Gene AqueK660 (A.queenslandica)

AqueK660

Species: A.queenslandica
Alias: AqueK660
External Links:
Annotation:

Classification

Group: TKL
Family: MLK
Subfamily: MLK-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
AqueK660.AA Protein None 678 None Fasta, JSON
AqueK660.kin_dom Protein Kinase Domain None 199 None Fasta, JSON

Protein domain

Protein domains of AqueK660.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase AqueK660.AA Y_phosphatase 53-170 40 2.4e-40 143.06 Pfam 126-243 (243) Show / Hide 
Range on Protein: 53-170
Range on HMM: 126-243/243
Sequence Identity: 40% (50 aa)

TLTRFGDEQPEASYTLHHFQFLGWPERGVPVS-ALSLLQMIQNVQELYITLRTTE------PITVMCSSGVGRTGVFIALGIVLERYSVEGMIDLFQTVK
..|  ||. .. . |..|.....||..||| | . |.|..|. |.. .             ||.|.|| |.||||.|.|. |....   ||..|.||.||
EVTN-GDQ-KQETRTVTHYHYTNWPDHGVPESQPKSMLDFIRQVRKWQP-----NPDHGCPPIVVHCSAGCGRTGTFCAIDIMCQQMEHEGTVDIFQIVK

TLRIQRSAMVQTREQYHFCYEAILD
..| ||  |||| ||| |||..||.
HMRNQRPGMVQTEEQYIFCYQCILE
Kinase AqueK660.AA PTPc_motif 67-170 41 2.9e-36 127.7 SMART 1-92 (92) Show / Hide 
Range on Protein: 67-170
Range on HMM: 1-92/92
Sequence Identity: 41% (45 aa)

TLHHFQFLGWPER-----GVPVSALSLLQMIQNVQELYITLRTTEPITVMCSSGVGRTGVFIALGIVLERYSVEGMIDLFQTVKTLRIQRSAMVQTREQY
|.||.....||.      |||    |.|..|. |..         || |.|| |.||||.|.|. .....      .| ||||| .| ||  |||| |||
TVHHYHYTNWPDHVEKDSGVPE--DSILEFIRHVRK---------PIVVHCSAGCGRTGTFCAIDMMMQQ------VDIFQTVKEMRKQRPGMVQTEEQY

HFCYEAILD
 |||..||.
IFCYRCILE
PTPc AqueK660.AA PTPc 3-173 18 1.2e-09 6.44 SMART 1-308 (308) Show / Hide 
Range on Protein: 3-173
Range on HMM: 1-308/308
Sequence Identity: 18% (57 aa)

RAQLQPLLLPNL-------------KETGKELGRGA------YG-VV-----TEVI---------------------VSG--------------------
  . .   |...             . |  ..   .      |   .     | |.                     ..|                    
GFWEEFERLQRMTPWDLMSNYDPCCSCTCACWPENREMDKNRYKCDIPCYDHTRVKLKPPPGESHCYEGSDYINANYIDGYWRPKRYICTQGPLPHTIED

---------------------T-----------------------------TCAAKKLHPAIVQENTLTRFGDEQ-------PEASYTLHHFQFLGWPER
                                                   ||  .. .|. ..  |..   ...       .. . |..|... .||..
FWRMVWQQKCHIIVMLCNCMEKCTENRDQNGREKCHQYWPDEPMTYGHITVTCKSEEKCPDDYTMRTFEVTNTGCNCKYSMACSETRTVTHYHYTNWPDH

GVPVSALSLLQMIQNVQELYITLRT-----------------TEPITVMCSSGVGRTGVFIALGIVLERYSVEGMIDLFQTVKTLRIQRSAMVQTREQYH
||| |. |.|..|. | . . ...                  | || |.|| |.||||.|.|. |....      .|.||.||..| ||  |||| |||.
GVPESPDSFLDFIRQVRHWQSHSPNMYMNMVSSNSKYHHTCPTGPIVVHCSAGCGRTGTFCAIDIMCQQIEN---VDIFQIVKMMRNQRPGMVQTEEQYI

