AqueK655

Species: A.queenslandica
Alias: AqueK655
External Links:
Annotation:

Classification

Group: TKL
Family: MLK
Subfamily: LZK

Sequence

Name Sequence Type Origin Length Description Download
AqueK655.AA Protein None 515 None Fasta, JSON
AqueK655.kin_dom Protein Kinase Domain None 241 None Fasta, JSON

Protein domain

Protein domains of AqueK655.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase AqueK655.AA LZK 106-346 54 2.3e-132 446.04 In-house 1-241 (241) Show / Hide
Range on Protein: 106-346
Range on HMM: 1-241/241
Sequence Identity: 54% (133 aa)

IRELSYIGKGGQGAVFSGKYRDNEVAVKKVNDPKQTELKILRKLSHPNIVKCLGVCNKPPCYCIVMEYCRLGNLFDYIRKTSTKIMPFDVIQWSREICTG
|.||  .| | |||||.|..|  .||||||.| | |. | |||| ||||.. .||| . |||||.||||  | | . . .   .| |   ..||..|  |
ISELQWLGSGAQGAVFRGWFRNETVAVKKVRDLKETDIKHLRKLKHPNIIEFKGVCTQSPCYCIIMEYCPHGQLYE-VLRERRTITPQLMVDWSKQIAQG

MQFLHSKKLIHRDLKSLNVLVSDNHSMKITDFGVSRTLDHQ-FTKMTVIGSVAWMAPELIRSEPCSEKVDIWSFGVCLWELLTREEPYKDLNHGAVIYGV
|..||. | ||||||| |.|.| | ..|| ||| |. .     |||   | |||||||.|| |||||||||||||| |||.||.| ||||    |.|.||
MHYLHQHKIIHRDLKSPNILISHNDVVKICDFGTSHMWNEMDSTKMSFCGTVAWMAPEVIRNEPCSEKVDIWSFGVVLWEMLTCEIPYKDVDSMAIIWGV

GSTTLSLPIPTGCPSDLKSLLQKCWQQKPKSRPSFSQIIEEL
||  |.||.|  ||  .| |.. ||.|||  ||||.||   .
GSNSLHLPMPSTCPEGFKLLMKQCWSQKPRNRPSFRQILMHW

Kinase AqueK655.AA MLK 106-346 38 5.6e-117 394.92 In-house 1-291 (291) Show / Hide
Range on Protein: 106-346
Range on HMM: 1-291/291
Sequence Identity: 38% (111 aa)

IRELSYIGKGGQGAVFSGKYRDNE-----VAVKKVN-------------DPKQTELKILRKLSHPN----IVKCLGVCNKPPC-YCIVMEYCRLGNLFDY
|... .||.|..|.|..|..| ..     ||||.|.             . ...| ..||.|||||    |.. .|||..||| .|||||||. | |...
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNV

IRKTSTKIM-------------PFDVIQWSREICTGMQFLHSKK---LIHRDLKSLNVLVSD------NHSMKITDFGVSRTLDHQ-FTKMTVIGSVAWM
..  ..|.|             .  ...|.  .  ||..|||..   .||||||| |.|...      .  .||.|||.|| . .   ..|  .|..|||
LHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMMSNAGTYAWM

APELI---RSEPCSEKVDIWSFGVCLWELLTREEPYK-DLNHGAVIYGVGSTTLSLPIPTGCPSDLKSLLQKCWQQKPKSRPSFSQIIEEL
||| |   |.|..|||.|.||.||.|||.||||.||| ...  |....|. . | .||| .||  .|.|...||.|.|..||||.||...|
APEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVPYKQHYDPMAIAWWVAYNGLRPPIPSTCPEHWKKLMKQCWNQDPHKRPSFRQIVQHL

Kinase AqueK655.AA TKL 112-346 28 2.3e-102 346.36 In-house 1-364 (364) Show / Hide
Range on Protein: 112-346
Range on HMM: 1-364/364
Sequence Identity: 28% (107 aa)

IGKGGQGAVFSGKYRD----------NEVAVKKVN----------------------------------DPKQTELKILRKLSHPNIVKCLGVCNKPPC-
||.|| | |. ||.|           ..||||| .                                  . .  |......|.|||||...|.|. ||| 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------YCIVMEYCRLGNLFDYIRKTSTKIMPFDVIQWSREICTGMQFLHS--------KKLIHRDLKSLNVLVSDNHS--------------M
            .|||||||  |.|..|.        .   ..|...|. ||..|||        ...||||||| |.|| .|                 
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCC

