Gene AqueK636 (A.queenslandica)

AqueK636

Species: A.queenslandica
Alias: AqueK636
External Links:
Annotation:

Classification

Group: TKL
Family: MLK
Subfamily: HH498

Sequence

Name Sequence Type Origin Length Description Download
AqueK636.AA Protein None 1369 None Fasta, JSON
AqueK636.kin_dom Protein Kinase Domain None 193 None Fasta, JSON

Protein domain

Protein domains of AqueK636.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase AqueK636.AA TKL 505-737 19 7.8e-45 155.27 In-house 1-360 (364) Show / Hide 
Range on Protein: 505-737
Range on HMM: 1-360/364
Sequence Identity: 19% (71 aa)

LGRGSYAAVTVGIFRG----------LRVAVKSLHNIIISDFNL-------------------------ALFSREMDIASRVRHPNLVQFIGATKVDN--
.|.|... |  |..||            |||| ..    . |..                           . .|. . || ||||.|||.|. .  .  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------PLILTELM-STSLNQELHRNQLTNQQILSIAQDVALGLNYLHLFKP-----QAIIHRDISSPNVLLKPCTGP---------AGYEAKV
            . | .|..   ||   ||      .|....|.|.|.|.||||  .|      .|||||. |.|.|..    .         | . .|.
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-----WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKI

SDYGTAKVVQAEN--------------------TGTVMPGNVAYAAPEAPIPD----------------QHSPAMDVYSYSVLLMEMNLCSRPEMTTAKR
.|.|...... ..                    |     |. .. |||.   .                . |...||||. ..| |.  . ||.     .
CDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPYM

DVQ---------SGSV-----------------------SWSDMKSLIQRGLNANPRARPTMAQV
...         .. .                        . .||.|.|.  ...|..||.. ..
PMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEI
Kinase AqueK636.AA MLK 499-691 26 4.4e-35 119.18 In-house 1-229 (291) Show / Hide 
Range on Protein: 499-691
Range on HMM: 1-229/291
Sequence Identity: 26% (61 aa)

ILTKEELGRGSYAAVTVGIFRGLR-----VAVKSLHNIIISDFNLA-----LFSREMDIASRVRHPN----LVQFIGATKVD-N-PLILTELMST-SLNQ
|...| .| ||. .|  | .|. .     ||||  .  |. |   .      | .|  ......|||     .|| |. . . .  .|..| ..  ||. 
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYN

ELHRNQ---------------LTNQQILSIAQDVALGLNYLHLFKPQAIIHRDISSPNVLLKP-CTGPAGYEAKVSDYGTAKVVQAE-NTGTVMPGNVAY
 || ..                . ......| ..| |..|||  .|..|||||. |.|.|.   |   ..  .|..| ||.. ..    . . ..|..|.
VLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMMSNAGTYAW

AAPEAP---IPDQHSPAMDVYSYSVLLMEM
 |||.      .. | . ||.|. |.| ||
MAPEVIQQFRCEKYSEKCDVWSWGVVLWEM
Kinase AqueK636.AA TKL-Unique 501-691 29 7.5e-32 109.67 In-house 1-221 (290) Show / Hide 
Range on Protein: 501-691
Range on HMM: 1-221/290
Sequence Identity: 29% (65 aa)

TKEELGRGSYAAVTVGIFRGLRVAVKSLHNIIISDFNLA---LFSREMDIASRVR-HPNLVQFIGATK---VDNP--LILTELMST-SLNQELH------
  . .|.|.|..|  |..||  ||.|..|.   .|...     |..|  . .. . |||.|...|...   |..|   | .| ..  ||.  ||      
FWNKIGEGGYGQVYKGKWRGYPVAIKQFHP--NEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNN

-----RNQLTNQQILSIAQDVALGLNYLHLFKPQAIIHRDISSPNVLLKPCTGPAGYEAKVSDYGTAKVVQAENTGTVM----------PGNVAYAAPEA
      . |..||....|.|.|.|..|||  .|  |||||. |.|.|.      | . .|..| |..|.   .|..|.            |.  ..||| 
NNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEV

PIP--DQHSPAMDVYSYSVLLMEM
     .| |   ||||... | |.
LRMNFCQYSEKSDVYSFGIVLWEI
Kinase AqueK636.AA TK 499-691 14 1.6e-27 88.72 In-house 1-387 (486) Show / Hide 
Range on Protein: 499-691
Range on HMM: 1-387/486
Sequence Identity: 14% (56 aa)

ILTKEELGRGSYA---AVTVGIFRGL---------------------------RVAVKSLH---NIIISDFNLALFS---------REMDIASRVR----
|   ..||.| .     |  |. ||.                           .|||| |.   .    .| .. .          .|. ...  .    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HPNLVQFIG-ATKVDN------------PLILTELMS-TS----LNQELHRN-----------------------------------------------
 |||.|...|  |....            ..|..|.|.  .    | . |...                                               
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