FCYEAILDYLL
|||..||.|..
FCYRCILEYIK
Kinase AqueK660.AA STE 15-45 18 0.002308 7.88 In-house 1-48 (359) Show / Hide 
Range on Protein: 15-45
Range on HMM: 1-48/359
Sequence Identity: 18% (9 aa)

KETGKELGRGAYGVVTEVIVS-----------------GTTCAAKKLH
 |  ...|.||.|.|   .                   |. .| |...
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMN
Kinase AqueK660.AA TKL 21-45 22 0.039514 3.48 In-house 1-35 (364) Show / Hide 
Range on Protein: 21-45
Range on HMM: 1-35/364
Sequence Identity: 22% (8 aa)

LGRGAYGVVTEVIVSG----------TTCAAKKLH
.|.|..|.|   .  |          .. | ||..
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFK
Kinase AqueK660.AA TK-Unique 15-45 31 0.073266 2.35 In-house 1-38 (294) Show / Hide 
Range on Protein: 15-45
Range on HMM: 1-38/294
Sequence Identity: 31% (12 aa)

KETGKELGRGAYGVVTEVIVSG-------TTCAAKKLH
 | |...|.||.| |    |.|       ..|.| |..
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKML
Kinase AqueK660.AA Dicty4 16-57 31 0.100256 1.73 In-house 2-45 (277) Show / Hide 
Range on Protein: 16-57
Range on HMM: 2-45/277
Sequence Identity: 31% (14 aa)

ETGKELGRGAYGVVTEVIVSGTTCAAKKL--HPAIVQENTLTRF
 .....|.|..| |   .. |.  | |||  |   . ||.|. |
NIEQRIGKGSFGEVYKGTWRGKEVAVKKLNNHNQNFDENMLNEF
Kinase AqueK660.AA LRRK 15-29 31 0.129766 1.46 In-house 1-16 (351) Show / Hide 
Range on Protein: 15-29
Range on HMM: 1-16/351
Sequence Identity: 31% (5 aa)

KETGKELGRGAYG-VV
 . ....|||..| .|
LKIEEQIGRGGFGTFV
Kinase AqueK660.AA MLK 15-29 26 0.135594 1.46 In-house 1-15 (291) Show / Hide 
Range on Protein: 15-29
Range on HMM: 1-15/291
Sequence Identity: 26% (4 aa)

KETGKELGRGAYGVV
 .. . .| |..|.|
IQFHEWIGSGSFGKV
Kinase AqueK660.AA Pkinase 15-29 33 1.459117 3.07 Pfam 1-15 (293) Show / Hide 
Range on Protein: 15-29
Range on HMM: 1-15/293
Sequence Identity: 33% (5 aa)

KETGKELGRGAYGVV
 ..|. .|.|..|.|
YHIGRKIGSGSFGCV
Kinase AqueK660.AA Pkinase_Tyr 16-29 57 2.875698 1.53 Pfam 2-15 (270) Show / Hide 
Range on Protein: 16-29
Range on HMM: 2-15/270
Sequence Identity: 57% (8 aa)

ETGKELGRGAYGVV
. ||.||.||.|.|
TFGKKLGEGAFGEV
Kinase AqueK660.AA TKL 244-436 22 1.6e-41 144.23 In-house 1-288 (364) Show / Hide 
Range on Protein: 244-436
Range on HMM: 1-288/364
Sequence Identity: 22% (66 aa)

LGRGAYGVVTEVIVSG----------TICAAKKLHDVIVQEYTL-------------------------TRFCDEVLLHSHQRHPNIVQLIG-VYYPPR-
.|.|..|.|   .  |          .  | ||..   ..| |.                          ..  |....|  |||||||..| . .||  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

---------SQLPMLVMEYLPL-S-LTQCLEREELSLQMKYSILLDVAKGLCYLHGKR------PPIVHRDLTANNVLLTSSYS--------------AK
         .  ...|||| |  | | . .      .. . .. ||.|.|..||| ..      |||.||||. .|.|. . .               .|
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCK

ISDLGVSRLADTFKKDHLTT------------------APGNASVMPPEALEDNP---------------VYDHKLDVFSYGCLILHVLTGQLP
|.|.| ||  .. ...  |                     |.   |.||.|....                |. | ||.|.| ..  .||...|
ICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRP
Kinase AqueK660.AA TK 241-427 17 1.8e-34 112.38 In-house 4-384 (486) Show / Hide 
Range on Protein: 241-427
Range on HMM: 4-384/486
Sequence Identity: 17% (68 aa)

