AqueK624

Species: A.queenslandica
Alias: AqueK624
External Links:
Annotation:

Classification

Group: TKL
Family: MLK
Subfamily: HH498

Sequence

Name Sequence Type Origin Length Description Download
AqueK624.AA Protein None 908 None Fasta, JSON
AqueK624.kin_dom Protein Kinase Domain None 78 None Fasta, JSON

Protein domain

Protein domains of AqueK624.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kelch_2 AqueK624.AA Kelch_2 16-68 18 0.007057 15.06 Pfam 5-51 (51) Show / Hide
Range on Protein: 16-68
Range on HMM: 5-51/51
Sequence Identity: 18% (10 aa)

HSTVRVGDYLYMWGGYQPDLPTVHNNEKKKSMCSVMEVCHLRTGRWEQKPTTG
|... .|. .|..|||        ..  . . .... .....| ||.  |  .
HASCVPGGKIYVFGGYC------RHTHNNDCWSMDIWWWDPETHRWTCVPRMP

Kelch_1 AqueK624.AA Kelch_1 12-68 14 13.8393 2.28 Pfam 1-45 (45) Show / Hide
Range on Protein: 12-68
Range on HMM: 1-45/45
Sequence Identity: 14% (8 aa)

EKKEHSTVRVGDYLYMWGGYQPDLPTVHNNEKKKSMCSVMEVCHLRTGRWEQKPTTG
    |. . .....|  ||. .            .  .  |. ...|..|.. |. .
PRCGHGVCVHNGKIYVIGGCDG------------QYLNSVECYDPETNQWTRCPPMP

Kelch_1 AqueK624.AA Kelch_1 73-120 20 1.3e-05 23.89 Pfam 1-45 (45) Show / Hide
Range on Protein: 73-120
Range on HMM: 1-45/45
Sequence Identity: 20% (10 aa)

GVMGYAAAAIGREIFYFGGWCYQGDCYHNSLYSFNVDTFNWKELSPTT
   |....... .|. .||..     | || ......|  |....| .
PRCGHGVCVHNGKIYVIGGCDG---QYLNSVECYDPETNQWTRCPPMP

Kelch_2 AqueK624.AA Kelch_2 73-120 19 0.001309 17.84 Pfam 1-51 (51) Show / Hide
Range on Protein: 73-120
Range on HMM: 1-51/51
Sequence Identity: 19% (10 aa)

GVMGYAAAAIGREIFYFGGW---CYQGDCYHNSLYSFNVDTFNWKELSPTT
. .. |.. .|  |. |||.    . .||...... .. .|  |.....  
PRYCHASCVPGGKIYVFGGYCRHTHNNDCWSMDIWWWDPETHRWTCVPRMP

Kelch_2 AqueK624.AA Kelch_2 129-193 9 4.244703 4.5 Pfam 1-51 (51) Show / Hide
Range on Protein: 129-193
Range on HMM: 1-51/51
Sequence Identity: 9% (6 aa)

SLCDMIAIKVNGEDYLVVIGGKGPSSNNTPPQPGAQYSGRVQQRCNEIHFYKLSTGQWISPTVTG
... .... .  .. ..|.||               ....   ... |... ..| .|   .. .
PRYCHASCVP--GGKIYVFGGYC------------RHTHNNDCWSMDIWWWDPETHRWTCVPRMP

Kelch_2 AqueK624.AA Kelch_2 254-299 23 0.004294 15.88 Pfam 1-51 (51) Show / Hide
Range on Protein: 254-299
Range on HMM: 1-51/51
Sequence Identity: 23% (13 aa)

GRNAHSSVLINTSSGPHLLVVGGY---------GAYDLWIFDINNKSWKKLDNLP
.|  |.|. .    |  ..|.|||            |.|..| . ..|...  .|
PRYCHASCVP----GGKIYVFGGYCRHTHNNDCWSMDIWWWDPETHRWTCVPRMP

Kelch_1 AqueK624.AA Kelch_1 265-299 15 0.020174 12.45 Pfam 8-45 (45) Show / Hide
Range on Protein: 265-299
Range on HMM: 8-45/45
Sequence Identity: 15% (6 aa)