------------------------------QLTNQQILSIAQDVALGLNYLHLFKP---QAIIHRDISSPNVLLKPCTG------PAGYEAKVSDYG---
                              ||| .| | .....| |. |||  .    | ..|||.   |.|.             |. .|..|.|   
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----TAKVVQAENTGTVMPGN---------------------------VAYAAPEAPI---------PDQHSPAMDVYSYSVLLMEM
      |. .. .   ... .                            . . |||.              .... ||.|. ||. |.
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEI
Kinase AqueK636.AA Dicty4 499-691 30 3.4e-27 87.87 In-house 1-210 (277) Show / Hide 
Range on Protein: 499-691
Range on HMM: 1-210/277
Sequence Identity: 30% (65 aa)

ILTKEELGRGSYAAVTVGIFRGLRVAVKSL--HNIIISDFNLALFSREMDIASRVRHPNLVQFIGA-T----KVDNPLILTELM-STSLNQELHR-----
| . ...|.||.. |  |. ||  |||| |  ||.  . . |  | .| .| .  ||||...| || |    .   ..| ||.| ...|   ||      
INIEQRIGKGSFGEVYKGTWRGKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSEQ

-NQLTNQ--QILS---IAQDVALGLNYLHLFKPQAIIHRDISSPNVLLKPCTGPAGYEAKVSDYGTAKVVQAENTGTV----MPGNVAYAAPEAPIPDQH
    . .   |..   .| |.|.|.|.||   |  |||||. | | |       . . .||.| | ... . . . .     . | ... |||    .  
QQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPV-IIHRDLKSHNLLVD-----KNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPY

SPAMDVYSYSVLLMEM
  . ||||.. .| |.
NEKADVYSFGIVLWEI
Kinase AqueK636.AA S_TKc 499-740 18 4.7e-25 90.49 SMART 1-231 (231) Show / Hide 
Range on Protein: 499-740
Range on HMM: 1-231/231
Sequence Identity: 18% (50 aa)

ILTKEELGRGSYAAVTVGIFRG--LRVAVKSLHNIIISDFNLALFSREMDIASRVRHPNLVQFIGATKVDNPLILTELMST---SLNQELHRNQ------
    ...|.|... |  .. ..   .||.| ..           . ||..| .. .|||.|.....   |.  . .|....   .| . .....      
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-LTNQQILSIAQDVALGLNYLHLFKPQAIIHRDISSPNVLLKPCTGPAGYEAKVSDYGTAKVVQAENTGTVMPGNVAYAAPEAPIPDQHSP-AMDVYSYS
 ..  .. .... ....|.|.|  .   |||||.   |.||         . |..| | |...      | . |   | |||     .... . |..|  
PFPE-HARFYMYQICCALEYCHSHG---IIHRDLKPENILLDE-------HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCG

VLLMEMNLCSR---PEMTTAKRDVQSGSVSWSDMKSLIQRGLNANPRARPTMAQVRG----------V
..| ||         .... |. .       ...|..|.. |. .|. |||  ..            .
CILYEMLCGYPPFPQMQMMFKKIG------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK636.AA CZAK 500-691 29 1.5e-24 86.18 In-house 1-215 (279) Show / Hide 
Range on Protein: 500-691
Range on HMM: 1-215/279
Sequence Identity: 29% (64 aa)

LTKE-ELGRGSYAAVTVGIFRGLRVAVKSLHNIIISDFNL----ALFSREMDIASRVRHPNLVQFIGATKVDN---PLILTELMS-TSLNQEL-HRNQLT
|. . . |.| .  |  .  ||  ||.| .| .   .         | .|  | |  .||| |||.||   |.     | .| |   || . |  .  . 
LKFGQTIGQGFFGEVYKAYWRGKDVAIKIIHRNQFRNKDENKEENMFQKEVSIMSKLCHPNCVQFLGACSEDGPNHHCIVMEWMGGGSLRRLLTDHYFYH

NQ---QILSIAQDVALGLNYLHL-FKPQAIIHRDISSPNVLLKPCTG--------PAGYEAKVSDYGTA---KVVQAENTGTVMPGNVAYAAPEAPIPDQ
 |     ...| |.| | ||||  .||  |.||| || |.||                  .|..|.|     .    | | |.  | ... |||  . . 
KQNPHLQWNMAIDIARGMNYLHDNWKPNPILHRDLSSRNILLDHSYTPKNPVVSSRQDIICKINDFGLSREMMEQPFEMTQTM--GCLCWMAPECFKGEN

HSPAMDVYSYSVLLMEM
 ..  ||||.  .| ..
YTEKVDVYSFGMILWCI
Kinase AqueK636.AA STE 500-668 17 5.6e-22 74.47 In-house 1-232 (359) Show / Hide 
Range on Protein: 500-668
Range on HMM: 1-232/359
Sequence Identity: 17% (44 aa)

LTK-EELGRGSYAAVTVGIFR-----------------GLRVAVKSLH---------------NIIISDFNLALFSREMDIASRVR--HPNLVQFIGATK
... |..|.|..  |  .. .                 | ..|.| ..               . .. . ..  . .|..| .. .  ||| |...|.  
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