KITDFGVSRTLDHQF--------------------TKMTVIGSVAWMAPELIRSE----------------PCSEKVDIWSFGVCLWELLTREEPYKDLN
||.||| ||.... .                    |.||..|. .|||||..| .                . |||.|..|||..|||.|||..||.|..
KICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYP

HGAVI---------YGVGSTTLSLPIP------------TGCPSDLKSLLQKCWQQKPKSRPSFSQIIEEL
.  .|         ..|..  | .|||            . || ..|.|.|.||...|..||||..|...|
YMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL

Kinase AqueK655.AA Dicty4 106-348 37 4e-80 266.91 In-house 1-277 (277) Show / Hide
Range on Protein: 106-348
Range on HMM: 1-277/277
Sequence Identity: 37% (103 aa)

IRELSYIGKGGQGAVFSGKYRDNEVAVKKVNDPKQT-----------ELKILRKLSHPNIVKCLGVCN----KPPCYCIVMEYCRLGNLFDYIRK-----
|   . ||||. | |. |. |  |||||| |  .|.           | .|. |..||||....| |.    .|.  |||.||.  |||.  ...     
INIEQRIGKGSFGEVYKGTWRGKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSEQ

-TSTKIMPFDVIQ---WSREICTGMQFLHS--KKLIHRDLKSLNVLVSDNHSMKITDFGVSR----TLDHQFTKMTVIGSVAWMAPELIRSEPCSEKVDI
  |.|.   ....     . .  ||. ||.     ||||||| | ||..|   |..||| |.      ||..  ||..|...|||||  ...|  ||.| 
QQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPYNEKADV

WSFGVCLWELLTREEPYK--DLNHGAVIYGVGSTTLSLPIPTGCPSDLKSLLQKCWQQKPKSRPSFSQIIEE--LNV
 |||  |||.|||.|||     .   .. .|..  | .|||  ||  .|.|.|.||   |..||||..||..  |. 
YSFGIVLWEILTRQEPYQKHHMPYMQFVRAVCNKKLRPPIPDWCPPSWKHLIQWCWDHDPQHRPSFEEIIQRRILEH

Kinase AqueK655.AA TKL-Unique 109-346 34 1.1e-77 264.44 In-house 2-290 (290) Show / Hide
Range on Protein: 109-346
Range on HMM: 2-290/290
Sequence Identity: 34% (99 aa)

LSYIGKGGQGAVFSGKYRDNEVAVKKVN---DPKQT-------ELKILRKLS-HPNIVKCLGVCN----KPPCYCIVMEYCRLGNLFDYIR---------
.. || ||.|.|. ||.|  .||.|. .   |.  .       |.... ||  |||||.. |.|     .|| .||||||| .|.| |..          
WNKIGEGGYGQVYKGKWRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNNN

KTSTKIMPFDVIQWSREICTGMQFLHSKK--LIHRDLKSLNVLVSDN-----HSMKITDFGVSRTLDHQ---FTKM-------TVIGSVAWMAPELIRS-
. ..|. .  ...  . |  || .||...   |||||||.|.||. |      . || ||| |....     ....       |..||  |||||..|. 
NNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLRMN

-EPCSEKVDIWSFGVCLWELLTREE------PYKDLNHGAVIYGVGS--TTLSLPIPTGCPSDLKSLLQKCWQQKPKSRPSFSQIIEEL
 .  |||.|..|||..|||..||.       ||..... ...  | .    . .|||. || ... |.|.|| . |  ||||..||..|
FCQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGMDQEQWCEMVHYMEENYRPPIPNHCPKEYRDLIQQCWHHDPSQRPSFDEIIHRL

Kinase AqueK655.AA ZAK 106-345 40 2.2e-75 256.78 In-house 1-257 (257) Show / Hide
Range on Protein: 106-345
Range on HMM: 1-257/257
Sequence Identity: 40% (105 aa)