TSSGPHLLVVGGYG---AYDLWIFDINNKSWKKLDNLP
.. . .. |.||.      . ...|  ...|... ..|
CVHNGKIYVIGGCDGQYLNSVECYDPETNQWTRCPPMP

Kelch_2 AqueK624.AA Kelch_2 305-350 23 5.376143 4.11 Pfam 1-32 (51) Show / Hide
Range on Protein: 305-350
Range on HMM: 1-32/51
Sequence Identity: 23% (11 aa)

RWFHSLSVGSVTPTTNWIIVFGGSSSYSDTAVIEFRYTSNNDWSTS
......|. .     ..|.||||..          |.| |||....
PRYCHASCVP----GGKIYVFGGYC----------RHTHNNDCWSM

Kinase AqueK624.AA TKL 516-598 20 8.1e-15 49.8 In-house 158-288 (364) Show / Hide
Range on Protein: 516-598
Range on HMM: 158-288/364
Sequence Identity: 20% (27 aa)

PHPILHRDVSSANVLLQ-----------PMIGVWRAKVSDYGSANLQHSI---------------------IRSVNPGGPLYAAPEAANPR---------
. ||.|||  |.|.|.            . .  |..|..|.| .   .                        ..   | | . |||. .           
KPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGI

-------EHSPSMDVFSYGVLLLEMITQRIP
       | |...||.|.|..| |..| ..|
DEFCKGFEYSEKCDVYSFGIVLWEILTRCRP

Kinase AqueK624.AA LRRK 518-598 26 2.3e-09 29.28 In-house 186-282 (351) Show / Hide
Range on Protein: 518-598
Range on HMM: 186-282/351
Sequence Identity: 26% (26 aa)

PILHRDVSSANVLLQPMI---------GVWRAKVSDYGSAN----LQHS-IIRSVNPGGPLYAAPEAANPR---EHSPSMDVFSYGVLLLEMITQR-IP
||.|||  | |.||. .              ||..|.|       .... . ..| .  |.. |||  .     | .   |..|.|..| | .| . .|
PIIHRDLKSPNILLWSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMGVAKGCVGN--PGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHP

Kinase AqueK624.AA TKL-Unique 518-598 28 6.9e-09 27.66 In-house 132-233 (290) Show / Hide
Range on Protein: 518-598
Range on HMM: 132-233/290
Sequence Identity: 28% (29 aa)

PILHRDVSSANVLLQPM--IGVWRAKVSDYGSANLQHSIIRSVNP-----------GGPLYAAPEAANP--REHSPSMDVFSYGVLLLEMITQRI-----
||.|||  | |.|.     |  |..|..| | . .. .|... |            | ....|||  .      | . ||.|.|. | |..|  |     
PIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLRMNFCQYSEKSDVYSFGIVLWEIATRKITKTYK

-P
 |
KP

Kinase AqueK624.AA MLK 516-598 31 8.3e-09 26.81 In-house 145-235 (291) Show / Hide
Range on Protein: 516-598
Range on HMM: 145-235/291
Sequence Identity: 31% (29 aa)

PHPILHRDVSSANVLLQP---MIGVWRAKVSDYGSANLQHSI-I-RSVNPGGPLYAAPEA---ANPREHSPSMDVFSYGVLLLEMITQRIP
|.|| |||  | |.|.      ..   .|..| | .   |..   .  |.| . . |||.   .     | . ||.|.||.| ||.| ..|
PKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMMSNAGTYAWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVP

Kinase AqueK624.AA STE 517-602 24 1.9e-08 26.08 In-house 171-271 (359) Show / Hide
Range on Protein: 517-602
Range on HMM: 171-271/359
Sequence Identity: 24% (27 aa)

HPILHRDVSSANVLLQPMIGVWRAKVSDYGSAN-LQHSII-----------------RSVNPGGPLYAAPEAANP------REHSPSMDVFSYGVLLLEM
| | |||. .||.||        .| .| | .  |..|.                  |    | | . |||  ..       ... . |. | | ...||
HHIIHRDIKPANILL--------VKLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEM

ITQRIPLPEE
.| . |. ..
ATGKPPWHDM

Kinase AqueK624.AA STE-Unique 518-595 17 2.6e-08 25.02 In-house 425-549 (616) Show / Hide
Range on Protein: 518-595
Range on HMM: 425-549/616
Sequence Identity: 17% (22 aa)

PILHRDVSSANVLLQP--MIGVWRAKVSDYGSANLQHSI----------------------------------------IRSVNPGGPLYAAPEAANPR-
||.|||. ..|...       | ..|..|.| |.    .                                        ..  ..| | | .||  | | 
PIIHRDLKPHNIFCMQDGKGRVCKVKICDFGHATCCQPDHFEKDNNSKNSNTWININNNSSTNSTAQQTPMWDLNINNYTMKYCCGTPCYMCPEVINCRN

----EHSPSMDVFSYGVLLLEMITQ
    ...   |..| | ....|...
QINNPYDTKVDIWSLGCMCFHMCCG

Kinase AqueK624.AA TK 519-594 19 3.2e-08 22.85 In-house 261-389 (486) Show / Hide
Range on Protein: 519-594
Range on HMM: 261-389/486
Sequence Identity: 19% (25 aa)

ILHRDVSSANVLLQ-PMIGVWR-------AKVSDYGSAN-----LQHSI------IRSVNPGGPL-------------------------YAAPEAAN--
. |||.   |.|.   ..  |        .|..|.| .      |   |       |. ..|...                         . |||. |  
FVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDR

-------PREHSPSMDVFSYGVLLLEMIT
        . ...  ||.|.|||. |. |
VFSEAEKYGKFTTKSDVWSFGVLMWEIFT

Kinase AqueK624.AA Dicty5 519-598 30 5.4e-08 23.61 In-house 125-202 (260) Show / Hide
Range on Protein: 519-598
Range on HMM: 125-202/260
Sequence Identity: 30% (25 aa)

ILHRDVSSANVLLQPMIGVWRAKVSDYG-SANLQHSIIRSVNPGGPLYAAPEAANPREHSPSMDVFSYGVLLLEMITQRIP
| |||. | |.|.      | .|. |.| | .        .. | . . |.|  | .      ||.|.|. | ||.|.  |
IIHRDLKSMNFLITEN---WKIKIIDFGTSRFVDNRYHMTMHVGTQCWMACELFNGQPYHQKCDVYSFGIVLWEMFTRKEP

Kinase AqueK624.AA Ciliate-E2 518-598 20 1.2e-07 22.28 In-house 181-295 (365) Show / Hide
Range on Protein: 518-598
Range on HMM: 181-295/365
Sequence Identity: 20% (25 aa)

PILHRDVSSANVLLQPMIGVWRAKVSDYGSAN-----------LQHSIIRSVNP-----------------------GGPLYAAPEAANPRE--------
.|.|||    |.|.         |..| | .            .|.. .                            | | | |||  |  .        
NIIHRDIKPENILF--------IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQK

-HSPSMDVFSYGVLLLEMITQRIP
 .. . |..| ||.| ||.. . |
GYDYKCDIWSLGVILYEMLFGKPP

Kinase AqueK624.AA Pkinase 517-625 25 7.9e-07 25.22 Pfam 127-236 (293) Show / Hide
Range on Protein: 517-625
Range on HMM: 127-236/293
Sequence Identity: 25% (29 aa)

HPILHRDVSSANVLLQ--PMIGVWRAKVSDYGSAN---LQHSIIRSVNPGGPLYAAPEAAN-PREHSPSMDVFSYGVLLLEMITQRIPLPEERVGLIDVL
. |.|||. ..|.|.   . |.  . |..| |.|    . ..   ..  | | |.|||  .  ....|. |..|.|..| ||.. | | |..  . .. .
MGIIHRDLKPENILIDNNGHIDA-CVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHC-WHDN-H