VD--------NPLILTELMS-TSLNQELHRN-----QLT----------NQQILSIAQDVALG-LNYLHLFKPQAIIHRDISSPNVLLKPCTGPAGYEAK
..        .  |  |.|.  || . ....     .|.           .||  |....  | |.|||  .   |||||| . |.||          .|
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH---IIHRDIKPANILL----------VK

VSDYGTAKVVQAENTGT-----------------VMPGNVAYAAPE
 .| |... .. ....                   . |   . |||
LCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPE
Kinase AqueK636.AA DRK 499-626 38 5.7e-21 67.79 In-house 1-132 (258) Show / Hide 
Range on Protein: 499-626
Range on HMM: 1-132/258
Sequence Identity: 38% (51 aa)

ILTKEELGRGSYAAVTVGIFRGLRVAVKSLHNIIISDFN-LALFSREMDIASRVRHPNLVQFIGA-TKVDNPLILTELMST-SLNQELHRNQLTNQ--QI
|      |||.|. |  |  ||  |||| | |  | | | |  | || .. .. |||| .||.|. .    ..| .| |.  || . ||   .  .   .
IKIGNRIGRGNYGEVFRGTWRGTQVAVKMLFNHNINDENFLNEFHREINLMCQLRHPNICQFMGTCNNPPDICICMEYMPRGSLYNILHDESIEMDWPLM

LSIAQDVALGLNYLHLFKPQAIIHRDISSPNVL
.... |.| |..|||   |  |||||  | | |
KQMMFDCAKGMIYLHCCNP-IIIHRDLKSHNLL
Kinase AqueK636.AA Dicty4-Unclassified 499-691 28 6.9e-21 68.23 In-house 1-201 (263) Show / Hide 
Range on Protein: 499-691
Range on HMM: 1-201/263
Sequence Identity: 28% (60 aa)

ILTKEELGRGSYAAVTVGIFRGLRVAVKSLHNIIISDFN---LALFSREMDIASRVRHPNLVQFIGATKVDNP-------LILTELM-STSLNQELH---
|    ..|.|  . |  |. .|  |||| . |     |    .  | .| .|   . |||||.  |.    ||        | .|.| .  |    |   
IQIDQFIGKGHFSKVHKGNWKGKDVAVKKF-NENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYCI--NPRSHKSTMCIVMEFMHKGNLFEVIHSKP

--RNQ---LTNQQILSIAQDVALGLNYLHLFKPQAIIHRDISSPNVLLKPCTGPAGYEAKVSDYGTAKVVQAENTGTVMPGNVAYAAPEAPIPDQHSPAM
  ..|   |    |. .| |.| |. .||      .||||| | |.|.        . .|. | | . |.    . |   | ..  .||         . 
SEQQQPIKLDDTLIIKYAFDIAQGMQHLHT---RNFIHRDIKSSNILMD-----KHFNIKIADFGISRVIDFNFNMTTIAGTPKWESPECLMHESYNQKS

DVYSYSVLLMEM
||||| ..| |.
DVYSYAMMLYEL
Kinase AqueK636.AA Pkinase_Tyr 499-691 24 9.8e-19 64.08 Pfam 1-207 (270) Show / Hide 
Range on Protein: 499-691
Range on HMM: 1-207/270
Sequence Identity: 24% (52 aa)

ILTKEELGRGSYAAVTVGIFR------GLRVAVKSLHNIIISDFN--LALFSREMDIASRV-RHPNLVQFIGATK-VDNP---LILTELMST-SLNQELH
|   ..||.|..  |  |. .      .. ||||.| .   .. .  .. | ||. | .   .|||.|...|.    . |   .| .|.|   .|   |.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

RN-----QLTNQQILSIAQDVALGLNYLHLFKPQAIIHRDISSPNVLLKPCTGPAGYEAKVSDYGTAKVVQAENTG-TVMP---GNVAYAAPEAPIPDQH
..     .|| ...|......| |..||.  .   .||||.   |.|..      .  .|..| | |. .. . .  ..       .   |||.      
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKN---CIHRDLAARNCLVTE-----NNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKF

SPAMDVYSYSVLLMEM
. . ||.|. ||. |.
TTKSDVWSFGVLMWEI
Kinase AqueK636.AA LRRK 499-668 21 1.4e-16 55.11 In-house 1-249 (351) Show / Hide 
Range on Protein: 499-668
Range on HMM: 1-249/351
Sequence Identity: 21% (55 aa)

ILTKEELGRGSYA-AVTVGIFRG----------------------------LRVAVKSLHNI------------------------------IISDF--N
.   |..|||...  |  ...||                              ||.|... .                              ...|.  .
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

LALFSREMDIASRVRHPNLVQFIGATKVDNPLIL-TELMST-SLNQELH---RNQ-------LTNQQILSIAQDVALGLNYLHLFKPQAIIHRDISSPNV
. .| .|. | |. .|||.|. .| .   .||.. .|...  .|.. ||   ...       .. . .| || ..| |..||| ..|  |||||  |||.
FREFRHEVWIMSHLNHPNIVSLKGFCI--HPLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNPP-IIHRDLKSPNI