GKELGRGAYG---VVTEVIVSG---------------------------TICAAKKLH---DVIVQEYTLT------------RFCDEVLLHSH--QRHP
||.||.|..|   .| . .. |                           | .| | |.   .   .|  .             ... |  . .|   .||
GKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLGHHP

NIVQLIGVYYPPRS----------QLPMLVMEYLPL-----SLTQCLE--REE-----------------------------------------------
|||.|.||   ...          . .|.|||| |.     || . |   |..                                               
NIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDYDDD

----------------------------LSLQMKYSILLDVAKGLCYLHGKRP----PIVHRDLTANNVLLTSSYS-----------AKISDLGVSR---
                            |... .  . ...|.|. ||| |.      .||||| | |.|.....            .||.| | ||   
LIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQGS

--LADTFKKDHLTTAPGNASV----------------------------MPPEALEDNP--------VYDHKLDVFSYGCLI
  ||    .|.  .. .. ..                            |.||.|.|.         .. .| ||.|.|.|.
GVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLM
S_TKc AqueK660.AA S_TKc 238-499 22 2.6e-32 114.58 SMART 1-231 (231) Show / Hide 
Range on Protein: 238-499
Range on HMM: 1-231/231
Sequence Identity: 22% (65 aa)

KETGKELGRGAYGVVTEVIV--SGTICAAKKLHDVIVQEYTLTRFCDEVLLHSHQRHPNIVQLIGVYYPPRSQLPMLVMEYLPL---SLTQCLEREE---
 | ....|.||.|.|  ..   .| |.| |...          ... |. .... .|||||.|..|..    .   .||||..    .| . ...     
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHG

----LSLQMKYSILLDVAKGLCYLHGKRPPIVHRDLTANNVLLTSSYSAKISDLGVSRLADTFKKDHLTTAPGNASVMPPEALEDNPVYDH-KLDVFSYG
    ..  .  ...  ....| |.| .   |.||||   |.||..    ||.| |..|.         ||  |    |.|| |     |.. | |. | |
LRFPFPE-HARFYMYQICCALEYCHSH--GIIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL----GYGKCKCDWWSCG

CLILHVLTGQLPKPTKEYAPEPGKKKSFKKVPEWERRSNYIKNIPKENELLFLAKRCLSDIPTGRPEIVDSCH---------FV
|..   |.|. | |          .. |||.                 |.. . ..||   |. || . .  .         ..
CILYEMLCGYPPFP--------QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK660.AA TKL-Unique 240-424 28 3.8e-30 103.6 In-house 1-215 (290) Show / Hide 
Range on Protein: 240-424
Range on HMM: 1-215/290
Sequence Identity: 28% (62 aa)

TGKELGRGAYGVVTEVIVSGTICAAKKLHDVIVQEYTLTR-FCDEVLLHSHQR-HPNIVQLIGVYY---PPRSQLPMLVMEYLPL-SLTQCLE-------
 .. .|.|.||.|  ..  |.. | |..|    .. .... | .|| . .  . |||||...|.     .. ...  .||||.|. ||   |        
FWNKIGEGGYGQVYKGKWRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNM-CIVMEYCPGGSLYDVLHQNNNNNN

----REELSLQMKYSILLDVAKGLCYLHGKRPPIVHRDLTANNVLLTSS-----YSAKISDLGVSRLADTFKKDHLT--------TAPGNASVMPPEALE
      .|..|..... .|.|.|..||| . ||| ||||.  |.|...      ...||.| | |.....  |  ..        |  |..  |.|| |.
NNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLR

DN-PVYDHKLDVFSYG
.|   |. | ||.|.|
MNFCQYSEKSDVYSFG
Kinase AqueK660.AA HH498 330-436 38 1.3e-28 87.56 In-house 118-225 (284) Show / Hide 
Range on Protein: 330-436
Range on HMM: 118-225/284
Sequence Identity: 38% (42 aa)

