Gene AqueK619 (A.queenslandica)

AqueK619

Species: A.queenslandica
Alias: AqueK619
External Links:
Annotation:

Classification

Group: TKL
Family: MLK
Subfamily: HH-C

Sequence

Name Sequence Type Origin Length Description Download
AqueK619.AA Protein None 754 None Fasta, JSON
AqueK619.kin_dom Protein Kinase Domain None 244 None Fasta, JSON

Protein domain

Protein domains of AqueK619.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kelch_1 AqueK619.AA Kelch_1 9-65 17 0.005305 14.53 Pfam 1-45 (45) Show / Hide 
Range on Protein: 9-65
Range on HMM: 1-45/45
Sequence Identity: 17% (10 aa)

GRAHHQTVSVGNSLYVWAGYQDGLPGAHDSIEKRRFTSSIQQITPSTGQWVTRSTTG
 |..|  ..... .||  |. .            ....|.    |.|.||   .. .
PRCGHGVCVHNGKIYVIGGCDG------------QYLNSVECYDPETNQWTRCPPMP
Kelch_1 AqueK619.AA Kelch_1 70-117 22 1.500685 5.74 Pfam 1-45 (45) Show / Hide 
Range on Protein: 70-117
Range on HMM: 1-45/45
Sequence Identity: 22% (11 aa)

GVLGYCCVAVNELLYYFLGYCGHGDCFYNSITQLDTVSLQWRELEPTD
   |......| ..| . |..|    . ||.  .|... ||... |  
PRCGHGVCVHNGKIYVIGGCDG---QYLNSVECYDPETNQWTRCPPMP
Kelch_1 AqueK619.AA Kelch_1 257-307 15 0.062471 10.69 Pfam 1-45 (45) Show / Hide 
Range on Protein: 257-307
Range on HMM: 1-45/45
Sequence Identity: 15% (8 aa)

RYRHAGAVVITGPDSPMLVIAGGRDMNNDTLDDCWIFNITQSLWIKLDAPQ
. ...|..|. |     . ..||.|     |....... .   | ..  ..
PRCGHGVCVHNG----KIYVIGGCDG--QYLNSVECYDPETNQWTRCPPMP
Kinase AqueK619.AA TKL 512-749 20 1.5e-52 180.88 In-house 1-364 (364) Show / Hide 
Range on Protein: 512-749
Range on HMM: 1-364/364
Sequence Identity: 20% (77 aa)

LGRGSYAVVTVGIFRG----------LRVAVKSLHTIIISDYNQ-------------------------GLFSREMSIASRVRHPNLVQFIGATK-----
.|.|....|  |..||            |||| ...   .  .                            . .|. . || ||||.|||.|. .     
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

---------VGNPLILTELM-STSLNHVLQKNRLTNQQILSIAQDVALGLNYLHLLKP-----QPIIHRDVSSPNVLLKPRTGP---------AGYEAKV
          |.. | .|..   || |.|.      .|....|.|.|.|.||||  .|      ||||||  |.|.|..    .         | . .|.
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-----WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKI

ADYGTAKLQQQGTS-------------------TGTVMPGNPAYAAPEARDPD----------------QHSPAMDVYSYSVLLMEVNLCCPPEM-----
.|.|...  .| ..                   |     |.|.. |||. . .                . |...||||. ..| |.  .|.|.      
CDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPYM

------------TAVERARQSGTV---------------SWSDMKSLIQRGLKADPIDRPTMTQVIESL
              |   ..  ..                . .||.|.|.  ..|| .||....... |
PMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase AqueK619.AA MLK 506-696 26 1e-37 128.44 In-house 1-226 (291) Show / Hide 
Range on Protein: 506-696
Range on HMM: 1-226/291
Sequence Identity: 26% (60 aa)