KQSFKYDVIIRALPP
 | .... | .. ..
DQMQMICRIMGPPLH

S_TKc AqueK624.AA S_TKc 380-755 11 4e-06 -87.29 SMART 1-220 (231) Show / Hide
Range on Protein: 380-755
Range on HMM: 1-220/231
Sequence Identity: 11% (46 aa)

REIDRLI------RVLQERERELEEERREKEQVRNRLQQQLQGREQQLQQAQQQGQEREREIQQAREQVQDLQRQLQERERQLHQAEQQLQSREREAQER
 || |.|      .| . |...  ..   |.                                           .  .||.|...              .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----------------------------------------EHIRREIQILKK-------------H

EQQLQRQVEGGQQREQDLQRQLQQAQQ---QLRERDRQER-------ESSWV----------------PHPILHRDVSSANVLLQPMIGVWRAKVSDYGS
   . .  .  |   ..|   .  . .    |... .. .        .  .                 | |.|||.  .|.||       . |..| |.
HPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGL

ANLQHSIIRSVNPGGPLYAAPEAANPREHSP-SMDVFSYGVLLLEMITQRIPLPEERVGLIDVLKQSFKYDVIIRALPPNKMAAKAAPDYQPVERSGHST
| .      .   | | | |||      ... . |. | |..| ||.. . | | .   ......                                   
ARQL-----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP-QMQMMFKKIG-----------------------------------

VRTTSKNMRAHKPKAVLGLNLKGVSLYDERSKSITRVPVDKVTYVTHDPEDQCYFGVIIQTKESHTGFRLYCFKAKRPIAVTFVNSSLELFDLIMKLRQA
                                                                                      | |. |.|.|. | 
--------------------------------------------------------------------------------------SPEAKDFIRKCLQK

KKK----MKEEKE
  .      |  .
DPEKRPTA-EALQ

Kinase AqueK624.AA CZAK 514-546 37 9e-06 17.1 In-house 125-167 (279) Show / Hide
Range on Protein: 514-546
Range on HMM: 125-167/279
Sequence Identity: 37% (16 aa)

WVPHPILHRDVSSANVLLQPMIG----------VWRAKVSDYG
| | |||||| || |.||   .              .|..|.|
WKPNPILHRDLSSRNILLDHSYTPKNPVVSSRQDIICKINDFG

Kinase AqueK624.AA PTB 580-750 15 0.000136 14.8 SMART 1-156 (156) Show / Hide
Range on Protein: 580-750
Range on HMM: 1-156/156
Sequence Identity: 15% (29 aa)

MDVFSYGVLLL---EMITQR-IPLPEERVGLIDVLKQSFKYDVIIRALPPNKMAAKAAPDYQPVERSGHSTVRTTSKNMRAHKPKAVLGLNLKGVSLYDE
 .. .. |. |   |.   |  ..|. .. ... . . ..                                      .. |. | .| .  .||.| |.
PWGCCFNVWYLGCVEVPHHRNSMAPGKGMQVCQECMRKIR-------------------------------------QHWKHWQKMHLHISVDGVKLIDP

RSK-SITRVPVDKVTYVTHDP-----------EDQCYFGVIIQTKESH------TGFRLYCFKAKRPIAVTFVNSSLELFDLIMKLRQAKKKM
 .|  | . |. ..... |||           .| ..||.|.  . ..      . ||...|. . | |   . . ...|.......|.... 
QTKQVIHHHPIHRISFCAHDPYRWNTGGHHCCDDDRCFGYICRHPNDRGSHRMTYWFRCHVFWCEDPHAEDIAQTIGQAFQVCYQQCQKQRCQ

Kinase AqueK624.AA CZAK 565-598 32 0.012478 5.56 In-house 188-221 (279) Show / Hide
Range on Protein: 565-598
Range on HMM: 188-221/279
Sequence Identity: 32% (11 aa)

YAAPEAANPREHSPSMDVFSYGVLLLEMITQRIP
. |||       ..  ||.|.| .| ..|| . |
WMAPECFKGENYTEKVDVYSFGMILWCIITCDQP