IRELSYIGKGGQGAVFSGKY--RD---NEVAVKKVNDPKQTELKILRKLSHPNIVKCLGVCNKPPC-YCIVMEYCRLGNLFDYIRKTSTKIMP-------
|     .| |  |.|....    |    |.|||||      |  || |..| ||.   |.|  ||  | || ||  .| |.|||     . |        
IQFFDHCGVGTFGSVYRANWISQDGSQREIAVKKVFKIEK-EAEILSKIRHRNIIQFYGICKEPPNDYFIVTEYAEKGSLYDYIHSNRSQEMDSSSGGNS

FDVI-QWSREICTGMQFLH---SKKLIHRDLKSLNVLVSDNHSMKITDFGVSRTLDHQFTKMTVIGSVAWMAPELI-RSEPCSEKVDIWSFGVCLWELLT
.|.| .|  .|  ||..||     | ||||||| || .  |  .|| ||| || . |  | |   |  .|||||.|  ||| .|  |.||.|| |||.||
MDHIMKWATQIAKGMHYLHMDAPDKIIHRDLKSRNVVIDKNGVCKICDFGTSRDFHHHCTHMSWVGTFPWMAPEMILQSEPVTETCDVWSYGVVLWEMLT

REEPYKDLNHGAVIYGVGSTTLSLPIPTGCPSDLKSLLQKCWQQKPKSRPSFSQIIEE
|| ||||.    .   .      | ||  ||  .| |. .||.  || ||.. ||. .
REVPYKDYEEFQIFWMIVQKNIRLTIPPSCPRPFKQLMHQCWKMDPKDRPNMRQIQSI

Kinase AqueK655.AA Pkinase 106-346 25 4.6e-75 260.47 Pfam 1-293 (293) Show / Hide
Range on Protein: 106-346
Range on HMM: 1-293/293
Sequence Identity: 25% (76 aa)

IRELSYIGKGGQGAVFSGKYRDNE--VAVKKVN----DPKQT-------ELKILRKLSHPNIVKCLGVCNKPPCYCIVMEYCRLG----NLFDYIR-KTS
.. .. ||.|. | |. .. ....  ||||...    ....        |..|...|.|||||......  .. ...|||||. |     |||||. . .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

TKI--MPFDVIQWSREICTGMQFLHSKKLIHRDLKSLNVLVSDNHSM----KITDFGVSRT--LDHQFTKMTVIGSVAWMAPELIR-SEPCSEKVDIWSF
...   . ... . ..|. |....||.. ||||||. |.|...|       ||.|||...   . ..   .|. |.  .||||.|| ... . |||.||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GVCLWELLTREEPYKDL------NHGAVIYGVGSTTLSLPIPTGCP-------------------SDLKSLLQKCWQQKPKSRPSFSQIIEE--L
|. |.|.|... |...       .. ..|. .... |. ..|. |.                   ...|... .|....||.||.. || .   .
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF

Kinase AqueK655.AA Pkinase_Tyr 106-346 33 2.6e-73 248.92 Pfam 1-270 (270) Show / Hide
Range on Protein: 106-346
Range on HMM: 1-270/270
Sequence Identity: 33% (91 aa)

IRELSYIGKGGQGAVFSGKYR------DNEVAVKKV--NDPKQ--------TELKILRKL-SHPNIVKCLGVCN--KPP-CYCIVMEYCRLGNLFDYIRK
|. .  .|.|  | |. |...      . .||||..  .  ..         |.||...| .|||||...|||   . |  ..|||||. .|.| || ||
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

T---STKIMPFDVIQWSREICTGMQFLHSKKLIHRDLKSLNVLVSDNHSMKITDFGVSRTL----DH-QFTKMTVIGSVAWMAPELIRSEPCSEKVDIWS
      .. . | .|....|. ||..|.||..|||||   |.||..|. .||.||| .|..       . .. .    . ||||| |.   ...| |.||
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGK-LPIKWMAPECINYGKFTTKSDVWS

FGVCLWELLTRE-EP-YKDLNHGAVIYGVGSTTLSLPIPTGCPSDLKSLLQKCWQQKPKSRPSFSQIIEEL
|||..||..|.  .| |...    |.  ..     .|.| .|| .. .|...||...|. ||.||.|.|.|
FGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL

Kinase AqueK655.AA TyrKc 106-346 31 1.4e-71 245.05 SMART 1-280 (280) Show / Hide
Range on Protein: 106-346
Range on HMM: 1-280/280
Sequence Identity: 31% (89 aa)