TLTKEELGRGSYAVVTVGIFRGLR-----VAVKSLHTIIISDYNQ-----GLFSREMSIASRVRHPN----LVQFIGA-TKVGN-PLILTELMST-SLNH
 ...| .| ||. .|  | .|. .     ||||  .. |. |  .       | .|  ......|||     .|| |. .. ..  .|..| ..  ||..
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYN

VLQKNR---------------LTNQQILSIAQDVALGLNYLHLLKPQPIIHRDVSSPNVLLKP--RTGPAGYEAKVADYGTAK-LQQQGTSTGTVMPGNP
||  .|                . ......| ..| |..||| ..|.||||||  |.|.|.        ..  .|..| ||.. ..| . .. . ..|..
VLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICH-DMHHGTLKICDFGTSRDWHQMC-TNMMSNAGTY

AYAAPEAR---DPDQHSPAMDVYSYSVLL
|. |||..     .. | . ||.|. |.|
AWMAPEVIQQFRCEKYSEKCDVWSWGVVL
Kinase AqueK619.AA TKL-Unique 508-698 28 2e-33 115.28 In-house 1-220 (290) Show / Hide 
Range on Protein: 508-698
Range on HMM: 1-220/290
Sequence Identity: 28% (63 aa)

TKEELGRGSYAVVTVGIFRGLRVAVKSLHT--IIISDYNQGLFSREMSIASRVR-HPNLVQFIGATK---VGNP--LILTELMST-SLNHVLQ-------
  . .|.|.|..|  |..||  ||.|..|    . ..  |  |..| .. .. . |||.|...|...   | .|   | .| ..  ||. ||.       
FWNKIGEGGYGQVYKGKWRGYPVAIKQFHPNEDSSNEMMQE-FENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNN

----KNRLTNQQILSIAQDVALGLNYLHLLKPQPIIHRDVSSPNVLLKPRTGPAGYEAKVADYGTAKLQQQGTSTGTVMP---------GNPAYAAPEAR
    .. |..||....|.|.|.|..||| ..|  |||||  |.|.|.  .   | . .|..| |..|.. . . . . ..         |.. ..|||  
NNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVL

DP--DQHSPAMDVYSYSVLLME
    .| |   ||||... | |
RMNFCQYSEKSDVYSFGIVLWE
Kinase AqueK619.AA TK 506-749 14 5.9e-32 103.83 In-house 1-486 (486) Show / Hide 
Range on Protein: 506-749
Range on HMM: 1-486/486
Sequence Identity: 14% (72 aa)

TLTKEELGRGSYA---VVTVGIFRGL---------------------------RVAVKSLHTIIISDYNQGL---------------FSREMSIAS--RV
    ..||.| .    .|  |. ||.                           .|||| |.    .. .. .               . .||.. .    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

RHPNLVQFIG-ATKVGN------------PLILTELMS-TS----LNHVLQKNR----------------------------------------------
.|||.|...|  |....            ..|..|.|.  .    | . |.|.|                                              
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------LTNQQILSIAQDVALGLNYLHLLKP---QPIIHRDVSSPNVLLKPRTG------PAGYEAKVADYGTAK
                               || .| | .....| |. ||| ..    | ..|||.   |.|.  .          |. .|.||.| ..
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----LQQQGTS--TGTVMPGNPA---------------------------YAAPEARD---------PDQHSPAMDVYSYSVLLMEVN-LC-CPPE--M
     |     |    ... .  .                           . |||. .            .... ||.|. ||. |.  ..  |.   |
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

TA---------------------------------VERARQSGTVSW------------SDMKSLIQRGLKADPIDRPTMTQVIESL
.                                   ....  .  .|             ..  |.|.  ..|| ||||..|. | |
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase AqueK619.AA S_TKc 506-752 19 3.5e-30 107.53 SMART 1-231 (231) Show / Hide 
Range on Protein: 506-752
Range on HMM: 1-231/231
Sequence Identity: 19% (52 aa)