LLKPCTGP-------AGYEAKVSDYGTAK---VVQAENTGTVMPGNVAYAAPE
||.  . .       | . ||..|.|.     ... . . ..  ||  . |||
LLWSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMGVAKGCV-GNPGWMAPE
Kinase AqueK636.AA TyrKc 499-741 20 3.4e-16 39.19 SMART 1-280 (280) Show / Hide 
Range on Protein: 499-741
Range on HMM: 1-280/280
Sequence Identity: 20% (59 aa)

ILTKEELGRGSYAAVTVGIFRGLRVAVKSLHNIIISDFNLALFSREMDIASRV--RHPNLVQFIGATKV--------DNPLILTELMST-SLNQELHRNQ
|  ...||.| .  |  |. . . ||||.|..       .. | ||. | ...  .|||.|...|.           . ..|..|.|.  .|.. |....
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR

--LTNQQILSIAQDVALGLNYLHLFKPQAIIHRDISSPNVLLKPCTGPAGYEAKVSDYGTAKVVQAE-------NTGTV-----MP--GNVAYAAPEAPI
  |.... ||.. ..| | .|||      .||||.   |.|..         .|.|| | .. .  .        . ..           .   |||.  
PKLCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENH-----TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECIN

PDQHSPAMDVYSYSVLLMEM-NLCSRPE---------MTTAKRDVQSG------SV--------SWSDMKSLIQRGLNANPRARPTMAQVRGVS
    ... ||.|. |.. |.  ..  |           . . ..|..|                  ..| .....  ...|  |||.....   
YGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase AqueK636.AA Pkinase 499-691 22 3.7e-16 58.22 Pfam 1-205 (293) Show / Hide 
Range on Protein: 499-691
Range on HMM: 1-205/293
Sequence Identity: 22% (48 aa)

ILTKEELGRGSYAAVTVGIFRGLR--VAVKSLHNIIISDFNLALFSR--EMDIASRVRHPNLVQFIGATK-VDNPLILTELMST-----SLNQELH---R
. ... .|.||.. |  .. .| .  |||| .    ...  .    |  |  |  |..||| |.....    |.. . .|..       .|   ..   .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

NQL--TNQQILSIAQDVALGLNYLHLFKPQAIIHRDISSPNVLLK-PCTGPAGYEAKVSDYGTAKVVQAENTGTVMPGNVA---YAAPEAPI-PDQHSPA
. .  . ... ...  .. ||.|.|      |||||. . |.|..  .. .|    |..| | ||... .  .. | . .    |.|||       ..|.
GCFYFSEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDA--CVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPK

MDVYSYSVLLMEM
 |..|. ..| ||
VDMWSCGCILYEM
Kinase AqueK636.AA MLK 716-741 26 0.000618 9.69 In-house 266-291 (291) Show / Hide 
Range on Protein: 716-741
Range on HMM: 266-291/291
Sequence Identity: 26% (7 aa)

MKSLIQRGLNANPRARPTMAQVRGVS
.|.|...  |..|. ||...|.    
WKKLMKQCWNQDPHKRPSFRQIVQHL
Kinase AqueK636.AA Dicty4 717-737 33 0.012575 4.78 In-house 249-269 (277) Show / Hide 
Range on Protein: 717-737
Range on HMM: 249-269/277
Sequence Identity: 33% (7 aa)

KSLIQRGLNANPRARPTMAQV
|.|||. .. .|  ||.....
KHLIQWCWDHDPQHRPSFEEI
Kinase AqueK636.AA DRK 719-737 31 0.126165 1.32 In-house 234-252 (258) Show / Hide 
Range on Protein: 719-737
Range on HMM: 234-252/258
Sequence Identity: 31% (6 aa)

LIQRGLNANPRARPTMAQV
|... .| .|  ||.| ..
LMNDCWNEDPQHRPSMQEC
Kinase AqueK636.AA LRRK 706-737 25 0.128936 1.47 In-house 314-345 (351) Show / Hide 
Range on Protein: 706-737
Range on HMM: 314-345/351
Sequence Identity: 25% (8 aa)

VQSGSVSWSDMKSLIQRGLNANPRARPTMAQV
.. . . | ....|||   ...|. ||.. |.
YCPPCQPWHMYQDLIQHCWQHDPKKRPHFSQI
Kinase AqueK636.AA TKL 1128-1364 19 3.9e-48 166.25 In-house 1-364 (364) Show / Hide 
Range on Protein: 1128-1364
Range on HMM: 1-364/364
Sequence Identity: 19% (73 aa)

LGRGSYAAVTVGIFRG----------LRVAVKSLHTIIISDYNL-------------------------ALFSREMNIASRIRHPNLVQFIGATK-----
.|.|... |  |..||            |||| ...   .  ..                           . .|... ||.||||.|||.|. .     
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

---------VGNPLVLTELM-STSLNQELHKNQITNQQILNIAQDVALGLNYLHLFKP-----QPIIHRDVSSPNVLLKPCSGP---------AGYEAKV
          |..   .|..   ||   ||      .|....|.|.|.|.||||  .|      ||||||  |.|.|..    .         | . .|.
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-----WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKI

ADYGTAKVMQAEN--------------------TGTIMPGNAAYAAPEAPIPD----------------QHSPAMDVYSYSILLMEMNLCSLPEMTTAER
.|.|....|. ..                    |     |. .. |||.   .                . |...||||. |.| |.  . .|.    ..
CDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPYM

EVQ---------AGSV-----------------------SWSDMKSLIQRGLYVNPKARPTMAQVIESL
...         .. .                        . .||.|.|.    .|..||.. .... |
PMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase AqueK636.AA MLK 1122-1314 26 1.3e-35 121.02 In-house 1-229 (291) Show / Hide 
Range on Protein: 1122-1314
Range on HMM: 1-229/291
Sequence Identity: 26% (60 aa)

TLTKEELGRGSYAAVTVGIFRGLR-----VAVKSLHTIIISDYNLA-----LFSREMNIASRIRHPN----LVQFIGA-TKVGN-PLVLTELMST-SLNQ
 ...| .| ||. .|  | .|. .     ||||  .. |. |   .      | .| .......|||     .|| |. .. ..  ....| ..  ||. 
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYN

ELHKNQ---------------ITNQQILNIAQDVALGLNYLHLFKPQPIIHRDVSSPNVLLKP-CSGPAGYEAKVADYGTAKVMQAE-NTGTIMPGNAAY
 || ..               .. ....|.| ..| |..|||  .|.||||||  |.|.|.   |.  ..  .|..| ||.. ..    . . ..|..|.
VLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMMSNAGTYAW

AAPEAP---IPDQHSPAMDVYSYSILLMEM
 |||.      .. | . ||.|. ..| ||
MAPEVIQQFRCEKYSEKCDVWSWGVVLWEM
Kinase AqueK636.AA TKL-Unique 1124-1314 29 2.8e-31 107.64 In-house 1-221 (290) Show / Hide 
Range on Protein: 1124-1314
Range on HMM: 1-221/290
Sequence Identity: 29% (66 aa)

TKEELGRGSYAAVTVGIFRGLRVAVKSLHTIIISDYNLA---LFSREMNIASRIR-HPNLVQFIGATK---VGNP--LVLTELMST-SLNQELH------
  . .|.|.|..|  |..||  ||.|..|    .| ..     |..| |. .... |||.|...|...   | .|     .| ..  ||.  ||      
FWNKIGEGGYGQVYKGKWRGYPVAIKQFHP--NEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNN

-----KNQITNQQILNIAQDVALGLNYLHLFKPQPIIHRDVSSPNVLLKPCSGPAGYEAKVADYGTAKVMQAENTGTIM----------PGNAAYAAPEA
     .. ...||....|.|.|.|..|||  .|  |||||  |.|.|.   |  | . .|..| |..|.   .|..|.            |.. ..||| 
NNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEV

PIP--DQHSPAMDVYSYSILLMEM
     .| |   ||||..| | |.
LRMNFCQYSEKSDVYSFGIVLWEI
Kinase AqueK636.AA Dicty4 1124-1314 31 1.8e-27 88.79 In-house 3-210 (277) Show / Hide 
Range on Protein: 1124-1314
Range on HMM: 3-210/277
Sequence Identity: 31% (67 aa)

TKEELGRGSYAAVTVGIFRGLRVAVKSL--HTIIISDYNLALFSREMNIASRIRHPNLVQFIGA-T----KVGNPLVLTELM-STSLNQELHK------N
. ...|.||.. |  |. ||  |||| |  | .  . . |  | .| .| . |||||...| || |    . | ..  ||.| ...|   ||.       
IEQRIGKGSFGEVYKGTWRGKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSEQQQ

QITNQ--QILN---IAQDVALGLNYLHLFKPQPIIHRDVSSPNVLLKPCSGPAGYEAKVADYGTAKVMQAENTGTI----MPGNAAYAAPEAPIPDQHSP
 |. .   |.    .| |.|.|.|.||   |  |||||  | | |       . . .||.| | ...|. . . .     . | ... |||    .    
SIKLDWPLIKRAMRMAFDAARGMNWLHCCNPV-IIHRDLKSHNLLVD-----KNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPYNE

AMDVYSYSILLMEM
. ||||..|.| |.
KADVYSFGIVLWEI
Kinase AqueK636.AA CZAK 1123-1314 29 1.9e-25 89.48 In-house 1-215 (279) Show / Hide 
Range on Protein: 1123-1314
Range on HMM: 1-215/279
Sequence Identity: 29% (63 aa)

LTKE-ELGRGSYAAVTVGIFRGLRVAVKSLHTIIISDYNL----ALFSREMNIASRIRHPNLVQFIGATKVGN---PLVLTELMS-TSLNQELHKNQITN
|. . . |.| .  |  .  ||  ||.| .| .   .         | .|  | |  .||| |||.||   ..     . .| |   || . |       
LKFGQTIGQGFFGEVYKAYWRGKDVAIKIIHRNQFRNKDENKEENMFQKEVSIMSKLCHPNCVQFLGACSEDGPNHHCIVMEWMGGGSLRRLLTDHYFYH