LSLQMKYSILLDVAKGLCYLHG-KRPPIVHRDLTANNVLLTSSYSAKISDLGVSRLADTFKKDHLTTAPGNASVMPPEALEDNPVYDHKLDVFSYGCLIL
..|| |  | .|||.|  |||    .||.||||.  |.|.     |.. | | ||       | .|  |||   | ||    .  |. | |||||.  | 
MDLQSKMTISVDVAHGMNYLHNSLKHPIIHRDLNSHNILIHEDGHAVVADFGESRFVCDMHDDNMTKQPGNLRWMAPEVFSQCQKYSIKVDVFSYAMCIW

HVLTGQLP
  .|. .|
EMHTREVP
Kinase AqueK660.AA LRRK 283-436 35 2.1e-28 97.61 In-house 107-282 (351) Show / Hide 
Range on Protein: 283-436
Range on HMM: 107-282/351
Sequence Identity: 35% (64 aa)

EVLLHSHQRHPNIVQLIGVYYPPRSQLPMLVMEYLPL-SLTQCLE---REE-------LSLQMKYSILLDVAKGLCYLHGKRPPIVHRDLTANNVLLTSS
|| . || .|||||.|.|.   |.    ..||||.|. .| . |.   . .       .| ..|. | |..|||. ||| ..|||.||||.  |.|| ||
EVWIMSHLNHPNIVSLKGFCIHPL----CMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNPPIIHRDLKSPNILLWSS

------------YSAKISDLGVSR-LADTFKKDHLTTAPGNASVMPPEALEDN--PVYDHKLDVFSYGCLILHVLTGQ-LP
            . |||.| | ||    .|..  . .  ||   | || . .|   .|. | |..|.| .. . ||.| .|
PQNHSPNYPNAHVCAKIADFGISRMF-QCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHP
Kinase AqueK660.AA Pkinase_Tyr 239-427 28 3.8e-28 95.96 Pfam 2-204 (270) Show / Hide 
Range on Protein: 239-427
Range on HMM: 2-204/270
Sequence Identity: 28% (60 aa)

ETGKELGRGAYGVVTEVIVS------GTICAAKKLHDVIVQEY-TLTRFCDEVLLHSHQ-RHPNIVQLIGVYYPPRSQ-LPMLVMEYLPL-SLTQCLERE
. ||.||.||.|.| . .        .. .| |.| .   .|   .  |  |. . ..  .|||||.|.|| .. . .  ...|||| |. .|   | . 
TFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKH

-----ELSLQMKYSILLDVAKGLCYLHGKRPPIVHRDLTANNVLLTSSYSAKISDLGVSRLADTFKKDHL--TTAPGNASV--MPPEALEDNPVYDHKLD
      |..... .. ...|||. ||. |.  ..|||| | |.|.|..  .||.| | .|.   ...|    ..  |   .  |.||.. ..  . .| |
REDKQPLTMKDLLQMCWQIAKGMEYLESKN--CIHRDLAARNCLVTENNVVKICDFGLARDI--YNDDYYYRKRGGGKLPIKWMAPECINYGK-FTTKSD

VFSYGCLI
| |.| |.
VWSFGVLM
Kinase AqueK660.AA Dicty4 239-424 30 3.2e-27 87.97 In-house 2-204 (277) Show / Hide 
Range on Protein: 239-424
Range on HMM: 2-204/277
Sequence Identity: 30% (63 aa)

ETGKELGRGAYGVVTEVIVSGTICAAKKL--HDVIVQEYTLTRFCDEVLLHSHQRHPNIVQLIGVYYPPRSQL--PMLVMEYLPL-SLTQCLER------
 .....|.|..| |   .. |.. | |||  | . . |..|. |  || . .  |||||... |    |||.   .. |.||.|  .|   |        
NIEQRIGKGSFGEVYKGTWRGKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSEQQ

EELSLQ--MKYS---ILLDVAKGLCYLHGKRPPIVHRDLTANNVLLTSSYSAKISDLGVSR--LADTFKKDHLTTAPGNASVMPPEALEDNPVYDHKLDV
.. .|.     .   . .|.|.|. .||.  | |.|||| . | |   .. .|..|.| |.    .. .|| ..|| | .  | || .  .| |. | ||
QSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQP-YNEKADV