TLTKEELGRGSYAVVTVGIFRG--LRVAVKSLHTIIISDYNQGLFSREMSIASRVRHPNLVQFIGATKVGNPLILTELMST---SLNHVLQKNR------
    ...|.|....|  .. ..   .||.| ..           . ||..| .. .|||.|.....   ..  . .|....   .| ....|..      
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-LTNQQILSIAQDVALGLNYLHLLKPQPIIHRDVSSPNVLLKPRTGPAGYEAKVADYGTAKLQQQGTSTGTVMPGNPAYAAPEARDPDQHSP-AMDVYSY
 ..  .. .... ....|.|.| ..   |||||.   |.||         . |..| | |..        | . | | | |||     .... . |..| 
PFPE-HARFYMYQICCALEYCHSHG---IIHRDLKPENILLDE-------HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSC

SVLLMEVNLCCPPEMTAVERARQSGTVSWSDMKSLIQRGLKADPIDRPTMTQVIE------SLKRI
 ..| |    .||    ...  .      ...|..|.. |. || .|||  .. .      .   .
GCILYEMLCGYPPFP-QMQMMFKKIG--SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK619.AA CZAK 507-699 29 1.6e-26 93.42 In-house 1-215 (279) Show / Hide 
Range on Protein: 507-699
Range on HMM: 1-215/279
Sequence Identity: 29% (63 aa)

LTKE-ELGRGSYAVVTVGIFRGLRVAVKSLHTIIISDYNQ----GLFSREMSIASRVRHPNLVQFIGATKVGN---PLILTELMS-TSLNHVL-QKNRLT
|. . . |.| .  |  .  ||  ||.| .| .   .         | .| || |  .||| |||.||   ..     | .| |   ||   |  .  . 
LKFGQTIGQGFFGEVYKAYWRGKDVAIKIIHRNQFRNKDENKEENMFQKEVSIMSKLCHPNCVQFLGACSEDGPNHHCIVMEWMGGGSLRRLLTDHYFYH

NQ---QILSIAQDVALGLNYLHL-LKPQPIIHRDVSSPNVLLKPRTG--------PAGYEAKVADYGTAKLQQQGTSTGTVMPGNPAYAAPEARDPDQHS
 |     ...| |.| | ||||   || ||.||| || |.||                  .|..|.|  ..   . .  |   |  .. |||    .  .
KQNPHLQWNMAIDIARGMNYLHDNWKPNPILHRDLSSRNILLDHSYTPKNPVVSSRQDIICKINDFGLSREMMEQPFEMTQTMGCLCWMAPECFKGENYT

PAMDVYSYSVLLMEV
.  ||||.  .| ..
EKVDVYSFGMILWCI
Kinase AqueK619.AA Dicty4 508-676 29 2.3e-24 78.3 In-house 3-187 (277) Show / Hide 
Range on Protein: 508-676
Range on HMM: 3-187/277
Sequence Identity: 29% (57 aa)

TKEELGRGSYAVVTVGIFRGLRVAVKSL--HTIIISDYNQGLFSREMSIASRVRHPNLVQFIGA-T----KVGNPLILTELM-STSLNHVLQK------N
. ...|.||.. |  |. ||  |||| |  | .  . .    | .| .| .  ||||...| || |    . | ..| ||.| ...|  .| .       
IEQRIGKGSFGEVYKGTWRGKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSEQQQ

RLTNQ--QILS---IAQDVALGLNYLHLLKPQPIIHRDVSSPNVLLKPRTGPAGYEAKVADYGTAKLQQQGTSTGT---VMPGNPAYAAPE
. . .   |..   .| |.|.|.|.||   |  |||||  | | |       . . .||.| | ... . ... ..    . | |.. |||
SIKLDWPLIKRAMRMAFDAARGMNWLHCCNPV-IIHRDLKSHNLLVD-----KNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPE
Kinase AqueK619.AA STE 507-676 18 5.4e-23 78.1 In-house 1-232 (359) Show / Hide 
Range on Protein: 507-676
Range on HMM: 1-232/359
Sequence Identity: 18% (45 aa)

