Gene AqueK631 (A.queenslandica)

AqueK631

Species: A.queenslandica
Alias: AqueK631
External Links:
Annotation:

Classification

Group: TKL
Family: MLK
Subfamily: HH498

Sequence

Name Sequence Type Origin Length Description Download
AqueK631.AA Protein None 1470 None Fasta, JSON
AqueK631.kin_dom Protein Kinase Domain None 158 None Fasta, JSON

Protein domain

Protein domains of AqueK631.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase AqueK631.AA TKL 597-755 17 9.2e-30 104.34 In-house 125-364 (364) Show / Hide 
Range on Protein: 597-755
Range on HMM: 125-364/364
Sequence Identity: 17% (43 aa)

LRRNRLTNQQILSIAQDVALGLNYLHLFKP-----QPIIHRDVSSPNVLLKPCTRP---------AGFEAKVADYGTAKLVQVDS---------------
|. . .  .|....|.|.|.|.||||  .|      ||||||  |.|.|..   ..         |   .|..|.|... .. ..               
LLHYLH-WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEH

-----TGTVMPGNVAYAAPEARDPD----------------QHSPAMDVYSYSVLLMEMTLGSPPEMTMAEREVQ---------AGSV------------
     |     |. .. |||. . .                . |...||||. ..| |.  . .|.  . .....         .. .            
QNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIW

-----------SWSDMKSLIQIGINASPRARLTMAQAKSFM
            . .||.|.|   .. |..|... . .. .
QNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase AqueK631.AA MLK 605-705 32 5.2e-22 73.24 In-house 124-229 (291) Show / Hide 
Range on Protein: 605-705
Range on HMM: 124-229/291
Sequence Identity: 32% (34 aa)

QQILSIAQDVALGLNYLHLFKPQPIIHRDVSSPNVLLKP-CTRPAGFEAKVADYGTAKLVQVD-STGTVMPGNVAYAAPEAR---DPDQHSPAMDVYSYS
......| ..| |..|||  .|.||||||  |.|.|.   |   ..  .|..| ||.. ..   .. . ..|..|. |||..     .. | . ||.|. 
DHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMMSNAGTYAWMAPEVIQQFRCEKYSEKCDVWSWG

VLLMEM
|.| ||
VVLWEM
Kinase AqueK631.AA CZAK 608-705 30 1.7e-17 60.19 In-house 108-215 (279) Show / Hide 
Range on Protein: 608-705
Range on HMM: 108-215/279
Sequence Identity: 30% (33 aa)

LSIAQDVALGLNYLHL-FKPQPIIHRDVSSPNVLLKPCTR--------PAGFEAKVADYGTAKLVQVDSTG-TVMPGNVAYAAPEARDPDQHSPAMDVYS
...| |.| | ||||  .|| ||.||| || |.||                  .|..|.|  ..     .  |   | ... |||    .  ..  ||||
WNMAIDIARGMNYLHDNWKPNPILHRDLSSRNILLDHSYTPKNPVVSSRQDIICKINDFGLSREMMEQPFEMTQTMGCLCWMAPECFKGENYTEKVDVYS

YSVLLMEM
.  .| ..
FGMILWCI
Kinase AqueK631.AA TKL-Unique 602-705 31 5.4e-17 56.61 In-house 107-221 (290) Show / Hide 
Range on Protein: 602-705
Range on HMM: 107-221/290
Sequence Identity: 31% (37 aa)

LTNQQILSIAQDVALGLNYLHLFKPQPIIHRDVSSPNVLLKPCTRPAGFEAKVADYGTAKLVQVDSTGTVM----------PGNVAYAAPEARDP--DQH
|..||....|.|.|.|..|||  .|  |||||  |.|.|.      | . .|..| |..|.   ....|.            |.  ..|||      .| 
LNMQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLRMNFCQY

SPAMDVYSYSVLLMEM
|   ||||... | |.
SEKSDVYSFGIVLWEI
Kinase AqueK631.AA TK 574-755 12 9.3e-15 45.15 In-house 87-486 (486) Show / Hide 
Range on Protein: 574-755
Range on HMM: 87-486/486
Sequence Identity: 12% (51 aa)

KEMGIASRVR-----HPNLVQFIG-ATKE----------------------------------LRRNR--------------------------------
.|. ...  .     |||.|...|  |..                                  ||..|                                
EEAEEMKMMCHSLGHHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITY

---------------------------------------------LTNQQILSIAQDVALGLNYLHLFKP---QPIIHRDVSSPNVLLKPCTR------P
                                             || .| | .....| |. |||  .    | ..|||.   |.|.    .       
SHESNSPCPEEQDYDDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDG

AGFEAKVADYG--------TAKLVQVDSTGTVMPGN---------------------------VAYAAPEARD---------PDQHSPAMDVYSYSVLLM
 |. .|.||.|         |. .. |.  ... .                            . . |||. .            .... ||.|. ||. 
CGPVCKIADFGLSRQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMW

EMT-LG-SPPE--MTM---------------------------------AEREVQAGSVSW------------SDMKSLIQIGINASPRARLTMAQAKSF
|.  .|  |.   |.                                   ...  ..  .|             ..  |.|   .. |. | |..| ...
EIFTYGQEPYYGGMSNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQ

M
.
L
Kinase AqueK631.AA HH498 605-705 38 1.8e-14 41.93 In-house 121-219 (284) Show / Hide 
Range on Protein: 605-705
Range on HMM: 121-219/284
Sequence Identity: 38% (40 aa)

QQILSIAQDVALGLNYLHLFKPQPIIHRDVSSPNVLLKPCTRPAGFEAKVADYGTAKLVQV--DSTGTVMPGNVAYAAPEARD-PDQHSPAMDVYSYSVL
| .. |. ||| | ||||   ..||||||  | |.|.    .     |.|||.|    |.   | . |  |||  . |||      . |   ||.||   
QSKMTISVDVAHGMNYLHNSLKHPIIHRDLNSHNILIHEDGH-----AVVADFGESRFVCDMHDDNMTKQPGNLRWMAPEVFSQCQKYSIKVDVFSYAMC

LMEM
. ||
IWEM
S_TKc AqueK631.AA S_TKc 547-760 18 2.9e-14 32.22 SMART 1-231 (231) Show / Hide 
Range on Protein: 547-760
Range on HMM: 1-231/231
Sequence Identity: 18% (47 aa)

ILTKEELGRGSYAIVTVGIFQG--LRVVVK--------EMGIASRVRHPNLVQFIGATK------------E--------LRRNR-------LTNQQILS
    ...|.|... |  ..  .   .| .|        |. | .. .|||.|.....                       .....       ..  .. .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIKEHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARF

IAQDVALGLNYLHLFKPQPIIHRDVSSPNVLLKPCTRPAGFEAKVADYGTAKLVQVDSTGTVMPGNVAYAAPEARDPDQHSP-AMDVYSYSVLLMEMTLG
... ....|.|.|  .   |||||.   |.||         . |..| | |...      | . |   | |||     .... . |..|  ..| ||  |
YMYQICCALEYCHSHG---IIHRDLKPENILLDE-------HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCG

SPPEMTMAEREVQAGSVSWSDMKSLIQIGINASPRARLTMAQAKS----FMARPRL
 ||     ..  .      ...|..|.   .  |. |.|  .|       .. | .
YPPFP-QMQMMFKKIG--SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK631.AA Dicty4-Unclassified 607-711 30 3.4e-14 44.97 In-house 111-207 (263) Show / Hide 
Range on Protein: 607-711
Range on HMM: 111-207/263
Sequence Identity: 30% (32 aa)

ILSIAQDVALGLNYLHLFKPQPIIHRDVSSPNVLLKPCTRPAGFEAKVADYGTAKLVQVDSTGTVMPGNVAYAAPEARDPDQHSPAMDVYSYSVLLMEMT
|. .| |.| |. .||      .||||. | |.|.        | .|.|| | .  .    . |   | ..  .||         . ||||| ..| |. 
IIKYAFDIAQGMQHLHTRN---FIHRDIKSSNILMD-----KHFNIKIADFGISRVIDFNFNMTTIAGTPKWESPECLMHESYNQKSDVYSYAMMLYELA

LGSPP
 |  |
TGDEP
Kinase AqueK631.AA LZK 599-705 34 2.2e-13 41.4 In-house 81-180 (241) Show / Hide 
Range on Protein: 599-705
Range on HMM: 81-180/241
Sequence Identity: 34% (37 aa)