FSYG
.|.|
YSFG
Kinase AqueK660.AA STE 238-436 22 4.8e-27 92.61 In-house 1-267 (359) Show / Hide 
Range on Protein: 238-436
Range on HMM: 1-267/359
Sequence Identity: 22% (61 aa)

KETGKELGRGAYGVVTEVIVS-----------------GTICAAKKLH---------------DVIVQEYTLTRFCDEVLLHSHQR--HPNIVQLIGVYY
 |  ...|.||.|.|   .                   |.|.| |...               . ....  . ..  |. .... .  |||||. .| |.
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

---PP---RSQLPMLVMEYLP-LSLTQCLER-----EELS----------LQMKYSILLDVAKG-LCYLHGKRPPIVHRDLTANNVLLTSSYSAKISDLG
   ..   ...|  ..|||..  ||.. ...     ..|.           .    |. .. || | ||| ..  |.|||. . |.||     .|..| |
KEGHNHKNDDEL-WICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH--IIHRDIKPANILL-----VKLCDFG

VSR-LADTFKKD--------------HLTTAPGNASVMPPEALED-----NPVYDHKLDVFSYGCLILHVLTGQLP
|.  |.|.  ..              . .|  |    | || ..      .. || | |. | ||.|.. .||. |
VCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPP
Kinase AqueK660.AA MLK 238-436 24 2.2e-26 88.6 In-house 1-235 (291) Show / Hide 
Range on Protein: 238-436
Range on HMM: 1-235/291
Sequence Identity: 24% (58 aa)

KETGKELGRGAYGVVTEVIVSGTI-----CAAKKLH----DVIVQEYTLTRFCDEVLLHSHQRHPN----IVQLIGV-YYPPRSQLPMLVMEYLPL-SLT
 .. . .| |..|.|      ...      | |. .    |. . .     |  |. . .. .|||    |.|. ||   ||  .   .||||..  || 
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPP--CHFCIVMEYCEGGSLY

QCLEREE---------------LSLQMKYSILLDVAKGLCYLHG-KRPPIVHRDLTANNVLLTS------SYSAKISDLGVSRLADTFKKDH---LTTAP
  |  ..                ... . .. |..|.|. |||  ...||.||||   |.|..          .||.| |.||    .....    . ..
NVLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSR----DWHQMCTNMMSNA

GNASVMPPEALE--DNPVYDHKLDVFSYGCLILHVLTGQLP
|..  | ||...   .  |. | ||.|.| ..  .||...|
GTYAWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVP
Kinase AqueK660.AA Pkinase 238-438 25 2.1e-25 90.91 Pfam 1-213 (293) Show / Hide 
Range on Protein: 238-438
Range on HMM: 1-213/293
Sequence Identity: 25% (56 aa)

KETGKELGRGAYGVVTEVIVSGT-----ICAAKKLHDVIVQEYTLTRFCDEVLLHSHQRHPNIVQLIGVYYPPRSQLPMLVMEYLPL-----SLTQCLE-
 ..|. .|.|..|.| . .  ||     .   || |.   ...|..|   |. .. . .|||||.|.....   .. . .||||..      .|   .. 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRL-SEIQIMKRLNHPNIVRLYDWFED--KDHIYMVMEYCEGGLYVMDLFDYIST

REELSL--QMKY--SILLDVAKGLCYLHGKRPPIVHRDLTANNVLLTSSYSA----KISDLGVSRLADTFKKDHLTTAPGNASVMPPEALEDNPVYDHKL
... ..  ...   .... ...|| |.| .   |.||||   |.|. . .      ||.| |.....|. ..  .||  |    |.|| . ... |..| 
WRHGCFYFSEWECKFYMYQILRGLEYCHSM--GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKV

DVFSYGCLILHVLTGQLPKP
|..|.||..  .|.|..| |
DMWSCGCILYEMLCGRPPFP
Kinase AqueK660.AA TK-Unique 238-427 26 1.8e-23 77.89 In-house 1-229 (294) Show / Hide 
Range on Protein: 238-427
Range on HMM: 1-229/294
Sequence Identity: 26% (63 aa)