IRELSYIGKGGQGAVFSGKYRDNEVAVKKVNDPK----QTELKILRKL--SHPNIVKCLGVCNKP-------PCYCIVMEYCRLGNLFDYIRKTSTKIMP
|. .  .| |  | |. |...  .||||.... .      |..|..||  .|||||...||| ..       . ..|||||. .|.| ||.||.  |. .
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKLCM

FDVIQWSREICTGMQFLHSKKLIHRDLKSLNVLVSDNHSMKITDFGVSRTLDHQ--------FTKM----TVI--GSVAWMAPELIRSEPCSEKVDIWSF
 | ....  |. ||..||||..|||||   |.||..|| .||.||| || ...           ..           . ||||| |.   ...| |.|||
KDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDVWSF

GVCLWELLTREEPYKDL-----NHGAVIYGVGSTTLSLPIPTG--------CPSDLKSLLQKCWQQKPKSRPSFSQIIEEL
|||.||..|. ..            . ..    .   .|.|          ||... .. ..||. .|..||.||.|.|..
GVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF

Kinase AqueK655.AA S_TKc 106-349 29 6.1e-71 242.91 SMART 1-231 (231) Show / Hide
Range on Protein: 106-349
Range on HMM: 1-231/231
Sequence Identity: 29% (76 aa)

IRELSYIGKGGQGAVFSGKYRD--NEVAVKKVNDPKQTELKILRKLSHPNIVKCLGVCNKPPCYCIVMEYCRL--GNLFDYIRKTSTK-----IMPFDVI
 . |  ||||. | |. .. ..   .||.|....  . |..||.|  ||||||...|.    ....|||||    |.|||||.|  ..     . . .. 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIKEHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HAR

QWSREICTGMQFLHSKKLIHRDLKSLNVLVSDNHSMKITDFGVSRTLDHQFTKMTVIGSVAWMAPELIRSEPCSE-KVDIWSFGVCLWELLTREEPYKDL
 . ..|| .....||.. ||||||  |.|...    ||.|||..| |      .|..|.  .||||..   . .  |.|.||.|..|.|.|... |.   
FYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP--

NHGAVIYGVGSTTLSLPIPTGCPSDLKSLLQKCWQQKPKSRPSFSQIIE-E-----LNVI
.. ...  .|            ....|....||.|  |. ||.  .. . |        .
QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase AqueK655.AA TK 106-346 18 8.1e-64 212.53 In-house 1-486 (486) Show / Hide
Range on Protein: 106-346
Range on HMM: 1-486/486
Sequence Identity: 18% (90 aa)

IRELSYIGKGGQG---AVFSGKYRDN---------------------------EVAVKKVN---DPKQT---------------------ELKILR--KL
|. .  .|.|  |    |. |..|.                            .|||| .    .  |.                     |.|...  ..
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

SHPNIVKCLGVCNKPPC------------YCIVMEYCRLGN----LFDYIRKTSTK--------------------------------------------
 |||||...||| .. .            ..|||||. .|.    | || || . |                                            
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------IMPFDVIQWSREICTGMQFLHSK------KLIHRDLKSLNVLVSDNHS-----------MKITDFG---
                               . . . . ... |. ||..||||      ...||||   |.||..|.             ||.|||   
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----VSRTLDH--QFTKMT-------------------------VIGSVAWMAPELIRSEP---------CSEKVDIWSFGVCLWELLTRE-EPYKDLN
      .| ...    ....                             . ||||| ...           ...| |.|||||..||..|.  |||    
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

HG------------AVIYGVGSTT-----------LSLPIPTGCP--------------SDLKSLLQKCWQQKPKSRPSFSQIIEEL
.                   |...           . .| | .||               ..  |.|.||. .|. ||.|||. |.|
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL

Kinase AqueK655.AA STE 106-349 23 5.2e-62 212.33 In-house 1-359 (359) Show / Hide
Range on Protein: 106-349
Range on HMM: 1-359/359
Sequence Identity: 23% (85 aa)

IRELSYIGKGGQGAVFSGKYRDNE-----------------VAVKKVN--------------------DPKQ----TELKILRKLS--HPNIVKCLGVCN
 . .. ||||. | |. .....|                  .|.|..|                    . ..     |.||..|..  ||||||..| . 
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

KP-------PCYCIVMEYCRLGNLFDYIR---KTST---------KIMPFDVIQW-SREICTG-MQFLHSKKLIHRDLKSLNVLVSDNHSMKITDFGVSR
|           .|.|||.  | | | |.   ..           . .| ..| .  |.|. | ...|||.. ||||.|. |.|.      |..||||. 
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