QQ----ILNIAQDVALGLNYLHL-FKPQPIIHRDVSSPNVLLKPCSG--------PAGYEAKVADYGTAKVMQAENTG-TIMPGNAAYAAPEAPIPDQHS
.|     .|.| |.| | ||||  .|| ||.||| || |.||                  .|..|.|  . |    .  |   |  .. |||  . .  .
KQNPHLQWNMAIDIARGMNYLHDNWKPNPILHRDLSSRNILLDHSYTPKNPVVSSRQDIICKINDFGLSREMMEQPFEMTQTMGCLCWMAPECFKGENYT

PAMDVYSYSILLMEM
.  ||||. ..| ..
EKVDVYSFGMILWCI
Kinase AqueK636.AA TK 1122-1314 13 7.6e-25 79.57 In-house 1-387 (486) Show / Hide 
Range on Protein: 1122-1314
Range on HMM: 1-387/486
Sequence Identity: 13% (54 aa)

TLTKEELGRGSYA---AVTVGIFRGL---------------------------RVAVKSLHTIIISDYNLAL---------------FSREMNIAS--RI
    ..||.| .     |  |. ||.                           .|||| |.    .. .  .               . .|| . .    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

RHPNLVQFIG-ATKVGN------------PLVLTELMS-TS----LNQELHKN-----------------------------------------------
.|||.|...|  |....            .....|.|.  .    | . |.|.                                               
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

------------------------------QITNQQILNIAQDVALGLNYLHLFKP---QPIIHRDVSSPNVLLKPCSG------PAGYEAKVADYG---
                              |.| .| | .....| |. |||  .    | ..|||.   |.|.             |. .|.||.|   
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----TAKVMQAENTGTIMPGNAA---------------------------YAAPEAPI---------PDQHSPAMDVYSYSILLMEM
      |. .. .   . . .  .                           . |||.              .... ||.|. .|. |.
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEI
Kinase AqueK636.AA S_TKc 1122-1365 18 2e-24 88.37 SMART 1-231 (231) Show / Hide 
Range on Protein: 1122-1365
Range on HMM: 1-231/231
Sequence Identity: 18% (50 aa)

TLTKEELGRGSYAAVTVGIFRG--LRVAVKSLHTIIISDYNLALFSREMNIASRIRHPNLVQFIGATKVGNPLVLTELMST---SLNQELHKNQ------
    ...|.|... |  .. ..   .||.| ..           . ||..| .. .|||.|.....   ..  . .|....   .| . ..|..      
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-ITNQQILNIAQDVALGLNYLHLFKPQPIIHRDVSSPNVLLKPCSGPAGYEAKVADYGTAKVMQAENTGTIMPGNAAYAAPEAPIPDQHSP-AMDVYSYS
 ..  ..  ... ....|.|.|  .   |||||.   |.||         . |..| | |...      | . |   | |||     .... . |..|  
PFPE-HARFYMYQICCALEYCHSHG---IIHRDLKPENILLDE-------HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCG

ILLMEMNLCSLPEMTTAEREVQAGSVSWSDMKSLIQRGLYVNPKARPTMAQVIE--------SLK
..| ||     |   . ..  .      ...|..|.. | ..|. |||  .. .           
CILYEMLCGYPPFP-QMQMMFKKIG--SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK636.AA STE 1123-1314 16 6.4e-21 70.68 In-house 1-261 (359) Show / Hide 
Range on Protein: 1123-1314
Range on HMM: 1-261/359
Sequence Identity: 16% (45 aa)

LTK-EELGRGSYAAVTVGIFR-----------------GLRVAVKSLH---------------TIIISDYNLALFSREMNIASRIR--HPNLVQFIGATK
... |..|.|..  |  .. .                 | ..|.| ..               . .. . ..  . .|..| .. .  ||| |...|.  
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

VG--------NPLVLTELMS-TSLNQELHKNQIT---------------NQQILNIAQDVALG-LNYLHLFKPQPIIHRDVSSPNVLLKPCSGPAGYEAK
..        .  .  |.|.  || . .... ..                .||  |....  | |.|||  .   |||||. . |.||          .|
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH---IIHRDIKPANILL----------VK

VADYGTAKVMQAENTGT-----------------IMPGNAAYAAPEAPIP------DQHSPAMDVYSYSILLMEM
 .| |... .. ....                   . |   . |||   .      ....   |..|  ....||
LCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEM
Kinase AqueK636.AA Dicty4-Unclassified 1125-1314 27 2e-19 63.18 In-house 4-201 (263) Show / Hide 
Range on Protein: 1125-1314
Range on HMM: 4-201/263
Sequence Identity: 27% (57 aa)

KEELGRGSYAAVTVGIFRGLRVAVKSLHTIIISDY--NLALFSREMNIASRIRHPNLVQFIGATKVGNP-------LVLTELM-STSLNQELH-----KN
  ..|.|  . |  |. .|  |||| .     .     .  | .|  |   | |||||.  |.    ||        . .|.| .  |    |     ..
DQFIGKGHFSKVHKGNWKGKDVAVKKFNENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYCI--NPRSHKSTMCIVMEFMHKGNLFEVIHSKPSEQQ

