH498 540-602 31 4.5e-07 18.05 In-house 3-71 (284) Show / Hide 
Range on Protein: 540-602
Range on HMM: 3-71/284
Sequence Identity: 31% (22 aa)

TKEELGIGSYAVVTVGIFRGLRVAVKSLHTLVISNYNR------GLFCREMSMASQIRHPNLVQFIGAT
..|  | ||.  |  | .|.  ||||      ..            |||| |. ..  ||. |||..|.
FHEKIGSGSFGKVYKGEWRNKIVAVKRYRAMAFCCKSDSYQWIVDMFCREVSIMCRLNHPCVVQFVYAC
Kinase AqueK618.AA HH498 757-780 37 2e-06 16.28 In-house 261-284 (284) Show / Hide 
Range on Protein: 757-780
Range on HMM: 261-284/284
Sequence Identity: 37% (9 aa)

SLIQRGLHANPRGRPTMAQVLKTL
.|||.. |..| .||. .|..  |
NLIQMCWHPCPENRPDFDQIVTIL
Kinase AqueK618.AA LRRK 752-782 32 1.3e-05 15.8 In-house 321-351 (351) Show / Hide 
Range on Protein: 752-782
Range on HMM: 321-351/351
Sequence Identity: 32% (10 aa)

WLDMKSLIQRGLHANPRGRPTMAQVLKTLNE
| ....|||   ...|. ||.. |..|.| .
WHMYQDLIQHCWQHDPKKRPHFSQIVKRLSQ
Kinase AqueK618.AA CZAK 558-601 39 4.4e-05 14.57 In-house 21-68 (279) Show / Hide 
Range on Protein: 558-601
Range on HMM: 21-68/279
Sequence Identity: 39% (19 aa)

RGLRVAVKSLHTLVISNYNR----GLFCREMSMASQIRHPNLVQFIGA
||  ||.| .|     |         | .| |  |  .||| |||.||
RGKDVAIKIIHRNQFRNKDENKEENMFQKEVSIMSKLCHPNCVQFLGA
Kinase AqueK618.AA Dicty4-Unclassified 755-780 42 0.000177 11.21 In-house 238-263 (263) Show / Hide 
Range on Protein: 755-780
Range on HMM: 238-263/263
Sequence Identity: 42% (11 aa)

MKSLIQRGLHANPRGRPTMAQVLKTL
.|.||   .|  |. |||| |. . |
WKKLIKWCWHNDPNKRPTMNQIIQYL
Kinase AqueK618.AA TKL-Unique 758-780 34 0.000683 9.82 In-house 268-290 (290) Show / Hide 
Range on Protein: 758-780
Range on HMM: 268-290/290
Sequence Identity: 34% (8 aa)

LIQRGLHANPRGRPTMAQVLKTL
|||.. | .|  ||.  .... |
LIQQCWHHDPSQRPSFDEIIHRL
Kinase AqueK618.AA Pkinase_Tyr 764-780 35 0.428587 4.33 Pfam 254-270 (270) Show / Hide 
Range on Protein: 764-780
Range on HMM: 254-270/270
Sequence Identity: 35% (6 aa)

HANPRGRPTMAQVLKTL
|..|  |||.....  |
HYDPEDRPTFSEIHEQL