KETGKELGRGAYGVVTEVIVSG-------TICAAKKLHDVIVQEYTLTRFCDEVLLHSHQR-HPNIVQLIGVYYPPRSQLPMLVMEYLPLS-----LTQC
 | |...|.||.| |    |.|       ..|.| |..   ... .   | .|  ....   ||||||..|.   .  . .|..|||.| .     | .|
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSD-EPWMIIMEYCPCGNLQHYLRTC

L-----------------------EREELSLQMKYSILLDVAKGLCYLHGKRPPIVHRDLTANNVLLTSSYSAKISDLGVSR-------LADTFKKDHLT
                        ..|..|..  |... ..|.|. ||.. |  |||||| | |||||. . .||.|.| .|       .. . ..  . 
RPAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMCSQGRIP

TAPGNASVMPPEALE--DNPVYDHKLDVFSYGCLI
 .      |.||.|   ... .  | || |.|.|.
IR-----WMAPESLKCYHGMYHTTKSDVWSFGVLM
Kinase AqueK660.AA Ciliate-E2 238-468 15 2.8e-22 73.29 In-house 1-300 (365) Show / Hide 
Range on Protein: 238-468
Range on HMM: 1-300/365
Sequence Identity: 15% (52 aa)

KETGKELGRGAYGVVTEVIVSGTIC-------------------AAKKLHDVIVQEYTLTRFCDEVLLHS-----------------HQRHPNIVQLIGV
 .  | .|.|..|.| .. |  . .                   ...|.  . ...    ..   ..                    .  ||||.... .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

YYPPRSQLPMLVMEYLPL-SLTQCLE------REE------LSLQMKYSILLDVAK---------------GLCYLHGKRPPIVHRDLTANNVLLTSSYS
..    .   |||||.   .| ....       .|      ....    |   ...               .| ||| | . |.|||.  .|.|.     
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNN-IIHRDIKPENILF-----

AKISDLGVSRLADTFKKDHL--------------TTAPG----------------NASVMPPEALEDNPV--------YDHKLDVFSYGCLILHVLTGQL
 ||.|.| |. .|.. ....              .. ||                ..  |.|| |.  .         ||.| |..| |...   |.|..
IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP

PKPTKEYAPEPGKKKSFKKVPEWERRSNYIKNI
|                            ...|
PF---------------------------QQQI
Kinase AqueK660.AA TyrKc 238-499 26 1e-17 63.67 SMART 1-280 (280) Show / Hide 
Range on Protein: 238-499
Range on HMM: 1-280/280
Sequence Identity: 26% (77 aa)

KETGKELGRGAYGVVTEVIVSGTICAAKKLHDVIVQEYTLTRFCDEVLLHSHQ--RHPNIVQLIGVYYPP-----RSQLPMLVMEYLPL-SLTQCLEREE
 . ||.||.||.|.| . . . . .| |.|..       .  |..|  . ..   .|||||.|.||   .      .. .|.|||| |. .| . | . .
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR

--LSLQMKYSILLDVAKGLCYLHGKRPPIVHRDLTANNVLLTSSYSAKISDLGVSRLADTF-----KKDHLTTA---PGN--ASV--MPPEALEDNPVYD
  |... . |. ...|.|  ||| |  ...|||| | |.|... . .|||| | ||  .        ||  ...    |.    .  |.||.. .  .. 
PKLCMKDLLSFCWQIACGMEYLHSK--NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-NYGKFT

HKLDVFSYGCLILHVLT-GQLPKPTKEYAPEPGKKKSFKKVPEWERRSNYIKNIPK---------ENELLFLAKRCLSDIPTGRPEIVDSCHFV
.| ||.|.| ..  ..| || | |  .       ..| . | |. .. .. .  |            |.  . |.|    |  ||   . ... 
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQ-----MMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase AqueK660.AA LRRK 238-252 31 0.129766 1.46 In-house 1-16 (351) Show / Hide 
Range on Protein: 238-252
Range on HMM: 1-16/351
Sequence Identity: 31% (5 aa)

KETGKELGRGAYG-VV
 . ....|||..| .|
LKIEEQIGRGGFGTFV