Q-ITNQQ--ILNIAQDVALGLNYLHLFKPQPIIHRDVSSPNVLLKPCSGPAGYEAKVADYGTAKVMQAENTGTIMPGNAAYAAPEAPIPDQHSPAMDVYS
| |      |. .| |.| |. .||      .||||. | |.|.        . .|.|| | . |     . |   |  .  .||         . ||||
QPIKLDDTLIIKYAFDIAQGMQHLHTRN---FIHRDIKSSNILMD-----KHFNIKIADFGISRVIDFNFNMTTIAGTPKWESPECLMHESYNQKSDVYS

YSILLMEM
| ..| |.
YAMMLYEL
Kinase AqueK636.AA DRK 1129-1314 35 2e-19 62.49 In-house 8-195 (258) Show / Hide 
Range on Protein: 1129-1314
Range on HMM: 8-195/258
Sequence Identity: 35% (69 aa)

GRGSYAAVTVGIFRGLRVAVKSLHTIIISDYN-LALFSREMNIASRIRHPNLVQFIGA-TKVGNPLVLTELMST-SLNQELHKNQITNQ--QILNIAQDV
|||.|. |  |  ||  |||| |    | | | |  | || |. .. |||| .||.|. .    ... .| |.  || . ||   |  .   .. .. |.
GRGNYGEVFRGTWRGTQVAVKMLFNHNINDENFLNEFHREINLMCQLRHPNICQFMGTCNNPPDICICMEYMPRGSLYNILHDESIEMDWPLMKQMMFDC

ALGLNYLHLFKPQPIIHRDVSSPNVLLKPCSGPAGYEAKVADYGTAK----VMQAENTGTIMPGNAAYAAPEAPIPDQHSPAMDVYSYSILLMEM
| |..|||   |  |||||  | | |         .  ||||.| .     . |   . | | |     |||    .      ||||. | | |.
AKGMIYLHCCNPI-IIHRDLKSHNLLVD-----EHWQVKVADFGLSTRFKKHKQHKFAMT-MCGTPCWTAPEVLRNQRYTEKADVYSFAIVLWEC
Kinase AqueK636.AA LRRK 1122-1268 22 2.8e-18 61.28 In-house 1-224 (351) Show / Hide 
Range on Protein: 1122-1268
Range on HMM: 1-224/351
Sequence Identity: 22% (52 aa)

TLTKEELGRGSYA-AVTVGIFRG----------------------------LRVAVKSLHT--------------------------------IIISDYN
    |..|||...  |  ...||                              ||.|....                                .. .  .
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

LALFSREMNIASRIRHPNLVQFIGATKVGNPLVL-TELMST-SLNQELHKNQ----------ITNQQILNIAQDVALGLNYLHLFKPQPIIHRDVSSPNV
. .| .|. | |. .|||.|. .| .   .|| . .|...  .|.. ||...          |. . .| || ..| |..||| ..| ||||||  |||.
FREFRHEVWIMSHLNHPNIVSLKGFCI--HPLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNP-PIIHRDLKSPNI

LLKPCSGP-------AGYEAKVADYGT
||.  . .       | . ||.||.|.
LLWSSPQNHSPNYPNAHVCAKIADFGI
Pkinase_Tyr AqueK636.AA Pkinase_Tyr 1121-1267 25 5.3e-17 58.2 Pfam 1-156 (270) Show / Hide 
Range on Protein: 1121-1267
Range on HMM: 1-156/270
Sequence Identity: 25% (42 aa)

VTLTKEELGRGSYAAVTVGIFR------GLRVAVKSLHTIIISDYN--LALFSREMNIASRI-RHPNLVQFIGATK-VGNP---LVLTELMST-SLNQEL
.|.  ..||.|..  |  |. .      .. ||||.|     .. .  .. | ||..| . . .|||.|...|.    | |   .. .|.|   .|   |
ITFG-KKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

HKN-----QITNQQILNIAQDVALGLNYLHLFKPQPIIHRDVSSPNVLLKPCSGPAGYEAKVADYG
.|.     ..| ...|......| |..||.  .   .||||.   |.|..      .  .|..| |
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKN---CIHRDLAARNCLVTE-----NNVVKICDFG
Kinase AqueK636.AA TyrKc 1122-1364 19 1e-15 31.29 SMART 1-280 (280) Show / Hide 
Range on Protein: 1122-1364
Range on HMM: 1-280/280
Sequence Identity: 19% (57 aa)

TLTKEELGRGSYAAVTVGIFRGLRVAVKSLHTIIISDYNLALFSREMNIASRI--RHPNLVQFIGATKV--------GNPLVLTELMST-SLNQELHKNQ
   ...||.| .  |  |. . . ||||.|.        .. | ||..| ...  .|||.|...|.           . .....|.|.  .|.. |.|..
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR

--ITNQQILNIAQDVALGLNYLHLFKPQPIIHRDVSSPNVLLKPCSGPAGYEAKVADYGTAKVMQAE-------NTGTI-----MP--GNAAYAAPEAPI
  ..... |... ..| | .|||     ..||||    |.|..     ... .|..| | ..    .        . .                |||.  
PKLCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVG-----ENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECIN

PDQHSPAMDVYSYSILLMEM-NLCSLPE-------MTTAE--REVQAG------SV--------SWSDMKSLIQRGLYVNPKARPTMAQVIESL
    ... ||.|. ... |.  ..  |        |. .|  . |..|                  ..| .....    .|. |||.....| .
YGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase AqueK636.AA Pkinase 1122-1314 21 7.7e-13 46.49 Pfam 1-205 (293) Show / Hide 
Range on Protein: 1122-1314
Range on HMM: 1-205/293
Sequence Identity: 21% (46 aa)

TLTKEELGRGSYAAVTVGIFRGLR--VAVKSLHTIIISDYNLALFSR--EMNIASRIRHPNLVQFIGATK-VGNPLVLTELMST-----SLNQELH---K
  ... .|.||.. |  .. .| .  |||| .    ...  .    |  |  |  |..||| |.....    ... . .|..       .|   ..   .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

NQI--TNQQILNIAQDVALGLNYLHLFKPQPIIHRDVSSPNVLLK----PCSGPAGYEAKVADYGTAKVMQAENTGTIMPGNAA---YAAPEAPI-PDQH
. .  . ... ...  .. ||.|.|      |||||. . |.|..    ...       |..| | ||... .  .. | . .    |.|||       .
GCFYFSEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDA-----CVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEVIRGGQYY

SPAMDVYSYSILLMEM
.|. |..|. ..| ||
GPKVDMWSCGCILYEM
Kinase AqueK636.AA MLK 1339-1364 26 7.8e-05 12.85 In-house 266-291 (291) Show / Hide 
Range on Protein: 1339-1364
Range on HMM: 266-291/291
Sequence Identity: 26% (7 aa)

MKSLIQRGLYVNPKARPTMAQVIESL
.|.|...    .|. ||...|... |
WKKLMKQCWNQDPHKRPSFRQIVQHL
Kinase AqueK636.AA Dicty4-Unclassified 1339-1364 42 0.000257 10.65 In-house 238-263 (263) Show / Hide 
Range on Protein: 1339-1364
Range on HMM: 238-263/263
Sequence Identity: 42% (11 aa)

MKSLIQRGLYVNPKARPTMAQVIESL
.|.||   .   |. |||| |.|. |
WKKLIKWCWHNDPNKRPTMNQIIQYL
Kinase AqueK636.AA Dicty4 1340-1366 31 0.000927 8.61 In-house 249-277 (277) Show / Hide 
Range on Protein: 1340-1366
Range on HMM: 249-277/277
Sequence Identity: 31% (9 aa)

KSLIQRGLYVNPKARPTMAQVIES--LKG
|.|||. .  .|. ||.....|.   |  
KHLIQWCWDHDPQHRPSFEEIIQRRILEH
Kinase AqueK636.AA LRRK 1329-1366 26 0.002572 7.57 In-house 314-351 (351) Show / Hide 
Range on Protein: 1329-1366
Range on HMM: 314-351/351
Sequence Identity: 26% (10 aa)

VQAGSVSWSDMKSLIQRGLYVNPKARPTMAQVIESLKG
.. . . | ....|||     .|| ||.. |... |. 
YCPPCQPWHMYQDLIQHCWQHDPKKRPHFSQIVKRLSQ
Kinase AqueK636.AA TK 1350-1364 46 0.003704 5.58 In-house 472-486 (486) Show / Hide 
Range on Protein: 1350-1364
Range on HMM: 472-486/486
Sequence Identity: 46% (7 aa)

NPKARPTMAQVIESL
.|. |||..|. | |
DPEDRPTFSQLHEQL
Kinase AqueK636.AA TKL-Unique 1342-1364 34 0.004076 7.05 In-house 268-290 (290) Show / Hide 
Range on Protein: 1342-1364
Range on HMM: 268-290/290
Sequence Identity: 34% (8 aa)

LIQRGLYVNPKARPTMAQVIESL
|||..   .|  ||.  ..|..|
LIQQCWHHDPSQRPSFDEIIHRL
Kinase AqueK636.AA DRK 1342-1366 28 0.004365 6.34 In-house 234-258 (258) Show / Hide 
Range on Protein: 1342-1366
Range on HMM: 234-258/258
Sequence Identity: 28% (7 aa)

LIQRGLYVNPKARPTMAQVIESLKG
|... .  .|  ||.| ...| |  
LMNDCWNEDPQHRPSMQECLERLEA
Kinase AqueK636.AA Pkinase 1333-1364 22 0.066611 7.81 Pfam 244-293 (293) Show / Hide 
Range on Protein: 1333-1364
Range on HMM: 244-293/293
Sequence Identity: 22% (11 aa)

SVSW----------------SDMKSLIQRGLYVNPKARPTMAQVIES--L
|.|.                ...|..| . | ..|| ||| .|. ..  .
SISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase AqueK636.AA Pkinase_Tyr 1350-1364 40 0.16658 5.72 Pfam 256-270 (270) Show / Hide 
Range on Protein: 1350-1364
Range on HMM: 256-270/270
Sequence Identity: 40% (6 aa)

NPKARPTMAQVIESL
.|. |||.....| |
DPEDRPTFSEIHEQL