LTK-EELGRGSYAVVTVGIFR-----------------GLRVAVKSLH---------------TIIISDYNQGLFSREMSIASRVR--HPNLVQFIGATK
... |..|.|.. .|  .. .                 | ..|.| ..               . .. . ..  . .|..| .. .  ||| |...|.  
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

VG--------NPLILTELMS-TSLNHVLQKN---------------RLTNQQILSIAQDVALG-LNYLHLLKPQPIIHRDVSSPNVLLKPRTGPAGYEAK
..        .  |  |.|.  ||  .....               |.  .||  |....  | |.||| ..   |||||. . |.||          .|
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH---IIHRDIKPANILL----------VK

VADYGTAKLQQQG--------------TSTGT--VMPGNPAYAAPE
 .| |...  ..               |. .    . | | . |||
LCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPE
Kinase AqueK619.AA LRRK 506-696 21 1e-22 77.17 In-house 1-272 (351) Show / Hide 
Range on Protein: 506-696
Range on HMM: 1-272/351
Sequence Identity: 21% (61 aa)

TLTKEELGRGSYA-VVTVGIFRG----------------------------LRVAVKSLHTI----------------------------------IISD
    |..|||... .|  ...||                              ||.|.....                                   .  
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

YNQGLFSREMSIASRVRHPNLVQFIGATKVGNPLIL-TELMST-SLNHVLQKNR----------LTNQQILSIAQDVALGLNYLHLLKPQPIIHRDVSSP
..  .| .|..| |. .|||.|. .| .   .||.. .|...  .|.|.|....          .. . .| || ..| |..|||  .| ||||||  ||
FR--EFRHEVWIMSHLNHPNIVSLKGFCI--HPLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNP-PIIHRDLKSP

NVLL-KPRTGP------AGYEAKVADYGTAK----LQQQGTSTGTVMPGNPAYAAPEARDPD---QHSPAMDVYSYSVLL
|.|| .  ...      | . ||.||.|.      ..  .... .   ||| . ||| .  .   . .   |.||. ..|
NILLWSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMGVAKGCV---GNPGWMAPEIMRYNGEEEYTEKVDCYSFGMIL
Kinase AqueK619.AA HH498 508-698 30 2.7e-20 60.66 In-house 3-218 (284) Show / Hide 
Range on Protein: 508-698
Range on HMM: 3-218/284
Sequence Identity: 30% (67 aa)

TKEELGRGSYAVVTVGIFRGLRVAVKSLHTIIISDYNQ------GLFSREMSIASRVRHPNLVQFIGATKVGNP---LILTELMST-SLNHVL-------
..|  | ||.  |  | .|.  ||||      ..            | || || .|  ||. |||..|. .  |   .| |.  .  ||  .|       
FHEKIGSGSFGKVYKGEWRNKIVAVKRYRAMAFCCKSDSYQWIVDMFCREVSIMCRLNHPCVVQFVYAC-CDDPSQFAIVTQYCDNGSLFSILNTIPIGG

-------QKNR-----LTNQQILSIAQDVALGLNYLHLLKPQPIIHRDVSSPNVLLKPRTGPAGYEAKVADYGTAK-LQQQGTSTGTVMPGNPAYAAPEA
         ..     .  | .. |. ||| | ||||   ..||||||  | |.|.  . |     |.|||.|    ... .  . |  |||. . ||| 
AGANNNNHNQKNNYRIMDLQSKMTISVDVAHGMNYLHNSLKHPIIHRDLNSHNILIH-EDG----HAVVADFGESRFVCDMHDDNMTKQPGNLRWMAPEV

RD-PDQHSPAMDVYSYSVLLME
     . |   ||.||   . |
FSQCQKYSIKVDVFSYAMCIWE
Pkinase_Tyr AqueK619.AA Pkinase_Tyr 505-651 26 4.1e-20 68.76 Pfam 1-156 (270) Show / Hide 
Range on Protein: 505-651
Range on HMM: 1-156/270
Sequence Identity: 26% (44 aa)