RNRLTNQQILSIAQDVALGLNYLHLFKPQPIIHRDVSSPNVLLKPCTRPAGFEAKVADYGTAKLVQVD-STGTVMPGNVAYAAPEARDPDQHSPAMDVYS
|. .| | . .  ...| |..|||. |   |||||  |||.|       .    |..|.|| .  .   ||     | ||  |||    .  |   |..|
RRTITPQLMVDWSKQIAQGMHYLHQHK---IIHRDLKSPNILIS-----HNDVVKICDFGTSHMWNEMDSTKMSFCGTVAWMAPEVIRNEPCSEKVDIWS

YSVLLMEM
. | | ||
FGVVLWEM
Kinase AqueK631.AA TK-Unique 598-711 27 2.7e-13 42.29 In-house 124-239 (294) Show / Hide 
Range on Protein: 598-711
Range on HMM: 124-239/294
Sequence Identity: 27% (33 aa)

RRNRLTNQQILSIAQDVALGLNYLHLFKPQPIIHRDVSSPNVLLKPCTRPAGFEAKVADYGTAKLVQ----VDSTGTVMPGNVAYAAPEA-R--DPDQHS
|.. .. .. ...| ..| |..||.   .. |.|||... ||||       ....|..|.| |. |.    ......  .  ... |||. .  .   |.
RTEPISPKDLYHFAWQIACGMEYLASQ-RKKIVHRDLCARNVLLTE-----DKVCKICDFGMARDVYTNGVYSMMCSQGRIPIRWMAPESLKCYHGMYHT

PAMDVYSYSVLLME-MTLGSPP
.  ||.|. ||. | .|||..|
TKSDVWSFGVLMWEIFTLGACP
Kinase AqueK631.AA LRRK 586-702 30 3.3e-13 43.07 In-house 141-272 (351) Show / Hide 
Range on Protein: 586-702
Range on HMM: 141-272/351
Sequence Identity: 30% (40 aa)

NLVQFIGATKELRR----NRLTNQQILSIAQDVALGLNYLHLFKPQPIIHRDVSSPNVLLKPCTRP-------AGFEAKVADYGTAKLVQVDSTG--TVM
.| .|. ..|. ..     ... . .| || ..| |..||| ..| ||||||  |||.||.  . .       |   ||.||.|.  . |.. .|    .
DLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNP-PIIHRDLKSPNILLWSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMGVAKGC

PGNVAYAAPEARDPD---QHSPAMDVYSYSVLL
 ||  . ||| .  .   . .   |.||. ..|
VGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMIL
Kinase AqueK631.AA TyrKc 547-755 19 5.8e-13 -13.15 SMART 1-280 (280) Show / Hide 
Range on Protein: 547-755
Range on HMM: 1-280/280
Sequence Identity: 19% (55 aa)

ILTKEELGRGSYAIVTVGIFQGLRVVVKEMG------------IASRV--RHPNLVQFIGATKE--------------------------LRRNR--LTN
|  ...||.| . .|  |.   . | || .             | ...  .|||.|...|.  .                          ||..|  |..
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKLCM

QQILSIAQDVALGLNYLHLFKPQPIIHRDVSSPNVLLKPCTRPAGFEAKVADYGTAKLVQVD-------STGTV-----MP--GNVAYAAPEARDPDQHS
.. ||.. ..| | .|||     ..||||    |.|..         .|..| | .. .  |       .. ..           .   |||. .    .
KDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENH-----TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

PAMDVYSYSVLLMEM-TLGSPPE-------MTMAE--REVQAG------SV--------SWSDMKSLIQIGINASPRARLTMAQAKSFM
.. ||.|. |.. |. |.| .|        |. .|  . |..|                  ..| ....   .. |  | |... ....
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase AqueK631.AA Pkinase 598-711 29 5.3e-09 32.92 Pfam 99-211 (293) Show / Hide 
Range on Protein: 598-711
Range on HMM: 99-211/293
Sequence Identity: 29% (35 aa)

RRNRL--TNQQILSIAQDVALGLNYLHLFKPQPIIHRDVSSPNVLLK-PCTRPAGFEAKVADYGTAKL--VQVDSTGTVMPGNVAYAAPEA-RDPDQHSP
|....  . ... ...  .. ||.|.|      |||||. . |.|..  .. .|    |..| | ||.     .|  |.  |   |.|||  |.   ..|
RHGCFYFSEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDA--CVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGP

AMDVYSYSVLLMEMTLGSPP
. |..|. ..| || .| ||
KVDMWSCGCILYEMLCGRPP
Kinase AqueK631.AA Pkinase_Tyr 597-705 24 7.2e-08 27.27 Pfam 98-207 (270) Show / Hide 
Range on Protein: 597-705
Range on HMM: 98-207/270
Sequence Identity: 24% (29 aa)

LRRN-----RLTNQQILSIAQDVALGLNYLHLFKPQPIIHRDVSSPNVLLKPCTRPAGFEAKVADYGTAKLVQVDSTG-TVMP---GNVAYAAPEARDPD
||..     .|| ...|......| |..||.  .   .||||.   |.|..      .. .|..| | |.... |..  ..       .   |||.    
LRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKN---CIHRDLAARNCLVT-----ENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYG

QHSPAMDVYSYSVLLMEM
  . . ||.|. ||. |.
KFTTKSDVWSFGVLMWEI
Kinase AqueK631.AA TKL 553-596 18 1.5e-07 23.23 In-house 1-96 (364) Show / Hide 
Range on Protein: 553-596
Range on HMM: 1-96/364
Sequence Identity: 18% (18 aa)

LGRGSYAIVTVGIFQG----------LRVVVKEMG------------------------------------------IASRVRHPNLVQFIGATKE
.|.|....|  |...|            |.|| .                                           . || ||||.|||.|. ..
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCC
Kinase AqueK631.AA CZAK 574-593 60 1.1e-05 16.8 In-house 49-68 (279) Show / Hide 
Range on Protein: 574-593
Range on HMM: 49-68/279
Sequence Identity: 60% (12 aa)

KEMGIASRVRHPNLVQFIGA
|| .| |  .||| |||.||
KEVSIMSKLCHPNCVQFLGA
Kinase AqueK631.AA MLK 547-596 20 0.001122 8.78 In-house 1-80 (291) Show / Hide 
Range on Protein: 547-596
Range on HMM: 1-80/291
Sequence Identity: 20% (16 aa)

ILTKEELGRGSYAIVTVGIFQGLR-----VVVKEMG---------------------IASRVRHPN----LVQFIGATKE
|...| .| ||.  |  | ... .     | ||.                       ......|||     .|| |. ..
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQ
Kinase AqueK631.AA TKL-Unique 574-595 26 0.011073 5.5 In-house 44-66 (290) Show / Hide 
Range on Protein: 574-595
Range on HMM: 44-66/290
Sequence Identity: 26% (6 aa)

KEMGIASRVR-HPNLVQFIGATK
.|  . .. . |||.|...|...
NEVNWMKKLHYHPNIVHYMGYCM
Kinase AqueK631.AA LRRK 547-576 29 0.094151 1.96 In-house 1-31 (351) Show / Hide 
Range on Protein: 547-576
Range on HMM: 1-31/351
Sequence Identity: 29% (9 aa)

ILTKEELGRGSYA-IVTVGIFQGLRVVVKEM
.   |..|||... .|  ....|  | |..|
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRM
Kinase AqueK631.AA Dicty4-Unclassified 547-574 32 0.209503 0.53 In-house 1-28 (263) Show / Hide 
Range on Protein: 547-574
Range on HMM: 1-28/263
Sequence Identity: 32% (9 aa)

ILTKEELGRGSYAIVTVGIFQGLRVVVK
|    ..|.|  . |  |.  |  | ||
IQIDQFIGKGHFSKVHKGNWKGKDVAVK
Kinase AqueK631.AA Pkinase 547-561 26 6.232918 0.84 Pfam 1-15 (293) Show / Hide 
Range on Protein: 547-561
Range on HMM: 1-15/293
Sequence Identity: 26% (4 aa)

ILTKEELGRGSYAIV
. ... .|.||.. |
YHIGRKIGSGSFGCV
Kinase AqueK631.AA Pkinase_Tyr 583-593 45 7.653163 0.09 Pfam 62-72 (270) Show / Hide 
Range on Protein: 583-593
Range on HMM: 62-72/270
Sequence Identity: 45% (5 aa)

RHPNLVQFIGA
.|||.|...|.
HHPNIVRLYGV