TLDH-----------------QFTKMTVIGSVAWMAPELIRS------EPCSEKVDIWSFGVCLWELLTREEPYKDLNHG----AVI--YGVGS------
 |..                 |    |..|.  ||||| |.        ....|.||||.| ...|..| . |. |...     . .  |....      
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

----TTLSLPI-----------------PTGCPSDLKSLLQKCWQQKPKSRPSFSQIIE-ELNVI
    .  .||                  |. . ...|  ..|| |  |. ||. || .. |   |
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI

Kinase AqueK655.AA TK-Unique 106-287 29 6.7e-52 177.24 In-house 1-234 (294) Show / Hide
Range on Protein: 106-287
Range on HMM: 1-234/294
Sequence Identity: 29% (70 aa)

IRELSYIGKGGQGAVFSGKYR--------DNEVAVKKVNDPKQTE--------LKILRKLS-HPNIVKCLGVCNKPP-CYCIVMEYCRLGNLFDYIRKTS
.. ...||.|  | |. |...        .. ||||...|. . .        ......|  |||||.|||.| |.    .|.||||. ||| .|.|.. 
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR

TK-------------------------IMPFDVIQWSREICTGMQFLHS--KKLIHRDLKSLNVLVSDNHSMKITDFGVSR----TLDHQFTKMTVIGSV
 .                         |.|.|....  .|. ||..|.|  || .|||| . |||.....  ||.||| .|    . ... ..     ..
PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMCSQGRIPI

AWMAPELIR--SEPC-SEKVDIWSFGVCLWELLT
.||||| ..   ... ..| |.||||| .||..|
RWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFT

Kinase AqueK655.AA MLK 228-346 48 4.8e-51 166.83 In-house 163-280 (280) Show / Hide
Range on Protein: 228-346
Range on HMM: 163-280/280
Sequence Identity: 48% (58 aa)

DNHSMKITDFGVSRTLDHQFTKMTVIGSVAWMAPELIRSEPCSEKVDIWSFGVCLWELLTREEPYKDLNHGAVIYGVGSTTLSLPIPTGCPSDLKSLLQK
.|  .||||||. | . |. |.|   |  |||||| |..   |.  |.||.|| ||||||.|.||.     || |||   .| ||||  ||   . |.| 
CNKQLKITDFGLAREW-HKTTRMSAAGTYAWMAPEVIKESTWSKGSDVWSYGVLLWELLTGEVPYRGIDPLAVAYGVAMNKLTLPIPSTCPEPWAKLMQD

CWQQKPKSRPSFSQIIEEL
||.| | .||.||.|...|
CWNQDPHKRPKFSEILQQL

Kinase AqueK655.AA MLK 105-226 37 1e-25 81.79 In-house 2-136 (280) Show / Hide
Range on Protein: 105-226
Range on HMM: 2-136/280
Sequence Identity: 37% (52 aa)

DIRELSYIGKGGQGAVFSGKYRDNEVAVKKV-----NDPKQT---------ELKILRKLSHPNIVKCLGVCNKPPCYCIVMEYCRLGNLFDYIRKTSTKI
.|.|.  || || | |. . .. .|||||       .|. ||         | ...  |.||||.. .||| ..|  |.|||||| | |   ..      
KIKEI--IGNGGFGKVYRAQWKGEEVAVKAHRQDPEQDMQQTDEQAEQVRQEARLFWMLKHPNIIALRGVCLEDPHLCLVMEYCRGGSLNRVCAGK---R

MPFDV-IQWSREICTGMQFLHSKK---LIHRDLKSLNVLV
 | .| . |   |  ||..||      .||||||| |.|.
IPPHVLVNWAVQIARGMNYLHNEAPVPIIHRDLKSSNILI

Kinase AqueK655.AA TK-Unique 311-346 40 2.7e-12 38.82 In-house 258-294 (294) Show / Hide
Range on Protein: 311-346
Range on HMM: 258-294/294
Sequence Identity: 40% (15 aa)

LPIPTGC-PSDLKSLLQKCWQQKPKSRPSFSQIIEEL
.| | .| . .. .|.. ||| .|..||||.||. .|
MPQPEHCCSHEMYNLMKSCWQWEPEERPSFRQIKHRL