VTLTKEELGRGSYAVVTVGIFR------GLRVAVKSLHTIIISDYN--QGLFSREMSIASRV-RHPNLVQFIGATK-VGNP---LILTELMST-SLNHVL
.|.  ..||.|.. .|  |. .      .. ||||.|     .. .  .  | ||..| .   .|||.|...|.    | |   .| .|.|   .| . |
ITFG-KKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

QKN-----RLTNQQILSIAQDVALGLNYLHLLKPQPIIHRDVSSPNVLLKPRTGPAGYEAKVADYG
.|.     .|| ...|......| |..||.  .   .||||.   |.|..      .  .|..| |
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKN---CIHRDLAARNCLVT-----ENNVVKICDFG
Kinase AqueK619.AA TK-Unique 506-699 20 2e-18 60.26 In-house 1-232 (294) Show / Hide 
Range on Protein: 506-699
Range on HMM: 1-232/294
Sequence Identity: 20% (48 aa)

TLTKEELGRGSYAVVTVGIFRGLR---VAVKSLHTIIISDYNQGL----FSREMSIASRVR-HPNLVQFIGATK-VG-NPLILTELMSTS-LNHVLQKNR
   ....|.|..  |  | ..|.     . |.  .    |.....    | .| .. . .  |||.||..|..   . ...|. | .. . | | |...|
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR

---------------------------LTNQQILSIAQDVALGLNYLHLLKPQPIIHRDVSSPNVLLKPRTGPAGYEAKVADYGTAK----LQQQGTSTG
                           .. .. ...| ..| |..||. . .. |.|||... ||||       ....|..|.| |.     ... ....
PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQ-RKKIVHRDLCARNVLLTE-----DKVCKICDFGMARDVYTNGVYSMMCS

TVMPGNPAYAAPEA-R--DPDQHSPAMDVYSYSVLLMEV
  .  . .. |||. .  .   |..  ||.|. ||. |.
QGRIPI-RWMAPESLKCYHGMYHTTKSDVWSFGVLMWEI
Kinase AqueK619.AA Pkinase 506-699 23 3.5e-17 61.85 Pfam 1-205 (293) Show / Hide 
Range on Protein: 506-699
Range on HMM: 1-205/293
Sequence Identity: 23% (50 aa)

TLTKEELGRGSYAVVTVGIFRGLR--VAVKSLHTIIISD-YNQGLFS-REMSIASRVRHPNLVQFIGATK-VGNPLILTELMST-----SLNHVLQ---K
  ... .|.||...|  .. .| .  |||| .    ...  .| ..  .| .|  |..||| |.....    ... . .|..       .| ....   .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

NRL--TNQQILSIAQDVALGLNYLHLLKPQPIIHRDVSSPNVLLKPRTGPAGYEAKVADYGTAKLQ-QQGTSTGTVMPGNPAYAAPEA-RDPDQHSPAMD
...  . ... ...  .. ||.|.|      |||||. . |.|.. ..|  .   |..| | ||.      |  |.  | | |.|||  |.   ..|. |
GCFYFSEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILID-NNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVD

VYSYSVLLMEV
..|. ..| |.
MWSCGCILYEM
Kinase AqueK619.AA TyrKc 506-749 22 5.4e-17 52.05 SMART 1-280 (280) Show / Hide 
Range on Protein: 506-749
Range on HMM: 1-280/280
Sequence Identity: 22% (65 aa)

TLTKEELGRGSYAVVTVGIFRGLRVAVKSLHTIIISDYNQGLFSREMSIASRV--RHPNLVQFIGATKV--------GNPLILTELMST-SLNHVLQKNR
   ...||.| . .|  |. . . ||||.|.        .  | ||..| ...  .|||.|...|.           . ..|..|.|.  .|.. |.|.|
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR

--LTNQQILSIAQDVALGLNYLHLLKPQPIIHRDVSSPNVLLKPRTGPAGYEAKVADYGTAKLQQQG------TSTGTVM---PGNP----AYAAPEARD
  |.... ||.. ..| | .|||     ..||||    |.|.. .       .|..| | ..    .      ... ...    |.        |||. .
PKLCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENH-----TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECIN

PDQHSPAMDVYSYSVLLMEV-NLCCPPE-------MTAVE---------RARQSGTV-------SWSDMKSLIQRGLKADPIDRPTMTQVIESL
    ... ||.|. |.. |.  .. .|        |.. |         | .|   .         ..| .....  ..|| ||||.....| .
YGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase AqueK619.AA MLK 724-749 30 4e-06 17.28 In-house 266-291 (291) Show / Hide 
Range on Protein: 724-749
Range on HMM: 266-291/291
Sequence Identity: 30% (8 aa)

MKSLIQRGLKADPIDRPTMTQVIESL
.|.|...  ..|| .||.. |... |
WKKLMKQCWNQDPHKRPSFRQIVQHL
Kinase AqueK619.AA LRRK 715-751 27 1.4e-05 15.65 In-house 315-351 (351) Show / Hide 
Range on Protein: 715-751
Range on HMM: 315-351/351
Sequence Identity: 27% (10 aa)

QSGTVSWSDMKSLIQRGLKADPIDRPTMTQVIESLKR
. ... | ....|||   ..|| .||...|... |. 
CPPCQPWHMYQDLIQHCWQHDPKKRPHFSQIVKRLSQ
Kinase AqueK619.AA TKL-Unique 727-749 39 1.9e-05 15.34 In-house 268-290 (290) Show / Hide 
Range on Protein: 727-749
Range on HMM: 268-290/290
Sequence Identity: 39% (9 aa)

LIQRGLKADPIDRPTMTQVIESL
|||.. . || .||. ...|..|
LIQQCWHHDPSQRPSFDEIIHRL
Kinase AqueK619.AA Dicty4 725-751 34 0.000269 10.43 In-house 249-277 (277) Show / Hide 
Range on Protein: 725-751
Range on HMM: 249-277/277
Sequence Identity: 34% (10 aa)

KSLIQRGLKADPIDRPTMTQVIES--LKR
|.|||. .  ||. ||.. ..|.   |  
KHLIQWCWDHDPQHRPSFEEIIQRRILEH
Kinase AqueK619.AA HH498 726-749 33 0.004314 5.2 In-house 261-284 (284) Show / Hide 
Range on Protein: 726-749
Range on HMM: 261-284/284
Sequence Identity: 33% (8 aa)

SLIQRGLKADPIDRPTMTQVIESL
.|||..  . | .||.  |..  |
NLIQMCWHPCPENRPDFDQIVTIL
Kinase AqueK619.AA TK-Unique 723-749 25 0.044408 3.11 In-house 268-294 (294) Show / Hide 
Range on Protein: 723-749
Range on HMM: 268-294/294
Sequence Identity: 25% (7 aa)

DMKSLIQRGLKADPIDRPTMTQVIESL
.| .|... .. .| .||. .|..  |
EMYNLMKSCWQWEPEERPSFRQIKHRL
Kinase AqueK619.AA Pkinase_Tyr 721-749 31 0.200145 5.45 Pfam 242-270 (270) Show / Hide 
Range on Protein: 721-749
Range on HMM: 242-270/270
Sequence Identity: 31% (9 aa)

WSDMKSLIQRGLKADPIDRPTMTQVIESL
. .. .|...  ..|| ||||.....| |
PDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase AqueK619.AA Pkinase 722-749 30 0.261497 5.71 Pfam 264-293 (293) Show / Hide 
Range on Protein: 722-749
Range on HMM: 264-293/293
Sequence Identity: 30% (9 aa)

SDMKSLIQRGLKADPIDRPTMTQVIES--L
...|..| . |. || .||| .|. ..  .
EECKDFIKWCLCKDPKKRPTAEQILQHPWF